Join us for a free two-day LECO Separation Science Workshop on September 23–24, 2026, at the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/219">C³AL Laboratory</a> at Cal State LA. Registration is free, and meals and refreshments will be provided throughout the workshop.&nbsp;<h4>Registration</h4><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://forms.cloud.microsoft/pages/responsepage.aspx?id=iYeNbqIuykW7qZP4_jUEVbznDB40eK1PgjPzhHyb__9URTFTTFA5UEEzQ1A4MUtFV0o4TEJTNlZCOS4u&amp;route=shorturl">Register HERE</a>Space is limited, register today!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg" alt="LECO: LECO Separation Science Workshop - QR code for registration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg 156w," sizes="100vw" width="437" height="437"></blockquote><h4>Hand-on Experience with the LECO Complex Chemical Composition Analysis Lab C3AL</h4><ul><li>Work directly with LECO instruments in the C3AL Laboratory</li><li>Learn complete analytical workflows from sample to answer</li><li>Get expert guidance from LECO application scientists</li><li>Develop methods and solve real-world challenges</li><li>Collaborate, ask questions, and build your skills</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg" alt="Cal State LA: The LECO Pegasus BTX system in Cal State LA’s LECO Complex Chemical Compositional Analysis Lab enhances research and student training in advanced chemical analysis" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg 227w," sizes="100vw" width="1252" height="863">The first day will focus on the fundamentals and theory of comprehensive two-dimensional gas chromatography (GC×GC), with an emphasis on understanding how GC×GC can enhance your research, solve complex analytical challenges, and support your laboratory or company goals.&nbsp;The second day will be dedicated to hands-on activities, giving participants the opportunity to work directly with LECO instrumentation, learn practical analytical workflows, and analyze their own samples with guidance from LECO application scientists.&nbsp;Whether you are new to GC×GC or looking to expand its use in your research or organization, this workshop offers a unique opportunity to learn, explore, and apply the technology in a practical setting. Space is limited, so register early!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg" alt="Cal State LA: LECO QUADJET GCxGC coupled to Pegasus BT 4D TOM MS in the Complex Chemical Composition Analysis Lab (C³AL)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/thumbnail_Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg 234w," sizes="100vw" width="1949" height="1299">

LECO Separation Science Workshop

Taťána Gazárková is currently a&nbsp;postdoctoral fellow in the Laboratory of Antibiotic Resistance and Microbial Metabolomics. During her doctoral studies, she focused on chromatography and mass spectrometry. Recently, she was awarded second place in the “Sanofi Prize for Pharmacy 2026” competition.Taťána Gazárková is currently a&nbsp;postdoctoral fellow in the Laboratory of Antibiotic Resistance and Microbial Metabolomics. During her doctoral studies, she focused on chromatography and mass spectrometry. Recently, she was awarded second place in the “Sanofi Prize for Pharmacy 2026” competition, which is awarded by the French Embassy in the Czech Republic for her dissertation – Steroid Analysis Using Modern Chromatographic and Mass Spectrometry Techniques: From Fundamental Studies to Targeted Bioanalytical Applications (supervisor: Lucie Nováková, Charles University).&nbsp;<h5>What makes this field particularly exciting or unique in your view?</h5>What I&nbsp;enjoy about analytical chemistry is that, to a&nbsp;certain extent, it is a&nbsp;kind of detective work. You are often looking for ways to “make the invisible visible”. In other words, extract the information you are interested in from a&nbsp;complex sample and then interpret it correctly. What also appeals to me about bioanalytical chemistry is its interdisciplinary nature. It brings together analytical chemistry, biochemistry, biology and medicine, which means that you need to be able not only to translate a&nbsp;biological or clinical question into a&nbsp;measurable analytical experiment, but also to place the resulting data back into a&nbsp;broader biological context. This combination of different perspectives is probably what I&nbsp;enjoy most about the field. At the same time, there is still plenty of room for fundamental research, ranging from studying analytical techniques themselves and improving them to developing new methodological approaches.<h5>How did you end up at the <a target="_blank" rel="noopener noreferrer" href="https://mbu.cas.cz/en/research/laboratory-of-antibiotic-resistance-and-microbial-metabolomics">Laboratory of Antibiotic Resistance and Microbial Metabolomics</a>, and what project are you currently working on?</h5>I came to the Institute of Microbiology through a&nbsp;joint project between Dr Zdeněk Kameník and Assoc. Prof. Jan Bobek from the First Faculty of Medicine, Charles University. For me, it was also an opportunity to move from targeted analysis and the study of chromatographic techniques towards untargeted metabolomics and new biological questions.In the project, we are trying to identify new biologically active compounds that would be effective, particularly against pathogenic fungi. As a&nbsp;potential source of such compounds, we study streptomycetes, bacteria known for their ability to produce a&nbsp;wide range of biologically active compounds, including many antibiotics that are currently in clinical use. We focus on less-explored host-associated streptomycetes, in which we had already observed antifungal activity in previous experiments. We are especially interested in strains active against Candida albicans whose activity cannot be explained by the presence of a&nbsp;known bioactive compound. These strains may represent an interesting source of novel compounds. We then integrate the results of untargeted metabolomic analyses with genomic analyses, which allows us to obtain a&nbsp;more comprehensive view of the biosynthetic potential of selected strains.<h5>You also took part in this year’s Vědafest, a&nbsp;science outreach event for the public. What was it like?</h5>I already had some experience with science outreach through events such as Researchers’ Night and the Science Fair at my previous institution, but this year’s Vědafest was still new to me in some ways. This time, I&nbsp;was presenting a&nbsp;field that I&nbsp;myself had entered only relatively recently. It was therefore more challenging to find the right analogies and explain the essence of the topic in a&nbsp;way that was simple, yet precise and scientifically accurate. At the same time, that was exactly what made it inspiring. It forces you to look at your own work from a&nbsp;different perspective. What I&nbsp;enjoyed most was the spontaneity and curiosity of the children, who often came up with questions that would never even occur to an adult.<h5>What are the biggest challenges you face on your scientific journey, and what helps you overcome them?</h5>One of the greatest, but at the same time most interesting, challenges is, in my view, the uncertainty that is inseparably linked to research. For a&nbsp;long time, you often do not know whether you have taken the right direction in addressing a&nbsp;particular question or whether you will ultimately manage to find that figurative final piece of the puzzle. At the same time, this uncertainty is precisely what makes science exciting for me.Another major challenge, particularly in interdisciplinary projects, is communication. It is important from the very formulation of a&nbsp;hypothesis and the planning of experiments through to the interpretation of results, including negative ones, and placing them in a&nbsp;broader context. To some extent, every field has its own language, and finding a&nbsp;common understanding is not always straightforward. Personally, I&nbsp;find it very helpful to be able to discuss problems with colleagues on an ongoing basis, whether individually or during regular laboratory seminars. One of the major strengths of our current group is its interdisciplinary nature, which allows me to look at the same problem from several different perspectives. It is also important for me not to lose my curiosity, because that is ultimately what leads us to ask further questions.<h5>What are your plans after completing your PhD?</h5>After finishing my PhD, I&nbsp;decided that I&nbsp;do not need to have everything that comes next precisely mapped out straight away. I&nbsp;would like to keep different options open for a&nbsp;while and continue building on my experience in analytical chemistry, while at the same time connecting it with other areas that have a&nbsp;biological or medical relevance. I&nbsp;believe that we can keep learning throughout our lives, so I&nbsp;am quite curious to see where the next stage of my journey will take me.Thank you for the interview!

Interview: What Drew Postdoc Taťána Gazárková to Analytical Chemistry

Scientists at CEITEC Brno University of Technology have developed microscopic robots that could one day accelerate beer production and simplify food quality control. The magnetically controlled biobots can actively mix liquids during fermentation, speed up the process, and separate themselves from the finished product once fermentation is complete. The results of the research, carried out by Professor Martin Pumera’s team, were published in the journal ACS Nano.“When people hear the word ‘robot’ today, they often imagine an electronic device. In reality, however, a robot can be any system capable of autonomously performing a specific task,” explains Martin Pumera of CEITEC Brno University of Technology.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Mikroroboti_z_CEITEC_mohou_urychlit_vyrobu_piva_i_kontrolu_kvality_potravin_7d9ff82875.jpeg" alt="CEITEC BUT/Jakub Rozboud: CEITEC Microrobots Could Speed Up Beer Production and Food Quality Control: Martin Pumera in his lab at CEITEC BUT." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Mikroroboti_z_CEITEC_mohou_urychlit_vyrobu_piva_i_kontrolu_kvality_potravin_7d9ff82875.jpeg 235w," sizes="100vw" width="1600" height="1067">The research team created so-called biobots—biohybrid microrobotic capsules containing brewer’s yeast and magnetic nanoparticles. When the yeast produces carbon dioxide during fermentation, the resulting bubbles cause the biobots to move up and down through the liquid. This naturally mixes the contents of the vessel and makes fermentation more efficient. Compared with conventional static particles, the biobots can therefore accelerate chemical processes that are important in food production.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Mikroroboti_z_CEITEC_mohou_urychlit_vyrobu_piva_i_kontrolu_kvality_potravin_4_af5fd4611f.jpg" alt="CEITEC BUT/Martin Pumera's archive: CEITEC Microrobots Could Speed Up Beer Production and Food Quality Control: Hematite microrobot (image for illustrative purposes)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Mikroroboti_z_CEITEC_mohou_urychlit_vyrobu_piva_i_kontrolu_kvality_potravin_4_af5fd4611f.jpg 209w," sizes="100vw" width="1600" height="1192">Another major advantage of the technology is that the biobots can be easily separated from the finished beverage. Thanks to the magnetic particles they contain, they can be controlled with a magnetic field and removed once fermentation is complete, eliminating the need for additional filtration. The researchers also demonstrated that the biobots can be reused over several production cycles.“Unlike conventional static particles, microrobots actively move throughout the entire volume of the liquid, allowing them to cover a larger area and make the whole process more efficient. At the same time, they also facilitate the automation of production,” adds Martin Pumera. The team is currently discussing potential applications of the technology with a major European brewery.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Mikroroboti_z_CEITEC_mohou_urychlit_vyrobu_piva_i_kontrolu_kvality_potravin_3_e8e5a3a55a.jpg" alt="CEITEC BUT/Martin Pumera's archive: CEITEC Microrobots Could Speed Up Beer Production and Food Quality Control: g-C₃N₄ microrobots (image for illustrative purposes)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Mikroroboti_z_CEITEC_mohou_urychlit_vyrobu_piva_i_kontrolu_kvality_potravin_3_e8e5a3a55a.jpg 158w," sizes="100vw" width="1476" height="1460">Martin Pumera’s group has long been exploring the use of microrobots and advanced materials in the food industry. In the past, for example, the team developed a flexible sensor for smart packaging capable of detecting spoiled fish. The new biobots therefore represent another step towards more advanced methods of food quality and safety control.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Mikroroboti_z_CEITEC_mohou_urychlit_vyrobu_piva_i_kontrolu_kvality_potravin_2_75c7fed958.jpeg" alt="CEITEC BUT/ACS Nano: CEITEC Microrobots Could Speed Up Beer Production and Food Quality Control: ACS Nano - cover featuring article by Martin Pumera et al." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Mikroroboti_z_CEITEC_mohou_urychlit_vyrobu_piva_i_kontrolu_kvality_potravin_2_75c7fed958.jpeg 117w," sizes="100vw" width="1600" height="2128">

 CEITEC Microrobots Could Speed Up Beer Production and Food Quality Control 

Article

Events

Scientists

Food

Interview

Science and research

The Czech Academy of Sciences (CAS) was established by Act No. 283/1992 Coll. as the Czech successor of the former Czechoslovak Academy of Sciences. It is set up as a complex of 54 public research institutions.

Czech Academy of Sciences

Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

CEITEC

In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

LECO

Phenomenex Strata CN Solid Phase Extraction (SPE)

Strata CN is a polar phase with slight hydrophobic selectivity in reversed phase mode and moderate polar selectivity in normal phase mode.

Normal Phase Solid Phase Extraction (SPE)A polar phase with slight hydrophobic selectivity in reversed phase mode and moderate polar selectivity in normal phase mode.<figure class="image"><img style="aspect-ratio:500/150;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_cn_769c96c476.webp" alt="Phenomenex: Strata-CN" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_cn_769c96c476.webp 245w," sizes="100vw" width="500" height="150"></figure><ul><li>Surface Area (m²/g): -</li><li>Separation Mode: Normal Phase</li><li>Particle Size: 55</li><li>Recommended Use: Extraction of polar compounds such as those that contain hydroxyl groups.</li></ul><h4>Starting Method</h4><ul><li>Condition: IPA/DCM</li><li>Equilibrate: Hexane</li><li>Load: Pretreated sample</li><li>Wash: 5 % DCM in Hexane</li><li>Elute: 1:1 Hexane / DCM or 1:1 Hexane / IPA</li></ul>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.

Phenomenex Strata Silica (Si-1) Solid Phase Extraction (SPE)

Strata Silica (Si-1) is a normal phase SPE sorbent with unbonded silica particle that offers strong polar selectivity.

Normal Phase Solid Phase Extraction (SPE)A polar phase with slight hydrophobic selectivity in reversed phase mode and moderate polar selectivity in normal phase mode.<figure class="image"><img style="aspect-ratio:500/150;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_si_e4eb885006.webp" alt="Phenomenex: Strata-Silica (Si-1)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_si_e4eb885006.webp 245w," sizes="100vw" width="500" height="150"></figure><ul><li>Surface Area (m²/g): 550, m²/g, null m²/g, 490 m²/g</li><li>Separation Mode: Normal Phase</li><li>Pore Size: 70</li><li>Particle Size: 55</li><li>Recommended Use: Extraction of polar compounds that are similar in structure</li></ul><h4>Starting Method</h4><h5>Strata Normal Phase Method</h5><ul><li>Condition: IPA/DCM</li><li>Equilibrate: Hexane</li><li>Load: Pretreated sample</li><li>Wash: 5 % DCM in Hexane</li><li>Elute: 1:1 Hexane / DCM or 1:1 Hexane / IPA</li></ul>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.

Phenomenex Strata Melamine Solid Phase Extraction (SPE)

A proprietary phase that allows for the simultaneous extraction of melamine and cyanuric acid out of food and biological samples.

Specialty Solid Phase Extraction (SPE) SorbentA proprietary phase that allows for the simultaneous extraction of melamine and cyanuric acid out of food and biological samples.

Phenomenex Strata SCX Solid Phase Extraction (SPE)

A benzene sulfonic acid group is bonded to the surface of the silica particle, giving strong cation-exchange selectivity.

Ion-Exchange Solid Phase Extraction (SPE) SorbentA benzene sulfonic acid group is bonded to the surface of the silica particle, giving strong cation-exchange selectivity.<ul><li>Extraction of 1 °, 2 °, and 3 amines</li></ul><figure class="image"><img style="aspect-ratio:791/384;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_SCX_SPE_f35df1035c.jpg" alt="Phenomenex: Strata SCX" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_SCX_SPE_f35df1035c.jpg 245w," sizes="100vw" width="791" height="384"></figure><ul><li>Surface Area (m²/g): -</li><li>Separation Mode: Ion Exchange</li><li>Particle Size: 55</li><li>Recommended Use: Extraction of weakly basic compounds</li></ul><h4>Starting Method</h4><h5>Strata SCX – Strong Cation-Exchange</h5><ul><li>Condition: 1 mL Methanol</li><li>Equilibrate: 1 mL Acidified Water</li><li>Load: Pretreated sample (acidified)</li><li>Wash 1: 1 mL 0.1N HCl in Water</li><li>Wash 2: 1 mL 0.1N HCl in Methanol, dry under vacuum for 2-5 min</li><li>Elute: 1 mL 5 % NH4OH in Methanol</li></ul>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.

Phenomenex Strata NH2 Solid Phase Extraction (SPE)

This amino phase offers strong polar selectivity and hydrogen bonding under normal phase conditions or can be used as a weak anion-exchange sorbent.

Normal Phase Solid Phase Extraction (SPE)This amino phase offers strong polar selectivity and hydrogen bonding under normal phase conditions or can be used as a weak anion-exchange sorbent.<figure class="image"><img style="aspect-ratio:500/150;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_nh2_a7c3599f55.webp" alt="Phenomenex: Strata-NH2" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_nh2_a7c3599f55.webp 245w," sizes="100vw" width="500" height="150"></figure><ul><li>Surface Area (m²/g): -</li><li>Separation Mode: Normal Phase</li><li>Pore Size: 100</li><li>Particle Size: 25, 55</li><li>Recommended Use: Strong polar selectivity and hydrogen bonding under normal phase conditions or can be used as a weak anion-exchange sorbent</li></ul><h4>Starting Method</h4><h5>Strata NH2 – Weak Anion-Exchange</h5><ul><li>Condition: 1 mL Methanol</li><li>Equilibrate: 1 mL Water, pH 6-7</li><li>Load: Pretreated sample, pH 6-7</li><li>Wash 1: 1 mL 25mM Ammonium Acetate Buffer, pH 6-7</li><li>Wash 2: 1 mL Methanol, dry under vacuum for 2-5 min</li><li>Elute Any Acid: 1 mL 5% NH4OH in Methanol</li><li>Elute Weak Acids: 1 mL 5% Formic Acid in Methanol</li></ul>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.

Phenomenex Strata SAX Solid Phase Extraction (SPE)

The quaternary amine group on this sorbent remains positively charged under all conditions, giving a strong anion-exchange mechanism of retention.

Ion-Exchange Solid Phase Extraction Sorbent (SPE)The quaternary amine group on this sorbent remains positively charged under all conditions, giving a strong anion-exchange mechanism of retention.<figure class="image"><img style="aspect-ratio:500/150;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_sax_470d923b27.webp" alt="Phenomenex: Strata-SAX" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_sax_470d923b27.webp 245w," sizes="100vw" width="500" height="150"></figure><ul><li>Surface Area (m²/g): -</li><li>Separation Mode: Ion Exchange</li><li>Particle Size: 55</li><li>Recommended Use: Extraction of weakly acidic compounds</li></ul><h4>Starting Method</h4><h5>Strata SAX – Strong Anion-Exchange</h5><ul><li>Condition: 1 mL Methanol</li><li>Equilibrate: 1 mL DI Water</li><li>Load: Pretreated sample, pH 6-7</li><li>Wash 1: 1 mL 25mM Ammonium Acetate Buffer, pH 6-7</li><li>Wash 2: 1 mL Methanol, dry under vacuum for 2-5 min</li><li>Elute: 1 mL 5% Formic Acid in Methanol</li></ul>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.

Phenomenex Strata Screen-A Solid Phase Extraction (SPE)

Incorporates the hydrophobic selectivity of a C8 phase and strong anion-exchange for the extraction of acidic drugs from biological matrices.

Mixed-Mode Solid Phase Extraction (SPE) SorbentIncorporates the hydrophobic selectivity of a C8 phase and strong anion-exchange for the extraction of acidic drugs from biological matrices.<figure class="image"><img style="aspect-ratio:500/150;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_Screen_A_f370bdfd48.webp" alt="Phenomenex: Strata Screen-A" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_Screen_A_f370bdfd48.webp 245w," sizes="100vw" width="500" height="150"></figure><ul><li>Surface Area (m²/g): -</li><li>Separation Mode: Multi-Mode</li><li>Particle Size: 55</li><li>Recommended Use: Extracts acidic drugs from biological matrices</li></ul><h4>Starting Method</h4><h5>Strata Screen-A Strong Anion-Exchange</h5><ul><li>Condition: 1 mL Methanol</li><li>Equilibrate: 1 mL Water</li><li>Load: Pretreated sample</li><li>Wash 1: 1 mL 25mM Ammonium Acetate Buffer, pH 6-7</li><li>Wash 2: 1 mL Methanol, dry under vacuum for 2-5 min</li><li>Elute: 1 mL 5% Formic Acid in Methanol</li></ul>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.

Phenomenex Strata Screen-C Solid Phase Extraction (SPE)

Incorporates the hydrophobic selectivity of a C8 phase and strong cation exchange for the extraction of basic drugs from biological matrices.

Strong Cation-Exchange Solid Phase Extraction (SPE)Incorporates the hydrophobic selectivity of a C8 phase and strong cation exchange for the extraction of basic drugs from biological matrices.<figure class="image"><img style="aspect-ratio:500/150;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_Screen_C_b60bb2b7e4.webp" alt="Phenomenex: Strata Screen-C" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_Screen_C_b60bb2b7e4.webp 245w," sizes="100vw" width="500" height="150"></figure><ul><li>Surface Area (m²/g): 500, m²/g, 500 m²/g</li><li>Separation Mode: Multi-Mode</li><li>Pore Size: 70</li><li>Particle Size: 55</li><li>Recommended Use: Extraction of basic drugs from biological matrixes</li></ul><h4>Starting Method</h4><h5>Strata Screen-C Strong Cation-Exchange</h5><ul><li>Condition: 1 mL Methanol</li><li>Equilibrate: 1 mL Acidified Water</li><li>Load: Pretreated sample (acidified)</li><li>Wash 1: 1 mL 0.1N HCl in Water</li><li>Wash 2: 1 mL 0.1N HCl in Methanol, dry under vacuum for 2-5 min</li><li>Elute: 1 mL 5 % NH4OH in Methanol</li></ul>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.

Phenomenex Strata Screen-C GF Solid Phase Extraction (SPE)

Optimized for gravity flow, this sorbent offers hydrophobic selectivity from a C8 phase and strong cation-exchange properties for the extraction of basic drugs.

Strong Cation-Exchange Solid Phase Extraction (SPE)Optimized for gravity flow, this sorbent offers hydrophobic selectivity from a C8 phase and strong cation-exchange properties for the extraction of basic drugs from biological matrixes. Offers the selectivity of Screen-C in a gravity flow particle size for viscous samples.<h4>Starting Method</h4><h5>Strata Screen-C GF Strong Cation-Exchange</h5><ul><li>Condition: 1 mL Methanol</li><li>Equilibrate: 1 mL Acidified Water</li><li>Load: Pretreated sample (acidified)</li><li>Wash 1: 1 mL 0.1N HCl in Water</li><li>Wash 2: 1 mL 0.1N HCl in Methanol, dry under vacuum for 2-5 min</li><li>Elute: 1 mL 5 % NH4OH in Methanol</li></ul>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.

Phenomenex Zebron ZB-1HT Inferno GC Columns

Zebron Inferno column ZB-1HT provides true boiling point separation for hydrocarbon distillation methods.

<h4>Robust Results Up to 430 ºC</h4><ul><li>First non-metal columns stable to 430 °C</li><li>Provides true boiling point separation for hydrocarbon distillation methods</li><li>Longer lifetime with rugged high temperature, polyimide coated, fused silica tubing</li><li>Low activity, provides good peak shape for acidic and basic samples</li><li>Provides robust column performance for high temperature bake outs</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_zb_1ht_3c54563ddc.webp" alt="Phenomenex: Zebron-ZB-1HT" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_zb_1ht_3c54563ddc.webp 245w," sizes="100vw" width="500" height="150"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1_HT_Inferno_54cd995dba.jpg" alt="Phenomenex: Zebron™ ZB-1HT Inferno™" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1_HT_Inferno_54cd995dba.jpg 173w," sizes="100vw" width="651" height="587"><h4>Recommended Use</h4>Rugged, high-temperature stability (up to 430 °C) for:<ul><li>non-polar compounds</li><li>for high boilers</li><li>contaminants</li><li>carry-overs</li><li>high-temp bakeouts</li></ul><h4>Recommended Applications</h4><ul><li>High Boiling Petroleum Products</li><li>Simulated Distillation Methods</li><li>Long-Chained Hydrocarbons</li><li>High Molecular Weight Waxes</li><li>Polymers/Plastics</li><li>Motor Oils</li><li>Diesel Fuel</li></ul><h5>Alternative To: Any 100 % Dimethylpolysiloxane Phase:</h5><ul><li>DB®-1ht</li><li>Rxi®-1HT</li><li>Petrocol 2887</li><li>CP-SimDist</li></ul><h3>Phenomenex Zebron Inferno GC Columns</h3><h4>Overcome Traditional Obstacles</h4><h5>Challenge # 1: Short Fused Silica Column Lifetimes</h5>Unlike Zebron™ Inferno™ GC columns, traditional fused silica columns are not equipped to handle prolonged exposure to temperatures above 360 °C. At high temperatures, fused silica GC columns:<ul><li>Become inflexible and brittle</li><li>Break easily and cause costly replacement</li><li>Require more system downtime for maintenance</li><li>Can’t separate high molecular weight compounds</li></ul><h5>Challenge # 2: Cumbersome Metal Column Tubing</h5>Though metal columns have higher temperature limits than capillary columns, they are more difficult to use.Most metal columns:<ul><li>Are inflexible and hard to use</li><li>Require special tubing cutters for installation</li><li>Are prone to leaks from expansion and contraction</li><li>Have active surfaces, giving poor peak shapes for acids and bases</li><li>Are incompatible with MS detectors</li></ul><h3>How it works</h3>Zebron™ Inferno™ columns offer enhanced performance where other columns fail. The two critical factors that allow for this are:<ul><li><h5>Advanced ESC™ Bonding Technology</h5></li></ul>At high temperature ranges, the stability of standard GC columns deteriorates, resulting in increased bleed. Zebron’s Engineered Self Cross-linking™ (ESC) bonding technology reinforces the stationary phase for enhanced column durability and extremely low bleed levels at high temperatures. The result: Inferno columns with the flexibility to perform for high temp oven ramps and bakeouts.<ul><li>High Temperature Polyimide Coating</li></ul>Standard polyimide resin pyrolyzes at temperatures above 360 °C, making the tubing unstable. Zebron Inferno columns use a temperature resistant polyimide resin that shows minimal thermal degradation, even at temperatures up to 430 °C*. This means longer column lifetime at elevated temperatures.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg" alt="Phenomenex: Zebron Inferno GC Columns - How it works" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg 245w," sizes="100vw" width="978" height="564"><h3>Features of Zebron Inferno GC Columns</h3><h4>Extremely Low Bleed for Rugged Performance</h4><ul><li>Longer column lifetime</li><li>Better reproducibility</li><li>Maximum sensitivity</li><li>More accurate quantitation</li></ul><h4>Increased Column Lifetime with Enhanced Durability</h4><ul><li>Less instrument downtime</li><li>More productivity</li><li>Lower laboratory costs</li></ul><h5>Standard GC Columns Cannot Withstand High Temperature</h5>After prolonged exposure to temperatures above 360 °C, most traditional GC columns become brittle and inflexible, often spontaneously breaking in the middle of a run. Work is stopped in order to change out the column and perform system maintenance. Unlike these fragile columns, ZebronTM InfernoTM columns have a thermally resistant polyimide coating for longer column lifetime at temperatures up to 430 °C. As a result, you get less instrument downtime, and higher productivity.<h4>Greater Performance for High Boiling Compounds</h4><ul><li>Better peak shape</li><li>Improved separation</li><li>More analytes detected</li></ul>Zebron™ Inferno™ columns have the inertness and temperature stability needed to separate high molecular weight compounds. These high boilers require a thermally rugged column with low bleed levels. Inferno columns provide optimal separation of these analytes.

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