MD-LC-MS for structure-function characterization of therapeutic antibodies (Jelle De Vos, MDCW 2025)
MD-LC-MS advances structural and functional analysis of mAbs, showing how post-translational changes impact FcRn/FcγR binding and antibody therapeutic performance.
Application of pearson correlation coefficient to HT-GC×GC-HRMS (Michelle Corbally, MDCW 2025)
Using HT-GC×GC-HRMS and Pearson correlation, 18 VGOs were ranked by properties, and key chemical differences were visualized across complex chromatograms.
Since the very first release of Mnova, we have been (and still are!) very fortunate to include in the software the prediction of NMR spectra provided by Modgraph Consultants.
Scoring of LC separation procedures for ezetimibe and its degradants using Mgears Chrom Best Method
Prof. Rafael Cela (Mestrelab) presents LC method selection with Mgears Chrom Best Method and how automation improves screening, analysis, reporting, and decisions.
TOF vs. Orbitrap for Intact Protein Structural Insights
Orbitrap-based MS revolutionizes intact protein analysis, surpassing TOF systems in resolution and robustness, enabling detailed glycoform studies and megaDalton protein insights.
Tackling PAH Analysis in Environmental Samples: Overcoming the Challenges with Advanced GC-MS Technology
PAH analysis in environmental samples is challenging, especially with strict regulations like EPA 8270E1. This blog explores how advanced GC-MS helps overcome these challenges.