<p><strong>Post-translational modifications (PTMs) are where so much of biology’s complexity lives, but they are also some of the hardest molecular features to analyze with confidence. Phosphorylation, asymmetric dimethylarginine (ADMA), and O-GlcNAcylation (O-GlcNAc) often occur at low abundance, can be highly labile, and frequently require precise site localization to understand their biological meaning. This</strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/tn_004377_ov_phosphorylation_ptm_etd_excedion_pro_tn004377_na_en_71f681655f.pdf"><strong> technical note </strong></a><strong>shows how the </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1958"><strong>Thermo Scientific Orbitrap Excedion Pro Hybrid Mass Spectrometer</strong></a><strong> helps address those challenges by combining fast, sensitive performance with complementary </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/7217"><strong>HCD and EThcD fragmentation</strong></a><strong> workflows.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Phosphorylation_ADMA_and_O_Glc_N_Ac_Analysis_on_the_Orbitrap_Excedion_Pro_Mass_Spectrometer_d24a5de98e.jpg" alt="Thermo Fisher Scientific: Phosphorylation, ADMA, and O-GlcNAc Analysis on the Orbitrap Excedion Pro Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Phosphorylation_ADMA_and_O_Glc_N_Ac_Analysis_on_the_Orbitrap_Excedion_Pro_Mass_Spectrometer_d24a5de98e.jpg 245w," sizes="100vw" width="1024" height="512"></p><p>Using enriched PTM samples and automated data-dependent acquisition, the study demonstrates that the <strong>Orbitrap Excedion Pro MS</strong> can deliver both depth and confidence across multiple PTM classes. For phosphorylation analysis, the platform identified 5,892 unique phosphosites from IMAC-enriched samples and <strong>2,941 </strong>unique phosphotyrosine sites after phosphotyrosine enrichment, highlighting strong performance for both broad and highly targeted signaling studies. Just as importantly, the data show that HCD and EThcD provide complementary value, with each fragmentation method contributing unique site identifications and helping resolve ambiguous assignments.</p><p>The note also highlights the value of EThcD for more analytically demanding PTMs. In ADMA-enriched samples, EThcD delivered more ADMA peptide-spectrum matches and more unique modified peptides than HCD, supporting improved confidence in site characterization. For O-glycopeptides, the Orbitrap Excedion Pro MS uses an intelligent HCD-product-dependent-EThcD strategy that triggers EThcD only when oxonium ions are detected, improving productivity while preserving the fragmentation detail needed for confident glycosite localization.</p><p>Overall, this technical note shows how <strong>Orbitrap Excedion Pro MS </strong>enables researchers to go deeper into PTM biology with greater sensitivity, better site confidence, and smarter acquisition. For scientists studying signaling, regulation, and disease mechanisms, it presents a powerful approach for expanding PTM coverage without compromising analytical rigor.</p><blockquote><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/tn_004377_ov_phosphorylation_ptm_etd_excedion_pro_tn004377_na_en_71f681655f.pdf"><span><strong>Download the technical note</strong></span> "<strong>Advancing phosphorylation, ADMA, and O-GlcNAc PTM analysis with HCD and EThcD on the Orbitrap Excedion Pro mass spectrometer</strong>"</a></h5></blockquote><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a>&nbsp;#PTM #OrbitrapExcedionPro #glycosylation #phosphorylation</p>

Phosphorylation, ADMA, and O-GlcNAc Analysis on the Orbitrap Excedion Pro Mass Spectrometer

<h4><strong>Latest edition of the Wiley Registry/NIST Mass Spectral Library for leading pharmaceutical, environmental, and forensic laboratories worldwide expands coverage to more than 1.2 million spectra</strong></h4><p>Wiley, a global leader in authoritative content and research intelligence, today released the new edition of the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2591"><strong>Wiley Registry/NIST Mass Spectral Library</strong></a>, a reference database that combines two essential mass spectrometry references in a single, integrated collection, giving scientists the full depth of both to identify unknown chemical compounds.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_Registry_NIST_EI_Mass_Spectral_Library_2026_4d3c8f440f.jpg" alt="Wiley: Wiley Registry/NIST EI Mass Spectral Library 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Wiley_Registry_NIST_EI_Mass_Spectral_Library_2026_4d3c8f440f.jpg 110w," sizes="100vw" width="1524" height="2161"></p><p>For years, laboratories doing GC-MS analysis have relied on Wiley’s renowned <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/887"><strong>Wiley Registry of Mass Spectral Data</strong></a> and the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2461"><strong>NIST/EPA/NIH EI Mass Spectral Library</strong></a> from the U.S. government’s National Institute of Standards and Technology (NIST) to power their analytical workflows. These two respected references are united in this database, one of the most comprehensive resources of its kind.</p><p>The<strong> new 2026 edition</strong> updates the collection, adding <strong>tens of thousands</strong> of <strong>newly validated compounds</strong> across both libraries and bringing the total to <strong>more than 1.2 million electron ionization (EI) mass spectra</strong>—unique chemical “signatures” used to identify substances.</p><p>The <strong>Wiley Registry/NIST Mass Spectral Library </strong>is part of Wiley’s growing portfolio of scientific data and research intelligence solutions, which spans spectral databases, chemistry and materials literature, and analytical tools supporting researchers from discovery through applied outcomes.</p><p>Wiley’s spectral database solutions are trusted by leading pharmaceutical, environmental, and forensic laboratories worldwide, reflecting Wiley’s mission to transform knowledge into actionable intelligence that helps researchers make confident, high-stakes decisions.</p><blockquote><p>“<i><strong>When a scientist runs a sample through a mass spectrometer, the results are only as good as the reference data behind them</strong></i>,” said Armughan Rafat, Wiley senior vice president and chief AI &amp; data analytics officer. “<i><strong>By uniting the Wiley Registry and the NIST Library in a single resource, we deliver the breadth, quality, and validation scientists need to identify unknown compounds faster and with confidence.</strong></i>”</p></blockquote><p>Available in the most common instrumentation manufacturer formats, the library supports high-confidence analysis across GC-MS workflows.</p><h4><strong>Spectral Databases</strong></h4><p>Spectral databases contain unique molecular “<strong>fingerprints</strong>” of substances captured through analytical techniques such as infrared (IR), mass spectrometry (MS), nuclear magnetic resonance (NMR), and Raman spectroscopy. By comparing experimental spectra against validated reference data, researchers can accurately identify unknown compounds across a wide range of applications. &nbsp;</p><h4><strong>About Wiley</strong></h4><p>Wiley is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what’s possible in science and learning.&nbsp;</p>

Wiley Releases Database Combining Two of the World’s Most Trusted Chemical Identification Resources

<p><strong>The countdown is almost over. In just one week, the international chromatography community will meet in Prague for the </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/events/644"><strong>35th International Symposium on Chromatography (ISC 2026)</strong></a><strong>, taking place from September 6–10, 2026. Whether your registration has been confirmed for months or you are still deciding whether to join, now is the time to finalize your plans. Here is what you need to know before ISC 2026 begins.</strong></p><p><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/companies/314"><strong>ISC</strong></a> is the oldest conference series dedicated to separation science, with symposia organized since 1956. This September, the Prague Congress Centre will welcome researchers, industry experts, instrument manufacturers, young scientists, and other specialists for five days of chromatography and separation science, covering everything from fundamental research to pharmaceutical, environmental, food, health, and omics applications.</p><p>But before the scientific sessions begin, there are a few practical details worth checking.</p><h4><strong>ISC officially starts on September 6 – but activities begin a day earlier</strong></h4><p>The official dates for ISC 2026 are <strong>Sunday, September 6 through Thursday, September 10</strong>, but for some participants the conference starts already on <strong>Saturday, September 5</strong>.</p><p>The first <strong>Short Courses </strong>are scheduled for Saturday (<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/6770"><strong>SC 1 – Modern HPLC Separation in Theory and Practice</strong></a> and <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7312"><strong>SC 2 – mzmine for LC-MS data analysis</strong></a>), with additional courses continuing on Sunday morning and afternoon. If you have registered for a Short Course, make sure to check its exact date and starting time before arranging your journey to Prague.</p><p>Sunday then marks the official opening of ISC 2026, with the <strong>Opening Ceremony, Award Ceremony, </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7361"><strong>plenary lectures</strong></a><strong>, and Welcome Reception</strong> introducing delegates to the week ahead.</p><h4><strong>Haven’t registered yet? You can still join ISC 2026</strong></h4><p>Missed the late-registration deadline? It is <strong>still possible to attend</strong>.</p><p>Onsite registration has been available since <strong>August 26, 2026</strong>, giving last-minute participants another opportunity to join the symposium. Current onsite registration fees are:</p><ul><li><strong>Industry:</strong> €1,150</li><li><strong>Academic:</strong> €890</li><li><strong>Student:</strong> €390</li><li><strong>Short Courses:</strong> €270</li></ul><p>The Short Course fee covers participation in up to three Short Courses.</p><p>One practical point for last-minute registration: bank-transfer payments closed on August 19, so <strong>only card payments are now accepted</strong>.</p><p>Full registration includes access to oral and poster sessions, the exhibition, the Sunday Welcome Reception, scheduled lunches and coffee breaks, the electronic Book of Abstracts, and a <strong>Prague public transportation pass</strong>.</p><h4><strong>Where is ISC 2026 and how do you get there?</strong></h4><p>ISC 2026 will take place at the:</p><p><strong>Prague Congress Centre</strong></p><ul><li>5. května 65</li><li>140 21 Prague 4</li><li>Czech Republic</li></ul><p>The venue is particularly easy to reach by public transport. It is located directly on Prague’s <strong>Metro Line C at Vyšehrad station</strong>, just around five minutes by metro from Muzeum station in the city centre.</p><p>The Prague Congress Centre brings the lecture halls, exhibition spaces, meeting rooms, and other conference facilities together in one venue, making it easy to move between scientific sessions, posters, industry activities, and the exhibition throughout the day.</p><p>And since full conference registration includes public transportation in Prague, getting around the city during ISC should be straightforward.</p><h4><strong>When can you pick up your conference materials?</strong></h4><p>The registration desk will already be open during the Short Courses and will remain available throughout the symposium.</p><p><strong>Registration opening hours:</strong></p><ul><li><strong>Saturday, September 5:</strong> 8:30–17:00</li><li><strong>Sunday, September 6:</strong> 7:30–19:00</li><li><strong>Monday, September 7:</strong> 7:30–18:00</li><li><strong>Tuesday, September 8:</strong> 7:30–19:00</li><li><strong>Wednesday, September 9:</strong> 8:00–18:00</li><li><strong>Thursday, September 10:</strong> 8:30–14:30</li></ul><p>If you are arriving in Prague on Sunday, allowing some extra time for registration before the Opening Ceremony will make the start of the conference considerably more relaxed.</p><h4><strong>Now is the time to build your personal ISC program</strong></h4><p>With several parallel sessions running throughout the week, trying to decide where to go only after arriving at the venue may mean missing something important.</p><p>The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7477"><strong>main scientific program</strong></a> is organized around three broad areas:</p><ul><li><strong>Fundamentals</strong></li><li><strong>Bioanalysis and omics applications</strong></li><li><strong>Hyphenated techniques</strong></li></ul><p>These are complemented by <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7280"><strong>Tutorials </strong></a><strong>+ Young Speakers</strong>, plenary and invited lectures, poster sessions, the international exhibition, vendor seminars, and industry-focused activities.</p><p>Before leaving for Prague, take another look at the <strong>Interactive Program</strong> and mark the lectures, posters, and other activities that are most relevant to you. If you are presenting your own work, this is also the right time to double-check your assigned session, room, and presentation time.</p><p>And don’t focus only on the oral program. <strong>Poster sessions and exhibition breaks</strong> are among the best opportunities to discuss new research directly with authors, meet instrument and technology specialists, and make new contacts.</p><h4><strong>Don’t overlook the vendor seminars and industry program</strong></h4><p>ISC 2026 is not limited to academic presentations. The conference also includes an extensive industry component, with activities covering current challenges in separation science and practical applications of new analytical technologies.</p><p>During the lunchtime sessions, participants can attend <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7736"><strong>vendor seminars</strong></a> presented by companies including <strong>Avantor, Shimadzu, Advanced Materials Technology, Restek, and Thermo Fisher Scientific</strong>. Topics range from stationary-phase selectivity and chromatographic modelling to HPLC and LC-MS column technologies and advanced characterization of biotherapeutics.</p><p>The conference also includes dedicated <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7777"><strong>Industry Activities</strong></a> <strong>from Monday through Wednesday</strong>, bringing together academic and industrial perspectives on topics relevant to analytical laboratories and the future of separation science. One of the discussions, for example, will examine how education in separation science can better reflect the skills required by modern industry, while another will focus on sustainability and the practical implementation of greener analytical workflows.</p><p>On Wednesday, participants can also join the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7801"><strong>Publishing Workshop</strong></a>, another activity worth adding to the schedule if scientific publishing is part of your work.</p><h4><strong>Test your chromatography knowledge at the ISC Quiz</strong></h4><p>Not every session needs to be completely serious.</p><p>On <strong>Tuesday, September 8 from 18:30 to 19:30</strong>, ISC will host an interactive <strong>Chromatography Quiz</strong>, combining practical questions, chromatography fundamentals, unusual facts, and lighter challenges.</p><p>There is <strong>no advance registration required</strong>. Any registered conference participant can join, but remember to bring a smartphone—the quiz uses live participation through a QR code.</p><p>Results will be scored in real time, and prizes will be awarded to the <strong>top three participants</strong>.</p><h4><strong>Start networking from the first evening</strong></h4><p>The scientific program may be the main reason to attend ISC, but the conversations between sessions can be equally valuable.</p><p>The first major networking opportunity comes immediately on Sunday.</p><p>The <strong>Welcome Reception</strong> will take place on <strong>September 6 from 18:30 to 20:00</strong> in the second-floor foyer of the Prague Congress Centre. It is open to registered participants and accompanying persons and includes a light buffet and drinks.</p><p>As it takes place immediately after the opening program, it is an ideal opportunity to reconnect with colleagues, meet new contacts, and start conversations before the full parallel scientific program begins on Monday.</p><p>Another social highlight will be the <strong>Gala Dinner on Wednesday, September 9 from 19:00 to midnight</strong> at the National House Vinohrady.</p><p>The Gala Dinner requires a separate <strong>€100 ticket</strong>, is not included in the standard registration fee, and has a smart-casual dress code. Participants should also note that transportation to and from the venue is not organized by the conference.</p><h4><strong>And perhaps leave a little time for Prague</strong></h4><p>A conference schedule can fill up quickly, but ISC 2026 is taking place in one of Europe’s most walkable cities.</p><p>If you find some free time between sessions, <strong>Vyšehrad is only about a 10-minute walk from the Prague Congress Centre</strong> and offers panoramic views across Prague and the Vltava River. It is an easy option for a short walk without travelling back into the historic city centre.</p><p><strong>See you at ISC 2026 in Prague!</strong></p>

ISC 2026 Starts in One Week: What You Need to Know

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Thermo Fisher Scientific

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

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Wiley

Phenomenex Strata X-CW Solid Phase Extraction (SPE)

Strata-X-CW weak cation-exchange SPE retains strong bases (pKa >8) with 100% organic wash for maximum cleanup. Available in tubes, 96-well plates, and giga formats.

<p><strong>Weak Cation Mixed-Mode Solid Phase Extraction (SPE)</strong></p><p>A weak cation-exchange functionalized polymeric sorbent that allows for complete retention of basic compounds with a <strong>pKa greater than 8</strong>, making <strong>100% organic wash conditions possible</strong>. A 100% organic wash ensures that the maximum amount of interferences are removed from the target compound.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_CW_SPE_b16a0e0baf.jpg" alt="Phenomenex: Strata-X-CW SPE" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_CW_SPE_b16a0e0baf.jpg 245w," sizes="100vw" width="500" height="268"></p><ul><li><strong>Recommended Use: </strong>Extraction of basic compounds, particularly strong bases</li></ul><h4><strong>Starting Method</strong></h4><h5><strong>For Bases with pKa &gt; 8</strong></h5><ul><li><strong>Column: </strong>1 mL Methanol</li><li><strong>Equilibrate: </strong>1 mL Water, pH 6-7</li><li><strong>Load: </strong>Diluted Sample, pH 6-7</li><li><strong>Wash 1: </strong>1 mL Water, pH 6-7</li><li><strong>Wash 2: </strong>1 mL Methanol (collect this fraction to analyze Neutrals/Acids)</li><li><strong>Elute Any Bases: </strong>2x 500 µL 5 % Formic Acid in Methanol</li><li><strong>Elute Weak Bases: </strong>2x 500 µL 5 % NH4OH in Methanol</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_single_tube_435d45d0ad.jpg" alt="Phenomenex: Strata X single tube" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_single_tube_435d45d0ad.jpg 156w," sizes="100vw" width="1080" height="1080"></p><p><i>Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.</i></p><h4><strong>Available Formats</strong></h4><ul><li><strong>96-Well-Plate</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_96_well_plate_9a66005814.jpg" alt="Phenomenex: Strata X 96-well plate" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_96_well_plate_9a66005814.jpg 156w," sizes="100vw" width="1080" height="1080"></p><ul><li><strong>1, 3, and 6mL Tubes</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_tubes_1_9b04cab6c1.jpg" alt="Phenomenex: Strata X 1, 3, and 6mL Tubes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_tubes_1_9b04cab6c1.jpg 156w," sizes="100vw" width="1080" height="1080"></p><ul><li><strong>Giga Tubes (12-150mL Tubes)</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_tubes_2_a8cd1706ec.jpg" alt="Phenomenex: Strata X Giga Tubes (12-150mL Tubes)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_tubes_2_a8cd1706ec.jpg 156w," sizes="100vw" width="1080" height="1080"></p>

Phenomenex Strata X Solid Phase Extraction (SPE)

Strata-X reversed phase SPE retains neutrals, acids, and bases via π-π, hydrogen bonding, and hydrophobic interactions. Robust cleanup under high organic wash.

<p><strong>Reversed Phase Solid Phase Extraction (SPE)</strong></p><p>A reversed phase functionalized polymeric sorbent that gives strong retention of neutral, acidic, or basic compounds under aggressive, high organic wash conditions. This sorbent relies on <strong>3 mechanisms of retention</strong>: <strong>pi-pi bonding</strong>, <strong>hydrogen bonding</strong> (dipole-dipole interactions), and <strong>hydrophobic interaction</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_d8f4451e42.jpg" alt="Phenomenex: Strata-X" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_d8f4451e42.jpg 245w," sizes="100vw" width="433" height="247"></p><ul><li><strong>Recommended Use: </strong>Extraction of neutrals and aromatics</li></ul><h4><strong>Starting Method</strong></h4><h5><strong>For Neutral Compounds</strong></h5><ul><li><strong>Column: </strong>1 mL Methanol</li><li><strong>Equilibrate: </strong>1 mL Water</li><li><strong>Load: </strong>Diluted Sample</li><li><strong>Wash: </strong>1 mL 5-60 % Methanol</li><li><strong>Elute:</strong> 2x 500 µL 2 % Formic Acid in Methanol/Acetonitrile</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_single_tube_435d45d0ad.jpg" alt="Phenomenex: Strata X single tube" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_single_tube_435d45d0ad.jpg 156w," sizes="100vw" width="1080" height="1080"></p><p><i>Based on 30 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.</i></p><h4><strong>Available Formats</strong></h4><ul><li><strong>96-Well-Plate</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_96_well_plate_9a66005814.jpg" alt="Phenomenex: Strata X 96-well plate" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_96_well_plate_9a66005814.jpg 156w," sizes="100vw" width="1080" height="1080"></p><ul><li><strong>1, 3, and 6mL Tubes</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_tubes_1_9b04cab6c1.jpg" alt="Phenomenex: Strata X 1, 3, and 6mL Tubes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_tubes_1_9b04cab6c1.jpg 156w," sizes="100vw" width="1080" height="1080"></p><ul><li><strong>Giga Tubes (12-150mL Tubes)</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Strata_X_tubes_2_a8cd1706ec.jpg" alt="Phenomenex: Strata X Giga Tubes (12-150mL Tubes)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Strata_X_tubes_2_a8cd1706ec.jpg 156w," sizes="100vw" width="1080" height="1080"></p>

Phenomenex Biozen N-Glycan Clean-Up

Biozen N-Glycan Clean-up enables fast, efficient SPE purification of labeled, released N-glycans using HILIC microelution, ideal for small sample volumes and LC-MS workflows.

<h4><strong>Easy Clean-up of Labeled, Released N-Glycans Using Solid Phase Extraction (SPE)</strong></h4><p>SPE HILIC stationary phase that excels at retention and recovery labeled released N-glycans. Microelution format allows for streamlined processing and clean-up of small sample volumes.</p><ul><li>Small volume format allows for more concentrated samples</li><li>Minimal elution solvent</li><li>Excellent retention and recovery of labeled, released N-glycans</li><li>Faster clean-up methods to save on sample prep time</li></ul><h4><strong>Protocol</strong></h4><ul><li><strong>96-Well Plate: </strong>Biozen N-Glycan Clean-up</li><li><strong>Part No.: </strong>8M-S009-NGA</li><li><strong>Condition: </strong>200 µL Water</li><li><strong>Equilibrate:</strong> 200 µL Water/Acetonitrile (15:85)</li><li><strong>Load:</strong> Labeled Sample (up to 400 µL of labeled sample)</li><li><strong>Wash: </strong>2x 600 µL Formic acid/Water/Acetonitrile (1:9:90)</li><li><strong>Elute: </strong>3x 30 µL 200 mM Ammonium acetate in Acetonitrile/Water (5:95) of labeled sample)</li><li><strong>Dilute:</strong> 100 µL Dimethylformamide and then 210 µL of Acetonitrile</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Biozen_N_Glycan_962a23eee6.jpg" alt="Phenomenex: Biozen N-Glycan Clean-up" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Biozen_N_Glycan_962a23eee6.jpg 245w," sizes="100vw" width="1444" height="424"></p>

Phenomenex Clarity OTX Clean-Up

Rapid 15-minute clean-up of biological samples using Clarity OTX SPE enables efficient isolation of RNA- and DNA-based therapeutics without LLE, optimized for LC-MS bioanalysis.

<h4><strong>15 Minute Clean Up from Biological Samples</strong></h4><p><strong>Isolate RNA and DNA-based therapeutics / metabolites from biological fluids and tissues in less time with Clarity OTX solid phase extraction (SPE) and buffer products.</strong></p><ul><li>No liquid-liquid extraction (LLE) required required</li><li>&gt;80 % typical extraction recoveries</li><li>Optimized for LC-MS bioanalysis</li></ul><h3><app-cb-header style="color:rgb(65, 66, 69);font-family:proxima-nova, sans-serif;font-size:16px;font-style:normal;font-weight:400;letter-spacing:normal;text-align:left;text-indent:0px;text-transform:none;"><div><div><h2 style="border-bottom:1px solid rgb(51, 51, 51);color:rgb(0, 41, 72);font-size:32px;font-style:normal;font-weight:400;line-height:1.2;"><div>General Extraction</div></h2></div></div></app-cb-header><app-cb-fourtext-eightimage style="color:rgb(65, 66, 69);font-family:proxima-nova, sans-serif;font-size:16px;font-style:normal;font-weight:400;letter-spacing:normal;text-align:left;text-indent:0px;text-transform:none;"><div><div><div style="flex-wrap:wrap;"><div style="flex:0 0 100%;"><h2 style="color:rgb(0, 41, 72);font-size:32px;font-weight:400;line-height:1.2;">Common Extraction Procedure (~180 minutes)</h2></div></div></div></div></app-cb-fourtext-eightimage><strong>General Extraction</strong></h3><h4><strong>Common Extraction Procedure (~180 minutes)</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Clarity_OTX_Clean_Up_e317411382.jpg" alt="Phenomenex: Clarity OTX Clean-Up: Common Extraction Procedure (~180 minutes)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Clarity_OTX_Clean_Up_e317411382.jpg 245w," sizes="100vw" width="678" height="374"></p><h5><strong>Suitable for Most Oligo Therapeutics &amp; Samples</strong></h5><p><strong>Oligo types / Sample Types</strong></p><ul><li>DNA: Plasma</li><li>Aptamers: Serum</li><li>RNAi/siRNA: Urine</li><li>Thioates: Tears</li><li>Lipid-conjugates: Saliva</li><li>Liposome encapsulated: Tissue</li></ul><h4><strong>Extraction Protocol</strong></h4><p><strong>Sample Pre-Treatment</strong></p><ul><li><strong>Tissue:</strong><ul><li>Proteinase K digestion or homogenize</li><li>Mix 1-to-1 with Lysis-Loading buffer</li></ul></li><li><strong>Biological Fluids: </strong>Mix 1-to-1 with Lysis-Loading buffer</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Clarity_OTX_Clean_Up_2_fd322c63cd.jpg" alt="Phenomenex: Clarity OTX Clean-Up: Extraction Protocol" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Clarity_OTX_Clean_Up_2_fd322c63cd.jpg 245w," sizes="100vw" width="1031" height="494"></p>

Phenomenex Zebron Z-Guard GC Columns

Phenomenex Zebron Z-Guard GC columns protect analytical columns, improve peak shape and sensitivity, and extend column lifetime. Individually QC tested.

<h4><strong>Protect and Extend Column Lifetime</strong></h4><ul><li>Individually QC tested to ensure the highest level of quality</li><li>Extend column lifetime by preventing stationary phase damage</li><li>Improve separation and peak shapes (especially early elutors)</li><li>Improve sensitivity and accuracy of quantitative results</li><li>Available as individual guard columns or as complete kits with connectors</li></ul><p>To ensure that all Z-Guards are the highest possible quality, we individually test each one! The columns are attached to a reference <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1577"><strong>Zebron ZB-5 column</strong></a> and are tested using our specially designed QC mix. We carefully monitor activity, bleed, and stability. This way, we are able to say with confidence that Z-Guards will provide the low activity and high quality your methods require.</p><h5><strong>Recommended Use</strong></h5><p>Extends column lifetime by preventing stationary phase damage and improves separation, peak shapes (especially early elutors), sensitivity, and accuracy of quantitative results</p><h4><strong>Zebron Z-Guard Phase Information</strong></h4><p>Z-Guard columns are universal GC guard columns, designed for use with virtually any GC capillary column, from virtually any manufacturer.</p><ul><li>Extend column lifetime by preventing stationary phase damage</li><li>Improve separation, peak shapes (especially early elutors), sensitivity, and accuracy of quantitative results</li><li>Alternative to Agilent, Restek, Supelco, and many more</li></ul><h5><strong>Easy Use Z-Guard Column Kits</strong></h5><p>Try Z-Guard columns individually or get the convenient, complete kit. Each kit includes:</p><ul><li>5 or 10 meters of deactivated fused-silica tubing</li><li>5 universal connectors</li><li>0.5 mL of high-temperature polyimide resin</li></ul><h5><strong>Guard Column Usage</strong></h5><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_Z_Guard_GC_Columns_Guard_column_usage_675cd327b8.jpg" alt="Phenomenex: Zebron Z-Guard GC Columns: Guard column usage" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_Z_Guard_GC_Columns_Guard_column_usage_675cd327b8.jpg 245w," sizes="100vw" width="1039" height="359"></p><h5><strong>Tips: Using Z-Guard Columns</strong></h5><p>When using a guard at high temperatures, make sure that the press-fit connection is secure.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_Z_Guard_GC_Columns_Using_Z_guard_columns_6842e6a4bd.jpg" alt="Phenomenex: Zebron Z-Guard GC Columns: Using Z-guard columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_Z_Guard_GC_Columns_Using_Z_guard_columns_6842e6a4bd.jpg 245w," sizes="100vw" width="414" height="164"></p><p>The most important aspect of a good seal is a good column cut.</p><ul><li>The column end should be square and smooth (like a straw). Any irregularities will cause leaks.</li><li>Columns are long - repeat cutting until a good cut is achieved.</li><li>Lightly scoring the column usually creates a cleaner opening.</li></ul>

Phenomenex Phenex LC/GC Approved Syringe Filters

Phenex syringe filters deliver fast, reliable sample filtration with excellent flow rates and broad chemical compatibility. Designed to protect columns, reduce downtime, and ensure particulate-free samples for LC, GC, and MS analysis.

<p><strong>Phenex syringe filters are designed for efficient and rapid filtration of almost any solution prior to analysis, and are optimized for superior flow rates and high-throughput. Proper syringe filter membrane and size selection is the key to choosing the best product to maintain the integrity of your sample components as well as to protect your system from particulate contamination. Phenex offers a wide variety of membranes ideal for any application.</strong></p><h5><strong>Try our Phenex Syringe Filters for:</strong></h5><ul><li>High quality filtration product</li><li>Increased column lifetime</li><li>Less system downtime</li><li>Low protein absorption</li></ul><h4><strong>Phenex Offers:</strong></h4><ul><li>Broad chemical compatibility</li><li>Minimized extractables</li><li>Excellent flow rate</li><li>High total throughput</li><li>Certified quality</li><li>100 % integrity tested</li><li>Low hold-up volume</li><li>Low protein adsorption</li><li>Bi-directional use</li></ul><h3><strong>Maximum Quality</strong></h3><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_2_44145fa074.jpg" alt="Phenomenex: Phenex LC-GC Approved Syringe Filters: Maximum Quality" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_2_44145fa074.jpg 218w," sizes="100vw" width="1156" height="828"></p><h5><strong>A: Identification</strong></h5><ul><li>Syringe filter membrane type and pore size are clearly marked on each syringe filter</li></ul><h5><strong>B: Luer Lock Inlet Tip</strong></h5><ul><li>Secures connections to prevent “blow off”</li></ul><h5><strong>C: Sample Distribution Rings</strong></h5><ul><li>Creates even sample distribution for high sample flow rates</li></ul><h5><strong>D: Medical Grade Polymer Housing</strong></h5><p>Offers the most inert syringe filter and helps eliminate unwanted secondary interactions with the filter housing</p><h5><strong>E: Ultrasonically Welded</strong></h5><ul><li>Ensures robust housing - filter integrity</li></ul><h4><strong>Guaranteed Reliability and Consistency</strong></h4><p>Quality filtration products from Phenomenex offer a convenient way to clean up your samples - for improved analytical results with a simple method. Phenex syringe filters are designed for efficient and rapid filtration of almost any solution prior to analysis, and are optimized for superior flow rates and high-throughput. Phenex offers a wide variety of membranes ideal for any application.</p><ul><li>High quality filtration product</li><li>Increased column lifetime</li><li>Less system downtime</li></ul><p>The housing attaches to any standard luer lock syringe, so the sample can easily be pushed through the membrane with minimal pressure. The result is a particulate-free eluent that is ready for use with LC, GC, or other analytical techniques. One of the most popular sample preparation methods is filtration using a sample preparation solution. It has the ability to remove particulates before injection onto the column and the ability to use it in parallel with another sample preparation technique. It requires no method development.</p><ul><li><strong>A:</strong> Particulates Trapped</li><li><strong>B:</strong> Particulate-free Sample</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_631acccb54.jpg" alt="Phenomenex: Phenex LC/GC Approved Syringe Filters: Guaranteed Reliability and Consistency" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_631acccb54.jpg 42w," sizes="100vw" width="143" height="523"></p><h3><strong>Recommendation Based on Your Industry</strong></h3><h5><strong>Environmental</strong></h5><p>Water, wastewater, soil and sludge, and pollution control samples are especially challenging. No matter the sample type, Phenex offers filtration products to meet your demanding requirements.</p><ul><li><strong>Recommended Filter: </strong>GF/NY</li><li><strong>First Alternative:</strong> RC</li></ul><h5><strong>Pharmaceutical / Biotech</strong></h5><p>At every stage of the drug discovery process target compounds must be isolated, purified, and prepared prior to testing. Sample complexity in DMPK work can be even more challenging. Difficult samples such as serum, urine, and other physiological fluids are easily filtered and clarified using Phenex syringe filters.</p><ul><li><strong>Recommended Filter: </strong>PES</li><li><strong>First Alternative: </strong>RC</li></ul><h5><strong>Clinical / Toxicology</strong></h5><p>Removal of particulate matter to sub-micron levels is critical before any clinical sample is injected into an LC, GC or mass spectrometer. At every stage in toxicology, samples should be filtered, preferably with a rapid and simple sample preparation method to reduce downtime in the fast paced environment. Phenex is designed for higher flow rates and throughputs than those of competing products.</p><ul><li><strong>Recommended Filter: </strong>RC</li><li><strong>First Alternative: </strong>PES</li></ul><h5><strong>Food and Beverage</strong></h5><p>Food safety is more important than ever and lower detection limits are making analysis even more challenging. Accurate and reliable testing is critical and Phenex filters are routinely used in preparation for analysis of pesticides, herbicides, fungicides, flavors, and fragrances. For samples with large amounts of particulate and/or large fibrous matter, use a glass fiber prefilter.</p><ul><li><strong>Recommended Filter: </strong>GF/NY</li><li><strong>First Alternative: </strong>RC</li></ul><h3><strong>How to Use Phenex Syringe Filters</strong></h3><h4><strong>Easy to assemble and even easier to get consistent and particulate-free samples</strong></h4><h5><strong>Step 1: Load</strong></h5><ul><li>Fill a syringe barrel with the liquid sample. Allow a small amount of air (approximately 10 % of the sample volume) to enter the syringe. The air is used as a purge to minimize fluid retention when expelling the sample from the syringe (Step 3 below).</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_Step_1_f8246ba832.jpg" alt="Phenomenex: Phenex LC/GC Approved Syringe Filters - Step 1: Load" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_Step_1_f8246ba832.jpg 155w," sizes="100vw" width="423" height="427"></p><h5><strong>Step 2: Assemble</strong></h5><ul><li>Twist the luer lock end of the filter securely onto the syringe.</li><li><strong>Caution: </strong>Do not use syringes without a matching luer lock, otherwise the pressure applied may cause the filter to come off unexpectedly.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_Step_2_2833584d34.jpg" alt="Phenomenex: Phenex LC/GC Approved Syringe Filters: Step 2: Assemble" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_Step_2_2833584d34.jpg 158w," sizes="100vw" width="349" height="344"></p><h5><strong>Step 3: Filter</strong></h5><ul><li>Apply gentle pressure to the syringe plunger.</li><li><strong>Caution: </strong>Small syringes can generate excessive pressures.) Push the liquid sample, as well as the remaining air, through the syringe filter to maximize sample recovery.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_Step_3_d8c5f61231.jpg" alt="Phenomenex: Phenex LC/GC Approved Syringe Filters - Step 3: Filter" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Phenex_LC_GC_Approved_Syringe_Filters_Step_3_d8c5f61231.jpg 177w," sizes="100vw" width="375" height="331"></p>

KNAUER Sepapure Laboratory Filtration

Sepapure laboratory filtration includes syringe filters, membranes, and filter units for clean, precise, and reproducible results.

<p><strong>The Sepapure® Laboratory Filtration range provides a comprehensive solution for laboratory sample filtration, focusing on purity, precision, and reproducibility.</strong></p><p>The portfolio includes:</p><ul><li><strong>syringe filters</strong></li><li><strong>membrane disc filters</strong></li><li><strong>filter units</strong></li><li><strong>filter holders</strong></li></ul><p>These products are designed to ensure <strong>maximum sample recovery, minimal loss, and broad compatibility</strong> across analytical, pharmaceutical, and routine laboratory applications.</p><h4><span><strong>Key Features</strong></span></h4><ul><li>High filtration purity and reproducibility</li><li>Minimal sample loss</li><li>Color-coded identification</li><li>Wide range of membrane materials</li><li>Broad application compatibility</li><li>Pressure resistance (&gt;6 bar)</li><li>Eco-friendly reusable solutions</li></ul><h3><span><strong>Product Variants</strong></span></h3><h4><span><strong>Sepapure® Syringe Filters</strong></span></h4><ul><li>Color-coded and labeled</li><li>Integrated polypropylene prefilter</li><li>Low hold-up volume → minimal sample loss</li><li>High pressure resistance (&gt;6 bar)</li><li>Wide application compatibility</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Sepapure_Laboratory_Filtration_5_00f6e96bbe.jpg" alt="KNAUER: Sepapure® Syringe Filters" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Sepapure_Laboratory_Filtration_5_00f6e96bbe.jpg 245w," sizes="100vw" width="1216" height="196"></p><h4><span><strong>Sepapure® Membrane Disc Filters</strong></span></h4><ul><li>Various membrane materials</li><li>Efficient separation for complex samples</li><li>High filtrate purity</li><li>Suitable for lab and research use</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Sepapure_Laboratory_Filtration_3_1e207905e0.jpg" alt="KNAUER: Sepapure® Membrane Disc Filters" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Sepapure_Laboratory_Filtration_3_1e207905e0.jpg 156w," sizes="100vw" width="1000" height="1000"></p><h4><span><strong>Filter Units (Glass Vacuum Units)</strong></span></h4><ul><li>Glass vacuum filtration systems</li><li>Available volumes: 1000 mL and 2000 mL</li><li>Ground glass or rubber joints</li><li>Compatible with membrane filters</li><li>High chemical resistance and durability</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Sepapure_Laboratory_Filtration_2_86cf0cc5f8.jpg" alt="KNAUER: Filter Units (Glass Vacuum Units)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Sepapure_Laboratory_Filtration_2_86cf0cc5f8.jpg 156w," sizes="100vw" width="1000" height="1000"></p><h4><span><strong>Filter Holders</strong></span></h4><ul><li>Reusable and durable</li><li>Eco-friendly (waste reduction)</li><li>Versatile applications</li><li>High mechanical stability</li></ul><h4><span><strong>Typical Applications</strong></span></h4><ul><li>Sample preparation for HPLC/LC-MS</li><li>Mobile phase filtration</li><li>Environmental analysis</li><li>Pharmaceutical QC</li><li>Biochemical and clinical workflows</li></ul>

KNAUER Vials & Caps

KNAUER vials and caps for HPLC/UHPLC with high chemical resistance, multiple closure types, and optimized solutions for precise sample handling.

<p><strong>The KNAUER Vials &amp; Caps range provides a complete solution for sample preparation in HPLC/UHPLC analysis, where precision, purity, and sample integrity are critical.</strong></p><p>Selecting the correct vial and cap combination directly impacts:</p><ul><li><strong>result reproducibility</strong></li><li><strong>contamination prevention</strong></li><li><strong>minimization of evaporation</strong></li><li><strong>autosampler performance</strong></li></ul><p>KNAUER offers a wide variety of configurations including:</p><ul><li>glass types (clear / amber)</li><li>closure types (screw, crimp, snap)</li><li>septa (pre-slit / non pre-slit)</li><li>accessories (µ-inserts for small volumes)</li></ul><h3><span><strong>Product Variants</strong></span></h3><h4><span><strong>Sample Vials</strong></span></h4><ul><li><strong>Neck types:</strong><ul><li>screw neck</li><li>crimp neck</li><li>snap ring</li></ul></li><li><strong>Materials:</strong><ul><li>clear glass</li><li>amber glass (UV protection)</li></ul></li><li>High chemical resistance</li><li>Compatible with micro-inserts</li></ul><h4><span><strong>Caps</strong></span></h4><ul><li>Compatible with all vial types</li><li><strong>Options:</strong><ul><li>pre-slit septa</li><li>solid septa</li></ul></li><li>Optimized sealing</li><li>Suitable for automated and manual sampling</li></ul><h3><span><strong>Vial Selection Guide</strong></span></h3><h4><span><strong>Glass Color</strong></span></h4><ul><li><strong>Amber glass</strong><ul><li>UV protection</li><li>ideal for <strong>light-sensitive compounds (vitamins, steroids, pharmaceuticals)</strong></li></ul></li><li><strong>Clear glass</strong><ul><li>maximum visibility</li><li>ideal for <strong>routine applications</strong></li></ul></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Vials_and_Caps_glass_color_bd1238185e.jpg" alt="KNAUER: Vials &amp; Caps - Glass color" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Vials_and_Caps_glass_color_bd1238185e.jpg 155w," sizes="100vw" width="435" height="437"></p><h4><span><strong>Closure Types</strong></span></h4><ul><li><strong>Screw Neck</strong><ul><li>resealable</li><li>ideal for <strong>volatile samples and storage</strong></li></ul></li><li><strong>Crimp Neck</strong><ul><li>tightest seal</li><li>ideal for <strong>highly volatile samples</strong></li></ul></li><li><strong>Snap Ring</strong><ul><li>tool-free handling</li><li>suitable for <strong>short-term use</strong></li></ul></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Vials_and_Caps_closure_type_c6c7a61418.jpg" alt="KNAUER: Vials &amp; Caps - Closure type" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Vials_and_Caps_closure_type_c6c7a61418.jpg 245w," sizes="100vw" width="978" height="389"></p><h4><span><strong>Septum Types</strong></span></h4><ul><li><strong>Pre-slit septum</strong><ul><li>easier needle penetration</li><li>ideal for <strong>autosamplers</strong></li><li>prevents vacuum formation</li></ul></li><li><strong>Non pre-slit septum</strong><ul><li>tighter seal</li><li>ideal for <strong>storage and evaporation control</strong></li></ul></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Vials_and_Caps_septum_type_0b6afde0e9.jpg" alt="KNAUER: Vials &amp; Caps - Septum type" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Vials_and_Caps_septum_type_0b6afde0e9.jpg 245w," sizes="100vw" width="551" height="343"></p><h4><span><strong>µ-Inserts (Small Volumes)</strong></span></h4><ul><li>Reduce sample volume requirements</li><li>Maximize recovery</li><li>Ideal for valuable or limited samples</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Vials_and_Caps_3_b697f0f41b.webp" alt="KNAUER: Vials &amp; Caps - Micro inserts" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Vials_and_Caps_3_b697f0f41b.webp 239w," sizes="100vw" width="1000" height="653"></p>

KNAUER Capillaries & Tubing

KNAUER Capillaries & Tubing provide high-pressure LC capillaries and tubing up to 1200 bar, including MarvelXACT™ tool-free UHPLC connection systems.

<p><strong>KNAUER Capillaries &amp; Tubing provide a wide range of capillaries and tubing solutions for analytical and preparative HPLC, UHPLC, and FPLC applications. The portfolio includes stainless steel, PEEK, PTFE, and other tubing materials designed for reliable LC connections at pressures up to 1200 bar. The range also features innovative MarvelXACT™ capillaries with tool-free fingertight connections and a patented torque-limiting mechanism for secure and trouble-free operation.</strong></p><h4><span><strong>Key Features</strong></span></h4><ul><li>Capillaries and tubing for HPLC, UHPLC, and FPLC</li><li>Maximum pressure up to 1200 bar</li><li>Materials include stainless steel, PEEK, PTFE, PFA, ETFE, and more</li><li>Suitable for analytical and preparative applications</li><li>MarvelXACT™ fingertight connection system</li><li>Patented torque-limiting “click” mechanism</li><li>Automatic adjustment to different port depths</li><li>More than 100 connection/disconnection cycles</li><li>PEEK capillaries for maximum biocompatibility</li><li>User-cuttable standard capillaries</li><li>Tubing for low-pressure solvent and waste lines</li></ul><h4><span><strong>MarvelXACT™ Capillaries</strong></span></h4><ul><li>Recommended for AZURA® Analytical systems</li><li>Tool-free installation</li><li>Flexible 1/32” OD tubing</li><li>compatible with KNAUER standard 1/16” receiving ports</li><li>Pre-installed fittings</li><li>Eliminates under- and over-tightening</li><li>Patented torque-limiting mechanism</li><li>Flexible tubing for easy routing</li><li>Bottom-port sealing without ferrules</li></ul><h4><span><strong>Available Options</strong></span></h4><ul><li>Stainless steel capillaries for high-pressure applications</li><li>PEEK capillaries for biocompatible workflows</li><li>PTFE, PFA, ETFE, and Tefzel® tubing</li><li>User-customizable capillary lengths</li><li>Tubing for solvent and waste connections</li></ul>

KNAUER Pipettes

KNAUER Pipetting Solutions combine ergonomic BlueOrchid pipettes, high-purity pipette tips, reload systems, and sustainable rack boxes for accurate, comfortable, and contamination-free liquid handling workflows.

<p><strong>KNAUER Pipetting Solutions combine ergonomic design, precision engineering, and high-quality consumables to support reliable liquid handling workflows in analytical, biological, and routine laboratory applications. The portfolio includes BlueOrchid micropipettes, premium pipette tips, reload systems, and sustainable rack boxes designed to deliver maximum accuracy, user comfort, and workflow efficiency.</strong></p><h4><span><strong>BlueOrchid Pipettes</strong></span></h4><p>KNAUER BlueOrchid pipettes are designed for effortless daily pipetting with reduced hand strain and reliable long-term performance. The lightweight and balanced construction, combined with a silicone-based shock absorption mechanism and magnet-assisted piston system, minimizes pipetting and tip ejection forces for fatigue-free operation.</p><p>The pipettes feature intuitive one-handed volume adjustment with a secure locking mechanism and a large 4-digit display for easy readability. All models are ISO 8655-6 calibrated to ensure high accuracy and precision.</p><p><strong>Available single-channel volume ranges include:</strong></p><ul><li>0.1–2.5 µL</li><li>0.5–10 µL</li><li>2–20 µL</li><li>5–50 µL</li><li>10–100 µL</li><li>20–200 µL</li><li>100–1,000 µL</li><li>500–5,000 µL</li><li>1,000–10,000 µL</li><li>Fixed-volume 150 µL model</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Pipettes_6_3d401a1c67.jpg" alt="KNAUER: Pipettes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Pipettes_6_3d401a1c67.jpg 241w," sizes="100vw" width="1046" height="677"></p><p><strong>Key characteristics:</strong></p><ul><li>Ergonomic low-force pipetting design</li><li>Color-coded volume identification</li><li>Autoclavable and chemically resistant construction</li><li>UV-resistant materials</li><li>No recalibration required after sterilization</li><li>Compatible with KNAUER pipette tips and many third-party brands</li></ul><h4><span><strong>Pipette Tips</strong></span></h4><p>KNAUER pipette tips are manufactured in Germany from high-quality medical-grade virgin polypropylene to ensure contamination-free and highly reproducible pipetting. The product range includes eight <strong>tip sizes from 10 µL to 10 mL</strong>, including <strong>extra-long 10 µL tips</strong> optimized for recovery of very small sample volumes.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Pipette_Tips_71e87b2e4b.webp" alt="KNAUER: Pipette Tips" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Pipette_Tips_71e87b2e4b.webp 100w," sizes="100vw" width="690" height="1077"></p><p>The tips are designed with optimized cone geometry for secure pipette fitting and low-force attachment and ejection. A conical tip opening and ultra-smooth internal surface reduce droplet formation and minimize sample retention.</p><p><strong>Key advantages:</strong></p><ul><li>Free of DNase, RNase, human DNA, pyrogens, and PCR inhibitors</li><li>Autoclavable and non-wettable</li><li>US FDA-approved virgin polypropylene</li><li>Universal compatibility with major pipette brands</li><li>Graduation marks for rapid volume verification</li><li>Available in bulk bags or reload systems</li><li>Yellow and blue versions available for selected tip sizes</li></ul><p><strong>Available packaging options:</strong></p><ul><li>Bulk bags for economical refilling</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Bulk_Bags_f99e73dba3.webp" alt="KNAUER: Bulk Bags" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Bulk_Bags_f99e73dba3.webp 156w," sizes="100vw" width="690" height="690"></p><ul><li>Reload units for fast one-handed box refilling and reduced plastic waste</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Reloads_48b0e2cf9d.webp" alt="KNAUER: Reload units" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Reloads_48b0e2cf9d.webp 245w," sizes="100vw" width="690" height="343"></p><h4><span><strong>Reload Systems</strong></span></h4><p>KNAUER reload systems are designed to simplify laboratory workflows while reducing environmental impact. <strong>Reloads</strong> are available for <strong>10 µL, 200 µL, and 1,000 µL pipette tips</strong> and allow quick replacement of empty rack inserts with minimal handling effort.</p><p><strong>Advantages of reload systems:</strong></p><ul><li>One-handed reload operation</li><li>Reduced plastic consumption</li><li>Space-saving storage</li><li>Color-coded rack inserts for quick identification</li><li>Optimized for routine high-throughput workflows</li></ul><h4><span><strong>Rack Boxes</strong></span></h4><p>KNAUER rack boxes provide secure and sustainable storage for pipette tips. The boxes are manufactured from 100% recycled plastic sourced from pipette tip production and are fully autoclavable.</p><p>The stackable design allows safe and space-efficient storage, while the easy-open lid and color-coded rack inserts improve laboratory organization and workflow efficiency.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/KNAUER_Tip_boxes_1d59517540.webp" alt="KNAUER: Rack boxes" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_KNAUER_Tip_boxes_1d59517540.webp 245w," sizes="100vw" width="1024" height="427"></p><p><strong>Available rack box versions:</strong></p><ul><li>10 µL / 10 µL XL pipette tips</li><li>200 µL / 300 µL pipette tips</li><li>1,000 µL pipette tips</li><li>1,250 µL pipette tips</li></ul><p><strong>Key features:</strong></p><ul><li>Made from 100% recycled plastic</li><li>Stackable construction</li><li>Secure tip positioning</li><li>Easy one-handed handling</li><li>Compatible with single- and multi-channel pipettes</li><li>Sustainable and reusable design</li></ul>

Products from category Consumables - page 1

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