News from LabRulezLCMS Library - Week 40, 2026
LCMSArticle | Application

News from LabRulezLCMS Library - Week 40, 2026

This week we bring you technical note by KNAUER, application note by Shimadzu and posters by Thermo Fisher Scientific / HPLC Symposium and Waters Corporation / AOAC!
News from LabRulezLCMS Library - Week 40, 2026
News from LabRulezLCMS Library - Week 39, 2026
LCMSArticle | Application

News from LabRulezLCMS Library - Week 39, 2026

This week we bring you application notes by KNAUER and Shimadzu, technical note by Thermo Fisher Scientific and poster by Waters Corporation / SOFT!
News from LabRulezLCMS Library - Week 39, 2026
Comprehensive investigation of matrix effect evaluation approaches for reliable quantification in bioanalysis using UHPLC-MS/MS
LCMSScientific article | Science and research

Comprehensive investigation of matrix effect evaluation approaches for reliable quantification in bioanalysis using UHPLC-MS/MS

A systematic UHPLC-MS/MS study shows that matrix-effect estimates based only on calibration slopes can be biased and introduces an intercept-based correction.
Comprehensive investigation of matrix effect evaluation approaches for reliable quantification in bioanalysis using UHPLC-MS/MS
Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry
LCMSScientific article | Science and research

Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry

This study introduces an HDX-MS titration workflow for quantifying protein–ligand affinities at global, peptide, and residue resolution.
Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry
News from LabRulezLCMS Library - Week 28, 2026
LCMSArticle | Poster

News from LabRulezLCMS Library - Week 28, 2026

This week we bring you application notes by Agilent Technologies and Metrohm and posters by Shimadzu/ASMS, Thermo Fisher Scientific/ASMS and Waters Corporation/ASMS!
News from LabRulezLCMS Library - Week 28, 2026
News from LabRulezLCMS Library - Week 27, 2026
LCMSArticle | Application

News from LabRulezLCMS Library - Week 27, 2026

This week we bring you application notes by Agilent Technologies and Metrohm and posters by Shimadzu/ASMS, Thermo Fisher Scientific/ASMS and Waters Corporation/ASMS!
News from LabRulezLCMS Library - Week 27, 2026
News from LabRulezLCMS Library - Week 24, 2026
LCMSArticle | Application

News from LabRulezLCMS Library - Week 24, 2026

This week we bring you application notes by Agilent Technologies, KNAUER and Shimadzu, other document by Thermo Fisher Scientific and poster by Waters Corporation/ASMS!
News from LabRulezLCMS Library - Week 24, 2026
A Novel Compact Multi-Reflecting Time-of-Flight Mass Spectrometer
LCMSScientific article | Science and research

A Novel Compact Multi-Reflecting Time-of-Flight Mass Spectrometer

This study introduces a compact multi-reflecting TOF mass spectrometer combining high resolution, fast acquisition, and broad dynamic range for LC-MS/MS.
A Novel Compact Multi-Reflecting Time-of-Flight Mass Spectrometer
News from LabRulezLCMS Library - Week 19, 2026
LCMSArticle | Application

News from LabRulezLCMS Library - Week 19, 2026

This week we bring you application notes by Agilent Technologies, Metrohm and Thermo Fisher Scientific, technical note by Shimadzu and poster by Waters Corporation / AAPS!
News from LabRulezLCMS Library - Week 19, 2026
LCMS-Net: Deep Learning for Raw High Resolution Mass Spectrometry Data Applied to Forensic Cause-of-Death Screening
LCMSScientific article | Science and research

LCMS-Net: Deep Learning for Raw High Resolution Mass Spectrometry Data Applied to Forensic Cause-of-Death Screening

LCMS-Net is an end-to-end deep learning model for raw LC-HRMS data, improving accuracy, reducing preprocessing, and minimizing batch effects in metabolomics.
LCMS-Net: Deep Learning for Raw High Resolution Mass Spectrometry Data Applied to Forensic Cause-of-Death Screening