ISC 2026 - Day 2

<h4>What if you could compress 179 days of grueling laboratory workflow into just 14 hours?</h4>In this episode of ‪ChromatographyTalk‬, ‪Organomation‬ General Manager David Oliva sits down with analytical chemist Laura Penabad to discuss her groundbreaking new research in biocatalysis and high-throughput screening. Evolving engineered enzymes typically requires checking thousands of variants—a massive bottleneck when traditional Liquid Chromatography-Mass Spectrometry (LC-MS) runs take minutes per sample. Laura reveals how her team built a modular screening platform that shatters this limitation, running samples 128 times faster than standard methods without sacrificing analytical accuracy.Laura breaks down the "orchestra" of technologies making this possible, including coupling nanoliter droplet microfluidics with Cyclic Ion Mobility-Mass Spectrometry (cIM-MS) to separate complex chemical isomers in milliseconds. She also shares the chaotic but triumphant behind-the-scenes stories of her PhD journey—from presenting a "comically bad" early poster at ASMS to recruiting an undergraduate mechanical engineer to build custom automation software from scratch.If you are an early-career researcher, a mass spec enthusiast, or curious about the future of synthetic biology and machine learning in chemistry, this episode is packed with invaluable intuition and advice.<h3>Video Transcription</h3><h4>From Months to Hours: Droplet Ion Mobility–MS for Biocatalysis Screening</h4>High-throughput screening is central to directed enzyme evolution, but conventional analytical workflows can create a difficult compromise: extremely fast screens often provide limited structural information, while techniques such as LC-MS offer much richer chemical insight at the cost of throughput. In a recent interview, analytical chemist Laura described how her work with droplet-based cyclic ion mobility mass spectrometry is helping bridge that gap—providing rapid analysis while retaining the ability to distinguish structurally similar products.Her research grew from an initially modest proof of concept into a screening platform capable of analyzing a 96-well plate in roughly ten minutes. The resulting workflow was approximately 128 times faster than a conventional three-minute LC-MS analysis, opening new possibilities for directed evolution campaigns in which thousands of enzyme variants need to be evaluated.<h4>Directed evolution needs better analytical screening</h4>Biocatalysis takes advantage of enzymes as highly selective catalysts capable of performing reactions under relatively mild conditions. Directed evolution extends those capabilities by deliberately modifying enzyme sequences, expressing large numbers of variants, screening their activity, and using the best-performing mutants as starting points for subsequent rounds of evolution.The process can be repeated multiple times, progressively steering an enzyme toward improved activity, altered substrate specificity, or even chemistry that does not occur naturally.But the effectiveness of directed evolution depends heavily on the screening step. The more variants that can be analyzed—and the more useful chemical information that can be collected for each one—the more effectively researchers can explore the enormous sequence space available to an enzyme.For Laura, this created a clear analytical challenge: develop a screening platform that was substantially faster than conventional chromatographic analysis without sacrificing the structural discrimination needed for chemically similar products.<h4>From an imperfect first experiment to a working platform</h4>The project did not begin with a polished high-throughput workflow.Laura recalled looking back at her 2023 ASMS poster, where the early system was still working with standards rather than true isomeric samples. Droplet introduction was slow—around six seconds per droplet—and the signals were far from the ideal reproducible, square, flat-topped profiles expected from replicate droplets.Nevertheless, simply producing a droplet signal represented an important first milestone.The decisive change came when the project stopped being treated merely as a demonstration that droplet ion mobility–MS could work and instead became a deliberate effort to build a robust screening platform.Laura approached the problem in modules. First came reliable droplet introduction. Then the ion mobility separation method. Quantification became another independent component. Matrix effects were introduced later, gradually making the system resemble the conditions expected with real screening samples.Each layer was tested before another was added.This stepwise strategy became one of the central principles of the project: rather than attempting to optimize the entire system simultaneously, individual components were developed, challenged, and then assembled into an increasingly realistic workflow.<h4>Finding the middle ground between speed and structural information</h4>One of the biggest analytical problems in high-throughput screening is distinguishing products with the same nominal or exact mass.Constitutional isomers may contain the same atoms and therefore generate the same mass-to-charge ratio, while differing only in how functional groups are arranged within the molecular structure. Very rapid optical or mass-based screens may therefore struggle to distinguish them.Traditional LC-MS can solve many of these problems through chromatographic separation, but a several-minute analysis rapidly becomes impractical when thousands of enzyme variants must be screened.Ion mobility offered Laura’s team another option.Rather than separating compounds on a chromatographic timescale, ion mobility can differentiate ions according to their gas-phase behavior on a much shorter timescale. In the workflow described in the interview, this created a useful compromise: not the kilohertz throughput possible with some simple screening technologies, but dramatically faster structural differentiation than conventional LC-MS.The goal was therefore not simply to achieve the fastest possible screen, but to find a middle-throughput analytical regime with enough resolving power to answer chemically meaningful questions.<h4>A 96-well plate in about ten minutes</h4>That strategy eventually produced one of the most striking results of the project.The droplet cyclic ion mobility–MS platform processed a 96-well plate in roughly ten minutes, while maintaining quantitative results comparable with the conventional LC-MS workflow used for comparison. According to the interview, this represented an approximately 128-fold increase in analysis speed relative to a three-minute LC-MS run.Laura described the successful plate experiment less as a surprise than as confirmation that the modular development strategy had worked.Before reaching that point, the workflow had already been challenged through a sequence of increasingly demanding experiments: droplet formation, ion mobility separation, calibration, matrix-containing calibration, and cross-testing analytes at different concentrations. By the time the complete plate was analyzed, each individual part of the analytical system had already been tested under progressively more realistic conditions.<h4>What does that speed mean for directed evolution?</h4>The impact becomes even clearer when the workflow is considered at the scale of an entire directed-evolution campaign.Laura’s manuscript estimated that a five-round campaign involving 5,000 variants would require approximately 179 days using the conventional LC-MS workflow but only about 14 hours using the new platform.Compressing months of analytical work into less than a day has consequences beyond laboratory productivity.It allows researchers to screen more enzyme variants and therefore sample a larger portion of sequence space. But the resulting datasets may also become increasingly valuable for computational approaches.Rather than retaining information only about the best-performing enzyme variant, researchers can preserve data describing variants that performed poorly as well as those that succeeded. When genotype and phenotype information remain linked through the well-plate workflow, these larger datasets can potentially provide richer input for machine-learning models designed to guide subsequent rounds of enzyme evolution.Faster analysis therefore does more than accelerate an existing experiment—it can change the scale and design of the experiment itself.<h4>Balancing ion mobility resolution and signal</h4>Increasing cyclic ion mobility separation time can improve resolution, but it also introduces an important trade-off: additional passes can reduce signal.Laura optimized this balance experimentally by continuously infusing mixtures containing both isomers and progressively adjusting the ion mobility conditions. After tuning parameters such as wave height and velocity, increasing the separation to three passes provided baseline resolution at the high analyte concentrations used during method development.<blockquote>Concentration, however, also mattered.</blockquote>At higher ion populations, space-charge effects could broaden peaks and reduce the baseline separation. This meant that the optimal number of passes could not be selected independently of the concentration range required by the final assay.Her broader advice for optimization is therefore application-driven: decide first what the analytical method actually needs to accomplish.More speed will almost always require sacrificing something—resolution, signal intensity, quantitative precision, or another performance parameter. The key is to identify which compromise the application can tolerate and then optimize the system around that requirement.<h4>Solving droplet carryover with a practical compromise</h4>Droplet-based workflows present their own engineering challenges, including carryover between neighboring samples.In Laura’s system, analytes showed little tendency to partition into the fluorinated oil separating aqueous droplets within the Teflon tubing. The more troublesome carryover occurred closer to electrospray ionization, where a small amount of sample could remain associated with the interface and appear when the next droplet arrived.Rather than adding excessive engineering complexity to an already elaborate platform, the researchers adopted a pragmatic solution: a sacrificial wash droplet between analytical samples.It is an example of a recurring theme throughout the project. The objective was not to construct the theoretically most sophisticated droplet system, but to create a screening workflow that remained sufficiently robust, reproducible, and practical for large numbers of samples.<h4>High-throughput analysis also requires high-throughput data processing</h4>Accelerating the mass spectrometry experiment created another bottleneck: the data.The instrument produced a continuous intensity-versus-time trace rather than a neatly organized well-plate dataset. With small experiments, Laura could manually identify individual droplets and process the results in spreadsheets. That approach quickly became unrealistic as sample numbers increased.The solution emerged through collaboration with an undergraduate mentee, Aiden, who helped develop a dedicated software tool for processing the continuous traces.Laura defined how the software should behave and how the analytical information should be organized, while Aiden developed the computational implementation. The workflow itself was subsequently adjusted to make automated data processing more reliable—for example, by introducing marker columns that allowed the software to recognize the end of each plate row.The resulting tool can accept the acquired traces together with information about plate dimensions and replicates and automatically return parameters including peak identity, duration, and the corresponding well position. A later version also generated an automatically populated heat map.The experience illustrates how improving analytical throughput often requires simultaneous development of instrumentation, experimental design, and informatics. Making the measurement faster is useful only if the resulting data can be processed at a comparable speed.<h4>Mentoring became part of the scientific process</h4>The software project also reflects another theme Laura emphasized throughout the interview: the value of mentoring.Several younger researchers contributed directly to the development of the final platform. Laura described mentees not simply as additional hands in the laboratory but as scientists capable of proposing their own hypotheses and experimental ideas.Working with undergraduate researchers also influenced the way she organized experiments.Because their available laboratory time was limited, each task needed to have a clear purpose. That encouraged a more disciplined approach to experimental planning: instead of performing experiments simply because they could be done, the team had to ask which experiment would most efficiently answer the next important question.In that sense, mentoring became another mechanism for improving the research itself.<h4>The next step: continuous, automated screening</h4>Despite the dramatic increase in analytical speed, the current workflow still includes manual operations such as loading tubing and connecting the sample stream to the mass spectrometer.The next engineering challenge is therefore automation.Laura described ongoing work using the Venturi effect to pull samples directly from wells into the droplet system. Building on previous work in the laboratory with 96-well plates, she has already tested this approach with as many as 2,000 samples.The long-term direction is clear: continuous and robust droplet generation, automated handling of thousands of samples, rapid ion mobility separation, mass spectrometric detection, and automated reconstruction of the resulting data into plate-based outputs.Combining those elements could move the system closer to the type of large-scale screening required for increasingly ambitious biocatalysis campaigns.<h4>Learning mass spectrometry one problem at a time</h4>Laura also reflected on the broader experience of developing the platform during her PhD.Ion mobility and mass spectrometry initially appeared intimidating, particularly because they combine concepts from analytical chemistry, physical chemistry, separations, instrumentation, and electrical engineering. What eventually changed was not simply learning more facts, but developing the ability to move repeatedly between theory and experiment.An unexpected result sends the researcher back to the underlying theory. A better understanding suggests a modified experiment. That experiment creates another observation, gradually building intuition about how the system behaves.Her advice to early-career scientists is therefore to accept that this process takes time.Advanced analytical techniques may initially appear overwhelming, but understanding develops incrementally through repeated interaction between theory, experimentation, failure, and refinement. Equally important, she emphasized the role of the supportive ion mobility–mass spectrometry community in making a technically demanding field more approachable for young researchers.From the first inconsistent droplets to a platform capable of processing thousands of samples, that iterative mindset ultimately shaped the entire project.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Droplet Cyclic Ion Mobility Mass Spec: Compressing Months of Enzyme Screening Into Just 14 Hours

ISC 2026 - Day 3

Article

Events

Video

Scientists

Interview

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer

Perform both basic and complex analyses with the Thermo Scientific™ GENESYS™ 30 Visible Spectrophotometer, an intuitive, reliable solution for education or in the lab.

<h3>Designed for Users, Designed for Results</h3>The Thermo Scientific ™ GENESYS ™ 30 is the most thoughtfully designed spectrophotometer available today. Its high resolution color display, large sample compartment, and data export options meet modern expectations for students, educators and lab technicians. The GENESYS 30 blends the simplicity to satisfy novice students with the capabilities that labs need for accurate quantitative analysis.<h4>System Benefits:</h4><ul><li>Large sample compartment with front access simplifies sample handling</li><li>High resolution color display</li><li>Outstanding durability in challenging environments thanks to:</li><li>Waterproof screen</li><li>Sealed, rubberized keypad</li><li>Removable, washable sample compartment</li><li>Sloping surfaces that shed spills</li><li>Chemical resistant PC-ABS covers</li><li>3A linear measurement range for concentrated solutions</li><li>Multi-point quant offers higher measurement confidence</li><li>Traditional monochromator paired with advanced electronics delivers outstanding stability</li><li>Scan mode for spectral analysis and interpretation</li><li>Data any way you want it - excellent snap-on thermal printer or USB data export</li><li>Expanded capabilities with optional VISIONlite software</li><li>2-year warranty</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_4_4442fcccc5.jpg" alt="Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_4_4442fcccc5.jpg 195w," sizes="100vw" width="2103" height="1685"><h3>Modern Power meets Traditional Simplicity</h3><h4>Live Display and Concentration Mode</h4>Replicate the familiar display of absorbance or transmittance, and single standard concentration measurements of prior generation instruments in the GENESYS 30 Live Display mode. All your parameters are set and kept in view on a single screen as the calculated concentration updates every two seconds.<h4>Fixed Mode</h4>Apply a factor to an absorbance measurement at one wavelength, or measure at two wavelengths with two factors and perform addition, subtraction or division of the values. Display results for up ten samples then print, save or clear your data before going on to the next sample series.<h4>Quantitative Analysis with up to Six Standards</h4>Go beyond the basic spectrophotometer by recording and storing up to six standards to calibrate your method. Choose a linear fit with an intercept or forced through zero. Name and save your method on the instrument or back it up to a USB memory device. All data are recorded with an index number (S1 – S10) and a time stamp. The result table accommodates up to ten samples for you to print or save before going on to the next sample series or analysis.<h4>Go negative!</h4>Some methods call for blanking the instrument on a dark standard and reading absorbance in the negative range. Most single beam instruments cannot measure below -0.3A. GENESYS 30 uses advanced signal processing to deliver stable, reliable results down to -3A.<h4>Simple to Sophisticated:</h4>The GENESYS 30 has the flexibility to perform routine analysis one minute and complex analytical methods the next. The custom Analyzer mode enables you to build your formula with up to six wavelengths, six factors, standard arithmetic operators and absorbance values raised to the 2nd or 3rd power. Use the included Windows® application to design your method. Transfer the method to your GENESYS 30 and run it with the touch of a button. Analyzer mode shows your method name and a continuous display of your results. Technicians can write the result down or print it with a time stamp using the printer accessory.<h4>Smarter by Design:&nbsp;</h4>GENESYS 30 offers the convenient SmartStart™ feature that has delighted GENESYS 10S users since its introduction. The SmartStart menu gives you direct access to your 12 favorite methods. Allowing you to work smarter, not harder.<h4>Snap on Printer:&nbsp;</h4>Fast and clear printing when you need it. Add printing capability to your instrument. The snap-on thermal printer installs in moments.&nbsp;<h4>Quick and Simple Lamp Replacement:&nbsp;</h4>No need to remove the cover, just loosen two screws, slide out the old lamp fitting and slide a new one back in. Everything is pre-aligned, just let the new lamp warm up and go back to work.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_3_82082740d3.jpg" alt="Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer: Quick and simple lamp replacement." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_3_82082740d3.jpg 197w," sizes="100vw" width="1737" height="1376"><h3>At Home in the Instructional Laboratory</h3>GENESYS spectrophotometers are core teaching instruments in chemistry and biology laboratories around the world. The Thermo Scientific™ GENESYS™ 30 allows students and teachers to focus on examining scientific data and learning scientific concepts instead of learning instrumentation.<h4>Easy to Teach, Easy to Learn&nbsp;</h4>Clearly labeled, uniquely colored keys simplify instrument operation. New users require little or no training.<h4>Get Working – Faster!</h4>Large, color digital screen and numeric keypad help you set up methods faster. Simplified software interface gives users maximum control and efficiency.<h4>Designed for Today, Built for Tomorrow – Inside and Out!</h4>On the inside, GENESYS 30 uses advanced optics, electronics and signal processing to deliver superior measurement performance for its class. On the outside, GENESYS 30 presents a tough exterior built to last for years in the most demanding environments.<ul><li>Resistant to spills</li><li>Removable and washable sample compartment</li><li>The sample compartment lid<ul><li>stays where you put it - open or closed</li><li>has a magnetic latch to hold it closed during measurements</li><li>is customer-replaceable should it get broken through abuse</li></ul></li></ul><h4>Simple and Familiar</h4>Open the Live Display application with a single button-press to monitor the absorbance or transmittance live – just like a GENESYS 20 or SPECTRONIC 20. The spectrum indicator shows the color of light being absorbed.<h4>Special support for OD 600 and test-tube measurements</h4>For measurements in test-tubes, the test-tube holder accessory accommodates 100mm x 13mm test-tubes with the lid closed. Or add the tall test-tube adaptor to use larger diameter, taller tubes (up to 150mm, 6 inches) with the lid open. Special OD600 mode for cell growth measurements. Select it from the Home menu and go! No method setup required.<h4>Scanning: Simple and Fast</h4>Find peaks in the spectrum of your sample by scanning across the spectrum in any range from 325nm to 1100nm with 1nm precision and noise-free peaks up to 3A. Use the cursor and zoom controls to identify λmax.<h4>Data you can use</h4><ul><li>Print your scan and stick it into a lab notebook using the printer accessory and optional self-stick printer paper.</li><li>Save the data points of your scan to a USB memory device and load the data into a spreadsheet or graphing program for optimal reporting.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Genesys_30_USB_stick_A_c45fd86787.jpg" alt="Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer: USB stick." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_Genesys_30_USB_stick_A_c45fd86787.jpg 181w," sizes="100vw" width="543" height="469"><h3>VISIONlite Software</h3>For users who need the power of computerized data analysis, optional Thermo Scientific™ VISIONlite™ software pairs a simple user interface with a wider range of options for experiment design and data analysis.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific - Genesys spectrophotometers: VISIONlite Software." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h4>Scan Application:</h4><ul><li>Automated peak pick and label</li><li>Overlay spectra and print the results</li></ul><h4>Kinetics Application:</h4><ul><li>Data intervals as low as 1 second</li><li>Enzyme rate calculation with factor</li></ul><h4>Quantitative Analysis:</h4><ul><li>Up to 100 standards</li><li>Linear, quadratic or cubic data fits</li></ul><h4>Performance Verification:</h4><ul><li>Full suite of tests to verify performance of your instrument</li><li>Pre-loaded pass/fail limits specific to your instrument</li></ul><h3>GENESYS 30 Accessories</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_59d912ddd3.jpg" alt="Thermo Scientific™ GENESYS™ 30 Vis Spectrophotometer: GENESYS 30 Accessories." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_GENESYS_30_Vis_Spectrophotometer_59d912ddd3.jpg 243w," sizes="100vw" width="1444" height="929"><h3>GENESYS 30 Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: &lt;0.003 A, 325 to 1000 nm smoothed</li><li>Compartments:&nbsp;<ul><li>Accessible from top, front or side</li><li>Able to accommodate cells up to 100mm pathlength</li><li>Available accessory for test-tubes up to 25mm diameter and 150mm height</li><li>Removable, washable sample compartment liner with magnetic placement and hold-down</li></ul></li><li>Connections: USB-A, USB-B</li><li>Description: GENESYS 30 VIS Spectrophotometer with EU Power Cable</li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: &lt;0.002 A/hr. (At 500 nm after 2 hr. warmup.) Typical &lt;0.004 A/hr. after 1 hr. warmup</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/250 V, 50/60 Hz</li><li>Keypad: Tactile rubber 23 keys with numeric keypad</li><li>Lamp Life: 1000 hrs.</li><li>Noise: (RMS at 500nm. 60 consecutive measurements)<ul><li>≤0.001A at 0A</li><li>≤0.001A at 1A</li><li>≤0.002A at 2A</li></ul></li><li>Optical Design: Single Beam</li><li>Photometric Accuracy: ±0.002 A (0 to 0.3 A), 0.5% of ABS reading (0.301 A to 2.5 A)</li><li>Photometric Display: -3A to +3A, 0 to 200 000 %T, 0 to 9 999 999 C</li><li>Photometric Range: -3A to +3A</li><li>Photometric Repeatability: ± 0.002 A (Measured at 1.0 A at 546 nm)</li><li>Printer Included: Thermal printer accessory with 80 mm width paper</li><li>Scan Speed: Automatic – up to 1200 nm/min.</li><li>Stray Light: &lt;0.1%T at 340 nm and 400 nm</li><li>Measured using glass cutoff filters or NaNO₂ at 340 nm</li><li>Warranty: 2 years standard with 1 year extension upon registration of the instrument with Thermo Fisher Scientific within 6 months of purchase</li><li>Wavelength Accuracy: ±2 nm</li><li>Wavelength Data Interval: 1 nm</li><li>Wavelength Repeatability: &lt; ±1 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Silicon Photodiode</li><li>Display: 5 in. 32-bit Color Display, 800 x 480 pixels</li><li>Languages: English, French, German, Spanish, Italian, Portuguese, Russian, Chinese, Japanese, Korean, Thai, Arabic</li><li>Wavelength Range: 325 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 40 Vis Spectrophotometer

Perform routine measurements for quality control or teaching in the chemistry classroom with rugged Thermo Scientific™ GENESYS 40 Vis Spectrophotometer.

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 40 Vis Spectrophotometer</h3>For teaching labs, research labs and industrial QC requiring robust construction, ease-of-use and software capability.<h5>Advanced usability, modern functionality</h5><ul><li>7-inch, high-resolution touchscreen interface</li><li>Local control increases speed and reliability for routine analysis</li><li>Large sample compartment with front access simplifies sample handling</li><li>Wi-Fi ready - save data and methods, print results from on-board control</li></ul><h5>Designed for</h5><ul><li>Chemistry labs</li><li>Routine measurements</li><li>Moderate throughput requirements</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Genesys_40_Kyveta_A_7955a6a01a.jpg" alt="Thermo Scientific™ GENESYS™ 40 Vis Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_Genesys_40_Kyveta_A_7955a6a01a.jpg 234w," sizes="100vw" width="1536" height="1024"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific GENESYS Spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 40 Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.005 A</li><li>Compartments:&nbsp;<ul><li>Accessible from top, front or side</li><li>Able to accommodate cells up to 100mm cells</li><li>Available accessory for test tubes up to 25 mm diameter and 150 mm height</li><li>Removable, washable sample compartment liner with magnetic placement and hold-down</li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available&nbsp;</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0010 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Includes: GENESYS 40 Spectrophotometer</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt;1000 hrs.</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Dual Beam</li><li>Photometric Accuracy: ±0.002 A at 0.5 A, ±0.004 A at 1.0 A, ±0.008 A at 2.0 A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –3A to +3.5A</li><li>Photometric Repeatability: ±0.001A at 1A measured at 1.0A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Automatic – up to 1800 nm/min.</li><li>Stray Light: &lt;0.05%T at 340 nm and 400 nm</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Fixed, 800 x 1280 pixels</li><li>Light Source: Tungsten Halogen</li><li>Spectral Bandwidth: 5 nm</li><li>Wavelength Range: 325 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 140 Vis Spectrophotometer

Perform quantitative measurements in routine industrial QA/QC or university chemistry labs with the automated and network-capable Thermo Scientific™ GENESYS 140 Vis Spectrophotometer.

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 140 Vis Spectrophotometer</h3>For advanced teaching labs, R&amp;D, research and life science applications requiring higher throughput or temperature control.<h5>Elite performance, enhanced capabilities</h5><ul><li>7-inch, high-resolution touchscreen interface</li><li>Local control increases speed and reliability for routine analysis</li><li>Large sample compartment with front access simplifies sample handling</li><li>Wi-Fi ready - save data and methods, print results from on-board control</li></ul><h5>Designed for</h5><ul><li>Chemistry labs</li><li>Routine measurements</li><li>Moderate throughput requirements</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_140_titul_B_bd2a19cbcb.jpg" alt="Thermo Scientific GENESYS Spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_140_titul_B_bd2a19cbcb.jpg 225w," sizes="100vw" width="516" height="358"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific: Genesys spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 140 Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.005 A</li><li>Compartments: Accommodates (optional):<ul><li>8-position cell changer</li><li>4-position cell changer (long path cells)</li><li>Peltier thermostatted cell holder (20–60 °C)</li><li>Sipper accessory</li><li>Fiber optic probe coupler</li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available&nbsp;</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0010 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Includes: Genesys 140 Spectrophotometer</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt;1000 hrs.</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Dual Beam</li><li>Photometric Accuracy: ±0.002A at 0.5A, ±0.004A at 1.0 A±0.008 A at 2.0A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –3A to +3.5A</li><li>Photometric Repeatability: ±0.001 A at 1 A measured at 1.0 A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Automatic – up to 1800 nm/min.</li><li>Stray Light: &lt;0.05%T at 340 nm and 400 nm</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Tiltable, 800 x 1280 pixels</li><li>Light Source: Tungsten Halogen</li><li>Spectral Bandwidth: 5 nm</li><li>Wavelength Range: 325 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 50 UV-Vis Spectrophotometer

Perform routine measurements for quality control or teaching in the chemistry classroom with rugged Thermo Scientific™ GENESYS 50 UV-Vis Spectrophotometer.

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 50 UV-Vis Spectrophotometer</h3>For teaching labs, research labs and industrial QC requiring robust construction, ease-of-use and software capability.<h5>Advanced usability, modern functionality</h5><ul><li>7-inch, high-resolution touchscreen interface</li><li>Local control increases speed and reliability for routine analysis</li><li>Large sample compartment with front access simplifies sample handling</li><li>Wi-Fi ready - save data and methods, print results from on-board control</li></ul><h5>Designed for</h5><ul><li>Chemistry labs</li><li>Routine measurements</li><li>Moderate throughput requirements</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Genesys_50_Kyveta_bae9677ae0.jpg" alt="Thermo Scientific™ GENESYS™ 50 UV-Vis Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_Genesys_50_Kyveta_bae9677ae0.jpg 188w," sizes="100vw" width="534" height="443"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific GENESYS Spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 50 UV-Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.002 A</li><li>Compartments:&nbsp;<ul><li>Accessible from top, front or side</li><li>Able to accommodate cells up to 100 mm cells</li><li>Available accessory for test-tubes up to 25 mm diameter and 150 mm height</li><li>Removable, washable sample compartment liner with magnetic placement and hold-down</li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0005 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Includes: GENESYS 50 Spectrophotometer</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt; 5 years typical, 3 years guaranteed</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Dual Beam</li><li>Photometric Accuracy: ±0.002A at 0.5A, ±0.004A at 1.0A, ±0.008 A at 2.0 A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –2A to +3.5A</li><li>Photometric Repeatability: ±0.001 A at 1 A measured at 1.0 A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Slow, medium and fast – up to 1600 nm/min.</li><li>Stray Light: &lt; 1.0%T 198 nm (KCl) , &lt;0.05%T at 220 nm (NaI), &lt;0.03%T at 340 nm (NaNO2)</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Fixed, 800 x 1280 pixels</li><li>Spectral Bandwidth: 2 nm</li><li>Wavelength Range: 190 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 150 UV-Vis Spectrophotometer

Perform quantitative measurements in routine industrial QA/QC or university chemistry labs with the automated and network-capable Thermo Scientific™ GENESYS 150 UV-Vis Spectrophotometer.

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 150 UV-Vis Spectrophotometer</h3>For advanced teaching labs, R&amp;D, research and life science applications requiring higher throughput or temperature control.<h5>Elite performance, enhanced capabilities</h5><ul><li>7-inch, high-resolution touchscreen interface</li><li>Local control increases speed and reliability for routine analysis</li><li>Large sample compartment with front access simplifies sample handling</li><li>Wi-Fi ready - save data and methods, print results from on-board control</li></ul><h5>Designed for</h5><ul><li>Chemistry labs</li><li>Routine measurements</li><li>Moderate throughput requirements</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_150_titul_B_a202c02cea.jpg" alt="Thermo Scientific™ GENESYS™ 150 Uv-Vis Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_150_titul_B_a202c02cea.jpg 180w," sizes="100vw" width="415" height="360"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific: Genesys spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 150 UV-Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.002 A</li><li>Compartments: Accommodates (optional):<ul><li>8-position cell changer</li><li>4-position cell changer (long path cells)</li><li>Peltier thermostatted cell holder (20–60 °C)</li><li>Sipper accessory</li><li>Fiber optic probe coupler</li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0005 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Includes: Genesys 150 Spectrophotometer</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt; 5 years typical, 3 years guaranteed</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Dual Beam</li><li>Photometric Accuracy: ±0.002A at 0.5A, ±0.004A at 1.0A, ±0.008 A at 2.0 A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –2A to +3.5A</li><li>Photometric Repeatability: ±0.001 A at 1 A measured at 1.0 A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Slow, medium and fast – up to 1600 nm/min.</li><li>Stray Light: &lt; 1.0%T 198 nm (KCl) , &lt;0.05%T at 220 nm (NaI), &lt;0.03%T at 340 nm (NaNO2)</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Tiltable, 800 x 1280 pixels</li><li>Spectral Bandwidth: 2 nm</li><li>Wavelength Range: 190 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ GENESYS™ 180 UV-Vis Spectrophotometer

Perform high throughput quantitative UV-Vis measurements where a double beam is required as a reference cell position with the  Thermo Scientific™ GENESYS™ 180 UV-Visible Spectrophotometer. 

<h4>GENESYS - developed for users, designed for results</h4>Built on the foundation of 60 years of spectroscopy experience, the next generation Thermo Scientific™ GENESYS™ family of Vis/UV-Vis spectrophotometers provides exceptional performance with a contemporary design.<ul><li>Start taking measurements immediately with the simple-to-use, high-resolution, color-display start menu</li><li>Exchange samples with ease with large, accessible sample compartment</li><li>Save your data fast any way you want it with multiple data-export options</li></ul>There is a GENESYS spectrophotometer you can count on to provide accurate, reproducible results for your application requirements.<h3>GENESYS 180 UV-Vis Spectrophotometer</h3>For laboratories requiring double beam with a reference cell position.<h5>High-throughput ready</h5><ul><li>Double-beam optics</li><li>Ideal solution when a reference beam is required, such as for kinetics</li><li>8-cell changer standard</li><li>Make measurements outside the sample compartment without cuvettes using fiber optic coupler and probe</li></ul>Designed for laboratories requiring double beam operation with a reference cell position.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_180_titul_D_open_90df06abb8.jpg" alt="Thermo Scientific™ GENESYS™ 180 UV-Vis Spectrophotometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Thermo_Scientific_vis_spektrofotometr_genesys_180_titul_D_open_90df06abb8.jpg 171w," sizes="100vw" width="467" height="427"><h3>Walk-up convenience</h3>Simple-to-use, touchscreen user interface features the methods and applications most important to you.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg" alt="Thermo Scientific Genesys spectrophotometers" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Genesys_spectrophotometers_ae282fe726.jpg 239w," sizes="100vw" width="1422" height="928"><h5>Flexible computer control</h5>Optional VISIONlite software offers complete control from a Microsoft ® Windows ® computer providing applications for:<ul><li>Scanning</li><li>Quantitative analysis</li><li>Kinetics</li><li>Fixed wavelength measurements</li></ul><h3>GENESYS 180 UV-Vis Spectrophotometer Specifications</h3><ul><li>Baseline Flatness: ±0.002 A</li><li>Compartments:<ul><li>8-position cell changer (standard)</li><li>Also accommodates (optional):<ul><li>4-position cell changer (long path cells)</li><li>Peltier thermostatted cell holder (20–60 °C)</li><li>Sipper accessory</li><li>Fiber optic probe coupler</li></ul></li></ul></li><li>Connections:&nbsp;<ul><li>Single USB-A</li><li>Duplex USB-A</li><li>Export data to network or PC via USB, Ethernet, or Wi-Fi USB adaptor, available</li><li>Print via USB, Ethernet or Wi-Fi USB adaptor available</li></ul></li><li>Dimensions (L x W x H): 35.5 x 38.5 x 19.5 cm</li><li>Drift: (At 500 nm after 1 hour warmup) &lt;0.0005 A/hr.</li><li>Electrical Requirements: External AC to DC converter. Voltage and Frequency (Hz) selected automatically, 100/240 V, 50/60 Hz</li><li>Keypad: Touchscreen</li><li>Lamp Life: &gt; 5 years typical, 3 years guaranteed</li><li>Noise: (RMS at 500 nm 60 consecutive measurements)<ul><li>≤0.00020A at 0A at 260 and 500 nm</li><li>≤0.00030A at 1A at 260 and 500 nm</li><li>≤0.00040A at 2A at 260 and 500 nm</li></ul></li><li>Optical Design: Double Beam</li><li>Photometric Accuracy: ±0.002A at 0.5A, ±0.004A at 1.0A, ±0.008 A at 2.0 A</li><li>Photometric Display: -3A to +5A</li><li>Photometric Range: –2A to +3.5A</li><li>Photometric Repeatability: ±0.001 A at 1 A measured at 1.0 A at 546 nm</li><li>Printer Included: Snap-on printer available</li><li>Scan Speed: Slow, medium and fast – up to 1600 nm/min.</li><li>Stray Light: &lt; 1.0%T 198 nm (KCl) , &lt;0.05%T at 220 nm (NaI), &lt;0.03%T at 340 nm (NaNO2)</li><li>Warranty: 2 yrs std + 1 yr ext upon reg</li><li>Wavelength Accuracy: ±0.5 nm</li><li>Wavelength Data Interval: 0.1 nm, 0.2 nm, 0.5 nm, 1 nm, 2 nm, 5 nm</li><li>Wavelength Repeatability: &lt; ±0.2 nm</li><li>Weight (Metric): 7.5 kg</li><li>Detector Type: Dual Silicon Photodiodes</li><li>Display: 7 in. High Definition Color Touchscreen, Tiltable, 800 x 1280 pixels</li><li>Spectral Bandwidth: 2 nm</li><li>Type: UV-Vis Spectrophotometer</li><li>Wavelength Range: 190 to 1100 nm</li><li>Unit Size: Each</li></ul>

Thermo Scientific BioMate 160 UV-Vis Spectrophotometer

Perform quantitative measurements in life science laboratories with the automated and network-capable Thermo Scientific™ BioMate™ 160 UV-Visible Spectrophotometer. 

Perform quantitative measurements in life science laboratories with the automated and network-capable Thermo Scientific™ BioMate™ 160 UV-Visible Spectrophotometer. The BioMate 160 Spectrophotometer offers pre-programmed assay methods for nucleic acid and protein concentration as well as cell culture measurements. Optimized for usability and performance, this platform features a high-resolution color touchscreen, optional Wi-Fi networking, and a rugged design.The BioMate UV-Vis Spectrophotometer provides automation for high-throughput options and room-light resistance, allowing lid-open operation for improved speed and convenience. Software includes pre-programmed life science methods such as Nucleic Acid A260; Protein A280 and A205; Protein Colorimetric assays and OD600.A full line of accessories, including automated cell changers and cell holders, sipper, and fiber optic probes are designed to simplify sampling and accommodate high throughput measurements and temperature control.<h5>Features:</h5><ul><li>7-inch high-resolution touchscreen user interface</li><li>Pre-programmed life science methods</li><li>Networking capable (Wi-Fi adaptor available)</li><li>Room light resistance for 'open-lid' operation</li><li>Sipper accessory</li><li>Removable, washable sample compartment liner with magnetic placement and hold-down</li><li>Accommodates cells up to 100 mm pathlength</li><li>(Optional) 8-position cell changer with switchable turret</li><li>(Optional) 4-position cell changer (long path cells)</li><li>(Optional) Peltier-thermostatted single cell holder (20 °C - 60 °C)</li></ul><h5>Designed for:</h5><ul><li>Advanced teaching labs</li><li>R&amp;D departments</li><li>Applications requiring high throughput or temperature control</li></ul><h4>Specifications</h4>Instrument Type: UV-Visible Spectrophotometer Optical Design: Dual beam Wavelength Range: 190–1100 nm Spectral Bandwidth: 2 nm Photometric Range: –2 A to +3.5 A Photometric Accuracy: ±0.002 A at 0.5 A, ±0.004 A at 1.0 A, ±0.008 A at 2.0 A Photometric Repeatability: ±0.001 A at 1 A (546 nm) Photometric Display: –3 A to +5 A Noise (RMS at 500 nm):<ul><li>≤0.00020 A at 0 A</li><li>≤0.00030 A at 1 A</li><li>≤0.00040 A at 2 A Drift: &lt;0.0005 A/hr at 500 nm after 1-hour warmup Baseline Flatness: ±0.002 A Stray Light:</li><li>&lt;1.0%T at 198 nm (KCl)</li><li>&lt;0.05%T at 220 nm (NaI)</li><li>&lt;0.03%T at 340 nm (NaNO₂)</li></ul><h5>Wavelength Performance</h5><ul><li>Accuracy: ±0.5 nm</li><li>Repeatability: ±0.2 nm</li><li>Data Interval Options: 0.2, 0.5, 1, 2, 5 nm</li><li>Scan Speed: Slow, medium, fast (up to 1600 nm/min)</li></ul><h5>Display &amp; User Interface</h5><ul><li>Touchscreen: 7 in. high-definition color, tiltable (800 × 1280 px)</li><li>Keypad: Touchscreen interface</li></ul><h5>Connectivity &amp; Data Handling</h5><ul><li>Connections: Single USB-A, Duplex USB-A</li><li>Data Export: USB, Ethernet, Wi-Fi adaptor (optional)</li><li>Printer Support: Snap-on printer (optional), USB/Ethernet/Wi-Fi printing available</li></ul><h5>Sample Compartment Compatibility (Optional Accessories)</h5><ul><li>8-position or 4-position cell changers</li><li>Long path cell changer</li><li>Peltier thermostatted cell holder (20–60 °C)</li><li>Sipper accessory</li><li>Fiber optic probe coupler</li></ul><h5>General Specifications</h5><ul><li>Lamp Life: &gt;5 years typical, 3 years guaranteed</li><li>Detector Type: Dual silicon photodiodes</li><li>Dimensions (L × W × H): 35.5 × 38.5 × 19.5 cm</li><li>Weight: 7.5 kg</li><li>Power Requirements: 100–240 V, 50/60 Hz (auto-selecting via external AC–DC converter)</li><li>Certifications: Certificate of Analysis (COA), Certificate of Conformance (COC)</li><li>Warranty: 2 years standard + 1-year extension upon registration</li><li>Unit Size: Each</li></ul>

Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system

The Inuvion Core system gives you all the benefits of chemical suppression and higher-pressure operation, with manual eluent preparation.

<h3>Welcome to the evolution of everyday IC reliability</h3>The new Thermo Scientific™ Dionex™ Inuvion™ ion chromatography system makes ion analysis simpler and more intuitive than ever before. And it delivers exactly what a busy analytical testing lab is looking for: consistently excellent results-every shift, every day, for every operator.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_2_6400708696.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ ion chromatography system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_2_6400708696.jpg 245w," sizes="100vw" width="825" height="498"><h3>Start with Inuvion Core</h3>The Inuvion Core system gives you all the benefits of chemical suppression and higher-pressure operation, with manual eluent preparation. You still enjoy the same robust Dionex Inuvion platform-easily configurable and economically upgradeable to full-featured capabilities as budget allows.<figure class="image"><img style="aspect-ratio:650/650;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Dionex_Inuvion_Core_ion_chromatography_system_6c8824cb1d.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Dionex_Inuvion_Core_ion_chromatography_system_6c8824cb1d.jpg 156w," sizes="100vw" width="650" height="650"></figure><h3>SIMPLE, INTUITIVE USER EXPERIENCE&nbsp;</h3><ul><li>Smart, function-driven design lets you quickly and safely access everything on the instrument—no hard-to-reach compartments, and no step stools or extra tools needed!</li><li>Automated startup and shutdown routines ensure the system is quickly ready for the day’s work without user intervention.&nbsp;</li><li>Built-in how-to videos reduce training time and simplify setup and operation.</li></ul><h3>ULTRA-RELIABLE PERFORMANCE&nbsp;</h3><ul><li>Advanced high-performance pump technology and electronics let you take advantage of a wider range of columns and chemistries to improve the speed and quality of your results.</li><li>Fast, flexible, convenient electrolytic suppression: Just connect the suppressor; no external pump or offline conditioning needed for regeneration.</li><li>Reagent-free IC (RFIC™) capability makes eluent preparation as simple as “just add water,” while ensuring more consistent results and enabling optimized gradient separations.</li></ul><h3>EASILY CONFIGURABLE AND UPGRADEABLE</h3><ul><li>Versatile, adaptable platform lets you configure the exact Dionex Inuvion IC system for today’s needs and budget, with confidence that your system will also meet your future needs.</li><li>Multiple options and peripherals extend IC capabilities, letting you easily—and cost-effectively—adapt to changing sample types and workflow requirements.</li></ul><h3>Simply the best system for everyday ion analysis</h3><figure class="image"><img style="aspect-ratio:1107/755;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_d855feb2a8.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ ion chromatography system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_d855feb2a8.jpg 229w," sizes="100vw" width="1107" height="755"></figure>1. Operator-friendly engineering saves time and reduces errors by allowing easy, unobstructed access to all components, connections and consumables2. Compact design helps you make the most of valuable bench space3. Digital gas pressure regulator increases precision of gas delivery for maximum day-to-day consistency (optional)4. Temperature-controlled conductivity cell improves reproducibility and ensures baseline stability5. Vacuum degassing capability enables more consistent peak identification from smoother baselines6. Seal wash pump reduces maintenance costs when using manually prepared eluents (optional)&nbsp;7. Reagent-free IC (RFIC) saves time and ensures greater day-to-day and operator-to-operator consistency, while also allowing the use of gradient separations8. Electrolytic suppression entirely eliminates the need for manual regenerant preparation (or, opt for a continuously regenerated, always- ready-to-go chemical suppressor)9. Thermo Scientific™ Dionex™ IC PEEK Viper™ fittings ensure confident, low dead volume connections every time—no tools required! (optional)10. Integrated column heater minimizes the impact of fluctuations in lab temperature that can adversely affect results (optional)11. 6- or 10-port auxiliary valve lets you automate in-line sample preparation12. State-of-the-art high-pressure pump (up to 5000 psi) lets you increase flow rates with smaller particle columns to reduce run times or add additional separation capacity with longer column length13. System self-diagnostics automatically detect any issues with hardware and consumables14. Self-service capabilities and user-swappable parts help you get back up and running in a hurry Automatic eluent monitor alerts the operator to low solution levels, avoiding potential system damage or failed runs (optional)15. Automatic eluent monitor alerts the operator to low solution levels, avoiding potential system damage or failed runs (optional)<h3>Flexible, adaptable Dionex Inuvion platform</h3>You can configure your Dionex Inuvion system to meet specific analytical and budget requirements, and easily reconfigure as needed. Multiple configurations and peripherals extend IC capabilities, letting you easily-and cost-effectively-adapt to changing sample types and workflow requirements.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_3_fa8233bcd4.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ ion chromatography system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_3_fa8233bcd4.jpg 245w," sizes="100vw" width="1246" height="572"><h3>Consistently excellent results every day</h3>The Dionex Inuvion IC system supports a full range of columns to improve the speed and quality of results, for both anions and cations. Expanded capabilities, such as Reagent-Free IC (RFIC), enhance operator-to-operator consistency, while enabling the use of eluent gradients to optimize separations.<h4>Rapid results</h4><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Obr_2_Ukazka_rychle_separace_zakladnich_aniontu_s_uhlicitanovou_MF_Zkraceni_doby_analyzy_diky_typu_kolony_a_vyssimu_prutoku_0e610b919d.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system: Figure 1. Elution of seven common inorganic anions using carbonate eluent. Short columns and fast flow rates let you reduce run times." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Obr_2_Ukazka_rychle_separace_zakladnich_aniontu_s_uhlicitanovou_MF_Zkraceni_doby_analyzy_diky_typu_kolony_a_vyssimu_prutoku_0e610b919d.jpg 245w," sizes="100vw" width="1622" height="739"><h4>Exceptional reproducibility</h4><figure class="image"><img style="aspect-ratio:1693/754;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Obr_3_Ukazka_reprodukovatelnosti_analyzy_zakladnich_aniontu_40_nastriku_Spickova_technologie_cerpadla_a_elektronika_pristroje_poskytuji_konzistentni_a_reprodukovatelne_vysledky_f66e7430cf.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system: Figure 2. Overlay of 40 replicate injections. State-of-the-art pump technology and Electronics deliver consistent, reproducible results." width="1693" height="754"></figure><h4>Increased sensitivity and consistency</h4><figure class="image"><img style="aspect-ratio:1860/836;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Obr_4_Ukazka_vysoce_citlive_analyzy_aniontu_ve_vodach_Eluent_generator_KOH_a_elektrolyticka_suprese_snizuji_pozadi_cimz_dochazi_ke_zvyseni_citlivosti_da55facfd0.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system: Figure 3. Determination of inorganic anions in drinking and surface waters. KOH eluent generation and electrolytic suppression yield lower backgrounds for greater sensitivity and increased day-to-day consistency." width="1860" height="836"></figure><h4>Method optimization</h4><figure class="image"><img style="aspect-ratio:1799/889;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Obr_5_Ukazka_optimalizace_metody_zkraceni_doby_analyzy_pouzitim_gradientu_mobilni_faze_fc1fbe9cb0.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system: Figure 4. Comparison of isocratic and gradient runs using eluent generation. Reduce run length and sharpen later-eluting peaks with the same ease as an isocratic run with no need for two separate eluents or a proportioning pump." width="1799" height="889"></figure><h3>Compliance-ready Chromeleon CDS</h3>A trusted industry standard all over the world, ”Simply Intelligent” <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software </a>brings out the full power of the Dionex Inuvion IC system. Easy to learn and easy to use, it automates and optimizes daily tasks and helps even inexperienced users achieve consistent, high quality results.<img style="aspect-ratio:3700/1660;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Thermo_Scientific_Dionex_Inuvion_2_303a6eb73b.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system." width="3700" height="1660">

Thermo Scientific™ LipidSearch™ Software

Thermo Scientific™ LipidSearch™ software provides accurate identification of lipids and automatically integrates complex data into a concise report.

<h3>The promise of lipidomics</h3>Lipidomics is a new field of study crucial for understanding cellular physiology and pathology. The application of lipidomic profiling to disease phenotype analysis is a rapidly growing aspect of translational medical research. Identification of unique lipid biomarkers has the potential to distinguish healthy individuals from individuals at risk for disease, detect diseases earlier, and facilitate development of personalized treatments.Liquid chromatography combined with mass spectrometry (LC/MS) is a widely adopted technique for lipidomics analyses. Relative and absolute quantitation, and identification, of lipids from biological samples requires sophisticated software with an extensive, comprehensive database. Thermo Scientific™ LipidSearch™ software provides accurate identification of lipids and automatically integrates complex data into a concise report. With its easy-to-use web-based interface, it dramatically reduces data analysis time.<figure class="image"><img style="aspect-ratio:915/494;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_2_73b7d0a9e2.jpg" alt="Thermo Scientific™ LipidSearch™ Software: Easy-to-use web browser interface for automated and reliable identification." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_2_73b7d0a9e2.jpg 245w," sizes="100vw" width="915" height="494"></figure><h3>Automated identification and relative quantitation with LipidSearch software</h3>LipidSearch software, developed jointly by Professor Ryo Taguchi and MKI, (Tokyo, Japan), is a powerful new tool for automatic identification and relative quantification of cellular lipid molecular species from large amounts of mass spectrometric data obtained in nano-infusion or LC-MS experiments. Using the industry-leading, high-resolution, accurate-mass <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=orbitrap">Thermo Scientific Orbitrap™ technology</a> with exclusive LipidSearch software, the most accurate and confident lipid profiles and identifications can be achieved more quickly than ever before.<ul><li>Compatible with data acquired from Thermo Scientific™ triple quadrupole, ion trap, and Orbitrap mass spectrometers</li><li>Largest lipid database containing &gt;1.5 million lipid ions and their predicted fragment ions</li><li>Identification algorithms for product ion, precursor ion and neutral loss scans</li><li>Alignment of lipid data obtained from multiple LC-MS and MSn experiments</li><li>Relative quantitation of identified lipid precursors in either LC-MS or infusion experiments</li></ul>The database contains defined structures and includes more than 1.5 million lipid ions and their predicted fragment ions. Fragmentation patterns are calculated and improved by using expert knowledge based on experimental results. Lipid adduct ions and MSn fingerprints are also included. Data are stored in XML files and are easily customized.<figure class="image"><img style="aspect-ratio:990/497;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_3_91f1458663.jpg" alt="Thermo Scientific™ LipidSearch™ Software: Lipid fragment ions related to lipid headgroup, fatty acids, and backbone." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_3_91f1458663.jpg 245w," sizes="100vw" width="990" height="497"></figure><h3>LipidSearch software provides an easy-to-use, automated workflow</h3>From peak detection to relative quantitaiton and identification, LipidSearch software provides an easy-to-use, automated workflow.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_4_2043f3d667.jpg" alt="Thermo Scientific™ LipidSearch™ Software: LipidSearch software provides an easy-to-use, automated workflow." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_4_2043f3d667.jpg 245w," sizes="100vw" width="1122" height="530"><h4>Step 1 Data Analysis Module — Peak Detection</h4><ul><li>Raw data file reading</li><li>Smart peak detection</li></ul>The peak detection engine implemented in LipidSearch software can handle different MS experiments and platforms. The combination of unique peak detection algorithms, tailored for each experiment and instrument type, and mass spectral processing functions enables accurate peak detection.LipidSearch software provides two different identification algorithms as well as scoring algorithms:<ul><li>A group-specific algorithm identifies lipids based on the polar head groups or fatty acids using a combination of precursor ion scanning and neutral loss scans from lipids mixtures.</li><li>The comprehensive ID algorithm is used for product ion scans and can discriminate each lipid by matching the predicted fragmentation pattern stored in the database.</li><li>LipidSearch software also provides a set of scoring algorithms to filter out lower probability results</li></ul><h4>Step 2 Identification Module — Lipid Identification</h4><ul><li>Group-specific ID (targeted)</li><li>Comprehensive ID (untargeted)</li><li>Scoring algorithms</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_5_0abd534dd5.jpg" alt="Thermo Scientific™ LipidSearch™ Software: PG 17:0/17:0 Search Results." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_5_0abd534dd5.jpg 245w," sizes="100vw" width="1003" height="456"><h4>Step 3 Quantitation Module — Alignment and Quantitation</h4><ul><li>XIC peak integration</li><li>Retention time alignment</li><li>Relative quantitation</li><li>Statistical analysis</li></ul>Prior to quantitation, lipid results from each sample are aligned within a retention time window. Identified lipids are quantified by detecting their precursor ions from full-scan MS and integrating extracted ion chromatograms.Accurate peak areas are computed by denoising and smoothing the peak profiles prior to separating any partially overlapped peaks. Comparative analysis is then carried out between the multiple sample and control groups using t-test statistics. The mean peak area result for each group is displayed in a “box and whisker” plot.<figure class="image"><img style="aspect-ratio:1129/909;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_6_196073034c.jpg" alt="Thermo Scientific™ LipidSearch™ Software: Alignment results for CoQ7, [M+NH4]+." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_6_196073034c.jpg 194w," sizes="100vw" width="1129" height="909"></figure>Using the industry-leading, high-resolution, accurate-mass <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=orbitrap">Thermo Scientific™ Orbitrap™ technology</a> with exclusive LipidSearch software, achieve the most accurate and confident lipid profiles and identifications more quickly than ever before. For targeted quantitation, LipidSearch software also supports the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=tsq">Thermo Scientific TSQ triple quadrupole MS systems</a>. For both lipidomics workflows, LipidSearch software automatically integrates complex data into a combined report to dramatically reduce data analysis.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_7_f6a5102f0a.jpg" alt="Thermo Scientific™ LipidSearch™ Software." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_7_f6a5102f0a.jpg 245w," sizes="100vw" width="924" height="570"><h5>Minimum/Recommended PC Requirements</h5><ul><li>OS: Microsoft® Windows® 7 Professional (x64) or Windows 8 (x64); English language CPU: Quad - or multi-core CPU, 2 GHz or higher Memory: 8 GB RAM or higher HDD: 50 GB free space for LipidSearch software; 500 GB hard drive SSD (optional): 50 GB free space for LipidSearch software; 256 GB solid-state drive</li></ul>

Thermo Scientific™ ProSightPD Software

Perform comprehensive analysis of top-down proteomics data with Thermo Scientific™ ProSightPD™ software.

<div container-id="cq-colctrl-lt8" comp-id="B1"><div><h3>Confident proteoform identification and characterization</h3></div></div><div container-id="cq-colctrl-lt8" comp-id="B2"><div>Uncover and confidently characterize proteoforms within complex matrices, including proteoforms containing truncations, alternative splices, and post-translationally modified proteins.&nbsp;Extensive searches make use of various fragmentation methodologies (e.g., ETD, HCD, UVPD), allowing you to make full use of the high-quality MS/MS data obtained when searching against the full biological complexity present in UniProt. With Thermo Scientific ProSightPD software, see what is really there and make the most of your data.<div><h3>Key benefits</h3><h5>Sophisticated tools at your fingertips</h5>Utilize several search modes for identifying intact and truncated proteins. ProSightPD software offers the ability to search entire raw files or quickly select specific MS2 scans for further searching. Information in UniProt enables the identification of modified or processed proteins.<h5>Remove the guesswork from database management</h5>Import result files from<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1782"> Proteome Discoverer</a> software or entire proteomes via UniProt formatted XML and FASTA files with Database Manager. Fully customize imported databases using thr ProSight Annotator GUI to characterize PTMs, disulfide bonds, mutations and truncations.<h5>Intuitive user interface</h5>Analyze large datasets with many data files using ProSightPD nodes for <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1782">Proteome Discoverer</a> software. Create multi-step searches and utilize built in results interpretation tools.<h3>Search Types</h3><div>Different database search modes allow you to optimize data interrogation based upon your experimental needs. Searches are driven through the use of a node-based system allowing flexibility of experimental design.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_8a96430534.jpeg" alt="Thermo Scientific™ ProSightPD Software: ProSightPD Database Searching." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_8a96430534.jpeg 245w," sizes="100vw" width="960" height="540"><div>Further information relating to the two search modes, Absolute Mass Search and Biomarker Search.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_2_01f6c31076.jpeg" alt="Thermo Scientific™ ProSightPD Software: Complementary Search Types: Digging Deeper in Complex Samples." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_2_01f6c31076.jpeg 245w," sizes="100vw" width="960" height="540"><h3>Database Management</h3><div>Confident proteoform identification is realized through the use of XML-formatted databases, ensuring that nothing is missed.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_3_db19f0cee9.jpeg" alt="Thermo Scientific™ ProSightPD Software: Database Manager: Add remove isoforms and PTMs." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_3_db19f0cee9.jpeg 245w," sizes="100vw" width="960" height="540"><div>Improvements to data visualization ensure that you can better interact with and interpret your data, minimizing the time taken to deliver actionable results.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_4_575aa9dff5.jpeg" alt="Thermo Scientific™ ProSightPD Software: LFQ Visualizations." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_4_575aa9dff5.jpeg 245w," sizes="100vw" width="960" height="540"><h3>ProSightPD nodes</h3>Top-Down Workflows: ProSightPD&nbsp;includes templates to easily build the most commonly used-top down data analysis workflows.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_5_4f28a7434d.jpg" alt="Thermo Scientific™ ProSightPD Software: ProSightPD 2.0: Tailored Workflows for All Types of Data." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_5_4f28a7434d.jpg 245w," sizes="100vw" width="740" height="400"></div></div></div></div></div></div></div>

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