Propionic Acid Outperforms Formic and Acetic Acid in MS Sensitivity for High-Flow Reversed-Phase LC-MS Bottom-Up Proteomics
LCMSGCMSICPMSScientific article | Science and research

Propionic Acid Outperforms Formic and Acetic Acid in MS Sensitivity for High-Flow Reversed-Phase LC-MS Bottom-Up Proteomics

Propionic acid increases peptide identifications by 39% versus formic acid in LC-MS proteomics while maintaining chromatographic performance and compatibility.
Propionic Acid Outperforms Formic and Acetic Acid in MS Sensitivity for High-Flow Reversed-Phase LC-MS Bottom-Up Proteomics
News from LabRulezLCMS Library - Week 34, 2026
LCMSArticle | Poster

News from LabRulezLCMS Library - Week 34, 2026

This week we bring you posters by Agilent Technologies / ASMS, Thermo Fisher Scientific / ASMS and Shimadzu / ASMS and application note by Waters Corporation!
News from LabRulezLCMS Library - Week 34, 2026
4.5-Minute Oral Fluid LC MS Method to Detect 31 Drugs of Abuse Using Stellar MS
LCMSArticle | Application

4.5-Minute Oral Fluid LC MS Method to Detect 31 Drugs of Abuse Using Stellar MS

A fast 4.5-minute LC-MS workflow enables confirmation and quantitation of 31 drugs of abuse, including THC, in oral fluid using the Thermo Scientific Stellar mass spectrometer.
4.5-Minute Oral Fluid LC MS Method to Detect 31 Drugs of Abuse Using Stellar MS
Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability
LCMSArticle | Science and research

Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability

How can laboratories modernize legacy HPLC methods while remaining compliant? Learn how Opella leveraged UHPLC and evolving regulatory guidance to boost productivity.
Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability
How Bitter Acid Analysis Helps Brewers Better Control Beer Flavors
LCMSArticle | Academy

How Bitter Acid Analysis Helps Brewers Better Control Beer Flavors

Discover how online SPE combined with UHPLC accelerates hop bitter acid analysis, reduces solvent consumption, and delivers reliable data for better beer flavor control.
How Bitter Acid Analysis Helps Brewers Better Control Beer Flavors
Untargeted Metabolomics Identifies N-Lactoyl-Amino Acids as Dose-Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes
LCMSScientific article | Science and research

Untargeted Metabolomics Identifies N-Lactoyl-Amino Acids as Dose-Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

This study identifies N-lactoyl-amino acids as plasma biomarkers that accurately reflect metformin exposure and treatment adherence in T2D.
Untargeted Metabolomics Identifies N-Lactoyl-Amino Acids as Dose-Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes
Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS
LCMSArticle | Science and research

Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS

How can mAb manufacturing monitoring be simplified? Switchable 2D-LC-UV-MS workflows enable near real-time tracking of critical quality attributes and faster process decisions.
Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS
How to Cut HPLC Sample Preparation Time for Derivatizing Amino Acids
LCMSArticle | Science and research

How to Cut HPLC Sample Preparation Time for Derivatizing Amino Acids

Automated in-needle amino acid derivatization for HPLC-FLD reduces sample preparation time, improves reproducibility, and minimizes manual laboratory work.
How to Cut HPLC Sample Preparation Time for Derivatizing Amino Acids
Behind the Bench: Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse Using LC-MS
LCMSArticle | Application

Behind the Bench: Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse Using LC-MS

Learn how to improve THC detection in LC-MS toxicology workflows. Smart extraction strategies, optimized columns, and buffers can boost signal, stability, and recovery across drug panels.
Behind the Bench: Tips to Simultaneously Analyze THC, Its Metabolites, and Other Drugs of Abuse Using LC-MS
Ask the Experts: Practical Answers to Today’s Biggest MOSH/MOAH Analysis Questions
GCMSLCMSArticle | Science and research

Ask the Experts: Practical Answers to Today’s Biggest MOSH/MOAH Analysis Questions

Expert insights from Thermo Fisher and SampleQ on MOSH/MOAH analysis using LC-GC-FID and GC×GC-FID/MS. Practical guidance on sample preparation, ISO 20122, internal standards, and data workflows.
Ask the Experts: Practical Answers to Today’s Biggest MOSH/MOAH Analysis Questions