<p><strong>In this episode of ‪ChromatographyTalk‬, ‪Organomation‬ General Manager David Oliva sits down with Michelle Taylor, Editor-in-Chief of LabCompare, to go behind the scenes of their groundbreaking two-part documentary series on PFAS (per- and polyfluoroalkyl substances).</strong></p><p>The conversation kicks off with a startling revelation: many of the world’s leading PFAS experts have completely stopped eating seafood due to high contamination levels discovered during testing. From there, we dive deep into the technical and regulatory challenges facing today's analytical laboratories.</p><h4><strong>In this episode, we discuss:</strong></h4><ul><li><strong>The Laboratory Throughput Crisis:</strong> Why labs are currently "overwhelmed with samples" and how tiered testing—using single quad instruments for screening before moving to triple quads—is helping to manage capacity without sacrificing sensitivity.</li><li><strong>The Battle Against Background Contamination:</strong> Why PTFE-free (PFAS-free) laboratory equipment is no longer optional when trying to detect "forever chemicals" at the parts-per-trillion and parts-per-quadrillion levels.</li><li><strong>Complex Matrices (Seafood &amp; Packaging): </strong>The technical hurdles of analyzing high-lipid samples like fish and the rising demand for migration testing as states like Rhode Island begin to phase out PFAS in food packaging.</li><li><strong>Global Regulatory Shifts:</strong> A look at the "dual compliance model" required for labs supporting international exporters, especially with the European Union’s stricter enforcement compared to the U.S. monitoring approach.</li><li><strong>The "Grand Challenge" of Unknowns: </strong>How EPA Method 1621 (Total Organic Fluorine) is helping labs close the mass balance gap and why the next generation of bench chemists must embrace *AI and data science* to manage the massive datasets generated by high-resolution mass spectrometry.</li><li><strong>PFAS Destruction vs. Remediation:</strong> &nbsp;The promising (and problematic) methods for breaking the carbon-fluorine bond, and why incineration may inadvertently be spreading shorter-chain PFAS into the air.</li></ul><p>Whether you are a lab manager looking to future-proof your workflow or a chemist navigating the ever-evolving landscape of EPA Method 1633, this episode provides essential insights into the most pressing environmental crisis of our time.</p><h3><strong>Video Transcription</strong></h3><h4><strong>Michelle Taylor: PFAS Testing Is Becoming a Much Bigger Analytical Challenge</strong></h4><p><strong>PFAS analysis has rapidly evolved from a specialized environmental testing problem into a much broader challenge involving drinking water, food, packaging, laboratory contamination, international regulation, data analysis, and even destruction technologies. In an interview with Michelle Taylor, Editor-in-Chief of Labcompare, the discussion explored what laboratories are learning from the latest PFAS research—and why the analytical demands are likely to continue growing.</strong></p><p>Taylor leads editorial content for <strong>Labcompare</strong>, an online resource covering analytical laboratory instrumentation, products, and scientific developments. Among the projects she considers particularly important are two long-form documentaries produced by Labcompare examining per- and polyfluoroalkyl substances (PFAS), first through drinking water and subsequently through food.</p><p>The documentaries brought together subject-matter experts working across PFAS analysis and exposed some of the practical realities laboratories now face: rapidly changing regulations, extremely low detection limits, complex matrices, contamination risks, and sample volumes that can overwhelm laboratory capacity.</p><h4><strong>From drinking water to seafood</strong></h4><p>One of the most memorable findings for Taylor came during production of the second documentary, which focused on PFAS in food.</p><p>Several experts interviewed for the project told her they had stopped eating seafood, in some cases many years earlier, because of concerns surrounding contamination. For Taylor, the consistency and immediacy of those responses illustrated how closely analytical research can intersect with everyday decisions.</p><p>Seafood also demonstrates why PFAS testing can become analytically difficult.</p><p>Fish and other high-lipid samples require effective extraction to release the analytes, followed by rigorous cleanup to remove fats. According to the experts Taylor interviewed, the cleanup step is particularly critical because residual lipids can damage LC columns and create severe matrix interferences.</p><p>Laboratories are therefore using approaches such as enhanced matrix removal and carbon- or silica-based sorbents to reduce the lipid content of extracts before instrumental analysis. The goal is not simply obtaining sufficient recovery, but producing an extract clean enough to maintain analytical performance and laboratory throughput.</p><h4><strong>How laboratories are handling the PFAS sample burden</strong></h4><p>The analytical sensitivity now required for PFAS testing presents another challenge: laboratories may need to measure compounds at <strong>parts-per-trillion levels</strong> while processing growing numbers of samples.</p><p>Automation has therefore become increasingly important, particularly during sample preparation, where repetitive manual procedures can otherwise create a major bottleneck.</p><p>Taylor also described a <strong>tiered analytical strategy</strong> being used by some laboratories. A less demanding measurement can first be used for screening, while samples generating a positive result are subsequently transferred to a more sensitive platform, such as triple-quadrupole mass spectrometry, for confirmation and quantitation.</p><p>This type of workflow can help laboratories concentrate their highest-performance instrumentation on the samples that actually require it rather than applying the most intensive analysis to every incoming sample.</p><p>The broader principle is likely to become increasingly important as PFAS testing expands: laboratories must find ways to increase throughput without sacrificing the sensitivity demanded by regulatory methods.</p><h4><strong>When the laboratory itself becomes a source of PFAS</strong></h4><p>At trace concentrations, contamination introduced during sample preparation or measurement can become comparable to the concentration being determined.</p><p>This makes the materials used throughout the analytical workflow particularly important.</p><p>Taylor emphasized that PFAS laboratories must maintain continuous awareness of potential contamination from <strong>solvents, water, tubing, containers, and other laboratory components</strong>. Equipment containing fluoropolymers such as PTFE may be problematic in certain PFAS workflows because background contamination can contribute to false positives or elevated blanks.</p><p>As detection limits move lower, dedicated PFAS-compatible or fluoropolymer-free laboratory equipment becomes increasingly valuable.</p><p>Taylor described manufacturers offering clearly identified PFAS-free configurations as an important response to this problem. Rather than forcing laboratories to investigate the material composition of each component individually, dedicated configurations can simplify method implementation and reduce uncertainty about potential background sources.</p><p>For laboratories already dealing with demanding workflows and large sample loads, eliminating potential contamination before it occurs can save considerable troubleshooting time.</p><h4><strong>Food packaging could drive the next major wave of testing</strong></h4><p>PFAS concerns are not limited to the food itself.</p><p>The interview also examined <strong>food-contact materials</strong>, including takeout containers and other packaging from which PFAS may migrate into food. State-level restrictions in the United States are already beginning to affect the materials manufacturers can use.</p><p>For contract laboratories, this creates the possibility of another significant increase in demand for compliance and migration testing.</p><p>Taylor’s recommendation is straightforward: laboratories should follow proposed regulations before they become final.</p><p>Waiting until a new requirement takes effect can leave a laboratory simultaneously trying to acquire instrumentation, establish methods, train staff, and respond to customer demand. Monitoring regulatory agencies, scientific meetings, and industry discussions earlier gives laboratories time to prepare analytical capabilities before the testing requirement becomes urgent.</p><p>She expects PFAS restrictions in food packaging to continue developing first through a patchwork of individual state regulations. Once a sufficient number of states adopt restrictions, however, the economics may increasingly encourage suppliers to move toward PFAS-free materials regardless of whether every jurisdiction requires them.</p><p>A national standard could eventually follow that transition.</p><h4><strong>One sample, two regulatory environments</strong></h4><p>International food exporters face another complication: <strong>PFAS requirements are not necessarily the same between the United States and European Union</strong>.</p><p>Taylor noted that laboratories serving both markets may effectively need to operate under a dual-compliance model.</p><p>In the interview, she highlighted EU requirements targeting specific PFAS—including <strong>PFOS, PFOA, PFNA, and PFHxS</strong>—at very low concentrations in certain foods, while the U.S. approach has historically involved a different combination of monitoring programs, evolving compound lists, and import-related requirements.</p><p>For laboratories supporting international customers, this means more than simply selecting a different reporting limit.</p><p>Different markets may require different target lists, methods, documentation, auditing, and compliance procedures. Laboratories therefore need analytical platforms capable of ultratrace measurements while also maintaining the operational flexibility to support multiple regulatory frameworks.</p><p>That additional complexity also carries a practical cost: performing different protocols for different jurisdictions means more staff time, additional workflow management, and potentially greater instrument demand.</p><h4><strong>Total fluorine screening can help laboratories decide what to analyze next</strong></h4><p>Targeted LC-MS/MS methods are highly sensitive, but they only measure compounds included in the analytical panel.</p><p>This creates an important question: <strong>what about fluorinated substances that are present but are not included in the targeted method?</strong></p><p>The interview discussed <strong>EPA Method 1621</strong>, which uses a broader fluorine-based screening approach. Taylor described this type of measurement as useful for helping laboratories assess the gap between compounds captured by targeted LC-MS/MS methods and the broader amount of organofluorine present in a sample.</p><p>Such screening can also become part of a tiered workflow.</p><p>For applications such as food packaging, laboratories could initially use a broader fluorine measurement to determine whether a sample warrants further investigation. Positive or suspicious samples could then move to more selective and sensitive targeted analysis for identification and quantitation.</p><p>Non-targeted high-resolution mass spectrometry can add another layer by revealing compounds outside conventional target lists.</p><p>Together, these approaches create a funnel from broad screening toward increasingly detailed characterization rather than attempting the most comprehensive analysis on every sample from the outset.</p><h4><strong>PFAS analysis is becoming a data problem too</strong></h4><p>High-resolution mass spectrometry can generate enormous datasets containing signals from large numbers of known and unknown compounds.</p><p>As a result, Taylor believes the role of the analytical chemist is changing.</p><p>Strong laboratory skills remain essential, but scientists increasingly need <strong>data literacy</strong> as well. Understanding complex datasets, working with advanced software, and interacting effectively with artificial intelligence and machine-learning tools are becoming important parts of modern analytical work.</p><p>Taylor does not see this change primarily as replacing scientific expertise.</p><p>Instead, she compares it with earlier laboratory automation: repetitive or technically demanding tasks can increasingly be handled by software, allowing scientists to spend more time interpreting results and making decisions.</p><p>AI may also make sophisticated analytical information more accessible. A less experienced mass spectrometry user could potentially receive explanations of complex data through software capable of presenting results in natural language, reducing dependence on a single specialist being immediately available.</p><p>There is another potential advantage beyond speed.</p><p>Machine-learning systems can recognize patterns across large datasets that may be difficult or impossible for an individual scientist to detect manually. As analytical datasets become larger and multidimensional, that pattern-recognition capability could become increasingly valuable.</p><h4><strong>Finding PFAS is only the first half of the problem</strong></h4><p>For years, much of the PFAS discussion has focused on answering two questions:</p><ul><li><strong>Are PFAS present, and how much is there?</strong></li></ul><p>The next challenge is considerably harder: <strong>how do we actually remove or destroy them?</strong></p><p>Taylor described this as an expanding research field that will increasingly involve analytical laboratories.</p><p>The strength of the carbon-fluorine bond makes PFAS destruction difficult. Some treatment approaches seek to break this bond and achieve complete defluorination, but incomplete destruction can create another analytical problem.</p><p>For example, thermal treatment may transform longer-chain PFAS into shorter-chain fluorinated compounds rather than eliminating them completely. Those products may then enter another environmental compartment, including atmospheric emissions.</p><p>Consequently, laboratories studying PFAS destruction must do more than measure disappearance of the original compound. They also need to determine whether <strong>fluorinated transformation products or other byproducts remain</strong>.</p><p>Analytical chemistry therefore has two roles: monitoring PFAS contamination and demonstrating whether remediation technologies truly destroy the substances they are intended to remove.</p><h4><strong>The PFAS problem is expanding beyond water and food</strong></h4><p>The first two Labcompare documentaries focused primarily on <strong>water and food</strong>, two matrices already receiving substantial regulatory and public attention.</p><p>But Taylor does not expect the story to end there.</p><p>If Labcompare produces another PFAS documentary, she sees <strong>PFAS in air</strong> as a likely subject. Discussions with experts during earlier filming repeatedly raised atmospheric contamination, including both direct environmental occurrence and emissions potentially associated with treatment or destruction processes.</p><p>The progression illustrates how quickly the PFAS field is expanding.</p><p>Drinking water regulation accelerated analytical development. Food testing introduced more difficult matrices and new exposure pathways. Packaging is creating another compliance challenge. Environmental remediation raises questions about destruction products. Atmospheric monitoring could become another significant frontier.</p><p>For laboratories already working with chromatography and mass spectrometry, Taylor’s message is essentially to be prepared—even organizations that do not currently consider themselves “PFAS laboratories” may eventually become involved.</p><h4><strong>An analytical field that is still changing rapidly</strong></h4><p>Perhaps the strongest theme running through the interview is that PFAS analysis has no fixed endpoint yet.</p><p>Methods continue to evolve. Regulations change. Target compound lists expand. Instrument sensitivity improves. Laboratories discover new sources of background contamination, while researchers identify additional exposure pathways and investigate new destruction technologies.</p><p>Taylor compares the situation to earlier periods of rapid analytical development, such as the evolution of forensic DNA analysis: each technological advance reveals more information, which in turn creates new questions and new analytical requirements.</p><p>That makes preparation particularly important.</p><p>Laboratories cannot predict every future regulation, but they can follow proposed requirements, develop flexible workflows, invest in contamination control and data capabilities, and understand how their existing chromatography and mass spectrometry expertise could be applied to emerging PFAS challenges.</p><p>The analytical problem is no longer simply detecting a group of “forever chemicals.”</p><p>It is becoming a much larger question of <strong>how we identify them, quantify them, prevent contamination during analysis, understand their movement through food and the environment, comply with evolving regulations, and ultimately prove that they have actually been destroyed.</strong></p><blockquote><p><strong>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</strong></p></blockquote><blockquote><h4><strong>Concentrating on Chromatography Podcast</strong></h4><p>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!</p><p>You can find <strong>Concentrating on Chromatography Podcast </strong>in podcast apps:</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL"><strong>Spotify</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185"><strong>Apple podcast</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography"><strong>podscan</strong></a></li></ul><p>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos"><strong>YouTube channel</strong></a></p></blockquote>

PFAS in Water, Food & Packaging: Michelle Taylor on the "Forever Chemicals" Documentary Series

<p><strong>In the week of September 7, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>6 000 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Thermo Fisher Scientific: Spatial Proteomics for Translational Research</strong></h5><ul><li>Tu, 8.9.2026 07:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6456">Registration</a></li></ul><p>Learn how Thermo Fisher's EVOS S1000 system and Aluora kits reduce sample costs for tumor imaging and support spatial proteomics workflows in translational research.</p><h5><strong>2. Waters Corporation: Streamlining Endotoxin Testing: Automated Sample Preparation and Audit-Ready Workflows for QC Laboratories</strong></h5><ul><li>Tu, 8.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6461">Registration</a></li></ul><p>Learn how combining the Waters Andrew+ Robot and bioMérieux ENDOZYME® II GO automates endotoxin sample preparation and supports efficient, audit-ready QC workflows.</p><h5><strong>3. Thermo Fisher Scientific: Advantages of microbore column use in ion chromatography</strong></h5><ul><li>We, 9.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6480">Registration</a></li></ul><p>Discover how microbore columns can make ion chromatography greener and more cost-effective by reducing eluent consumption and extending consumable lifetime.</p><h5><strong>4. New Food magazine: Measuring what matters: water quality analysis with UV-Visible spectrophotometry</strong></h5><ul><li>We, 9.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6392">Registration</a></li></ul><p>Explore how UV-Visible spectrophotometry supports reliable water quality analysis across a range of laboratory and environmental applications.</p><h5><strong>5. Agilent Technologies: From Complexity to Clarity: A User-Friendly Peptide-Mapping-Based Multi-Attribute Method Workflow to Monitor Critical Quality Attributes for Quality Control</strong></h5><ul><li>We, 9.9.2026 18:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6493">Registration</a></li></ul><p>Learn how a user-friendly peptide-mapping-based multi-attribute method (MAM) workflow simplifies critical quality attribute monitoring and supports routine biopharmaceutical QC.</p><h5><strong>6. US HUPO: Pride, Prejudice, and Plasma - Lessons from History for Modern Proteomics</strong></h5><ul><li>We, 9.9.2026 19:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6482">Registration</a></li></ul><p>Explore how lessons from the history of plasma research can inform modern proteomics, with perspectives on past assumptions, evolving technologies, and future directions.</p><h5><strong>7. Agilent Technologies: Nitrosamine Testing: What Makes the Difference?</strong></h5><ul><li>We, 9.9.2026 19:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6462">Registration</a></li></ul><p>Learn how triple quadrupole LC/MS and appropriate column selection enable sensitive nitrosamine and NDSRI testing in pharmaceuticals at ultra-trace levels.</p><h5><strong>8. Waters Corporation: GLP-1 Analogs: Enhancing Impurity Profiling with LC-UV/MS Workflows</strong></h5><ul><li>Th, 10.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6467">Registration</a></li></ul><p>Learn how LC-UV/MS and HRMS workflows support GLP-1 therapeutic impurity profiling, including identification of sequence variants and degradation pathways.</p><h5><strong>9. Technology Networks: Tackling Bispecific Antibody Purification: A Polishing Case Study</strong></h5><ul><li>Th, 10.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6468">Registration</a></li></ul><p>Explore resin screening strategies for bispecific antibody polishing to remove product-related impurities and support efficient process scale-up.</p><h5><strong>10. KNAUER: Autonomous Impinging Jets Mixing for LNP Process Development</strong></h5><ul><li>Th, 10.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6464">Registration</a></li></ul><p>Learn how automated impinging jets mixing, inline analytics, and closed-loop optimization can accelerate LNP process development for RNA delivery research.</p><h5><strong>11. SciY/Mestrelab Research: Advancing Lean Chemometrics: Iterative Optimization Technology as a Process Analytical Technology Tool for Reducing Calibration Burden</strong></h5><ul><li>Th, 10.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6428">Registration</a></li></ul><p>Discover how Iterative Optimization Technology and lean chemometrics can accelerate PAT deployment while reducing calibration burden in analytical workflows.</p><h5><strong>12. Technology Networks: Improving mAb Purification Efficiency With Hydrophobic Interaction Chromatography</strong></h5><ul><li>Th, 10.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6377">Registration</a></li></ul><p>Learn how flow-through hydrophobic interaction chromatography can improve monoclonal antibody purification by replacing traditional CEX polishing, increasing loading capacity, and supporting process scale-up.</p><h5><strong>13. SCIEX: LC-MS/MS Analysis of Nitrosamines using novus V55</strong></h5><ul><li>Fr, 11.9.2026 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6485">Registration</a></li></ul><p>Discover sensitive LC-MS/MS workflows for ultra-trace nitrosamine analysis using the SCIEX novus V55, including sample preparation, MRM quantitation, validation, and regulatory compliance.</p><h5><strong>14. SelectScience: GLP-1 &amp; GIP under the lens: HRMS strategies for synthetic peptide profiling</strong></h5><ul><li>Fr, 11.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6484">Registration</a></li></ul><p>Discover how HRMS workflows support confident sequence confirmation, impurity profiling, and degradation analysis of synthetic peptides such as semaglutide and tirzepatide.</p>

Webinars LabRulezLCMS Week 37/2026

Coupling micro-flow liquid chromatography with Q-Orbitrap high-resolution mass spectrometry for greener, comprehensive pesticide residue analysis in fruits and vegetables

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Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

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Waters Empower Chromatography Data System (CDS)

Empower Chromatography Data System (CDS) has been intentionally designed to help you address your most rigorous chromatographic, regulatory, and networking challenges.

<div><div id="title-230ef9ecce" data-locator="title-with-text"><h3><strong>Elevate your chromatography with the universal language of the lab</strong></h3></div></div><div><div id="text-3b75bcd8fb" data-locator="text"><p><strong>Simplifying the way you collect, manage, and report chromatography test results is critical to your lab efficiency. With a suite of flexible functionalities that grows to meet your changing quality, business, and laboratory needs, Empower Chromatography Data System (CDS) has been intentionally designed to help you address your most rigorous chromatographic, regulatory, and networking challenges.</strong></p><p>Empower CDS<strong> </strong>helps your entire laboratory operate more efficiently and securely with the industry's most advanced data acquisition, management, processing, analytics, and reporting capabilities. Easily scalable from a single workstation to an enterprise-wide network, where you can work at the bench, across sites, and even remotely with on-premises or cloud options, Empower CDS provides an environment where your records are traceable, so you always have full control of your most critical asset - your data.</p><div><div id="text-8f4122209c" data-locator="text"><h3><strong>Overview</strong></h3><div data-locator="section-container-body"><div><div><div data-locator="layoutcontainer-"><div><div id="text-07744ba23e" data-locator="text"><ul><li><strong>Store and retrieve chromatography data using an embedded, relational database</strong>; simplifying data retrieval by searching with criteria that is meaningful to you</li><li><strong>Save time, reduce manual integration, and calculate more precise peak integrations</strong> with the ApexTrack algorithm in Empower CDS</li><li><strong>Easily control</strong> Waters high-performance liquid chromatography (HPLC), UHPLC, and UPLC systems, as well as non-Waters HPLC, gas chromatography (GC), photodiode array detector (PDA), and mass spectrometry (MS) systems</li><li><strong>Achieve more enhanced detection capabilities</strong> when using Waters mass detectors or the Waters ACQUITY UPLC PDA Detector</li><li><strong>Grow seamlessly from a single workstation to an enterprise-wide system</strong> with the scalable, modular architecture in Empower CDS, which fits into the most modern and secure high-availability corporate architecture</li><li><strong>Deploy applications</strong> such as dissolution, method validation, integrated chemical structures, and polymer or size exclusion analysis</li></ul></div></div><div><div id="text-a7790dd22b" data-locator="text"><h3><strong>Recommended Use</strong></h3><p>For advanced data acquisition, management, processing, reporting, and distribution of chromatography analysis data.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Empower_Chromatography_Data_System_CDS_Operate_more_efficiently_and_securely_with_the_flexible_capabilities_of_Empower_Chromatography_Data_System_CDS_9625ca12d5.jpg" alt="Waters Empower Chromatography Data System (CDS): Operate more efficiently and securely with the flexible capabilities of Empower Chromatography Data System (CDS)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Empower_Chromatography_Data_System_CDS_Operate_more_efficiently_and_securely_with_the_flexible_capabilities_of_Empower_Chromatography_Data_System_CDS_9625ca12d5.jpg 234w," sizes="100vw" width="1024" height="682"></p><div><div id="text-f39d8a00c0" data-locator="text"><h3 data-locator="modal-title"><strong>Interface options unique to your users</strong></h3><p>Empower Software represents a fundamental shift in <strong>UPLC/UHPLC, HPLC, and LC-MS</strong> system usability. It is equipped with unique interface options designed for your lab, regardless of the task or user's skill level. When users log in, they are presented with the application that provides the appropriate workflow for them. If authorized, users can select another software interface that is suitable for their current task.</p><h5><strong>The three Empower Software applications are:</strong></h5><ul><li><strong>QuickStart</strong>&nbsp;- Collect, process, and report data from a single-window access. Use a wizard to set up methods and run assays. Navigate the entire Empower environment from one screen, including instrument control, view plotted data in real time, view raw data, and access tools to customize and print reports.</li><li><strong>Pro</strong>&nbsp;- Access to all software functions for advanced users, system administrators, or anyone who needs total control.</li><li><strong>Open Access</strong>&nbsp;- Select your method and the number of samples you need to run and get started with the click of a mouse. No chromatography experience is necessary.</li></ul><figure class="image"><img style="aspect-ratio:1024/594;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Empower_Chromatography_Data_System_CDS_The_Empower_Quick_Start_interface_uses_a_navigation_bar_to_guide_you_through_the_software_and_all_tasks_are_carried_out_in_one_window_dfe3ec8bb7.jpg" alt="Waters Empower Chromatography Data System (CDS): The Empower QuickStart interface uses a navigation bar to guide you through the software and all tasks are carried out in one window." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Empower_Chromatography_Data_System_CDS_The_Empower_Quick_Start_interface_uses_a_navigation_bar_to_guide_you_through_the_software_and_all_tasks_are_carried_out_in_one_window_dfe3ec8bb7.jpg 245w," sizes="100vw" width="1024" height="594"></figure><div><div id="text-b65d021cbc" data-locator="text"><h3 data-locator="modal-title"><strong>Ideal for data analysis</strong></h3><h5><strong>Improve data analysis workflows and information sharing across your lab with Empower Software, which helps you achieve:</strong></h5><ul><li><strong>Reliable shoulder peak detection</strong> - ApexTrack effectively detects and integrates shouldered peaks, providing more reliable detection of low-level peaks on noisy or sloping baselines for less manual manipulation and more accurate results.</li><li><strong>Automated custom calculations</strong> - Simply use a wizard to set up your parameters, like averages or % relative standard deviation (RSD). After configuring the calculation once, Empower Software automatically determines the answer when data is processed - no more data transfer, spreadsheet manipulation, or transfer errors.&nbsp;</li><li><strong>Better information sharing </strong>- Easily share information with colleagues worldwide with results and reports stored within the same database. Create combined summary reports across laboratories, instruments, and projects, regardless of where data was acquired or processed. Create PDFs or email reports, distribute methods and information electronically, access information between remote sites, and review and electronically sign off results.</li><li><strong>Fast access to information </strong>- Empower CDS has an embedded relational database, enabling you to store chromatographic results, automatically linking all metadata without manual information tracking or documentation, and better preparing you for review questions or audits. Find data fast and easily with relevant search terms and automatic time stamps of user activity - without a flat file environment, awkward naming conventions, or manual method and result versioning.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Empower_Chromatography_Data_System_CDS_9a791332d9.jpg" alt="Waters Empower Chromatography Data System (CDS): As an example of the breadth of technology that Empower offers, the software can control mass spectrometry (MS) instruments and acquire and process MS data. Spectral information from multiple detection modes can be viewed simultaneously. This enables scientists to easily perform complex analyses with minimal training, increasing lab productivity." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Empower_Chromatography_Data_System_CDS_9a791332d9.jpg 245w," sizes="100vw" width="1024" height="553"></p><div><div id="text-a10f03a0ca" data-locator="text"><h3 data-locator="modal-title"><strong>At-a-glance key chromatography data views to maximize lab resources</strong></h3><p>Empower Laboratory Analytics assembles and displays critical chromatography performance data in easy-to-view, graphical dashboards so you can focus on what’s most important―the interpretation of key information, not its collection.&nbsp;</p><p>Empower Laboratory Analytics offers a range of prebuilt dashboard types, including system summary, system usage, project usage analysis, and methods analysis. These at-a-glance dashboards let you quickly and accurately determine how laboratory resources are being used, without significant manual effort. With these dashboards, you can make evidence-based decisions on which improvements are needed to increase laboratory efficiency.&nbsp;</p><p>With Empower Laboratory Analytics, you can maximize system utilization and better manage resources. You can quickly identify training needs, error messages affecting workflows, and non-robust processing methods. With Empower Software, your lab can better plan for capital expenditures and identify opportunities to shorten run times with UPLC/UHPLC technology.</p></div></div><div><div id="text-497ef11ba3" data-locator="text"><h3 data-locator="modal-title"><strong>Monitor your chromatography system anytime, anywhere</strong></h3><h5><strong>Empower Mobile gives you wireless access to Empower Software from a tablet or smartphone, making it easier to know what’s happening in your laboratory no matter where you are to:</strong></h5><ul><li>Improve laboratory efficiency</li><li>Easily find and share results remotely</li><li>Expedite workflow for signoff on reports</li><li>Lower operating costs for system administration tasks</li><li>Reduce sample and mobile phase waste</li></ul><p>Whether you are an analyst, manager, or system administrator, this easy-to-use application, specially designed to run on mobile devices, gives you the flexibility to work on other priorities, knowing that you can use your mobile device at any time to monitor system status, perform routine system administration tasks, and review and sign off reports.</p><p>Empower Mobile is versatile and has been optimized to work with Apple iPad and iPhone and Android tablet and smartphone devices. Empower Mobile can be installed on your Empower Software network in either workgroup or enterprise configurations, all at no additional cost to you.&nbsp;</p><div><div id="text-8f9e5e7bd5" data-locator="text"><blockquote><h3><strong>Empower 3.9.0 is here</strong></h3><h5><strong>Keep your lab current with the latest Empower Software release built to enhance efficiency, productivity, and compliance readiness so you can drive better scientific and business outcomes across your organization.</strong></h5><h4><strong>With Empower 3.9.0 you can:</strong></h4><ul><li><strong>Reduce risk: </strong>Full Windows® 11 support to keep your data safe with the latest Microsoft® updates.</li><li><strong>Increase efficiency: </strong>Updates in the Review window simplify work for users when workflows require technical controls to reduce the potential for human bias.</li><li><strong>Reduce cost and effort: </strong>New Empower RapidDeploy Software option for LAC/E devices reduces the effort spent planning, preparing, and coordinating LAC/E device upgrades and significantly reduces resource constraints often encountered during upgrades — reducing upgrade costs and minimizing downtime during upgrades so you can&nbsp;keep your operations current.</li></ul><h4><a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/nextgen/us/en/services/software-services/software-upgrades/empower-software-upgrade-request.html"><strong>Upgrade to the latest version!</strong></a></h4></blockquote></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>

Waters MassLynx Mass Spectrometry Software

With development largely driven by input from our extensive user base, MassLynx provides the fundamental platform to acquire, analyze, manage, and share mass spectrometry information.

<h3><strong>Our well-established MassLynx software package delivers market-leading versatility and flexibility for all application areas.</strong>&nbsp;</h3><div><div id="text-f93532e53f" data-locator="text"><p><strong>MassLynx was first pioneered to simplify interaction with mass spectrometry (MS) and has continually improved to meet changing customer needs. The result: a market-leading software solution that allows users to best leverage their MS system and harness real-time intelligence, ensure MS system performance, and more quickly convert sample data into valuable knowledge. With development largely driven by input from our extensive user base, MassLynx provides the fundamental platform to acquire, analyze, manage, and share mass spectrometry information.</strong></p><p>MassLynx Software features a <strong>21 CFR Part 11-compatible security</strong> including <strong>file encryption, audit log</strong>, and <strong>secure archival/retrieval technology</strong> with flexible security policies to meet your lab requirements. Waters also offers excellent <a target="_blank" rel="noopener noreferrer" href="https://www.waters.com/waters/nav.htm?cid=1000349" data-di-id="di-id-5aca7e0f-b105e917"><strong>service and suppor</strong>t</a> to get the system up and running – for on-time results without the stress.</p><h2><strong>MassLynx Quantitation Applications</strong></h2><div><div id="title-eb2a5ffa29" data-locator="title-with-text"><h4><strong>Streamline quantitative data acquisition and processing</strong></h4></div></div><div><div id="text-baefaeaec6" data-locator="text"><p>The rate determining step in many analyses is not data acquisition, but the speed your data can be converted into useful information.</p><p>To assist you with both application-specific data acquisition and the transformation of data into usable results, MassLynx for quantitation offers a range of <strong>application managers</strong> with specialized data processing functionalities, which eliminates the need for complex time-consuming manual data review, increasing your productivity.</p><p>The functionality of <strong>MassLynx application managers</strong> has been guided by our customers and optimized for your data analysis and processing requirements.&nbsp;</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Mass_Lynx_Quantitation_Applications_b5a284165b.jpg" alt="Waters: MassLynx Quantitation Applications." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Mass_Lynx_Quantitation_Applications_b5a284165b.jpg 245w," sizes="100vw" width="1428" height="625"></p><h3><strong>Overview</strong></h3><div data-locator="section-container-body"><div><div><div data-locator="layoutcontainer-"><div><div id="text-4b29255c4a" data-locator="text"><ul><li>A tried and well-established software package, MassLynx delivers the versatility and flexibility you require for all of your quantitation applications</li><li>MassLynx security system provides compliance ready tools to meet GxP and 21 CFR Part 11 regulations and TargetLynx XS delivers the information necessary for regulatory compliance</li><li>Inlet method editor and MS method editor allow the user to intuitively build LC-MS/MS methods for quantitative data acquisition</li><li>Auto-dwell for MRM dwell times makes it easy to optimize MRM methods to maximize points per peak and get the best quantitative performance</li><li>IntelliStart guarantees maximum system performance and usability for reproducible results</li></ul></div></div><div><div id="text-adc477d45b" data-locator="text"><h3><strong>Recommended Use</strong></h3><p>MassLynx quantitation applications streamline quantitative data acquisition and processing.</p><div><div id="title-be02784995" data-locator="title-with-text"><h2><strong>MassLynx Mass Detection Applications</strong></h2></div></div><div><div id="title-d5b484d548" data-locator="title-with-text"><h4><strong>Intuitively interact with your mass detection system with MassLynx</strong></h4></div></div><div><div id="text-0fc50dc8ea" data-locator="text"><p>The challenges of mass spectrometry (MS) analyses are often compounded by the use of several types of analytical instruments and high personnel turnover. To maintain and even increase laboratory productivity and efficiency, MassLynx Software simplifies interaction with your mass detection system. MassLynx enables users with a wide range of expertise to easily acquire high-quality mass spectral data with minimal training.</p><p>MassLynx application managers enable you to focus the power of MS on your laboratory's tasks.</p><h3><strong>Overview</strong></h3><div data-locator="section-container-body"><div><div><div data-locator="layoutcontainer-"><div><div id="text-fb3c291dd5" data-locator="text"><ul><li>MassLynx delivers the versatility and flexibility you require for all of your mass detection applications</li><li>Easy-to-use application managers enable you to simply transform mass spectral data into usable results</li><li>Intuitive setup and interaction with the mass detector guarantees optimal performance and reproducible results</li><li>Routinely using the same intuitive software provides familiarity and simplicity for more efficient workflows</li><li>Inlet method editor and MS method editor allow the user to intuitively build LC-MS methods for qualitative and quantitative data acquisition</li></ul></div></div><div><div id="text-4b89cfd965" data-locator="text"><h3><strong>Recommended Use</strong></h3><p>Masslynx Application Managers enable laboratories to confidently produce high quality results without complexity.</p><p><img style="aspect-ratio:1086/319;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Mass_Lynx_Mass_Detection_Applications_f261c2afd6.jpg" alt="Waters: MassLynx Mass Detection Applications." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Mass_Lynx_Mass_Detection_Applications_f261c2afd6.jpg 245w," sizes="100vw" width="1086" height="319"></p><div><div id="title-67851c4cd4" data-locator="title-with-text"><h2><strong>MassLynx High-Resolution Applications&nbsp;</strong></h2></div></div><div><div id="title-1688118c0d" data-locator="title-with-text"><h4><strong>Fully characterize your samples with Waters high-resolution mass spectrometry</strong></h4></div></div><div><div id="text-fc7cb897e2" data-locator="text"><p>As the power of high-resolution mass spectrometry (HRMS) allows today’s labs to obtain high quality data, the challenge is then to confidently identify and characterize components of interest.</p><p>Waters MassLynx Applications enable your lab to efficiently process and interpret HRMS data sets – whether your samples are biological, chemical, environmental, or pharmaceutical, we have a solution that meet your needs, whether it's based on gas chromatography (GC-MS) or liquid chromatography mass spectrometry (LC-MS).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Mass_Lynx_High_Resolution_Applications_9811f2e6b9.jpg" alt="Waters: MassLynx High-Resolution Applications." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Mass_Lynx_High_Resolution_Applications_9811f2e6b9.jpg 245w," sizes="100vw" width="1422" height="594"></p><h3><strong>Overview</strong></h3><div data-locator="section-container-body"><div><div><div data-locator="layoutcontainer-"><div><div id="text-b16ee61766" data-locator="text"><ul><li>Rapidly identify metabolites with MetaboLynx XS</li><li>Achieve confident structural elucidation with MassFragment</li><li>Automate the processing of LC-MS, GC-MS, LC-MS/MS, or GC-MS/MS data with ChromaLynx</li><li>Meet quantitative and qualitative proteomics research requirements with ProteinLynx Global Server (PLGS)</li></ul></div></div><div><div id="text-1dee9a4274" data-locator="text"><h3><strong>Recommended Use&nbsp;</strong></h3><p>For identifying and characterizing data acquired using high-resolution mass spectrometry.</p></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>

Products from category Chromatography software - page 1

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