ISC 2026 - Day 2

<h4>What if you could compress 179 days of grueling laboratory workflow into just 14 hours?</h4>In this episode of ‪ChromatographyTalk‬, ‪Organomation‬ General Manager David Oliva sits down with analytical chemist Laura Penabad to discuss her groundbreaking new research in biocatalysis and high-throughput screening. Evolving engineered enzymes typically requires checking thousands of variants—a massive bottleneck when traditional Liquid Chromatography-Mass Spectrometry (LC-MS) runs take minutes per sample. Laura reveals how her team built a modular screening platform that shatters this limitation, running samples 128 times faster than standard methods without sacrificing analytical accuracy.Laura breaks down the "orchestra" of technologies making this possible, including coupling nanoliter droplet microfluidics with Cyclic Ion Mobility-Mass Spectrometry (cIM-MS) to separate complex chemical isomers in milliseconds. She also shares the chaotic but triumphant behind-the-scenes stories of her PhD journey—from presenting a "comically bad" early poster at ASMS to recruiting an undergraduate mechanical engineer to build custom automation software from scratch.If you are an early-career researcher, a mass spec enthusiast, or curious about the future of synthetic biology and machine learning in chemistry, this episode is packed with invaluable intuition and advice.<h3>Video Transcription</h3><h4>From Months to Hours: Droplet Ion Mobility–MS for Biocatalysis Screening</h4>High-throughput screening is central to directed enzyme evolution, but conventional analytical workflows can create a difficult compromise: extremely fast screens often provide limited structural information, while techniques such as LC-MS offer much richer chemical insight at the cost of throughput. In a recent interview, analytical chemist Laura described how her work with droplet-based cyclic ion mobility mass spectrometry is helping bridge that gap—providing rapid analysis while retaining the ability to distinguish structurally similar products.Her research grew from an initially modest proof of concept into a screening platform capable of analyzing a 96-well plate in roughly ten minutes. The resulting workflow was approximately 128 times faster than a conventional three-minute LC-MS analysis, opening new possibilities for directed evolution campaigns in which thousands of enzyme variants need to be evaluated.<h4>Directed evolution needs better analytical screening</h4>Biocatalysis takes advantage of enzymes as highly selective catalysts capable of performing reactions under relatively mild conditions. Directed evolution extends those capabilities by deliberately modifying enzyme sequences, expressing large numbers of variants, screening their activity, and using the best-performing mutants as starting points for subsequent rounds of evolution.The process can be repeated multiple times, progressively steering an enzyme toward improved activity, altered substrate specificity, or even chemistry that does not occur naturally.But the effectiveness of directed evolution depends heavily on the screening step. The more variants that can be analyzed—and the more useful chemical information that can be collected for each one—the more effectively researchers can explore the enormous sequence space available to an enzyme.For Laura, this created a clear analytical challenge: develop a screening platform that was substantially faster than conventional chromatographic analysis without sacrificing the structural discrimination needed for chemically similar products.<h4>From an imperfect first experiment to a working platform</h4>The project did not begin with a polished high-throughput workflow.Laura recalled looking back at her 2023 ASMS poster, where the early system was still working with standards rather than true isomeric samples. Droplet introduction was slow—around six seconds per droplet—and the signals were far from the ideal reproducible, square, flat-topped profiles expected from replicate droplets.Nevertheless, simply producing a droplet signal represented an important first milestone.The decisive change came when the project stopped being treated merely as a demonstration that droplet ion mobility–MS could work and instead became a deliberate effort to build a robust screening platform.Laura approached the problem in modules. First came reliable droplet introduction. Then the ion mobility separation method. Quantification became another independent component. Matrix effects were introduced later, gradually making the system resemble the conditions expected with real screening samples.Each layer was tested before another was added.This stepwise strategy became one of the central principles of the project: rather than attempting to optimize the entire system simultaneously, individual components were developed, challenged, and then assembled into an increasingly realistic workflow.<h4>Finding the middle ground between speed and structural information</h4>One of the biggest analytical problems in high-throughput screening is distinguishing products with the same nominal or exact mass.Constitutional isomers may contain the same atoms and therefore generate the same mass-to-charge ratio, while differing only in how functional groups are arranged within the molecular structure. Very rapid optical or mass-based screens may therefore struggle to distinguish them.Traditional LC-MS can solve many of these problems through chromatographic separation, but a several-minute analysis rapidly becomes impractical when thousands of enzyme variants must be screened.Ion mobility offered Laura’s team another option.Rather than separating compounds on a chromatographic timescale, ion mobility can differentiate ions according to their gas-phase behavior on a much shorter timescale. In the workflow described in the interview, this created a useful compromise: not the kilohertz throughput possible with some simple screening technologies, but dramatically faster structural differentiation than conventional LC-MS.The goal was therefore not simply to achieve the fastest possible screen, but to find a middle-throughput analytical regime with enough resolving power to answer chemically meaningful questions.<h4>A 96-well plate in about ten minutes</h4>That strategy eventually produced one of the most striking results of the project.The droplet cyclic ion mobility–MS platform processed a 96-well plate in roughly ten minutes, while maintaining quantitative results comparable with the conventional LC-MS workflow used for comparison. According to the interview, this represented an approximately 128-fold increase in analysis speed relative to a three-minute LC-MS run.Laura described the successful plate experiment less as a surprise than as confirmation that the modular development strategy had worked.Before reaching that point, the workflow had already been challenged through a sequence of increasingly demanding experiments: droplet formation, ion mobility separation, calibration, matrix-containing calibration, and cross-testing analytes at different concentrations. By the time the complete plate was analyzed, each individual part of the analytical system had already been tested under progressively more realistic conditions.<h4>What does that speed mean for directed evolution?</h4>The impact becomes even clearer when the workflow is considered at the scale of an entire directed-evolution campaign.Laura’s manuscript estimated that a five-round campaign involving 5,000 variants would require approximately 179 days using the conventional LC-MS workflow but only about 14 hours using the new platform.Compressing months of analytical work into less than a day has consequences beyond laboratory productivity.It allows researchers to screen more enzyme variants and therefore sample a larger portion of sequence space. But the resulting datasets may also become increasingly valuable for computational approaches.Rather than retaining information only about the best-performing enzyme variant, researchers can preserve data describing variants that performed poorly as well as those that succeeded. When genotype and phenotype information remain linked through the well-plate workflow, these larger datasets can potentially provide richer input for machine-learning models designed to guide subsequent rounds of enzyme evolution.Faster analysis therefore does more than accelerate an existing experiment—it can change the scale and design of the experiment itself.<h4>Balancing ion mobility resolution and signal</h4>Increasing cyclic ion mobility separation time can improve resolution, but it also introduces an important trade-off: additional passes can reduce signal.Laura optimized this balance experimentally by continuously infusing mixtures containing both isomers and progressively adjusting the ion mobility conditions. After tuning parameters such as wave height and velocity, increasing the separation to three passes provided baseline resolution at the high analyte concentrations used during method development.<blockquote>Concentration, however, also mattered.</blockquote>At higher ion populations, space-charge effects could broaden peaks and reduce the baseline separation. This meant that the optimal number of passes could not be selected independently of the concentration range required by the final assay.Her broader advice for optimization is therefore application-driven: decide first what the analytical method actually needs to accomplish.More speed will almost always require sacrificing something—resolution, signal intensity, quantitative precision, or another performance parameter. The key is to identify which compromise the application can tolerate and then optimize the system around that requirement.<h4>Solving droplet carryover with a practical compromise</h4>Droplet-based workflows present their own engineering challenges, including carryover between neighboring samples.In Laura’s system, analytes showed little tendency to partition into the fluorinated oil separating aqueous droplets within the Teflon tubing. The more troublesome carryover occurred closer to electrospray ionization, where a small amount of sample could remain associated with the interface and appear when the next droplet arrived.Rather than adding excessive engineering complexity to an already elaborate platform, the researchers adopted a pragmatic solution: a sacrificial wash droplet between analytical samples.It is an example of a recurring theme throughout the project. The objective was not to construct the theoretically most sophisticated droplet system, but to create a screening workflow that remained sufficiently robust, reproducible, and practical for large numbers of samples.<h4>High-throughput analysis also requires high-throughput data processing</h4>Accelerating the mass spectrometry experiment created another bottleneck: the data.The instrument produced a continuous intensity-versus-time trace rather than a neatly organized well-plate dataset. With small experiments, Laura could manually identify individual droplets and process the results in spreadsheets. That approach quickly became unrealistic as sample numbers increased.The solution emerged through collaboration with an undergraduate mentee, Aiden, who helped develop a dedicated software tool for processing the continuous traces.Laura defined how the software should behave and how the analytical information should be organized, while Aiden developed the computational implementation. The workflow itself was subsequently adjusted to make automated data processing more reliable—for example, by introducing marker columns that allowed the software to recognize the end of each plate row.The resulting tool can accept the acquired traces together with information about plate dimensions and replicates and automatically return parameters including peak identity, duration, and the corresponding well position. A later version also generated an automatically populated heat map.The experience illustrates how improving analytical throughput often requires simultaneous development of instrumentation, experimental design, and informatics. Making the measurement faster is useful only if the resulting data can be processed at a comparable speed.<h4>Mentoring became part of the scientific process</h4>The software project also reflects another theme Laura emphasized throughout the interview: the value of mentoring.Several younger researchers contributed directly to the development of the final platform. Laura described mentees not simply as additional hands in the laboratory but as scientists capable of proposing their own hypotheses and experimental ideas.Working with undergraduate researchers also influenced the way she organized experiments.Because their available laboratory time was limited, each task needed to have a clear purpose. That encouraged a more disciplined approach to experimental planning: instead of performing experiments simply because they could be done, the team had to ask which experiment would most efficiently answer the next important question.In that sense, mentoring became another mechanism for improving the research itself.<h4>The next step: continuous, automated screening</h4>Despite the dramatic increase in analytical speed, the current workflow still includes manual operations such as loading tubing and connecting the sample stream to the mass spectrometer.The next engineering challenge is therefore automation.Laura described ongoing work using the Venturi effect to pull samples directly from wells into the droplet system. Building on previous work in the laboratory with 96-well plates, she has already tested this approach with as many as 2,000 samples.The long-term direction is clear: continuous and robust droplet generation, automated handling of thousands of samples, rapid ion mobility separation, mass spectrometric detection, and automated reconstruction of the resulting data into plate-based outputs.Combining those elements could move the system closer to the type of large-scale screening required for increasingly ambitious biocatalysis campaigns.<h4>Learning mass spectrometry one problem at a time</h4>Laura also reflected on the broader experience of developing the platform during her PhD.Ion mobility and mass spectrometry initially appeared intimidating, particularly because they combine concepts from analytical chemistry, physical chemistry, separations, instrumentation, and electrical engineering. What eventually changed was not simply learning more facts, but developing the ability to move repeatedly between theory and experiment.An unexpected result sends the researcher back to the underlying theory. A better understanding suggests a modified experiment. That experiment creates another observation, gradually building intuition about how the system behaves.Her advice to early-career scientists is therefore to accept that this process takes time.Advanced analytical techniques may initially appear overwhelming, but understanding develops incrementally through repeated interaction between theory, experimentation, failure, and refinement. Equally important, she emphasized the role of the supportive ion mobility–mass spectrometry community in making a technically demanding field more approachable for young researchers.From the first inconsistent droplets to a platform capable of processing thousands of samples, that iterative mindset ultimately shaped the entire project.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

Droplet Cyclic Ion Mobility Mass Spec: Compressing Months of Enzyme Screening Into Just 14 Hours

ISC 2026 - Day 3

Article

Events

Video

Scientists

Interview

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Thermo Scientific Niton XL3t XRF Analyzer

Perform nondestructive testing and get results in seconds for metal analysis, mining and exploration and lead paint testing for toys and consumer goods using handheld analyzers.

<div><div>When you need nondestructive testing with results in seconds for metal analysis, mining and exploration, and lead paint testing for toys and consumer goods, the Thermo Scientific™ Niton™ XL3t XRF Analyzer is the definitive tool for scrap metal recycling, casting and fabrication, manufacturing QA/QC and positive material identification.&nbsp;Get real-time compliance testing, including screening of incoming materials and outgoing finished goods, for the Consumer Product Safety Improvement Act (CPSIA), Proposition 65, Restriction of Hazardous Substances (RoHS) and other regulations.</div><div>The feature-leading, handheld Niton XL3t XRF Analyzer offers features engineered to improve your productivity and profitability.</div><h3>⚙️ Features</h3><ul><li>High sensitivity and measurement accuracy.</li><li>Lower detection limits for higher-Z elements, with additional elements Mg, Al, Si and P via helium purge.</li><li>Standard analytical range: 25 elements from S to U.</li><li>Optional CCD camera for visually identifying and recording images of samples.</li><li>A user-selectable 3mm small spot to locate areas of interest on a sample.</li><li>Flip-up, color, touch-screen display.</li><li>Ergonomic design.</li><li>Easy-to-use software.</li><li>50 kV x-ray tube provides approximately twice the x-ray flux of a 40 kV x-ray tube.</li><li>Hotfoot hot surface adaptor allows testing in petrochemical refineries up to 842°F (450°C).</li></ul></div><div><h3>🔗 Connectivity</h3><ul><li>Integrated USB and Bluetooth™ communications provide direct data transfer to your PC or networked storage device. &nbsp;</li><li>Standard Thermo Scientific™ Niton Data Transfer (NDT™) PC software allows you to: &nbsp;<ul><li>Set operator permissions &nbsp;</li><li>Generate custom reports &nbsp;</li><li>Print certificates of analysis &nbsp;</li><li>Remotely monitor and control the instrument from your PC &nbsp;</li></ul></li><li>Optional accessories: Bluetooth barcode reader, Bluetooth printer, Bluetooth GPS</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_3t_XRF_Analyzer_b0796bdd58.jpg" alt="Thermo Scientific™ Niton™ XL3t XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_3t_XRF_Analyzer_b0796bdd58.jpg 94w," sizes="100vw" width="650" height="1083"><h3>📏 Specifications</h3><ul><li>Applications: Elemental Analysis</li><li>Available Analytical Modes: Varies by Application<ul><li>Alloy Modes: Metal Alloy, Electronics Alloy, Precious Metals</li><li>Bulk Modes: Mining, Soil</li><li>Plastic Modes: RoHS Plastics, Toy and Consumer Goods Plastics, TestAll Painted Products</li><li>Other Modes: Lead Paint, Thin Sample</li></ul></li><li>Data Memory: 32Mb internal system memory / 128Mb internal user storage</li><li>Description: Niton XL3t XRF Analyzer</li><li>Detector Type: High-performance Semiconductor</li><li>Display Type: Adjustable angle, color, touch-screen display</li><li>Item Description: XL3t Analyzer; Portable</li><li>Height (English): 3.75 in.</li><li>Height (Metric): 95.5 mm</li><li>Length (English): 9.6 in.</li><li>Length (Metric): 244 mm</li><li>Width (English): 9.05 in.</li><li>Width (Metric): 230 mm</li><li>Optional Accessories:<ul><li>Portable test stand, stationary test stand, tripod stand;</li><li>Extenda-Pole™ extension pole;</li><li>Welding Mask;</li><li>HotFoot™ hot surface adapter;</li><li>Soil testing guard;</li><li>Internal CCD sample imaging system;</li><li>Variable spot size aperture</li></ul></li><li>Power Consumption: 100 µA</li><li>Security Features: Password-protected user security</li><li>Standard Accessories:<ul><li>Locking shielded carrying case, RFID reader, Shielded belt holster,</li><li>Two 4 (or optional 6) -cell lithium-ion battery packs,</li><li>Spare battery pack, 110/220 VAC battery charger/AC adaptor,</li><li>PC connection cables (USB and RS-232),</li><li>Niton Data Transfer (NDT™) PC software,</li><li>Safety lanyard, Check samples/standards</li></ul></li><li>Tube Type: Au anode 50kV maximum, 200µA maximum</li><li>Tube Voltage: 50 kV</li><li>Weight (English): 3 lb.</li><li>Weight (Metric): 1.3 kg</li><li>Voltage: 50 kV</li><li>Dimensions (L × W × H): 9.6 × 9.05 × 3.75 in. (244 × 230 × 95.5 mm)</li><li>Operating System: Ownership</li><li>Certifications/Compliance: CE, RoHS</li><li>Max. Power: 2W</li><li>Unit Size: Each</li></ul></div>

Thermo Scientific Niton DXL Precious Metal Analyzer

 Benchtop XRF analyzer for fast, non-destructive testing of gold and precious metals. Instantly identifies gold plating and provides karat value using Thermo Scientific™ AuDIT™ technology.

<div><div><div>Be absolutely sure of the value of the precious metals you buy and sell with a fast, simple nondestructive solution for gold analysis. Quickly distinguish between gold plating and solid gold and determine the accurate karat (K) weight of gold jewelry with the Thermo Scientific™ Niton™ DXL Precious Metal Analyzer.Designed specifically for countertop use in retail environments, the Niton DXL analyzer, with Thermo Scientific™ AuDIT™ gold-plating detection technology, delivers fast, reliable results for gold testing and metal analysis with just the push of a button.</div><div>Just a few seconds is all it takes to measure the exact precious metal content in jewelry, coins, and other valuable products using the Niton DXL Precious Metal Analyzer.</div></div><h3>⚙️ Features</h3><ul><li>Standard analytical range: 22 elements including all precious metals.</li><li>Nondestructive analysis with near instantaneous results.</li><li>Exceptionally fast, easy to use – see results in seconds on a bright, touch-screen color display.</li><li>No harsh chemicals or acids that can burn your fingers, ruin clothing, and damage countertops.</li><li>Easier, faster, more accurate than nitric acid test methods.</li><li>Faster, more comprehensive analysis than fire assay, with comparable accuracy.</li><li>Compact, elegant, ergonomic design for countertop placement in retail environments.</li><li>Measure the content of all gold and precious metals without manually changing the calibration.</li><li>Precisely determine the presence and concentration of other trace alloying elements and dangerous heavy elements, which could impact valuation and future refining needs.</li><li>Built-in CCD camera makes precise sample positioning effortless.</li><li>Optional small‑spot focus allows isolation and testing of small components.</li></ul></div><div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_DXL_Precious_Metal_Analyzer_6b9f367057.jpg" alt="Thermo Scientific™ Niton™ DXL Precious Metal Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_DXL_Precious_Metal_Analyzer_6b9f367057.jpg 156w," sizes="100vw" width="650" height="650"><h3>📏 Specifications</h3><ul><li>Applications: Non-destructive method to test the purity and chemistry of precious metals</li><li>Data Memory: 64MB internal system memory/128MB internal user storage</li><li>Data Storage: Internal &gt;10,000 readings with spectra</li><li>Data Transfer: USB</li><li>Description: Niton DXL Precious Metal Analyzer</li><li>Detector Type: High-performance Si-PIN semiconductor</li><li>Display Type: Color touch-screen display</li><li>Item Description: Niton DXL Precious Metal Analyzer</li><li>Height (English): 10.4 in.</li><li>Height (Metric): 265 mm</li><li>Length (English): 15.6 in.</li><li>Length (Metric): 396 mm</li><li>Width (English): 8.1 in.</li><li>Width (Metric): 206 mm</li><li>Length (English) Chamber: 6.9 in.</li><li>Length (Metric) Chamber: 172 mm</li><li>Height (English) Chamber: 5.2 in.</li><li>Height (Metric) Chamber: 133 mm</li><li>Width (English) Chamber: 7.2 in.</li><li>Width (Metric) Chamber: 184 mm</li><li>Optional Accessories:<ul><li>3mm small-spot focus feature</li><li>Additional battery pack</li><li>External battery charger</li><li>Locking shielded carrying case</li></ul></li><li>Power Consumption: 80µA</li><li>Security Features: Password-protected user security</li><li>Standard Accessories:&nbsp;<ul><li>One 7.2V 4-cell lithium-ion battery pack (charges in the instrument while on external power)</li><li>110/220V AC adapter; USB PC connection cable</li><li>Thermo Scientific™ Niton Data Transfer (NDT™) PC software</li><li>8mm measurement area; Internal CCD camera for precise sample positioning</li><li>Adhesive Tack for stabilization of samples</li><li>Spare puncture-resistant x-ray windows</li></ul></li><li>Tube Type: Ag anode 45kV maximum, 80µA maximum</li><li>Tube Voltage: 45 kV</li><li>Weight (English): 17 lb.</li><li>Weight (Metric): 7.7 kg</li><li>Voltage: 45 kV</li><li>System Electronics:<ul><li>400MHz ARM 11 CPU</li><li>300MHz dedicated DSP</li><li>80MHz ASICS DSP for signal processing</li><li>4096 channel MCA</li></ul></li><li>Data Entry: Touch-screen keyboard, user-programmable pick lists</li><li>Licensing: Varies by region. Contact your local distributor</li><li>Dimensions (L × W × H): 15.6 × 8.1 × 10.4 in. (396 × 206 × 265 mm)</li><li>Certifications/Compliance: CE, RoHS</li><li>Unit Size: Each</li></ul></div>

Thermo Scientific Niton XL2 Plus Handheld XRF Analyzer

Obtain fast, accurate elemental analysis for metal and alloy identification, PMI testing and more with the Niton™ XL2 Plus Handheld XRF Analyzer.

<div>Confidently perform elemental analysis with the Thermo Scientific™ Niton™ XL2 Plus handheld XRF analyzer. When durability, performance and productivity are top of mind, industrial businesses rely on the Niton XL2 Plus handheld XRF analyzer for fast results and low detection limits.&nbsp;Identify pure metals and alloys, or obtain geochemical data, the Niton XL2 Plus provides operators the ability to scan a broad range of materials in one versatile analyzer.</div>More than 75,000 Niton handheld XRF analyzers have been deployed worldwide since 1994, making them the trusted standard for in-field elemental analysis.<div><h3>⚙️ Features &amp; Benefits</h3><ul><li>2W X-Ray Tube</li><li>Silicon Drift Detector (SDD) for light element detection (Mg, Al, Si, P, S)</li><li>Detector ProGuard Protection</li><li>Micro Camera</li><li>Hot Swap Battery</li><li>Touch Screen and Directional Keys</li><li>Password Protected Security</li><li>IP54 Certified (Splash/ Dust Proof)</li><li>Nose Cone Alignment Guides</li></ul><h3>🧪 Applications</h3><ul><li>Verification of metals and alloys in manufacturing</li><li>Quality Assurance testing for positive material identification</li><li>Point-and-shoot sorting at scrap recycling operations</li><li>Coating thickness measurements from single element layers</li><li>Precious metal assay of bullion and jewelry</li><li>Geochemical analysis for ore trading and grade control</li><li>On-site heavy metal screening of polluted soils</li><li>Lead in paint inspection of industrial facilities</li><li>Screening of hazardous substances in consumer goods</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_2_Plus_Handheld_XRF_Analyzer_3_cb63ae77a5.jpg" alt="Thermo Scientific™ Niton™ XL2 Plus Handheld XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_2_Plus_Handheld_XRF_Analyzer_3_cb63ae77a5.jpg 156w," sizes="100vw" width="650" height="650"><h3>📏 Specifications</h3><ul><li>Analytical Range: Mg–U</li><li>Available Analytical Modes: General Metals, Precious Metals, Coatings, Mining, Soils, Electronic Alloys, Plastics, Industrial Lead in Paint, Lead in Paint Products</li><li>Bluetooth: Supports print functionality, external GPS connectivity and barcode reader</li><li>Camera: Integrated CCD micro camera for locating and recording measurement positions</li><li>Certifications/Compliance: CE, RoHS, FCC, Industry Canada, Safety to IEC 61010-1, UL 61010-1, IP54 (splash and dust proof)</li><li>Data Entry:&nbsp;<ul><li>Touchscreen keyboard</li><li>User customizable data entry</li><li>Optional wireless remote barcode reader</li></ul></li><li>Data Storage:<ul><li>64 MB internal system memory / 128 MB internal user storage</li><li>Stores approximately 10,000 readings with spectra (fewer if images are saved)</li></ul></li><li>Data Transfer: USB, Bluetooth, RS-232 serial communication</li><li>Description: Niton XL2 Plus Handheld XRF Analyzer</li><li>Dimensions (L × W × H): 10 × 10.8 × 3.9 in (25.6 × 27.5 × 10 cm)</li><li>Display Type: Fixed angle, color, resistive touchscreen display</li><li>Global Positioning System: Optional external GPS (via Bluetooth)</li><li>Languages: English, Chinese, Spanish, Portuguese, Russian, Japanese, German, Korean, French, Italian, Czech</li><li>Libraries:&nbsp;<ul><li>Default alloy libraries based on SAE, AISI, ASTM, AA standards</li><li>Users may create and edit libraries</li></ul></li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Operating Environment:<ul><li>Temperature: -10 °C to 50 °C</li><li>Humidity: 0% to 80% relative humidity non-condensing</li></ul></li><li>Operating System: Proprietary</li><li>Optional Accessories:<ul><li>Thermo Scientific™ portable test stand</li><li>Thermo Scientific™ mobile test stand</li><li>Thermo Scientific™ field mate test stand</li><li>Thermo Scientific™ soil guard</li></ul></li><li>Power Consumption:<ul><li>7.4V lithium-ion battery, or 12V DC, 3A, 36W power supply</li><li>Hot swap functionality keeps analyzer powered during battery replacements</li></ul></li><li>Security Features: Password-protected user security</li><li>Software: Support Software: Niton Data Transfer (NDT) PC software</li><li>Spot Size: 8 mm collimation</li><li>Standard Accessories:<ul><li>Locking shielded carrying case</li><li>Two (2) lithium-ion battery packs</li><li>One (1) 110/220 VAC battery charger/ AC adaptor</li><li>Check samples</li><li>Belt holster</li><li>Safety lanyard</li><li>PC connection cables (USB and RS-232)</li></ul></li><li>System Details: Built-in standardization via automatic system check</li><li>Weight (English): 3.4 lbs with battery</li><li>Weight (Metric): 1.53 kg with battery</li><li>X-Ray Source Type:<ul><li>X-Ray Tube: Ag anode (6–45 kV, 1–200 µA, 2W max)</li><li>Dynamically adjustable current for optimal sensitivity on every analysis</li></ul></li><li>Applications: Identify pure metals and alloys, detect tramp elements, or obtain geochemical data</li><li>Detector Type:&nbsp;<ul><li>Silicon Drift Detector (SDD)</li><li>Detector ProGuard protection included</li></ul></li><li>Tube Voltage: 6 to 45 kV</li><li>Unit Size: Each</li></ul><h3>Which analyzer for your application?</h3><figure class="image"><img style="aspect-ratio:1024/1102;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></figure><blockquote><h3>Helpful links</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-selection-guide.html">Which XRF analyzer is right for me?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-rental-leasing.html">Should I rent or lease this product?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/xrf-radiation-safety-training.html">Where can I get radiation safety training?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/spectroscopy-elemental-isotope-analysis-learning-center/elemental-analysis-information/xrf-technology.html">What is XRF Technology?</a></li><li>What are the applications for this handheld XRF analyzer?<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-scrap-metal-recycling-analysis.html">Scrap Metal Recycling</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-manufacturing-metal-fabrication-analysis.html">Manufacturing and Metal Fabrication</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/positive-material-identification-oil-gas.html">Positive Material Identification</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-mining-exploration-solutions.html">Mining and Exploration</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-precious-metals-jewelry-analysis.html">Precious Metals</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-consumer-safety-regulatory-solutions.html">Consumer Safety &amp; Regulatory</a></li></ul></li></ul></blockquote></div>

Thermo Scientific Niton XL3t GOLDD+ XRF Analyzer

High-performance handheld XRF analyzer with GOLDD™ technology for fast, accurate analysis of metals, light elements, ores, soils and contaminants – no helium or vacuum needed.

<div><div><div>Industries from mining and exploration to scrap metal recycling depend on fast, accurate elemental analysis. The Thermo Scientific™ Niton™ XL3t GOLDD+ XRF Analyzer provides reliable, real-time data for sample identification and positive material identification for even difficult-to-analyze light elements, without helium purging or vacuum pumps.&nbsp;The Niton XL3t GOLDD+ Analyzer delivers a feature-rich package enhanced with Geometrically Optimized Large Area Drift Detector (GOLDD™) technology for improved light element (Mg-S) analysis, the lowest limits of detection and fastest measurement times.</div><div><h3>⚡ Performance:</h3>GOLDD Technology:&nbsp;When low detection limits and high sample throughput are critical, the Niton XL3t GOLDD+ XRF analyzer delivers measurement times up to 10-times faster than conventional Si-PIN detectors and up to 3-times more precise than conventional smaller silicon drift detectors (SDD) - without helium purge or vacuum. For further enhancing light element analysis, a helium purge option is available. Niton analyzers also feature the highest performance X-ray tube and speed detector available on the market.<h3>🧪 Wide Range of Applications:</h3><ul><li>Scrap Metal Recycling:&nbsp;<ul><li>Sorts aluminum, titanium and bronze alloys, and achieves superior performance for tramp and trace element analysis.</li></ul></li><li>Mining Exploration:&nbsp;<ul><li>Fast, accurate analysis of light elements.&nbsp;</li><li>Identifies anomalies near the averages naturally found in the earth's crust.&nbsp;</li><li>Facilitates advanced exploration and soil analysis, concentrate measurement, ore blending, precious metal identification and lab analysis prequalification.</li></ul></li><li>Environmental:&nbsp;<ul><li>Detects contaminants such as chlorine and sulfur in sediment and arsenic in soil.&nbsp;</li><li>Identifies environmental hazards in residential, commercial and industrial settings, such as toxic drywall.</li></ul></li></ul></div></div><h3>⚙️ Features</h3><ul><li>Standard analytical range: Up to 30 elements from Mg to U (varies by application).</li><li>Most powerful x-ray tube on the market for handheld XRF analysis.</li><li>Point and shoot simplicity- very easy to use even by nontechnical personnel.</li><li>Rugged design for real-world industrial environments.</li><li>Nondestructive analysis with near instantaneous results.</li><li>Sealed against moisture and dust.</li><li>Ergonomically designed.</li><li>Daylight-readable icons.</li><li>Incorporates multi-language options.</li><li>Color, touch-screen display.</li></ul></div><div><h3>🔗 Connectivity</h3><ul><li>Integrated USB and Bluetooth™ communications provide direct data transfer to your PC or networked storage device. &nbsp;</li><li>Standard Thermo Scientific™ Niton Data Transfer (NDT™) PC software allows you to: &nbsp;<ul><li>Set operator permissions &nbsp;</li><li>Generate custom reports &nbsp;</li><li>Print certificates of analysis &nbsp;</li><li>Remotely monitor and control the instrument from your PC &nbsp;</li></ul></li><li>Optional accessories: Bluetooth barcode reader, Bluetooth printer, Bluetooth GPS</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_3t_GOLDD_XRF_Analyzer_5_9e51a6a9ac.jpg" alt="Thermo Scientific™ Niton™ XL3t GOLDD+ XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_3t_GOLDD_XRF_Analyzer_5_9e51a6a9ac.jpg 219w," sizes="100vw" width="650" height="464"><h3>📏 Specifications</h3><ul><li>Analytical Range: Up to 30 elements from Mg to U (varies by application)</li><li>Available Analytical Modes: Varies by application<ul><li>Alloy Modes: Metal Alloy, Electronics Alloy, Precious Metals</li><li>Bulk Modes: Soil, Mining, TestAll</li><li>Plastic Modes: RoHS Plastics, Toy and Consumer Goods, Plastics, TestAll, Painted Products</li><li>Custom Modes: Upon request</li></ul></li><li>Certifications/Compliance: CE, RoHS</li><li>Data Entry: Touch-screen keyboard, user-programmable pick lists, optional wireless remote barcode reader</li><li>Data Memory: 32MB internal system memory / 128 MB internal user storage</li><li>Data Storage: Internal &gt;10,000 readings with spectra</li><li>Data Transfer: USB, Bluetooth and RS-232 serial communication</li><li>Description: Niton XL3t GOLDD+ XRF Analyzer</li><li>Dimensions (L × W × H): 9.6 × 9.05 × 3.75 in. (244 × 230 × 95.5 mm)</li><li>Display Type: Tilting, color, touch-screen display</li><li>Height (English): 3.75 in.</li><li>Height (Metric): 95.5 mm</li><li>Item Description: XL3t GOLDD+ XRF Analyzer</li><li>Length (English): 9.6 in.</li><li>Length (Metric): 244 mm</li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Max. Power: 2W</li><li>Operating System: Ownership</li><li>Optional Accessories:<ul><li>3mm small-spot collimation</li><li>Portable test stand</li><li>Stationary (benchtop) test stand</li><li>Mobile test stand</li><li>Field Mate</li><li>Thermo Scientific™ Extend-a-Pole™</li><li>Welding mask</li><li>Thermo Scientific™ HotFoot™ hot surface adapter</li><li>Soil testing guard</li></ul></li><li>Power Consumption: 0 to 200 μA</li><li>Security Features: Password-protected user security</li><li>Standard Accessories:<ul><li>Integrated CCD camera for locating and storing images</li><li>Locking shielded carrying case</li><li>Shielded belt holster</li><li>Two lithium-ion battery packs</li><li>Spare battery pack</li><li>110/220 VAC battery charger/AC adaptor</li><li>PC connection cables (USB and RS-232)</li><li>Thermo Scientific™ Niton Data Transfer (NDT™) PC software</li><li>Safety lanyard</li><li>Check samples/standards</li></ul></li><li>System Electronics: 533 MHz ARM 11 CPU, 300 MHz dedicated DSP, 80 MHz ASICS DSP for signal processing</li><li>Tube Type: Ag anode 50 kV and 200 μA</li><li>Voltage: 6 to 50 kV</li><li>Weight (English): 3 lb.</li><li>Weight (Metric): 1.3 kg</li><li>Width (English): 9.05 in.</li><li>Width (Metric): 230 mm</li><li>Applications: Sample Identification, Positive Material Identification</li><li>Detector Type: Geometrically Optimized Large Area Drift Detector</li><li>Tube Voltage: 6 to 50 kV</li><li>Unit Size: Each</li></ul><h3>Which analyzer for your application?</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></div>

Thermo Scientific Niton XL2 100G General Metal Analyzer

Get immediate, nondestructive elemental analysis of alloy materials from titanium to nickel with the Thermo Scientific™ Niton™ XL2 100G General Metal Analyzer. 

<div><div><div><div><div>Get immediate, nondestructive elemental analysis of alloy materials from titanium to nickel with the Thermo Scientific™ Niton™ XL2 100G General Metal Analyzer. The XL2 100G analyzer is a practical, cost-effective solution that offers fast analysis for general alloy identification, basic fabrication, and scrap metal sorting.&nbsp;This high value, high performance analyzer features advanced electronics yet it is ruggedly built to withstand the harshest environments, in the field or on the shop floor.</div><div><h3>The value choice to ensure accuracy, precision, and ease of use:</h3><ul><li>Precise elemental analysis of alloy materials</li><li>Very easy to use – even by non-technical personnel</li><li>Ruggedly designed for the most challenging industrial environments, and sealed against moisture and dust</li><li>Completely nondestructive test</li><li>Ergonomically designed&nbsp;</li><li>Customizable menus with multiple language options and daylight-readable icons</li><li>Standard analytical range of more than 25 elements from sulfur to uranium.</li></ul></div></div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_2_100_G_General_Metal_Analyzer_340e83faa3.jpg" alt="Thermo Scientific™ Niton™ XL2 100G General Metal Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_2_100_G_General_Metal_Analyzer_340e83faa3.jpg 156w," sizes="100vw" width="650" height="650"><h3>Specifications</h3><ul><li>Analytical Range: 25 elements from Ti to Bi</li><li>Available Analytical Modes: Alloy Modes: Metal Alloy</li><li>Certifications/Compliance: CE, RoHS</li><li>Data Entry:&nbsp;<ul><li>Touch-screen keyboard</li><li>User-programmable pick lists</li><li>Optional wireless remote barcode reader</li></ul></li><li>Data Storage: Internal &gt;10,000 readings with spectra</li><li>Data Transfer: USB, Bluetooth™, and RS-232 serial communication</li><li>Dimensions (L x W x H): 10.25 × 11 × 4 in. (256 × 275 × 100 mm)</li><li>Display Type: Fixed angle, color, touch-screen display</li><li>IP Rating: IP54 (splash and dust proof)</li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Max. Power: 2W</li><li>Operating System: Ownership</li><li>Optional Accessories:&nbsp;<ul><li>Thermo Scientific™ portable test stand</li><li>Stationary (bench-top) stand</li><li>Mobile test stand</li></ul></li><li>Security Features: Password-protected user security</li><li>Standard Accessories:&nbsp;<ul><li>Locking shielded carrying case</li><li>Shielded belt holster</li><li>One 6-cell Li-ion battery pack</li><li>110/220 VAC battery charger/AC adaptor</li><li>PC connection cables (USB and RS-232)</li><li>Niton Data Transfer (NDT) PC software</li><li>Safety lanyard</li><li>Check samples/standards</li></ul></li><li>System Electronics:&nbsp;<ul><li>400 MHz ARM 11 CPU</li><li>300 MHz dedicated DSP</li><li>80 MHz ASICS DSP for signal processing</li><li>4096 channel MCA</li><li>64 MB internal system memory / 128 MB internal user storage</li></ul></li><li>Tube Type: Ag anode 38kV maximum, 80 μA maximum</li><li>Weight (English): 3 lbs 5.8 oz</li><li>Weight (Metric): 1.53 kg</li><li>Applications: Elemental Analysis</li><li>Detector Type: High-performance Semiconductor</li><li>Tube Voltage: 38 kV</li><li>Unit Size: Each</li></ul><h3>Which analyzer for your application?</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></div></div></div>

Thermo Scientific Niton XL2 XRF Precious Metal Analyzer

The Thermo Scientific™ Niton™ XL2 XRF Precious Metal Analyzer provides a fast, accurate, and most importantly, nondestructive method to test the purity and chemistry of all precious metals. 

<div><div><div><div><div>With the volatility and high price of gold, failing to detect just a small variation in composition can be an expensive mistake. The Thermo Scientific™ Niton™ XL2 XRF Precious Metal Analyzer provides a fast, accurate, and most importantly, nondestructive method to test the purity and chemistry of all precious metals.&nbsp;The Niton XL2 XRF Precious Metal Analyzer quickly detects gold plating and counterfeit gold and gives you the exact elemental composition of jewelry and coins so you can be absolutely certain of the value of the precious metals you buy and sell.</div><div>The Niton XL2 XRF Precious Metal Analyzer delivers accurate analysis in just seconds in an easy-to-use, robust and reliable package. Measure the content of all gold and precious metals with no need to manually change your calibration based on the metal you're analyzing—e.g., gold (Au), silver (Ag), platinum (Pt), palladium (Pd).<ul><li>Easier, faster and more accurate than nitric acid test methods.</li><li>Faster, more comprehensive analysis than fire assay with comparable accuracy.</li><li>Efficiently identify most gold-plated items with Thermo Scientific AuDIT™ gold-plating detection technology.</li><li>Precisely determine the presence and concentration of other trace alloying elements and dangerous heavy elements, which could impact valuation and future refining needs.</li></ul><h3>⚙️ Features</h3><ul><li>Standard analytical range: 22 elements from S to U (varies by application).</li><li>Point and shoot simplicity—very easy to use even by nontechnical personnel.</li><li>Ideally suited for retail environments.</li><li>Nondestructive analysis with near-instantaneous results.</li><li>Ergonomic design.</li></ul></div></div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_2_XRF_Precious_Metal_Analyzer_6d4f6473b2.jpg" alt="Thermo Scientific™ Niton™ XL2 XRF Precious Metal Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_2_XRF_Precious_Metal_Analyzer_6d4f6473b2.jpg 144w," sizes="100vw" width="650" height="706"><h3>📏 Specifications</h3><ul><li>Applications: Non-destructive method to test the purity and chemistry of precious metals</li><li>Available Analytical Modes: Varies by application<ul><li>Alloy modes: metal alloy, electronics alloy, precious metals.&nbsp;</li><li>Bulk modes: mining, soil.&nbsp;</li><li>Plastic modes: RoHS plastics, toy and consumer goods plastics, Thermo Scientific TestAll, painted products.&nbsp;</li><li>Custom modes: upon request</li></ul></li><li>Data Memory: 64MB internal system memory / 128MB internal user storage</li><li>Data Storage: Internal &gt;10,000 readings with spectra</li><li>Data Transfer: USB, Bluetooth and RS-232 serial communication</li><li>Description: Niton XL2 XRF Precious Metal Analyzer</li><li>Detector Type: High-performance Semiconductor</li><li>Display Type: Fixed angle, color, touch-screen display</li><li>Height (English): 4 in.</li><li>Height (Metric): 100 mm</li><li>Length (English): 10.25 in.</li><li>Length (Metric): 256 mm</li><li>Width (English): 11 in.</li><li>Width (Metric): 275 mm</li><li>Optional Accessories:&nbsp;<ul><li>Portable test stand</li><li>Stationary (bench-top) stand</li><li>Mobile test stand</li><li>Welding mask</li><li>Soil testing guard</li></ul></li><li>Power Consumption: 100μA</li><li>Security Features: Password-protected user security</li><li>Standard Accessories:&nbsp;<ul><li>Locking shielded carrying case</li><li>Shielded belt holster</li><li>Two 6-cell lithium-ion battery packs</li><li>110/220VAC battery charger/AC adaptor</li><li>PC connection cables (USB and RS-232)</li><li>Thermo Scientific™ Niton Data Transfer (NDT™) PC software</li><li>Safety lanyard</li><li>Check samples/standards</li></ul></li><li>System Details:&nbsp;<ul><li>4096 channel MCA</li><li>64MB internal system memory / 128MB internal user storage</li></ul></li><li>Tube Type: Ag anode 45 kV maximum, 80μA maximum</li><li>Tube Voltage: 45 kV</li><li>Weight (English): 3.0 lb., 5.8 oz.</li><li>Weight (Metric): 1.53 kg</li><li>System Electronics:&nbsp;<ul><li>400 MHz ARM 11 CPU</li><li>300 MHz dedicated DSP</li><li>80 MHz ASICS DSP for signal processing</li></ul></li><li>Data Entry: Touch-screen keyboard, user-programmable pick lists, optional wireless remote barcode reader</li><li>Licensing: Registration: Varies by region. Contact your local distributor.</li><li>Dimensions (L × W × H): 10.25 × 11 × 4 in. (256 × 275 × 100 mm)</li><li>Operating System: Ownership</li><li>Certifications/Compliance: CE, RoHS</li><li>IP Rating: IP54 (splash and dust proof)</li><li>Max. Power: 2W</li><li>Unit Size: Each</li></ul></div></div></div>

Thermo Scientific Niton Apollo Handheld LIBS Analyzer

High-performance handheld LIBS analyzer for fast, reliable carbon analysis. Ideal for L/H grade steels and alloy verification with maximum mobility and on-site productivity.

Confidently perform elemental analysis with the Thermo Scientific™ Niton™ Apollo™ handheld LIBS analyzer. When carbon detection and mobility are top of mind, industrial businesses rely on the Niton Apollo analyzer for excellent performance and enhanced productivity.&nbsp;Identify low alloy/carbon steels and L and H grade steels. This analyzer transforms a traditional cart-mounted optical emission spectroscopy (OES) system into a highly portable, easy-to-use handheld analyzer.<div><h3>⚙️ Features &amp; Benefits</h3><ul><li>1064nm laser</li><li>WiFi enabled</li><li>Macro and micro cameras</li><li>Hot swap battery (Milwaukee Tool™ compatible)</li><li>Tilting, color touchscreen</li><li>Directional keys</li><li>Chamber pressure, spectral type, light/dark sensor safety interlocks</li><li>Password protected security</li><li>IP54 certified (splash/dust proof)</li><li>Reduced aperture &amp; compact tapered-nose design</li></ul><h3>🧪 Applications</h3><ul><li>Determine alloy composition and grade for a wide range of metallurgical samples</li><li>Calculate carbon equivalency to determine piping weldability</li><li>Verify critical assets, such as, piping, valves and reaction vessels for Positive Material Identification (PMI)</li><li>Inspect materials at receiving, in-process fabrication and outgoing Quality Control (QC)</li><li>Qualify Material Test Reports (MTR)</li><li>Prevent contaminated scrap from entering the supply stream</li><li>Detect tramp and trace elements to meet regulatory standards</li><li>Enhance productivity by measuring challenging structural shapes and sizes, including 1/4" piping, 1/4" bars, and larger weld wires</li><li>Maximize efficiency and bypass additional costs and time spent with on-site small-part measurement capabilities</li><li>Obtain unprecedented precision with a refined tapered nose and Argon seal, increasing shots per cylinder and return on investment</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_Apollo_Handheld_LIBS_Analyzer_5951f75476.jpg" alt="Thermo Scientific™ Niton™ Apollo™ Handheld LIBS Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_Apollo_Handheld_LIBS_Analyzer_5951f75476.jpg 156w," sizes="100vw" width="650" height="650"><h3>📏 Specifications</h3><ul><li>Analytical Range: C, Al, Si, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Nb, Mo, W</li><li>Argon Usage:&nbsp;<ul><li>High purity argon purge</li><li>About 200 shots per cartridge</li></ul></li><li>Available Analytical Modes: Stainless steel mode, Low alloy/carbon steel mode</li><li>Bluetooth: Bluetooth™ 4.0 (supports print functionality)</li><li>Camera:&nbsp;<ul><li>Integrated CCD macro camera for capturing overview images of parts and tagging measurement locations</li><li>Integrated CCD micro camera for locating and recording measurement positions</li></ul></li><li>Certifications/Compliance:&nbsp;<ul><li>Certifications: IP54 certified (splash and dust proof)</li><li>Compliance: CE, RoHS, FCC, Industry Canada, Safety to IEC 61010-1:2010</li></ul></li><li>Data Entry: Touchscreen keyboard User customizable data entry</li><li>Data Storage:&nbsp;<ul><li>512 MB internal system memory / 16 GB industrial grade storage</li><li>Stores approximately 5,000 readings with spectra (fewer if macro and micro images are saved)</li></ul></li><li>Data Transfer: WiFi, USB</li><li>Description: Niton Apollo Handheld LIBS Analyzer</li><li>Dimensions (L × W × H): 12 x 13 x 4 in (30.48 x 33.02 x 10.16 cm)</li><li>Display Type: Tilting, color, resistive touchscreen display</li><li>Global Positioning System: Internal GPS (ability to include coordinates with sample information)</li><li>Languages: English</li><li>Laser: 1064nm</li><li>Libraries:&nbsp;<ul><li>Default alloy libraries based on SAE, AISI, ASTM, AA, DIN, GB standards,&nbsp;</li><li>Users may create, clone and edit libraries</li></ul></li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Operating Environment: Temperature: 32°F - 104°F (0°C - 40°C)</li><li>Operating System: Linux™</li><li>Optional Accessories:&nbsp;<ul><li>Thermo Scientific™ bulk argon adapter</li><li>Additional laser safety glasses</li></ul></li><li>Power Consumption: 24V, 3.75A, 90W power supply, Milwaukee Tool™ battery pack Hot swap functionality keeps analyzer powered during battery replacements</li><li>Safety Features: Chamber pressure, spectral type, light/dark sensor interlocks</li><li>Software: NitonConnect PC software</li><li>Standard Accessories:&nbsp;<ul><li>Locking shielded carrying case</li><li>Two (2) Milwaukee M18™ Redlithium™ High Demand™ CP2.0 battery packs</li><li>One (1) Milwaukee M18™ &amp; M12™ multi-voltage charger</li><li>Five (5) Thermo Scientific™ analytical argon cartridges</li><li>Setup standards</li><li>Laser safety glasses</li><li>Instrument cleaning kit</li><li>Safety lanyard and carabiner</li><li>PC connection cable</li></ul></li><li>Weight (English): 6.4 lbs with battery</li><li>Weight (Metric): 2.9 kg with battery</li><li>Applications: Identify low alloy/carbon, L grade, and H grade steels</li><li>Unit Size: Each</li></ul><blockquote><h3>Helpful links</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-selection-guide.html">Which Niton analyzer is right for me?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-rental-leasing.html">Should I rent or lease this product?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/xrf-radiation-safety-training.html">Where can I get laser safety training?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/industrial-elemental-radiation-solutions/how-does-libs-work.html">How does LIBS work?</a></li><li>What are the applications for this handheld LIBS analyzer?<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/positive-material-identification-oil-gas.html">Positive Material Identification</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-manufacturing-metal-fabrication-analysis.html">Manufacturing and Metal Fabrication</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-scrap-metal-recycling-analysis.html">Scrap Metal Recycling</a></li></ul></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/industrial-elemental-radiation-solutions/niton-apollo-handheld-libs-analyzer-faqs.html">I have additional LIBS questions, where can I learn more?</a></li></ul></blockquote></div>

Thermo Scientific ARL 9900 Total Cement Analyzer

Combines XRF and XRD in one instrument for fast and precise analysis of cement materials. One sample, one analysis – full chemical and phase information.

Achieve excellent process control and save fuel in your cement plant with both chemical and phase analysis in one simple operation. The Thermo Scientific™ ARL™ 9900 Total Cement Analyzer combines X-Ray Fluorescence (XRF) and X-Ray Diffraction (XRD) technologies for a more complete characterization of any given crystalline sample.&nbsp;Various compounds can be controlled like quartz in raw meal, hot meal, free lime in clinker, clinker phases, and additions in cement (e.g. limestone, GBFS, pozzolan) or even clinker content in cement. Clinker phase analysis ensures consistent clinker quality, which is the key to high-performance concrete.The ARL 9900 Total Cement Analyzer provides fast process monitoring during the critical phases of cement manufacturing. It combines:<ul><li>XRF analysis – determines elemental composition</li><li>XRD analysis – provides mineralogical information</li></ul>Together, they ensure the integrity of the final product.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_9900_Intelli_Power_Series_3_75f234904f.jpg" alt="Thermo Scientific™ ARL™ 9900 Total Cement Analyzer: Integration of XRF and XRD in the same instrument: one sample, one instrument, one analysis for two techniques." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_9900_Intelli_Power_Series_3_75f234904f.jpg 237w," sizes="100vw" width="1143" height="753">Traditionally, both analyses required two separate X-ray instruments, leading to higher costs. Thanks to the compact integrated XRD system, both techniques are now included in one instrument, offering key benefits:<ul><li>Only one sample introduction – fast, simple, reliable</li><li>Single user interface for both techniques</li><li>Combined elemental and phase results in one report</li><li>Minimized floor space</li><li>Replaces two instruments</li><li>Rapid and precise analysis of solid samples</li></ul>IntelliPower: choose power level as needed – 1200W, 2500W, 3600W or 4200W Advanced software: instant result reporting after analysis Easy upgrades for future analytical needs<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_9900_Total_Cement_Analyzer_8c67ede30b.jpg" alt="Thermo Scientific™ ARL™ 9900 Total Cement Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_9900_Total_Cement_Analyzer_8c67ede30b.jpg 165w," sizes="100vw" width="1626" height="1536"><h3>X-ray System</h3><ul><li>X-ray tube mounted above the sample – prevents damage (e.g. from fragile pellets)</li><li>Thermostatically regulated spectrometer – precise, sensitive, and stable measurements</li></ul><h3>Fixed Monochromators</h3><ul><li>Compact slit-crystal geometry – detects trace elements</li><li>Simultaneous multi-element analysis – for faster response</li></ul><h3>XRF Goniometers</h3><ul><li>Programmable for quantitative or qualitative element analysis</li><li>High-speed sequential X-ray spectrometry using Moire fringe technology</li><li>Handles nonroutine element analysis</li></ul><h3>Automation</h3><ul><li>Fast and reliable sample introduction, variable automation levels</li><li>Can be linked to automatic sample prep systems for online process control</li></ul>

Thermo Scientific™ ARL™ SMS-XY Automation for XRF

The Thermo Scientific™ ARL™ SMS-XY XRF system enables unattended operation, sample prep and analysis with high quality, efficiency, and reduced cost.

<div><div><h4>Increase your capacity to handle more samples in less time.&nbsp;</h4>The Thermo Scientific™ ARL™ SMS-XY Automation for XRF permits continuous and unattended operation of<a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?instrumentationItems=100&amp;manufacturerItems=3&amp;search=9900"> Thermo Scientific™ ARL™ 9900 series X-ray Spectrometers</a>. Increased automation brings:&nbsp;<ul><li>Higher analysis quality</li><li>Lower analysis costs</li><li>Sustainable analysis cadence with predictable and reproducible response times</li><li>Short payback period</li></ul><h3>Automated Sample Handling</h3>The Thermo Scientific™ ARL™ OEM-XY automated sample loader allows connecting the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1211">ARL™ PERFORM'X</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products?instrumentationItems=100&amp;manufacturerItems=3&amp;search=9900">ARL™ 9900</a> series to fully automatic preparation machines. Key features:<ul><li>Prepared samples (usually pressed pellets) are transported via belt conveyor from press to spectrometer</li><li>Unattended operation is ensured by engineering software supervision</li><li>Suitable for cement, metallurgy, and mining applications</li></ul></div><div><h3>Complete Automation with ARL SMS Software</h3>The ARL SMS software provides full automation of Thermo Scientific™ XRF spectrometers for routine production control, including sample preparation and analysis.<h3>Key Benefits:</h3><ul><li>Regular analysis of control samples with SPC evaluation for anomaly detection</li><li>Online connectivity for automatic sample preparation</li><li>Supports up to two sample transfer systems</li><li>Allows manual or online registration of externally prepared samples</li><li>Available as turnkey solution in ARL™ QuantoShelter cabin for production floor deployment</li><li>Seamless integration into quality control and production processes</li><li>Automatic result transmission after analysis</li></ul><h3>Compatible Sample Types:</h3><ul><li>Metallic samples (ferrous and non-ferrous)</li><li>Oxides from metal production (ores, sinters, baths, slags, blast furnace slags)</li><li>Oxides from minerals and cement</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_SMS_XY_Automation_for_XRF_2_8bce1d83a2.jpg" alt="Thermo Scientific™ ARL™ SMS-XY Automation for XRF" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_SMS_XY_Automation_for_XRF_2_8bce1d83a2.jpg 179w," sizes="100vw" width="650" height="569"></div></div>

Thermo Scientific ARL SMS-Omega XRF Instrument

Boost production efficiency with fully automated XRF analysis. The ARL OPTIM'X with SMS-Omega ensures high-quality results with unattended prep, rapid WDXRF, and compact design.

Keep up with production demands with automated XRF analysis. When different types of material have to be processed in parallel, the <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1212">Thermo Scientific™ ARL OPTIM'X™ WDXRF Spectrometer</a> with the Thermo Scientific™ ARL™ SMS-Omega XRF Instrument is the solution. Automatic sample preparation and handling without user intervention, combined with rapid analysis, provide high-quality results. This innovative solution has a compact footprint of less than 1 m², so it can be installed in centralized laboratories or on production shop floors, wherever fully automated industrial production control is needed.This cost-effective system is a unique combination of Thermo Scientific XRF and automation technology for fully automated sample preparation and analysis of one material type.<h3>Main Features</h3><ul><li>Unattended instrument monitoring and integrated audit trail functions</li><li>Sample handling arm equipped with a suction device (metals version) or a gripper (oxide version) loads samples for analysis.</li><li>Samples processed under strict identical and reproducible conditions</li><li>Fixed circular magazine</li><li>XRF functionality provided by the flexible and compact <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/products/1212">Thermo Scientific™ ARL™ OPTIM'X WDXRF </a>Instrument</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_SMS_Omega_XRF_Instrument_2_ee38dccfef.jpg" alt="Thermo Scientific™ ARL™ SMS-Omega XRF Instrument " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_SMS_Omega_XRF_Instrument_2_ee38dccfef.jpg 233w," sizes="100vw" width="650" height="435"><h3>Features of the OPTIM'X WDXRF Instrument</h3><ul><li>WDXRF platform with sequential and/or simultaneous capabilities</li><li>Configurable to cover all elements from fluorine (F) to uranium (U) in sequential mode</li><li>Fast analysis of solids, liquids and loose powders with superior spectral resolution</li><li>No water cooling or gas supply required (depending on configuration)</li><li>Closely coupled optics for increased intensity (50% higher than conventional geometry)</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_OPTIM_X_WDXRF_Spectrometer_b264a3a303.jpg" alt="Thermo Scientific™ ARL™ OPTIM'X WDXRF Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_OPTIM_X_WDXRF_Spectrometer_b264a3a303.jpg 94w," sizes="100vw" width="650" height="1077"><h3>Features of the Fixed Circular Magazine</h3><ul><li>Eight positions for storing reference standards</li><li>Allows occasional manual introduction of prepared samples</li><li>One additional position dedicated to filing production samples following analysis</li><li>The complete system can also be supplied within a Thermo Scientific™ ARL™ QuantoShelter container for in situ analysis closer to the process.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_SMS_Omega_XRF_Instrument_87d53e64fb.jpg" alt="Thermo Scientific™ ARL™ SMS-Omega XRF Instrument" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_SMS_Omega_XRF_Instrument_87d53e64fb.jpg 216w," sizes="100vw" width="650" height="471">

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