Manufacturer
Phenomenex
Phenomenex
Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories. From drug discovery and pharmaceutical development to disease diagnosis, food safety to environmental analysis, Phenomenex chromatography solutions accelerate science and help researchers improve global health and well-being.
Distributor
Phenomenex
Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.
(310) 212-0555 USA
www.phenomenex.com
[email protected]
AllConsumablesSPE sample preparation
Phenomenex Clarity OTX Clean-UpRapid 15-minute clean-up of biological samples using Clarity OTX SPE enables efficient isolation of RNA- and DNA-based therapeutics without LLE, optimized for LC-MS bioanalysis.
Features

Phenomenex Clarity OTX Clean-Up

15 Minute Clean Up from Biological Samples

Isolate RNA and DNA-based therapeutics / metabolites from biological fluids and tissues in less time with Clarity OTX solid phase extraction (SPE) and buffer products.

  • No liquid-liquid extraction (LLE) required required
  • >80 % typical extraction recoveries
  • Optimized for LC-MS bioanalysis

General Extraction

Common Extraction Procedure (~180 minutes)

General Extraction

Common Extraction Procedure (~180 minutes)

Phenomenex: Clarity OTX Clean-Up: Common Extraction Procedure (~180 minutes)Phenomenex: Clarity OTX Clean-Up: Common Extraction Procedure (~180 minutes)

Suitable for Most Oligo Therapeutics & Samples

Oligo types / Sample Types

  • DNA: Plasma
  • Aptamers: Serum
  • RNAi/siRNA: Urine
  • Thioates: Tears
  • Lipid-conjugates: Saliva
  • Liposome encapsulated: Tissue

Extraction Protocol

Sample Pre-Treatment

  • Tissue:
    • Proteinase K digestion or homogenize
    • Mix 1-to-1 with Lysis-Loading buffer
  • Biological Fluids: Mix 1-to-1 with Lysis-Loading buffer

Phenomenex: Clarity OTX Clean-Up: Extraction ProtocolPhenomenex: Clarity OTX Clean-Up: Extraction Protocol

Manufacturer
Phenomenex
Phenomenex
Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories. From drug discovery and pharmaceutical development to disease diagnosis, food safety to environmental analysis, Phenomenex chromatography solutions accelerate science and help researchers improve global health and well-being.
Distributor
Phenomenex
Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.
(310) 212-0555 USA
www.phenomenex.com
[email protected]
 

News

SPE Troubleshooting: Why Won't My Sample Flow Through the SPE Cartridge?
Article | Academy

SPE Troubleshooting: Why Won't My Sample Flow Through the SPE Cartridge?

Learn the most common causes of SPE cartridge flow problems and how to troubleshoot them. Identify issues related to samples, solvents, manifold pressure, and precipitation.
Phenomenex
SPE Troubleshooting: Understanding and Resolving Low Recovery in Solid Phase Extraction
Article | Academy

SPE Troubleshooting: Understanding and Resolving Low Recovery in Solid Phase Extraction

Low SPE recovery does not have to mean method failure. Learn how fraction collection and analysis can identify analyte losses and guide effective troubleshooting steps.
Phenomenex