A clear guide to Normal Phase SPE: when to use it, how polar interactions drive retention, and which solvents to choose in increasing polarity—plus a quick reference list for optimized sample preparation.

This week we bring you application notes by Agilent Technologies, Shimadzu and Waters Corporation and poster by Thermo Fisher Scientific / HPLC!

Fresh updates for ISC 2026 are live! Registration and abstract submission open 15 January. Check new fees, program highlights, invited speakers, short courses, and opportunities for young scientists.

Learn how to manually build a calibration curve in Clarity using previously measured standards. A step-by-step guide covers adding peaks, assigning compounds, entering levels, and verifying calculated results.

SGS and Thermo Fisher present a high-resolution LC-HRAM-MS method for sensitive targeted and non-targeted PFAS screening in pharmaceutical materials.

A fast HPLC-UV method was optimized to quantify trigonelline, 5-CQA, and caffeine in multiple Arabica cultivars. The method proved robust and highlighted major cultivar and roasting-related changes.

12 webinars: Andrew+ Robot, Chromeleon, DLS, field flow fractionation, GLP-1 analysis, green chemistry RNA, IRMS, Karl Fischer, lipidomics, metabolomics, nanocarriers, oligonucleotides, PFAS, proteomics, SEC

Industrial PhD student Mark develops a transferable UPLC–MS method for phospholipid analysis in total parenteral nutrition, linking cutting-edge lipidomics with real-world pharmaceutical QC and patient care.

RECETOX researchers showed that some flame retardants in car interiors rise up to 700× in summer compared to winter, revealing strong temperature-driven exposure risks for drivers and passengers.

Dr. Petr Cígler receives the Rudolf Lukeš Prize 2025 for groundbreaking lipid and diamond nanoparticles that advance gene therapy, cancer treatment, imaging, and modern vaccine development.