<p><strong>Microplastics have emerged as one of the most widely discussed environmental contaminants of our time. Regardless of where we live, daily exposure to microplastics has become virtually unavoidable—these tiny plastic particles are present in the air we breathe, the water we drink, and the environments we inhabit. As researchers work to better understand the sources, transport pathways, and impacts of microplastics, the demand for reliable microplastic analysis methods continues to grow.</strong></p><p>While techniques such as FTIR and Raman spectroscopy have become standard tools for identifying microplastics, their utility is limited for smaller particles (i.e. nanoplastics) and in complex matrices. More advanced microplastic analysis methods can provide a deeper understanding of what these particles contain and how they may change over time in the environment.</p><div><h3><strong>The Limits of Spectroscopic Microplastic Analysis Methods</strong></h3><p><strong>Fourier-Transform Infrared</strong> (<strong>FTIR</strong>) and <strong>Raman spectroscopy </strong>are widely used microplastic analysis methods because they can<strong> identify polymer types</strong> by measuring how electromagnetic radiation interacts with a material. These techniques are valuable for determining whether a particle is polyethylene, polypropylene, polystyrene, or another common plastic. For many studies, this information is sufficient to confirm the presence of microplastics, especially in clean samples with sufficient microplastic density.</p><p>However, <a target="_blank" rel="noopener noreferrer" href="https://www.leco.com/application/environmental/"><strong>environmental samples</strong></a> are rarely clean and compositionally simple. Microplastic particles can become weathered and obscured by other materials in the environment, making their accurate identification with spectroscopy difficult. Additionally, if researchers want to understand what additives, degradation products, or pollutants are associated with the plastic, particle identification alone is not enough. Thus, FTIR and Raman spectroscopy methods alone struggle to thoroughly characterize these complex chemical components, particularly in challenging environmental matrices. As questions surrounding microplastic exposure become increasingly important, researchers require analytical techniques capable of examining the chemistry of a sample in greater detail, not simply confirming the presence of the physical particle itself.</p></div><div><h3><strong>Thermal Desorption and Pyrolysis GCxGC-TOFMS For Deeper Microplastic Analysis</strong></h3><p><strong>Thermal Desorption</strong> (<strong>TD</strong>) and <strong>Pyrolysis </strong>(<strong>Py</strong>) coupled with comprehensive two-dimensional gas chromatography and time-of-flight mass spectrometry (<a target="_blank" rel="noopener noreferrer" href="https://www.leco.com/core-analysis/gc-and-gc-ms/"><strong>GCxGC-TOFMS</strong></a>) offer a powerful alternative for investigating nano- and microplastics in complex samples. These techniques provide complementary information about sample composition.&nbsp;</p><p><strong>Thermal desorption</strong> releases volatile and adsorbed compounds, including environmental contaminants, degradation products, and VOCs associated with microplastic particles. This can reveal important information about chemicals present within or on the plastic.</p><p><strong>Pyrolysis </strong>thermally deconstructs the polymeric material, breaking it into GC-amenable characteristic degradation compounds. These compounds act as chemical markers that can be used to identify the various polymers present. When analyzing complex or heavily weathered microplastics that may be difficult to characterize using traditional spectroscopic techniques, pyrolysis is particularly advantageous.</p><p>The most significant benefit comes from pairing these techniques with comprehensive <strong>two-dimensional gas chromatography</strong>. Environmental samples often contain hundreds or even thousands of compounds that coelute in 1D GC-MS, making it difficult or impossible to identify each compound. GCxGC provides significantly greater separation capability, helping analysts distinguish important polymer markers from background matrix components. This enhanced separation improves the mass spectrometer’s ability to identify characteristic polymer pyrolysis products, even in highly complex environmental samples. As a result, researchers can detect and identify challenging microplastics without the extensive purification steps often required by other analytical workflows.</p><p>Another unique advantage of this approach is that thermal desorption and pyrolysis can be used in series on the same sample. Together, they create a more complete chemical profile of the sample.</p></div><div><h3><strong>A Powerful Microplastics Analysis Workflow for Deeper Insight into the Effects on Our Environment</strong></h3><p>FTIR and Raman spectroscopy remain valuable tools for rapid screening and flagging samples containing microplastic particles. However, by<strong> combining thermal desorption, pyrolysis, and GCxGC-TOFMS</strong>, analysts can obtain a <strong>much more comprehensive view of plastic</strong>s in their samples and their environmental implications. As environmental research continues to advance and concerns surrounding microplastic contamination grow, researchers will increasingly require information that extends beyond answering the question,&nbsp;<i>“What plastic is present?”&nbsp;</i>&nbsp;</p><p>Ultimately, this deeper level of characterization can provide new insights into the environmental fate of microplastics and help scientists better understand their potential impacts on ecosystems and human exposure.</p></div>

Surpassing the Limits of Traditional Microplastic Analysis Methods with Thermal Desorption and Pyrolysis GCxGC-TOFMS

Oligonucleotide and mRNA Analysis Resource Roundup

<p><strong>NIST26 introduces integrated chromatogram processing, deconvolution, and library searching for EI GC-MS and LC-MS/MS data, but the workflow begins with one essential requirement: chromatographic data must be available in the mzML format. In his presentation </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/Conversion_to_mz_ML_63e134bb34.pdf"><i><strong>Conversion to mzML Format for NIST26 Chromatogram Processing</strong></i></a><strong>, James Little of Mass Spec Interpretation Services explains how vendor data can be converted to mzML using either instrument-vendor software or the freely available MSConvert tool from ProteoWizard, and highlights several settings that are critical for successful processing in NIST26.</strong></p><h4><span><strong>NIST26 Chromatogram processing requires mzML</strong></span></h4><p>For the chromatogram-processing workflow described in the presentation, <strong>mzML is the accepted input format</strong>. Proprietary LC-MS or GC-MS data therefore need to be converted before they can be loaded into the NIST26 chromatogram-processing environment.</p><p>There are two principal ways to obtain an mzML file:</p><ul><li>conversion using software supplied by the instrument manufacturer,</li><li>conversion using <strong>MSConvert</strong>, which is included in the free <strong>ProteoWizard</strong> software package.</li></ul><p>Using an open format such as mzML also provides a practical way to move mass spectrometry data between different software environments without relying exclusively on proprietary vendor formats.</p><h4><span><strong>Using ProteoWizard and MSConvert</strong></span></h4><p>MSConvert is installed as part of the complete ProteoWizard package rather than as a separate application. After installing ProteoWizard, users can access either the graphical MSConvert interface or the command-line version.</p><p>The presentation recommends the stable release for routine work, while noting that newer or nightly builds may sometimes provide improved support for recently introduced vendor formats or additional control over data-processing filters. This can be particularly relevant when handling vendor files in which centroiding behavior or peak picking requires closer attention.</p><p>For most users, the graphical interface provides a straightforward route from proprietary raw data to an mzML file suitable for further NIST26 processing.</p><h4><span><strong>Start by selecting mzML as the output format</strong></span></h4><p>The first step in MSConvert is to select the source file or dataset using the <strong>Browse</strong> function.</p><p>The software supports a broad range of mass spectrometry data formats, and the file-selection window can either be restricted to a particular vendor format or set to display any supported spectral format.</p><p>After selecting the source data, the output format must be set to <strong>mzML</strong>. The screenshots in the presentation show this setting directly in the MSConvert options panel before the conversion is started.</p><p>The user can also select the destination folder and other file-output options before adding the selected dataset to the conversion queue.</p><h4><span><strong>Add the data and start the conversion</strong></span></h4><p>Once the source file and output settings have been selected, the file is added to the conversion list using the <strong>Add</strong> command.</p><p>The conversion itself is then launched with <strong>Start</strong>.</p><p>For simple datasets that are already stored in the correct spectral representation, this may be all that is required. However, James Little emphasizes an additional requirement that is particularly important for NIST26: the data must be <strong>centroided</strong>.</p><h4><span><strong>Centroided data are required</strong></span></h4><p>According to the presentation, <strong>profile-mode data are not acceptable for this NIST26 chromatogram-processing workflow</strong>. The spectra must instead be in centroided, or peak-picked, form.</p><p>Profile spectra contain the full measured shape of each mass spectral signal across the m/z axis. Centroided data reduce these profiles to discrete peaks represented by their characteristic m/z and intensity values.</p><p>If the original vendor data are still in profile mode, centroiding can be performed during conversion by adding the <strong>Peak Picking</strong> filter in MSConvert.</p><p>This means that the conversion step can perform two operations at once:</p><p><strong>vendor raw data → centroiding / peak picking → mzML</strong></p><p>The resulting mzML file can then be used as input for NIST26 chromatogram processing.</p><h4><span><strong>Peak Picking must be the first filter</strong></span></h4><p>One of the most important practical details in the presentation is the position of the Peak Picking operation in the MSConvert filter sequence.</p><p>If centroiding is required, <strong>Peak Picking must be the first algorithm or filter in the list</strong>. Placing another processing function before it can interfere with the intended conversion workflow.</p><p>MSConvert allows the user to select the Peak Picking filter, define the relevant MS levels, and add it to the processing sequence before starting conversion. The example shown in the presentation applies vendor-based peak picking to selected MS levels.</p><p>If there is uncertainty about whether the source data are already centroided, the Peak Picking filter can still be included. According to the presentation, applying it to data that are already centroided does not alter the file unnecessarily.</p><p>This provides a useful safeguard when the acquisition mode of an older dataset is uncertain.</p><h4><span><strong>Selecting the appropriate MS levels</strong></span></h4><p>Peak picking does not necessarily have to be applied identically to every spectrum in a dataset. MSConvert allows users to specify the <strong>MS levels</strong> to which the filter should be applied.</p><p>This is especially relevant for LC-MS/MS data, where a file can contain both precursor-level MS spectra and tandem MS spectra.</p><p>The conversion settings should therefore reflect the way the original data were acquired and how those data will subsequently be processed in NIST26.</p><h4><span><strong>Be aware of changes in file size</strong></span></h4><p>The presentation also notes that converted files may become substantially different in size from the original vendor files.</p><p>This is worth considering when working with large LC-MS/MS datasets or processing batches of chromatograms. The size of the resulting mzML file can depend on the original acquisition mode, centroiding, compression settings, the number of MS levels, and other output parameters.</p><p>Storage requirements should therefore be considered before converting large collections of raw data.</p><h4><span><strong>A simple workflow for preparing data for NIST26</strong></span></h4><p>The overall procedure presented by James Little can be summarized as a short sequence:</p><ol><li>Obtain the original vendor LC-MS or GC-MS data.</li><li>Open the data in MSConvert or use the vendor's own conversion software.</li><li>Select <strong>mzML</strong> as the output format.</li><li>Check whether the spectra are centroided.</li><li>If necessary, add <strong>Peak Picking</strong> as the first processing filter.</li><li>Select the appropriate MS levels.</li><li>Add the file to the conversion list.</li><li>Start the conversion.</li><li>Use the resulting mzML file for NIST26 chromatogram processing.</li></ol><p>The procedure itself is straightforward, but the centroiding requirement is important. A file can have the correct <code>.mzML</code> extension and still be unsuitable for the workflow if its spectra remain in profile mode.</p><h4><span><strong>From vendor data to integrated NIST26 processing</strong></span></h4><p>File conversion may appear to be a relatively minor step compared with deconvolution, spectral interpretation, and library searching, but it establishes the foundation for the entire downstream workflow.</p><p>By using mzML as the common input format, NIST26 can process data originating from different instrument platforms through a more consistent workflow. ProteoWizard and MSConvert provide a practical bridge between proprietary mass spectrometry files and this standardized format.</p><p>The key message from the presentation is therefore simple: <strong>convert to mzML, ensure the spectra are centroided, and place Peak Picking first whenever centroiding is required</strong>. Once those conditions are met, the data are ready for the integrated chromatogram-processing and library-searching capabilities available in NIST26.</p>

Conversion to mzML Format for NIST26 Chromatogram Processing

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In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

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My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.

James Little/Mass Spec Interpretation Services

Phenomenex Strata SAX Solid Phase Extraction (SPE)

The quaternary amine group on this sorbent remains positively charged under all conditions, giving a strong anion-exchange mechanism of retention.

<p><strong>Ion-Exchange Solid Phase Extraction Sorbent (SPE)</strong></p><p>The quaternary amine group on this sorbent remains positively charged under all conditions, giving a strong anion-exchange mechanism of retention.</p><figure class="image"><img style="aspect-ratio:500/150;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_sax_470d923b27.webp" alt="Phenomenex: Strata-SAX" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_sax_470d923b27.webp 245w," sizes="100vw" width="500" height="150"></figure><ul><li><strong>Surface Area (m²/g)</strong>: -</li><li><strong>Separation Mode:</strong> Ion Exchange</li><li><strong>Particle Size:</strong> 55</li><li><strong>Recommended Use: </strong>Extraction of weakly acidic compounds</li></ul><h4><strong>Starting Method</strong></h4><h5><strong>Strata SAX – Strong Anion-Exchange</strong></h5><ul><li><strong>Condition:</strong> 1 mL Methanol</li><li><strong>Equilibrate:</strong> 1 mL DI Water</li><li><strong>Load:</strong> Pretreated sample, pH 6-7</li><li><strong>Wash 1</strong>: 1 mL 25mM Ammonium Acetate Buffer, pH 6-7</li><li><strong>Wash 2</strong>: 1 mL Methanol, dry under vacuum for 2-5 min</li><li><strong>Elute: </strong>1 mL 5% Formic Acid in Methanol</li></ul><p>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.</p>

Phenomenex Strata Screen-A Solid Phase Extraction (SPE)

Incorporates the hydrophobic selectivity of a C8 phase and strong anion-exchange for the extraction of acidic drugs from biological matrices.

<p><strong>Mixed-Mode Solid Phase Extraction (SPE) Sorbent</strong></p><p>Incorporates the hydrophobic selectivity of a C8 phase and strong anion-exchange for the extraction of acidic drugs from biological matrices.</p><figure class="image"><img style="aspect-ratio:500/150;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_Screen_A_f370bdfd48.webp" alt="Phenomenex: Strata Screen-A" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_Screen_A_f370bdfd48.webp 245w," sizes="100vw" width="500" height="150"></figure><ul><li><strong>Surface Area (m²/g)</strong>: -</li><li><strong>Separation Mode:</strong> Multi-Mode</li><li><strong>Particle Size:</strong> 55</li><li><strong>Recommended Use: </strong>Extracts acidic drugs from biological matrices</li></ul><h4><strong>Starting Method</strong></h4><h5><strong>Strata Screen-A Strong Anion-Exchange</strong></h5><ul><li><strong>Condition:</strong> 1 mL Methanol</li><li><strong>Equilibrate:</strong> 1 mL Water</li><li><strong>Load:</strong> Pretreated sample</li><li><strong>Wash 1</strong>: 1 mL 25mM Ammonium Acetate Buffer, pH 6-7</li><li><strong>Wash 2</strong>: 1 mL Methanol, dry under vacuum for 2-5 min</li><li><strong>Elute: </strong>1 mL 5% Formic Acid in Methanol</li></ul><p>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.</p>

Phenomenex Strata Screen-C Solid Phase Extraction (SPE)

Incorporates the hydrophobic selectivity of a C8 phase and strong cation exchange for the extraction of basic drugs from biological matrices.

<p><strong>Strong Cation-Exchange Solid Phase Extraction (SPE)</strong></p><p>Incorporates the hydrophobic selectivity of a C8 phase and strong cation exchange for the extraction of basic drugs from biological matrices.</p><figure class="image"><img style="aspect-ratio:500/150;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_Screen_C_b60bb2b7e4.webp" alt="Phenomenex: Strata Screen-C" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_Screen_C_b60bb2b7e4.webp 245w," sizes="100vw" width="500" height="150"></figure><ul><li><strong>Surface Area (m²/g)</strong>: 500, m²/g, 500 m²/g</li><li><strong>Separation Mode:</strong> Multi-Mode</li><li><strong>Pore Size</strong>: 70</li><li><strong>Particle Size:</strong> 55</li><li><strong>Recommended Use: </strong>Extraction of basic drugs from biological matrixes</li></ul><h4><strong>Starting Method</strong></h4><h5><strong>Strata Screen-C Strong Cation-Exchange</strong></h5><ul><li><strong>Condition:</strong> 1 mL Methanol</li><li><strong>Equilibrate:</strong> 1 mL Acidified Water</li><li><strong>Load:</strong> Pretreated sample (acidified)</li><li><strong>Wash 1</strong>: 1 mL 0.1N HCl in Water</li><li><strong>Wash 2</strong>: 1 mL 0.1N HCl in Methanol, dry under vacuum for 2-5 min</li><li><strong>Elute: </strong>1 mL 5 % NH<sub>4</sub>OH in Methanol</li></ul><p>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.</p>

Phenomenex Strata Screen-C GF Solid Phase Extraction (SPE)

Optimized for gravity flow, this sorbent offers hydrophobic selectivity from a C8 phase and strong cation-exchange properties for the extraction of basic drugs.

<p><strong>Strong Cation-Exchange Solid Phase Extraction (SPE)</strong></p><p>Optimized for gravity flow, this sorbent offers hydrophobic selectivity from a C8 phase and strong cation-exchange properties for the extraction of basic drugs from biological matrixes. Offers the selectivity of Screen-C in a gravity flow particle size for viscous samples.</p><h4><strong>Starting Method</strong></h4><h5><strong>Strata Screen-C GF Strong Cation-Exchange</strong></h5><ul><li><strong>Condition:</strong> 1 mL Methanol</li><li><strong>Equilibrate:</strong> 1 mL Acidified Water</li><li><strong>Load:</strong> Pretreated sample (acidified)</li><li><strong>Wash 1</strong>: 1 mL 0.1N HCl in Water</li><li><strong>Wash 2</strong>: 1 mL 0.1N HCl in Methanol, dry under vacuum for 2-5 min</li><li><strong>Elute: </strong>1 mL 5 % NH<sub>4</sub>OH in Methanol</li></ul><p>Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.</p>

Phenomenex Zebron ZB-1HT Inferno GC Columns

Zebron Inferno column ZB-1HT provides true boiling point separation for hydrocarbon distillation methods.

<h4><strong>Robust Results Up to 430 ºC</strong></h4><ul><li>First non-metal columns stable to 430 °C</li><li>Provides true boiling point separation for hydrocarbon distillation methods</li><li>Longer lifetime with rugged high temperature, polyimide coated, fused silica tubing</li><li>Low activity, provides good peak shape for acidic and basic samples</li><li>Provides robust column performance for high temperature bake outs</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_zb_1ht_3c54563ddc.webp" alt="Phenomenex: Zebron-ZB-1HT" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_zb_1ht_3c54563ddc.webp 245w," sizes="100vw" width="500" height="150"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1_HT_Inferno_54cd995dba.jpg" alt="Phenomenex: Zebron™ ZB-1HT Inferno™" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1_HT_Inferno_54cd995dba.jpg 173w," sizes="100vw" width="651" height="587"></p><h4><strong>Recommended Use</strong></h4><p><strong>Rugged, high-temperature stability (up to 430 °C) for:</strong></p><ul><li>non-polar compounds</li><li>for high boilers</li><li>contaminants</li><li>carry-overs</li><li>high-temp bakeouts</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>High Boiling Petroleum Products</li><li>Simulated Distillation Methods</li><li>Long-Chained Hydrocarbons</li><li>High Molecular Weight Waxes</li><li>Polymers/Plastics</li><li>Motor Oils</li><li>Diesel Fuel</li></ul><h5><strong>Alternative To:</strong> Any 100 % Dimethylpolysiloxane Phase:</h5><ul><li>DB®-1ht</li><li>Rxi®-1HT</li><li>Petrocol 2887</li><li>CP-SimDist</li></ul><h3><strong>Phenomenex Zebron Inferno GC Columns</strong></h3><h4><strong>Overcome Traditional Obstacles</strong></h4><h5><strong>Challenge # 1: Short Fused Silica Column Lifetimes</strong></h5><p>Unlike Zebron™ Inferno™ GC columns, traditional fused silica columns are not equipped to handle prolonged exposure to<br>temperatures above 360 °C. At high temperatures, fused silica GC columns:</p><ul><li>Become inflexible and brittle</li><li>Break easily and cause costly replacement</li><li>Require more system downtime for maintenance</li><li>Can’t separate high molecular weight compounds</li></ul><h5><strong>Challenge # 2: Cumbersome Metal Column Tubing</strong></h5><p>Though metal columns have higher temperature limits than capillary columns, they are more difficult to use.</p><p><strong>Most metal columns:</strong></p><ul><li>Are inflexible and hard to use</li><li>Require special tubing cutters for installation</li><li>Are prone to leaks from expansion and contraction</li><li>Have active surfaces, giving poor peak shapes for acids and bases</li><li>Are incompatible with MS detectors</li></ul><h3><strong>How it works</strong></h3><p>Zebron™ Inferno™ columns offer enhanced performance where other columns fail. The two critical factors that allow for this are:</p><ul><li><h5><strong>Advanced ESC™ Bonding Technology</strong></h5></li></ul><p>At high temperature ranges, the stability of standard GC columns deteriorates, resulting in increased bleed. Zebron’s Engineered Self Cross-linking™ (ESC) bonding technology reinforces the stationary phase for enhanced column durability and extremely low bleed levels at high temperatures. <strong>The result:</strong> Inferno columns with the flexibility to perform for high temp oven ramps and bakeouts.</p><ul><li><strong>High Temperature Polyimide Coating</strong></li></ul><p>Standard polyimide resin pyrolyzes at temperatures above 360 °C, making the tubing unstable. Zebron Inferno columns use a temperature resistant polyimide resin that shows minimal thermal degradation, even at temperatures up to 430 °C*. This means longer column lifetime at elevated temperatures.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg" alt="Phenomenex: Zebron Inferno GC Columns - How it works" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg 245w," sizes="100vw" width="978" height="564"></p><h3><strong>Features of Zebron Inferno GC Columns</strong></h3><h4><strong>Extremely Low Bleed for Rugged Performance</strong></h4><ul><li>Longer column lifetime</li><li>Better reproducibility</li><li>Maximum sensitivity</li><li>More accurate quantitation</li></ul><h4><strong>Increased Column Lifetime with Enhanced Durability</strong></h4><ul><li>Less instrument downtime</li><li>More productivity</li><li>Lower laboratory costs</li></ul><h5><strong>Standard GC Columns Cannot Withstand High Temperature</strong></h5><p>After prolonged exposure to temperatures above 360 °C, most traditional GC columns become brittle and inflexible, often spontaneously breaking in the middle of a run. Work is stopped in order to change out the column and perform system maintenance. Unlike these fragile columns, ZebronTM InfernoTM columns have a thermally resistant polyimide coating for longer column lifetime at temperatures up to 430 °C. As a result, you get less instrument downtime, and higher productivity.</p><h4><strong>Greater Performance for High Boiling Compounds</strong></h4><ul><li>Better peak shape</li><li>Improved separation</li><li>More analytes detected</li></ul><p>Zebron™ Inferno™ columns have the inertness and temperature stability needed to separate high molecular weight compounds. These high boilers require a thermally rugged column with low bleed levels. Inferno columns provide optimal separation of these analytes.</p>

Phenomenex Zebron ZB-35HT Inferno GC Columns

Zebron Inferno column ZB-35HT is the first non-metal, 35 % phenyl column stable to 400 ˚C.

<h4><strong>High Temperature Stability for Mid-Polarity</strong></h4><ul><li>First non-metal, 35 % phenyl columns stable to 400 ˚C</li><li>Longer lifetime with rugged high temperature, polyimide coated, fused silica tubing</li><li>Robust column for high temperature analysis</li><li>Great for high molecular weight compounds</li><li>Eliminate carry-over with high temperature bake outs</li><li>Low activity, provides good peak shape for acidic and basic samples</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_35_HT_Inferno_GC_Column_773b8b1796.webp" alt="Phenomenex: Zebron ZB-35HT Inferno GC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_35_HT_Inferno_GC_Column_773b8b1796.webp 245w," sizes="100vw" width="500" height="150"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_35_HT_Inferno_79e3acc7c9.jpg" alt="Phenomenex: Zebron™ ZB-35HT Inferno™" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_35_HT_Inferno_79e3acc7c9.jpg 167w," sizes="100vw" width="603" height="564"></p><h4><strong>Recommended Use</strong></h4><p><strong>Intermediate polarity with high temperature stability (up to 400 °C) for:</strong></p><ul><li>high boilers</li><li>contaminants</li><li>carry-overs</li><li>high-temp bakeouts</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>Amines</li><li>Aroclors</li><li>Chemicals</li><li>Drugs of Abuse</li><li>EPA Methods 508, 608, 8081, 8141, 8151</li><li>Pesticides</li><li>Pharmaceuticals</li><li>Semi-volatiles</li><li>Steroids</li></ul><h5><strong>Alternative to:</strong> Any 35 % Phenyl 65 % Dimethylpolysiloxane Phase:</h5><ul><li>DB®-35ms</li><li>SPB-680</li><li>MDN-35</li><li>DC-35</li><li>Rtx-35&nbsp;</li><li>SPB®-35</li><li>Rtx®-35MS</li><li>007-11</li><li>EC-35</li><li>BPX35</li><li>AT-35</li><li>HP-35ms</li><li>Sup-Herb</li><li>OV-11</li><li>HP-35</li><li>BPX608</li></ul><h3><strong>Phenomenex Zebron Inferno GC Columns</strong></h3><h4><strong>Overcome Traditional Obstacles</strong></h4><h5><strong>Challenge # 1: Short Fused Silica Column Lifetimes</strong></h5><p>Unlike Zebron™ Inferno™ GC columns, traditional fused silica columns are not equipped to handle prolonged exposure to<br>temperatures above 360 °C. At high temperatures, fused silica GC columns:</p><ul><li>Become inflexible and brittle</li><li>Break easily and cause costly replacement</li><li>Require more system downtime for maintenance</li><li>Can’t separate high molecular weight compounds</li></ul><h5><strong>Challenge # 2: Cumbersome Metal Column Tubing</strong></h5><p>Though metal columns have higher temperature limits than capillary columns, they are more difficult to use.</p><p><strong>Most metal columns:</strong></p><ul><li>Are inflexible and hard to use</li><li>Require special tubing cutters for installation</li><li>Are prone to leaks from expansion and contraction</li><li>Have active surfaces, giving poor peak shapes for acids and bases</li><li>Are incompatible with MS detectors</li></ul><h3><strong>How it works</strong></h3><p>Zebron™ Inferno™ columns offer enhanced performance where other columns fail. The two critical factors that allow for this are:</p><ul><li><h5><strong>Advanced ESC™ Bonding Technology</strong></h5></li></ul><p>At high temperature ranges, the stability of standard GC columns deteriorates, resulting in increased bleed. Zebron’s Engineered Self Cross-linking™ (ESC) bonding technology reinforces the stationary phase for enhanced column durability and extremely low bleed levels at high temperatures. <strong>The result:</strong> Inferno columns with the flexibility to perform for high temp oven ramps and bakeouts.</p><ul><li><strong>High Temperature Polyimide Coating</strong></li></ul><p>Standard polyimide resin pyrolyzes at temperatures above 360 °C, making the tubing unstable. Zebron Inferno columns use a temperature resistant polyimide resin that shows minimal thermal degradation, even at temperatures up to 430 °C*. This means longer column lifetime at elevated temperatures.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg" alt="Phenomenex: Zebron Inferno GC Columns - How it works" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg 245w," sizes="100vw" width="978" height="564"></p><h3><strong>Features of Zebron Inferno GC Columns</strong></h3><h4><strong>Extremely Low Bleed for Rugged Performance</strong></h4><ul><li>Longer column lifetime</li><li>Better reproducibility</li><li>Maximum sensitivity</li><li>More accurate quantitation</li></ul><h4><strong>Increased Column Lifetime with Enhanced Durability</strong></h4><ul><li>Less instrument downtime</li><li>More productivity</li><li>Lower laboratory costs</li></ul><h5><strong>Standard GC Columns Cannot Withstand High Temperature</strong></h5><p>After prolonged exposure to temperatures above 360 °C, most traditional GC columns become brittle and inflexible, often spontaneously breaking in the middle of a run. Work is stopped in order to change out the column and perform system maintenance. Unlike these fragile columns, ZebronTM InfernoTM columns have a thermally resistant polyimide coating for longer column lifetime at temperatures up to 430 °C. As a result, you get less instrument downtime, and higher productivity.</p><h4><strong>Greater Performance for High Boiling Compounds</strong></h4><ul><li>Better peak shape</li><li>Improved separation</li><li>More analytes detected</li></ul><p>Zebron™ Inferno™ columns have the inertness and temperature stability needed to separate high molecular weight compounds. These high boilers require a thermally rugged column with low bleed levels. Inferno columns provide optimal separation of these analytes.</p>

Phenomenex Zebron ZB-5HT Inferno GC Columns

Robust column for high temperature bake outs and analysis, such as biodiesel, long-chain hydrocarbons, polymers, and high molecular weight compounds.

<h4><strong>Robust Results Up to 430 °C</strong></h4><ul><li>First non-metal columns stable to 430 °C</li><li>Robust column for high temperature bake outs and analysis, such as biodiesel, long-chain hydrocarbons, polymers, and high molecular weight compounds</li><li>Provides true boiling point separation for hydrocarbon distillation methods</li><li>Longer lifetime with rugged high temperature, polyimide coated, fused silica tubing</li><li>Low activity, provides good peak shape for acidic and basic samples</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_zb_5ht_750bf39b6e.webp" alt="Phenomenex: Zebron-ZB-5HT" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_zb_5ht_750bf39b6e.webp 245w," sizes="100vw" width="500" height="150"></p><figure class="image"><img style="aspect-ratio:676/573;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_5_HT_Inferno_0aa668bf75.jpg" alt="Phenomenex: Zebron ZB-5HT Inferno" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_5_HT_Inferno_0aa668bf75.jpg 184w," sizes="100vw" width="676" height="573"></figure><h4><strong>Recommended Use</strong></h4><p><strong>True boiling point separation for:</strong></p><ul><li>hydrocarbon distillation methods</li><li>high boilers</li><li>contaminants or carryovers</li><li>high temperature stable (430 °C)</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>High Boiling Petroleum Products</li><li>Triglycerides</li><li>Simulated Distillation Methods</li><li>Diesel Fuel</li><li>Long-Chained Hydrocarbons</li><li>Motor Oils</li><li>Polymers/Plastics</li><li>Surfactants</li><li>High Molecular Weight Waxes</li></ul><h5><strong>Alternative to:</strong> Any 5 % Phenyl 95 % Dimethylpolysiloxane Phase:</h5><ul><li>DB-5ht</li><li>VF-5ht</li><li>HT-5&nbsp;</li><li>Stx®-5HT&nbsp;</li><li>XTI®-5HT</li></ul><h3><strong>Phenomenex Zebron Inferno GC Columns</strong></h3><h4><strong>Overcome Traditional Obstacles</strong></h4><h5><strong>Challenge # 1: Short Fused Silica Column Lifetimes</strong></h5><p>Unlike Zebron™ Inferno™ GC columns, traditional fused silica columns are not equipped to handle prolonged exposure to<br>temperatures above 360 °C. At high temperatures, fused silica GC columns:</p><ul><li>Become inflexible and brittle</li><li>Break easily and cause costly replacement</li><li>Require more system downtime for maintenance</li><li>Can’t separate high molecular weight compounds</li></ul><h5><strong>Challenge # 2: Cumbersome Metal Column Tubing</strong></h5><p>Though metal columns have higher temperature limits than capillary columns, they are more difficult to use.</p><p><strong>Most metal columns:</strong></p><ul><li>Are inflexible and hard to use</li><li>Require special tubing cutters for installation</li><li>Are prone to leaks from expansion and contraction</li><li>Have active surfaces, giving poor peak shapes for acids and bases</li><li>Are incompatible with MS detectors</li></ul><h3><strong>How it works</strong></h3><p>Zebron™ Inferno™ columns offer enhanced performance where other columns fail. The two critical factors that allow for this are:</p><ul><li><h5><strong>Advanced ESC™ Bonding Technology</strong></h5></li></ul><p>At high temperature ranges, the stability of standard GC columns deteriorates, resulting in increased bleed. Zebron’s Engineered Self Cross-linking™ (ESC) bonding technology reinforces the stationary phase for enhanced column durability and extremely low bleed levels at high temperatures. <strong>The result:</strong> Inferno columns with the flexibility to perform for high temp oven ramps and bakeouts.</p><ul><li><strong>High Temperature Polyimide Coating</strong></li></ul><p>Standard polyimide resin pyrolyzes at temperatures above 360 °C, making the tubing unstable. Zebron Inferno columns use a temperature resistant polyimide resin that shows minimal thermal degradation, even at temperatures up to 430 °C*. This means longer column lifetime at elevated temperatures.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg" alt="Phenomenex: Zebron Inferno GC Columns - How it works" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg 245w," sizes="100vw" width="978" height="564"></p><h3><strong>Features of Zebron Inferno GC Columns</strong></h3><h4><strong>Extremely Low Bleed for Rugged Performance</strong></h4><ul><li>Longer column lifetime</li><li>Better reproducibility</li><li>Maximum sensitivity</li><li>More accurate quantitation</li></ul><h4><strong>Increased Column Lifetime with Enhanced Durability</strong></h4><ul><li>Less instrument downtime</li><li>More productivity</li><li>Lower laboratory costs</li></ul><h5><strong>Standard GC Columns Cannot Withstand High Temperature</strong></h5><p>After prolonged exposure to temperatures above 360 °C, most traditional GC columns become brittle and inflexible, often spontaneously breaking in the middle of a run. Work is stopped in order to change out the column and perform system maintenance. Unlike these fragile columns, ZebronTM InfernoTM columns have a thermally resistant polyimide coating for longer column lifetime at temperatures up to 430 °C. As a result, you get less instrument downtime, and higher productivity.</p><h4><strong>Greater Performance for High Boiling Compounds</strong></h4><ul><li>Better peak shape</li><li>Improved separation</li><li>More analytes detected</li></ul><p>Zebron™ Inferno™ columns have the inertness and temperature stability needed to separate high molecular weight compounds. These high boilers require a thermally rugged column with low bleed levels. Inferno columns provide optimal separation of these analytes.</p>

Phenomenex Zebron ZB-XLB-HT Inferno GC Columns

Zebron ZB-XLB-HT Inferno is a rugged, non-metal si-arylene GC column stable to 400 ˚C

<h4><strong>High Temp Stability, Low Bleed</strong></h4><ul><li>Rugged, non-metal si-arylene GC column stable to 400 ˚C</li><li>Robust column for high temperature bake outs and analysis, such as high molecular weight compounds</li><li>Provides unique selectivity for conformational analyses</li><li>Longer lifetime with high temperature, polyimide coated, fused silica tubing</li><li>Low activity, provides good peak shape for acidic and basic samples</li><li>Good tool for general screening to identify unknown samples</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_XLB_HT_Inferno_9541a754ac.jpg" alt="Phenomenex: Zebron ZB-XLB-HT Inferno" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_XLB_HT_Inferno_9541a754ac.jpg 165w," sizes="100vw" width="599" height="564"></p><h4><strong>Recommended Use</strong></h4><ul><li>Used confirmation of pesticides, PCB, or other environmental samples</li><li>Robust column performance for high temperature bakeouts</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>EPA Methods</li><li>Herbicides</li><li>Pesticides</li><li>Polychlorinated Biphenyls (PCBs)</li></ul><h5><strong>Similar* To:</strong></h5><ul><li>MDN-12</li><li>DB-XLB</li><li>Rtx-XLB</li></ul><p><strong>*Not exact equivalent, selectivity may differ</strong></p><h3><strong>Phenomenex Zebron Inferno GC Columns</strong></h3><h4><strong>Overcome Traditional Obstacles</strong></h4><h5><strong>Challenge # 1: Short Fused Silica Column Lifetimes</strong></h5><p>Unlike Zebron™ Inferno™ GC columns, traditional fused silica columns are not equipped to handle prolonged exposure to<br>temperatures above 360 °C. At high temperatures, fused silica GC columns:</p><ul><li>Become inflexible and brittle</li><li>Break easily and cause costly replacement</li><li>Require more system downtime for maintenance</li><li>Can’t separate high molecular weight compounds</li></ul><h5><strong>Challenge # 2: Cumbersome Metal Column Tubing</strong></h5><p>Though metal columns have higher temperature limits than capillary columns, they are more difficult to use.</p><p><strong>Most metal columns:</strong></p><ul><li>Are inflexible and hard to use</li><li>Require special tubing cutters for installation</li><li>Are prone to leaks from expansion and contraction</li><li>Have active surfaces, giving poor peak shapes for acids and bases</li><li>Are incompatible with MS detectors</li></ul><h3><strong>How it works</strong></h3><p>Zebron™ Inferno™ columns offer enhanced performance where other columns fail. The two critical factors that allow for this are:</p><ul><li><h5><strong>Advanced ESC™ Bonding Technology</strong></h5></li></ul><p>At high temperature ranges, the stability of standard GC columns deteriorates, resulting in increased bleed. Zebron’s Engineered Self Cross-linking™ (ESC) bonding technology reinforces the stationary phase for enhanced column durability and extremely low bleed levels at high temperatures. <strong>The result:</strong> Inferno columns with the flexibility to perform for high temp oven ramps and bakeouts.</p><ul><li><strong>High Temperature Polyimide Coating</strong></li></ul><p>Standard polyimide resin pyrolyzes at temperatures above 360 °C, making the tubing unstable. Zebron Inferno columns use a temperature resistant polyimide resin that shows minimal thermal degradation, even at temperatures up to 430 °C*. This means longer column lifetime at elevated temperatures.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg" alt="Phenomenex: Zebron Inferno GC Columns - How it works" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg 245w," sizes="100vw" width="978" height="564"></p><h3><strong>Features of Zebron Inferno GC Columns</strong></h3><h4><strong>Extremely Low Bleed for Rugged Performance</strong></h4><ul><li>Longer column lifetime</li><li>Better reproducibility</li><li>Maximum sensitivity</li><li>More accurate quantitation</li></ul><h4><strong>Increased Column Lifetime with Enhanced Durability</strong></h4><ul><li>Less instrument downtime</li><li>More productivity</li><li>Lower laboratory costs</li></ul><h5><strong>Standard GC Columns Cannot Withstand High Temperature</strong></h5><p>After prolonged exposure to temperatures above 360 °C, most traditional GC columns become brittle and inflexible, often spontaneously breaking in the middle of a run. Work is stopped in order to change out the column and perform system maintenance. Unlike these fragile columns, ZebronTM InfernoTM columns have a thermally resistant polyimide coating for longer column lifetime at temperatures up to 430 °C. As a result, you get less instrument downtime, and higher productivity.</p><h4><strong>Greater Performance for High Boiling Compounds</strong></h4><ul><li>Better peak shape</li><li>Improved separation</li><li>More analytes detected</li></ul><p>Zebron™ Inferno™ columns have the inertness and temperature stability needed to separate high molecular weight compounds. These high boilers require a thermally rugged column with low bleed levels. Inferno columns provide optimal separation of these analytes.</p>

Phenomenex Zebron ZB-1plus GC Columns

Zebron ZB-1plus is a very low bleed (MS Certified) phase especially suited to high sensitivity GC-MS

<h4><strong>MS Certified “1” Phase</strong></h4><ul><li><strong>Very low bleed</strong> (MS Certified) phase especially suited to high sensitivity GC-MS</li><li><strong>Extremely inert</strong> for active compounds such as drugs, pesticides, or acids and bases</li><li><strong>Improved signal-to-noise ratio</strong> for better sensitivity and mass spectral integrity</li><li>Equivalent selectivity to <strong>100 % dimethylpolysiloxane phases</strong></li></ul><p><strong>We tested the ZB-1PLUS column bleed profile against other “MS” columns on the market – ZB-1PLUS shows the lowest bleed, even at temperatures up to 360 °C.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1plus_Lower_Column_Bleed_e761722aea.jpg" alt="Phenomenex: Zebron ZB-1plus - Lower Column Bleed" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1plus_Lower_Column_Bleed_e761722aea.jpg 213w," sizes="100vw" width="1000" height="733"></p><h4><strong>Recommended Use</strong></h4><ul><li>Especially suited to high sensitivity GC-MS and extremely inert for active compounds</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>Acids</li><li>Amines</li><li>Drugs</li><li>EPA Methods (1668)</li><li>Diesel Fuel</li><li>Essential Oils</li><li>Flavors &amp; Fragrances</li><li>Oxygenates and GROs</li><li>PCBs</li><li>Pesticides</li><li>Solvent Impurities</li><li>Sulfur Compounds (Light)</li></ul><h5><strong>Upgrade to ZB-1<sub>PLUS</sub> from any 100 % dimethylpolysiloxane phase:</strong></h5><p><strong>Agilent®</strong></p><ul><li>DB®-1</li><li>DB-1ms</li><li>DB-1ms Ultra Inert</li><li>HP-1</li><li>HP-1ms</li><li>HP-1ms Ultra Inert</li><li>VF-1ms</li><li>CP-Sil 5 CB</li><li>Ultra 1</li></ul><p><strong>Restek®</strong></p><ul><li>Rtx®-1</li><li>Rtx-1ms</li><li>Rxi®-1ms</li></ul><p><strong>SGE®</strong></p><ul><li>BP1</li><li>SolGel-1ms™</li></ul><p><strong>Supelco®</strong></p><ul><li>PB®-1</li><li>SE-30</li><li>MET-1</li><li>MDN-1</li><li>Equity®-1</li></ul><h3><strong>Phenomenex Zebron PLUS GC Columns</strong></h3><h4><strong>What’s in the Zebron™ PLUS?</strong></h4><ul><li>Active sites on a GC column’s surface can result in analyte adsorption and degradation, which negatively affect peak shape and response.</li><li>To reduce potential surface activity, <strong>Zebron PLUS phases</strong> (ZB-1plus, ZB-5plus, ZB-5MSplus, and ZB-624plus) are designed with a rigorous fused silica deactivation process that improves inertness and peak shapes for troublesome compounds</li><li>Zebron ZB-WAX<sub>PLUS</sub> is specially designed for <strong>100% aqueous stability</strong>, <strong>enhanced resolution</strong> and <strong>better reproducibility</strong>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg" alt="Phenomenex: Zebron PLUS GC Column phase" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg 245w," sizes="100vw" width="1191" height="454"></p>

Phenomenex Zebron ZB-5MSplus GC Columns

Zebron ZB-5MSplus is a low bleed (MS Certified) and well-suited to high sensitivity GC-MS and GC-MS/MS work

<h4><strong>The Next Generation of Inertness</strong></h4><ul><li>The next generation of inertness for specialty chemical, forensic, toxicology, and food testing applications</li><li>Specialized deactivation for versatile 5 % phenylarylene selectivity with improved sensitivity</li><li>Low bleed (MS Certified) and well-suited to high sensitivity GC-MS and GC-MS/MS work</li></ul><h4><strong>Engineered for High Performance</strong></h4><h5><strong>Improved Inertness, Better Peak Shape, Low Bleed, and Aqueous Stability</strong></h5><p>Active sites on a GC column’s surface can result in analyte adsorption and degradation, negatively affecting peak shape and response. To reduce potential surface activity, Zebron ZB-5MSplus is designed with a <strong>rigorous fused silica deactivation process </strong>that improves inertness for troublesome compounds. Instantly achieve higher responses for active compounds compared to your current 5ms phase column, without changing your selectivity.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_5_M_Splus_Improved_Inertness_Better_Peak_Shape_Low_Bleed_and_Aqueous_Stability_e424743162.jpg" alt="Phenomenex: Zebron ZB-5MSplus - Improved Inertness, Better Peak Shape, Low Bleed, and Aqueous Stability" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_5_M_Splus_Improved_Inertness_Better_Peak_Shape_Low_Bleed_and_Aqueous_Stability_e424743162.jpg 157w," sizes="100vw" width="905" height="901"></p><h5><strong>Better peak shape</strong></h5><figure class="image"><img style="aspect-ratio:1243/592;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_5_MS_Plus_vs_other_5_MS_Columns_e7a202e862.jpg" alt="Phenomenex: Zebron ZB-5MS Plus vs other 5MS Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_5_MS_Plus_vs_other_5_MS_Columns_e7a202e862.jpg 245w," sizes="100vw" width="1243" height="592"></figure><h4><strong>Recommended Use</strong></h4><ul><li>Specialized deactivation for versatile 5% Phenyl-Arylene selectivity with improved sensitivity</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>Acids</li><li>Alkaloids</li><li>Amines</li><li>Drugs</li><li>Essential Oils</li><li>Flavors</li><li>Halo-hydrocarbons</li><li>Pesticides</li><li>Phenols</li><li>Residual Solvents</li><li>Solvent Impurities</li></ul><h5><strong>Upgrade to ZB-5MS<sub>PLUS</sub> from any 5 % phenyl or 5 % phenyl-arylene / 95 % dimethylpolysiloxane phase:</strong></h5><h5><strong>Agilent®</strong></h5><ul><li>DB®-5ms</li><li>DB-5ms Ultra Inert</li><li>HP-5ms</li><li>HP-5ms Ultra Inert</li><li>VF-5ms</li></ul><h5><strong>Restek®</strong></h5><ul><li>Rxi®-5Sil MS</li></ul><h5><strong>Supelco®</strong></h5><ul><li>SLB®-5ms</li></ul><h3><strong>Phenomenex Zebron PLUS GC Columns</strong></h3><h4><strong>What’s in the Zebron™ PLUS?</strong></h4><ul><li>Active sites on a GC column’s surface can result in analyte adsorption and degradation, which negatively affect peak shape and response.</li><li>To reduce potential surface activity, <strong>Zebron PLUS phases</strong> (ZB-1plus, ZB-5plus, ZB-5MSplus, and ZB-624plus) are designed with a rigorous fused silica deactivation process that improves inertness and peak shapes for troublesome compounds</li><li>Zebron ZB-WAX<sub>PLUS</sub> is specially designed for <strong>100% aqueous stability</strong>, <strong>enhanced resolution</strong> and <strong>better reproducibility</strong>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg" alt="Phenomenex: Zebron PLUS GC Column phase" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_PLUS_GC_Column_phase_522f5f8817.jpg 245w," sizes="100vw" width="1191" height="454"></p>

Products focused on Consumables - page 33

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