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One Injection, Two Answers: Introducing Squad Metabolomics on Orbitrap Mass Spectrometers
SQUAD metabolomics combines targeted quantitation and untargeted discovery in a single Orbitrap MS experiment, delivering confident quantitative results alongside broad metabolite profiling.
Electrospray 101: What to Know About LC-MS Sources – and a First Look at Optispray
Discover how ion sources shape LC-MS performance and why electrospray transformed modern mass spectrometry. Explore EASY-Spray™, NanoSpray Flex™, and the new OptiSpray™ technology.
Exploring a Versatile LC–HRMS Strategy for NDSRI Determination in Beta Blocker Drug Substances
A single LC-HRMS method for NDSRI quantitation across six beta blockers. Discover how Orbitrap MS enables sensitive, robust analysis of trace nitrosamine impurities.
Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS
How can mAb manufacturing monitoring be simplified? Switchable 2D-LC-UV-MS workflows enable near real-time tracking of critical quality attributes and faster process decisions.
Sharper, Faster, Smarter: HRAM Orbitrap Mass Spectrometry Meets Postmortem Toxicology
HRAM Orbitrap LC-MS accelerates postmortem toxicology, enables retrospective screening for emerging drugs, and improves confidence in complex sample analysis.
From the Road to the Field: Decoding Chemical Transformation in Aging Tire and Artificial Turf Crumb Rubber
This study investigates chemical aging of tire and turf crumb rubber, identifying hundreds of transformation products and potential aging markers.
Upgrade Smarter: Trade In Your Current LC-MS System and Boost Lab Performance Without Breaking Budget
Upgrade your LC-MS with Thermo Fisher Scientific’s Trade-In / Trade-Up Program. Reduce costs, boost performance, and transition seamlessly to advanced mass spectrometry solutions.
News from LabRulezLCMS Library - Week 14, 2026
This week we bring you application notes by Agilent Technologies, KNAUER, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!
From Complexity to Clarity: Smarter PFAS Identification Workflows in Compound Discoverer Software
Non-targeted PFAS analysis using Orbitrap HRAM and Compound Discoverer 3.5 enables confident identification of thousands of PFAS through advanced libraries, scoring tools and visualization workflows.
Identification of Substructures in Unknowns Through MSn Data
How MSⁿ spectral libraries like mzCloud help identify substructures in unknown compounds. Learn how fragmentation data can guide structure elucidation and support identification of complex molecules.
