<p><strong>Next 14 days the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p>
<blockquote>
<h4><a href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in more than <strong>2 000 GC, LC nad MS webinars</strong></p>
</blockquote>
<h5><strong>1. Shimadzu Corporation: Understanding LC Columns - Difference in Column Types and Phases</strong></h5>
<ul>
<li>Th, 12.1.2023, 08:00 (CET)</li>
</ul>
<p>We will introduce the different mode of separation in liquid chromatography including reversed phase, normal phase and HILIC.</p>
<h5><strong>2. Agilent Technologies: Common UV-Vis Questions Answered</strong></h5>
<ul>
<li>Th, 12.1.2023, 20:00 (CET)</li>
</ul>
<p>Join us in this webinar where we will discuss some of the most common questions for UV-VIS data collection.</p>
<h5><strong>3. Agilent Technologies: Picking the Right UV-Vis-NIR For Me: What Specs Do I Need?</strong></h5>
<ul>
<li>Fr, 13.1.2023, 19:00 (CET)</li>
</ul>
<p>Key performance differentiators between UV-VIS-NIR spectrometers as well as the impact that these have on measurement capabilities.</p>
<h5><strong>4. Agilent Technologies: Agilent Oligonucleotide Insight Days (Day 1)</strong></h5>
<ul>
<li>We, 18.1.2023, 10:00 (CET)</li>
</ul>
<p>Taking A Deeper Dive into Oligonucleotide Analysis</p>
<h5><strong>5. Agilent Technologies: Scale Up from Analytical to Prep with Agilent Prep LC Columns</strong></h5>
<ul>
<li>We, 18.1.2023, 11:00 (CET)</li>
</ul>
<p>Become familiar with the analytical to preparative chromatography workflow and learn strategies to efficiently develop methods for purification success.</p>
<h5><strong>6. Agilent Technologies: Sample Preparation for Improved LC Bio Separations</strong></h5>
<ul>
<li>We, 18.1.2023, 17:00 (CET)</li>
</ul>
<p>In this discussion we will look at some common bio sample preparation techniques, from solvent exchanges to solid phase extractions.</p>
<h5><strong>7. Agilent Technologies: Agilent Oligonucleotide Insight Days (Day 2)</strong></h5>
<ul>
<li>Th, 19.1.2023, 10:00 (CET)</li>
</ul>
<p>Taking A Deeper Dive into Oligonucleotide Analysis</p>
<h5><strong>8. Evosep Biosystems: A beginner’s guide to Evosep</strong></h5>
<ul>
<li>Th, 19.1.2023, 16:00 (CET)</li>
</ul>
<p>The Evosep One is a plug-and-play standardized platform designed for robustness and high throughput.</p>
<h5><strong>9. Waters Corporation: A Guide to Ensuring Your Data Is Secure and Available from Creation Thru the Full Mandated Retention Period</strong></h5>
<ul>
<li>Th, 19.1.2023, 16:00 (CET)</li>
</ul>
<p>As always, don’t forget to bring your Empower questions for this exclusive opportunity to ask our experts anything about Empower Software.</p>
<h5><strong>10. C&amp;EN/Agilent Technologies: Recent Advances in Oligo Purity and Sequence Determination by LCMS</strong></h5>
<ul>
<li>Th, 19.1.2023, 17:00 (CET)</li>
</ul>
<p>In this work, we present novel, automated, and integrated software to support oligos workflows using LC HRAM MS instruments.</p>


Webinars LabRulezLCMS Week 2-3/2023

<p><strong>Experienced application specialists and experts in the field of liquid phase separations bring you webinars/lectures and give you invaluable knowledge on how to work with liquid chromatographs.</strong></p>
<p>In the world&#39;s largest database of these <strong>separation techniques</strong> and <strong>mass spectrometry</strong> webinars, you can <strong>search</strong> and <strong>filter</strong> over 2000 webinars from 2020-2023 and watch them anytime from record.</p>
<p>The PDF lectures themselves are also available for selected recordings. Check out the 2022 Liquid Chromatography Tips and Tricks topics like:</p>
<ul>
<li>HPLC hardware <strong>troubleshooting</strong></li>
<li><strong>Preventive</strong> and <strong>routine maintenance</strong></li>
<li><strong>Peak shape</strong></li>
<li><strong>Development</strong> and <strong>optimization of HPLC methods</strong></li>
<li>Most Common <strong>Troubleshooting Mistakes</strong></li>
<li><strong>Where to look for a problem</strong> in your HPLC?</li>
<li><strong>Method transfer</strong></li>
<li><strong>Properties of analytes</strong> and method development</li>
<li><strong>SEC</strong> and <strong>IEX</strong> separation</li>
<li><strong>Modernization of HPLC methods</strong></li>
<li><strong>Contamination</strong> in HPLC</li>
<li><strong>10 most common mistakes</strong> in method development</li>
<li><strong>HILIC</strong> - why and where to use?</li>
</ul>
<blockquote>
<p>💡 <a href="https://lcms.labrulez.com/webinars?tags=24-15"><strong>Recordings of all lectures are available for free in the Webinars section under the filter HPLC + Tips &amp; Tricks</strong></a></p>
</blockquote>
<h5><strong>1. Restek Corporation: LC Hardware Troubleshooting part 2</strong></h5>
<ul>
<li>RECORD | Already taken place Th, 8.12.2022</li>
</ul>
<p>We will discuss how problems with your instrument may affect your chromatographic separations.</p>
<h5><strong>2. Restek Corporation: LC Hardware Troubleshooting part 1</strong></h5>
<ul>
<li>RECORD | Already taken place Th, 24.11.2022</li>
</ul>
<p>In this presentation, we’ll be walking you through an overview of the processes involved with basic HPLC instrumentation.</p>
<h5><strong>3. Agilent Technologies: How to Keep a Good Thing Going: Preventive and Routine Maintenance for Your HPLC System</strong></h5>
<ul>
<li>RECORD | Already taken place Tu, 8.11.2022</li>
</ul>
<p>The goal of this talk is to lay a strong and broad foundation from which to build a better understanding of your own HPLC systems and their specific maintenance needs.</p>
<h5><strong>4. Phenomenex: Pirates of Chromatography: Tales of Sharp Peaks</strong></h5>
<ul>
<li>RECORD | Already taken place Th, 13.10.2022</li>
</ul>
<p>Topics: Signal to noise improvement, Unknown/Ghost/Carryover Peaks, No Peaks, Split peaks/Fronting peaks/Double peaks, Negative peaks, Peak Sequence change, Irreproducible peak heights and peak areas.</p>
<h5><strong>5. Phenomenex: Analytical Method Development for Oligonucleotide analysis</strong></h5>
<ul>
<li>RECORD | Already taken place We, 20.7.2022</li>
</ul>
<p>Primer on Oligonucleotide &amp; chromatographic challenges. Method Development consideration by LC. Mobile phase composition Impact on sensitivity. The impacts on metal cations on LC MS methods for Oligos.</p>
<h5><strong>6. Phenomenex: 5 Common LC Troubleshooting Mistakes and What to Do Instead</strong></h5>
<ul>
<li>RECORD | Already taken place Th, 7.7.2022</li>
</ul>
<p>Understanding chromatographic Interactions. Identifying Sytem/method/column related issues. Choosing right mobile phase/column. Proper column washing and storage conditions.</p>
<h5><strong>7. Agilent Technologies: From Instrument to Column: Tracking down the Problem</strong></h5>
<ul>
<li>RECORD | Already taken place Th, 26.5.2022</li>
</ul>
<p>In this webinar, we will work through troubleshooting strategies to help find the source of the problem.</p>
<h5><strong>8. Thermo Fisher Scientific: HPLC Method Transfer: A CDMO perspective</strong></h5>
<ul>
<li>RECORD | Already taken place Th, 19.5.2022</li>
</ul>
<p>We will share key learnings, feedback and best practices for transferring methods from competitive instruments and developing new ones onto the Vanquish liquid chromatography platform.</p>
<h5><strong>9. VWR: Understanding analyte physicochemical properties and their value in LC method development</strong></h5>
<ul>
<li>RECORD | Already taken place Th, 12.5.2022</li>
</ul>
<p>This webinar will review the range of analyte properties that are important to consider when developing methods.</p>
<blockquote>
<p>💡 <a href="https://lcms.labrulez.com/library?publicationTypeItems=2-7-5-4&amp;search=troubleshooting"><strong>Literature focused on solving problems in liquid chromatography (Troubleshooting) in the LabRulezLCMS library</strong></a></p>
</blockquote>
<h5><strong>10. Agilent Technologies: SEC and IEX for Biomolecules: Column Selection and Troubleshooting</strong></h5>
<ul>
<li>RECORD | Already taken place Th, 28.4.2022</li>
</ul>
<p>Size Exclusion and Ion Exchange are typically run in non-denaturing conditions. That’s one of the reasons they are the two most common types of HPLC used for biomolecules.</p>
<h5><strong>11. Agilent Technologies: ChromTalk Episode 14: Tips &amp; Tricks In Modernizing Methods For Efficient &amp; Productive Analysis</strong></h5>
<ul>
<li>RECORD | Already taken place We, 20.4.2022</li>
</ul>
<p>Modernizing traditional methods = Efficient &amp; Productive Analysis.</p>
<h5><strong>12. Phenomenex: Troubleshooting LC System Contamination</strong></h5>
<ul>
<li>RECORD | Already taken place Tu, 5.4.2022</li>
</ul>
<p>3 Topics: General steps on HPLC troubleshooting &amp; End of column natural lifetime &amp; How to protect your column &amp; Case Study on LC system contamination troubleshooting.</p>
<h5><strong>13. Agilent Technologies: Top 10 Fails When Developing a HPLC Method</strong></h5>
<ul>
<li>RECORD | Already taken place Tu, 22.3.2022</li>
</ul>
<p>In this talk we review the list of our top 10 “gotchas”. Let’s point them out, understand their significance, and remember to avoid them in the future.</p>
<h5><strong>14. Agilent Technologies: Enhance your Lab Productivity School Series of LC Advanced Chapter</strong></h5>
<ul>
<li>RECORD | Already taken place We, 16.3.2022</li>
</ul>
<p>Webinar topics: Introduction to Method development and Agilent solutions; Services for entire Lab from Simplification to optimization; Advanced Troubleshooting Tips &amp; Tricks for Agilent HPLC.</p>
<h5><strong>15. Phenomenex: Essential LC Method Development</strong></h5>
<ul>
<li>RECORD | Already taken place Tu, 8.3.2022</li>
</ul>
<p>We will cover topics like: Chromatographic interactions, The role of mass spec, HPLC column selection, Mobile phase considerations for LC-MS, Optimizing gradient, flow rate, and injection parameters.</p>
<h5><strong>16. Phenomenex: HPLC System Optimization</strong></h5>
<ul>
<li>RECORD | Already taken place Tu, 25.1.2022</li>
</ul>
<p>Learn how to optimize your HPLC system to enhance performance by minimizing extra column volume and how to easily ensure zero-dead volume connections throughout your HPLC system.</p>
<h5><strong>17. Agilent Technologies: HILIC Chromatography: When and How?</strong></h5>
<ul>
<li>RECORD | Already taken place Tu, 25.1.2022</li>
</ul>
<p>When to use HILIC and how to approach HILIC method development? We will go over column selection, mobile phase considerations, detection, tips and tricks for column care, and troubleshooting.</p>


Tips & Tricks in Liquid Chromatography (HPLC Webinars 2022)

<p><strong>Next 14 days the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p>
<blockquote>
<h4><a href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in more than <strong>2 000 GC, LC nad MS webinars</strong></p>
</blockquote>
<h5><strong>1. SelectScience/Tecan: Automated proteomics sample prep: Realizing the need for higher throughput, robustness, and standardization</strong></h5>
<ul>
<li>Mo, 30.1.2023, 17:00 (CET)</li>
</ul>
<p>We will share how to use the affordable, small-footprint A200 and S-Trap 96-well plates to quickly and easily prepare samples for proteomics analysis without further method development.</p>
<h5><strong>2. Phenomenex: Novel Oligonucleotide Sample Clean-up and Method Optimizations</strong></h5>
<ul>
<li>Tu, 31.1.2023, 19:00 (CET)</li>
</ul>
<p>Sample preparation strategies for synthetic oligonucleotides, including how to adjust experimental design depending on the oligo and sample matrix.</p>
<h5><strong>3. Agilent Technologies: Cannabis - Potency with LC/UV</strong></h5>
<ul>
<li>We, 1.2.2023, 20:00 (CET)</li>
</ul>
<p>Join Agilent application scientists as they demonstrate our OpenLab CDS and MassHunter software for cannabis workflows.</p>
<h5><strong>4. Axion Labs and Training Institute: Analyze This! Live Sample Analysis from raw material to final report</strong></h5>
<ul>
<li>Th, 2.2.2023, 20:00 (CET)</li>
</ul>
<p>Join us for our 2023 live-labinar series where we will analyze real samples by HPLC and GC.</p>
<h5><strong>5. Agilent Technologies: Cannabis - Potency with LC/MS</strong></h5>
<ul>
<li>Th, 2.2.2023, 20:00 (CET)</li>
</ul>
<p>Join Agilent application scientists as they demonstrate our OpenLab CDS and MassHunter software for cannabis workflows.</p>
<h5><strong>6. Phenomenex: SEC-nHRMS for the Characterization of mAbs</strong></h5>
<ul>
<li>Tu, 7.2.2023, 19:00 (CET)</li>
</ul>
<p>Receive a demonstration of how non-denaturing SEC-Native MS can be leveraged to streamline mAb characterization, including methods for the digestion of mAbs.</p>
<h5><strong>7. Phenomenex: Harmonisation of Ph.Eur. 2.2.46 and USP 621</strong></h5>
<ul>
<li>Th, 9.2.2023, 05:30 (CET)</li>
</ul>
<p>Guidance to making Adjustments to chromatographic methods...</p>
<h5><strong>8. Agilent Technologies: Let&#39;s Talk Polar Pesticides</strong></h5>
<ul>
<li>Th, 9.2.2023, 06:30 (CET)</li>
</ul>
<p>During this Deminar, our speakers will take you through the various aspects of the Polar pesticides problem, from regulatory guidelines to workflow solutions, live from Agilent Lab.</p>
<h5><strong>9. Waters Corporation: CHROMATOGRAPHY CONCEPTS FOR PEPTIDES AND PROTEINS</strong></h5>
<ul>
<li>Th, 9.2.2023, 16:30 (CET)</li>
</ul>
<p>This webinar series will cover the foundations of chromatography for the separation and analysis of peptides and proteins.</p>


Webinars LabRulezLCMS Week 5-6/2023

<p><strong>Next 14 days the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p>
<blockquote>
<h4><a href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in more than <strong>2 000 GC, LC nad MS webinars</strong></p>
</blockquote>
<h5><strong>1. Phenomenex: SEC-nHRMS for the Characterization of mAbs</strong></h5>
<ul>
<li>Tu, 7.2.2023, 19:00 (CET)</li>
</ul>
<p>Receive a demonstration of how non-denaturing SEC-Native MS can be leveraged to streamline mAb characterization, including methods for the digestion of mAbs.</p>
<h5><strong>2. Phenomenex: Harmonisation of Ph.Eur. 2.2.46 and USP 621</strong></h5>
<ul>
<li>Th, 9.2.2023, 05:30 (CET)</li>
</ul>
<p>Guidance to making Adjustments to chromatographic methods...</p>
<h5><strong>3. Agilent Technologies: Let&#39;s Talk Polar Pesticides</strong></h5>
<ul>
<li>Th, 9.2.2023, 06:30 (CET)</li>
</ul>
<p>During this Deminar, our speakers will take you through the various aspects of the Polar pesticides problem, from regulatory guidelines to workflow solutions, live from Agilent Lab.</p>
<h5><strong>4. Waters Corporation: CHROMATOGRAPHY CONCEPTS FOR PEPTIDES AND PROTEINS</strong></h5>
<ul>
<li>Th, 9.2.2023, 16:30 (CET)</li>
</ul>
<p>This webinar series will cover the foundations of chromatography for the separation and analysis of peptides and proteins.</p>
<h5><strong>5. Shimadzu Corporation: Introducing the latest version Lab-at-a-glance powered by LabSolutions BiX</strong></h5>
<ul>
<li>Tu, 14.2.2023, 07:00 (CET)</li>
</ul>
<p>LabSolutions BiX enables the monitoring of the Live Status of laboratory activities, the efficiency of laboratory users, instrument utilization, and other new features...</p>
<h5><strong>6. Separation Science: Computerized System Validation: GAMP 5 2nd Edition, What You Need to Know</strong></h5>
<ul>
<li>We, 15.2.2023, 16:00 (CET)</li>
</ul>
<p>We shall take a look at the contents of the long awaited GAMP 5 Version 2 release to examine what has truly changed since the Version 1 release, with special focus on Pharma, BioPharma, and Biotech industries.</p>
<h5><strong>7. Thermo Fisher Scientific: Proteome Discoverer XlinkXWorkshop</strong></h5>
<ul>
<li>We, 15.2.2023, 16:00 (CET)</li>
</ul>
<p>An online Proteome Discoverer crosslinking training workshop delivered, designed to get novice/intermediate users up to speed with the PD 3.0 (SP1) software package.</p>
<h5><strong>8. Phenomenex: Analytical BioSolutions for Therapeutic Oligonucleotides</strong></h5>
<ul>
<li>Th, 16.2.2023, 05:30 (CET)</li>
</ul>
<p>Reversed Phase-Ion Pair LC for Oligos - Challenges and Optimization...</p>
<h5><strong>9. Waters Corporation: PRINCIPLES OF SIZE EXCLUSION CHROMATOGRAPHY: OPTIMIZING PARTICLE SIZE, PORE SIZE, AND COLUMN DIMENSIONS</strong></h5>
<ul>
<li>Th, 16.2.2023, 16:30 (CET)</li>
</ul>
<p>This webinar series will cover the foundations of chromatography for the separation and analysis of peptides and proteins.</p>
<h5><strong>10. SelectScience/Agilent Technologies: Analysis of oligonucleotides by accurate mass LC/MS: Sequencing and impurity analysis to support development at Arrowhead Pharmaceuticals</strong></h5>
<ul>
<li>Th, 16.2.2023, 17:00 (CET)</li>
</ul>
<p>Learn from a practical demonstration about a case where LC/MS oligonucleotides analyses have been undertaken to confirm the molecular sequence, as well as to understand process impurities and degradants.</p>


Webinars LabRulezLCMS Week 6-7/2023

<p><strong>After many heartfelt speeches the organizing team was rewarded with small gifts.</strong></p>
<p><strong>The ESAS organizing team would like to thank all the participants of the conference and look forward to the next conference, where we will all meet again in good health and good spirits.</strong></p>
<blockquote>
<p>💡💡💡 <a href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ESAS_2022_BOOK_OF_ABSTRACTS_a222376ad0/ESAS-2022-BOOK-OF-ABSTRACTS.pdf"><strong>BOOK OF ABSTRACTS ESAS-CSSC 2022</strong></a></p>
</blockquote>
<h3><strong>Programme friday 9th of September 2022</strong></h3>
<h4><strong>LASER INDUCED BREAKDOWN SPECTROMETRY</strong></h4>
<ul>
<li>(Hall P31) CHAIR: GALBÁCS</li>
</ul>
<h5><strong>9:00 – 9:30 Complementarity of laser-induced breakdown spectroscopy and laser ablation inductively coupled plasma mass spectrometry in cancer tissues analysis</strong></h5>
<ul>
<li>IL 28: P. POŘÍZKA</li>
</ul>
<p>It has been shown that cancerous tissues change the chemical composition of cells <strong>Error! Reference source not found.</strong> These changes in elemental composition can be observed using Laser-Induced Breakdown Spectroscopy (LIBS) or Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS), where imaging of biotic (e.g., C, P, Ca, Mg) and trace (e.g., Zn, Cu) elements provides information about the distribution of soft tissue elements and, consequently, the location of cancerous tissue.</p>
<p>This paper deals with a correlative study using LIBS and LA-ICP-MS in a sample of healthy human skin, four samples of malignant tumours (squamous cell carcinoma, malignant melanoma, basal cell carcinoma, and epithelioid angiosarcoma), and one sample of a benign tumour (pigmented nevus). Analysis was performed using both techniques for all these samples, and spatial distributions of selected elements were constructed. This work aims to show the potential of correlation of data obtained from both analytical methods, which could be used for the possible diagnosis of cancer as a complementary technique to classical histological examination.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Complementarity_of_laser_induced_breakdown_spectroscopy_and_laser_ablation_inductively_coupled_plasma_mass_spectrometry_in_cancer_tissues_analysis_P_PORIZKA_c2d66f4b01/SSJMM-Complementarity-of-laser-induced-breakdown-spectroscopy-and-laser-ablation-inductively-coupled-plasma-mass-spectrometry-in-cancer-tissues-analysis-(P.-PORIZKA).jpg" alt="SSJMM: Complementarity of laser-induced breakdown spectroscopy and laser ablation inductively coupled plasma mass spectrometry in cancer tissues analysis (P. POŘÍZKA)"/></p>
<h5><strong>9:30 – 10:00 Understanding the correlation of LIBS and acoustic measurements of rock and soil found in the traverse of Perseverance rover across the Jezero crater, Mars</strong></h5>
<ul>
<li>IL 29: J. LASERNA</li>
</ul>
<p>The SuperCam instrument of the NASA MARS 2020 Perseverance rover combines a suite of atomic and molecular spectroscopies intended for an extensive description of rocks, soils and minerals in the surroundings of the landing site of the mission – the Jezero crater. The microphone installed on the SuperCam instrument allows the acquisition of acoustic signals resulting from the expansion of laser-induced plasmas towards the atmosphere. Apart from being affected by the propagation characteristics of the Mars atmosphere, the acoustic signal has an additional component related to the properties of the target including surface morphology, hardness, deformation parameters, and elasticity, among others. This information is currently being investigated as a complementary resource for characterization of the ablated material and may well supplement the LIBS data gathered from coincident laser shots. This talk will present SuperCam acoustic data of rocks and minerals found in the traverse of the Perseverance rover and will discuss its correlation with LIBS spectra.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Understanding_the_correlation_of_LIBS_and_acoustic_measurements_of_rock_and_soil_found_in_the_traverse_of_Perseverance_rover_across_the_Jezero_crater_Mars_J_LASERNA_601a7a5b62/SSJMM-Understanding-the-correlation-of-LIBS-and-acoustic-measurements-of-rock-and-soil-found-in-the-traverse-of-Perseverance-rover-across-the-Jezero-crater-Mars-(J.-LASERNA).jpg" alt="SSJMM: Understanding the correlation of LIBS and acoustic measurements of rock and soil found in the traverse of Perseverance rover across the Jezero crater, Mars (J. LASERNA)"/></p>
<h5><strong>10:00 – 10:20 Laser induced breakdown spectroscopy imaging of uranium ores</strong></h5>
<ul>
<li>OL 61: K. NOVOTNÝ</li>
</ul>
<p>Laser-induced breakdown spectroscopy (LIBS) was applied to create images revealing the distribution and possible migration of elements in samples of uranium ore. Compared to SEM or LA-ICP-MS, fast LIBS scanning made it possible to perform analysis across the big sample area containing different mineral phases of uranium ores including associated minerals. However, the imaging of some associated elements is due to rich spectra and low contents still challenging. Moreover, compromise conditions have to be often set to reach the required spatial resolution, speed of scanning and sensitivity. Generally, higher resolution is paid for by the loss of sensitivity and vice versa. Nevertheless, there are some possibilities for improvement in both instrumentation and spectral data processing. Different effects such as the role of the introduction of noble gas, influence of laser wavelength or double pulse methods will be discussed.</p>
<p>The investigated geological samples represent U-mineralisation from a former deep uranium mine. Obtained elemental images help to reveal and distinguish different phases such as massive uraninite and carbonate vein or metasomatite. Additionally, the signal correlation of some elements (correlation between different emission lines) helps with the identification of other associated minerals.</p>
<h5><strong>10:20 – 10:40 LIBS applications of online monitoring and 2D/3D mappings for advanced control of industrial processes</strong></h5>
<ul>
<li>OL 62: Y. DEGUCHI</li>
</ul>
<p>Advanced monitoring and control methods are significant in the industrial processes. Laserinduced breakdown spectroscopy (LIBS) is an analytical detection technique based on atomic emission spectroscopy to measure the elemental composition, which has been widely applied in various fields (1). In this study, LIBS applications of online monitoring and 2D/3D mappings were demonstrated for advanced control of industrial processes.</p>
<p>A collinear long and short DP-LIBS method (LS-DP-LIBS) was developed to improve the detection ability and measurement accuracy by the control of the plasma cooling process using the long pulse-width laser radiation (2). The plasma generated by the short pulse-width laser is stabilized and maintained at high temperature during the plasma cooling process by long pulsewidth laser radiation. C, Al, Si, S, Ti, Cr, Ni, Cu, Nb, Mo, Mn, and B concentration measurements in molten steel samples were performed using LS-DP-LIBS. It demonstrates the feasibility of multi-element concentration measurements in iron and steel making processes and this will lead to the advanced monitoring and control methods in these processes.</p>
<p>The analysis of elemental composition distribution is indispensable to ensure the quality of various materials production. In this regard, 2D/3D mapping techniques using LIBS are widely used in various fields. In many LIBS studies, lasers with ns pulse widths are used, and the spatial resolution of 2D LIBS mapping is usually several to several tens of micrometers. In this study, a spatial resolution of 1 μm was achieved by using a laser with a pulse width of 9 ps. This LIBS mapping system consists of a picosecond laser, lens, spectrometer, ICMOS camera, and XYZ stage. The LIBS system was applied to steel and Li-ion battery electrodes for 2D elemental distribution analysis. The steel sample has a structure with Zn coating around the steel at the μm level, and this LIBS mapping system was able to detect the Zn distribution around the steel at the μm level. This result was in good agreement with the SEM-EDS measurement. LIBS has the advantage of elemental composition mapping without the need for high vacuum conditions and has many advantages when applied to industrial processes. In the future, the LIBS analysis speed is improved to 1 kHz and the LIBS system is utilized for elemental composition mapping in industrial processes.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_LIBS_applications_of_online_monitoring_and_2_D_3_D_mappings_for_advanced_control_of_industrial_processes_Y_DEGUCHI_267fd9abf7/SSJMM-LIBS-applications-of-online-monitoring-and-2D-3D-mappings-for-advanced-control-of-industrial-processes-(Y.-DEGUCHI).jpg" alt="SSJMM: LIBS applications of online monitoring and 2D-3D mappings for advanced control of industrial processes (Y. DEGUCHI)"/></p>
<h5><strong>10:40 – 11:10 COFFEE BREAK</strong></h5>
<ul>
<li>ATRIUM OF FACULTY OF SOCIAL STUDIES</li>
</ul>
<h4><strong>LASER INDUCED BREAKDOWN SPECTROMETRY</strong></h4>
<ul>
<li>(Hall P31) CHAIR: LASERNA</li>
</ul>
<h5><strong>11:10 – 11:40 Nanoparticles in plasma spectroscopy: detection and signal enhancement in gaseous, liquid and solid samples</strong></h5>
<ul>
<li>IL 30: G. GALBÁCS</li>
</ul>
<p>Nanoscience has advanced greatly in the last two decades. Due to their special optical, mechanical, magnetic and energetic properties, nanoparticles (NPs) are nowadays exploited in many industrial, scientific and medical fields. The continuous development of nanomaterials as well as their increasing presence in the environment and biological systems also necessitates the development of such analytical methods that are capable of the sensitive detection and characterization of NPs in various sample matrices. Such methods often built on the application of laser induced breakdown spectroscopy (LIBS) or single particle inductively coupled plasma mass spectrometry (spICP-MS). At the same time, plasma spectroscopy techniques – LIBS included – also can benefit from using NPs to enhance their analytical signals. Therefore the development of NPs and plasma spectroscopy are strongly intertwined fields.</p>
<p>In this contribution, some recent results of the research group of the author obtained using LIBS and spICP-MS methods will be presented. It will be demonstrated, how various characteristics (composition, concentration, structure, size distribution, porosity, aspect ratio, etc.) of inorganic NPs and nanocomposites dispersed in aqueous liquid samples can be assessed using novel spICP-MS methodologies. The LIBS detection and characterization of NPs suspended in a gas medium and occurring in plant samples will also be described. Results on LIBS signal enhancement effectuated with the application of NPs for gas, liquid and solid samples via the exploitation of plasmonic and electron field- or thermoemission mechanisms will also be presented.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Nanoparticles_in_plasma_spectroscopy_detection_and_signal_enhancement_in_gaseous_liquid_and_solid_samples_G_GALBACS_ee291fadbe/SSJMM-Nanoparticles-in-plasma-spectroscopy-detection-and-signal-enhancement-in-gaseous-liquid-and-solid-samples-(G.-GALBACS).jpg" alt="SSJMM: Nanoparticles in plasma spectroscopy - detection and signal enhancement in gaseous, liquid and solid samples (G. GALBÁCS)"/></p>
<h5><strong>11:40 – 12:10 Enhancing the sensitivity of laser-induced breakdown spectroscopy for the detection of nanoparticle-labeled cancerous tissues</strong></h5>
<ul>
<li>IL 31: J. KAISER</li>
</ul>
<p>Fluorescent labels, based on conjugates of antibodies with various nanoparticles, are popular because of their broad detection posibilities (plate readers, microscopes). However, fluorescence is a limiting factor in e.g. multiplexing; only a limited number of dyes can be detected due to the overlaps of dye spectra or optical filters. Thus, novel readout methods are necessary to overcome such limitations. Laser spectroscopy – namely Laser-Induced Breakdown Spectroscopy (LIBS) – is a prospective option in nanoparticle detection (1). LIBS provides superior performance in terms of throughput and repetition rate enabling large-scale elemental imaging in combination with high lateral resolution. In this talk, we will demonstrate the feasibility of LIBS as a readout method in immunochemical assays and imaging of cancer tissues (breast cancer) through the indirect detection of upconversion nanoparticles (UCNPs) (2). The LIBS scanning enabled detecting the characteristic elemental signature of yttrium as a principal constituent of UCNP, thus indirectly providing a reliable way to differentiate between HER2-positive BT-474 cells and HER2-negative MDA-MB-231 cells. The comparison of results with upconversion optical microscopy and luminescence intensity scanning confirmed that LIBS is a promising alternative for the readout of immunohistochemical samples. Moreover, we have deployed the collinear double-pulse arrangement for enhanced sensitivity and detection capability, Fig. 1.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Fig_1_Signal_of_Y_II_437_49_nm_spectral_line_enhanced_by_collinear_DP_arrangement_797a0de7ba/SSJMM-Fig.-1.-Signal-of-Y-II-437.49-nm-spectral-line-enhanced-by-collinear-DP-arrangement.jpg" alt="SSJMM: Fig. 1. Signal of Y II 437.49 nm spectral line enhanced by collinear DP arrangement"/></p>
<h5><strong>12:10 – 12:30 Polychromator ORCA ( Optimized Rowland Circle Alignment )</strong></h5>
<ul>
<li>OL 63: P. KOLEČKÁŘ</li>
</ul>
<p>The lecture will discuss a spectrometer that is competitive in ICP spectrometers to ECHELLE type spectrometers. The ECHELLE optical system is very often used in ICP spectrometers, which has its advantages (in particular, it is small in size), but also a number of disadvantages, especially the very variable spectral resolution.</p>
<p>The company SPECTRO A.I. Kleve, Germany uses Paschen-Runge type spectrometers in their manufactured instruments. This lecture discusses these spectrometers. Paschen-Runge spectrometers use the Rowland circle system. They are generally larger in size than ECHELLE spectrometers, but they have a number of advantages, among which the main ones include constant and uniform spectral resolution and smaller (weaker) scattered light than<br/>in ECHELLE spectrometers.</p>
<p>The Optimized Roland Circle Alignment Concept (ORCA), as SPECTRO AI calls its patented spectrometer system, is based on the Paschen-Runge spectrometer system.</p>
<p>In this system, the spectral resolution is determined only by the diameter of the Rowland circle and the dispersion of the grating used (number of scratches/1mm). The larger the diameter of the Rowland circle and the number of scratches of the dispersion grating, the better the spectral resolution. But this cannot be increased to infinity because the light intensity decreases with the square of the distance. At twice the distance, there is a fourfold decrease in light. Therefore, a reasonable compromise must be chosen.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Polychromator_ORCA_Optimized_Rowland_Circle_Alignment_P_KOLECKAR_9733685e45/SSJMM-Polychromator-ORCA-(-Optimized-Rowland-Circle-Alignment-)-(P.-KOLECKAR).jpg" alt="SSJMM: Polychromator ORCA ( Optimized Rowland Circle Alignment ) (P. KOLEČKÁŘ)"/></p>
<h5><strong>12:30 – 12:50 Aerosol analysis with laser-induced breakdown spectroscopy: Sampling approaches and recent applications</strong></h5>
<ul>
<li>OL 64: D. HAHN</li>
</ul>
<p>This talk describes how laser-induced breakdown spectroscopy (LIBS) became a viable analytical tool for aerosol analysis through advances in sampling and data analysis strategies, as well as deployment applications. The analysis of aerosols is a challenging task due to the wide variation of aerosol particles characteristics (e.g., source, size, chemical composition) and measurements requirements (e.g., chemical determination, sizing, number density), however, LIBS has demonstrated to perform well analyzing both the aerosol particles and the gaseous phase, specially, in harsh conditions where other techniques are simply not applicable. By coupling the point-to-point sampling nature of laser-induced plasmas with the discrete nature of aerosols particles and selective spectra analysis (i.e., Conditional Analysis) a considerable increase in LIBS sensitivity can be achieved. Finally, an overview of aerosol LIBS applications in industrial and laboratory setting are presented to showcase the versatility and in situ applicability of LIBS with recent data, including the applications of heavy metals high temperature effluents, gas and particulate emissions from battery cells at high temperature, and<br/>vapors and aerosols from molten salts.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SSJMM_Aerosol_analysis_with_laser_induced_breakdown_spectroscopy_Sampling_approaches_and_recent_applications_D_HAHN_6361ad3f57/SSJMM-Aerosol-analysis-with-laser-induced-breakdown-spectroscopy-Sampling-approaches-and-recent-applications-(D.-HAHN).jpg" alt="SSJMM: Aerosol analysis with laser-induced breakdown spectroscopy - Sampling approaches and recent applications (D. HAHN)"/></p>
<h5><strong>12:50 – 13:10 ESAS-CSSC 2022 CLOSING CEREMONY</strong></h5>
<h5><strong>13:10 – 14:30 LUNCH</strong></h5>
<ul>
<li>MU RECTORATE</li>
</ul>


ESAS-CSSC 2022 (Day 5)

<h3><strong>HOW TO WEIGH A MOLECULE?</strong></h3>
<p>Imagine that you want <strong>to weigh a water molecule</strong>. You cannot just place it on a weighing pan because it certainly would not work. You need a much more sophisticated device called <strong>a mass spectrometer</strong>.</p>
<p><strong>The first such instrument was constructed by J. J. Thomson in 1912</strong>. Since then, mass spectrometry has developed into a fascinating field with many practical applications.</p>
<p><a href="https://lcms.labrulez.com/library?categoryItems=12&amp;instrumentationItems=31&amp;publicationTypeItems=1-7-2-5-4&amp;search=newborn+screening"><strong>Newborn screeningg</strong></a>, <a href="https://lcms.labrulez.com/library?categoryItems=3&amp;instrumentationItems=31&amp;publicationTypeItems=1-7-2-5-4&amp;search=doping"><strong>doping tests of athletes</strong></a>, <a href="https://lcms.labrulez.com/library?categoryItems=1&amp;instrumentationItems=31&amp;publicationTypeItems=1-7-2-5-4&amp;search=contaminants"><strong>analysis of pollutants</strong></a>, <a href="https://lcms.labrulez.com/library?categoryItems=5&amp;instrumentationItems=31&amp;publicationTypeItems=1-7-2-5-4&amp;search=drug"><strong>testing of new drugs</strong></a> or <strong>space exploration</strong> are only a few <strong>examples of the application of mass spectrometry</strong>. Yet there are many more.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_Mass_Spectrometer_d6267dd11d/Czech-Museum-of-MS-Mass-Spectrometer.jpg" alt="Czech Museum of MS: Mass Spectrometer"/></p>
<h3><strong>MASS SPECTROMETER</strong></h3>
<p><strong>A mass spectrometer</strong> is a remarkable instrument that <strong>provides information about the mass and structure of molecules</strong>. In essence, it is a very accurate scale for electrically charged molecules. However, such a scale does not resemble the traditional ones known from kitchens and pharmacies. It is an ingenious device that <strong>uses electric and magnetic fields to manipulate, separate and detect charged molecules</strong>. Some instruments also make it possible to break charged molecules into pieces, which is useful for deducing the molecular structure.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_A_gridless_two_stage_reflectron_from_the_MALDI_TOF_system_Biflex_II_manufactured_by_Bruker_Daltonics_690d1900fb/Czech-Museum-of-MS-A-gridless-two-stage-reflectron-from-the-MALDI-TOF-system-Biflex-II-manufactured-by-Bruker-Daltonics.jpg" alt="Czech Museum of MS: A gridless two-stage reflectron from the MALDI-TOF system Biflex II manufactured by Bruker Daltonics"/></p>
<h3><strong>OUR MISSION</strong></h3>
<p>The museum aims <strong>to collect</strong> and <strong>display artifacts in mass spectrometry</strong>, especially those <strong>associated with our geographical region</strong>. Students professionals and the general public can look a the key components of spectrometers and understand <strong>how mass spectrometers work</strong>. The technical solutions and stories behind the exhibits can inspire young scientists as wall as experienced designers of scientific instruments.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_Mass_Spectrometry_history_in_Czech_Republic_fce8ca9112/Czech-Museum-of-MS-Mass-Spectrometry-history-in-Czech-Republic.jpg" alt="Czech Museum of MS: Mass Spectrometry history in Czech Republic"/></p>
<h3><strong>EXHIBITION</strong></h3>
<p>The exhibition shows instrument components tha are often <strong>hidden in inaccessible vacuum chambers of mass spectrometers</strong>. You can take a closer look at them, understand their function, and at the same time admire their technical perfection and beauty. Use your smartphone to learn more about the exhibit you are currently viewing. <strong>The posters on the walls will teach you about mass spectrometry and its history</strong>.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_A_grid_cell_of_LTQ_FT_Ultra_Thermo_Electron_Corporation_7e8ae7d076/Czech-Museum-of-MS-A-grid-cell-of-LTQ-FT-Ultra-(Thermo-Electron-Corporation).jpg" alt="Czech Museum of MS: A grid cell of LTQ FT Ultra (Thermo Electron Corporation)"/></p>
<h3><strong>DONATE AN EXHIBIT</strong></h3>
<p>The museum accepts <strong>donations</strong> to its collection, especially <strong>instruments</strong> or <strong>parts of them</strong> (even broken, damaged or worn), <strong>documents</strong>, and <strong>photographs related to mass spectrometry and its history</strong>. All donations are highly appreciated.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_EI_source_from_the_single_quadrupole_mass_spectrometer_TRIO_1000_manufactured_by_VG_Masslab_Altrincham_UK_9824bf2fd9/Czech-Museum-of-MS-EI-source-from-the-single-quadrupole-mass-spectrometer-TRIO-1000-manufactured-by-VG-Masslab-(Altrincham-UK).jpg" alt="Czech Museum of MS: EI source from the single quadrupole mass spectrometer TRIO 1000 manufactured by VG Masslab (Altrincham, UK)"/></p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Czech_Museum_of_MS_A_triple_stage_quadrupole_LC_MS_mass_spectrometer_TSQ_Vantage_manufactured_by_Thermo_Scientific_fbf31e162f/Czech-Museum-of-MS-A-triple-stage-quadrupole-LC-MS-mass-spectrometer-TSQ-Vantage-manufactured-by-Thermo-Scientific.jpg" alt="Czech Museum of MS: A triple stage quadrupole LC-MS mass spectrometer TSQ Vantage manufactured by Thermo Scientific"/></p>
<h3><strong>FIND US HERE</strong></h3>
<h5><a href="https://www.uochb.cz/en"><strong>Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences</strong></a></h5>
<ul>
<li>Building A, 2nd floor</li>
<li>Flemingovo náměstí 542/2</li>
<li>160 00 Praha 6</li>
<li>Czech Republic</li>
</ul>
<h3><strong>HOURS AND ADMISSION</strong></h3>
<p>The museum is <strong>open daily from 8 am to 6 pm.</strong> A guide is required to move around the building.</p>
<p><strong>Please call in advance</strong> to check the guide‘s availability.</p>
<ul>
<li><strong>Inquiries:</strong> Josef Cvačka</li>
<li>+420 731 447 868</li>
<li>josef.cvacka@uochb.cas.cz</li>
</ul>
<p><strong>The admission is free for all visitors.</strong></p>
<p><strong>The Czech Academy of Sciences has contributed financially to the promotion of the museum.</strong></p>


Czech Museum of Mass Spectrometry

<p><strong>In the week from February 13, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p>
<blockquote>
<h4><a href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in almost <strong>2 500 GC, LC nad MS webinars</strong></p>
</blockquote>
<h5><strong>1. Shimadzu Corporation: Introducing the latest version Lab-at-a-glance powered by LabSolutions BiX</strong></h5>
<ul>
<li>Tu, 14.2.2023, 07:00 (CET)</li>
</ul>
<p>LabSolutions BiX enables the monitoring of the Live Status of laboratory activities, the efficiency of laboratory users, instrument utilization, and other new features...</p>
<h5><strong>2. Technology Networks/Agilent Technologies: Advances in Multiomics Screening of Microbes in Biotechnology</strong></h5>
<ul>
<li>Tu, 14.2.2023, 16:00 (CET)</li>
</ul>
<p>In this webinar, the development and validation of the high-throughput, automated platform using model microbial organisms is described.</p>
<h5><strong>3. Separation Science/Agilent Technologies: Computerized System Validation: GAMP 5 2nd Edition, What You Need to Know</strong></h5>
<ul>
<li>We, 15.2.2023, 16:00 (CET)</li>
</ul>
<p>We shall take a look at the contents of the long awaited GAMP 5 Version 2 release to examine what has truly changed since the Version 1 release, with special focus on Pharma, BioPharma, and Biotech industries.</p>
<h5><strong>4. Thermo Fisher Scientific: Proteome Discoverer XlinkX Workshop</strong></h5>
<ul>
<li>We, 15.2.2023, 16:00 (CET)</li>
</ul>
<p>An online Proteome Discoverer crosslinking training workshop delivered, designed to get novice/intermediate users up to speed with the PD 3.0 (SP1) software package.</p>
<h5><strong>5. Phenomenex: Analytical BioSolutions for Therapeutic Oligonucleotides</strong></h5>
<ul>
<li>Th, 16.2.2023, 05:30 (CET)</li>
</ul>
<p>Reversed Phase-Ion Pair LC for Oligos - Challenges and Optimization...</p>
<h5><strong>6. Waters Corporation: PRINCIPLES OF SIZE EXCLUSION CHROMATOGRAPHY: OPTIMIZING PARTICLE SIZE, PORE SIZE, AND COLUMN DIMENSIONS</strong></h5>
<ul>
<li>Th, 16.2.2023, 16:30 (CET)</li>
</ul>
<p>This webinar series will cover the foundations of chromatography for the separation and analysis of peptides and proteins.</p>
<h5><strong>7. SelectScience/Agilent Technologies: Analysis of oligonucleotides by accurate mass LC/MS: Sequencing and impurity analysis to support development at Arrowhead Pharmaceuticals</strong></h5>
<ul>
<li>Th, 16.2.2023, 17:00 (CET)</li>
</ul>
<p>Learn from a practical demonstration about a case where LC/MS oligonucleotides analyses have been undertaken to confirm the molecular sequence, as well as to understand process impurities and degradants.</p>


Webinars LabRulezLCMS Week 7/2023

<p><strong>In the week from February 20, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p>
<blockquote>
<h4><a href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in almost <strong>2 500 GC, LC nad MS webinars</strong></p>
</blockquote>
<h5><strong>1. Waters Corporation: Empower Tips: Ask Me Anything About A Practical Approach to System Suitability</strong></h5>
<ul>
<li>Tu, 21.2.2023, 15:00 (CET)</li>
</ul>
<p>“No sample analysis is acceptable unless the requirements of System Suitability have been met.”</p>
<h5><strong>2. Waters Corporation: Creating Better Chromatographic Methods Using a Systematic Approach</strong></h5>
<ul>
<li>Tu, 21.2.2023, 17:00 (CET)</li>
</ul>
<p>We will discuss a systematic approach to LC method development, including an overview on how to ensure your LC system is performing optimally.</p>
<h5><strong>3. Technology Networks/PreOmics: Streamlining Protein Extraction for Proteomics and Beyond</strong></h5>
<ul>
<li>We, 22.2.2023, 16:00 (CET)</li>
</ul>
<p>You will discover ways to improve your protein extraction, such as by reducing workflow complexity, improving results from scarce samples, setting up robust assays and working with large sample cohorts.</p>
<h5><strong>4. Evosep Biosystems: SEPSIS</strong></h5>
<ul>
<li>Th, 23.2.2023, 16:00 (CET)</li>
</ul>
<p>In this webinar we will uncover how our users combine technology with the Evosep One to further research into sepsis and its biomarkers.</p>
<h5><strong>5. Technology Networks/SCIEX: High-Throughput Charge Variant Analysis of Therapeutic Proteins</strong></h5>
<ul>
<li>Th, 23.2.2023, 16:00 (CET)</li>
</ul>
<p>We will demonstrate that this task can be mastered using both capillary isoelectric focusing (cIEF) and capillary zone electrophoresis (CZE) analyses, as employed by the BioPhase 8800 system from SCIEX.</p>
<h5><strong>6. Agilent Technologies: Revisions to USP chapter 1724 - Dissolution Testing of Semisolids</strong></h5>
<ul>
<li>Th, 23.2.2023, 16:30 (CET)</li>
</ul>
<p>Join us to get an update on the latest changes and additions to USP chapter &lt;1724&gt;.</p>
<h5><strong>7. Waters Corporation: FOUNDATIONS OF REVERSE PHASE SEPARATIONS FOR PEPTIDES AND PROTEINS</strong></h5>
<ul>
<li>Th, 23.2.2023, 16:30 (CET)</li>
</ul>
<p>This webinar series will cover the foundations of chromatography for the separation and analysis of peptides and proteins.</p>
<h5><strong>8. Agilent Technologies: SEC Overview and Method Development for Biomolecules</strong></h5>
<ul>
<li>Th, 23.2.2023, 17:00 (CET)</li>
</ul>
<p>We will discuss the theory behind SEC, overview of mAbs, and characterization requirements.</p>


Webinars LabRulezLCMS Week 8/2023

<p><strong>In the week from February 27, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p>
<blockquote>
<h4><a href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in almost <strong>2 500 GC, LC nad MS webinars</strong></p>
</blockquote>
<h5><strong>0. Shimadzu Corporation: Revolutionary Single Quad LC-MS for Drug Development and Quality Control</strong></h5>
<ul>
<li>Tu, 28.2.2023, 20:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2429">Registration</a></li>
</ul>
<p>This webinar will demonstrate an LC-MS system that can perform both LC-MS analysis and LC-UV analysis.</p>
<h5><strong>1. Waters Corporation: Improving Chromatographic performance to next level with Waters Premier technology</strong></h5>
<ul>
<li>Th, 2.3.2023, 06:30 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2416">Registration</a></li>
</ul>
<p>The ACQUITY Premier system minimizes the analyte loss, improving recovery, and limits of detection.</p>
<h5><strong>2. Wiley Analytical Science/JMP Statistical Discovery: Making better use of Spectral and Chromatographic Data in product and process development</strong></h5>
<ul>
<li>Th, 2.3.2023, 11:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2388">Registration</a></li>
</ul>
<p>This webinar will present a simple and efficient way of extracting the signals from the noise for a deeper, better understanding of your processes and products.</p>
<h5><strong>3. Waters Corporation: Virtual European Workshops on Extractables &amp; Leachables for Pharma &amp; Biopharma</strong></h5>
<ul>
<li>Th, 2.3.2023, 14:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2414">Registration</a></li>
</ul>
<p>Register now for this virtual event and share knowledge and challenges with peers and E&amp;L experts.</p>
<h5><strong>4. The Analytical Scientist/ACD/Labs: How to Overcome the Challenges of Analytical Data Management</strong></h5>
<ul>
<li>Th, 2.3.2023, 16:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2390">Registration</a></li>
</ul>
<p>The challenges related to analytical data that cross organizations and industries; and lessons learned through their own experience.</p>
<h5><strong>5. Waters Corporation: ION-EXCHANGE SEPARATIONS AND BEST PRACTICES FOR SALTY SEPARATIONS</strong></h5>
<ul>
<li>Th, 2.3.2023, 16:30 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2356">Registration</a></li>
</ul>
<p>This webinar series will cover the foundations of chromatography for the separation and analysis of peptides and proteins.</p>
<h5><strong>6. Agilent Technologies: UV-Vis Instrumentation : From Routine to Advanced Applications Part I</strong></h5>
<ul>
<li>Th, 2.3.2023, 20:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2366">Registration</a></li>
</ul>
<p>The focus of Part I of this two part series will be on entry level and the mid-performance instrumentation and what is needed to make a variety of measurements.</p>


Webinars LabRulezLCMS Week 9/2023

<p><strong>In the week from March 6, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p>
<blockquote>
<h4><a href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4>
</blockquote>
<blockquote>
<p><strong>👉 Search and filter</strong> in almost <strong>2 500 GC, LC nad MS webinars</strong></p>
</blockquote>
<h5><strong>1. Agilent Technologies: Deep Generative Modeling in Computational Mass Spectrometry and Metabolomics</strong></h5>
<ul>
<li>Tu, 7.3.2023, 16:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2401">Registration</a></li>
</ul>
<p>We’ll discuss recent work in the development of deep generative modeling algorithms to enable chromatogram cleaning, de novo compound identification and metabolomics data synthesis and disentanglement.</p>
<h5><strong>2. C&amp;EN/Wyatt Technology: Real-Time Analysis of Product Attributes in Downstream Processing of Viral Vectors</strong></h5>
<ul>
<li>Tu, 7.3.2023, 17:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2402">Registration</a></li>
</ul>
<p>﻿We present the use of real-time multi-angle light scattering (RT-MALS) as a process analytical technology to optimize process development of viral vectors.</p>
<h5><strong>3. The Analytical Scientist/Thermo Fisher Scientific: Thermo Scientific™ µPAC™ Neo HPLC Columns – Pushing Proteomics Boundaries with micro-Pillar Chromatography</strong></h5>
<ul>
<li>We, 8.3.2023, 16:00</li>
<li><a href="https://lcms.labrulez.com/webinar/2411">Registration</a></li>
</ul>
<p>We will present the next generation Thermo Scientific µPAC Neo columns, specifically designed to further push the nanoLC separations to achieve deeper proteomic coverage with shorter runtime.</p>
<h5><strong>4. SelectScience/Thermo Fisher Scientific: The past, present, and future of food safety testing – a SelectScience Broadcast</strong></h5>
<ul>
<li>We, 8.3.2023, 17:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2439">Registration</a></li>
</ul>
<p>Through some enlightening interviews with food testing scientists and industry experts, we explores the changes in approach to food safety testing over time, across a wealth of innovative content.</p>
<h5><strong>5. SCIEX: PFAS summit: a scientific series (Day 1)</strong></h5>
<ul>
<li>We, 8.3.2023, 19:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2407">Registration</a></li>
</ul>
<p>Join the discussion as SCIEX customers and industry experts explore how forever chemicals have shaped our environmental research.</p>
<h5><strong>6. Waters Corporation: HILIC SEPARATIONS FOR GLYCANS AND GLYCOPEPTIDES</strong></h5>
<ul>
<li>Th, 9.3.2023, 16:30 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2357">Registration</a></li>
</ul>
<p>This webinar series will cover the foundations of chromatography for the separation and analysis of peptides and proteins.</p>
<h5><strong>7. C&amp;EN/Agilent Technologies: Automated Protein Sample Prep For Non-Automation Experts</strong></h5>
<ul>
<li>Th, 9.3.2023, 17:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2440">Registration</a></li>
</ul>
<p>The AssayMAP Bravo is a flexible yet easy-to-use automated micro chromatography-based protein sample preparation platform.</p>
<h5><strong>8. Waters Corporation: Empower Tips: Ask Me Anything About Column Performance and Data Management with Empower and eCord Technology</strong></h5>
<ul>
<li>Th, 9.3.2023, 17:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2435">Registration</a></li>
</ul>
<p>Key points: Importance of Data Integrity. Data Tracking and Trending of Column Performance. Intelligent eCord Chip Technology. Impact of System Suitability on Data Integrity.</p>
<h5><strong>9. Technology Networks/Bruker: Discovery of Lipid Biomarkers for Parkinson’s Disease Using TIMS Mass Spectrometry</strong></h5>
<ul>
<li>Th, 9.3.2023, 17:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2405">Registration</a></li>
</ul>
<p>Dr. Roberts will highlight how his work aims to identify disease-specific lipid isomers that can be used for the early detection and diagnosis of PD, using ion mobility mass spectrometry.</p>
<h5><strong>10. SelectScience/Andor Technology: The basic physics of spectroscopy: Light-matter interaction for fun and profit</strong></h5>
<ul>
<li>Th, 9.3.2023, 17:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2399">Registration</a></li>
</ul>
<p>This first session of a four-part ‘Fundamentals of Spectroscopy’ course, will examine core concepts essential to understanding common optical spectroscopy methods.</p>
<h5><strong>11. SCIEX: Accurate mass 101: targeted analysis and quantification</strong></h5>
<ul>
<li>Th, 9.3.2023, 19:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2437">Registration</a></li>
</ul>
<p>In this webinar series, SCIEX applications scientists will explain the benefits of using accurate mass, sample analysis, instrument operation and data processing in real-time.</p>
<h5><strong>12. SCIEX: PFAS summit: a scientific series (Day 2)</strong></h5>
<ul>
<li>Th, 9.3.2023, 19:00 (CET)</li>
<li><a href="https://lcms.labrulez.com/webinar/2408">Registration</a></li>
</ul>
<p>Join the discussion as SCIEX customers and industry experts explore how forever chemicals have shaped our environmental research.</p>


Webinars LabRulezLCMS Week 10/2023

Article

Product

Events

Webinars

Application

Academy

Video

Poster

Scientists

Plastics

Environment

Food

Water

Health

Presentation

Scientific article

Interview

Toxicology

Popularization

Science and research

Software

Covid-19

Career

Laboratories

Various

PFAS 

Zaměření

Type of News

Focus

is the international joint scientific meeting to share recent developments, exchange ideas, explore new directions and initiate a possible collaboration in the analytical spectrometry area.

ESAS

The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

Webinars LabRulezLCMS Week 10/2023

Webinars LabRulezLCMS Week 9/2023

Webinars LabRulezLCMS Week 8/2023

Webinars LabRulezLCMS Week 7/2023

Czech Museum of Mass Spectrometry

ESAS-CSSC 2022 (Day 5)

Webinars LabRulezLCMS Week 6-7/2023

Webinars LabRulezLCMS Week 5-6/2023

Tips & Tricks in Liquid Chromatography (HPLC Webinars 2022)

Webinars LabRulezLCMS Week 2-3/2023

Upcoming events

Bruker at SOFT-TIAFT 2026

Thermo Fisher Scientific at SOFT/TIAFT 2026

Thermo Fisher Scientific Environmental & Food Safety Workshop Series 2026

Webinars

Expanding the Evidence: New Data for More Reliable PFAS Analysis

How is capillary electrophoresis being used to analyze DNA and RNA

A novel monodisperse supermacroporous reversed-phase platform for comprehensive nucleic acid analysis across a broad size range