This week we bring you application notes by Agilent Technologies, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!

A streamlined workflow for N-linked glycan sample preparation, combining PNGase F digestion, fluorescent labeling, and HILIC SPE clean-up for reliable HPLC and LC-MS analysis.

Learn how shutdown methods in Clarity Sequence Options enable automatic post-sequence actions such as cooling devices, switching off lamps, or sending shutdown commands after the last run.

Sheffield researchers validated Thermo Scientific Tox Explorer for LC-MS/MS drug screening in post-mortem vitreous humor, confirming its sensitivity, stability and forensic value.

LC-HRMS screening combined with temporal clustering identified daily domestic discharge patterns in wastewater, enabling improved interpretation of population chemical exposure.

A novel persistence-directed testing approach combined with nontarget GC-MS and LC-HRMS revealed a significant fraction of persistent chemicals in offshore oil platform produced waters.

7 webinars: automated liquid handling, discovery chemistry, GLP-1, HPLC maintenance, LC workflows, SCIEX OS software, SFE/SFC, UV-Vis, workflow automation

Graduate researcher Schyler Odum discusses UPLC-MS workflows, challenges in antibiotic discovery, and why stronger support for developing new antimicrobials is urgently needed.

Many labs report downtime, high service costs, and support gaps with nitrogen generators. Organomation offers a more reliable alternative with strong customer service and long-lasting NITRO-GEN+ systems.

Matrix effects can suppress or enhance analyte signals and compromise accuracy. Learn how sample prep techniques—especially SPE with Strata-X PRO—reduce phospholipid interference and improve LC-MS results.