Aromatase Inhibitor Therapy Is Associated with Distinct Plasma Lipidomic Profiles in Postmenopausal Breast Cancer Patients
LCMSScientific article | Science and research

Aromatase Inhibitor Therapy Is Associated with Distinct Plasma Lipidomic Profiles in Postmenopausal Breast Cancer Patients

Mass spectrometry-based lipidomics identifies distinct plasma lipid changes linked to long-term aromatase inhibitor therapy in postmenopausal breast cancer patients.
Aromatase Inhibitor Therapy Is Associated with Distinct Plasma Lipidomic Profiles in Postmenopausal Breast Cancer Patients
ABCA7 deficiency exacerbates glutamate excitotoxicity in Alzheimer’s disease mice – A new pharmacological target for Glu-related neurotoxicity
LCMSScientific article | Science and research

ABCA7 deficiency exacerbates glutamate excitotoxicity in Alzheimer’s disease mice – A new pharmacological target for Glu-related neurotoxicity

This study shows that ABCA7 deficiency amplifies glutamate excitotoxicity in Alzheimer's disease, highlighting a promising drug target.
ABCA7 deficiency exacerbates glutamate excitotoxicity in Alzheimer’s disease mice – A new pharmacological target for Glu-related neurotoxicity
Analytical investigation of metal distribution from e-cigarette aerosols to lung deposition using multi-platform mass spectrometry
ICPMSGCMSScientific article | Science and research

Analytical investigation of metal distribution from e-cigarette aerosols to lung deposition using multi-platform mass spectrometry

This study uses ICP-MS and LA-ICP-MS to track toxic metals from e-cigarette aerosols to lung tissue following exposure.
Analytical investigation of metal distribution from e-cigarette aerosols to lung deposition using multi-platform mass spectrometry
Determination of Flibanserin in Female Sexual Desire Enhancer Products by LC–MS/MS and Its Confirmation by LCMS-IT-TOF
LCMSScientific article | Science and research

Determination of Flibanserin in Female Sexual Desire Enhancer Products by LC–MS/MS and Its Confirmation by LCMS-IT-TOF

This study develops a rapid LC-MS/MS method for flibanserin analysis and finds little or no active ingredient in commercial female enhancer products.
Determination of Flibanserin in Female Sexual Desire Enhancer Products by LC–MS/MS and Its Confirmation by LCMS-IT-TOF
New material helps break down antibiotics in wastewater
LCMSArticle | Science and research

New material helps break down antibiotics in wastewater

Researchers developed a graphitic carbon nitride photocatalyst that efficiently degrades antibiotics and pharmaceutical residues in wastewater using visible light.
New material helps break down antibiotics in wastewater
From daily pills to one injection a year. HIV prevention pioneers visit IOCB Prague
GCMSICPMSLCMSArticle | Science and research

From daily pills to one injection a year. HIV prevention pioneers visit IOCB Prague

IOCB Prague hosted HIV prevention pioneers discussing lenacapavir, a long-acting drug that could shift HIV prevention from daily pills to a single yearly injection.
From daily pills to one injection a year. HIV prevention pioneers visit IOCB Prague
Cerebrospinal Fluid Proteome Reveals Dysregulation of Lysosomal and Axonal Proteins in Neurosyphilis
LCMSScientific article | Science and research

Cerebrospinal Fluid Proteome Reveals Dysregulation of Lysosomal and Axonal Proteins in Neurosyphilis

LC–MS/MS proteomics of cerebrospinal fluid reveals lysosomal and axonal pathway disruptions and potential biomarkers in neurosyphilis.
Cerebrospinal Fluid Proteome Reveals Dysregulation of Lysosomal and Axonal Proteins in Neurosyphilis
New blood biomarkers reveal how faithfully diabetes patients take metformin
LCMSArticle | Science and research

New blood biomarkers reveal how faithfully diabetes patients take metformin

Researchers from the Institute of Physiology CAS identified novel blood biomarkers that objectively reveal whether patients with type 2 diabetes take metformin as prescribed.
New blood biomarkers reveal how faithfully diabetes patients take metformin
Pesticides in House Dust: An Overlooked Pathway of Human Exposure
GCMSLCMSArticle | Science and research

Pesticides in House Dust: An Overlooked Pathway of Human Exposure

Pesticides in house dust? A RECETOX study reveals their presence in 93% of Czech homes, including legacy DDT residues and seasonal impacts from nearby agriculture.
Pesticides in House Dust: An Overlooked Pathway of Human Exposure
Integrated laser ablation and computed tomography: detecting the chemical footprint of microplastics and reconstructing 3D biological tissues
ICPMSScientific article | Science and research

Integrated laser ablation and computed tomography: detecting the chemical footprint of microplastics and reconstructing 3D biological tissues

This study integrates μCT and LA-ICP-MS to detect and reconstruct microplastics in tissues, combining structural imaging with chemical mapping.
Integrated laser ablation and computed tomography: detecting the chemical footprint of microplastics and reconstructing 3D biological tissues