<p><strong>Join us for a free two-day LECO Separation Science Workshop on September 23–24, 2026, at the </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/219"><strong>C³AL Laboratory</strong></a><strong> at Cal State LA. Registration is free, and meals and refreshments will be provided throughout the workshop.&nbsp;</strong></p><h4><strong>Registration</strong></h4><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://forms.cloud.microsoft/pages/responsepage.aspx?id=iYeNbqIuykW7qZP4_jUEVbznDB40eK1PgjPzhHyb__9URTFTTFA5UEEzQ1A4MUtFV0o4TEJTNlZCOS4u&amp;route=shorturl"><strong>Register HERE</strong></a></p><p class="cke-user_style-important"><strong>Space is limited, register today!</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg" alt="LECO: LECO Separation Science Workshop - QR code for registration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg 156w," sizes="100vw" width="437" height="437"></p></blockquote><h4><strong>Hand-on Experience with the LECO Complex Chemical Composition Analysis Lab C<sup>3</sup>AL</strong></h4><ul><li>Work directly with LECO instruments in the C<sup>3</sup>AL Laboratory</li><li>Learn complete analytical workflows from sample to answer</li><li>Get expert guidance from LECO application scientists</li><li>Develop methods and solve real-world challenges</li><li>Collaborate, ask questions, and build your skills</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg" alt="Cal State LA: The LECO Pegasus BTX system in Cal State LA’s LECO Complex Chemical Compositional Analysis Lab enhances research and student training in advanced chemical analysis" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg 227w," sizes="100vw" width="1252" height="863"></p><p>The first day will focus on the <strong>fundamentals and theory</strong> of comprehensive two-dimensional gas chromatography (<strong>GC×GC</strong>), with an emphasis on understanding how GC×GC can enhance your research, solve complex analytical challenges, and support your laboratory or company goals.&nbsp;</p><p>The second day will be dedicated to <strong>hands-on activities</strong>, giving participants the opportunity to work directly with <strong>LECO instrumentation</strong>, learn <strong>practical analytical workflows</strong>, and <strong>analyze their own samples</strong> with guidance from LECO application scientists.&nbsp;</p><p>Whether you are new to GC×GC or looking to expand its use in your research or organization, this workshop offers a unique opportunity to learn, explore, and apply the technology in a practical setting. Space is limited, so register early!</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg" alt="Cal State LA: LECO QUADJET GCxGC coupled to Pegasus BT 4D TOM MS in the Complex Chemical Composition Analysis Lab (C³AL)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/thumbnail_Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg 234w," sizes="100vw" width="1949" height="1299"></p>

LECO Separation Science Workshop

<p><strong>Gas chromatography (GC) is a widely used analytical technique across industries for separating and analyzing complex mixtures. Even with premium equipment and optimized methods, analytical problems can emerge. Many laboratories encounter issues such as peak tailing, resolution loss, or signal degradation without a systematic approach for diagnosing them. These problems frequently originate from a critical component: the GC column.</strong></p><p>Proper column maintenance and troubleshooting skills are essential for ensuring accurate data and consistent analytical runs. GC troubleshooting guide provides actionable solutions to common gas chromatography problems, serving as a comprehensive resource to help minimize downtime and maintain analytical quality.</p><h3><strong>Common GC Column Issues and What They Mean?</strong></h3><p>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products?category=7&amp;manufacturerItems=50"><strong>GC column</strong></a> plays a central role in chromatographic separation. When the column issues arise, data integrity is often compromised. Understanding the common problems is the first step in effective troubleshooting in gas chromatography.</p><h4><strong>Peak Tailing</strong></h4><p>Peak tailing occurs when chromatographic peaks lose symmetry and gradually extend toward the baseline. This phenomenon typically arises due to:</p><ul><li>Active sites within the system (residual silanol groups)</li><li>Insufficiently deactivated inlet liners</li><li>Column overloading</li></ul><p>Tailing hinders quantitation accuracy and reduces separation efficiency between closely eluting analytes. Remedial steps include trimming the column inlet, replacing liners, or adjusting the sample load.</p><h4><strong>Loss of Resolution</strong></h4><p>Poor separation between adjacent peaks, often resulting in partial or complete peak overlap, indicates resolution loss. Common causes include:</p><ul><li>Column aging</li><li>Suboptimal temperature programming</li><li>Inadequate carrier gas flow rates</li></ul><p>When resolution decreases, reliable analyte identification becomes challenging. Adjustments to temperature gradient and carrier gas pressure may help restore performance; if improvements are not observed, trimming or replacing the column may be necessary.</p><h4><strong>Ghost Peaks</strong></h4><p>Ghost peaks are unexpected signals that appear even during blank injections. These anomalies typically result from system contamination, septum bleed, or sample carryover from previous analyses. They can compromise data integrity and mask true analyte peaks.</p><p>Effective mitigation includes replacing the septum, thoroughly cleaning or replacing inlet liners, and confirming solvent purity. A clean system should yield no peaks during a blank run.</p><h4><strong>Baseline Noise or Drift</strong></h4><p>Unstable baselines can obscure low-level signals and reduce signal-to-noise ratios.</p><ul><li>Potential causes include detector instability, leaks, or the use of impure carrier gases.</li></ul><p>Resolution involves leak detection, maintenance or replacement of detector components, and ensuring the use of ultra-high purity gases equipped with appropriate moisture and hydrocarbon traps.</p><h4><strong>Decreased Sensitivity</strong></h4><p>Diminished detector response, particularly for trace-level analytes, indicates sensitivity issues. This issue often stems from inlet contamination, detector fouling, or degradation of the column. Maintenance actions should include cleaning or replacing the inlet liner, inspecting the detector, and running a performance test mix.</p><h4><strong>Retention Time Shifts</strong></h4><p>Inconsistent elution times lead to unreliable analyte identification. Shifts can result from unstable oven temperatures, fluctuations in carrier gas flow, or pressure inconsistencies.</p><p>Troubleshooting involves verifying temperature program stability, inspecting leaks and confirming flow rates with a calibrated flow meter. These issues are widely recognized in chromatographic literature and underscore the importance of proactive monitoring and maintenance to uphold system performance and data quality.</p><h4><strong>A Step-by-Step GC Troubleshooting Guide</strong></h4><p>The following troubleshooting process can reduce both time and unnecessary expenses. The five-step guide below outlines a systematic approach to isolating and resolving common gas chromatography issues.</p><h4><strong>Step 1: Evaluate Recent Methods or Hardware Modifications</strong></h4><p>Operational issues frequently follow changes in method parameters or instrument configuration. Alterations such as switching columns, adjusting injection conditions, or modifying the temperature program can introduce new variables.</p><p>Recommended action: Review recent updates to the method or instrument setup. Reverting to a previous configuration may quickly resolve the problem.</p><h4><strong>Step 2: Examine the Inlet and Detector Conditions</strong></h4><p>Contamination is a leading cause of chromatographic anomalies. Accumulation of particles from degraded septa, residues in inlet liners, or buildup within the detector can negatively impact peak shape and baseline stability.</p><p>Recommended action: Inspect the septum, inlet liner, and detector for contamination or wear. Perform routine cleaning and replace parts as needed to maintain system integrity.</p><h4><strong>Step 3: Inspect Column Installation and Physical Condition</strong></h4><p>Incorrect column installation may result in leaks or dead volume, while non-volatile materials often accumulate at the inlet end over time.</p><p>Recommended action: Check both ends of the column for signs of discoloration or damage. Trim 10–30 cm from the inlet if residue is visible and confirm that the column is installed at the proper depth and without mechanical strain.</p><h4><strong>Step 4: Perform ank Run or Analyze a Standard Test Mix</strong></h4><p>Diagnostic runs are valuable for identifying contamination and assessing column performance. Blank injections can reveal ghost peaks, while standard test mixtures provide insight into resolution, retention time accuracy, and peak symmetry.</p><p>Recommended action: Compare test results to the column’s original quality control report to detect performance degradation.</p><h4><strong>Step 5: Replace Suspected Faulty Components</strong></h4><p>If previous steps do not resolve the issue, begin systematically replacing components, starting with consumables.</p><p>Recommended action: Replace low-cost parts such as septa, liners, or O-rings before considering column or detector replacement. A logical, stepwise replacement approach ensures efficiency and prevents the unnecessary disposal of functional components.</p><p>By following these GC troubleshooting guides, common sources of error in gas chromatography can be isolated more effectively, leading to quicker resolutions and sustained instrument performance.</p><h3><strong>Preventive Maintenance Tips for GC Columns</strong></h3><p>Implementing routine maintenance procedures is essential for preserving the performance of gas chromatography (GC) systems and extending the operational lifespan of GC columns. The following best practices serve as foundational elements in effective column care.</p><h4><strong>Ensure Proper Column Storage</strong></h4><p>Columns not in active use should be stored with both ends securely capped to prevent contamination. Storage conditions must be clean, dry, and temperature controlled. Exposure to ambient moisture or air can lead to degradation of the stationary phase and compromise column longevity.</p><h4><strong>Utilize Guard Columns and Inlet Liners</strong></h4><p>Guard columns act as protective barriers, intercepting contaminants before they reach the analytical column. Similarly, inlet liners help to trap particulates and prevent the buildup of non-volatile sample residues within the system.</p><p>Regular replacement of guard columns and liners is recommended, especially when analyzing complex or heavily matrix-laden samples.</p><h4><strong>Perform Periodic Trimming</strong></h4><p>The column’s inlet end is most prone to contamination from sample residues and non-volatile materials. Routine trimming of a few centimeters can significantly restore performance and improve peak quality.</p><h4><strong>Conduct Regular Leak Checks and Replace Septa</strong></h4><p>Leaks can introduce oxygen and moisture—both of which are detrimental to column health. Routine leak detection using appropriate tools is advised, along with scheduled septa replacement.</p><p>Signs such as discoloration, cracking, or deformation of the septum after repeated injections indicate that replacement is due.</p><h4><strong>Use Clean Carrier Gas</strong></h4><p>The purity of the carrier gas plays a crucial role in protecting both the column and detector. It is imperative to use ultra-high purity gases equipped with moisture and hydrocarbon traps to prevent contamination.</p><p>Research, including work by Grob and Barry (2004), has demonstrated that gas cleanliness is especially important in trace-level and GC-MS applications, where even minor impurities can lead to significant analytical errors.</p><p>By following these preventive maintenance strategies, GC users can maintain stable performance, reduce unplanned downtime, and ensure consistent data quality across analyses.</p><h3><strong>When to Replace your GC Column</strong></h3><p>Recognizing the end of a GC column’s life is essential for maintaining data quality and system reliability. Performance trends often indicate when a column is near failure. Common signs include persistent peak tailing or broadening - even after trimming - along with inconsistent or shifting retention times.</p><p>A noticeable increase in baseline noise or bleed, reduced resolution despite maintenance, and recurring ghost peaks or unstable baselines are all indicators that the column is no longer performing optimally.</p><p>Physically, discoloration or damage to the inlet end of the column suggests contamination buildup, often caused by dirty samples or reactive compounds. While trimming can temporarily restore performance, repeated issues signal that full replacement is likely needed.</p><p>When selecting a new column, it is important to match the specifications - stationary phase, length, internal diameter, and film thickness - to maintain consistency. High-quality options like Zebron GC columns from Phenomenex offer reliable durability and performance across a wide range of applications, supported by comprehensive <a target="_blank" rel="noopener noreferrer" href="https://www.phenomenex.com/techniques/improved-performance">Zebron GC troubleshooting resources</a> to help users optimize their results and resolve issues quickly.</p>

GC Columns - Troubleshooting & Maintenance

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 24th August 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you application notes by <strong>Shimadzu, Thermo Fisher Scientific </strong>and <strong>Waters Corporation </strong>and poster by<strong> MDCW / GC Image!</strong></p><h3><strong>1. MDCW / GC Image: Alignment and Filtering Tools for Enhanced Differencing of Two-Dimensional Chromatograms</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/P_21_Wu_3838638ea4.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><h5><strong>Challenges&nbsp;</strong></h5><p>Chromatogram-like visual differencing is intuitive, yet simple pixel-to-pixel subtraction often produces noisy artifacts, fails to correct retention-time shifts, and can obscure low-intensity but meaningful differences.&nbsp;</p><p>Previously, we developed comparative visualization methods [1] based on classic image-comparison techniques, including:&nbsp;</p><ul><li>Alignment with specialized color maps to visually highlight discrepancies between chromatograms&nbsp;</li><li>Interactive matching across two chromatograms [2], enabling both qualitative and quantitative side-by-side assessment at the individual-peak level&nbsp;</li></ul><p>We extend this work by presenting a more robust chromatogram differencing visualization method designed to overcome these limitations</p><h4><strong>Example 1: Alignment for Data Fusion (FID vs MS)&nbsp;</strong></h4><ul><li><strong>Data Set:</strong> GCxGC data of a diesel fuel sample&nbsp;</li><li><strong>Instruments:</strong> <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=10&amp;search=7890A"><strong>Agilent 7890A GC</strong></a>/InfoMass L10 thermal modulator/Hexin TOFMS<ul><li><strong>Detectors:</strong> FID (350 C, 200 Hz), MS (45-450 m/z, 50 Hz)&nbsp;</li><li><strong>Modulation:</strong> 6 seconds with programmable cold jet gas flow (15L/min to 6 L/min)</li></ul></li></ul><h4><strong>Example 2: Differencing (GC×GC-MS)&nbsp;</strong></h4><ul><li><strong>Data Set: </strong>GCxGC-TOFMS data set of different dark chocolates [3].</li><li><strong>Instruments: </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=23&amp;search=AccuTof"><strong>JEOL AccuTof GC mass spectrometer</strong></a> with an <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=10&amp;search=7890"><strong>Agilent 7890 GC</strong></a></li></ul><h4><strong>Example 3: Differencing with BPC (LC×LC-MS)&nbsp;</strong></h4><ul><li><strong>Data Set:</strong> LCxLC-MS data of different types of beer [4].&nbsp;</li><li><strong>Instruments: </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/lcms/library?mainauthorItems=10&amp;search=1290+infinity+2D-LC"><strong>Agilent 1290 Infinity 2D-LC</strong></a> solution coupled with an <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/lcms/library?mainauthorItems=10&amp;search=6530"><strong>Agilent 6530 Accurate-Mass Q-TOF LC/MS system</strong></a></li></ul><h3><strong>2. Shimadzu: Comprehensive and High-Sensitivity Analysis of Food Aroma by Simultaneous Scan/MRM Measurement Using Triple Quadrupole GC-MS/MS</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_01_01269_en_657ee319e0.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>User benefits</strong></h4><ul><li>Simultaneous scan/MRM measurement enables comprehensive search by scan measurement and high-sensitivity analysis of trace aroma compounds by MRM in a single measurement.&nbsp;</li><li>With LabSolutions Insight Explore GCMS, deconvolution analysis of scan data and target analysis of MRM data are possible in a single software program.&nbsp;</li><li>The Multi-Mode Injection Unit (MMI), which allows rapid heating, supports aroma analysis in the thermal desorption (TD) mode</li></ul><p>The “aroma” of food products and beverages is a key factor that largely determines product quality and consumer preferences, and thus is an extremely important element in product development and quality control. Since the gas chromatograph mass spectrometer (GC-MS) provides excellent performance in qualitative analysis of volatile compounds, it is used to measure various aroma components that make up an odor. However, due to the diversity of aroma compounds and their wide concentration range, which extends from the ppm to the ppt order, an analytical method that allows efficient measurement of these substances is demanded.&nbsp;</p><p>Non-targeted analysis by scan measurement is an effective tool for comprehensive profiling, but in many cases, it is difficult to identify the trace components that make a significant contribution to aroma due to the limits of instrument sensitivity and matrix interference. On the other hand, although widetarget analysis by the MRM (Multiple Reaction Monitoring) mode using GC-MS/MS offers high sensitivity and selectivity for several hundred target components, MRM lacks a search capability for unknown components.</p><p>Therefore, this Application News article reports a technique that satisfies both comprehensive non-targeted search and highsensitivity detection of trace components in a single analysis by combining the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=1&amp;search=8040+RX"><strong>GCMS-TQ 8040 RX</strong></a>, which supports simultaneous data acquisition in simultaneous multi-component analysis measurements by scan measurement and the MRM mode, and the Smart Aroma Database for use in aroma analysis. In addition, in this experiment, the thermal desorption (TD) mode of the Multi-Mode Injection Unit (MMI) was adopted for sample introduction. This enablesintroduction of componentstapped on the adsorbent without using a dedicated TD device, thereby achieving a simplified system configuration.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>This Application News article showed that it is possible to achieve both a comprehensive non-targeted analysis of food aroma and a high-sensitivity wide-target analysis of trace components in a single analysis, without carrying out complicated operations, by simultaneous scan/MRM measurement combining the GCMSTQ8040 RX and the Smart Aroma Database. This article also demonstrated that use of the Multi-Mode Injection Unit (MMI) enables measurements in the thermal desorption (TD) mode without using dedicated TD instrumentation, and also allows a flexible response in case of budgetary or installation space limitations. A comprehensive aroma evaluation based on this approach will facilitate the discovery of important aroma components that were easily overlooked in the past, and is expected to make important contributions to product development and quality control in the food and beverage industries.</p><h3><strong>3. Thermo Fisher Scientific: Implementing EPA OTM-50 for PFAS destruction monitoring by TD-GC-MS/MS</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_004773_gc_td_gc_ms_epa_otm_50_pfas_an04773_na_en_99fd5fc528.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Per- and polyfluoroalkyl substances are used across a broad range of industrial and consumer applications. As PFAS-containing materials are treated or destroyed, incomplete decomposition can generate volatile fluorinated compounds, including short-chain and ultra-volatile species. These volatile compounds are important because they may provide evidence of incomplete mineralization once emitted from stationary sources.</p><p>EPA OTM-50 was developed to provide a consistent approach for collecting and quantitatively analyzing target VFCs from emissions originating from known industrial products with incomplete thermal destruction. The EPA method uses passivated stainlesssteel canisters followed by GC-MS analysis and is applicable to gas samples collected from industrial source ducts, vents, stacks, and related emission points.&nbsp;</p><p>The method is performance-based, allowing laboratories flexibility in GC column selection, GC conditions, and MS conditions, provided that GC-MS remains the basis for separation and quantitation and the required performance criteria are met. This flexibility is important because OTM-50 analytes span a challenging volatility range and may occur in complex matrices containing CO2 , water vapor, acid gases, and other volatile organic compounds.&nbsp;</p><p>Gas chromatography-based approaches are well suited to volatile and neutral fluorinated compounds. Thermal desorption enables preconcentration of trace-level analytes from air samples, improving sensitivity and enabling detection at relevant levels for environmental studies.&nbsp;</p><p>This application note describes implementation of EPA OTM-50 using cryogen-free thermal desorption coupled to triple quadrupole GC-MS/MS. The workflow addresses key analytical challenges: trapping ultra-volatile compounds such as CF4 , managing high levels of CO2 and humidity, achieving sub-ppbv sensitivity, and maintaining repeatable quantitative performance in support of PFAS destruction monitoring.</p><h4><strong>Experimental&nbsp;</strong></h4><h5><strong>Instrument configuration&nbsp;</strong></h5><p>The analytical system consisted of a <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=6&amp;search=UNITY-Kori-CIA"><strong>Markes UNITY</strong></a><strong>-Kori-CIA Advantage HL-xr thermal desorption system</strong> coupled to a <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/485"><strong>TSQ 9610 Triple Quadrupole GC-MS/MS</strong></a> equipped with a <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=3&amp;search=nevervent"><strong>Thermo Scientific™ NeverVent™ AEI Ion Source</strong></a> (Figure 1). The Markes thermal desorber configuration included cryogen-free focusing, controlled canister introduction, and water and CO2 management strategies.</p><h4><strong>Conclusions&nbsp;</strong></h4><p>This work demonstrates implementation of EPA OTM-50 using thermal desorption coupled to triple quadrupole GC-MS/MS for the analysis of volatile fluorinated compounds in air, with solutions helping to solve key analytical challenges for this type of analysis.&nbsp;</p><ul><li><strong>Alignment with EPA OTM-50 scope:</strong> supports canisterbased analysis of VFCs emitted from stationary sources, including compounds associated with incomplete PFAS destruction.&nbsp;</li><li><strong>Cryogen-free preconcentration:</strong> enables practical trapping and transfer of volatile analytes without reliance on liquid cryogens, reducing operational complexity.&nbsp;</li><li><strong>Improved selectivity through MS/MS: </strong>SRM acquisition on the TSQ 9610 Triple Quadrupole GC-MS/MS improves confidence in target identification and quantitation in complex emission matrices.&nbsp;</li><li><strong>Dual-method strategy for broad volatility coverage:</strong> separate sample volumes for CF4 and the remaining VFCs enable analysis across the challenging OTM-50 volatility range.&nbsp;</li><li><strong>CO2 and humidity management:</strong> controlled dilution, selective trap purging, and Kori-xr water management address two of the most significant matrix challenges in stationary source emissions.&nbsp;</li><li><strong>Robust quantitative performance: </strong>calibration across 0.1–100 ppbv (0.125–50 ppbv for CF4 ) showed R2 ≥ 0.998 for reported compounds or &lt; 20% RSD for Average Response Factor, with pptv MDLs and repeatability generally consistent with OTM-50 precision expectations.&nbsp;</li><li><strong>Industrial relevance: </strong>the workflow supports chemical manufacturing, PFAS treatment, and waste management facilities seeking defensible data to evaluate destruction efficiency and identify products of incomplete destruction.&nbsp;</li></ul><p>Overall, the combination of Markes thermal desorption technology with the Thermo Scientific TSQ 9610 Triple Quadrupole GC-MS/MS provides a practical, selective, and robust analytical approach for laboratories implementing EPA OTM-50 for volatile PFAS and VFC monitoring in air.</p><h3><strong>4. Waters Corporation: Analysis of Polybrominated Diphenyl Ether Flame Retardants in Environmental Matrices Using Atmospheric Pressure Chemical Ionization GC-MS/MS</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/720009524_en_58a948f96a.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>Benefits&nbsp;</strong></h4><ul><li>The performance of atmospheric pressure gas chromatography (APGC ™) on Xevo™ TQ Absolute Mass Spectrometer for the analysis of PBDEs is equal-to or better-than traditional analysis using electron impact magnetic sector making it well suited for use in the most challenging regulatory and standard methods.</li><li>The ability of APGC to tolerate high carrier gas flow helps improve method performance for the most challenging members of this class inlcuding BDE 209 which reduces the need for maintenance and reanalysis of samples.</li><li>Operator training is reduced to weeks from months through conversion of the method from a magnetic sector to tandem quadrupole mass spectrometer.</li><li>Use of a single, inexpensive, readily available gas for chromatographic separation, ionization and MS/MS fragmentation provides a simpler, more sustainable system.</li></ul><p>With the 2001 signing of the Stockholm Convention, the stage was set for global harmonization of efforts to monitor for POPs in the environment.1 By 2004, when countries began implementing the convention, measures aimed at reducing or eliminating intentional and unintentional release of POPs into the environment were supported by annexes that defined the different chemical classes of highest interest which included PBDEs. To date, 185 states plus the European Union have joined in this effort which includes requirements for monitoring for POPs in multiple environmental matrices. Because the implications of unintentional or intentional noncompliance may be subject to enforcement action, high confidence data is needed to support surveillance and reporting efforts. Furthermore, high sensitivity analysis is required due to the possibility of steadily increasing trace levels of PBDEs across years of time through transport in the environment that tends to increase concentrations of persistent organic pollutants such as these in cooler Arctic regions of the globe through the grasshopper effect.2 These requirements initially led to the development of gas chromatography electron ionization high resolution magnetic sector based analytical methods. The performance of EI GC-HRMS in the hands of a well-trained operator and a lab with rigorous quality control procedures has proven to provide the sensitivity and specificity required of the forensic data used in legal actions, for compliance reporting and for providing the greatest protection to populations and the environment.&nbsp;</p><p>However, GC-HRMS has several limitations, including extensive education and training requirements, slow acquisition speeds, and significant laboratory space demands. In contrast, more modern techniques such as tandem quadrupole (TQ) mass spectrometry (MS/MS) offer broad improvements in these areas. Additionally, limitations imposed by EI such as frequent source maintenance and shortcomings caused by carrier gases other than helium hamper this time-honored technique. The more recent combination of APCI with TQ has demonstrated promise in overcoming these limitations while providing data of equivalent confidence to EI GCHRMS.&nbsp;</p><p>After having been deployed in many labs, GC-APCI has continued to contribute to the study of PBDEs in multiple matrices and applications. An evaluation of the first generation of GC-APCI MS/MS, analyzing PBDEs in marine and food samples, reported higher response for higher brominated (Br8-10) congeners than GC-EI-HRMS.3 Later work reported GC-APCI MS/MS LODs comparable or better than EI MS/MS for plasma extracts.4 Recent work reported on the use of GC-APCI HRMS (QTof) as part of the continuation of a 20 year study analyzing aquatic organisms to evaluate environmental PBDE trends.5 In this work, 24 PBDEs plus hexabromobiphenyl were analyzed on a XevoTM TQ Absolute Tandem Quadrupole Mass Spectrometer using the APGC ionization source.</p><h4><strong>Experimental</strong></h4><ul><li><strong>GC system: </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=10&amp;search=8890"><strong>8890 (Agilent Technologies, Inc.)&nbsp;</strong></a></li><li><strong>Column: </strong>Rtx®-1614, 15 m x 0.25 mm ID x 0.10 µm film (Restek Corporation)</li><li><strong>MS system: </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/554"><strong>Xevo TQ Absolute Mass Spectrometer</strong></a></li><li><strong>Software: </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1544"><strong>waters_connect™</strong></a> for Quantitation Software</li></ul><h4><strong>Conclusions&nbsp;</strong></h4><p>An all-nitrogen configuration for APGC on Xevo TQ Absolute Mass Spectrometer was successfully applied to the analysis of PBDEs in environmental matrices by adapting a reference method previously used on magnetic sector EI GC-HRMS. All performance criteria were equal-to or better-than those typically achieved by magnetic sector which demonstrates feasibility of GC-APCI MS/MS as an alternative for the most challenging regulatory and standard analytical methods. Furthermore, the change from a vacuum source to the atmospheric ionization source makes the use of high nitrogen carrier gas flow practical which has advantages for operating cost versus helium while achieving similar chromatographic separation and sensitivity. The move to tandem quadrupole mass spectrometry from high resolution mass spectrometry updates the method for improved performance measures such as higher acquisition speeds and high specificity MS/MS while also requiring reduced training time and expertise as compared with magnetic sectors.</p></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 35, 2026

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Thermo Scientific Nicolet Summit LITE FTIR Spectrometer

Compact FTIR spectrometer for routine material identification, QA/QC laboratories, and education. Features LightDrive optics, OMNIC Paradigm software, and easy operation.

<p><strong>The Thermo Scientific™ Nicolet™ Summit™ LITE FTIR Spectrometer is a compact and cost-effective Fourier Transform Infrared (FTIR) spectrometer designed for routine material identification, quality control, incoming goods inspection, and educational laboratories. Combining the proven LightDrive™ Optical Engine with intuitive OMNIC™ Paradigm Software, the system enables users to identify, verify, and characterize materials quickly and confidently.</strong></p><p>Engineered with the same core optical technology used in higher-end Nicolet systems, the Summit LITE delivers reliable <strong>performance, simplified operation, and low ownership costs</strong>. Its compact footprint makes it an ideal solution for multi-user laboratories, QA/QC environments, and teaching facilities where space, efficiency, and ease of use are important.</p><h3><strong>Key Features</strong></h3><ul><li><strong>LightDrive™ Optical Engine</strong> for stable, reliable FTIR performance</li><li><strong>5-year warranty </strong>on the interferometer, laser, and infrared source</li><li><strong>OMNIC™ Paradigm Software </strong>with intuitive dashboard interface</li><li><strong>Smart Background technology</strong> for automatic background collection</li><li><strong>LightBar LED status indicator</strong> with visual pass/fail feedback</li><li>Customizable workflows for routine analytical procedures</li><li><strong>Cloud-enabled connectivity </strong>through OMNIC™ Anywhere</li><li><strong>Built-in spectral library</strong> searching and material identification tools</li><li>Compact, laboratory-friendly footprint</li><li>Optional Everest™ ATR accessory with monolithic diamond crystal</li><li>Designed for QA/QC, teaching, and routine analytical laboratories</li><li>Fast implementation with extensive online help and training resources</li></ul><h3><strong>Software Features</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2456"><strong>OMNIC™ Paradigm Software</strong></a> simplifies FTIR operation for both experienced spectroscopists and routine users.</p><h4><strong>Key software capabilities include:</strong></h4><ul><li>Spectral acquisition and processing</li><li>Multi-component searching</li><li>Spectral library creation and management</li><li>Workflow automation</li><li>Automatic background collection</li><li>Remote data access through cloud connectivity</li><li>Secure data handling and compliance-ready workflows</li><li>Support for regulated laboratory environments</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Beam Splitter:</strong> KBr/Ge mid-infrared optimized</li><li><strong>Optical Components:</strong> LightDrive Optical Engine including source, laser, interferometer, and detector</li><li><strong>Detector Type:</strong> Lithium tantalate (LiTaO₃) detector</li><li><strong>Dimensions (D × W × H):</strong> 32 × 34 × 24 cm (12.7 × 13.3 × 9.6 in.)</li><li><strong>Applications:</strong> Education, Polymers &amp; Plastics, QA/QC, Pharmaceuticals, Forensics, Environmental Analysis</li><li><strong>Compatible Accessories:</strong> Everest™ Diamond ATR, iD™ Accessories (including iD7 ATR), and hundreds of commercially available accessories</li><li><strong>Source Type:</strong> Single-point IR source with non-migrating hotspot for enhanced data reproducibility</li><li><strong>Spectral Range:</strong> 8000–350 cm⁻¹</li><li><strong>Spectral Resolution:</strong> Better than 0.6 cm⁻¹</li><li><strong>Voltage:</strong> 110/240 V</li><li><strong>Warranty:</strong> 5-year warranty on the interferometer, laser, and infrared source</li></ul><h3><strong>Typical Applications</strong></h3><h4><strong>Pharmaceutical Analysis</strong></h4><ul><li>Raw material identification</li><li>Incoming goods inspection</li><li>Verification of pharmaceutical ingredients</li><li>Contaminant identification</li></ul><h4><strong>Polymer Analysis</strong></h4><ul><li>Polymer identification</li><li>Additive verification</li><li>Material degradation studies</li><li>Packaging material quality control</li></ul><h4><strong>Education</strong></h4><ul><li>FTIR teaching laboratories</li><li>Functional group identification</li><li>Student training and practical exercises</li></ul><h4><strong>Battery Materials</strong></h4><ul><li>Electrolyte characterization</li><li>Material verification</li><li>Quality control of battery components</li></ul><h4><strong>Gemology and Mineral Analysis</strong></h4><ul><li>Gemstone identification</li><li>Mineral composition analysis</li><li>Authentication of natural materials</li></ul><h4><strong>Automotive Materials</strong></h4><ul><li>Polymer and composite characterization</li><li>Interior material verification</li><li>Fuel additive analysis</li><li>Failure investigations</li></ul><h4><strong>Lubricants and Oils</strong></h4><ul><li>Condition monitoring</li><li>Lubricant formulation verification</li><li>Contamination detection</li><li>Predictive maintenance programs</li></ul><h3><strong>Benefits</strong></h3><ul><li>Affordable entry into FTIR spectroscopy</li><li>Easy operation for non-expert users</li><li>Compact design for space-limited laboratories</li><li>Reliable daily performance for routine testing</li><li>Low maintenance requirements</li><li>Fast material identification and verification</li><li>Suitable for both educational and industrial laboratories</li></ul><p>The Nicolet Summit LITE FTIR Spectrometer delivers the essential capabilities required for routine FTIR analysis while maintaining the simplicity, reliability, and affordability expected from the Thermo Scientific Nicolet product family.</p>

Thermo Scientific Nicolet Summit X FTIR Spectrometer

High-performance Thermo Scientific Nicolet Summit X FTIR Spectrometer for QA/QC, research, and regulated laboratories. Features LightDrive optics, a DTGS detector, OMNIC Paradigm software, and advanced workflows.

<p><strong>The Thermo Scientific™ Nicolet™ Summit™ X FTIR Spectrometer is a powerful and versatile Fourier Transform Infrared (FTIR) spectrometer designed for laboratories that require enhanced performance, regulatory readiness, and advanced analytical capabilities. Combining the proven LightDrive™ Optical Engine with OMNIC™ Paradigm Software, the Summit X delivers fast, reliable material identification and characterization while simplifying routine and complex analytical workflows.</strong></p><p>Ideal for both single-user and multi-user laboratories, the Summit X provides an excellent balance of performance, flexibility, and ease of use. Its compact footprint, robust construction, and advanced software environment make it suitable for quality control, research, teaching, and regulated laboratory environments. The system is designed to help laboratories improve productivity, streamline workflows, and maintain confidence in analytical results.</p><h3><strong>Key Features</strong></h3><ul><li>LightDrive™ Optical Engine for exceptional FTIR performance and long-term stability</li><li>10-year warranty on the interferometer, laser, and infrared source</li><li>High-performance DTGS detector</li><li>OMNIC™ Paradigm Software with intuitive dashboard interface</li><li>Smart Background technology for automatic background collection</li><li>LightBar LED status indicator with visual pass/fail feedback</li><li>Pharmacopeia-ready workflows for regulated environments</li><li>Drag-and-drop workflow creation and automation</li><li>Cloud-enabled connectivity through Thermo Fisher Connect and OMNIC™ Anywhere</li><li>Multi-component spectral searching and library management</li><li>Optional touchscreen interface for simplified QA/QC operation</li><li>Optional Everest™ ATR accessory with monolithic diamond crystal</li><li>Compact design suitable for busy laboratory environments</li><li>Designed for routine QA/QC, analytical services, and research applications</li><li>5,000 included reference spectra for rapid compound identification</li></ul><h3><strong>Software Features</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2456"><strong>OMNIC™ Paradigm Software </strong></a>provides a modern, workflow-oriented platform that simplifies FTIR analysis for both experienced spectroscopists and routine users.</p><h4><strong>Key software capabilities include:</strong></h4><ul><li>Spectral acquisition and processing</li><li>Multi-component searching</li><li>Spectral library creation and management</li><li>Automated workflow generation</li><li>Drag-and-drop workflow editor</li><li>Smart Background automatic background measurement</li><li>One-click spectral, correlation, and multi-component searching</li><li>Cloud-based data access and collaboration</li><li>AI-assisted spectral interpretation through OMNIC™ Anywhere</li><li>Dashboard-based instrument monitoring and data management</li><li>Support for data integrity and compliance workflows</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Beam Splitter:</strong> KBr/Ge mid-infrared optimized</li><li><strong>Optical Components:</strong> LightDrive™ Optical Engine including source, laser, interferometer, and detector</li><li><strong>Detector Type:</strong> Fast-recovery deuterated triglycine sulfate (DTGS) detector</li><li><strong>Dimensions (D × W × H):</strong> 32 × 34 × 24 cm (12.7 × 13.3 × 9.6 in.)</li><li><strong>Applications:</strong> Quality Control (QA/QC), Forensics, Polymers &amp; Plastics, Pharmaceuticals, Environmental Analysis, Education, Geology and Gemstone Analysis</li><li><strong>Compatible Accessories:</strong> Everest™ Diamond ATR, iD™ Accessories (including iD7 ATR), and hundreds of commercially available accessories</li><li><strong>Source Type:</strong> Single-point IR source with non-migrating hotspot for enhanced data reproducibility</li><li><strong>Spectral Range:</strong> 8000–350 cm⁻¹</li><li><strong>Spectral Resolution:</strong> Better than 0.6 cm⁻¹</li><li><strong>Electrical Requirements:</strong> 100/240 V, 47/63 Hz, 110 W</li><li><strong>Warranty:</strong> 10 years on the interferometer, laser, and infrared source</li></ul><h3><strong>Typical Applications</strong></h3><h4><strong>Pharmaceutical Analysis</strong></h4><ul><li>Raw material verification</li><li>Incoming goods inspection</li><li>Pharmacopeial compliance workflows</li><li>Contaminant identification</li><li>At-line manufacturing support</li></ul><h4><strong>Polymer Analysis</strong></h4><ul><li>Polymer identification</li><li>Additive verification</li><li>Material degradation studies</li><li>Packaging material quality control</li><li>Composite material characterization</li></ul><h4><strong>Education and Academic Research</strong></h4><ul><li>FTIR teaching laboratories</li><li>Functional group identification</li><li>Student training and practical exercises</li><li>Research applications</li></ul><h4><strong>Battery Materials and Components</strong></h4><ul><li>Electrolyte characterization</li><li>Material verification</li><li>Quality control of battery components</li><li>Monitoring material changes affecting battery performance and safety</li></ul><h4><strong>Gemology and Mineral Analysis</strong></h4><ul><li>Gemstone identification</li><li>Mineral composition analysis</li><li>Authentication of treated and untreated gemstones</li></ul><h4><strong>Automotive Materials</strong></h4><ul><li>Polymer and composite characterization</li><li>Interior material verification</li><li>Fuel additive analysis</li><li>Material development and failure investigations</li></ul><h4><strong>Lubricants and Oils</strong></h4><ul><li>Lubricant condition monitoring</li><li>Formulation verification</li><li>Contamination detection</li><li>Predictive maintenance programs</li></ul><h3><strong>Benefits</strong></h3><ul><li>Enhanced performance for demanding QA/QC laboratories</li><li>Long-term reliability supported by a 10-year optical system warranty</li><li>Intuitive software that reduces training requirements</li><li>Streamlined workflows that improve laboratory productivity</li><li>Ready for regulated and compliance-driven environments</li><li>Flexible platform for both routine analysis and advanced applications</li><li>Cloud-enabled collaboration and remote data access</li><li>Compact design with a small laboratory footprint</li></ul><p>The Nicolet Summit X FTIR Spectrometer combines high-performance optics, advanced software, and regulatory-ready workflows in a compact platform designed to meet the needs of modern analytical laboratories. Whether used for quality control, materials characterization, research, or regulated testing, the Summit X delivers the performance, reliability, and productivity expected from the Thermo Scientific™ Nicolet™ product family.</p>

Thermo Scientific Nicolet Summit PRO FTIR Spectrometer

High-performance Thermo Scientific Nicolet Summit PRO FTIR spectrometer for demanding QA/QC, regulated, and research laboratories. Features touchscreen operation, high spectral resolution, and OMNIC Paradigm software.

<p><strong>The Thermo Scientific™ Nicolet™ Summit™ PRO FTIR Spectrometer is the most advanced model in the Nicolet Summit family, combining high-performance optics, superior spectral resolution, and an integrated touchscreen interface in a compact and versatile platform. Designed for demanding QA/QC laboratories, analytical service laboratories, regulated environments, and research applications, the Summit PRO delivers fast, reliable material identification and characterization while simplifying routine and advanced workflows.</strong></p><p>Powered by the proven LightDrive™ Optical Engine and OMNIC™ Paradigm Software, the Summit PRO offers outstanding performance, intuitive operation, and advanced compliance capabilities. Its integrated touchscreen interface and built-in workflow tools help laboratories improve productivity, streamline data acquisition, and maintain confidence in analytical results.</p><h3><strong>Key Features</strong></h3><ul><li>LightDrive™ Optical Engine for exceptional FTIR performance and long-term stability</li><li>High-resolution performance with spectral resolution better than 0.45 cm⁻¹</li><li>Thermoelectrically cooled (TEC) DTGS detector for maximum detector response linearity</li><li>10-year warranty on the interferometer, laser, and infrared source</li><li>Integrated touchscreen interface for simplified QA/QC workflows</li><li>OMNIC™ Paradigm Software with touchscreen, operator, and desktop operating modes</li><li>Smart Background technology for automatic background collection</li><li>LightBar LED status indicator with visual pass/fail feedback</li><li>Pharmacopeia-ready workflows for regulated environments</li><li>Drag-and-drop workflow creation and automation</li><li>Cloud-enabled connectivity through Thermo Fisher Connect and OMNIC™ Anywhere</li><li>AI-assisted spectral interpretation through OMNIC™ Anywhere</li><li>Multi-component spectral searching and library management</li><li>Everest™ ATR accessory with monolithic diamond crystal available</li><li>5,000 included reference spectra for rapid compound identification</li><li>Compact footprint suitable for both routine and research laboratories</li></ul><h3><strong>Software Features</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2456"><strong>OMNIC™ Paradigm Software</strong></a><strong> </strong>provides a modern, workflow-oriented platform that simplifies FTIR analysis for both experienced spectroscopists and routine users.</p><h4><strong>Key software capabilities include:</strong></h4><ul><li>Spectral acquisition and processing</li><li>Multi-component searching</li><li>Spectral library creation and management</li><li>Automated workflow generation</li><li>Drag-and-drop workflow editor</li><li>Smart Background automatic background measurement</li><li>One-click spectral, correlation, and multi-component searching</li><li>Cloud-based data access and collaboration</li><li>AI-assisted spectral interpretation through OMNIC™ Anywhere</li><li>Dashboard-based instrument monitoring and data management</li><li>Support for data integrity and compliance workflows</li><li>Touchscreen, Operator, and Desktop operating modes</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Beam Splitter:</strong> KBr/Ge mid-infrared optimized</li><li><strong>Optical Components:</strong> LightDrive™ Optical Engine including source, laser, interferometer, and detector</li><li><strong>Detector Type:</strong> Thermoelectrically cooled (TEC) DTGS detector for maximum detector response linearity</li><li><strong>Dimensions (D × W × H):</strong>&nbsp;<ul><li><strong>Spectrometer: </strong>32 × 34 × 24 cm (12.7 × 13.3 × 9.6 in.)</li><li><strong>Spectrometer with touchscreen:</strong> 32 × 53 × 43 cm (12.0 × 20.8 × 17.0 in.)</li></ul></li><li><strong>Applications:</strong> Polymers &amp; Plastics, QA/QC, Pharmaceuticals, Education, Forensics, Geology and Gemstone Analysis, Automotive Materials, Environmental Analysis</li><li><strong>Compatible Accessories:</strong> Everest™ Diamond ATR, iD™ Accessories (including iD7 ATR), and hundreds of commercially available accessories</li><li><strong>Source Type:</strong> Single-point IR source with non-migrating hotspot for unmatched data reproducibility</li><li><strong>Spectral Range:</strong> 8000–350 cm⁻¹</li><li><strong>Spectral Resolution:</strong> Better than 0.45 cm⁻¹</li><li><strong>Electrical Requirements:</strong> 100/240 V, 47/63 Hz, 110 W</li><li><strong>Weight:</strong><ul><li><strong>Spectrometer: </strong>10.9 kg (24 lb)</li><li><strong>Spectrometer with touchscreen:</strong> 12.6 kg (29 lb)</li></ul></li><li><strong>Warranty:</strong> 10 years on the interferometer, laser, and infrared source</li></ul><h3><strong>Typical Applications</strong></h3><h4><strong>Pharmaceutical Analysis</strong></h4><ul><li>Raw material verification</li><li>Incoming goods inspection</li><li>Pharmacopeial compliance workflows</li><li>Contaminant identification</li><li>At-line manufacturing support</li></ul><h4><strong>Polymer Analysis</strong></h4><ul><li>Polymer identification</li><li>Additive verification</li><li>Material degradation studies</li><li>Packaging material quality control</li><li>Composite material characterization</li></ul><h4><strong>Education and Academic Research</strong></h4><ul><li>FTIR teaching laboratories</li><li>Functional group identification</li><li>Student training and practical exercises</li><li>Research applications</li></ul><h4><strong>Battery Materials and Components</strong></h4><ul><li>Electrolyte characterization</li><li>Material verification</li><li>Quality control of battery components</li><li>Monitoring material changes affecting battery performance and safety</li></ul><h4><strong>Gemology and Mineral Analysis</strong></h4><ul><li>Gemstone identification</li><li>Mineral composition analysis</li><li>Authentication of treated and untreated gemstones</li></ul><h4><strong>Automotive Materials</strong></h4><ul><li>Polymer and composite characterization</li><li>Interior material verification</li><li>Fuel additive analysis</li><li>Material development and failure investigations</li></ul><h4><strong>Lubricants and Oils</strong></h4><ul><li>Lubricant condition monitoring</li><li>Formulation verification</li><li>Contamination detection</li><li>Predictive maintenance programs</li></ul><h3><strong>Benefits</strong></h3><ul><li>Highest-performance model in the Nicolet Summit product family</li><li>Superior spectral resolution for advanced analytical applications</li><li>Integrated touchscreen interface for streamlined operation</li><li>Long-term reliability backed by a 10-year optical system warranty</li><li>Advanced compliance and data integrity capabilities</li><li>Flexible platform for QA/QC, regulated laboratories, and research</li><li>Cloud-enabled collaboration and remote data access</li><li>Compact design with a small laboratory footprint</li></ul><p>The <strong>Thermo Scientific™ Nicolet™ Summit™ PRO FTIR Spectrometer </strong>combines high-resolution optics, advanced software, touchscreen operation, and regulatory-ready workflows in a powerful platform designed for modern analytical laboratories. Whether used for quality control, materials characterization, compliance testing, or research, the Summit PRO delivers the highest level of performance available within the Nicolet Summit FTIR family.</p>

Thermo Scientific Nicolet Summit OA FTIR Spectrometer

Dedicated FTIR analyzer for oils, liquids, syrups, and pastes. Features an integrated ZnSe HATR accessory, OMNIC Paradigm software, and rapid qualitative and quantitative analysis.

<p><strong>The Thermo Scientific™ Nicolet™ Summit™ OA FTIR Spectrometer is a dedicated analyzer designed for rapid characterization of oils, liquids, syrups, and viscous samples. Featuring an integrated zinc selenide (ZnSe) horizontal attenuated total reflectance (HATR) accessory, the system provides a constant and reproducible pathlength, making it ideal for both qualitative and quantitative analysis. Its rugged, spill-resistant design and compact footprint make it particularly well suited for QA/QC laboratories and routine industrial testing.</strong></p><p>Powered by the proven LightDrive™ Optical Engine and intuitive OMNIC™ Paradigm Software, the Summit OA delivers reliable performance, simplified workflows, and rapid results. Built-in workflow automation, multivariate analysis capabilities, and seamless cloud connectivity help laboratories improve efficiency while maintaining confidence in analytical data.</p><h3><strong>Key Features</strong></h3><ul><li>Dedicated FTIR analyzer for oils, liquids, syrups, and pastes</li><li>Integrated 40° ZnSe HATR accessory for rapid qualitative and quantitative analysis</li><li>Enhanced sensitivity through multi-reflection HATR technology</li><li>Up to 8× higher absorbance than conventional single-bounce ATR accessories</li><li>LightDrive™ Optical Engine for reliable long-term performance</li><li>10-year warranty on the interferometer, laser, and infrared source</li><li>OMNIC™ Paradigm Software with customizable workflows</li><li>Built-in Windows® 10 computer</li><li>LightBar LED status indicator</li><li>Integration with Thermo Scientific™ TQ Analyst™ software</li><li>User-replaceable ZnSe HATR crystal plate</li><li>Compact, rugged, and spill-resistant design</li></ul><h3><strong>Software Features</strong></h3><p><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2456"><strong>OMNIC™ Paradigm Software </strong></a>provides a flexible and intuitive environment for routine testing, material identification, and quantitative analysis.</p><h4><strong>Key software capabilities include:</strong></h4><ul><li>Spectral acquisition and processing</li><li>Workflow creation and automation</li><li>Visual workflow builder with drag-and-drop functionality</li><li>Spectral comparison and optimization tools</li><li>Multi-component searching</li><li>Cloud-based data access and collaboration</li><li>Integration with Thermo Fisher Connect</li><li>Support for qualitative and quantitative workflows</li><li>Integration with TQ Analyst™ for multivariate analysis</li><li>Packaged workflows for routine operator use</li></ul><h3><strong>Multiple Operating Modes</strong></h3><p><strong>Touchscreen Mode</strong></p><ul><li>Simple click-and-go operation</li><li>Apply → Measure → Clean workflow</li></ul><p><strong>Desktop Mode</strong></p><ul><li>Workflow creation</li><li>Spectral processing and comparison</li><li>Instrument optimization and method development</li></ul><p><strong>Operator Mode</strong></p><ul><li>Password-protected application packages</li><li>Controlled access to predefined workflows, calibrations, and diagnostics</li></ul><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Beam Splitter:</strong> KBr/Ge mid-infrared optimized</li><li><strong>Optical Components:</strong> LightDrive™ Optical Engine including source, laser, interferometer, and detector</li><li><strong>Detector Type:</strong> Fast-recovery deuterated triglycine sulfate (DTGS) detector</li><li><strong>Sampling Accessory:</strong> Integrated zinc selenide (ZnSe) Horizontal ATR (HATR)</li><li><strong>Dimensions (D × W × H):</strong> 32 × 34 × 24 cm (12.7 × 13.3 × 9.6 in.)</li><li><strong>Applications:</strong> Oils, Liquids, Syrups and Pastes, QA/QC, Food &amp; Beverage, Automotive</li><li><strong>Source Type:</strong> Single-point IR source with non-migrating hotspot for unmatched data reproducibility</li><li><strong>Spectral Range:</strong> 6000–650 cm⁻¹</li><li><strong>Electrical Requirements:</strong> 100/240 V, 47/63 Hz, 110 W</li><li><strong>Weight:</strong> 12.6 kg (27.8 lb)</li><li><strong>Warranty:</strong> 10 years on the interferometer, laser, and infrared source</li></ul><h3><strong>Typical Applications</strong></h3><h4><strong>Lubricants and Oils</strong></h4><ul><li>In-service lubricant analysis</li><li>Oil condition monitoring</li><li>Compliance with ASTM D7418, ASTM E2412, and JOAP methods</li><li>Predictive maintenance programs</li></ul><h4><strong>Food and Beverage</strong></h4><ul><li>Edible oil quality control</li><li>Verification of frying oil condition</li><li>Consistency monitoring of food products</li><li>Syrup and beverage analysis</li></ul><h4><strong>Fuels and Biofuels</strong></h4><ul><li>Determination of FAME content in diesel fuel</li><li>Compliance with ASTM D7371</li><li>Biodiesel blend quality control</li></ul><h4><strong>Quality Control and Manufacturing</strong></h4><ul><li>Incoming goods inspection</li><li>Product verification</li><li>Batch-to-batch consistency monitoring</li><li>Routine QA/QC testing</li></ul><h4><strong>Customer-Specific Applications</strong></h4><ul><li>Qualitative material identification</li><li>Quantitative analysis</li><li>Process monitoring</li><li>Custom workflow development</li></ul><h3><strong>Benefits</strong></h3><ul><li>Optimized specifically for liquid and viscous samples</li><li>High sensitivity through integrated multi-reflection HATR technology</li><li>Reduced risk of sample spills damaging the instrument</li><li>Fast, reproducible measurements with minimal sample preparation</li><li>Simplified workflows for routine operators</li><li>Rugged design suitable for industrial environments</li><li>Seamless integration of qualitative and quantitative analysis</li><li>Long-term reliability backed by a 10-year optical system warranty</li></ul><p>The Thermo Scientific™ Nicolet™ Summit™ OA FTIR Spectrometer combines dedicated liquid-sample analysis, integrated HATR technology, intuitive software, and proven FTIR performance in a compact platform designed for routine quality control and industrial testing. Whether analyzing lubricants, edible oils, fuels, syrups, or other liquid products, the Summit OA delivers fast, reliable, and reproducible results.</p>

Thermo Scientific Nicolet Apex FTIR Spectrometer

High-performance FTIR spectrometer featuring the LightDrive™ Optical Engine, advanced automation, OMNIC™ Paradigm software, and extensive accessory compatibility for research, QA/QC, and regulated laboratories.

<h5><strong>Advanced FTIR Performance for Research and Routine Analysis</strong></h5><p><strong>The Thermo Scientific™ Nicolet™ Apex FTIR Spectrometer is a premium Fourier Transform Infrared (FTIR) spectrometer designed for laboratories that require exceptional analytical performance, operational flexibility, and regulatory compliance. Suitable for both routine quality control and advanced research applications, the Nicolet Apex combines cutting-edge optical technology, powerful automation, and intuitive software to deliver accurate and reliable results across a broad range of industries.</strong></p><p>At the heart of the system is the proprietary <strong>LightDrive™ Optical Engine</strong>, which provides outstanding spectral quality, excellent sensitivity, and long-term stability. Combined with the OMNIC™ Paradigm software platform and extensive accessory compatibility, the Nicolet Apex helps laboratories increase productivity, improve data quality, and streamline analytical workflows.</p><h3><strong>Key Features</strong></h3><ul><li>High signal-to-noise ratio for demanding analytical applications</li><li>Excellent spectral resolution for detailed molecular characterization</li><li>Patented Smart Background technology for faster measurements and increased throughput</li><li>Multi-sample compartment design for enhanced workflow efficiency</li><li>Multi-detector capability allowing rapid switching between analytical configurations</li><li>Compatible with hundreds of FTIR accessories and sampling techniques</li><li>Seamless integration with FTIR microscopes, TGA-IR systems, gas cells, and automation accessories</li><li>Support for high-throughput and unattended operation</li><li>Remote instrument health monitoring services</li><li>10-year warranty on the interferometer, laser, and infrared source</li></ul><h3><strong>LightDrive™ Optical Engine</strong></h3><p>The Nicolet Apex is built around Thermo Scientific’s advanced LightDrive™ Optical Engine, engineered to deliver exceptional analytical performance and long-term reliability.</p><h4><strong>Advanced Michelson Interferometer</strong></h4><ul><li>High-resolution optical design for superior spectral quality</li><li>Excellent wavelength precision and reproducibility</li><li>Enhanced performance for complex and challenging samples</li></ul><h4><strong>Fast-Recovery DLaTGS Detector</strong></h4><ul><li>Accurate identification and quantification of analytes</li><li>High sensitivity for routine and research applications</li><li>Stable long-term analytical performance</li></ul><h4><strong>High-Stability Infrared Source</strong></h4><ul><li>Consistent energy output for reliable spectral quality</li><li>Excellent peak shape and signal-to-noise performance</li><li>Improved measurement reproducibility</li></ul><h4><strong>Solid-State Diode Laser</strong></h4><ul><li>Temperature-stabilized design for maximum accuracy</li><li>Long operational lifetime</li><li>Reduced maintenance requirements</li></ul><h3><strong>Flexible Configuration and Automation</strong></h3><p>The Nicolet Apex platform can be configured to meet a wide variety of analytical requirements and laboratory environments.</p><ul><li>Available as Apex KBr, Apex XT-KBr, and Apex ZnSe configurations</li><li>Supports TE-MCT detectors for high-speed and high-sensitivity applications</li><li>Multi-sample compartment architecture allows multiple accessories to remain installed simultaneously</li><li>Compatible with automated samplers and high-throughput workflows</li><li>Easily integrated with FTIR microscopes for particle and failure analysis</li><li>Suitable for TGA-IR coupling and advanced gas analysis applications</li></ul><h3><strong>OMNIC™ Paradigm Software</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Nicolet_Apex_FTIR_Spectrometer_3_71addec4b8.jpg" alt="Thermo Scientific Nicolet Apex FTIR Spectrometer: Paradigm time series measurements for gas sample." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Nicolet_Apex_FTIR_Spectrometer_3_71addec4b8.jpg 160w," sizes="100vw" width="1007" height="979"></p><p>The Nicolet Apex is powered by <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2456"><strong>Thermo Scientific™ OMNIC™ Paradigm Software</strong></a>, providing an intuitive and powerful environment for data acquisition, processing, interpretation, and reporting.</p><h4><strong>Software Benefits</strong></h4><ul><li>User-friendly interface suitable for both beginners and experienced users</li><li>Customizable workflows and automation tools</li><li>Advanced spectral processing and interpretation capabilities</li><li>Integrated access to extensive FTIR spectral libraries</li><li>Efficient report generation and data management</li></ul><h4><strong>OMNIC™ Anywhere Cloud Connectivity</strong></h4><ul><li>Remote access to instrument data and functionality</li><li>Real-time collaboration from any location</li><li>Access from computers, tablets, and mobile devices</li><li>Ideal for collaborative and multi-site research environments</li></ul><h4><strong>Remote Instrument Health Monitoring</strong></h4><ul><li>Continuous monitoring of critical instrument components</li><li>Tracking of source, laser, and interferometer performance</li><li>Proactive support from Thermo Fisher Scientific specialists</li><li>Reduced downtime and improved instrument availability</li></ul><h3><strong>Regulatory Compliance</strong></h3><p>The Nicolet Apex FTIR Spectrometer is designed to support laboratories operating in highly regulated industries.</p><ul><li>Automated ASTM E1421 spectrometer performance testing</li><li>NIST-traceable validation standards</li><li>Support for ASTM, USP, Ph. Eur., JP, and CP requirements</li><li>Design Qualification (DQ), Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ) documentation</li><li>21 CFR Part 11 compliance support through OMNIC Paradigm Software</li><li>Electronic signatures, audit trails, and secure data management</li></ul><h3><strong>Applications</strong></h3><p>The versatility of the Nicolet Apex makes it suitable for a wide range of industries and research disciplines.</p><ul><li>Pharmaceutical analysis and quality control</li><li>Forensic investigations</li><li>Polymer and plastics characterization</li><li>Chemical and petrochemical analysis</li><li>Gas analysis</li><li>Materials science research</li><li>Semiconductor analysis</li><li>Microplastics identification</li><li>Environmental studies</li><li>Academic and teaching laboratories</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Nicolet_Apex_FTIR_Spectrometer_2_c7b1dc750e.jpg" alt="Thermo Scientific Nicolet Apex FTIR Spectrometer: Automated multi-region mapping analysis of microparticles collected from air on a gold coated slide." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Nicolet_Apex_FTIR_Spectrometer_2_c7b1dc750e.jpg 189w," sizes="100vw" width="951" height="786"></p><h3><strong>Benefits</strong></h3><ul><li>Exceptional spectral performance for both routine and advanced applications</li><li>Flexible platform with extensive accessory compatibility</li><li>Increased productivity through automation and intelligent workflow design</li><li>Comprehensive regulatory compliance support</li><li>Advanced cloud connectivity and remote monitoring capabilities</li><li>Long-term reliability backed by a 10-year optical component warranty</li><li>Suitable for QA/QC, R&amp;D, industrial, academic, and regulated laboratory environments</li></ul>

Thermo Scientific OMNIC Paradigm Software

Thermo Scientific OMNIC Paradigm Software streamlines FTIR data analysis with advanced spectral processing, automated workflows, secure data management, and an intuitive user interface.

<p><strong>Thermo Scientific™ OMNIC™ Paradigm Software is an intuitive FTIR data analysis solution that streamlines materials characterization and spectroscopy workflows. Featuring an updated user interface and dashboard, it provides easy navigation between instrument control, data management, and analytical workflows. Advanced spectral processing capabilities include Q-check, multi-component searching, and contamination analysis.</strong></p><h3><strong>OMNIC Paradigm Software benefits</strong></h3><ul><li>Modern Interface and navigation</li><li>Data security and retention</li><li>Agile management of large and complex data sets</li><li>Quick interpretation of challenging samples</li><li>Simple and rapid automated workflow development</li><li>Faster data collection</li><li>Partnership with Thermo Fisher Scientific experts</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_OMNIC_Paradigm_Software_2_a7d08a64a3.jpg" alt="Thermo Scientific OMNIC Paradigm Software" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_OMNIC_Paradigm_Software_2_a7d08a64a3.jpg 245w," sizes="100vw" width="650" height="339"></p><h3><strong>OMNIC Paradigm Software features</strong></h3><p><strong>Data sets</strong><br>Manage larger data sets, create multiple maps within a single session, generate trend charts from multiple spectra, and support multi-instrument data management.</p><p><strong>Interpret samples</strong><br>Analyze multiple spectral regions using multiple thresholds, perform multi-component analysis, and carry out post-analysis of time-series data within OMNIC Paradigm.</p><p><strong>Interface</strong><br>Modern tab-based interface with intuitive navigation, right-click annotation tools, and streamlined access to data and analysis functions.</p><p><strong>Workflows</strong><br>Create and automate workflows (macros) for routine analyses with easy-to-read, customizable sequences.</p><p><strong>Data collection</strong><br>Reduce data acquisition time by up to 50% using Smart Backgrounds and quickly create mosaic images.</p><p><strong>Data security</strong><br>Integrated cybersecurity features, audit trails, version and change history, with support for 21 CFR Part 11 and GMP/GLP compliance.</p><p><strong>Partnership</strong><br>Includes access to Thermo Scientific partnership resources, macro conversion tools, and a software development kit (SDK) for workflow customization.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_OMNIC_Paradigm_Software_3_5001306d0a.jpg" alt="Thermo Scientific OMNIC Paradigm Software" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_OMNIC_Paradigm_Software_3_5001306d0a.jpg 245w," sizes="100vw" width="650" height="338"></p><div><h3><strong>Instrument compatibility</strong></h3></div><div><div><div><div><ul><li>Nicolet RaptIR+ FTIR Microscope</li><li>Nicolet RaptIR FTIR Microscope</li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?category=218&amp;search=Summit"><strong>Nicolet Summit FTIR spectrometer family</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/2452"><strong>Nicolet Apex FTIR Spectrometer</strong></a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_OMNIC_Paradigm_Software_191a492c54.jpg" alt="Thermo Scientific OMNIC Paradigm Software" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_OMNIC_Paradigm_Software_191a492c54.jpg 245w," sizes="100vw" width="650" height="338"></p></div></div></div></div>

Thermo Scientific Nicolet iS50R Research FTIR Spectrometer

Modular research FTIR spectrometer featuring 0.09 cm⁻¹ resolution, a patented Vectra-Piezo interferometer, and advanced capabilities including step-scan and time-resolved spectroscopy.

<p><strong>The Thermo Scientific™ Nicolet™ iS50R Research FTIR Spectrometer is a modular research-grade FTIR platform designed for advanced molecular spectroscopy. Featuring the patented Vectra-Piezo interferometer, step-scan capabilities, and flexible optical configurations, it delivers exceptional performance for demanding research applications in materials science, chemistry, pharmaceuticals, and academia.</strong></p><h3><strong>Key Features</strong></h3><ul><li>Research-grade FTIR spectrometer</li><li>Patented Vectra-Piezo interferometer</li><li>Continuous scan, rapid scan, and step-scan operation</li><li>Time-resolved and dual-channel spectroscopy</li><li>Spectral resolution up to <strong>0.09 cm⁻¹</strong></li><li>QuadraFlex™ four-position source mirror</li><li>Triple detector optics</li><li>Standard dual-channel digitizers</li><li>Auto-Tune functionality</li><li>Long-life Polaris™ infrared source</li><li>Touch Point™ one-touch sampling</li><li>High-speed USB 2.0 interface</li><li>Compatible with Smart Accessories</li><li>Expandable with ATR, Raman, NIR, GC-IR, microscope, and TGA modules</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Nicolet_i_S50_R_Research_FTIR_Spectrometr_e4146492f6.jpg" alt="Thermo Scientific Nicolet iS50R Research FTIR Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Nicolet_i_S50_R_Research_FTIR_Spectrometr_e4146492f6.jpg 210w," sizes="100vw" width="650" height="484"></p><h3><strong>OMNIC™ Research Software</strong></h3><p>The Nicolet iS50R is operated using <strong>Thermo Scientific OMNIC™ Research Software</strong>, providing comprehensive tools for advanced FTIR data acquisition and analysis.</p><h4><strong>Software capabilities include:</strong></h4><ul><li>Step-scan and time-resolved spectroscopy</li><li>FTIR amplitude, phase, and polarization modulation</li><li>Phase array processing</li><li>SpectraCorr™ 2D correlation spectroscopy</li><li>MacrosPro workflow automation</li><li>VCD intensity calibration</li><li>Advanced SST research tools</li></ul><h3><strong>Cloud Connectivity</strong></h3><p>The system supports <strong>OMNIC Anywhere</strong> and Thermo Fisher Cloud services, allowing users to securely store, access, share, and interpret spectral data from virtually any location.</p><h3><strong>Applications</strong></h3><ul><li>Advanced molecular spectroscopy</li><li>Materials science</li><li>Polymer research</li><li>Pharmaceutical research</li><li>Chemical analysis</li><li>Academic research</li><li>Time-resolved spectroscopy</li><li>Method development</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Nicolet_i_S50_R_Research_FTIR_Spectrometr_2_82dbff9e4e.jpg" alt="Thermo Scientific Nicolet iS50R Research FTIR Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Nicolet_i_S50_R_Research_FTIR_Spectrometr_2_82dbff9e4e.jpg 245w," sizes="100vw" width="650" height="335"></p><h3><strong>Technical Specifications</strong></h3><ul><li><strong>Beam Splitter:</strong> Far-IR, Mid-IR and Near-IR (gold) plus visible range (aluminum)</li><li><strong>Components:</strong> Sources, detectors and beamsplitters</li><li><strong>Detector Type:</strong> Three-position Paraflect detector mirror; Top-mounted DLaTGS Detector with KBr window</li><li><strong>Dimensions (L x W x H):</strong> 27 × 25 × 11 in. (69.8 × 62.6 × 27.6 cm)</li><li><strong>Electrical Requirements:</strong> 100/240 V, 50/60 Hz</li><li><strong>For Use With (Application):</strong> Materials science, photochemistry and optical research</li><li><strong>For Use With (Equipment):</strong> Smart Accessories; Nicolet iS50 modules; Nicolet Continuum Microscope</li><li><strong>Includes:</strong> with Aluminum Interferometer/Gold Interferometer</li><li><strong>Interface:</strong> USB 2.0</li><li><strong>Product Type:</strong> FTIR Spectrometer</li><li><strong>Source Type:</strong> Dual sources standard: Polaris™ long-life IR and visible/NIR Tungsten-Halogen</li><li><strong>Spectral Range:</strong> 10 to 27,000 cm⁻¹ depending upon configuration</li><li><strong>Spectral Resolution:</strong> 0.09 cm⁻¹</li><li><strong>Weight (English):</strong> 132 lb.</li><li><strong>Weight (Metric):</strong> 60 kg</li><li><strong>Width (English):</strong> 25 in.</li><li><strong>Width (Metric):</strong> 62.6 cm</li><li><strong>Performance Verification:</strong> ValPro and SPV</li><li><strong>Voltage:</strong> 100/240 V</li></ul>

Thermo Scientific OMNIC Series Software

Thermo Scientific™ OMNIC™ Series Software extends the OMNIC™ Software Suite with advanced tools for acquiring, visualizing, processing, and analyzing data from time-based spectroscopy experiments.

<p><strong>Thermo Scientific™ OMNIC™ Series Software is part of the Thermo Scientific™ OMNIC™ Software Suite and provides advanced tools for time-based spectroscopy experiments, including data acquisition, visualization, processing, and analysis. It enables researchers to efficiently move from data collection to meaningful analytical results.</strong></p><p>The software supports a wide range of time-based spectroscopy applications, including <strong>TGA-IR, GC-IR, FT-IR, Surface Plasmon Resonance (SPR), and Raman kinetics studies</strong>. When used together with <strong>Thermo Scientific™ OMNIC™ Professional Software</strong>, it further extends data acquisition, processing, and analytical capabilities for demanding research applications.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_OMNIC_Series_Software_2_cf423eec55.jpg" alt="Thermo Scientific OMNIC Series Software" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_OMNIC_Series_Software_2_cf423eec55.jpg 173w," sizes="100vw" width="650" height="587"></p><h4><strong>Flexible Experiment Setup</strong></h4><ul><li>Configure standard time-based experiments, including GC-IR, TGA-IR, and kinetics measurements</li><li>Support for timed and event-triggered data acquisition</li><li>Flexible experiment configuration for complex analytical workflows</li></ul><h4><strong>Advanced Data Extraction</strong></h4><ul><li>Create multiple user-defined time profiles during acquisition or post-processing</li><li>Analyze data using Gram-Schmidt Reconstruction (GSR), chemigrams, peak area and peak height calculations</li><li>Compatible with <strong>Thermo Scientific™ TQ Analyst™ Software</strong> quantitation methods</li><li>Reveal hidden chemical information through configurable time profiles</li></ul><h4><strong>Powerful Data Visualization</strong></h4><ul><li>Specialized 2D and 3D visualization tools</li><li>Interactive data exploration for large time-series datasets</li><li>Detailed visualization of subtle molecular changes</li><li>Fully configurable display and analysis environment</li></ul><h4><strong>Comprehensive Data Analysis</strong></h4><ul><li>Integrated access to OMNIC™ Professional Software processing and analysis tools</li><li>Analyze complete time-series datasets or individual spectra</li><li>One-click spectral library searching for rapid material identification</li><li>Compatible with Thermo Scientific™ spectral library collections</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_OMNIC_Series_Software_3_78d4c3bf1c.jpg" alt="Thermo Scientific OMNIC Series Software " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_OMNIC_Series_Software_3_78d4c3bf1c.jpg 245w," sizes="100vw" width="650" height="412"></p><h4><span><strong>Supported Techniques</strong></span></h4><ul><li>TGA-IR</li><li>GC-IR</li><li>Time-resolved FT-IR spectroscopy</li><li>Raman kinetics</li><li>Surface Plasmon Resonance (SPR)</li><li>Time-series spectroscopy</li></ul>

Wiley NIST/EPA/NIH EI Mass Spectral Library 2026

The NIST / EPA / NIH EI Mass Spectral Library 2026 from Wiley provides over 431,000 EI spectra, an expanded GC Retention Index Library, and updated NIST MS Search software with integrated chromatogram analysis for confident GC-MS compound identification.

<p><strong>The NIST / EPA / NIH EI Mass Spectral Library 2026, developed by the National Institute of Standards and Technology (NIST), is one of the world's most trusted mass spectral libraries for GC-MS compound identification. Built on more than four decades of development, the 2026 release contains over 431,000 critically evaluated EI spectra representing more than 376,000 unique compounds, supporting reliable identification across environmental, forensic, pharmaceutical, food, and industrial applications.</strong></p><p>The library includes the <strong>Electron Ionization (EI) Mass Spectral Library</strong>, <strong>GC Retention Index (RI) Library</strong>, and the <strong>NIST 2026 software suite</strong> featuring <strong>MS Search, AMDIS, and MS Interpreter</strong>. New in this release is integrated <strong>GC-MS chromatogram analysis</strong>, streamlining data processing and library searching within a single workflow.</p><p>The updated <strong>GC Retention Index Library</strong> now contains <strong>more than 527,900 RI values</strong>, while the EI library has been expanded with <strong>over 35,000 new compounds</strong>, focusing on biologically, environmentally, and industrially relevant analytes.</p><p>Available from Wiley in <strong>native formats for most major GC-MS instrument vendors</strong>, NIST 2026 is compatible with current and legacy mass spectrometry data systems and can also be supplied in bundles with <strong>KnowItAll</strong> software.</p>

GCMS/LCMS screening for contamination

GCMS/LCMS screening for identification of contaminants in samples, with the analytical method selected according to sample type.

<p><strong>The GCMS/LCMS Screening for Contamination is a standalone laboratory service designed to identify potential contaminants in a sample using either gas chromatography–mass spectrometry (GCMS) or liquid chromatography–mass spectrometry (LCMS).</strong></p><p>The appropriate analytical method depends on the sample type. GCMS is used primarily for volatile and semi-volatile compounds, while LCMS is suitable for peptide-related contamination.</p><h4><strong>About the Screening</strong></h4><ul><li><strong>GCMS screening</strong> uses the <strong>NIST 2014 </strong>mass spectral library to identify a broad range of potentially <span style="font-weight:400;">harmful substances in the product</span>. Detection is limited to volatile and semi-volatile compounds and this method is not suitable for peptide samples.<br>&nbsp;</li><li><strong>LCMS screening</strong> is intended for peptide products and can detect contamination with other peptides or degraded peptide. Detection is limited to peptides included in the laboratory’s available reference list.</li></ul><p>Both methods provide identification of detected contaminants only. Quantitative determination of a detected substance can be offered separately.</p><h4><strong>Key Features</strong></h4><ul><li>Standalone contamination screening by GCMS or LCMS</li><li>Analytical method selected according to sample type</li><li>GCMS screening for volatile and semi-volatile contaminants</li><li>GCMS identification using the NIST 2014 mass spectral library</li><li>LCMS screening for peptide contamination and degraded peptide</li><li>Identification of detected contaminants</li><li>Quantitative determination available separately after identification</li><li>Suitable for tablets, capsules, liquid solutions, raw materials, and vials depending on the selected method</li><li>Average turnaround time of 7 business days</li></ul><h4><strong>Analysis Parameters</strong></h4><ul><li><strong>Testing method: </strong>GCMS or LCMS</li><li><strong>Amount of sample required: </strong>1 tablet/capsule, 1 ml solution, 200 mg raw material, or 1 vial</li><li><strong>Average turnaround time: </strong>7 business days</li></ul><blockquote><p><strong>Important Notice</strong></p><ul><li>The analytical method is selected according to the type of sample and the expected contaminants.</li><li>GCMS detection is limited to volatile and semi-volatile compounds and cannot be used for peptide samples.</li><li>LCMS detection is limited to peptides included in the laboratory’s available reference list.</li><li>Both GCMS and LCMS screening provide identification only. Quantitative determination of a detected contaminant is not included in the standard analysis and can be offered separately.</li></ul></blockquote><h4><strong>Optional Additional Analyses</strong></h4><p>The following optional laboratory services are available:</p><ul><li>Additional Laboratory Report</li></ul>

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