NIST26 includes integrated processing tools for LC-MS/MS data, but there are situations where working directly from instrument vendor software can be faster and more practical. When only a few peaks need to be evaluated, when mzML conversion is inconvenient, or when nominal-mass data are involved, spectra can be transferred directly into NIST Library Search for identification. This workflow can streamline spectral searching while still providing access to NIST high-resolution and low-resolution libraries, public MS/MS resources, and flexible search settings.<h4>When does direct transfer from vendor software make sense?</h4>NIST26 provides integrated data processing in the Chromatogram tab, including workflows for deconvolution and library searching. In many cases, this is the most comprehensive way to process LC-MS/MS datasets.However, chromatogram-based processing generally requires conversion of the original vendor data into mzML, for example using ProteoWizard/MSConvert. If a chromatogram is relatively simple, deconvolution is unnecessary, and only a small number of peaks need to be investigated, converting and processing the entire file may add unnecessary steps.In these situations, it can be more efficient to select an MS/MS spectrum directly in the original vendor software and send it to NIST Library Search.There are also other cases where direct transfer becomes particularly useful. Some proprietary data formats may not convert cleanly into mzML, while nominal-mass MS/MS data are not supported for MS/MS searching in the NIST26 Chromatogram tab. For this type of data, transferring or importing spectra into Library Search becomes the practical alternative.<h4>Which vendor software can send spectra directly to NIST?</h4>Several major instrument platforms provide direct integration with NIST Library Search.The workflow is available with software from:<ul><li>Agilent, including MassHunter and OpenLab,</li><li>Waters,</li><li>Thermo Fisher Scientific.</li></ul>Wiley KnowItAll can also import spectra into NIST Search and supports numerous vendor data formats through its own software environment.For some other platforms, direct NIST integration may not be available. In those situations, spectra can potentially be exported in text-based formats such as TXT or MSP ASCII and then imported into the Spectrum List in NIST Library Search.Direct transfer is generally more convenient because it avoids intermediate export and import steps.<h4>A practical Agilent example</h4>The workflow can be demonstrated using Agilent software.An analyst first selects the desired MS/MS region, averages the spectrum if necessary, and transfers it into the spectrum display. From there, the spectrum can be sent to NIST using the Search Using NIST MS Program command.Once properly configured, NIST automatically receives the spectrum and initiates the specified search. Before relying on this workflow, however, the import and library search parameters should be checked carefully.<h4>Setting up accurate-mass spectrum import</h4>For high-resolution MS/MS data, the first important step is found under Spectrum Import Options.Accurate-mass spectra should be imported with the appropriate number of decimal places for precursor and product ions, and the Accurate m/z spectrum type must be selected.Preserving mass accuracy is essential because one of the main advantages of HRMS library searching is the ability to distinguish candidates using precise precursor and fragment masses.Once the import settings are correct, the next step is configuring the library-search parameters.<h4>Searching without a precursor ion</h4>Depending on how the spectrum is selected or averaged in the vendor software, precursor information may not always be transferred automatically.NIST26 can still search such a spectrum using HiRes NoPrecursor mode.Alternatively, if the precursor m/z is known, it can be entered manually and the search can then include precursor information.The no-precursor approach can be convenient when quickly screening manually selected MS/MS spectra, particularly when the fragment pattern itself contains enough information to generate useful candidate matches.<h4>Setting mass tolerances</h4>For accurate-mass MS/MS searching, suitable precursor and product-ion tolerances are essential.An example configuration uses:<ul><li>20 ppm for the precursor ion</li><li>40 ppm for product ions</li></ul>These settings can be kept consistent with those used in the NIST26 Chromatogram workflow.Proper tolerance settings help balance search sensitivity with selectivity. If tolerances are too wide, more irrelevant candidates may be returned; if they are too narrow, valid matches can be missed because of normal measurement variation.<h4>Combining multiple spectral libraries</h4>One of the strengths of NIST Search is the ability to search multiple libraries simultaneously.A typical configuration can include the NIST high-resolution MS/MS library together with the NIST low-resolution tandem library.The NIST low-resolution library can participate in accurate-mass workflows because it contains the required indexing information. This is important because not every custom or older low-resolution library will necessarily be compatible with the same type of high-resolution search.Additional public resources can also be included, such as:<ul><li>MS-DIAL positive-mode libraries</li><li>MS-DIAL negative-mode libraries</li><li>MoNA LC-MS/MS</li></ul>Combining commercial and public libraries can substantially broaden spectral coverage. In the demonstrated workflow, several million spectra could be searched in a single configuration.For laboratories dealing with unusual metabolites, impurities, environmental contaminants, or compounds outside mainstream commercial libraries, this expanded search space can be particularly valuable.<h4>Structure searches require separate library selection</h4>MS/MS searching and structure searching do not necessarily use the same library selections.If structural searching is required, the appropriate structure-containing libraries must also be loaded in the corresponding Library Search settings.This distinction is easy to overlook when first configuring NIST26. A library may contain useful spectra but no associated structures, or the structure database may need to be explicitly selected before substructure or related structural searches can be performed.<h4>Automating the search</h4>Once the library and tolerance settings have been defined, Automatic Search can be enabled.This allows the spectrum transferred from vendor software to trigger a search immediately rather than requiring the user to launch it manually each time.For repeated workflows involving many manually selected peaks, this small automation can save considerable time.After the configuration has been optimized, it is useful to save it as a dedicated setup—for example, a configuration specifically designed for vendor-imported spectra.<h4>Understanding the result table</h4>NIST search results are typically ranked by score, but additional parameters can also help interpret the matches.Fields can include:<ul><li>score,</li><li>reverse score,</li><li>partial spectrum search score,</li><li>dot product,</li><li>molecular weight,</li><li>other user-selected parameters.</li></ul>The search result display can be customized by right-clicking the column headers and adding or removing fields.Although the standard score will usually remain the primary ranking criterion, alternative metrics can be useful when evaluating spectra with missing fragments, additional peaks, partial spectral overlap, or related structures.<h4>Why it can be useful to keep duplicate matches visible</h4>NIST includes a Best Matching Only option that reduces duplicate or repeated entries in the displayed results.When enabled, the software may reduce a list containing several library records of the same compound to the best representative match.This makes the result list easier to review, but it can also hide useful information.For initial evaluation, it is often preferable to leave this option disabled so that all matching spectra remain visible. Multiple spectra of the same compound may come from different collision energies, instruments, ion forms, or libraries, and reviewing these variations can provide useful confirmation.Filters can always be applied later once the analyst understands the full result set.<h4>Visual comparison of unknown and library spectra</h4>NIST Library Search provides several complementary views of each candidate.The experimentally acquired unknown spectrum is displayed together with the selected library spectrum, while a head-to-head spectral comparison provides an immediate visual representation of matching and non-matching ions.This is important because library-search scores should not be treated as a fully automated identification decision.A strong match should still be examined visually, especially when dealing with complex spectra, low-abundance fragments, co-isolated ions, or compounds with closely related structural analogues.The combination of numerical scoring and visual inspection provides a stronger basis for interpretation.<h4>An important issue with the Intensity Threshold setting</h4>One practical software issue deserves particular attention when importing high-resolution spectra.The Spectrum Import Options window includes an Intensity Threshold function that can remove low-intensity signals and reduce spectral noise.In principle, this would be useful. However, when an intensity threshold is applied, imported high-resolution spectra may lose their decimal mass information and be transferred as nominal-mass spectra instead.An accurate-mass peak such as 176.0815 could therefore appear simply as m/z 176.For HRMS users, this effectively removes one of the most important dimensions of the data and can compromise accurate-mass searching.Until this behavior is corrected, the safer approach is to avoid using the Intensity Threshold option during high-resolution spectrum import and perform any necessary filtering elsewhere.<h4>A related display issue in the Chromatogram window</h4>A second software behavior concerns how Spectrum Import Options are reflected in the Chromatogram tab.If the decimal precision is set to zero for importing low-resolution spectra, the head-to-head spectral display may subsequently show masses truncated according to those settings.Importantly, this is a display issue only.It does not change the accurate-mass deconvolution results or the library-search table. The underlying processed data remain unaffected; only the visual comparison at the top of the Chromatogram window reflects the altered import settings.Understanding this distinction can prevent users from mistakenly assuming that accurate-mass data have been lost from the processed results.<h4>When direct vendor-to-NIST searching is most useful</h4>Direct transfer from vendor software is not intended to replace the complete NIST26 Chromatogram workflow.Instead, it provides a complementary route for situations where full chromatographic processing is unnecessary or unavailable.It can be particularly effective when:<ul><li>only a few peaks need identification,</li><li>deconvolution is not required,</li><li>mzML conversion adds unnecessary processing,</li><li>vendor files cannot be converted reliably,</li><li>nominal-mass MS/MS spectra need to be searched,</li><li>spectra have already been reviewed and selected in the vendor environment.</li></ul>For these cases, direct spectrum transfer offers a fast route from the original MS/MS data to spectral library identification.<h4>Connecting vendor software with broader NIST26 capabilities</h4>The workflow also illustrates a broader advantage of NIST26: analysts do not have to choose between the instrument vendor's software and an independent spectral-search environment.Vendor software can remain the primary platform for inspecting chromatograms and selecting spectra, while NIST provides access to large commercial libraries, public MS/MS databases, flexible scoring, spectral comparison, and additional interpretation tools.Used together, these environments can provide a practical workflow for both rapid routine searching and more detailed unknown identification.The key is careful configuration. Accurate-mass import settings, mass tolerances, library selection, search mode, and result-display options all influence how effectively the workflow performs.Once these parameters are properly established and saved, sending a spectrum from the vendor software to NIST26 can become a rapid and repeatable part of everyday LC-MS/MS data interpretation.

Sending MS/MS (Tandem) Spectra to NIST26 Search

UCTP-REFINE Lab is a research group at the University of Chemistry and Technology Prague focused on sustainable waste valorization, chemical recycling, and the production of alternative feedstocks for chemicals and fuels. The team combines chemical engineering, catalysis, and advanced analytical chemistry to study the thermal and catalytic conversion of complex waste streams, particularly plastics, tires, and biomass, including pyrolysis and upgrading of resulting oils. A strong emphasis is placed on comprehensive characterization of feedstocks, intermediates, and products to link composition and process conditions with product quality and support the development of circular, resource-efficient technologies.<h3>PhD position Chemometric processing of GC×GC data from alternative fuels and oils produced via thermochemical conversion of biomass and plastics</h3><h4>Expected experience:</h4><ul><li>Master's degree in chemistry or chemical engineering</li><li>Strong background in analytical chemistry and chemistry in general; a background in chemical engineering is beneficial</li><li>Experience with chromatography is mandatory.</li><li>Experience with chemometric data processing (e.g. in Python) and GC×GC is not required but is beneficial.</li><li>Top-level English, both spoken and written, ideally proven by a certificate.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/refine_lab_equipment_33ff27095e.jpg" alt="UCTP-REFINE-lab: Process Gas Chromatograph with Electrolyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_refine_lab_equipment_33ff27095e.jpg 208w," sizes="100vw" width="500" height="375"><h4>Expected work:</h4><ul><li>Close collaboration with all involved colleagues and relevant partners from the project consortium.</li><li>GC×GC analysis of complex samples utilizing FID, MS and NCD detectors.</li><li>The focus will be on alternative fuels and oils from thermochemical depolymerisation of biomass and plastics, as well as the samples after hydrotreating.</li><li>Advanced GC×GC data processing using chemometrics for prediction model development.</li><li>Participation also in sample production.</li><li>Contribution to project reports, publications, and conference presentations.</li></ul><h4>What we offer:</h4><ul><li>A young but fast-growing Team with strong international collaborations with academia and industry.</li><li>Top-level facilities and expertise in hydrotreating and liquid product analysis.</li><li>Work on a prospective topic in close collaboration with top EU companies as part of a demonstration EU project.</li><li>Competitive income, which level depends entirely on your activity and productivity.</li></ul>Questions? Feel free to contact our students Adham (yaghia@vscht.cz) or Vít (vyskocit@vscht.cz).<ul><li>Preferred start: early 2027</li><li>Application deadline: 30th October 2026</li><li>Funding: Fully funded PhD position as part of an upcoming HE project.</li></ul>If you are interested and meet the criteria, apply through the application form below.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://www.uctp-refine-lab.com/joining-our-team-form-gcxgc">Apply through this form</a></blockquote>

PhD position Chemometric processing of GC×GC data from alternative fuels and oils

The integrity of sport depends on the ability to detect prohibited substances accurately, reliably and with confidence. However, as doping strategies become increasingly sophisticated, the analytical demands placed on anti-doping laboratories continue to evolve.Today’s laboratories must do more than test for a static list of known compounds. They need broad analytical strategies capable of addressing hundreds of substances across multiple chemical classes, identifying emerging threats and supporting defensible confirmation and reporting of adverse analytical findings. For more than 25 years, Thermo Fisher Scientific has worked globally with World Anti-Doping Agency (WADA)-accredited laboratories to advance the analytical science supporting modern anti-doping programs.<h3>Anti-doping testing is a moving target</h3>The World Anti-Doping Agency publishes an annually updated Prohibited List that provides a global framework for testing programs. Yet the list is non-exhaustive, meaning laboratories may also need to detect structurally related compounds and substances across several categories, with similar chemical structure and biological activity. That creates a significant analytical challenge. Anti-doping laboratories must be prepared to monitor a broad range of compounds while maintaining the sensitivity, specificity, and confidence required for both initial testing and confirmation. At the same time, the landscape continues to change. Emerging substances, rapidly expanding doping strategies and new approaches to sample collection and analysis are creating multiple considerations for anti-doping laboratories to consider. Dried blood spots (DBS), for example, have gained attention as a complementary approach to traditional urine and venous blood collection supporting applications such as detecting steroid esters and monitoring peptides. High-resolution mass spectrometry is also enabling laboratories to consider both targeted analysis and retrospective interrogation of previously acquired data as scientific knowledge and regulations evolve.<h3>From screening to confident confirmation</h3>No single analytical technique can address every anti-doping challenge.With respect to chemical analysis of toxicologically relevant compounds, modern doping control laboratories employ complementary technologies—including liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS) and isotope ratio mass spectrometry (IRMS)—depending on the compounds and analytical questions involved.For initial testing, laboratories may need to efficiently screen biological samples for numerous prohibited substances spanning categories such as steroids, stimulants, metabolic modulators, diuretics, narcotics, cannabinoids and peptides.When &nbsp;an initial Testing Procedure produces a result requiring confirmation, laboratories need analytical approaches capable of supporting confident confirmation.This combination of broad screening and targeted confirmation has made mass spectrometry central to modern anti-doping science.<h3>Expanding possibilities with LC-MS</h3>High-resolution accurate-mass mass spectrometry can provide precise mass measurements while supporting comprehensive screening of known and suspected substances, while preserving information-rich data that can support investigation of emerging or previously untargeted compounds.An important advantage of high-resolution mass spectrometry is the ability to revisit previously acquired data. As new substances, metabolites or other analytical targets are identified, laboratories can potentially re-process previously acquired full scan data (and any corresponding MSn experiment) without reanalyzing the original sample. This strategy is currently used by laboratories to support global re-testing programs.&nbsp; Triple quadrupole <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/lcms/products?category=20&amp;manufacturerItems=3">LC-MS</a> can complement these workflows by supporting sensitive, targeted quantitation and confirmation of prohibited substances.Together, these approaches provide laboratories the flexibility needed to address today’s testing requirements while giving laboratories greater flexibility to respond to emerging analytical challenges.<h3>The continuing role of GC-MS/MS</h3>Gas chromatography coupled with triple quadrupole mass spectrometry remains an important technology in anti-doing laboratories, particularly for urinary steroid profiling and the screening and confirmation of anabolic- &nbsp;androgenic steroids and other GC-amenable prohibited substances.GC-MS/MS can support both screening and confirmation while providing the sensitivity, selectivity and dymanic range required for screening and confirmatory analysis.The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/485">Thermo Scientific TSQ 9610 Triple Quadrupole GC-MS</a> is designed to maximize sample throughput, helping laboratories address the demands of routine testing while maintaining analytical performance across a wide dynamic range. &nbsp;The TSQ 9610 incorporates NeverVent technology, designed to increase instrument uptime by reducing the disruption associated with routine source maintenance.As anti-doping workflows evolve, bridging screening and confirmation together within robust analytical strategies can help laboratories respond efficiently to increasingly complex testing requirements.<h3>When identifying a steroid isn’t enough</h3>In some anti-doping investigations, simply detecting a compound does not provide the complete answer.Testosterone, for example, can be produced naturally by the body or administered externally as an anabolic steroid. In cases where laboratories need to distinguish between endogenous and exogenous sources, isotope ratio mass spectrometry can provide another layer of information.GC-IRMS can help laboratories determine whether selected urinary steroids are consistent with an endogenous or exogenous origin by comparing carbon isotope ratios.The result is an analytical toolkit in which different technologies answer different questions—from broad screening and sensitive confirmation to determining the origin of a compound.<h3>Putting advanced workflows into practice</h3>Technology is only part of the equation. Real-world anti-doping laboratories also need to manage high sample volumes, turnaround expectations and continually changing analytical requirements.At Laboratoire Anti-Dopage Français (LADF), Director Dr. Magnus Ericsson and his team use advanced mass spectrometry workflows to support anti-doping testing.According to Ericsson, integration of <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products?category=20&amp;manufacturerItems=3">Thermo Scientific TSQ</a> and <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products?category=37&amp;manufacturerItems=3&amp;search=vanquish">Vanquish systems</a> has helped enhance efficiency and turnaround while supporting more than 40,000 sample analyses since 2023.Experiences like these demonstrate how integrated analytical workflows can help laboratories translate advances in mass spectrometry into routine anti-doping operations.<h3>Preparing for what comes next</h3>Anti-doping science has advanced dramatically—from early testing approaches to today’s sophisticated, — mass spectrometry technologies; including but not limited to <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/products?category=20&amp;manufacturerItems=3">GC-MS/MS</a>, <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/lcms/products?category=20&amp;manufacturerItems=3">LC-MS/MS</a>, <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products?category=22&amp;manufacturerItems=3">high-resolution accurate-mass MS</a> and<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/products?category=351&amp;manufacturerItems=3"> isotope ratio MS</a> workflows.But the science cannot stand still.Emerging compounds, evolving regulations and increasingly sophisticated doping strategies mean laboratories must continually evaluate how they manage and process samples and then screen, identify, quantify and confirm prohibited substances. The goal remains constant: provide accurate, high-quality analytical results that help protect the integrity of competition.Explore the technologies, workflows and expert perspectives shaping the next generation of anti-doping testing in our comprehensive eBook, Upholding the Integrity of Sport.<blockquote><h5><a target="_blank" rel="noopener noreferrer" href="https://documents.thermofisher.com/TFS-Assets/CMD/brochures/eb-004467-cl-cmd-ms-antidoping-eb004467-na-en.pdf">Download the anti-doping eBook</a></h5></blockquote>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#AntiDoping #MassSpectrometry #SportsIntegrity #WADA

Advancing Anti-Doping Science: Analytical Strategies for the Evolving Fight Against Doping

Article

Product

Application

Academy

Video

Software

Career

A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

UCTP-REFINE Lab is a research group at the University of Chemistry and Technology Prague focused on sustainable waste valorization, chemical recycling, and the production of alternative feedstocks for chemicals and fuels. 

UCTP-REFINE Lab

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.

James Little/Mass Spec Interpretation Services

Trajan Mitra Microsampling Devices - Microsample collection kit

The Microsample Collection Kit Mitra format streamlines the blood microsampling process, enabling both assisted and self-collection at home or in the field.

<h3>About</h3>The Microsample Collection Kit Mitra format streamlines the blood microsampling process, enabling both assisted and self-collection at home or in the field. Each kit is equipped with device, barcoding for secure chain of custody, easy-to-follow instructions, all necessary finger-prick sampling supplies, and a return-mailing envelope, all packaged for global distribution. Ideal for remote blood collection, these kits ensure that samples can be directly sent to accredited labs for precise analysis.For customization to meet the demands of large-scale projects or to optimize your workflows and logistics, please consult with our <a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/contact">Microsampling Consultants</a>. They will provide tailored recommendations to align with your project’s specific objectives.<h4>All-in-One Solution for Remote Specimen Collection</h4>Our Mitra devices can be packed in convenient kits with sterile components for safe sample collection. Kits can be shipped to your end-users.<ul><li>10, 20, &amp; 30 µL volumes</li><li>Protective outer casing</li><li>Barcoding to manage chain of custody</li><li>Packed in specimen bag with desiccant for transport &amp; storage</li><li>Contains devices &amp; supplies</li><li>Includes instructions for use &amp; return shipping envelope</li><li>Sized for easy global mailing</li></ul><h3>Specifications</h3><div class="tabs__tab txt--light tabs__tab--active" id="tab_1721774838869_2"><ul><li>Indication for Use: The Microsample Collection Kit is a single-use non-sterile procedure pack intended for the collection, storage and transport of capillary whole blood specimens of specified volume.</li><li>Sampler Tip Volume: 10, 20, or 30uL</li><li># of Samplers per Device: 2 or 4</li><li># Device per kit: 1/Pk</li><li>Pack content: 1x Mitra Device, 1x Specimen Bag with Desiccant, Sample ID Barcode, Lancet (x2 or x4), Gauze (x1 or x2), Bandage (x2 or x4), 1x Plastic Shipping Envelope, 1x IFU</li><li>Shelf Life: 18 months</li><li>Regulatory status: The Mitra Blood Sample Collection Kit is a procedure pack. The kits are available as registered Medical Device in the European Union and United Kingdom, Australia, Brazil, China, and Canada, as well as multiple Health Ministries worldwide. In the USA, procedure packs are supplied as a research use only (RUO) product to assist in method development, other research-related and non-diagnostic activities. End-users and laboratories must validate the use of the Mitra devices and Mitra Microsample collection kit for the particular diagnostic testing intended.</li></ul></div><h3>How to Use</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/NEOX_Content/IFUs/2023/Collection%20Kits/VLBL-0124-Rrev00.pdf">Instructions for Use (RUO)</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/NEOX_Content/IFUs/2023/Collection%20Kits/VLBL-0124rev00.pdf">Instructions for Use (MD)</a></li></ul><h3>Resources</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/NEOX_2022%20Mitra%20Collateral/Mitra%20Specification%20Sheet%20(3).pdf">Mitra Device Specification Sheet</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/Guidelines%20for%20Collecting%20Samples%20at%20Home-1.pdf">Guidelines for Collecting Samples at Home</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/NEOX_Content/Technical%20Briefs%20and%20Guidances/Long%20&amp;%20Short%20Term%20Storage%20of%20Mitra%20Samples_TG00010122.pdf">User Guide | How to Store Dried Mitra Microsamples</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/frequently-asked-questions">Frequently Asked Questions</a></li></ul><div class="tabs__tab txt--light tabs__tab--active" id="tab_1721774838869_4"><h3>Mitra devices deliver tremendous ease &amp; value to specimen collection!</h3>Mitra® Microsampling Devices offer a streamlined, flexible, and decentralized approach to biological specimen collection. Enjoy the benefits of easier trial recruitment, increased adherence / compliance, elimination of cold-chain shipping / storage &amp; reduced reliance on trained staff.<h4>The gold-standard in remote specimen collection</h4>Powered by VAMS® technology, the patented Mitra® Microsampling Device offers a streamlined, flexible, and decentralized approach to biological specimen collection, transport, and preparation. Use Mitra to facilitate sampling direct from animals, humans, or tubes to collect precise, reliable dried microsamples compatible with a wide variety of downstream applications as evidenced by the hundreds of published peer-reviewed manuscripts and the millions of devices that have been used in the field.<h4>Mitra: pioneering VAMS technology</h4>Trajan’s proprietary VAMS® Technology is at the heart of the Mitra device, featuring a sampler tip crafted from a porous, hydrophilic polymeric material. This 'precision sponge' rapidly and consistently absorbs a specific volume of biological fluid—simply by contacting the source. The fluid is then allowed to dry acting as a stabilizer for most analytes.Available in three tip sizes—10, 20, and 30 µL— and multiple formats, Mitra devices meet diverse end-user and analytical needs. Configurations include dual (2) or quad (4) samplers across various formats.&nbsp; Collect from 20 µL to 120 µL per device based on format selected. Our team of expert microsampling consultants is on hand to provide scientific support, helping you choose the optimal format and workflow for your specific applications.<ul><li>Reliable: Quantitative sampling with pipette-like precision (RSD ≤ 5%). VAMS eliminates traditional blood hematocrit biases and results in extremely low in-lab sample rejection rates. No glue used in assembly, no matrix interferences.</li><li>Versatile: Collect biological fluids—blood, plasma, urine, saliva, and even tears—efficiently from humans and animals (e.g., finger, arm, knee, tail, etc.) or containers. Manual to fully automated workflows are available.</li><li>User-Friendly: 99% sample acceptance rate validated by studies. VAMS tip acts as a fill indicator to confirm successful sampling. Outer housing protects against contamination and facilitates easy remote or home sampling.</li><li>Cost-Effective: Eliminate phlebotomy, couriers, and cold-chain shipping / storage requirements. Devices are compatible with standard automated liquid handling systems and available in various formats to suit different budgets.</li></ul><h4>Successful uses</h4>Have you seen the published, 3rd party literature of how others have successfully implemented Mitra devices?<ul><li>Preclinical</li><li>Clinical Trials / Research</li><li>Therapeutic Drug Monitoring</li><li>Omics</li><li>Biomonitoring</li><li>Toxicology</li><li>Hormones / Steroids</li><li>Biomarkers</li><li>Vitamins</li><li>Allergens</li><li>Population Screening</li><li>Infectious Diseases</li></ul></div>

Trajan Mitra Microsampling Devices - 96-autorack

The 96-Autorack™ format is designed for laboratories to efficiently batch and process Mitra microsamples using a standard 96-well format.

<h3>About</h3>The 96-Autorack™ format is designed for laboratories to efficiently batch and process Mitra microsamples using a standard 96-well format. Compatible with most 1mL &amp; 2mL collection plates and 96-channel pipettors &amp; liquid handling workstations, the 96-Autorack enhances lab productivity and integration. We provide two options: an empty 96-Autorack, perfect for accessioning microsamples from Mitra devices received from the field for building plates, extractions, and long-term storage; and prefilled 96-Autoracks with 96 Mitra samplers, ideal for method development and handling calibrators and QCs.<h4>Accession &amp; Process Multiple Mitra Samples at Once</h4>This high-throughput solution allows you to rapidly process Mitra microsamples for method development, plate building, extractions - or all of the above!<ul><li>Racks available empty or filled with 96 microsamplers (10, 20, &amp; 30 µL volumes)</li><li>Filled racks come with a 2mL deep well storage plate</li><li>Compatible with 96-channel pipettors &amp; liquid-handling workstations</li><li>Options with &amp; without barcoding</li></ul><h3>Specifications</h3><div class="tabs__tab txt--light tabs__tab--active" id="tab_17217760014256_2"><ul><li>Indication for Use: A single-use, non-sterile device used as a specimen collector, and for the storage and transport of blood and other biological fluids for analytical and diagnostic analyses.&nbsp;</li><li>Sampler Tip Volume: 10, 20, or 30uL&nbsp;&nbsp;</li><li># of Samplers per Device: 0 or 96&nbsp;</li><li># Device per pack: 1/Pk</li><li>Pack content: 1x 96-Autorack (empty or pre-filled), Sample ID Barcode, 1x Collection Plate, 1x IFU</li><li>Shelf Life: 18 months&nbsp;</li><li>Regulatory Status: Mitra® devices are CE-IVD (IVDR) devices intended as a specimen collector, and for the storage and transport of blood and other biological fluids for analytical and diagnostic analyses. They are available as registered IVD Devices in the European Union and United Kingdom, Australia, Brazil, China, and Canada, as well as multiple Health Ministries worldwide. In the USA, Mitra devices are supplied as a research use only (RUO) product to assist in method development, other research-related and non-diagnostic activities. End-users and laboratories must validate the use of the Mitra devices for the particular diagnostic testing intended.</li></ul><h3>How to Use</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/NEOX_Mitra%20IFUs/2024/VLBL-0098rev04.pdf">96-Autorack Instructions For Use (IVD)</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/NEOX_Content/IFUs/2023/96%20autorack/VLBL-0098-Rrev01.pdf">96-Autorack Instructions For Use (RUO)</a></li></ul><h3>Resources</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/NEOX_Content/User%20Guides/Mitra%20User%20Guide%20Extracting%20&amp;%20Processing%20Microsamples.pdf">User Guide | How to Extract &amp; Process Mitra Microsamples</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/NEOX_Content/Technical%20Briefs%20and%20Guidances/Long%20&amp;%20Short%20Term%20Storage%20of%20Mitra%20Samples_TG00010122.pdf">User Guide | How to Store Dried Mitra Microsamples</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/hubfs/GenTegraRNA-NEO%20for%20Mitra%20devices%20USER%20GUIDE%2011.15.23.pdf">User Guide | How to Stabilizer RNA on Mitra Microsamples with GenTegraRNA-NEO™</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.neoteryx.com/frequently-asked-questions?hsLang=en">Frequently Asked Questions</a></li></ul><h3>Mitra devices deliver tremendous ease &amp; value to specimen collection!</h3><div class="tabs__tab txt--light tabs__tab--active" id="tab_17217760014256_3"><div class="tabs__tab txt--light tabs__tab--active" id="tab_17217760014256_4">Mitra® Microsampling Devices offer a streamlined, flexible, and decentralized approach to biological specimen collection. Enjoy the benefits of easier trial recruitment, increased adherence / compliance, elimination of cold-chain shipping / storage &amp; reduced reliance on trained staff.<h4>The gold-standard in remote specimen collection</h4>Powered by VAMS® technology, the patented Mitra® Microsampling Device offers a streamlined, flexible, and decentralized approach to biological specimen collection, transport, and preparation. Use Mitra to facilitate sampling direct from animals, humans, or tubes to collect precise, reliable dried microsamples compatible with a wide variety of downstream applications as evidenced by the hundreds of published peer-reviewed manuscripts and the millions of devices that have been used in the field.<h4>Mitra: pioneering VAMS technology</h4>Trajan’s proprietary VAMS® Technology is at the heart of the Mitra device, featuring a sampler tip crafted from a porous, hydrophilic polymeric material. This 'precision sponge' rapidly and consistently absorbs a specific volume of biological fluid—simply by contacting the source. The fluid is then allowed to dry acting as a stabilizer for most analytes.Available in three tip sizes—10, 20, and 30 µL— and multiple formats, Mitra devices meet diverse end-user and analytical needs. Configurations include dual (2) or quad (4) samplers across various formats.&nbsp; Collect from 20 µL to 120 µL per device based on format selected. Our team of expert microsampling consultants is on hand to provide scientific support, helping you choose the optimal format and workflow for your specific applications.<ul><li>Reliable: Quantitative sampling with pipette-like precision (RSD ≤ 5%). VAMS eliminates traditional blood hematocrit biases and results in extremely low in-lab sample rejection rates. No glue used in assembly, no matrix interferences.</li><li>Versatile: Collect biological fluids—blood, plasma, urine, saliva, and even tears—efficiently from humans and animals (e.g., finger, arm, knee, tail, etc.) or containers. Manual to fully automated workflows are available.</li><li>User-Friendly: 99% sample acceptance rate validated by studies. VAMS tip acts as a fill indicator to confirm successful sampling. Outer housing protects against contamination and facilitates easy remote or home sampling.</li><li>Cost-Effective: Eliminate phlebotomy, couriers, and cold-chain shipping / storage requirements. Devices are compatible with standard automated liquid handling systems and available in various formats to suit different budgets.</li></ul><h4>Successful uses</h4>Have you seen the published, 3rd party literature of how others have successfully implemented Mitra devices?<ul><li>Preclinical</li><li>Clinical Trials / Research</li><li>Therapeutic Drug Monitoring</li><li>Omics</li><li>Biomonitoring</li><li>Toxicology</li><li>Hormones / Steroids</li><li>Biomarkers</li><li>Vitamins</li><li>Allergens</li><li>Population Screening</li><li>Infectious Diseases&nbsp;</li></ul></div></div></div>

LECO Tube Furnaces

LECO Cornerstone TF Tube Furnaces deliver high-temperature crucible baking up to 1350 °C, reducing contamination, improving carbon and sulfur accuracy, and cutting energy costs by up to 60%.

The LECO Cornerstone TF Tube Furnaces are versatile, energy-efficient resistance furnaces designed to bake crucibles and significantly reduce contaminants that can interfere with carbon and sulfur analytical results. Engineered for both high- and lower-volume laboratories, the TF series improves data accuracy, repeatability, and operating efficiency while reducing overall energy consumption.<h4>Key Features</h4><ul><li>Long-life molybdenum disilicide heating elements with an operating temperature range from 800 °C to 1350 °C</li><li>Integrated digital furnace controller displaying set point or actual temperature with built-in overtemperature protection</li><li>TF4 Quad Tube Furnace<ul><li>Six heating elements</li><li>Enables simultaneous baking of crucibles in four combustion tubes</li><li>Ideal for demanding, high-volume installations supporting two to four analytical units</li></ul></li><li>TF2 Dual Tube Furnace<ul><li>Four heating elements</li><li>Efficient solution for lower-volume laboratories supporting one to two systems</li></ul></li><li>Increased crucible capacity and optimized furnace design deliver up to 60% lower energy consumption compared to previous models, significantly reducing operating costs</li></ul><h4>Impact of Crucible Preheating on Analytical Results</h4>Preheating crucibles in the TF furnaces has a pronounced effect on carbon and sulfur accuracy. When 528-018 crucibles were baked at 1250 °C for 15 minutes, results for a high-purity iron reference material (certified at 5 ppm carbon and 2 ppm sulfur) showed dramatically improved accuracy and reduced variability.<ul><li>Baked crucibles produced results close to certified values with low standard deviation</li><li>Unbaked crucibles showed elevated carbon and sulfur levels</li><li>Baked but touched crucibles demonstrated significant contamination, highlighting the importance of proper handling after baking</li></ul>These results confirm that controlled crucible baking is essential for achieving low-level carbon and sulfur determinations with confidence.<h4>Energy Efficiency</h4>The redesigned TF furnaces use approximately 60% less energy than previous models. At continuous operation with a full crucible load and a furnace temperature of 1350 °C, operating cost comparisons clearly demonstrate substantial savings in power consumption, making the TF series both an analytical and economic advantage for modern laboratories.<h4>Models</h4><ul><li>TF4 – Quad Tube Furnace</li><li>TF2 – Dual Tube Furnace</li></ul>

LECO Cold Mounting Castable Mounts for Metallographic Sample Preparation

Cold mounting materials from LECO include polyester, acrylic, and epoxy resins designed for porous, brittle, or heat-sensitive samples, ensuring easy handling and excellent edge integrity.

Cold mounting—also known as castable mounting—is a metallographic sample preparation technique that uses liquid mounting media to fully encase a specimen. Common mounting materials include polyester, acrylic, and epoxy resins. After the sample is positioned in a mold, a catalyst is added to initiate curing and hardening of the mounting compound.This mounting approach is especially suitable for laboratories with lower throughput but a high diversity of samples. Cold mounting is often the preferred—or required—method for porous, brittle, irregularly shaped, or heat-sensitive specimens that cannot withstand the temperature and pressure of hot mounting. Once cured, the mounted samples are easier to handle during grinding, polishing, and analysis, while preserving edge integrity and microstructural features.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_Zalevaci_kelimky_pro_pripravu_metalografickych_vzorku_2_b63c61bea7.jpg" alt="LECO: Cold Mounting Castable Mounts for Metallographic Sample Preparation" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_Zalevaci_kelimky_pro_pripravu_metalografickych_vzorku_2_b63c61bea7.jpg 178w," sizes="100vw" width="884" height="776"><h4>Cold Mounting Media Options</h4>We offer a complete range of cold mounting materials to support different laboratory needs and sample types:<ul><li>Polyester Resins Polyesters are an economical solution for laboratories processing lower sample volumes and where edge retention is not a primary concern. They allow for fast and straightforward mounting and are well suited for routine applications requiring quick turnaround.</li><li>Acrylic Resins Acrylics cure faster than most other castable mounting materials and offer good abrasion resistance with fair edge retention. They are commonly used when multiple mounts are required and hot mounting is impractical. When used with a pressure chamber, such as the LECOMAT Pressure Vessel, acrylics can produce semi-clear mounts.</li><li>Epoxy Resins Epoxies provide hard, chemically resistant, and abrasion-resistant mounts with excellent edge retention. Although they generally require longer curing times, they offer superior flow characteristics and minimal shrinkage. Long-cure epoxies are ideal for challenging samples and can be vacuum-impregnated to remove trapped air and fill internal voids. Quick-cure epoxy formulations are also available, curing in less than one hour.</li></ul><h4>Available Products (Models)</h4><ul><li>Castolite – Polyester</li><li>LECOSET 7000 – Polyester</li><li>LECOSET 7008 – Acrylic</li><li>Quick-Cure Epoxies</li><li>Long-Cure Epoxies</li></ul><h4>Accessories and Options</h4><ul><li>Ring molds</li><li>Silicone rubber molds</li><li>Mold cups</li><li>General mounting supplies</li><li>LECOMAT Pressure Vessel for pressure impregnation and improved clarity</li></ul>

LECO DS20 Hand Grinder for Metallographic Polishing

The LECO DS20 is a compact, cost-effective benchtop hand grinder with sloped PVC platens, water flush, and integrated abrasive storage for efficient metallographic sample preparation.

The LECO DS20 Hand Grinder is a cost-effective, benchtop solution designed to simplify and streamline manual grinding during metallographic sample preparation. With a straightforward, durable design and practical workflow enhancements, the DS20 is ideal for laboratories seeking reliable surface preparation without unnecessary complexity.Engineered for ease of use and consistent results, the DS20 provides stable grinding surfaces, efficient debris removal, and integrated storage to support clean, repeatable operation in everyday lab environments.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_DS_20_Rucni_bruska_pro_metalograficke_lesteni_aa51980ffb.jpg" alt="LECO: DS20 Hand Grinder for Metallographic Polishing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_DS_20_Rucni_bruska_pro_metalograficke_lesteni_aa51980ffb.jpg 213w," sizes="100vw" width="1031" height="757"><h4>Key Features</h4><ul><li>Four sloped PVC platens providing flat, non-corroding, and well-drained grinding surfaces</li><li>Individual clamps and guides to keep abrasive paper flat during grinding</li><li>Built-in continuous water flush for effective removal of abrasive swarf</li><li>Closed storage compartment to keep abrasive rolls clean, dry, and readily accessible</li><li>Convenient abrasive paper roll system for fast changes</li><li>Supplied with silicon carbide abrasive rolls in 240, 320, 400, and 600 grit</li></ul>The DS20 is a practical choice for laboratories that value simplicity, reliability, and efficiency in manual grinding applications.

LECO BG Series Belt Grinder for Metallographic Sample Polishing

The LECO BG Series belt grinders provide durable, safe, and flexible wet or dry grinding for metallographic and spectrographic sample preparation in single- or dual-belt configurations.

The BG Series belt grinders are designed to deliver durable, safe, and convenient grinding performance for metallographic and spectrographic sample preparation. Available in both single-belt and dual-belt configurations, the BG Series supports efficient material removal while maintaining operator safety and consistent results.By combining the grinder with an optional dust collector or a recirculating system, the BG Series can be configured for either dry or wet grinding, making it a flexible solution for a wide range of laboratory workflows. Its robust construction and straightforward operation make it well suited for routine use in production, quality control, and research laboratories.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_BG_Pasova_bruska_pro_lesteni_metalografickych_vzorku_5_adfd9793f2.jpg" alt="LECO: BG Series Belt Grinder for Metallographic Sample Polishing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_BG_Pasova_bruska_pro_lesteni_metalografickych_vzorku_5_adfd9793f2.jpg 245w," sizes="100vw" width="1303" height="691"><h4>Key Features</h4><ul><li>Heavy-duty 1 HP (0.75 kW) motor for reliable and consistent grinding performance</li><li>Enclosed belt tension mechanism that prevents belt slippage and improves coolant and debris drainage</li><li>Integrated safety guards to maximize operator protection during operation</li><li>Corrosion-resistant aluminum external surfaces for long service life in laboratory environments</li></ul><h4>Available Models</h4><ul><li>BG30 – Single belt drive configuration</li><li>BG32 – Dual belt drive configuration</li></ul>

LECO SX100 Benchtop Metallographic Saw

SX100M benchtop sectioning machine delivers precise and safe cutting of metals, carbides, composites, and electronic components with a powerful motor and compact, ergonomic design.

The SX100M is an efficient benchtop sectioning machine designed to handle a wide range of materials and applications with precision and reliability. It is an ideal solution for sectioning bar stock, castings, fasteners, tungsten carbide, composite materials, electronic components, weldments, and more. With an approximate maximum sample cut diameter of 2.75 inches, the SX100M delivers dependable performance in a compact laboratory-friendly footprint.Equipped with a powerful 3 HP (2.2 kW) motor and a 10-inch (250 mm) blade capacity, the SX100M ensures consistent cutting results even for demanding materials. An integrated electronic mechanical braking system enhances operator safety and improves workflow efficiency.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_SX_100_Stolni_metalograficka_pila_83b2b057c2.jpg" alt="LECO: SX100 Benchtop Metallographic Saw" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_SX_100_Stolni_metalograficka_pila_83b2b057c2.jpg 158w," sizes="100vw" width="1185" height="1175"><h4>Key Features</h4><ul><li>Radial arm design for manual operation with an ergonomic, user-friendly working height</li><li>Base aluminum casting combined with a steel hood for durability and long service life</li><li>Integrated safety lock to protect the operator during sectioning</li><li>Built-in 6.6-gallon (25 L) recirculating coolant tank</li><li>Sloped interior floor for efficient coolant flow and reduced debris accumulation</li><li>Electronic mechanical braking system for rapid and safe blade stopping</li></ul><h4>Models</h4><h5>SX100M</h5><ul><li>Power supply options: 230 V or 400 V</li></ul>

LECO PX300 Manual Grinder/Polisher for Metallographic Sample Preparation

PX300 grinder/polisher delivers simple operation and reliable specimen preparation for microhardness and microstructural analysis, offering a compact and durable solution for low-volume metallography labs.

The PX300 Grinder/Polisher Series is designed to emphasize ease of use while consistently producing specimens that are ideal for microhardness testing and microstructural examination. Engineered as an efficient, safe, reliable, and clean solution, the PX300 is particularly well suited for lower-volume metallography laboratories that still demand high-quality, reproducible results.With a compact design and durable construction, the PX300 delivers dependable grinding and polishing performance while minimizing operator effort and routine maintenance.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PX_300_Rucni_bruska_lesticka_pro_pripravu_metalografickeho_vzorku_2_ac80a9624c.jpg" alt="LECO: PX300 Manual Grinder/Polisher for Metallographic Sample Preparation" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PX_300_Rucni_bruska_lesticka_pro_pripravu_metalografickeho_vzorku_2_ac80a9624c.jpg 244w," sizes="100vw" width="764" height="489"><h4>Key Features</h4><ul><li>Spiral bowl design with an automatic bowl wash system to prevent drain clogs and simplify cleanup</li><li>Emergency Stop button for immediate shutdown of grinding operations and enhanced operator safety</li><li>Rugged structural and electronic components designed to withstand demanding laboratory environments</li><li>Clean and reliable grinding/polishing performance suitable for routine metallographic preparation</li></ul><h5>Optional Non-Motorized Head (available at purchase or retrofit)</h5><ul><li>Enables processing of multiple samples simultaneously</li><li>Improves consistency between operators and from run to run</li><li>Enhances throughput and reproducibility in routine applications</li></ul><h4>Models</h4><ul><li><h5>PX300 (Base Model)</h5><ul><li>Power supply: 115 V or 230 V</li></ul></li><li><h5>PX300 (with Non-Motorized Head)</h5><ul><li>Power supply: 115 V or 230 V</li></ul></li></ul><h4>Options</h4><ul><li>Grinding/polishing wheel sizes:<ul><li>8 in</li><li>10 in</li><li>12 in</li><li>200 mm</li><li>250 mm</li><li>300 mm</li></ul></li></ul>

LECO PX Series Automated Metallographic Grinding and Polishing

PX400 and PX500 grinders/polishers deliver easy operation, automated workflows, and reproducible flat specimens with intuitive touch-screen control and advanced cleaning and fluid dispensing features.

The PX400 and PX500 grinders/polishers are designed to emphasize ease of use while consistently delivering exceptionally flat, high-quality specimens. Built with the latest technology, the PX Series provides an efficient, safe, reliable, and clean grinding and polishing solution that helps keep metallography laboratories running smoothly, even in high-throughput environments.With an intuitive software interface and a range of smart, operator-focused features, the PX400 and PX500 simplify daily grinding and polishing workflows while ensuring excellent reproducibility across a wide variety of materials and applications.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PX_Automatizovane_metalograficke_brouseni_a_lesteni_e46f4bd31d.jpg" alt="LECO: PX Series Automated Metallographic Grinding and Polishing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PX_Automatizovane_metalograficke_brouseni_a_lesteni_e46f4bd31d.jpg 168w," sizes="100vw" width="800" height="743"><h4>Key Features</h4><ul><li>Intuitive touch-screen software with practical tools that simplify grinding and polishing workflows</li><li>Innovative spiral bowl design with an automatic bowl wash system to prevent drain clogs and reduce cleanup</li><li>Slow wheel indexing after cycle completion for easy and safe mount removal</li><li>Individual sample mode with slow holder rotation to simplify mount loading</li><li>More than 30 proven, built-in preparation methods, with the ability to create or download additional methods</li><li>Models available for both fixed-force and individual sample preparation</li><li>Support for up to five programmable, metered fluid dispensers to deliver consistent suspensions and extenders for precise polishing results</li></ul><h4>Models</h4><ul><li><h5>PX400A (Automated)</h5><ul><li>Wheel sizes: 8 in, 10 in, 200 mm, 250 mm</li><li>Power supply: 115 V (PX400A1) or 230 V (PX400A2)</li></ul></li><li><h5>PX400S (Standard)</h5><ul><li>Wheel sizes: 8 in, 10 in, 200 mm, 250 mm</li><li>Power supply: 115 V (PX400S1) or 230 V (PX400S2)</li></ul></li><li><h5>PX500A (Automated)</h5><ul><li>Wheel sizes: 10 in, 12 in, 250 mm, 300 mm, 350 mm</li><li>Power supply: 230 V</li></ul></li></ul>

LECO MX Series Metallographic Sample Mounting Presses

MX400 and MX500 are fully automatic mounting presses with a compact design, touch-screen control, customizable methods, and dual-mount capability for fast, reliable metallographic sample preparation.

The MX400 and MX500 are fully automatic mounting presses designed to accelerate and simplify metallographic sample preparation. With a slim, space-saving 8-inch-wide footprint and an intuitive touch-screen interface, these systems deliver faster mounting cycles, higher throughput, and greater flexibility for a wide range of sample types and mounting materials.Both systems combine robust mechanical design with advanced process control, allowing laboratories to create reproducible, high-quality mounts while minimizing operator effort. The MX400 and MX500 are ideal solutions for laboratories looking to remove mounting bottlenecks and improve overall preparation efficiency.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_MX_Fixacni_lisy_pro_metalograficke_vzorky_3_8b3f6d935c.jpg" alt="LECO: MX Series Metallographic Sample Mounting Presses" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_MX_Fixacni_lisy_pro_metalograficke_vzorky_3_8b3f6d935c.jpg 193w," sizes="100vw" width="887" height="717"><h4>Key Features</h4><ul><li>Durable solid-steel crossbar closure design that resists wear, avoids jamming, and allows quick, one-handed operation</li><li>Easy-to-use swipe-and-touch user interface for intuitive selection of heating, cooling, and pressure parameters</li><li>Fully customizable mounting methods, with the option to use preconfigured LECO-developed methods</li><li>Variable operating modes optimized for delicate samples and compatible with all common mounting materials</li><li>Low thermal mass design enabling rapid heating and cooling for increased productivity</li><li>Full-size dual mounting capability to reduce bottlenecks and increase sample throughput</li><li>Supports mold sizes of 1.25 inch, 1.50 inch, 30 mm, 40 mm, and 50 mm</li><li>Quick and simple mold size changes on the MX500 model</li></ul><h4>Models</h4><ul><li><h5>MX400</h5><ul><li>Supported mold sizes: 1.25 in, 1.5 in, 30 mm, 40 mm, 50 mm</li><li>Power supply: 115 V or 230 V</li></ul></li><li><h5>MX500</h5><ul><li>Supported mold sizes: 1.25 in, 1.5 in, 30 mm, 40 mm, 50 mm</li><li>Power supply: 115 V or 230 V</li><li>Designed for rapid and easy switching between mold sizes</li></ul></li></ul>

Products from category Sample preparation - page 2

Related content

Advancing Anti-Doping Science: Analytical Strategies for the Evolving Fight Against Doping

PhD position Chemometric processing of GC×GC data from alternative fuels and oils

Sending MS/MS (Tandem) Spectra to NIST26 Search