Normal Phase Solid Phase Extraction (SPE)
A polar phase with slight hydrophobic selectivity in reversed phase mode and moderate polar selectivity in normal phase mode.
Phenomenex: Strata-CN- Surface Area (m²/g): -
- Separation Mode: Normal Phase
- Particle Size: 55
- Recommended Use: Extraction of polar compounds such as those that contain hydroxyl groups.
Starting Method
- Condition: IPA/DCM
- Equilibrate: Hexane
- Load: Pretreated sample
- Wash: 5 % DCM in Hexane
- Elute: 1:1 Hexane / DCM or 1:1 Hexane / IPA
Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.
