Peptide Mapping Sample Preparation - Good Practices for Tryptic Digests
Best practices for sample preparation in peptide mapping with trypsin, covering denaturation, alkylation, buffer exchange, and protease selection for complete sequence coverage.
Learn how to efficiently open and manage chromatograms from measured sequences in Clarity software using overlay mode or batch loading via the chromatogram window.
Shedding Light on Trace-Level Impurity Detection in Modern GC Workflows
Explore how GC-LUMA leverages VUV detection to deliver sensitive, selective, and all-in-one GC analysis of impurities, solvents, and water—even in challenging pharma workflows.
Understanding PFAS and Combustion-Ion Chromatography
Learn how EPA Method 1621 and combustion-ion chromatography (C-IC) help detect PFAS by measuring adsorbable organic fluorine (AOF) in water with high accuracy and sensitivity.
A Method for Determination of Transport Efficiency in Laser Ablation Inductively Coupled Plasma Mass Spectrometry for Tissue Analysis
A novel LA-ICP-MS method uses upconversion nanoparticles to precisely measure transport efficiency, assessing effects of ablation wavelength, fluence, and cell design on accuracy.
Quantification of Endogenous Steroids and Hormonal Contraceptives in Human Plasma via Surrogate Calibration and UHPLC-MS/MS
A UHPLC-MS/MS assay using surrogate calibration and DMIS derivatization quantifies endogenous steroids and contraceptives in plasma with pg/mL sensitivity and regulatory-aligned validation.