Online world of liquid chromatography

News

Article | Interview

Why Biologics QC Is So Much Harder Than Small Molecule Pharma

Colette Quinn discusses how LC, high-resolution MS, light scattering, automation and data literacy are transforming QA/QC for increasingly complex biologics.

Fr, 28.8.2026

Organomation

Article | Science and research

Unassuming Start–Stop “Gates” Regulate Protein Production in Cells

A study in Nucleic Acids Research shows that short start–stop elements act as highly effective translation gates, helping control protein synthesis even under cellular stress.

Fr, 28.8.2026

Czech Academy of Sciences

Article | Science and research

New Antibiotics Designed on a Computer: Scientists Develop a Blueprint for Building Molecules Against Drug-Resistant Bacteria

CEITEC-led researchers developed a computational method to design antimicrobial peptides that form pores in bacterial membranes and kill drug-resistant pathogens, with efficacy confirmed in mouse models.

Th, 27.8.2026

CEITEC

Article | Application

News from LabRulezLCMS Library - Week 35, 2026

This week we bring you application notes by Agilent Technologies, Thermo Fisher Scientific, Shimadzu and Waters Corporation!

We, 26.8.2026

LabRulez

Instruments and services

Waters Xevo MRT P10 QTof Mass Spectrometer

Ultra-fast HRMS with MRT technology delivering up to 20× higher MS/MS sensitivity, 200 Hz acquisition speed, and exceptional performance for multiomics and imaging applications.

Determination of Explosives in Soil and Water Samples (ALS Global)

Monitoring, determination, and treatment of environmental contamination by explosives (TNT, RDX, HMX, nitrobenzene, etc.) using HPLC-DAD. ALS performs analyses of 20 target compounds in water and soil.

Shimadzu UV-1900i Plus UV-VIS spectrophotometer

UV-1900i Plus delivers 1 nm resolution, ultra-fast scanning, and intuitive operation for precise UV-Vis analysis compliant with JP, USP, and EP.

Modern HPLC separations in theory and practice

This book is a unique combination of theory and practice, but also overviews of stationary phases, sample prep materials, and vendor’s brief presentations.

Thermo Scientific Stellar Mass Spectrometer

Move biomarker candidates from discovery to validation more efficiently, confidently, and at lower cost with breakthroughs in extended scale, massive throughput, higher sensitivity, greater specificity, and unrivaled productivity.

Waters Xevo MRT QTof Mass Spectrometer

Achieve exceptional science with the Xevo™ MRT Mass Spectrometer—100K resolution at 100 Hz, sub-ppm accuracy, and confident identification for greater lab productivity.

DataApex Clarity Chromatography Software

Clarity is a chromatography data software for data acquisition, processing, and instrument control in regulated environment. Clarity is a flexible solution for devices from different vendors, supporting different applications.

Advanced PFAS Analytical Services (ALS)

Comprehensive PFAS analysis in water, soil, sludge, and AFFF sites using LC-MS/MS. Detect 60+ PFAS compounds, meet EU limits, and ensure compliance with evolving 2025 regulations.

Wiley LC-MSⁿ Library of Drugs, Poisons and Their Metabolites, 2nd Edition

The Maurer/Wissenbach/Weber LC-MSⁿ Library, 2nd Ed., offers MS² and MS³ spectra for over 2,270 drugs and 3,600+ metabolites. It enables proven metabolite-based LC-MSⁿ screening and is one of the few libraries focused on metabolite spectra.

Thermo Scientific Orbitrap Astral Mass Spectrometer

A new horizon for single-cell, quantitative, and translational proteomics.

Thermo Scientific Orbitrap Astral Zoom Mass Spectrometer

Orbitrap Astral Zoom boosts flexibility, speed, sensitivity, and quantitation for Omics and Biopharma with hybrid DIA, TMT HR modes, and next-gen acquisition.

Waters Alliance iS HPLC System

Waters™ delivers a reliable partner for QC labs. The Alliance™ iS HPLC System enhances efficiency, reduces errors, and simplifies workflows - your new essential lab ally.

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Waters Xevo MRT P10 QTof Mass Spectrometer

Ultra-fast HRMS with MRT technology delivering up to 20× higher MS/MS sensitivity, 200 Hz acquisition speed, and exceptional performance for multiomics and imaging applications.

Determination of Explosives in Soil and Water Samples (ALS Global)

Shimadzu UV-1900i Plus UV-VIS spectrophotometer

UV-1900i Plus delivers 1 nm resolution, ultra-fast scanning, and intuitive operation for precise UV-Vis analysis compliant with JP, USP, and EP.

Marketplace

Shimadzu LC-10 HPLC System – Complex Modular Configuration (Tested)

Complex modular Shimadzu LC-10 HPLC system with two pumps, autosampler, column oven, degasser, PDA and fluorescence detectors, system control, and automated fraction collection. Suitable for gradient analysis, spectral detection, and collection of separated fractions.

Purchase price3,000€without VAT

In stock

Agielnt Octopole PCA for 61XX, 64XX series, G1960-65022 (Tested)

Original Agilent G1960-65022 Octopole PCA for Agilent 61XX and 64XX Series LC/MS mass spectrometers. Printed circuit assembly (PCA) designed to control the instrument's octopole ion optics.

Purchase price1,000€without VAT

In stock

Agilent 1220 Infinity II LC System – Gradient Pump, ALS, Column Heater, DAD, G4294B (New)

Complete Agilent 1220 Infinity II LC System (G4294B) equipped with a gradient pump, autosampler, column heater, and diode array detector. A compact and reliable HPLC platform designed for routine analytical laboratories requiring reproducible performance and seamless integration with Agilent InfinityLab software.

Purchase price27,500€without VAT

In stock

Agilent Quad Driver Assembly for Agilent 6490 LC/QQQ, G2571-60274 (Tested)

The Agilent G2571-60274 Quad Driver Assembly is a genuine RF electronic module designed for the Agilent 6490 Triple Quadrupole LC/MS system. It generates and controls the radio-frequency voltages required for quadrupole mass filtering, ensuring stable ion transmission and accurate mass analysis

Purchase price5,650€without VAT

In stock

Agilent Cary 3500 UV-Vis Compact, G9864A (Refurbished)

The Agilent Cary 3500 Compact UV-Vis is a double-beam spectrophotometer with an integrated air-cooled Peltier system and xenon flash lamp for accurate ambient and temperature-controlled UV-Vis measurements.

Purchase price8,500€without VAT

In stock

BUCHI Rotavapor R-300 EL Rotary Evaporator with B-300 Base Heating Bath and V-300 Vacuum Pump (Tested)

The BUCHI Rotavapor® R-300 with the B-300 heating bath and V-300 vacuum pump is a modular rotary evaporation system designed for automated laboratory distillation. It combines precise vacuum control, intelligent process management, flexible configuration, and reliable performance for evaporation, concentration, extraction, and synthesis workflows.

Purchase price6,500€without VAT

In stock

Metrohm 850 Professional IC System with 872 Extension Module, Dual 887 UV/VIS Detectors and 919 IC Autosampler plus (Tested)

This Metrohm Professional IC configuration integrates ion chromatography, advanced inline sample preparation, automated sample handling, and dual UV/VIS detection into a single platform. It is designed for laboratories requiring flexible, highly automated workflows with excellent reproducibility and analytical performance.

Purchase price25,000€without VAT

In stock

Memmert Vacuum oven VO400 (Tested)

The Memmert VO400 is a 49 L laboratory vacuum oven with digital vacuum control and temperatures up to 200 °C for gentle drying of heat- and oxidation-sensitive materials.

Purchase price4,900€without VAT

In stock

Agilent InfinityLab Assist hub, G7179-64000 (new)

Communication interface for Agilent InfinityLab LC systems, designed to coordinate instrument modules and support efficient laboratory automation.

Purchase price2,100€without VAT

In stock

Hygiena® SystemSURE Plus EnSURE Luminometer (Refurbished)

The Hygiena EnSURE ATP luminometer provides rapid hygiene verification, sanitation monitoring, and microbial indicator testing in a compact, easy-to-use platform for quality-driven environments.

Purchase price950€without VAT

In stock

Thermo Scientific MSQ Plus Mass Spectrometer with AXP-MS Auxilari Pump (Tested)

The Thermo Scientific MSQ Plus with AXP-MS and Edwards E2M30 is a compact single quadrupole LC/MS system with high sensitivity, ESI/APCI support, and a robust vacuum solution.

Purchase price14,000€without VAT

In stock

Peak Scientific Genius NM32LA nitrogen generator NM32LA (Tested)

The Peak Scientific Genius NM32LA is a compact LC-MS nitrogen generator with an integrated compressor, up to 32 L/min flow rate, and low operating costs.

Purchase price7,500€without VAT

In stock

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Shimadzu LC-10 HPLC System – Complex Modular Configuration (Tested)

Purchase price3,000€without VAT

In stock

Agielnt Octopole PCA for 61XX, 64XX series, G1960-65022 (Tested)

Original Agilent G1960-65022 Octopole PCA for Agilent 61XX and 64XX Series LC/MS mass spectrometers. Printed circuit assembly (PCA) designed to control the instrument's octopole ion optics.

Purchase price1,000€without VAT

In stock

Agilent 1220 Infinity II LC System – Gradient Pump, ALS, Column Heater, DAD, G4294B (New)

Purchase price27,500€without VAT

In stock