Wiley releases the 2026 Wiley Registry/NIST Mass Spectral Library, expanding its GC-MS reference collection to more than 1.2 million validated EI mass spectra.

Learn how NIST MS Interpreter connects accurate-mass MS/MS fragments with molecular structure, enabling substructure assignment, ppm evaluation, candidate modification, and improved unknown identification.

Learn how extracted ion chromatograms support LC–MS/MS identification, quantitation, isotope validation, and troubleshooting in the NIST XIC Analyzer workflow.

Learn how to recognize and search in-source fragmentation spectra in NIST26 using chromatogram results, Score (Unfiltered), and MS/MS Library Search for compound identification.

A practical guide to processing LC-MS/MS data in the NIST26 Chromatogram Window, from parameter setup and library searching to identification review and result export.

Discover the new NIST26 LC-MS/MS workflow with integrated chromatogram analysis, expanded MS/MS libraries, hybrid searching, and advanced tools for confident unknown compound identification.

Learn how NIST MS Search stores library search history, what HLM files are used for, and how to automatically remove temporary files to keep your workspace clean and organized.

Discover what the NIST Identification Folder contains during low-resolution EI GC-MS processing. Learn how TIC, ELU, FIN, TSV, RUN, and LOG files support deconvolution and library searching.

Transfer HPLC methods to modern column dimensions with ease. Discover how the free KNAUER HPLC Method Converter simplifies method adaptation, supports USP compliance, and reduces solvent use.

Wiley has released the NIST/EPA/NIH EI Mass Spectral Library 2026 and NIST MS/MS Spectral Library 2026, featuring expanded spectral collections, updated search software, and separate EI and MS/MS products.