<p><strong>Taťána Gazárková is currently a&nbsp;postdoctoral fellow in the Laboratory of Antibiotic Resistance and Microbial Metabolomics. During her doctoral studies, she focused on chromatography and mass spectrometry. Recently, she was awarded second place in the “Sanofi Prize for Pharmacy 2026” competition.</strong></p><p><strong>Taťána Gazárková </strong>is currently a&nbsp;postdoctoral fellow in the <strong>Laboratory of Antibiotic Resistance and Microbial Metabolomics</strong>. During her doctoral studies, she focused on chromatography and mass spectrometry. Recently, she was awarded second place in the <strong>“Sanofi Prize for Pharmacy 2026” </strong>competition, which is awarded by the<strong> French Embassy in the Czech Republic</strong> for her dissertation – Steroid Analysis Using Modern Chromatographic and Mass Spectrometry Techniques: From Fundamental Studies to Targeted Bioanalytical Applications (supervisor: <strong>Lucie Nováková, Charles University</strong>).&nbsp;</p><h5><strong>What makes this field particularly exciting or unique in your view?</strong></h5><p>What I&nbsp;enjoy about analytical chemistry is that, to a&nbsp;certain extent, it is a&nbsp;kind of detective work. You are often looking for ways to “make the invisible visible”. In other words, extract the information you are interested in from a&nbsp;complex sample and then interpret it correctly. What also appeals to me about bioanalytical chemistry is its interdisciplinary nature. It brings together analytical chemistry, biochemistry, biology and medicine, which means that you need to be able not only to translate a&nbsp;biological or clinical question into a&nbsp;measurable analytical experiment, but also to place the resulting data back into a&nbsp;broader biological context. This combination of different perspectives is probably what I&nbsp;enjoy most about the field. At the same time, there is still plenty of room for fundamental research, ranging from studying analytical techniques themselves and improving them to developing new methodological approaches.</p><h5><strong>How did you end up at the </strong><a target="_blank" rel="noopener noreferrer" href="https://mbu.cas.cz/en/research/laboratory-of-antibiotic-resistance-and-microbial-metabolomics"><strong>Laboratory of Antibiotic Resistance and Microbial Metabolomics</strong></a><strong>, and what project are you currently working on?</strong></h5><p>I came to the Institute of Microbiology through a&nbsp;joint project between<strong> Dr Zdeněk Kameník and Assoc. Prof. Jan Bobek from the First Faculty of Medicine, Charles University</strong>. For me, it was also an opportunity to move from targeted analysis and the study of chromatographic techniques towards untargeted metabolomics and new biological questions.</p><p>In the project, we are trying to identify new biologically active compounds that would be effective, particularly against pathogenic fungi. As a&nbsp;potential source of such compounds, we study streptomycetes, bacteria known for their ability to produce a&nbsp;wide range of biologically active compounds, including many antibiotics that are currently in clinical use. We focus on less-explored host-associated streptomycetes, in which we had already observed antifungal activity in previous experiments. We are especially interested in strains active against Candida albicans whose activity cannot be explained by the presence of a&nbsp;known bioactive compound. These strains may represent an interesting source of novel compounds. We then integrate the results of untargeted metabolomic analyses with genomic analyses, which allows us to obtain a&nbsp;more comprehensive view of the biosynthetic potential of selected strains.</p><h5><strong>You also took part in this year’s Vědafest, a&nbsp;science outreach event for the public. What was it like?</strong></h5><p>I already had some experience with science outreach through events such as Researchers’ Night and the Science Fair at my previous institution, but this year’s Vědafest was still new to me in some ways. This time, I&nbsp;was presenting a&nbsp;field that I&nbsp;myself had entered only relatively recently. It was therefore more challenging to find the right analogies and explain the essence of the topic in a&nbsp;way that was simple, yet precise and scientifically accurate. At the same time, that was exactly what made it inspiring. It forces you to look at your own work from a&nbsp;different perspective. What I&nbsp;enjoyed most was the spontaneity and curiosity of the children, who often came up with questions that would never even occur to an adult.</p><h5><strong>What are the biggest challenges you face on your scientific journey, and what helps you overcome them?</strong></h5><p>One of the greatest, but at the same time most interesting, challenges is, in my view, the uncertainty that is inseparably linked to research. For a&nbsp;long time, you often do not know whether you have taken the right direction in addressing a&nbsp;particular question or whether you will ultimately manage to find that figurative final piece of the puzzle. At the same time, this uncertainty is precisely what makes science exciting for me.</p><p>Another major challenge, particularly in interdisciplinary projects, is communication. It is important from the very formulation of a&nbsp;hypothesis and the planning of experiments through to the interpretation of results, including negative ones, and placing them in a&nbsp;broader context. To some extent, every field has its own language, and finding a&nbsp;common understanding is not always straightforward. Personally, I&nbsp;find it very helpful to be able to discuss problems with colleagues on an ongoing basis, whether individually or during regular laboratory seminars. One of the major strengths of our current group is its interdisciplinary nature, which allows me to look at the same problem from several different perspectives. It is also important for me not to lose my curiosity, because that is ultimately what leads us to ask further questions.</p><h5><strong>What are your plans after completing your PhD?</strong></h5><p>After finishing my PhD, I&nbsp;decided that I&nbsp;do not need to have everything that comes next precisely mapped out straight away. I&nbsp;would like to keep different options open for a&nbsp;while and continue building on my experience in analytical chemistry, while at the same time connecting it with other areas that have a&nbsp;biological or medical relevance. I&nbsp;believe that we can keep learning throughout our lives, so I&nbsp;am quite curious to see where the next stage of my journey will take me.</p><p><i>Thank you for the interview!</i></p>

Interview: What Drew Postdoc Taťána Gazárková to Analytical Chemistry

<p><strong>Per- and polyfluoroalkyl substances (PFAS) have earned the moniker "forever chemicals" due to their extreme persistence in the environment. Their detection is crucial for protecting public health and the environment as these synthetic compounds continue to pose significant challenges worldwide. This comprehensive exploration examines why PFAS detection matters, current detection methods, and future directions in addressing PFAS contamination.</strong></p><h3><strong>Understanding PFAS and Their Health Impacts</strong></h3><p>PFAS are a class of synthetic organic compounds with diverse structures, properties, and uses. Despite their diversity, all PFAS contain perfluoroalkyl moieties that are extremely resistant to environmental and metabolic degradation [1]. This high persistence is a defining characteristic that makes PFAS management particularly challenging.</p><h3><strong>Documented Health Effects</strong></h3><p>Current scientific research has linked PFAS exposure to numerous adverse health outcomes:</p><ul><li>Reproductive effects including decreased fertility and increased high blood pressure in pregnant women [8]</li><li>Developmental effects in children such as low birth weight, accelerated puberty, and behavioral changes [8]</li><li>Reduced immune system function, including decreased vaccine response</li><li>Interference with natural hormones and endocrine disruption</li><li>Increased cholesterol levels and obesity risk</li><li>Increased risk of several cancers, including prostate, kidney, testicular, oral cavity/pharynx, brain, and endocrine cancers [3]</li></ul><p>A 2023 study linked PFAS-contaminated water with up to a <strong>33% increase in cancer incidence</strong> in affected areas [3]. The study compared regions with elevated PFAS levels to cancer data from the National Cancer Institute, finding higher incidences of various cancers after controlling for factors like smoking and obesity.</p><h3><strong>Environmental Persistence and Contamination</strong></h3><p>The extreme persistence of PFAS represents a fundamental concern for environmental management. PFAS are considered the most environmentally persistent substances among organic chemicals [7]. This persistence means that even if all PFAS uses were immediately phased out, existing contamination would continue to affect ecosystems and water supplies for generations.</p><p>A 2023 study at a military fire training site estimated that PFAS contamination will persist for centuries without remediation [7]. The research found that terminal PFAS still exceed regulatory limits by 2000-fold decades after aqueous film-forming foam (AFFF) use ceased, with precursors accounting for around half of the extractable organofluorine across years.</p><h3><strong>Current Detection Methods</strong></h3><h4><strong>EPA Standardized Methods</strong></h4><p>The<strong> Environmental Protection Agency (EPA</strong>) has developed several standardized methods for PFAS detection, each with specific applications and capabilities:</p><h5><strong>EPA Method 533</strong></h5><p><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/epa-533-drying-down-pfas-samples-after-spe"><strong>EPA Method 533</strong></a> focuses on "short chain" PFAS with carbon chain lengths of<strong> C4 to C12</strong>. Released in December 2019, this method complements Method 537.1 and includes several key features:</p><ul><li>Uses isotope dilution quantification approach with extracted internal standards, which reduces overall analytical uncertainty</li><li>Employs weak anion exchange solid phase extraction cartridges as opposed to polystyrene divinylbenzene used in 537.1</li><li>Can analyze 25 PFAS compounds, including additional short-chain PFAS that were not apart of Method 537.1</li><li>Allows for longer holding times: 28 days to extraction and 28 days to analyze (compared to 14 days to extraction in Method 537.1)</li><li>Uses ammonium acetate as a preservative (versus Trisma in Method 537.1) [1]</li></ul><h5><strong>EPA Method 537/537.1</strong></h5><p><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/sample-concentration-epa-method-537-pfas-determination"><strong>EPA Method 537 </strong></a>was first published in 2009 for the determination of 14 PFAS in drinking water [6]. It was later updated to Method 537.1 in 2018 (with editorial updates in 2020) to expand its capabilities:</p><ul><li>Uses<a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/what-is-solid-phase-extraction-spe"><strong> solid phase extraction (SPE) </strong></a>and<a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/preparing-samples-for-lc-ms/ms-analysis"><strong> liquid chromatography/tandem mass spectrometry (LC-MS/MS)</strong></a></li><li>Method 537.1 expanded detection to 18 PFAS compounds, including HFPO-DA (one component of GenX technology)</li><li>Utilizes styrene-divinylbenzene (SDVB) media for extraction</li><li>Requires samples to be extracted within 14 days and analyzed within 28 days</li><li>Methanol is used to elute the extracts. This should then be reconstituted with a 96:4 methanol:water mixture [1]</li></ul><p>Together, Methods 533 and 537.1 can detect a total of <strong>29 unique PFAS compounds in drinking water </strong>and are approved for monitoring under the fifth Unregulated Contaminant Monitoring Rule (UCMR 5) and the PFAS National Primary Drinking Water Regulation [1] [3].</p><h5><strong>EPA Method 1633</strong></h5><p><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/preparing-diverse-sample-matrices-for-epa-method-1633"><strong>EPA Method 1633</strong></a>, released in 2024, represents a significant advancement in PFAS analysis:</p><ul><li>Developed for the analysis of <strong>40 PFAS compounds </strong>in various matrices, including surface water, groundwater, wastewater, soil, biosolids, sediment, landfill leachate, and fish tissue</li><li>Expands beyond the drinking water focus of Methods 533 and 537.1</li><li>Provides a standardized approach that may replace modified drinking water methods (i.e., modified EPA 537) that were previously used for non-drinking water matrices [1]</li></ul><h4><strong>Conventional Analytical Techniques</strong></h4><p>The gold standard for PFAS analysis involves chromatographic techniques coupled with mass spectrometry:</p><ul><li>Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) is the most widely used method for PFAS analysis, offering high sensitivity and specificity [1]</li><li>High-Resolution Mass Spectrometry (HRMS) allows for rapid detection and identification of PFAS species at very low concentrations [5]</li></ul><p>These techniques can detect PFAS at parts per trillion (ppt) levels, which is essential given the low concentrations at which PFAS can cause health effects [1]. However, these methods require sophisticated equipment, specialized training, and significant financial resources, making them inaccessible in many regions, particularly in developing countries.</p><h4><strong>Emerging Detection Technologies</strong></h4><p>Several innovative approaches are being developed to address the limitations of conventional methods:</p><ul><li>Electrochemical biosensors using modified electrodes have shown promise for selective PFAS detection with low detection limits [2]</li><li>Surface-Enhanced Raman Spectroscopy (SERS) uses metallic nanoparticles and can be made into a portable method for on-site testing [1]</li><li>Molecular imprinted polymers (MIPs) offer thermal and physical stability, reusability, and low-cost synthesis for PFAS detection [6]</li></ul><p>These emerging technologies aim to provide more accessible, field-deployable, and cost-effective alternatives to traditional laboratory-based methods.</p><h3><strong>Challenges in PFAS Detection</strong></h3><h4><strong>Analytical Challenges</strong></h4><p>Detecting PFAS presents several technical challenges:</p><ul><li>The ubiquity of PFAS in laboratory equipment and accessories can lead to background contamination when measuring at parts-per-trillion levels [1]</li><li>Many components in liquid chromatographs, mass spectrometers, and solid-phase extraction systems contain materials that can leach PFAS compounds [9]</li><li>The vast number of PFAS (thousands of compounds) makes comprehensive detection difficult, as analytical standards are only available for a small subset [1]</li><li>Complex matrices like food and environmental samples require sophisticated sample preparation techniques</li></ul><h4><strong>Global Disparities in Detection Capabilities</strong></h4><p>Access to PFAS detection technology varies significantly worldwide:</p><ul><li>Many developing regions, particularly in Africa, lack adequately equipped laboratories with the necessary instrumentation to detect and measure PFAS</li><li>There is often a scarcity of qualified professionals with experience in PFAS analysis in these regions</li><li>The high cost of acquiring and maintaining sophisticated analytical instruments presents a substantial obstacle to conducting extensive PFAS investigations in resource-limited settings [1]</li><li>Competing priorities such as infectious diseases, poverty, and food security often divert attention and resources from environmental pollutants like PFAS</li></ul><h4><strong>Regulatory Landscape and Compliance</strong></h4><p>The regulatory framework for PFAS is evolving rapidly worldwide:</p><ul><li>The EPA finalized Section 8(a)(7) of the Toxic Substances Control Act in September 2024, requiring manufacturers and importers to report on their use of PFAS since 2011 [10]</li><li>Electronic reporting for PFAS will open on July 11, 2025, with final reporting deadlines in 2026</li><li>Companies must report detailed information including chemical identity, production volumes, industrial and consumer products, worker exposure, and disposal methods [10]</li></ul><p>These regulations are driving demand for more effective and accessible PFAS detection methods to ensure compliance and protect public health.</p><h3><strong>Future Directions in PFAS Detection</strong></h3><h4><strong>Technological Advancements</strong></h4><p>The future of PFAS detection lies in developing more accessible, sensitive, and comprehensive methods:</p><ul><li>Non-targeted screening methods that can identify unknown PFAS compounds without requiring analytical standards for each specific compound</li><li>Total fluorine analysis techniques like Adsorbable Organic Fluorine and Total Oxidizable Precursor Assay that can quantify the presence of fluorine atoms within a sample [1]</li><li>Portable sensors and field-deployable technologies that enable on-site monitoring and rapid response to contamination events</li><li>AI-driven solutions that can improve data analysis and interpretation for complex PFAS mixtures</li></ul><h4><strong>Collaborative Approaches</strong></h4><p>Addressing the global challenge of PFAS detection requires coordinated efforts:</p><ul><li>International partnerships between researchers in developed and developing regions to enhance expertise and capacity building</li><li>Standardization of analytical methods to ensure consistency and comparability of results across different laboratories and regions</li><li>Open data sharing and collaboration across countries to leverage collective knowledge and resources</li><li>Integration of PFAS monitoring into broader environmental and public health surveillance systems</li></ul><h3><strong>Conclusion</strong></h3><p>The detection of PFAS is not merely a technical challenge but a critical public health and environmental imperative [1]. As these "forever chemicals" continue to persist in our environment, developing effective, accessible, and comprehensive detection methods becomes increasingly important. By advancing detection technologies, strengthening regulatory frameworks, and fostering global collaboration, we can better understand, monitor, and ultimately mitigate the impacts of PFAS contamination.</p><p>The EPA's standardized methods (533, 537.1, and 1633) provide crucial tools for monitoring PFAS in various environmental matrices, but continued innovation is needed to address the full spectrum of PFAS compounds and to make detection more accessible globally [1] [6]. The path forward requires sustained investment in research and development, capacity building in resource-limited settings, and a commitment to environmental justice that ensures all communities have access to the tools and information needed to protect themselves from PFAS exposure. Only through such comprehensive approaches can we hope to address the complex challenges posed by these persistent pollutants.</p><p><span>Be sure to check out our other installments of our&nbsp;</span><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/introducing-our-environmental-contaminants-series-making-sense-of-the-alphabet-soup"><span>Environmental Contaminant Series</span></a><span>&nbsp;covering&nbsp;</span><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/the-importance-of-detecting-persistent-organic-pollutants-pops"><span>Persistent Organic Pollutants (POPs)</span></a><span>,&nbsp;</span><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/the-importance-of-detecting-polycyclic-aromatic-hydrocarbons-pahs"><span>Polycyclic Aromatic Hydrocarbons (PAHs)</span></a><span>,&nbsp;</span><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/the-importance-of-detecting-semi-volatile-organic-compounds-svocs"><span>Semi-Volatile Organic Compounds (SVOCs)</span></a><span>, and </span><a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/the-importance-of-detecting-polychlorinated-biphenyls-pcbs"><span>Polychlorinated Biphenyls (PCBs)</span></a><span>.</span></p>

The Importance of Detecting Per- and Polyfluoroalkyl Substances (PFAS)

News from LabRulezLCMS Library - Week 36, 2026

Article

Application

Scientists

Environment

Water

Interview

The Czech Academy of Sciences (CAS) was established by Act No. 283/1992 Coll. as the Czech successor of the former Czechoslovak Academy of Sciences. It is set up as a complex of 54 public research institutions.

Czech Academy of Sciences

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Agilent Technologies

US HUPO

Technology Networks

Phenomenex

Thermo Fisher Scientific

SCIEX

Waters Corporation

<p><strong>This webinar introduces the fundamentals of monoclonal antibody (mAb) Critical Quality Attributes (CQAs) and the LC workflows commonly used to assess them. We’ll begin with an overview of mAb heterogeneity and the major CQA categories, including size, charge, hydrophobic and structural variants, plus common post-translational modifications.</strong><br><br>The session will then connect these CQAs to the chromatographic techniques most commonly used for characterization, including size exclusion chromatography (SEC), ion exchange chromatography (IEX), and reversed-phase LC (RPLC). Attendees will gain a practical understanding of what each technique measures, how the methods complement one another, and why they are important in biopharmaceutical analysis.</p><h4><strong>Key Learning Points</strong></h4><ul><li>Describe monoclonal antibodies (mAbs), including their basic structure, production, and role as therapeutic medicines.</li><li>Define Critical Quality Attributes (CQAs) and their relationship to product quality, safety, and performance.</li><li>Introduce key LC techniques used in mAb characterization, including SEC, IEX, and RP-LC.</li><li>Explain what each technique measures, how they complement each other in mAb workflows, and how to select appropriate methods for different CQAs.</li></ul><h4><strong>Who Should Attend</strong></h4><ul><li>Any chromatography users working with or interested in monoclonal antibody (mAb) analysis and characterization by LC. &nbsp;</li></ul><h4><strong>Viewing Options</strong></h4><h5><strong>Session 1</strong></h5><p><strong>Tuesday, July 28, 2026</strong></p><ul><li>Los Angeles: 10:00 AM PT | New York: 1:00 PM EST</li><li>Mexico City: 12:00 PM CDT</li></ul><h5><strong>Session 2</strong></h5><p><strong>Wednesday, July 29, 2026</strong></p><ul><li>London: 9:00 AM BST | Berlin: 10:00 AM CEST&nbsp;</li><li>Mumbai: 1:30 PM IST</li></ul><blockquote><p><strong>Presenter: </strong>Lucia Geis Asteggiante (Senior Technical Specialist, Phenomenex)</p><p>Lucia is a Senior Technical Specialist that has recently joined Phenomenex’s Global Technical Team. She has a broad experience in the field of Analytical Chemistry with a particular focus on LC chromatography coupled with mass spectrometry. Lucia comes from a strong academic and regulatory background with experiences ranging from method development and analysis of small molecules to large protein complexes. She gained her Ph.D. at the University of Maryland - College Park, USA and did her post-doctoral work at the University of Oxford, UK. During her time as a researcher, she has authored/co-authored 23 scientific publications and 2 book chapters.&nbsp;</p></blockquote>

Phenomenex: Fundamentals First Bio Series - A Beginner’s Roadmap to mAb CQAs and LC Workflows

Fundamentals First Bio Series: A Beginner’s Roadmap to mAb CQAs and LC Workflows

Introduction to monoclonal antibody (mAb) CQAs. Explore how size exclusion, ion exchange, and reversed-phase LC workflows analyze bioheterogeneity.

Beginner’s Roadmap to mAb CQAs and LC Workflows

<h4><strong>Optimize Upstream Control with Data‑Driven Cell Media Analysis &amp; Titer Assessment</strong></h4><p><strong>This session explores how advanced analytics enable tighter control of upstream bioprocesses. We begin with a walkthrough of recent work in cell culture media analysis, highlighting vitamin profiling as a tool to better understand nutrient utilization and process performance.</strong></p><p>The story continues with focus on optimizing titer measurement using analytical Protein A, demonstrating benefits such as higher sensitivity for measurement earlier in cell cultures, faster results, improved data quality, and reduced workflow complexity to support more informed, timely upstream decision‑making.</p><h5><strong>Key takeaways:</strong></h5><ul><li>Understand how advanced cell media analysis, including vitamin profiling, enhances understanding of nutrient utilization and upstream process performance.</li><li>Evaluate how analytical Protein A titer measurements enable earlier, faster, and more sensitive assessment of product formation during cell culture.</li><li>Apply data‑driven analytical insights to improve upstream process control, data quality, and decision‑making efficiency.</li></ul><h5><strong>This Webinar is designed for:</strong></h5><ul><li><strong>Upstream Process Development &amp; Engineering Teams</strong> – Scientists and engineers focused on media optimization, nutrient utilization, and improved process control.</li><li><strong>MSAT &amp; Process Characterization Professionals </strong>– Teams seeking deeper process understanding and data‑driven decision making across development and manufacturing.</li><li><strong>Analytical Development Scientists</strong> – Experts responsible for cell media and titer analysis who want faster, more sensitive, and streamlined analytical workflows.</li></ul><blockquote><p><strong>Speaker:</strong> Mark Wrona (Consulting Scientist, Biologics Business Unit, Waters Corporation)</p><p>Mark Wrona manages specialized teams of scientists developing analytical applications to support drug development and PAT applications.</p><p>He specializes in biologics and life sciences applications.He has 15 years with Waters and prior experience as a research chemist at a large pharma.</p></blockquote><blockquote><p><strong>Speaker:</strong> Fang Lu (Senior Upstream Process Development Scientist, Waters Corporation)</p><p>Dr. Fang Lu is a Senior Upstream Process Development Scientist at Immerse Delaware, Waters Corporation.</p><p>She has expertise in viral vector upstream process development, gene therapy manufacturing, and monoclonal antibody upstream development, with a focus on applying analytical tools to enhance process understanding and optimization.</p><p>Prior to joining Waters, Fang spent four years in the cell and gene therapy CDMO industry supporting process development for complex biologics and advanced therapy applications.</p></blockquote>

Data‑Driven Upstream Control: Optimizing Cell Media Analysis and Titer Assessment

Enhance upstream control with data-driven analytics. Discover how vitamin profiling in media and high-sensitivity Protein A titer assays speed up PD.

Optimizing Cell Media Analysis and Titer Assessment

<h4><strong>What’s trending across Asia and what you should know next</strong></h4><p><strong>PFAS Asia Summit is back in 2026! Join us with leading experts across science and industry to explore the latest PFAS developments shaping Asia. From evolving regulatory frameworks to cutting-edge research and analytical innovation, this summit offers a focused platform to understand emerging risks, industry responses - helping you stay informed and prepared in a rapidly changing PFAS landscape.</strong></p><h4><strong>What you will learn:</strong></h4><ul><li>Latest PFAS regulatory updates across global and Asian markets</li><li>Emerging PFAS trends in key industries, including agriculture, electronics, and pharmaceuticals</li><li>Advances in sample preparation and integrated LC-MS/MS technologies for PFAS detection and analysis</li></ul><h4><strong>Agenda</strong></h4><h5><strong>09:00 - 09:05 a.m. Welcome &amp; Introduction</strong></h5><h5><strong>09:05 - 09:35 a.m. PFAS around the world - Regulatory and analytical trends</strong></h5><ul><li>Holly Lee (SCIEX)</li></ul><h5><strong>09:35 - 10:05 a.m. Utilizing LC-MS for proactive PFAS detection in Pharma</strong></h5><ul><li>Eshani Galermo (SCIEX)</li></ul><h5><strong>10:05 - 10:35 a.m. Advanced strategies in LC-MS/MS for clean-up and analysis of PFAS compounds in various sample matrices</strong></h5><ul><li>Namrata Saxena (Phenomenex)</li></ul><h5><strong>10:35 - 11:00 a.m. Behavior and metabolic effects of PFAS in wheat</strong></h5><ul><li>Yanwei Zhang (China)<ul><li><i>*Speaking language: Chinese</i></li></ul></li></ul><h5><strong>11:00 - 11:25 a.m. Standardization of IEC test methods for PFAS regulation compliance in the electrical, electronics, and automotive plastic industries</strong></h5><ul><li>Jaehak Jung (Korea)<ul><li><i>*Speaking language: Korean</i></li></ul></li></ul><h5><strong>11:25 - 11:55 a.m. Nontarget screening of PFAS transformation products during photoelectrochemical degradation of PFAS in water</strong></h5><ul><li>Jheng-Sian, Yang (Taiwan)<ul><li><i>*Speaking language: Chinese</i></li></ul></li></ul><h5><strong>11:55 a.m. - 12:10 p.m. Q&amp;A</strong></h5><p><i>*Sessions delivered in non-English languages will be supported with English subtitles.</i></p><blockquote><p><strong>Speaker: </strong>Yanwei Zhang, Ph.D. (Associate Researcher, Agro-Environmental Protection Institute, Ministry of Agriculture and Rural Affairs, China)</p><p><strong>Speaker:</strong>&nbsp;Jaehak Jung, Ph.D. (Chief Technology Officer (CTO), Korea Institute of Analytical Science and Technology (KAIST), Republic of Korea)</p><p><strong>Speaker:</strong> Jheng-Sian Yang, Ph.D. (Assistant Professor, Department of Safety, Health and Environmental Engineering, National United University, Taiwan)</p><p><strong>Speaker:</strong> Holly Lee (Staff Scientist, Global Technical Marketing, Food, SCIEX)</p><p><strong>Speaker:</strong> Eshani Galermo (Staff Scientist, Pharma/Biopharma Quant Lead, SCIEX)</p><p><strong>Speaker:</strong> Namrata Saxena (Technical Manager, Asia/Pacific, Phenomenex)</p><p><strong>Speaker:</strong> See Chung Yip (Field Application Manager, SCIEX)</p></blockquote>

PFAS Asia Summit 2026

Stay ahead of the changing PFAS landscape in Asia. Learn about evolving regulations, industry impacts, and cutting-edge LC-MS/MS analytical methods

PFAS Asia Summit 2026: Trends, Regulations & LC-MS/MS  

<p><strong>Discover how mass spectrometry imaging is expanding beyond molecular detection in this US HUPO webinar featuring experts discussing innovative imaging approaches and emerging biomedical applications.</strong></p><blockquote><p><strong>Presenter: </strong>Dr. Angela Kruse (Assistant Professor, The Ohio State University)</p><p><strong>Presenter: </strong>Dr. Yasmin Shanneik (Postdoctoral Associate Baylor College of Medicine)</p><p><strong>Moderator: </strong>Dr. Jessica Moore</p><p><strong>Moderator: </strong>Dr. Colleen Crouch</p></blockquote>

US HUPO: Spatial Imaging Series: More Than Mass Spec

Spatial Imaging Series: More Than Mass Spec

Join the US HUPO webinar to explore advances in mass spectrometry imaging and innovative approaches beyond conventional MS analysis.

<div><p><strong>As adeno-associated virus (AAV) therapies advance toward larger-scale manufacturing, achieving consistent full capsid enrichment remains a critical challenge. Variability between serotypes and purification conditions can affect product quality, recovery, and process scalability.</strong></p><p>In this webinar, Chiu Lau-Barre will share practical strategies for developing robust anion exchange (AEX) polishing workflows, drawing on real-world AAV2 and AAV9 examples.</p><p>Attendees will gain insight into approaches for improving purification performance, streamlining process development, and supporting efficient scale-up. The session will also highlight how modern screening tools can help accelerate decision-making and reduce development timelines.</p><h5><strong>Attend this webinar to:</strong></h5><ul><li>Understand key variables that influence AEX polishing performance of full/empty capsid separation for AAVs</li><li>Explore AAV2 and AAV9 case studies demonstrating how AEX polishing methods can be optimized across serotypes</li><li>Learn how high-throughput AEX screening can accelerate process development and support scalable workflow implementation</li><li>Identify process development strategies that can help reduce optimization timelines and support scale-up readiness</li></ul><blockquote><p><strong>Presenter:</strong> Chiu Lau-Barre (Staff Scientist, Field Applications at Thermo Fisher Scientific)</p><p>Chiu Lau-Barre is a staff scientist at Thermo Fisher Scientific, where she supports customers in purification process development and troubleshooting across a range of biomolecules, including antibodies and adeno-associated viral (AAV) vectors. With more than 15 years of biopharmaceutical industry experience, she has held scientific leadership roles at Pfizer and Eli Lilly, contributing to antibody and protein therapeutic development from early-stage screening through process development. Her expertise spans purification strategy, developability assessment and scalable bioprocess workflows. Chiu holds a bachelor's degree in Biochemistry from the University of California, Santa Barbara.</p></blockquote></div>

Technology Networks: Polishing Strategies for Full Adeno-Associated Capsid Enrichment

Polishing Strategies for Full Adeno-Associated Capsid Enrichment

In this webinar, strategies for developing robust anion exchange (AEX) polishing workflows, drawing on real-world AAV2 and AAV9 examples.

Strategies for Full Adeno-Associated Capsid Enrichment

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Today's analytical laboratories face increasing pressure to deliver faster turnaround times, higher sensitivity, and greater throughput while optimizing resources, controlling operating costs, and meeting sustainability objectives. As analytical demands continue to grow, laboratories need innovative technologies that enhance productivity without compromising data quality or environmental responsibility.</strong></p><p>Join us to explore how the SCIEX Novus V55 System is ushering in a new era of sustainable high-performance mass spectrometry. Designed to maximize laboratory efficiency, the Novus V55 System enables faster quantitative workflows, increased sample throughput, and outstanding analytical performance, while reducing energy consumption and cooling requirements. Discover how you can achieve more with less—boosting productivity, lowering operational costs, and advancing your sustainability goals without sacrificing performance.</p><h4><strong>In this webinar, you will learn:</strong></h4><ul><li>Learn how to scale quantitative workflows to 1,000 MRMs/sec—boosting throughput without compromising data quality&nbsp;</li><li>Discover how to increase sample throughput by ~33% while maintaining sensitivity and reproducibility.</li><li>See how to reduce lab operating costs with up to 40% lower energy and cooling requirements</li></ul><blockquote><p><strong>Presenter: </strong>Aman Sharma (Sales Development Manager)</p></blockquote></div></div></div>

SCIEX: More with less - The new era of sustainable high-performance mass spectrometry

More with less: The new era of sustainable high-performance mass spectrometry

Discover the SCIEX novus V55 system. Learn how aeMRM technology and a 35% smaller footprint deliver sustainable, high-throughput LC-MS/MS

SCIEX novus V55: Sustainable High-Performance MS

<div><h4><strong>Unlock the Power of Full-Spectrum Flow Cytometry</strong></h4><p><strong>A two-part masterclass designed to help you understand, design, and apply high-dimensional flow cytometry workflows across immunology, oncology, and vaccine research.</strong></p><h5><strong>Session 2: Designing and Analysis of Spectral Flow Experiments</strong></h5><ul><li><strong>Key Advantages of Spectral Technology. </strong>Learn how spectral systems enable higher multiplexing, improved resolution, and enhanced flexibility in panel design for complex experiments.</li><li><strong>Workflow of Spectral Flow Cytometry. </strong>Step through the complete experimental journey—from panel design and sample preparation to acquisition and interpretation of high-dimensional data.</li><li><strong>Unmixing and Data Analysis Strategies. </strong>Gain insights into spectral unmixing principles and advanced analytical approaches that transform raw data into meaningful biological interpretation.</li></ul><h5><strong>Why Attend?</strong></h5><ul><li>Move beyond conventional flow limitations</li><li>Design high-dimensional experiments confidently</li><li>Learn real-world applications</li><li>Interact with flow cytometry experts</li></ul><blockquote><p><strong>Presenter:</strong> Dr. Hemant Agrawal (Director, Flowcytometry Solutions Pvt. Ltd., India)</p><p>Flow cytometry educationalist and global trainer with 15+ years of experience. Conducted 80+ onsite and 40+ online workshops worldwide. An active member of ISAC (International Society for Advancement of Cytometry) task forces, Dr. Agrawal is widely recognized for advancing cytometry education globally and has been an invited faculty at prestigious Indo-US Cytometry Workshops.</p></blockquote><blockquote><p><strong>Presenter:</strong> Dr. Saket Siddharth (Field Application Scientist – Flowcytometry, Agilent Technologies)</p><p>Saket Siddharth is a Flow Cytometry and Cell Analysis specialist with over nine years of experience spanning clinical cytometry, spectral cell sorting, and advanced multicolor panel design. He holds a Ph.D. from the Helmholtz Centre for Infection Research, Brunswick, Germany, and has developed strong expertise across antibody development, high-throughput screening, and assay validation for translational and research applications.</p></blockquote></div>

Agilent Technologies: Spectral Flow Cytometry Masterclass - Session 2

Spectral Flow Cytometry Masterclass - Session 2

Learn high-dimensional spectral flow cytometry workflows with Cytek. Master panel design, sample prep, and advanced spectral unmixing strategies

Spectral Flow Cytometry Masterclass

<p><strong>As materials become increasingly sophisticated, understanding their optical properties is essential for driving innovation, improving product performance, and ensuring quality. Whether developing anti-reflective coatings, optimising solar cell efficiency, designing specialty glass, or researching next-generation materials, accurate optical characterisation is a critical part of the workflow.</strong></p><p>Join us for this webinar to discover how the Agilent UV-Vis-NIR spectrophotometer enables researchers and industry professionals to measure and characterise a broad range of optical properties across diverse sample types and applications.</p><p>The webinar will showcase measurement techniques for transmission, reflectance, diffuse reflectance, and angular measurements, highlighting how the Agilent UV-Vis-NIR platform delivers reliable and reproducible data for both research and industrial applications.</p><h4><strong>Why Attend?</strong></h4><p><strong>In this session, you will learn:</strong></p><ul><li>How the Agilent UV-Vis-NIR can be used to characterise thin films, coatings, solar materials, and glass.</li><li>Techniques for measuring transmission, reflectance, and diffuse reflectance with confidence.</li><li>Methods for determining film thickness and evaluating optical performance.</li><li>How specialised accessories expand measurement capabilities for challenging samples.</li><li>Best practices for obtaining accurate, reproducible results across a variety of applications.</li><li>Real-world examples demonstrating how optical measurements can accelerate research and product development.</li></ul><h4><strong>Who Should Attend?</strong></h4><p><strong>This webinar is designed for:</strong></p><ul><li><strong>Academic Researchers and Students</strong><ul><li>Researchers in materials science, physics, chemistry, and engineering.</li><li>Scientists investigating thin films, nanomaterials, optical materials, and photonic devices.</li><li>Graduate students and postdoctoral researchers seeking advanced optical characterisation techniques.</li></ul></li><li><strong>Solar and Photovoltaics</strong><ul><li>Scientists and engineers developing solar cells and photovoltaic materials.</li><li>Researchers evaluating anti-reflective coatings and light management strategies.</li><li>Teams working to improve solar cell efficiency through optical optimisation.</li></ul></li><li><strong>Glass and Coatings Industries</strong><ul><li>Manufacturers of architectural, automotive, and specialty glass.</li><li>Researchers developing low-emissivity and anti-reflective coatings.</li><li>Quality control and R&amp;D professionals responsible for optical performance testing.</li></ul></li><li><strong>Advanced Materials and Industrial R&amp;D</strong><ul><li>Thin film and semiconductor researchers.</li><li>Optical coating manufacturers.</li><li>Scientists working with displays, sensors, filters, and advanced functional materials.</li><li>Analytical laboratories requiring precise optical characterisation.</li></ul></li></ul><h5><strong>Featured Applications</strong></h5><ul><li>Thin film and multilayer coating analysis</li><li>Anti-reflective and optical coating characterisation</li><li>Solar cell and photovoltaic material evaluation</li><li>Optical filter transmission and blocking measurements</li><li>Architectural and specialty glass analysis</li><li>Reflectance measurements at varying angles of incidence</li><li>Film thickness determination</li><li>Diffuse reflectance measurements of scattering materials</li><li>Optical characterisation of emerging materials in academia and industry</li></ul><p>Discover how the Agilent UV-Vis-NIR platform combines exceptional optical performance, flexible sampling accessories, and intuitive workflows to provide the insights needed to advance research, optimise products, and solve challenging analytical problems.</p><blockquote><p><strong>Presenter: </strong>Mr. Rajwar Chandra (Product Specialist - Spectroscopy, Agilent Technologies)</p><p>Chandra Rajwar is a Product &amp; Market Specialist with over 20 years of experience in Molecular Spectroscopy products and analytical instrumentation. He specializes in UV-Vis, FTIR, Raman, and related spectroscopy solutions, supporting customers with application development, workflow optimization, and analytical excellence across pharmaceutical, chemical, environmental, and research industries.</p></blockquote><blockquote><p><strong>Presenter: </strong>Ms. Vijaya Jyothi (Product Specialist - Spectroscopy, Agilent Technologies India Pvt. Ltd.)</p><p>Vijaya Jyothi is a seasoned product specialist at Agilent Technologies. She manages the spectroscopy division, having extensive expertise in spectroscopy applications across diverse industries, offering deep insights and solutions tailored to varied analytical needs.</p></blockquote>

Agilent Technologies: Characterising Advanced Materials with the Agilent UV-Vis-NIR - From Thin Films and Solar Cells to Glass and Optical Coatings

Characterising Advanced Materials with the Agilent UV-Vis-NIR: From Thin Films and Solar Cells to Glass and Optical Coatings

Characterize thin films, solar cells, and coatings with Agilent UV-Vis-NIR. Master reflectance, transmission, and angular measurement workflows

Materials Characterization with Agilent UV-Vis-NIR

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>As laboratories grow, managing data across multiple instruments, users, and locations becomes increasingly complex. If you are looking to improve efficiency, strengthen data integrity, simplify administration, and support regulatory compliance through centralized data management and standardized workflows, you need to join this webinar.</strong></p><p>Are you currently using software on individual workstations? Do you have multiple software packages to run different vendor instruments? Discover how deploying <strong>Thermo Scientific™ Chromeleon™ software</strong> can help you. This session will explore how transitioning to a networked deployment can deliver greater scalability, enhanced collaboration, streamlined management, and a foundation for future digital transformation. Attendees will gain practical insights into the business and operational benefits of Chromeleon software across a wide range of industries.</p><h4><strong>Who should attend?</strong></h4><ul><li>Current Chromeleon workstation users&nbsp;</li><li>Those running multiple software packages looking to reduce training efforts</li><li>Laboratory managers and supervisors</li><li>Chromatography and analytical scientists</li><li>Laboratory IT and informatics professionals</li><li>Quality assurance and compliance personnel</li><li>Organizations looking to improve operational efficiency, data management, and scalability across their laboratories</li></ul><blockquote><p><strong>Presenter: </strong>Kimy Young (Senior Manager, Software Product Specialists, Thermo Fisher Scientific)</p><p>Kimy Young is the Senior Manager of software product specialists at Thermo Fisher Scientific. She has been with Thermo Fisher since November 2015. Her background includes administration of Chromeleon CDS, laboratory information management systems (LIMS), Quality Assurance (QA), and IT projects.</p><p><strong>Presenter: </strong>Juan Carmona (Chromeleon CDS Specialist, Thermo Fisher Scientific)</p><p>Juan Carmona is a Chromeleon Specialist at Thermo Fisher Scientific based out of Pflugerville, TX. He has been with Thermo Fisher Scientific for over 15 years. At Thermo Fisher Scientific, he is currently focusing on expanding the customer base using Chromeleon CDS for small networks and enterprise deployments. Prior to joining this group, he was part of the GC/GCMS Center of Excellence team providing support for the product line.</p></blockquote></div></div></div>

Thermo Fisher Scientific: Chromeleon software webinar series

Drive lab collaboration and efficiency with a networked chromatography and mass spectrometry data system

Discover how Chromeleon CDS network deployment improves data management, compliance, scalability, and workflow efficiency across analytical laboratories.

Networked chromatography and mass spectrometry data system

<h4><strong>LC Coffee Breaks Free Webinar Series</strong></h4><p>Each episode focuses on answering a specific challenge faced by chromatographers, helping you improve efficiency, solve problems faster, and stay up to date with the latest trends in Liquid Chromatography.</p><h4><strong>Episode 1</strong></h4><h5><strong>Mastering Overpressure - Prevention and Solutions that Work</strong></h5><h4><strong>What will you learn</strong></h4><ul><li>Overpressure is a common LC challenge that can lead to downtime and unreliable results. Learn or review how to:</li><li>Identify key causes and solve them</li><li>Prevent issues in practical ways</li></ul><h4><strong>Why you should attend</strong></h4><p>Get practical, users insights you can immediately apply in your daily LC laboratory work.&nbsp;<br>In just a short coffee-break session, you'll gain valuable tips on troubleshooting, method development, method transfer, technology updates, column chemistries, and real-world applications.</p><blockquote><p><strong>Speaker: </strong>Walter Migliaccio (Sales Application Chemist, Waters)</p></blockquote>

LC Coffee Breaks: Mastering Overpressure - Prevention and Solutions that Work

Learn how to identify, solve, and prevent LC system overpressure. Join Waters' short webinar to eliminate downtime and keep your analysis running