In the week from November 30, 2020, the following webinars await you in the field of GC and GCMS. More <a href="https://gcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:
Now, you have possibility also search and filter in almost 600 GC and LC webinars.
1. Agilent Technologies: Dual Column Dual FID Analysis of USP&lt;467&gt; 
2. Thermo Fisher Scientific: Gain new impactful insights for your analysis with Thermo Scientific GC-Orbitrap MS and Compound Discoverer 3.2 software
3. Thermo Fisher Scientific: Advanced GC technology to maintain productivity in a pandemic
4. Restek Corporation: Analysis of Amines/Alkanolamines via GC
5. Separation Science/Agilent Technologies: After the Shut Down: Back to Business as Unusual
6. Phenomenex: Troubleshooting for Gas Chromatography
7. Phenomenex: How to Simplify and Optimise Your Traditional Reversed-Phase SPE Process
8. C&amp;EN/PerkinElmer: Improving Hand Sanitizer Analysis with quick and confident results
9. Thermo Fisher Scientific: Expanding the biomolecular structural analysis capabilities in XlinkX 2.5 for Thermo Scientific Proteome Discoverer 2.5 software
10. C&amp;EN/Syft Technologies: Halitosis Diagnosis and Control Using SIFT-MS
11. Thermo Fisher Scientific: FreeStyle: RAW Data Browsing and Analytics Software, and Almanac Instrument Monitoring and Management software
12. GERSTEL: Eliminate Doubt, Discover the Unknown: Aroma and Flavor Analysis in Food and Beverage Samples
In the week from December 7, 2020, another <a href="https://gcms.labrulez.com/webinars">7 webinars</a> are waiting for you in the field of GC and GCMS.

GC and GCMS webinars - Week 49

In the week from November 30, 2020, the following webinars await you in the field of LC and LCMS. More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:
Now, you have possibility also search and filter in almost 600 GC and LC webinars.
1. Restek Corporation: HPLC Troubleshooting - Part 2
2. PerkinElmer: Advanced Quality Assured Strategies for Multi Mycotoxin Analysis in Food
3. Wiley/MERCK: Mass Spectrometric Analysis of Vitamin D Metabolites
4. Wiley/MERCK: Reshaping the Lipid Science Landscape
5. VWR: Back To Basics: Fundamental Concepts of HPLC &amp; UHPLC
6. Separation Science/Agilent Technologies: After the Shut Down: Back to Business as Unusual
7. Phenomenex: How to Simplify and Optimise Your Traditional Reversed-Phase SPE Process
8. SelectScience/Waters Corporation: Compliance-ready intact mass analysis of modified oligonucleotides and impurities using the BioAccord LC-MS System
9. Thermo Fisher Scientific: Tips and tricks to select HPLC columns
10. PerkinElmer: PerkinElmer Medical LC-MS/MS Seminar at UToledo
11. Thermo Fisher Scientific: Expanding the biomolecular structural analysis capabilities in XlinkX 2.5 for Thermo Scientific Proteome Discoverer 2.5 software
12. Thermo Fisher Scientific: How to rely on productivity of your HPLC system during a pandemic
13. LCGC/Agilent Technologies: Poly- and Perfluoroalkyl Substances in Water: Challenges and Mitigating Strategies in Detection and Treatment
14. Shimadzu Scientific Instruments: Shimadzu&#39;s LC Method Development (RP) Series - Session 2: Optimising your Method
15. LCGC/Agilent Technologies: Identification, Mapping and Relative Quantitation of SARS-CoV-2 Spike Glycopeptides by Mass-Retention Time Fingerprinting
16. Thermo Fisher Scientific: FreeStyle: RAW Data Browsing and Analytics Software, and Almanac Instrument Monitoring and Management software
In the week from December 7, 2020, another <a href="https://lcms.labrulez.com/webinars">14 webinars</a> are waiting for you in the field of LC and LCMS.

LC and LCMS webinars - Week 49

Take a look at the latest trends in drug production analysis using gas chromatographs (GC), headspace autosamplers (HS), GC/MS, GC/QQQ, or the combination of gas chromatography with high resolution mass spectrometers (HRMS).
The latest technologies push the boundaries of detection limits in all application areas - from the analysis of residual solvents, through today&#39;s critical analyzes of nitrosamines to the analysis of extractable and leachable substances from packaging materials.
Thanks to the possibilities of our unique database with advanced search, you are able to search and filter in a second according to the exact configuration of the system, manufacturer or industries.
All documents directly available in <a href="https://gcms.labrulez.com/library?categoryItems=5&amp;publicationTypeItems=1-2-7-5-4&amp;date=2019-2020">LabRulezGCMS database</a>.
<h3>GC/HRMS (2)</h3>
<ul>
<li>Analytical solutions for challenges in headspace GC-MS analysis of volatile extractable and leachable compounds |2019| Thermo Fischer Scientific
</li>
<li>Extractables &amp; LeachablesAnalysis of Pharmaceutical Nasal Spray Samples using the Hi-Resolution Accurate Mass GC/QTOF |2019| Agilent Technologies
</li>
</ul>
<h3>GC/QQQ (7)</h3>
<ul>
<li>Combined Direct Injection N-Nitrosodimethylamine (NDMA),N-Nitrosodiethylamine (NDEA), N-Nitrosoethylisopropylamine (NEIPA), N-Nitrosodiisopropylamine (NDIPA), and N-Nitrosodibutylamine (NDBA)Impurity Assay by GC-MS/MS | 2019 | Ostatní
</li>
<li>Analysis of Five Nitrosamine Impurities in Drug Products and Drug Substances Using Agilent GC/MS/MS Instrumentation | 2020 | Agilent Technologies
</li>
<li>Analysis of Pharmaceuticals’ Impurity - Regulations and Analysis for Carcinogenic Substances | 2020 | Shimadzu
</li>
<li>Nitrosamine Impurities Application Guide - Confidently Detect and Quantify Mutagenic Impurities in APIs and Drug Products | 2020 | Agilent Technologies
</li>
<li>Quantification of Nitrosamine Impurities in Metformin Using Agilent GC/MS/MS Instrumentation | 2020 | Agilent Technologies
</li>
<li>Overcoming the challenges of nitrosamine impurities in drugs | 2020 | Thermo Fischer Scientific
</li>
<li>Determination of 33 pesticide residues in Ginseng using gas chromatography-triple quadrupole mass spektrometry | 2020 | Shimadzu
</li>
</ul>
<h3>GC/SQ (12)</h3>
<ul>
<li>Determination of genotoxic nitrosamines in Valsartan with gas chromatography and mass spektrometry | 2019 | Thermo Fischer Scientific
</li>
<li>Analysis of N-Nitrosodimethylamine and N-Nitrosodiethylamine Using the Agilent 7697A Headspace Sampler, 8890/5977 GC/MSD Systém | 2019 | Agilent Technologies
</li>
<li>Analysis of USP &lt;467&gt; Residual Solvents of Class 1, Class 2, and Class 3 using the Agilent 8890 GC/ FID /5977B MSD Systém | 2019 | Agilent Technologies
</li>
<li>Selective and Sensitive Analysis of 20 Category I and II Residual Solvents for Cannabis Application using Headspace-GCMS | 2020 | Shimadzu
</li>
<li>Analysis of Terpene and Terpenoid Content in Cannabis Sativa Using Headspace with GC/MSD | 2020 | Agilent Technologies
</li>
<li>Analysis of NDMA and NDEA in Sartan Drugs and Drug Products by GC-MS on a Zebron™ ZB-624PLUS™ | 2019 | Phenomenex
</li>
<li>Agilent ASMS 2020 Posters Book | 2020 | Agilent Technologies
</li>
<li>Analysis of Pharmaceuticals’ Impurity - Regulations and Analysis for Carcinogenic Substances | 2020 | Shimadzu
</li>
<li>Nitrosamine Impurities Application Guide - Confidently Detect and Quantify Mutagenic Impurities in APIs and Drug Products | 2020 | Agilent Technologies
</li>
<li>Overcoming the challenges of nitrosamine impurities in drugs | 2020 | Thermo Fischer Scientific
</li>
<li>Thermal Desorption – GCMS Method for Screening Analysis of Extractables in Drug Packaging Materials | 2020 | Shimadzu
</li>
</ul>
<h3>GC (15)</h3>
<ul>
<li>Analysis of Residual Solvents in Pharmaceuticals An Analysis Method for Class 2 Solvents (Water- Soluble Samples) Unsuited to Headspace GC Methods | 2019 | Shimadzu
</li>
<li>Analytical solutions for challenges in headspace GC-MS analysis of volatile extractable and leachable compounds | 2019 | Thermo Fischer Scientific
</li>
<li>Analysis of USP Method &lt;467&gt; Residual Solvents on the Agilent 8890 GC System | 2019 | Agilent Technologies
</li>
<li>Analysis of USP &lt;467&gt; Residual Solvents of Class 1, Class 2, and Class 3 using the Agilent 8890 GC/ FID /5977B MSD System | 2019 | Agilent Technologies
</li>
<li>Enhanced Productivity for Residual Solvent Analysis in Pharmaceutical Products According to USP 467 by Using a New Valve and Loop Static Headspace Sampler | 2019 | Thermo Fischer Scientific
</li>
<li>Investigation of Key Parameters for a Smooth Method Transfer to a New Optimized Valve and Loop Headspace Autosampler | 2019 | Thermo Fischer Scientific
</li>
<li>Investigation of key parameters for a smooth method transfer to the new Thermo Scientific TriPlus 500 Headspace Autosampler | 2019 | Thermo Fischer Scientific
</li>
<li>System Suitability Test of Low-Substituted Hydroxypropyl Cellulose for USP42-NF37 | 2020 | Shimadzu
</li>
<li>Analysis of Residual Solvents in Pharmaceuticals by Nexis™ GC-2030 + HS-20 (JP17 Supplement II, USP 467) | 2020 | Shimadzu
</li>
<li>Analysis of Residual Solvents in Pharmaceuticals by Water-Soluble Samples Using N2 Carrier (JP17 Supplement II, USP 467) | 2020 | Shimadzu
</li>
<li>Analysis of Residual Solvents in Pharmaceuticals by Water-Insoluble Samples Using N2 Carrier (JP17 Supplement II, USP 467) | 2020 | Shimadzu
</li>
<li>Analysis of Volatile Impurities in Anhydrous Ethanol and Ethanol for Disinfection in Accordance with the Purity Test set by the Pharmacopoeias (JP, USP, EP) | 2020 | Shimadzu
</li>
<li>Alcohol Determination of Sanitizer Gel in accordance with USP&lt;611&gt; | 2020 | Shimadzu
</li>
<li>Analysis of Residual Solvents in Pharmaceutical Products by Headspace-GC-FID with Nitrogen Carrier Gas Following USP&lt;467&gt; - Procedure B | 2020 | Shimadzu
</li>
<li>Packed Column Analysis of Alcohol Number Determination Conforming to Japanese Pharmacopoeia Using Nexis™ GC-2030 (FID) | 2020 | Shimadzu
</li>
</ul>

Pharmaceutical analysis - An overview of the latest possibilities of using GC a GCMS systems 2019-2020

Gas chromatography is a very important analytical technique used for the determination of flavors which content is significant not only for monitoring of quality of final product but also in testing of new technological procedures. In brewing analytics the most frequently used gas chromatographic detectors are flame ionization detector (FID), electron capture detector (ECD), and flame photometric detector (FPD). This work is focused on principles of these detectors, their advantages and limitations during using in brewing analytics. Gas chromatography is a very important analytical technique used for the determination of flavors which content is significant not only for monitoring of quality of final product but also in testing of new technological procedures. In brewing analytics the most frequently used gas chromatographic detectors are flame ionization detector (FID), electron capture detector (ECD), and flame photometric detector (FPD). This work is focused on principles of these detectors, their advantages and limitations during using in brewing analytics.
<h3>1 INTRODUCTION</h3>
Official methods of brewery institutions as European Brewery Convention (EBC), Mitteleuropäische Brautechnische Analysenkommission (MEBAK), The Institute of Brewing (IOB) or The American Society of Brewing Chemists (ASBC) include gas chromatographic procedures used for the determination of beer flavors. Beer flavors or some contaminants can be determined by this separation procedure as in intermediate products as in final beer. The review of these compounds including used detector is shown in Tab. 1.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/556a0c31a9b345bab673116d42d5e72b/obrazek.png" alt="Tab. 1 List of compounds determined by gas chromatography in brewing analytics according to detector type"/>
Flame ionization detector (FID) is the most useful gas chromatographic (GC) detector available and by far that most commonly used in GC analyses. In comparison with FID electron capture detector (ECD) and flame photometric detector (FPD) are characterized by higher sensitivity and higher selectivity for selected analytes and so these detectors are also often used.
A detector that can selectively respond to compounds of real inte - rest in a mixture and ignore those compounds of little interest is potentially able to improve efficiency by two ways. Firstly the amount of sample clean-up required to remove unwanted and interfering compounds from the sample, may be reduced thereby simplifying preanalysis sample handling. Secondly, analysis time on the chromatograph may be shortened since it may no longer be necessary to achieve complete separation of all components in the mixture. 
It is for these two reasons that the selective detectors are the most frequently used ones. However, while selective detectors can provide undoubted benefits, their use can cause other problems, particularly when their mode of operation is not fully understood or their capabilities not fully utilized.
In this paper the principles of above mentioned detectors are described together with their utilization in brewing analytics.
<h3>2 THE FLAME IONIZATION DETECTOR (FID)</h3>
The flame ionization detector FID has a very wide dynamic range, a high sensitivity and (with the exception of a few low molecular weight compounds) will detect all substances that contain carbon. The first FID was described about the same time by Harley and Pretorious (25), and McWilliams and Dewer (26). Hydrogen is mixed with the column eluent and burned at a small jet. Surrounding the flame is a cylindrical electrode and a relatively high voltage is applied between the jet and the electrode to collect the ions that are formed in the flame. The resulting current is amplified by a high impedance amplifier and the output fed to a data acquisition system or a potentiometric recorder. The detector usually requires three separate gas supplies together with their precision flow regulators. The gases normally used are hydrogen for combustion, helium or nitrogen as the carrier gas and oxygen or air as the combustion agent. The detector is normally thermostatted in a separate oven; this is not because the response of the FID is particularly temperature sensitive but to ensure that no solutes condense in the connecting tubes.
<h5>2.1 The response mechanism of the FID</h5>
The ionizing mechanism of the FID was carefully examined by Ongkiehong (27) and Desty (28) in 1960 and it would appear no such detailed evaluation of the detector has been carried out since. The ionization mechanism in the FID flame was originally thought to be similar to the ionization process in a hydrocarbon flame which was studied intensively by Calcote and King (29) and Schuler and Weber (30) in the mid–1950s. The present generally accepted explanation is that ions are not formed by thermal ionization but by thermal emission from microscopic carbon particles that are formed during the combustion process. Consequently the dominating factor in the ionization of organic material is not their ionization potential but the work function of the carbon that is transiently formed during their combustion.
The flame plasma contains both positive ions and electrons which are collected on either the jet or the plate depending on the polarity of the applied voltage. Initially, the current increases with applied voltage, the magnitude of which depends on the electrode spacing. The current continues to increase with the applied voltage and eventually reaches a plateau at which the current remains sensibly constant. The voltage at which this plateau is reached also depends on the electrode distances. Once electron/ion pair production is initiated the recombination starts to take place. The longer the ions take to reach the electrode the more recombination takes place. Thus, the greater the distance between the electrodes and/or the lower the voltage, the greater the recombination. This is substantiated by the curves obtained by Ongkiehong: the plateau is reached at a lower voltage when the electrodes are closer together. It is seen that the plateau level is the same for both electrode conditions and it is assumed that on the plateau, all ions and electrons being produced in the flame are collected. In practice the applied voltage would be adjusted to suit the electrode distance to ensure that the detector operates under conditions where all electrons and ions are collected.
<h5>2.2 The operation of the FID</h5>
The FID is probably the simplest, easiest and most reliable detector to operate. Generally the appropriate flow rates for the different gases are given in the detector manual. Hydrogen flows usually range between 20 and 30 ml per min, air flows are about 6 times the hydrogen flow e.g. 120 to 200 ml per min. The capillary column flow rate may be less than 1 ml per min for very small diameter columns. The mobile phase can be any inert gas–helium, nitrogen, argon etc. To some extent the detector is self-cleaning and rarely becomes fouled. However, this depends a little on the substances being analyzed. In case of brewing and malting analyses the possibility of contamination of FID is minimized.
<h3>3 THE ELECTRON CAPTURE DETECTOR (ECD)</h3>
The electron capture detector ECD utilizes the fundamental observation that the conductivity of gases in an ionization chamber can be drastically altered by the presence or absence of contamination in the gas. Thus the ECD consists of an ionization chamber containing a radioactive source, usually nickel – 63 (characterized by long lifetime and temperature stability up to 450 °C), with a stream of inert gas usually nitrogen, flowing through it. The β-ray emanation from the source causes ionization of the inert gas with a consequent liberation of free electrons. This may be written simple as (1):
(1) N₂ + β-ray ↔ N₂⁺ + e⁻
The ionization chamber is connected to a low voltage potential and a current measuring device. The applied potential causes the liberated electrons to migrate to the anode where collection occurs and a current flow is established. By careful adjustment of the applied potential, an equilibrium can be established whereby the electrons produce in the ionizing process are all collected at the anode. This can be achieved because the mobility of the free electrons is greater than that of the positive ions and hence free electrons migrate to the anode before recombination can occur.
Therefore, in the steady state a constant current known as the standing current, can be measured flowing in the chamber. The area between the source and the anode where electron liberation is occurring is known as the plasma region. If an electrophilic compound is now introduced to the chamber, a reaction will occur between this compound and the free electrons as follows (2,3):
(2) e⁻ + AB ↔ AB⁻ non-dissociative (3) e⁻ + AB ↔ A⁰ + B⁻ dissociative
As a result of these reactions, the fast moving electrons are replaced by slow moving negative ions. These slow negative ions take longer to migrate to anode and so have a higher probability of recombination with positive ions before reaching the anode than the electrons. Thus the nett results of introducing an electrophilic compound will be a decrease in the amount of current flow measured in the chamber.
The free electrons may in fact be moving so fast to the anode after their production that these necessary collisions and reactions do not have time to occur before the electron reaches the anode. So it is necessary to slow down the free electrons. The make-up gas, usually nitrogen, is used for this. The mobility of electrons is reduced by nonelastic collisions with the electrons (31).
<h5>3.1 Effect of temperature</h5>
The reaction between the sample molecule and free electros can be of two types – dissociative and non-dissociative (see equation 2,3). The dissociative reaction requires considerable energy for the dissociation of the sample molecule to occur during the reaction. An increase of detector temperature will effectively increase the energy of both the sample molecule and the electron and so will increase the ease of the dissociative reaction. The non-dissociative reaction, however, results in an increase of the energy of the sample molecule which has to be dispersed before a stable complex can be formed. An increase of detector temperature in this case would result in less chance of a non-dissociative reaction occurring. 
Very simply then, the detector temperature can influence the sensitivity of the detector. For non-dissociative reactions, as low a detector temperature as possible, as is compatible with column temperature, should be used. For dissociative reactions, the higher the detector temperature the greater its sensitivity.
The type of reaction involved can be easily identified by injection of the sample at different detector temperatures. A decision can then be taken on the two responses as to whether the detector should be operated at a low or high temperature.
The determination of vicinal diketones (diacetyl and 2,3-pentanedione) and chlorinated aliphatic hydrocarbons in beer are examples of these two different principles. Fig. 1 shows the effect of increasing temperature on the response of those two groups of compounds. During vicinal diketones analyse non-dissociative reactions take part and the lowest ECD temperature is recommended. While in aliphatic chlorinated hydrocarbons determination dissociative reactions are of use. The results were obtained in our laboratory using Thermo Scientific Trace Ultra gas chromatograph.
<h5>3.2 Practical notes</h5>
For high degree of sensitivity and selectivity of electron capture detector the following points should be noted and adhered to:
Always keep the detector temperature well above that of the column to prevent condensation of sample and/or stationary phase in the detector. Use small-sized samples of not more than 1 nanogram of strongly electron capturing material. The detector is so sensitive to these compounds that they will overload and saturate the detector even for several hours.
Always maintain a high total flow through the detector (usually not less than 40–50 ml/min) to ensure that all dead volumes are swept out.
Never use columns at or above the maximum temperature that is recommended for the stationary phase in the column. Because of the great sensitivity of the electron capture detector, small amounts of stationary phase bleed will cause a loss of standing current with a consequent loss of sensitivity. Moreover, any bleed from the column is not combusted, as on the flame ionization detector, and will tent to condense in the ECD.
A loss of standing current which is noticed after each injection indicates that contamination of the detector by compounds in the sample is occurring. If this is experienced, it is advisable to clean the detector regularly overnight by purging at an elevated temperature until the original standing currents are recovered. 
Many types of solvent can be electron capturing (e.g. acetone, alcohol, ether and any chlorinated solvent). Even small injections of these solvents will eventually saturate the ECD.
Since carrier gas and make-up gas is continually passing through the detector, any contamination in these gases will quickly build-up in the detector thereby reducing the detector standing current. It is necessary, therefore, to ensure that gases used with the ECD are quite clean. This can be achieved by using gases in ECD quality or by cleaning gases through special filters.
<h3>4 THE FLAME PHOTOMETRIC DETECTOR (FPD)</h3>
The flame photometric detector (FPD) was described by Grant (32) in 1958. The fundamental principle of the flame photometric detector is based on specific emission of light during combustion processes. This detector is used for the detection of sulphur and phosphorus compounds.
The end of the capillary column is led into the flame jet where the column eluent mixes with the hydrogen flow and is burnt. The jet and the actual flame is shielded to prevent light from the flame itself falling directly on to the photo-multiplier. The base of the jet is heated to prevent vapor condensation. The light emitted above the flame, first passes through two heat filters and then through the wavelength selector filter and finally on to the photo-multiplier. Under the correct conditions, the combustion of phosphorus and sulphur compounds produces two species, HPO and S₂, which give off characteristic emissions at 526 and 394 nm wavelengths respectively. The response of the detector to sulfur is fairly insensitive to changes in hydrogen flow rate. However, the response to phosphorus compounds shows a maximum at a particular hydrogen flow rate, the magnitude of which varies with the air flow.
<h5>4.1 Non linear response</h5>
The largest number of user problems with the flame photometric detector is caused by the square law dependence of the detector when used in the sulphur mode. This effect shows itself during changes in retention time in the detection of very small amounts of analytes. In linear detector a change in retention time will cause a decrease in peak height and hence a decrease in the limit of detection. With a square law detector this effect is exaggerated and in trace determination the peak could disappear into the general noise level.
From this reason it is important to pay attention to factors influenced detector’s noise. Excessive flame noise can be usually caused by not running the flame at the recommended gas flow rates, by using contaminated gas or by column bleeding caused by operating the column at a too high temperature. Another source of excess noise could be the photomultiplier tube because it is susceptible to water condensation. This problem could appear when temperature varies over a large range or when the flame is not alight. It is to be expected, therefore, that on startup from cold, the noise may be rather more than normal. In a short time, however, the condensation would clear and the noise decrease (31).
<h3>5 CONCLUSIONS</h3>
Developments of gas chromatography are now relatively slow. In the detector sector different types of special mass detector are extended because the prices of these units depreciate and so these equipments are easily available. Nevertheless the detectors FID, ECD and FPD are always wide-spread and for routine brewing and malting analyses are fully sufficient.

Main gas chromatographic detectors used in brewing analytics

N-nitrosamines in 21th Century

In the week from December 7, 2020, the following webinars await you in the field of GC and GCMS. More <a href="https://gcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:
Search and filter in more than 600 GC and LC webinars.
1. Restek Corporation: Tips and Tricks for Handling Reference Standards
2. Separation Science/Merck: Overview of Air Sampling Techniques for Environmental Contaminants
3. LCGC/Agilent Technologies: Regulatory Requirements and Analytical Strategies to Analyze Extractables and Leachables
4. Separation Science/Agilent Technologies: Advancements and Key Parameters for EPA 8260 and EPA 524.2 using GC/MS with Purge and Trap
5. LCGC/JEOL: Solving Problems with GC, Direct Sample Introduction, and High-Resolution Mass Spectrometry
6. Thermo Fisher Scientific: Increased confidence in peptide identification and quantification using Thermo Scientific Proteome Discoverer 2.5 software and INFERYS Rescoring
7. PerkinElmer: Eliminate Extractions and Simplify Sample Prep with SPME
8. LCGC/Agilent Technologies: Successfully Restarting Lab Operations: GC &amp; GC/MS
In the week from December 14, 2020, another <a href="https://gcms.labrulez.com/webinars">7 webinars</a> are waiting for you in the field of GC and GCMS.

GC and GCMS webinars - Week 50

In the week from December 7, 2020, the following webinars await you in the field of LC and LCMS. More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:
Search and filter in more than 600 GC and LC webinars.
1. Agilent Technologies: Higher Capacity, Lower Complexity – InfinityLab LC Fraction Collector Clusters
2. LCGC/Agilent Technologies: Regulatory Requirements and Analytical Strategies to Analyze Extractables and Leachables
3. SelectScience/Waters Corporation: Non-specific adsorption: Common causes, how it affects chromatographic results, and how to prevent it
4. Technology Networks/Thermo Fisher Scientific: Native Mass Spectrometry and COVID-19: Uncovering Drug Binding and Oligomerization 
5. Bruker Daltonics: Classification of Invasive Melanoma by Imaging Mass Spectrometry
6. Thermo Fisher Scientific: Increased confidence in peptide identification and quantification using Thermo Scientific Proteome Discoverer 2.5 software and INFERYS Rescoring
7. Agilent Technologies: Quantification of Organophosphorus Nerve Agent Metabolites (OPNA) on the 6495C
8. Agilent Technologies: Next Generation Bio LC Solutions: Workflow solutions with the new 1290 Infinity II Bio LC System with High-Speed Pump
9. Separation Science/Agilent Technologies: Super Charge your Method Development with a Quick, Easy Universally Compatible LC and LC/MS Method
10. LCGC/Agilent Technologies: LC/MS/MS Workflow to Determine over 500 Pesticides Residues in Compliance with SANTE 12682/2019 Guidelines
11. Technology Networks/SCIEX: Analysis of Process Related Impurities in Cell &amp; Gene Therapy Products by SWATH LC-MS
12. SelectScience/Phenomenex: Sample Preparation Strategies for Oligonucleotides Bioanalytical Workflows
13. Agilent Technologies: WHAT Do I Need for Successful Method Development?
14. Agilent Technologies: Understanding the Language of Liquid Chromatographic Results
15. LCGC/Agilent Technologies: The benefits of dedicated HPLC and chromatography column for analysis of Biomolecules
In the week from December 14, 2020, another <a href="https://lcms.labrulez.com/webinars">11 webinars</a> are waiting for you in the field of LC and LCMS.

LC and LCMS webinars - Week 50

In the week from December 14, 2020, the following webinars await you in the field of GC and GCMS. More <a href="https://gcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:
Search and filter in more than 600 GC and LC webinars.
1. Agilent Technologies: Laboratory Workflow Solutions: What to expect when you’re away from the lab?
2. Agilent Technologies: OpenLab CDS Introductory Demonstration
3. Restek Corporation: Trace sulfur analysis in hydrocarbon streams
4. Technology Networks/Agilent Technologies: Debunked: The Truths Behind Pesticide Testing
5. Agilent Technologies: New GC Column Technology for Old Problems in Fatty Acid Analysis
6. Agilent Technologies: Seminar 1 – OpenLab CDS - The Control Panel and Data Acquisition
7. Separation Science/Markes International: Passive Sampling and Its Pivotal Role in ʹGreenerʹ Sampling of VOCs

GC and GCMS webinars - Week 51

In the week from December 14, 2020, the following webinars await you in the field of LC and LCMS. More <a href="https://lcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:
Search and filter in more than 600 GC and LC webinars.
1. SelectScience/CAMAG: A new approach to fully automated QC with high-performance thin-layer chromatography
2. Agilent Technologies: Laboratory Workflow Solutions: What to expect when you’re away from the lab? 
3. Agilent Technologies: OpenLab CDS Introductory Demonstration
4. Technology Networks/Agilent Technologies: Debunked: The Truths Behind Pesticide Testing
5. Agilent Technologies: Seminar 1 – OpenLab CDS - The Control Panel and Data Acquisition
6. Phenomenex: Benefits of Phenyl Stationary Phase Chemistries in HPLC
7. SelectScience/Waters Corporation: Taming the Viral Beast: Applying LC and LC-MS Technologies to the Analysis of rAAV Viral Vectors
8. C&amp;EN/Thermo Fisher Scientific: Comprehensive solutions to Nitrosamine impurity analysis: an industry case study
9. Bruker Daltonics: Moving Away From Immunoassays: Adapting LC-MS for Routine Urine Toxicology Screens
10. Agilent Technologies: Dual Laser Scattering Use in the Characterization of Proteins including mAbs
11. Shimadzu Scientific Instruments: Shimadzu&#39;s LC Method Development (RP) Series - Session 3: Approach to Rectifying Changes in Data
12. Agilent Technologies: Advancements in Liquid Chromatography Method Development and Method Optimization

LC and LCMS webinars - Week 51

In the week from December 21 until the end of the year 2020, the following webinars await you in the field of GC and GCMS. More <a href="https://gcms.labrulez.com/webinars">details and registration can be found in the WEBINARS section.</a>:
Search and filter in more than 600 GC and LC webinars.
1. Agilent Technologies: Seminar 2 – OpenLab CDS – Data Analysis
2. Agilent Technologies: Seminar 3 – OpenLab CDS – Custom Calculator and Reporting

GC and GCMS webinars - Week 52

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Vědecký recenzovaný online časopis Kvasný průmysl (eISSN 2570-8619), vychází jako samostatné periodikum v angličtině. Od ročníku 2015 je obsah indexovaný databází Web of Science (edice ESCI), dále je indexován v databázích CAS, CAB Abstracts, DOAJ.
Časopis je publikovaný v režimu otevřeného přístupu Platinum Open Access s licencí Creative Commons. 

The journal Kvasny Prumysl

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