Ion-Exchange Solid Phase Extraction (SPE) Sorbent
A benzene sulfonic acid group is bonded to the surface of the silica particle, giving strong cation-exchange selectivity.
- Extraction of 1 °, 2 °, and 3 amines
Phenomenex: Strata SCX- Surface Area (m²/g): -
- Separation Mode: Ion Exchange
- Particle Size: 55
- Recommended Use: Extraction of weakly basic compounds
Starting Method
Strata SCX – Strong Cation-Exchange
- Condition: 1 mL Methanol
- Equilibrate: 1 mL Acidified Water
- Load: Pretreated sample (acidified)
- Wash 1: 1 mL 0.1N HCl in Water
- Wash 2: 1 mL 0.1N HCl in Methanol, dry under vacuum for 2-5 min
- Elute: 1 mL 5 % NH4OH in Methanol
Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.


