Reversed Phase Solid Phase Extraction (SPE)
An end-capped C8 sorbent that offers moderate hydrophobic retention with negligible secondary polar interactions from active silanol groups. Ideal for compounds that may interact too strongly with a C18 sorbent.
Phenomenex: Strata C8
- Surface Area (m²/g): -
- Separation Mode: Reversed Phase
- Particle Size: 25, 55
- Recommended Use: Extraction of extremely hydrophobic compounds that are retained too tightly on C18-E.
Starting Method
Strata Reversed Phase
- Condition: 1 mL Methanol
- Equilibrate: 1 mL DI Water
- Load: Pretreated sample
- Wash: 1 mL 5% Methanol in DI Water, dry under vacuum for 2-5 min
- Elute: 1 mL Methanol
Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.
