<p><strong>Is your lab ready for the new academic year? As students and teachers return to the laboratory, now is a great time to prepare your chromatography systems for the semester ahead.</strong></p><p>Now with <strong>20% total discount</strong> on a <strong>new </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/999"><strong>Clarity Chromatography Software</strong></a> for customers from educational institutions. In addition, customers purchasing a new license for Clarity Chromatography Software will receive a <strong>free copy of </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1000"><strong>Clarity Offline Chromatography Software</strong></a>.</p><blockquote><p class="cke-user_style-important"><strong>👉Promotion code: MKT2114</strong></p><p>The offer is valid through the <strong>end of October 2026.</strong></p></blockquote><p><strong>The latest version of Clarity Chromatography Software - 10.2 was released in June 2026! </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7512"><strong>Read the article HERE.</strong></a></p>

Back to School: 20% Off Clarity Chromatography Software

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 7th September 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you application notes by <strong>Agilent Technologies </strong>and <strong>Shimadzu, </strong>presentation by<strong> MDCW / Los Alamos National Laboratory </strong>and other document by<strong> Thermo Fisher Scientific!</strong></p><h3><strong>1. Agilent Technologies: Quantification of Microplastics in Soil and Sediment Using Dry-Ice-Assisted Fractionation</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_8700_ldir_chemical_imaging_system_5994_9256en_agilent_94102868f0.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>Microplastics are now widely reported in terrestrial environments, including soil and sediments, raising concerns about soil health and potential human exposure pathways (for example, in agricultural regions).1,2 Microplastics can be classified by polymer type and particle characteristics (size, color, and morphology such as fragments and fibers) and may be primary (manufactured small) or secondary (formed from the breakdown of larger plastic items). In this workflow, microplastics were defined as particles ranging from 1 µm to &lt;&nbsp;1,000 µm.&nbsp;</p><p>Reliable and reproducible quantification remains challenging, limiting comparability between studies and complicating risk assessment and the development of defensible monitoring approaches. Challenges occur across the workflow, from sampling and extraction through to instrumental analysis and reporting, and are exacerbated by environmental heterogeneity, inconsistent reporting, and the limited availability of standard reference materials and routine quality control&nbsp;procedures.&nbsp;</p><p>Conventional soil microplastics workflows typically include drying, density separation and/or flotation, chemical digestion to remove organic matter, and filtration prior to spectroscopic identification.3–5 In this application note, we combined a fast, practical extraction workflow with consistent, automated instrumental analysis by adapting foam fractionation to soil and sediment. Several bubbling strategies (soda water, compressed air, and nitrogen) were evaluated; dry ice was selected because it produced vigorous mixing and stable foam in the presence of a surfactant, enhancing exposure of particles to the foam layer and improving isolation from the matrix.&nbsp;</p><p>All method validation and environmental sample analyses were performed using an Agilent 8700 LDIR chemical imaging system, providing automated particle location, polymer identification, sizing, and counting. A particle-based internal standard was integrated into the workflow as a simple, sample‑specific check on extraction and transfer&nbsp;performance.</p><h4><strong>Results and discussion</strong></h4><h5><strong>Environmental sample overview&nbsp;</strong></h5><p>The workflow was applied to environmental samples from Victoria, Australia, including three soil types (chromosol, dermosol, and hydrosol) and freshwater sediment from three locations. In all samples, the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=10&amp;search=8700%C2%A0LDIR"><strong>8700&nbsp;LDIR</strong></a> provided automated particle identification, sizing, and counting of microplastics following dry-ice-assisted fractionation and density separation. Soil concentrations ranged from 4,360 to 102,000 microplastics kg–1, with acrylonitrile butadiene styrene and polyamide the most frequently detected polymers. Sediment concentrations ranged from 41,400 to 127,000 microplastics kg–1 and were dominated by fragments in the 10 to 50 µm size&nbsp;range.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>This study demonstrates the suitability of the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=10&amp;search=8700%C2%A0LDIR"><strong>Agilent 8700 LDIR chemical imaging system</strong></a> for automated, particle‑based quantification of microplastics in complex soil and sediment matrices. When combined with dry-ice-assisted foam fractionation, the 8700 LDIR provided reliable identification, sizing, and counting of microplastics across a broad size and density range with high&nbsp;repeatability.&nbsp;</p><p>The integration of a particle-based ISTD within the LDIR workflow enabled sample-specific performance assessment, addressing a key limitation in current microplastic methodologies. Application to environmental samples confirmed the robustness of the approach and highlighted the capability of the 8700 LDIR to support high‑confidence, reproducible microplastics analysis for research and routine monitoring applications.</p><h3><strong>2. MDCW / Los Alamos National Laboratory: Discovery-based analysis for chromatographic trends using alteration analysis (ALA) and two-dimensional correlation analysis (2DCOR)</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/O_1_Freye_10783a9cf3.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>The presentation focuses on discovery-based analysis of complex chromatographic datasets using <strong>Alteration Analysis (ALA)</strong> and <strong>Two-Dimensional Correlation Analysis (2DCOR)</strong>. The motivation is to avoid manual chromatogram comparison and labor-intensive peak-table processing, especially for GC-TOFMS and GC×GC datasets that can contain billions of data points. Instead, the authors analyze raw data directly and use statistical methods to identify only those features that show meaningful chemical changes across a series of samples.</p><p>ALA provides a quantitative way to detect how individual data points vary across a sample series. It generates three outputs: the <strong>Basic Alteration Map (BAM)</strong> for overall change, the <strong>Synchronous Alteration Map (SAM)</strong> for mainly linear changes, and the <strong>Asynchronous Alteration Map (AAM)</strong> for nonlinear behavior. Validation with simulated datasets showed that ALA can detect relatively small changes and remains effective even for severely overlapping chromatographic peaks. The presentation reports that its performance remains similar to that for isolated peaks down to a resolution of about <strong>Rs 0.3</strong>, and under suitable signal-to-noise and change conditions it can still succeed at resolutions as low as <strong>Rs 0.01</strong>.</p><p>While ALA identifies which signals are changing and the type or magnitude of that change, <strong>2DCOR adds information about how those changes are related to one another</strong>. Synchronous correlation maps describe whether signals change together in the same or opposite direction, while asynchronous maps help establish sequential relationships between changes. Using Noda’s rule, the order in which chemical features respond to an external perturbation can be inferred. The combined ALA–2DCOR workflow therefore provides three key pieces of information: <strong>the significance of a change, the relationship between changing components, and the order in which those changes occur</strong>.</p><p>Extending these methods to GC×GC required additional processing because of chromatographic misalignment and the enormous size of two-dimensional datasets, with GC×GC-HRMS data reaching roughly <strong>80 billion data points</strong>. The solution presented is to divide the chromatographic space into tiles, apply ALA to locate important features, then re-center tiles and use 2DCOR on the relevant regions. In a recent application to <strong>high-explosive aging</strong>, ALA detected more than <strong>250 chemical changes</strong>, providing insight into decomposition behavior where simpler feature-selection approaches such as the F-ratio were insufficient. The authors conclude that combining ALA and 2DCOR offers a practical route for discovering and interpreting chemical trends in highly complex GC-MS and GC×GC datasets.</p><h3><strong>3. Shimadzu: Residual Solvent Analysis in Pharmaceuticals with N2 Carrier Gas Using </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=1&amp;search=GC-2060"><strong>Nexis GC-2060</strong></a><strong> and </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=1&amp;search=HS-20+NX"><strong>HS-20 NX</strong></a></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_01_01172_en_59d0e341a0.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>User benefits</strong></h4><ul><li>The newly designed FID delivers outstanding sensitivity, ensuring highly accurate and reliable analysis.</li><li>Achieve full compliance with JP and USP guidelines using N2 carrier gas, which is highly affordable and readily available.</li><li>Easily analyzes tert-butyl alcohol and Cyclopentyl methyl ether, the Class 2 solvents added in the ICH Q3C (R8) guideline.</li></ul><p>For the analysis of residual solvents in pharmaceuticals, headspace gas chromatography (HS-GC) is widely used to target Class 1 and Class 2 solvents, in accordance with USP General Chapter &lt;467&gt; and JP18 (Japanese Pharmacopoeia, 18th Edition). These regulatory tests demand high sensitivity and reproducibility. The newly developed FID for the Nexis GC-2060 offers superior detection sensitivity compared to conventional models, enabling highly sensitive analysis. Additionally, due to recent helium supply shortages and rising costs, there is a growing demand for alternative analysis using nitrogen (N2) as a carrier gas.&nbsp;</p><p>This application note presents the analysis of Class 1 and Class 2 water-insoluble samples using the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=1&amp;search=GC-2060"><strong>Nexis GC-2060</strong></a> with N2 carrier gas, compliant with Supplement II to the Japanese Pharmacopoeia. DMSO was used as the sample solvent.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>Using the Nexis GC-2060 with nitrogen (N2) carrier gas, we successfully achieved the analytical precision required by the Japanese Pharmacopoeia (JP18) and USP General Chapter &lt;467&gt;. The HS-GC method delivered excellent S/N ratios and high repeatability for the analysis of residual solvents in waterinsoluble pharmaceutical samples.</p><h3><strong>4. Thermo Fisher Scientific: Measuring and monitoring emissions at data centers: A practical guide to compliance and performance</strong></h3><ul><li>Other document (white paper)</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/datacenter_emissions_wp1802_en_45a9da8df3.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The rapid expansion of data centers, driven by artificial intelligence (AI), cloud computing, and digital infrastructure, is creating unprecedented demand for electrical power. In many regions, utility interconnection delays, transmission constraints, and the need to bring new computing capacity online quickly are driving data center developers to incorporate onsite power generation as part of their energy strategy. Natural gas-fired turbines, reciprocating engines, and other distributed generation assets are increasingly being deployed to supplement or, in some cases, serve as the primary source of power for new facilities.&nbsp;</p><p>As data centers evolve from purely electrical loads into powergenerating facilities, they become subject to a range of air permitting, emissions reporting, and regulatory compliance requirements. Consequently, emissions monitoring has emerged as a critical component of both regulatory compliance and responsible facility operation. Facility owners and operators must balance the need for reliable power generation with increasingly stringent environmental requirements while maintaining operational performance and uptime.&nbsp;</p><p>This white paper provides a practical, technically grounded overview of emissions monitoring strategies for data centers with onsite power generation. It outlines the regulatory landscape, reviews common monitoring approaches, and discusses key system design considerations to help facility owners, operators, engineers, and environmental professionals develop effective compliance strategies while supporting the continued growth of digital infrastructure.</p><h4><strong>Analyzer technology considerations for modern CEMS&nbsp;</strong></h4><p>Gas analyzers form the core of any continuous emissions monitoring system. These instruments rely on well-established measurement principles that are recognized by regulatory agencies worldwide. Chemiluminescence detection (CLD), as described in EPA Method 7E², is widely used for NOx measurement due to its sensitivity, selectivity, and long-term stability. Similarly, non-dispersive infrared (NDIR) technology, as described in EPA Method 10³, is commonly used for carbon monoxide (CO) monitoring. These proven measurement techniques are broadly accepted across federal, state, and local regulatory programs and provide the accuracy and reliability required for emissions compliance applications. Selecting analyzer platforms that are widely deployed and familiar to regulators, testing organizations, and CEMS integrators can further simplify implementation, helping facilities achieve a smoother commissioning process and faster path to compliance.&nbsp;</p><p>Within this context, modern analyzer platforms like the <strong>Thermo Scientific™ 42iQ NO-NO2-NOx Gas Analyzer </strong>and the <strong>Thermo Scientific™ 48iQ CO Gas Analyzer</strong> have been specifically designed to support continuous emissions monitoring applications. These systems deliver high sensitivity, low detection limits, and stable performance across a wide range of operating conditions. Both analyzers can also be configured with optional oxygen (O₂) measurement capability, providing a convenient and cost-effective solution for monitoring NOx , CO, and O₂. This capability is particularly valuable in direct extractive CEMS configurations, where oxygen measurements are often required for emissions correction and reporting.&nbsp;</p><p>Seamless integration with data acquisition and handling systems (DAHS) is another key requirement for a modern CEMS. Analyzer platforms must support reliable data communication and interoperability, enabling consistent reporting and alignment with regulatory requirements.&nbsp;</p><p>Selecting the appropriate analyzer technology is a critical step in CEMS design. A well-designed analyzer solution not only supports compliance, it also contributes to long-term operational efficiency, reduced lifecycle costs, and confidence in emissions data.</p></div></div></div></div></div></div></section></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 37, 2026

<p><strong>ISC 2026 officially opened in Prague on Sunday, September 6, bringing the international separation science community together at the Prague Congress Centre. The first day began with six Short Courses covering topics from analytical procedure lifecycle and mass spectral interpretation to HILIC, oligonucleotides, LC/MS data analysis, and supercritical fluids. In the afternoon, conference chairs Michal Holčapek and Lucie Nováková welcomed participants during the Opening Ceremony, followed by the J.F.K. Huber Medal Award Ceremony. The scientific program then moved into its first plenary session, spanning spintronics, single-cell proteomics and robust LC-MS, and rapid evaporative ionisation mass spectrometry. The opening day concluded with the Welcome Reception, giving participants their first opportunity to meet colleagues from around the world and begin a week of scientific exchange, new ideas, and chromatography in the heart of Prague.</strong></p><h4><strong>Sunday, September 6th</strong></h4><h5><span><strong>8:30–15:45 Short Courses 3 - 8</strong></span></h5><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_ISC_2026_Day_1_Short_Courses_Koen_Sandra_176f1c6d52.jpg" alt="ISC: ISC 2026 - Day 1: Short Course SC 6 Oligonucleotides and Other Biopharmaceuticals (Koen Sandra)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_ISC_2026_Day_1_Short_Courses_Koen_Sandra_176f1c6d52.jpg 235w," sizes="100vw" width="1600" height="1067"></p><h5><span><strong>16:00–16:30 Opening Ceremony</strong></span></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/lcms/articles?search=hol%C4%8Dapek"><span><strong>Michal Holčapek</strong></span></a><span>, Czech Republic</span></li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/lcms/articles?search=Lucie+Nov%C3%A1kov%C3%A1"><span><strong>Lucie Nováková</strong></span></a><span>, Czech Republic</span></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_ISC_2026_Day_1_Opening_Novakova_and_Holcapek_bbf9dd44e3.jpg" alt="ISC: ISC 2026 - Day 1: Michal Holčapek and Lucie Nováková opened ISC 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_ISC_2026_Day_1_Opening_Novakova_and_Holcapek_bbf9dd44e3.jpg 235w," sizes="100vw" width="1600" height="1067"></p><h5><span><strong>16:30–17:00 Award Ceremony</strong></span></h5><ul><li>J.F.K. Huber Medal (awarded by the Austrian Society for Analytical Chemistry)</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_ISC_2026_Day_1_JFK_Huber_Award_winner_Dave_846f6a5dff.jpg" alt="ISC: ISC 2026 - Day 1: Davy Guillarme as a 2026 recipient of the J.F.K. Lecture Award of the Austrian Society of Analytical Chemistry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_ISC_2026_Day_1_JFK_Huber_Award_winner_Dave_846f6a5dff.jpg 235w," sizes="100vw" width="1600" height="1066"></p><h4><strong>Plenary lectures</strong></h4><h5><strong>17:00 - 17:30 Spintronics: A new paradigm in digital bits</strong></h5><ul><li>Tomáš Jungwirth, Czech Republic&nbsp;&nbsp;&nbsp;&nbsp;</li></ul><p>Besides the rapid developments in the big world of cloud data centers and AI, a remarkable paradigm shift is occurring on the level of the smallest “elementary particle” of information technologies – the single physical bit. For the first time in the history of microprocessor chips, semiconductor bits are being replaced by a fundamentally distinct technology. The technology is based on magnets and is called spintronics. All major developers and manufacturers of the advanced chip technologies are now implementing these new spintronic bits. Not across the entire microprocessor chip, but in some of its vital memory parts. The transition to the spintronic bits is happening because further miniaturization of semiconductor bits has become prohibitively expensive or even reached fundamental physical limits. In the talk we will introduce the distinct physical principle behind the spintronic bits, and highlight some of the recent adbances in spintronics research and development.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_ISC_2026_Day_1_Tomas_Jungwirth_dd6eeca2b5.jpg" alt="ISC: ISC 2026 - Day 1: Spintronics: A new paradigm in digital bits (Tomáš Jungwirth, Czech Republic)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_ISC_2026_Day_1_Tomas_Jungwirth_dd6eeca2b5.jpg 245w," sizes="100vw" width="1595" height="1008"></p><h5><strong>17:30 - 18:00 Single cell proteomics requires robust LC-MS: Unexpected findings bring new biological understanding</strong></h5><ul><li>Jennifer Van Eyk, USA&nbsp;&nbsp;&nbsp;&nbsp;</li></ul><p>Underlying precision medicine is the concept that an individual’s Omic signature (including the proteome) will provide a physician with clinically actionable diagnosis and a subsequent mechanistic therapeutic route that is appropriate for a particular person. This concept is based on the idea of pathological heterogeneity and recognizes the impact of differences in the heath state of individuals. The deployment of single cell technologies has demonstrated heterogeneity within a single cell type which impacts the degree of cellular heterogeneity within an organ. Unlike bulk proteomic approaches, which average signals across heterogeneous populations, single-cell proteomics captures the molecular diversity of cell. Today single-cell proteomics can provide high-resolution characterization of protein quantities and variability within the structural composition and signaling dynamics within individual cells which requires robust, precise and sensitive liquid chromatography and mass spectrometry (LC-MS) workflows with sufficient throughput to quantitatively analyze 1000s of single cells.</p><p>We have developed stable and precise single cell LC-MS workflow based on high-flow, dual trap with a single analytical column system that can achieve 96 samples per day. Furthermore, we have coupled this with a novel parallel sample preparation method on demand within the autosampler reducing sample lose and matching throughput with the LC-MS. Here, we have investigated the proteomic heterogeneity of cardiac muscle cells, cardiomyocytes, the specialized cells that contain the contractile proteins and which are responsible for the heart contraction and relaxation. By applying single-cell proteomics to cardiomyocytes isolated from human and mouse hearts, as well as human iPSC-derived cardiomyocytes, we uncovered previously unrecognized cellular subpopulations distinguished by differences in contractile and metabolic protein expression. As well unexpectedly, we unambiguously identified proteins traditionally considered absent in adult cardiomyocyte, such as slow skeletal troponin T, previously thought to be restricted to fetal or skeletal muscle or those proposed to be limited to non-cardiac cell types (e.g., neuronal proteins) or species (e.g., myosin heavy chain 7b). This suggests an unexpected fluidity in cardiac protein expression. Furthermore, single cell proteomics has provided critical insight into protein-level remodeling in heart failure, where the same single amino acid mutation in a contractile protein can give rise to diverse clinical phenotypes. At the single cell level, the mutant protein dosage in each cell drives a continuum of subproteomic pathological alterations. Only with precise protein quantification at the single cell level, is this understanding possible – all of which hinges on the LC-MS performance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_ISC_2026_Day_1_Jennifer_Van_Eyk_f8641196ff.jpg" alt="ISC: ISC 2026 - Day 1: Single cell proteomics requires robust LC-MS: Unexpected findings bring new biological understanding (Jennifer Van Eyk, USA)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_ISC_2026_Day_1_Jennifer_Van_Eyk_f8641196ff.jpg 235w," sizes="100vw" width="1600" height="1066"></p><h5><strong>18:00 - 18:30 Rapid evaporative ionisation mass spectrometry: From MSI to LC-MS</strong></h5><ul><li>Zoltan Takats, United Kingdom&nbsp;&nbsp;&nbsp;&nbsp;</li></ul><p>Rapid Evaporative Ionisation Mass Spectrometry (REIMS) was originally developed for mass spectrometry-guided surgery applications, enabling the direct, real-time analysis of surgical aerosols for in-situ histological identification of tissues in cancer surgery. Coupling the technique with various surgical and non-surgical lasers led to the recognition, that the technique has comparable sensitivity to other, widely used desorption ionisation methods including DESI and MALDI. Laser Ablation REIMS using 3 μm wavelength picosecond lasers was demonstrated to provide sub-cellular resolution metabolic and lipidomic images at 2-5 μm spatial resolution, with clear visualisation of cellular nuclei. The method was subsequently used for regenerative neuroscience and cancer biology applications. The unexpectedly high sensitivity of the method (fg amounts of lipids and metabolites / pixel) encouraged us to attempt using REIMS as an LC-MS ion source. The current commercially available REIMS instrumentation utilises the so-called matrix-assited REIMS technology, involving the co-introduction of a polar solvent (water, acetonitrile or aliphatic alcohols) together with the sample aerosol. The fused droplets containing solvent and soluble components of the aerosol are introduced into the vacuum where they impact a heated (≈900 ºC) surface resulting in their 'rapid evaporation' yielding the detected ion population. In this context, the ionisation matrix was replaced by LC effluent, leading to a fundamentally new way of ionisation. The new technique termed LC-REIMS was characterised using reversed phase LC applications including lipid and metabolite profiling. The new ionisation method was found to exhibit high similarity to sonic spray and related techniques, in spite of the high temperature involved. Analytical sensitivity for complex lipids and amino acids were found to be comparable to those in ESI or APCI, albeit the relative response factors followed markedly different trends. As the technology represents an LC-MS coupling without any requirement for pressurised gas or high voltage, it has significant application potential for field instrumentation including industrial process control or security screening.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_ISC_2026_Day_1_Zoltan_Takats_3e0c11a22e.jpg" alt="ISC: ISC 2026 - Day 1: Rapid evaporative ionisation mass spectrometry: From MSI to LC-MS (Zoltan Takats, United Kingdom)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_ISC_2026_Day_1_Zoltan_Takats_3e0c11a22e.jpg 129w," sizes="100vw" width="1600" height="1933"></p><h5><span><strong>18:30–19:30 Welcome Reception</strong></span></h5><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_ISC_2026_Day_1_Welcome_reception_36bfcb7276.jpg" alt="ISC: ISC 2026 - Day 1: Welcome reception" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_ISC_2026_Day_1_Welcome_reception_36bfcb7276.jpg 235w," sizes="100vw" width="1600" height="1067"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_ISC_2026_Day_1_Welcome_reception_2_4ae69091a6.jpg" alt="ISC: ISC 2026 - Day 1: Welcome reception" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_ISC_2026_Day_1_Welcome_reception_2_4ae69091a6.jpg 235w," sizes="100vw" width="1600" height="1067"></p>

ISC 2026 - Day 1

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Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

BaySpec DBDI Ionization Source

BaySpec DBDI is a versatile plasma-based ambient ionization source for portable MS, enabling soft, gas-free analysis of vapors and gases with minimal fragmentation and real-time results.

<h4><strong>Ambient Ionization Sources for Portable Mass Spectrometers</strong></h4><p>BaySpec offers many types of ionization sources to use with our <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2219"><strong>Portability™</strong></a><strong> </strong>and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2218"><strong>Continuity™</strong></a> portable mass spectrometers. Delivering ultimate mobility and ease of use, BaySpec’s Portability™ and Continuity™ are compatible with ambient ionization techniques, which do not require any gases or tanks to run measurements. Making it ideal for field analysis, ambient ionization does not require sample preparation; sample introduction quick, direct, and easy to perform by anyone in any location. Providing flexibility to perform applications using various ionization techniques, the external ionization sources can also easily be swapped in less than a minute.</p><h4><strong>Key Features</strong></h4><ul><li>TD-ESI, ESI, TD-APCI, Swab-APCI, APCI, DBDI, and more</li><li>Ambient Ionization</li><li>No Tanks or External Pumps</li><li>No Sample Prep</li><li>Swappable</li><li>Field Analysis Ready</li><li>Real-time Results</li><li>Vapors, Liquids, Solids</li></ul><h4><strong>Dielectric Barrier Discharge Ionization (DBDI)</strong></h4><p>Versatile plasma-based ion source designed for analyzing small molecules with low to high polarity. This soft ionization technique minimizes in-source fragmentation and requires no auxiliary gas supply, making it best suited for vapor and gas samples. An optional thermal desorber enhances the sample coverage.</p>

BaySpec Multimodal Ionization Source

BaySpec Multimodal Ionization combines plasma and corona discharge ionization to expand analyte coverage, reduce noise, and deliver flexible ambient MS analysis of vapors and gases.

<h4><strong>Ambient Ionization Sources for Portable Mass Spectrometers</strong></h4><p>BaySpec offers many types of ionization sources to use with our <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2219"><strong>Portability™</strong></a><strong> </strong>and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2218"><strong>Continuity™</strong></a> portable mass spectrometers. Delivering ultimate mobility and ease of use, BaySpec’s Portability™ and Continuity™ are compatible with ambient ionization techniques, which do not require any gases or tanks to run measurements. Making it ideal for field analysis, ambient ionization does not require sample preparation; sample introduction quick, direct, and easy to perform by anyone in any location. Providing flexibility to perform applications using various ionization techniques, the external ionization sources can also easily be swapped in less than a minute.</p><h4><strong>Key Features</strong></h4><ul><li>TD-ESI, ESI, TD-APCI, Swab-APCI, APCI, DBDI, and more</li><li>Ambient Ionization</li><li>No Tanks or External Pumps</li><li>No Sample Prep</li><li>Swappable</li><li>Field Analysis Ready</li><li>Real-time Results</li><li>Vapors, Liquids, Solids</li></ul><h4><strong>Muiltimodal Ionization</strong></h4><p>Combined plasma-based and corona discharge-based ionization, allowing for a greater coverage of analytes. This patented technology improves ion generation and reducing noise. Can be operated in combined, DBDI only, or APCI only mode, offering versatility for different analytical needs. It is best suited for the analysis of vapor and gas samples but an optional thermal desorber extends its capabilities to solid and liquid samples.</p>

BaySpec PI Ionization Source

BaySpec PhotoIonization (PI) uses low-energy UV photons to selectively ionize analytes with minimal chemical noise, ideal for sensitive field analysis of pesticides and steroids.

<h4><strong>Ambient Ionization Sources for Portable Mass Spectrometers</strong></h4><p>BaySpec offers many types of ionization sources to use with our <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2219"><strong>Portability™</strong></a><strong> </strong>and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2218"><strong>Continuity™</strong></a> portable mass spectrometers. Delivering ultimate mobility and ease of use, BaySpec’s Portability™ and Continuity™ are compatible with ambient ionization techniques, which do not require any gases or tanks to run measurements. Making it ideal for field analysis, ambient ionization does not require sample preparation; sample introduction quick, direct, and easy to perform by anyone in any location. Providing flexibility to perform applications using various ionization techniques, the external ionization sources can also easily be swapped in less than a minute.</p><h4><strong>Key Features</strong></h4><ul><li>TD-ESI, ESI, TD-APCI, Swab-APCI, APCI, DBDI, and more</li><li>Ambient Ionization</li><li>No Tanks or External Pumps</li><li>No Sample Prep</li><li>Swappable</li><li>Field Analysis Ready</li><li>Real-time Results</li><li>Vapors, Liquids, Solids</li></ul><h4><strong>PhotoIonization (PI)</strong></h4><p>Uses high-intensity, low-energy UV photons to ionize analytes, reducing chemical noise as common solvents and air components remain non-ionized. It is particularly effective for molecules such as pesticides and steroids with lower ionization energies. No auxiliary gas is needed, and a thermal desorber can be used to process solid or liquid samples.</p>

BaySpec Custom Ionization Source

BaySpec Customized Ionization Solutions deliver tailor-made ambient ion sources to meet specific experimental and industrial needs, ensuring optimal performance for diverse sample types.

<h4><strong>Ambient Ionization Sources for Portable Mass Spectrometers</strong></h4><p>BaySpec offers many types of ionization sources to use with our <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2219"><strong>Portability™</strong></a><strong> </strong>and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2218"><strong>Continuity™</strong></a> portable mass spectrometers. Delivering ultimate mobility and ease of use, BaySpec’s Portability™ and Continuity™ are compatible with ambient ionization techniques, which do not require any gases or tanks to run measurements. Making it ideal for field analysis, ambient ionization does not require sample preparation; sample introduction quick, direct, and easy to perform by anyone in any location. Providing flexibility to perform applications using various ionization techniques, the external ionization sources can also easily be swapped in less than a minute.</p><h4><strong>Key Features</strong></h4><ul><li>TD-ESI, ESI, TD-APCI, Swab-APCI, APCI, DBDI, and more</li><li>Ambient Ionization</li><li>No Tanks or External Pumps</li><li>No Sample Prep</li><li>Swappable</li><li>Field Analysis Ready</li><li>Real-time Results</li><li>Vapors, Liquids, Solids</li></ul><h4><strong>Customized Solutions</strong></h4><p>For applications requiring specialized solutions, we provide custom ionization sources designed to meet specific experimental and industrial demands. Our expert team develops bespoke modules that enhance your analytical capabilities, ensuring optimal performance and precise, targeted investigations for a variety of sample types, whether you’re expanding your current setup or integrating into new equipment.</p>

Organomation RapidVap N2 Nitrogen Evaporator

The RapidVap N₂ nitrogen evaporator enables fast solvent evaporation using a controlled nitrogen stream. It combines dry block heating, vortex motion, and end-point detection for efficient sample concentration.

<p><strong>The RapidVap N₂ Evaporation Systems provide a fast, automated alternative to </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1904"><strong>Kuderna-Danish</strong></a><strong> and rotary evaporators, compatible with a wide range of aggressive chemicals. By directing a controlled stream of nitrogen or dry gas onto the sample surface, these systems reduce the partial pressure above the liquid to accelerate evaporation, with optional vortex motion and dry heat for further speed.&nbsp;</strong></p><p>The main block accommodates<strong> eight large samples up to 450 mL </strong>each, and an accessory block supports <strong>eight 170 mL tubes</strong> for solid phase extraction.&nbsp;</p><p>The unique <strong>Cool-Zone block</strong> design slows evaporation after the end point, preventing samples from going completely dry and allowing time for solvent exchange or removal. Built-in alarms notify users when the process reaches the timed end point or approaches completion, enabling unattended operation.&nbsp;</p><ul><li><strong>Dry Block:</strong> Dry heating system prevents potential contamination source</li><li><strong>Increased Surface Area: </strong>Vortex motion increases surface area for faster evaporation</li><li><strong>PTFE-Coated Chamber: </strong>Aluminum with PTFE coating for broad range of chemical compatibility</li><li><strong>End-Point Detection:</strong> Signal completion of run allows samples to be left unattended while drying to desired end point</li></ul><p><i>In partnership with <strong>Labconco</strong>.</i></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_Rapid_Vap_N2_Nitrogen_Evaporator_2_eb75d729d4.jpg" alt="Organomation RapidVap N2 Nitrogen Evaporator " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_Rapid_Vap_N2_Nitrogen_Evaporator_2_eb75d729d4.jpg 235w," sizes="100vw" width="1152" height="764"></p><h3><strong>STANDARD FEATURES</strong></h3><ul><li>Dry block heating system prevents adding potential contamination source</li><li>Vortex action, heat, and vacuum combine to accelerate evaporation</li><li>PTFE-coated chamber for broad range of chemical compatibility</li><li>Microprocessor-controlled vortex motion increases surface area for faster evaporation</li><li>Signal completion of run allows samples to be left unattended while evaporation to desired end point</li><li>Microprocessor-controlled nitrogen blow down manifold to facilitate liquid to gas phase change</li></ul><h3><strong>REQUIREMENTS (not included):</strong></h3><ul><li>Glassware</li><li>Nitrogen source with flow rate of 0.6 CFM/17 LPM minimu</li><li>Gas pressure regulator</li></ul><h3><strong>OPTIONS</strong></h3><ul><li>RS-232 Link for two-way communication (Cat# LC-7910010)</li></ul><h3><strong>SPECIFICATIONS</strong></h3><ul><li><strong>Instrument</strong>: RapidVap N2</li><li><strong>Instrument Catalog Number</strong>: LC-7910000</li><li><strong>Bath Type</strong>: Dry aluminum blocks</li><li><strong>Number of Sample Positions</strong>: Up to 8</li><li><strong>Dimensions (w x d x h)</strong>: 21.7 x 19.0 x 13.5 in</li><li><strong>Weight</strong>: Net: 99 lbs. (45 kg)</li><li><strong>Weight</strong>: Gross: 107 lbs. (49 kg)</li><li><strong>Sample Layout</strong>: Circular</li><li><strong>Lid Material</strong>: Glass</li><li><strong>Pressure Regulator</strong>: 0–20 psi</li><li><strong>Temperature Range</strong>: 0–100 °C</li><li><strong>Warranty</strong>: 1 year</li><li><strong>Electrical Requirements</strong>: 115V, 60 Hz</li><li><strong>Vortex Motion</strong>: Up to 500 RPM</li></ul><h5><strong>Nitrogen Requirements</strong></h5><ul><li><strong>Flow Rate</strong>: 0.6 CFM / 17 LPM minimum</li><li><strong>Pressure</strong>: 5–10 psi</li></ul><h3><strong>ACCESSORIES</strong></h3><ul><li>PTFE-coated aluminum blocks</li><li>Borosilicate glass tubes</li><li>600 mL tubes with stems</li><li>170 mL tubes with stems</li><li>Flat bottom tubes</li><li>Eight-place stainless steel racks</li><li>Glassware caps</li></ul>

Organomation RapidVap N2/48 Nitrogen Evaporator

The RapidVap N₂/48 Nitrogen Evaporation System rapidly concentrates up to 48 samples using nitrogen blowdown, vortex motion, and dry block heating without the need for water baths.

<p><strong>The RapidVap N₂/48 Evaporation System combines nitrogen blowdown, vortex motion, and controlled heat to accelerate evaporation of up to 48 small samples or eight 450 mL samples simultaneously. A stream of nitrogen or dry gas reduces the partial pressure over the liquid, speeding solvent removal, while microprocessor-controlled vortex motion increases surface area and continuously mixes samples for maximum recovery.&nbsp;</strong></p><p>Nitrogen delivery can be applied to<strong> 2, 4, 6, or all 8 clusters of six ports</strong>, conserving gas when processing fewer samples. Using a <strong>dry block heating method</strong>, the RapidVap N₂/48 offers a reliable, low-maintenance alternative to water bath systems and is ideal for applications such as <strong>drug development, bioresearch, combinatorial chemistry, environmental testing, forensics, and toxicology</strong>.&nbsp;</p><ul><li><strong>Dry Block:</strong> Dry heating system prevents potential contamination source</li><li><strong>Increased Surface Area: </strong>Vortex motion increases surface area for faster evaporation</li><li><strong>PTFE-Coated Chamber: </strong>Aluminum with PTFE coating for broad range of chemical compatibility</li><li><strong>End-Point Detection:</strong> Signal completion of run allows samples to be left unattended while drying to desired end point</li></ul><p><i>In partnership with <strong>Labconco</strong>.</i></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_Rapid_Vap_N2_48_Nitrogen_Evaporator_2_cc454a8f2d.jpg" alt="Organomation RapidVap N2_48 Nitrogen Evaporator" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_Rapid_Vap_N2_48_Nitrogen_Evaporator_2_cc454a8f2d.jpg 234w," sizes="100vw" width="1169" height="783"></p><h3><strong>STANDARD FEATURES</strong></h3><ul><li>Dry block heating system prevents adding potential contamination source</li><li>Vortex action, heat, and vacuum combine to accelerate evaporation</li><li>PTFE-coated chamber for broad range of chemical compatibility</li><li>Microprocessor-controlled vortex motion increases surface area for faster evaporation</li><li>Signal completion of run allows samples to be left unattended while evaporation to desired end point</li><li>Microprocessor-controlled nitrogen blow down manifold to facilitate liquid to gas phase change</li></ul><h3><strong>REQUIREMENTS (not included)</strong></h3><ul><li>Sample block</li><li>Glassware</li><li>Nitrogen source with flow rate of 3.5 CFM/100 LPM minimu</li><li>Gas pressure regulator</li></ul><h3><strong>OPTIONS</strong></h3><ul><li>RS-232 Link for two-way communication (Cat# LC-7910014)</li></ul><h3><strong>SPECIFICATIONS</strong></h3><ul><li><strong>Instrument</strong>: RapidVap N2/48</li><li><strong>Instrument Catalog Number</strong>: LC-7910012</li><li><strong>Bath Type</strong>: Dry aluminum blocks</li><li><strong>Number of Sample Positions</strong>: Up to 48</li><li><strong>Dimensions (w x d x h)</strong>: 21.7 x 19.0 x 13.5 in</li><li><strong>Weight</strong>: Net: 92 lbs. (42 kg)</li><li><strong>Weight</strong>: Gross: 100 lbs. (45 kg)</li><li><strong>Sample Layout</strong>: Circular</li><li><strong>Lid Material</strong>: Glass</li><li><strong>Pressure Regulator</strong>: 0–20 psi</li><li><strong>Temperature Range</strong>: 0–100 °C</li><li><strong>Warranty</strong>: 1 year</li><li><strong>Electrical Requirements</strong>: 115V, 60 Hz</li><li><strong>Vortex Motion</strong>: Up to 500 RPM</li></ul><h5><strong>Nitrogen Requirements</strong></h5><ul><li><strong>Flow Rate</strong>: 3,5 CFM / 100 LPM minimum</li><li><strong>Pressure</strong>: 5–10 psi</li></ul><h3><strong>ACCESSORIES</strong></h3><ul><li>PTFE-coated aluminum blocks</li><li>Borosilicate glass tubes</li><li>600 mL tubes with stems</li><li>170 mL tubes with stems</li><li>Flat bottom tubes</li><li>Eight-place stainless steel racks</li><li>Glassware caps</li></ul>

Organomation RapidVap Vertex Dry Evaporator

The RapidVap Vertex dry evaporator accelerates solvent evaporation for up to 50 samples using dry block heating, gentle nitrogen blowdown, and an intuitive touchscreen interface.

<p><strong>The RapidVap Vertex Dry Evaporator accelerates sample evaporation by combining efficient dry heat with gentle nitrogen blowdown, allowing laboratories to process up to 50 samples simultaneously.</strong></p><p>Its <strong>intuitive touchpad interface</strong> makes it easy to set and control both temperature and run time, and users can save up to <strong>ten custom programs</strong> to ensure consistent, repeatable workflows. Because it relies on a <strong>dry block heater</strong> rather than a traditional water bath, the system requires minimal upkeep—no distilled water, additives, or concerns about waterborne contamination.</p><p>The RapidVap Vertex is well-suited for a wide range of sample prep needs, including <strong>pharmaceutical and drug development, clinical laboratories, environmental analysis, agricultural chemistry, and forensic testing</strong>.&nbsp;</p><ul><li><strong>LCD Display:</strong> Touchscreen programming shows parameters for block, sample, and time</li><li><strong>Nitrogen Control: </strong>Each switch controls nitrogen flow to each row of five nozzles</li><li><strong>Temperature Sensor:</strong> Monitors block or sample temperature</li><li><strong>Dry heat - no water bath:</strong> Less maintenance, no rust, no condensation, and no potential source of cross contamination</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_Rapid_Vap_Vertex_Dry_Evaporator_2_c112725d7a.jpg" alt="Organomation RapidVap Vertex Dry Evaporator" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_Rapid_Vap_Vertex_Dry_Evaporator_2_c112725d7a.jpg 245w," sizes="100vw" width="1375" height="768"></p><p><i>In partnership with <strong>Labconco</strong>.</i></p><h3><strong>STANDARD FEATURES</strong></h3><ul><li>LCD display with touchscreen programming</li><li>Nitrogen control to each row of nozzles</li><li>Pressure regulator for 0 to 45 psi</li><li>Dry heat for less maintenance and no rust compared to water baths</li><li>Microprocessor-controlled heater up to 100 °C</li><li>Temperature sensor monitors block or sample temperature</li><li>Angled samples to increase surface area for faster evaporation</li></ul><h3><strong>REQUIREMENTS (not included)</strong></h3><ul><li>Aluminum block (Specific cat # depends on your tube size)</li><li>Sample tubes</li><li>Nitrogen source with a flow rate of <strong>6.5 CFM/185 LPM </strong>minimum</li></ul><h3><strong>SPECIFICATIONS</strong></h3><ul><li><strong>Instrument Catalog Number:</strong> LC-7320020</li><li><strong>Bath Type:</strong> Dry aluminum blocks</li><li><strong>Number of Sample Positions:</strong> Up to 50</li><li><strong>Dimensions (w x d x h):</strong> 20.4 x 13.0 x 12.5 in</li><li><strong>Weight:</strong> Net: 35 lbs. (16 kg)</li><li><strong>Weight:</strong> Gross: 45 lbs. (20 kg)</li><li><strong>Sample Layout:</strong> 5 rows of 10 samples</li><li><strong>Lid Material:</strong> Glass</li><li><strong>Pressure Regulator:</strong> 0–45 psi</li><li><strong>Temperature Range:</strong> 30–100 °C</li><li><strong>Warranty:</strong> 1 year</li><li><strong>Electrical Requirements:</strong> 115V, 60 Hz</li></ul><h5><strong>Nitrogen Requirements</strong></h5><ul><li><strong>Flow Rate:</strong> 6.5 CFM / 185 LPM minimum</li><li><strong>Pressure:</strong> &lt;50 psi</li></ul><h3><strong>ACCESSORIES</strong></h3><ul><li>Aluminum blocks</li></ul>

Linde REDLINE Pressure Regulators C 200/1 & C 200/2

REDLINE C 200 pressure regulators provide precise and stable gas control up to 6.0 purity, ideal for laboratory, analytical, and research applications.

<p><strong>The REDLINE C 200 series pressure regulators (models C 200/1 single-stage and C 200/2 dual-stage) are designed for precise control of non-corrosive gases with purity levels up to 6.0 (99.9999%), as well as gas mixtures containing low concentrations of corrosive components.</strong></p><p>These regulators ensure excellent pressure stability, high accuracy, and preservation of gas purity, making them ideal for demanding laboratory, analytical, and research applications.</p><p>The C 200/1 single-stage version is suitable for applications with stable inlet pressure, such as gases supplied in liquid phase. The C 200/2 dual-stage version is specifically designed for systems where inlet pressure fluctuates, ensuring highly stable outlet pressure even under changing conditions.</p><h4><span><strong>Key Features</strong></span></h4><ul><li>High precision pressure regulation for analytical applications</li><li>Suitable for high-purity gases up to grade 6.0 (99.9999%)</li><li>Excellent outlet pressure stability (especially dual-stage version)</li><li>Designed to maintain gas purity and minimize contamination</li><li>Wide range of configurable outlet pressure ranges</li><li>Flexible configuration with multiple valve and purging options</li><li>Robust and reliable design for laboratory and R&amp;D environments</li></ul><h4><span><strong>Technical Specifications</strong></span></h4><ul><li><strong>Inlet pressure:</strong> up to 230 bar</li><li><strong>Outlet pressure ranges:</strong><ul><li><i>C 200/1 (single-stage):</i> 3 / 6 / 10 / 14 / 16 / 28 / 35 / 50 / 100 / 200 bar</li><li><i>C 200/2 (dual-stage):</i> 1 / 3 / 6 / 10 / 14 bar</li></ul></li><li><strong>Gas compatibility:</strong><ul><li>Non-corrosive gases up to purity 6.0</li><li>Gas mixtures with low corrosive content</li></ul></li><li><strong>Inlet connections:</strong><ul><li>According to DIN 477 and gas specification</li></ul></li><li><strong>Outlet connections:</strong><ul><li>Compression fittings</li><li>Hose nozzles</li></ul></li></ul><h4><span><strong>Available Configurations</strong></span></h4><h5><span><strong>Models</strong></span></h5><ul><li><strong>C 200/1 (Single-stage)</strong><br>Designed for applications with stable inlet pressure</li><li><strong>C 200/2 (Dual-stage)</strong><br>Designed for fluctuating inlet pressure with maximum outlet stability</li></ul><h4><span><strong>Optional Equipment</strong></span></h4><ul><li>Shut-off valve (Type A)</li><li>Needle valve (Type B)</li><li>High-pressure side purge (Type P)</li><li>Inert/external gas purge (Type TP)</li><li>Purge manifold (Type EP)</li><li>Post-purge (Type DP – available only for C 200/2)</li></ul><h4><span><strong>Applications</strong></span></h4><ul><li>Laboratory gas supply systems</li><li>Analytical instrumentation (e.g., GC, LC, MS workflows)</li><li>Research and development environments</li><li>High-purity gas distribution systems</li><li>Any application requiring stable pressure and contamination-free gas delivery</li></ul>

Linde REDLINE Pressure Regulators C 300/1 & C 300/2

REDLINE C 300 pressure regulators provide precise and stable gas control up to 6.0 purity, ensuring reliability for laboratory, analytical, and research applications.

<p><strong>The REDLINE C 300 series pressure regulators (models C 300/1 single-stage and C 300/2 dual-stage) are designed for precise control of non-corrosive gases with purity levels up to 6.0 (99.9999%), as well as gas mixtures containing low concentrations of corrosive components.</strong></p><p>Thanks to their robust design and high-quality manufacturing, these regulators provide excellent pressure stability, accuracy, and long-term reliability. They are particularly well suited for demanding laboratory, analytical, and research applications where maintaining gas purity and consistent pressure is critical.</p><p>The C 300/1 single-stage regulator is recommended for applications with relatively stable inlet pressure, such as gases supplied in liquid phase. The C 300/2 dual-stage version is intended for systems with fluctuating inlet pressure, ensuring highly stable outlet pressure and improved control under varying operating conditions.</p><h4><span><strong>Key Features</strong></span></h4><ul><li>Precise and stable pressure regulation for analytical workflows</li><li>Compatible with high-purity gases up to grade 6.0 (99.9999%)</li><li>Dual-stage version provides superior outlet pressure stability</li><li>Designed to maintain gas purity and minimize contamination risks</li><li>Wide range of adjustable outlet pressure settings</li><li>Modular design with multiple optional valve and purge configurations</li><li>High reliability for continuous laboratory and R&amp;D operation</li></ul><h4><span><strong>Technical Specifications</strong></span></h4><ul><li><strong>Inlet pressure:</strong> up to 300 bar</li><li><strong>Outlet pressure ranges:</strong><ul><li><i>C 300/1 (single-stage):</i> 3 / 6 / 10 / 14 / 16 / 28 / 35 / 50 / 100 / 200 bar</li><li><i>C 300/2 (dual-stage):</i> 1 / 3 / 6 / 10 / 14 bar</li></ul></li><li><strong>Gas compatibility:</strong><ul><li>Non-corrosive gases up to purity 6.0</li><li>Gas mixtures with low corrosive content</li></ul></li><li><strong>Inlet connections:</strong><ul><li>According to DIN 477 and gas specification</li></ul></li><li><strong>Outlet connections:</strong><ul><li>Compression fittings</li><li>Hose nozzles</li></ul></li></ul><h4><span><strong>Available Configurations</strong></span></h4><h5><span><strong>Models</strong></span></h5><ul><li><strong>C 300/1 (Single-stage)</strong><br>Designed for applications with stable inlet pressure</li><li><strong>C 300/2 (Dual-stage)</strong><br>Designed for fluctuating inlet pressure with maximum outlet pressure stability</li></ul><h4><span><strong>Optional Equipment</strong></span></h4><ul><li>Shut-off valve (Type A)</li><li>Needle valve (Type B)</li><li>High-pressure side purge (Type P)</li><li>Inert gas purge (Type TP)</li><li>Purge manifold (Type EP)</li><li>Post-purge (Type DP – available only for C 300/2)</li></ul><h4><span><strong>Applications</strong></span></h4><ul><li>Analytical instrumentation (e.g., GC, LC, MS systems)</li><li>Laboratory gas supply systems</li><li>Research and development environments</li><li>High-purity gas distribution systems</li><li>Applications requiring precise pressure control and contamination-free gas delivery</li></ul>

Linde Synthetic Air – Gas Cylinder

Linde synthetic air in gas cylinders provides a stable and high-purity gas supply for analytical, laboratory, and calibration applications.

<p><strong>Synthetic air from </strong><span><strong>Linde</strong></span><strong>, supplied in pressurized gas cylinders, provides a reliable and consistent gas source with a precisely defined composition. It consists of a controlled mixture of oxygen (O₂) and nitrogen (N₂), eliminating the variability typically associated with ambient air.</strong></p><p>Due to its high purity and consistent composition, synthetic air is ideally suited for analytical and laboratory applications where reproducibility and accuracy are critical. The cylinder-based supply ensures safe handling and convenient integration into laboratory and industrial workflows.</p><h4><span><strong>Key Features</strong></span></h4><ul><li>Stable and precisely defined gas composition</li><li>High purity suitable for analytical applications</li><li>Eliminates variability of ambient air</li><li>Reliable gas source for calibration and measurement</li><li>Safe and convenient cylinder supply</li><li>Suitable for routine and advanced laboratory workflows</li></ul><h4><span><strong>Technical Specifications</strong></span></h4><ul><li><strong>Composition:</strong> approx. 20–21% O₂, balance N₂</li><li><strong>Supply form:</strong> pressurized steel cylinder</li><li><strong>Filling pressure:</strong> up to approx. 200 bar (depending on cylinder type)</li><li><strong>Valve:</strong> according to applicable standards and gas type</li><li><strong>Stability:</strong> constant composition independent of environmental conditions</li></ul><h4><span><strong>Applications</strong></span></h4><ul><li>Calibration and validation of analytical instruments</li><li>Gas chromatography (carrier or support gas)</li><li>Environmental analysis</li><li>Sensor and detector testing</li><li>Laboratory applications requiring controlled air composition</li></ul>

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