What if you could assess a tumor's metastatic potential — without extensive sample prep — directly from tissue? Rachel Wood is working on exactly that.Rachel Wood is a PhD candidate at Queen's University (Kingston, Ontario),&nbsp;working jointly in the labs of Dr. Richard Oleschuk (Chemistry) and Dr. Chris&nbsp;Nicoll (Pathology &amp; Molecular Medicine). Her research applies Ambient Ionization Mass Spectrometry — specifically the Liquid Microjunction Surface Sampling Probe &nbsp;(LMJ-SSP) and Desorption Electrospray Ionization (DESI) — to profile the metabolomics of non-metastatic and metastatic clear cell Renal Cell Carcinoma (ccRCC) cell lines. The long-term goal: a rapid, minimally invasive MS-based prognostic tool for kidney cancer.This is the first reported use of LMJ-SSP to assess metastatic status in ccRCC —&nbsp;and early PCA results are already showing distinct separation between cell line&nbsp; profiles.<h5>In this episode, David and Rachel cover:</h5><ul><li>Why ccRCC is such a resistant biomarker problem despite active genomic, proteomic, and metabolomic research</li><li>The clinical stakes of "diagnosed by accident" — and what a prognostic biomarker actually needs to do for a clinician</li><li>How AIMS complements (not replaces) LC-MS in a discovery-phase cancer workflow</li><li>LMJ-SSP vs. DESI: what each technique sees that the other misses, including spatial resolution differences (~1mm vs. ~50µm)</li><li>Why Rachel runs LMJ-SSP on both a triple quad and a Q-TOF — and what each instrument contributes to the same research question</li><li>How her lab repurposed a 3D printer as a custom automated XYZ sampling stage with 50µm movement precision</li><li>Managing high-dimensional metabolomics data across two polarities, two cell lines, and two mass analyzers — the pipeline explained</li><li>What unsupervised machine learning (PCA) showed in early results</li><li>The path from cell lines to excised tumor tissue to, ultimately, liquid biopsies</li><li>Advice for analytical chemists considering work at the chemistry–oncology interface</li></ul><h3>Video Transcription</h3>Kidney cancer remains a difficult biomarker problem, particularly when researchers try to distinguish tumors that are likely to behave aggressively from those that are not. In a recent episode of Concentrating on Chromatography, PhD researcher Rachel Wood discussed how she is combining rapid ambient ionization mass spectrometry, LMJ-SSP, DESI, multivariate data analysis, and conventional LC-MS workflows to investigate the molecular differences associated with clear cell renal cell carcinoma and its metastatic potential.<h4>Returning to the research question that started it all</h4>Wood first encountered kidney cancer research during her undergraduate studies. Although she later moved into a more instrumentation-focused master’s project involving breast cancer, the subject of kidney cancer remained unfinished business.When the opportunity arose to choose a PhD project, she returned to the field that had originally sparked her interest in research. She is now conducting her doctoral work at Queen’s University in Kingston, Ontario, in an interdisciplinary environment spanning chemistry, pathology, molecular medicine, computer science, and clinical research.<h4>Why clear cell renal cell carcinoma is such a difficult biomarker problem</h4>Wood’s research focuses on clear cell renal cell carcinoma (ccRCC), which represents the majority of kidney cancer cases discussed in the interview.The difficulty is not a lack of research effort. Genomics, proteomics, and metabolomics studies have all produced promising biomarker candidates. The challenge is that different studies often identify different sets of markers, with relatively little overlap between them.Patient-to-patient biological variability further complicates the picture. A candidate biomarker panel that performs well in one cohort may not reproduce equally well in another. Selecting which features deserve further investigation therefore becomes a major analytical and biological challenge.<h4>From incidental diagnosis to prognostic information</h4>Another difficulty is the way kidney cancer is often discovered.Rather than being detected through a dedicated screening program, tumors may be found incidentally during imaging performed for another reason. According to Wood, the ideal solution would be a diagnostic biomarker capable of detecting kidney cancer early. Such a marker is not currently available within the scope of the work she described.That places additional importance on prognostic biomarkers. Once a tumor has been detected, clinicians need as much information as possible about how aggressive it may be and how likely it is to progress.Wood’s current work is therefore not attempting to declare directly that a particular patient has metastatic disease. Instead, the goal is to understand what changes biologically as a tumor moves from a less aggressive to a more aggressive state.That means asking which molecular pathways change, which mechanisms become altered, and which analytes may eventually provide useful indicators of tumor behavior.<h4>AIMS and LC-MS answer different questions</h4>A central theme of the interview was the relationship between rapid ambient ionization mass spectrometry and conventional LC-MS.Wood is clear that AIMS is not intended to replace LC-MS. Instead, she sees the two approaches as complementary.AIMS provides a rapid way to obtain a broad molecular overview of a sample with minimal preparation. This makes it especially useful during the discovery phase, when the goal is to gather as much molecular information as possible and identify features that distinguish biological groups.LC-MS then becomes valuable when those features need to be separated, characterized more carefully, and quantified with greater confidence.In Wood’s workflow, rapid MS screening can therefore help identify which analytes deserve closer attention before more targeted LC-MS investigations are performed.<h4>What “minimal sample preparation” actually means</h4>The amount of sample preparation required depends strongly on the type of material being analyzed.Wood currently works mainly with cultured human cell lines, which means much of the preparation begins with growing the cells themselves. Depending on the experiment, the cells may then be chemically lysed or subjected to fixation, paraffin embedding, and sectioning before analysis by LMJ-SSP or DESI.She also notes that the possibilities would be different for freshly excised tumor material. In an appropriate perioperative or biosafety laboratory setting, LMJ-SSP could potentially be used to analyze tumor margins more directly.The practical meaning of “minimal preparation” is therefore highly dependent on the sample and the analytical question being asked.<h4>Why combine LMJ-SSP and DESI?</h4>Rather than choosing between LMJ-SSP and DESI, Wood uses the two approaches because they provide different types of information.LMJ-SSP offers rapid, localized analysis and can accommodate samples with uneven surface topography, which is particularly useful for excised tissue.DESI, by contrast, provides substantially higher spatial resolution. In the workflow described in the interview, DESI can achieve spatial resolution on the order of tens of micrometers, whereas LMJ-SSP operates at a much larger sampling scale depending on probe design.That higher spatial resolution is important when moving from simplified cell-line models toward actual tumor tissue, where the molecular organization of different regions may reveal biologically relevant differences.Combining both techniques therefore enables researchers to balance speed, surface compatibility, and spatial information.<h4>Two mass analyzers for two parts of the same problem</h4>Wood also uses two different mass spectrometers in her LMJ-SSP work.Most of the discovery work is carried out using a triple quadrupole mass spectrometer, particularly because her project focuses strongly on lower-mass analytes and small molecules.Once statistically important analytes have been identified, a Q-TOF instrument can be used for MS/MS experiments and tentative structural identification.The two instruments therefore address different stages of the workflow: one supports broad discovery and comparison, while the other provides additional structural information needed to connect selected features with possible metabolic pathways.<h4>Turning a 3D printer into an automated sampling platform</h4>One of the most unusual elements of the project is the automated sampling system used with LMJ-SSP.Historically, LMJ-SSP measurements could be performed manually or with custom-built XYZ positioning stages. Wood’s laboratory instead adapted a 3D printer into an automated positioning system.Custom software controls the printer and moves the sampling probe with precise control over its X, Y, and Z positions. According to Wood, the system enables movements down to approximately 50 µm and also controls parameters such as the contact time between the probe and sample and the delay between consecutive sampling events.This level of automation improves reproducibility because variables that would otherwise depend on manual operation can be controlled systematically.Even the Z-position can be programmed, allowing the probe to operate at constant or varying heights depending on the sample surface.<h4>Managing high-dimensional MS data</h4>The experimental design creates a large data-analysis challenge.Wood is working with multiple cell lines, both ionization polarities, and more than one mass analyzer. To maintain traceability, she analyzes the data in clearly defined subsets.A typical workflow might begin with one mass analyzer and one polarity. Within that condition, the lower-aggressiveness and higher-aggressiveness cell models can then be compared directly.The data processing pipeline includes steps such as:<ul><li>binning,</li><li>normalization,</li><li>transformation,</li><li>dimensionality reduction,</li><li>identification of discriminating molecular features.</li></ul>Once relevant features are identified, MS/MS analysis can be used to investigate them further. The same process is then repeated across other polarities and instruments.<h4>Unsupervised machine learning reveals distinct molecular profiles</h4>Machine learning is particularly valuable because the AIMS datasets are highly dimensional, containing very large numbers of molecular features across multiple samples.Wood’s initial analysis has included principal component analysis (PCA), an unsupervised dimensionality-reduction technique.The early results are encouraging: the non-metastatic and metastatic cell-line models separate clearly in PCA space.That does not itself identify a definitive biomarker panel, but it indicates that the two biological states have distinguishable molecular profiles even though both belong to the same kidney cancer subtype.This provides an important foundation for identifying which specific metabolites or molecular pathways may be responsible for the separation.<h4>Testing LMJ-SSP for metastatic status</h4>A particularly novel aspect of Wood’s project is the use of LMJ-SSP to investigate differences associated with metastatic status.She had previously worked on distinguishing healthy and cancerous tissues, where the biological differences are relatively large. Comparing two states within the same cancer type is more demanding because the molecular changes may be much subtler.The scientific motivation, however, is strong. Tumors discovered at later stages carry greater concern for metastatic progression, making it important to understand the molecular changes associated with increasingly aggressive behavior.For Wood, this made the methodological risk worthwhile: the analytical challenge directly addresses an area where better prognostic information could ultimately have clinical value.<h4>A long-term goal: rapid MS-based prognostic testing</h4>The long-term vision extends beyond cell-line research.Wood is interested in whether rapid, minimally invasive mass spectrometry could eventually contribute to clinical decision-making.One possibility would be identifying a diagnostic biomarker in a liquid biopsy, potentially using blood or urine. A urine-based marker capable of contributing to earlier detection would be particularly attractive for kidney cancer.For prognostic applications, the goal would be slightly different. Once a tumor is discovered, molecular information could help characterize its likely behavior and provide clinicians with additional evidence when deciding between immediate treatment, surgery, or other management strategies.Wood emphasizes that such a tool would not replace standard clinical workflows. Instead, it would provide additional molecular information to complement existing diagnostic and pathological approaches.<h4>Why interdisciplinary work matters</h4>Throughout the interview, Wood repeatedly returns to the importance of collaboration.Her research sits at the intersection of analytical chemistry, pathology, oncology, computation, and clinical medicine. No single researcher can remain equally current in all of these fields.Working closely with pathologists, computer scientists, surgeons, medical students, and other specialists therefore provides both scientific expertise and a way to stay connected with developments outside one’s immediate discipline.For Wood, the biological context has also changed how she thinks about analytical chemistry. Developing a new instrument or method is important, but understanding who may ultimately benefit from that analytical capability makes the research more meaningful.That patient-centered perspective is now an integral part of how she approaches the project.<h4>An intersection full of opportunities</h4>Wood describes the interface between analytical chemistry and oncology as an especially exciting area for young researchers.The work can range from troubleshooting instrumentation to interpreting pathology, developing statistical methods, and collaborating across disciplines. That diversity creates constant opportunities to learn and to apply analytical chemistry to clinically relevant questions.Her project illustrates that modern mass spectrometry research is increasingly about more than generating spectra. It involves connecting instrumentation, spatial sampling, multivariate statistics, machine learning, biological interpretation, and clinical needs into a single analytical strategy.And in kidney cancer, where reliable prognostic biomarkers remain difficult to establish, that integrated approach may be particularly valuable.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

AIMS vs. LC-MS for Cancer Diagnostics: ccRCC Metabolomics with Rachel Wood

In the week of September 21, the following webinars await you in the field of liquid phase and especially HPLC and LC/MS.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a></h4>👉 Search and filter in the largest global database with over 6 000 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1. Waters Corporation: Strengthening SPE Workflows for Today’s Laboratory</h5><ul><li>Mo, 21.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6514">Registration</a></li></ul>Learn how to optimize SPE workflows with best practices for sorbent selection, recovery troubleshooting, and reducing matrix effects in modern analytical laboratories.<h5>2. Agilent Technologies: From Crude to Candidate: Scaling Preparative Chromatography with Confidence</h5><ul><li>Mo, 21.9.2026 18:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6498">Registration</a></li></ul>Learn how to scale preparative chromatography from crude sample to purified candidate, with practical strategies for method development, fraction collection, and method transfer.<h5>3. SCIEX: Extending the power of LC MS/MS: advanced workflows with QTRAP®</h5><ul><li>Tu, 22.9.2026 14:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6518">Registration</a></li></ul>Discover how MRM³ and QTRAP workflows provide greater selectivity and lower limits of quantification for LC-MS/MS analysis in complex matrices.<h5>4. Technology Networks: Improving Efficiency in Routine PFAS Analysis Using EPA Methods 533 and 1633A</h5><ul><li>Tu, 22.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6517">Registration</a></li></ul>Explore how automated QC monitoring and the SCIEX novus V55 system support high-throughput PFAS quantitation using EPA Methods 533 and 1633A.<h5>5. Phenomenex: Expanding the Evidence: New Data for More Reliable PFAS Analysis</h5><ul><li>We, 23.9.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6522">Registration</a></li></ul>Discover how new analytical data and contamination control strategies can improve baseline performance, sensitivity, and reliability in PFAS analysis.<h5>6. SCIEX: How is capillary electrophoresis being used to analyze DNA and RNA</h5><ul><li>We, 23.9.2026 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6521">Registration</a></li></ul>Explore how capillary electrophoresis supports DNA and RNA analysis, from plasmid quality assessment to mRNA impurity profiling, viral vector characterization, and oligonucleotide workflows.<h5>7. Thermo Fisher Scientific: A novel monodisperse supermacroporous reversed-phase platform for comprehensive nucleic acid analysis across a broad size range</h5><ul><li>We, 23.9.2026 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6476">Registration</a></li></ul>Discover how a novel monodisperse supermacroporous reversed-phase platform enables comprehensive nucleic acid analysis across a broad size range, from short oligonucleotides to mRNA.<h5>8. Waters Corporation: The Next Frontier in Nitrosamines Testing: Detection and Risk Assessment in Packaging and IV Infusion Bags</h5><ul><li>We, 23.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6520">Registration</a></li></ul>Learn how LC-MS/MS supports nitrosamine detection and risk assessment in packaging materials while addressing extractables and leachables challenges in IV infusion bags.<h5>9. MDPI: Membrane Technologies for Water and Food Sustainability</h5><ul><li>We, 23.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6561">Registration</a></li></ul>Explore membrane technologies for water and food sustainability, international research collaboration, and opportunities within the CYTED Program.<h5>10. Agilent Technologies: Unlocking Lab Productivity: Automation Opportunities for LC/MS Laboratories</h5><ul><li>We, 23.9.2026 18:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6495">Registration</a></li></ul>Discover how automation can increase productivity in LC/MS laboratories by reducing manual tasks, improving workflow efficiency, and supporting scalable analytical operations.<h5>11. Thermo Fisher Scientific: Comparison of biocompatible and inert UHPLC systems for LC-UV quantitation of large RNA</h5><ul><li>Th, 24.9.2026 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6477">Registration</a></li></ul>Learn how the Vanquish Amplify system minimizes metal interactions during LC-UV analysis of large RNA and explore the performance of biocompatible and inert UHPLC systems.<h5>12. Agilent Technologies: Next-Generation Pathogen Genomics: The Long-Read Advantage</h5><ul><li>Th, 24.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6526">Registration</a></li></ul>Explore long-read sequencing and automated target enrichment in pathogen genomics and learn how Agilent SureSelect and Magnis NGS support improved pathogen detection.<h5>13. Evosep Biosystems: Advancing Plasma Proteomics</h5><ul><li>Th, 24.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6523">Registration</a></li></ul>Discover advances in plasma proteomics and learn how high-throughput analytical workflows can accelerate biomarker discovery and cancer research.<h5>14. Waters Corporation: Applications of Multi-Angle Light Scattering for Biotherapeutic Characterization</h5><ul><li>Th, 24.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6430">Registration</a></li></ul>Learn how multi-angle light scattering (MALS) supports confident characterization of monoclonal antibodies, antibody-drug conjugates, and AAV viral vectors.

Webinars LabRulezLCMS Week 39/2026

Forced degradation analysis of recombinant adeno-associated virus serotype 8 based on analytical anion exchange chromatography coupled to orthogonal characterization

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Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

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Watrex LSS-205 Liquid Sensing System

Liquid Sensing System LSS-205 is a universal sensing system for monitoring the level of your chromatographic system liquids.

Universal sensing system for monitoring the level of your chromatographic system liquids. The daily task in the chromatographic laboratory is the manipulation of mobil phases. The operator must check the supply of solvents at the inlet of the device and regular monitor the condition of the waste solvent container. The LSS-205 greatly simplifies these tasks.<blockquote>Price: 578<bdi>&nbsp;€ ex VAT</bdi></blockquote>LSS-205 is a universal accessory for any (chromatographic) system. The level sensors used in the LSS-205 system are contactless, do not require immersion in liquid, and are installed on the outer shell of a non-metallic solvent container. The method of mounting the sensor allows placement on a container of virtually any shape and size.The LSS-205 central unit is ready to process the signal from up to five liquid sensors, which can be individually set to trigger an alarm in the event of a missing or present liquid. The error status of the individual sensors is indicated optically directly on the central unit and the alarm can be accompanied by an acoustic signal. An external loud siren suitable for a noisy environment is available as an option to the central unit.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_LSS_205_Liquid_Sensing_System_33_0fd5d29a02/Watrex-LSS-205-Liquid-Sensing-System-33.jpg" alt="Watrex LSS-205 Liquid Sensing System"><h3>FEATURES</h3><ul><li>Simple operation</li><li>Flexible in application</li><li>Multiple connection option</li><li>Starter kit contents: central unit, one sensor, light bar, power supply</li><li>Color touch panel control</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Power supply: 5V DC (wall mount power supply or USB port of PC)</li><li>Number of liquid sensors: 1 – 5</li><li>Alarm condition: individually adjustable for each sensor (off, missing liquid, liquid present)</li><li>Internal alarm indication: high intensity LED for each sensor</li><li>Internal acoustic alarm: 80dB, common for all sensors</li><li>External optical signaling: connector on the central unit</li><li>External acoustic alarm: optional 105 dB external horn</li><li>Alarm signal for external devices: logic (open collector), relay switching contact</li><li>Computer connection: micro USB connector, simple text communication protocol</li><li>Firmware update: possible in field</li><li>Dimension: 130x80x30 mm</li><li>Weight: 250 g</li><li>Sensor dimensions: 50x30x15 mm</li><li>Sensor connection cable: 2 m length</li><li>Sensor mounting: plastic holder with flexible silicon tube (length 700 mm, other lengths on request)</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_LSS_205_Liquid_Sensing_System_6_7b35aadbb7/Watrex-LSS-205-Liquid-Sensing-System-6.jpg" alt="Watrex LSS-205 Liquid Sensing System - level sensor"><h3>Ordering information:</h3><h5>PN/Component:</h5><ul><li>40-0728 Starter Kit (incl. 1 sensor + light)</li><li>40-0738 LSS-205 Additional Sensor</li><li>40-0841 LSS-205 Additional 2 Sensors</li><li>40-0842 LSS-205 Additional 3 Sensors</li><li>40-0843 LSS-205 Additional 4 Sensors</li><li>40-0838 LSS-205 External Alarm Horn</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/dedicated-instruments/lss-205-starter-kit/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex P102 HPLC pump, Stainless Steel

Watrex P102 high performance liquid chromatography (HPLC) pump is designed to be a reliable component within a basic analytical or sophisticated research instruments.

Watrex P102 high performance liquid chromatography (HPLC) pump is designed to be a reliable component within a basic analytical or sophisticated research instruments.<blockquote>Price: 4 556<bdi>&nbsp;€ ex VAT</bdi></blockquote>While ideal for HPLC applications, the Model P102 pump is also useful as a metering pump for general laboratory or industrial use. The pump features dual self flushing pump heads with overlapping cams for reduced pulsation.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Delta_Chrom_P102_pump_red_a35f480572.jpg" alt="Watrex: P102 HPLC pump, Stainless Steel" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_Delta_Chrom_P102_pump_red_a35f480572.jpg 208w," sizes="100vw" width="1020" height="765"><h3>KEY FEATURES</h3>Double Piston Design: The double piston design ensures exceptional accuracy and precision in the delivery of solvents, making it ideal for applications that demand the utmost reliability.Wide range of operating conditions: With a wide range of flow rates, from the minutest quantities to larger volumes, our HPLC pump adapts to your diverse experimental needs without compromising precision. Handle high-pressure applications with confidence. Our pump delivers a maximum pressure of&nbsp;35 MPa, ensuring efficiency and reliability in even the most challenging chromatographic separations.Stainless Steel or PEEK Versions: Choose the material that suits your needs. Opt for the durability of stainless steel or the biocompatible advantages of PEEK. Both versions maintain high chemical resistance, making them suitable for a diverse range of chromatographic solvents.Efficient Pulse Dampener: Our integrated pulse dampener minimizes pressure fluctuations, ensuring a smooth and controlled flow. Experience enhanced separation quality and purity, thanks to the efficient dampening of pulsations.Versatile Applications: Whether you’re conducting routine analytical experiments or pushing the boundaries of chromatographic research, our pump caters to a wide array of applications, ensuring versatility in your lab.Demanding Dosing Applications: Excel in applications that demand precise and stable dosing. Achieve a stable jet stream for your research experiments, ensuring accuracy and reliability in every sampling.High-Quality Construction: Crafted with durability in mind, our pump is built to withstand the rigors of daily laboratory use. The robust construction ensures longevity and reliability.Chemical Compatibility: The pump is designed to handle a variety of solvents with ease, providing excellent chemical compatibility. This feature is crucial for researchers working with diverse samples and experimental conditions.Intuitive Controls: The user-friendly interface simplifies pump operation, allowing for easy programming and monitoring. Spend less time on instrument setup and more time focusing on your research.Applications: Whether you’re in pharmaceuticals, biotechnology, environmental analysis, or academic research, our HPLC pump is the go-to solution for achieving unparalleled precision in liquid chromatography.Conclusion: Elevate your chromatography experiments with our HPLC pump—where precision meets reliability. Experience the future of liquid chromatography and unlock new possibilities in your laboratory. Contact us today to discover how our HPLC pump can transform your research endeavors.<h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0,01 ml/min – 9,99 ml/min with step 0.01 ml/min (analytical)</li><li>Pressure: 42 Mpa/6000 psi (analytical, PEEK)</li><li>Flow precision: ± 0,2% RSD @ 1mL/min. and 7 MPa psi&nbsp;</li><li>Flow accuracy: ± 1% @ 1mL/min. and 7 MPa psi (analytical)</li><li>Pressure accuracy: ± 2% of full-scale, with 80:20 H2O/IPA @ 7 MPa</li><li>Pulsation: better than ± 0.5% @ 1mL/min. and 7 MPa&nbsp;</li><li>Remote control: USB</li><li>Remote control: Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/isocratic-pumps/p102-hplc-pump-dual-head-stainless-steel/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Waters Arc Premier LC System

The Arc Premier System features new, innovative MaxPeak High Performance Surfaces (HPS) Technology, which effectively reduces non-specific adsorption due to metal interactions, without complicated mobile phases or laborious methods.

<div><div><h4>See clearly and consistently, with confidence.</h4></div></div><div><div>Today’s scientists and lab managers need to confidently produce the most accurate, reliable, and reproducible data. The Arc Premier System produces correct, robust results from the very first injection, reliably and easily.&nbsp;The Arc Premier System features the new, innovative solution of MaxPeak High Performance Surfaces (HPS) Technology, which effectively reduces non-specific adsorption due to metal interaction — without complicated mobile phases or laborious methods. The Arc Premier System sharpens chromatographic peaks for metal-sensitive compounds by eliminating secondary interactions from metals, resulting in:<ul><li>Improved compliance from higher quality data</li><li>Faster, more reproducible, and accurate data integration</li><li>Shorter time from sample to result, without conditioning</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_6d7c95a93a.jpg" alt="Waters Arc Premier LC System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_6d7c95a93a.jpg 245w," sizes="100vw" width="1024" height="611">With the Arc Premier System, we continue to deliver on the product quality you expect, combined with recent innovations in MaxPeak HPS Technology, to always deliver the best possible results.&nbsp;Whether you are working to ensure the safety of a new and innovative product, maintain the consistency and supply of a current one, or test your food safety and quality, the Arc Premier System gives you greater data quality, flexibility, reproducibility, and faster data integration with right first-time results right out of the box, without the need for complicated mobile phases and laborious methods to prepare your system.<div><div><div><div><div><div><ul><li>MaxPeak HPS Technology, minimizing risk of metal-analyte interactions</li><li>Pressure envelope extends to 9500 psi through a flow rate range of 1–5 mL/min, providing an optimized pairing with column dimension and particle size</li><li>Flexible quaternary and binary pumping options</li><li>High performance analytical optical detectors, include photodiode array (PDA), UV/Vis, and fluorescence (FLR)</li><li>Mass detection options with the ACQUITY™ QDa™ Mass Detector,<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1543"> SQD2 Detector</a>, <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/209">Xevo™ TQ-S micro</a>, and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/212">Xevo TQ-S cronos</a></li><li>Flexible column manager options available for up to six columns ranging in length from 50 mm to 300 mm, with a temperature range of 4 °C to 90 °C</li><li>Auto•Blend Plus™ Technology for mobile phase reproducibility and Gradient SmartStart for method transfer</li><li>Wide range of trusted particle technologies in MaxPeak Premier Columns</li><li>Compliance-ready <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/627">Empower™ Chromatography Data System </a>(CDS) delivering high quality data integrity</li><li>Automated quantification tools to minimize compliance costs and time</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_2_d1a922ae6d.jpg" alt="Waters Arc Premier LC System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_2_d1a922ae6d.jpg 245w," sizes="100vw" width="1024" height="585"></div></div><div><div><h3>Flexible and Robust HPLC Designed for Your Development and Routine Testing Needs</h3><ul><li>Low dispersion HPLC: High performing HPLC with bandspread of &lt;30 μL for high chromatographic resolution.&nbsp;</li><li>Versatile column management: Support for analytical LC column dimensions up to 300* mm with capacity to automatically select between as many as six analytical columns. Equipped with independently controlled temperature zone, active pre-heating, and eCord™ Intelligent Chip Technology for Waters columns.* MaxPeak Premier Columns are recommended for use with the Arc Premier System and are currently only available in lengths up to 150 mm.</li><li>Flow-through needle Injector: Volume range of 0.1 to 1000 μL and ultra-low carryover performance compatible with sensitive LC-MS applications.</li><li>High Performance Surfaces Technology: With MaxPeak HPS Technology, analytes are impeded from Lewis acid-base interactions and adsorptive losses. This technology has proven to be effective in improving the analysis of electron-rich compounds, such as those containing phosphate and carboxylate groups.</li><li>Consumables: Compatible with MaxPeak Premier Column chemistry to meet the needs of your reversed-phase and HILIC applications. Quality Control (QC) Reference Material benchmarks your Arc Premier System and enables perfect resolution. Certified clean <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/197">QuanRecovery™ vials</a> to give full sample integrity.</li><li>High performance analytical detectors : A wide range of high-performance detection capabilities, optimized with HPS, to support diverse applications. Includes photodiode array, UV/Vis, and fluorescence, with the additional option of single and triple quad mass detection.</li><li>Solvent blending: Quaternary or binary solvent mixing. Delivers precise and accurate separations at pressures up to 9500 psi. Optional solvent select valve adds access to additional solvents. Automated solvent compressibility, integrated solvent degassing, and programmable seal wash maximize flow accuracy, precision, and reliability.</li><li>Auto•Blend Plus Technology: Reduce human error and accelerate method robustness testing for chromatographic methods by programming gradients to control mobile phase pH and ionic strength.</li><li>Gradient SmartStart: Adjust the injection relative to the gradient start to emulate other HPLC systems’ dwell volumes, without the need to alter the gradient table. Successfully transfer most methods in just two injections.</li><li>Laboratory Informatics: Software control within your existing Empower or MassLynx™ infrastructure. Empower Method Validation Manager (MVM) allows you to perform chromatographic method validation in one application. Optional S-Matrix Fusion Software automates your method development according to AQbD guidelines.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_3_5db411b90a.jpg" alt="Waters Arc Premier LC System" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_3_5db411b90a.jpg 234w," sizes="100vw" width="1024" height="682"></div></div></div></div><div><div><div><div><div><div><h3>The Universal Platform for Liquid Chromatography</h3>Non-specific adsorption of metal-sensitive compounds is an unpredictable challenge, resulting in chromatography with large relative standard deviations (RSDs) and broad, overlapping peaks, which can be challenging to integrate quickly and be accurate consistently.Designed with MaxPeak HPS Technology and paired with MaxPeak Premier 2.5 μm Columns, the Arc Premier System improves data quality for challenging compounds, including metal-sensitive compounds tested with LC methods – so you can see clearly and consistently, with confidence.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_8_a4038daa52.jpg" alt="Waters Arc Premier LC System: Figure 1. Analysis of adenosine monophosphate, adenosine diphosphate, and adenosine triphosphate. Significant improvements to sensitivity and recovery are observed with the Arc Premier Solution compared to a conventional LC system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_8_a4038daa52.jpg 245w," sizes="100vw" width="1123" height="520"></div></div></div></div></div></div></div></div><div><div><h3>Clear</h3>Future-proof your lab for the next generation of challenging compounds with MaxPeak HPS Technology, which sharpenspeaks for metal-sensitive compounds, resulting in higher data quality and improved sensitivity with chromatographic reproducibility and precision.Data quality and performance are critical for your lab, but those can’t come at the sacrifice of ruggedness and ease of use.&nbsp;With MaxPeak HPS Technology and flexible LC performance, your lab gets the typical benefits of an LC system optimized for 2.x μm column chemistry with the MaxPeak HPS Technology’s ability to shorten run times and achieve sharp peaks - no lengthy and complex conditioning and conditioning methodologies for metal-sensitive compounds required.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_9_34ec4befec.jpg" alt="Waters Arc Premier LC System: Figure 2. Analysis of adenosine triphosphate. Lower limits of detection and increased calibration curve linearity are demonstrated with the Arc Premier Solution compared to a conventional LC system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_9_34ec4befec.jpg 245w," sizes="100vw" width="940" height="523"></div></div><div><div><h3>Consistent</h3>Seeing your results more clearly than ever is critical, but those results must be consistent and error-free and your methods easily reproducible, so you can spend less time on analysis and ensure compliance.&nbsp;By significantly sharpening peak shapes for metal-sensitive analytes, scientists report an improvement in %RSD when integrating data from metal-sensitive compounds on the Arc Premier System. Along with the improvement in data consistency users also report a decrease of time needed to integrate peaks by approximately 30%.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_f80500f8a4.jpg" alt="Waters Arc Premier LC System: Figure 3. Analysis of hydrocortisone phosphate, betamethasone phosphate, dexamethasone, and dexamethasone acetate. Peak heights increased and peak shapes are more symmetrical for metal- sensitive compounds on the Arc Premier Solution compared to a conventional LC system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_f80500f8a4.jpg 235w," sizes="100vw" width="1381" height="918">The Arc Premier System eliminates the need for variability-prone conditioning and complex mobile phases – so you can minimize user errors, improve compliance, and reduce expensive audits from red flag-inducing conditioning injections.Your organization needs to reliably migrate higher-quality methods between your systems for maximum reproducibility. With MaxPeak HPS Technology and flexible pump configurations, your lab can easily, reliably migrate methods between MaxPeak HPS-based systems quickly, saving you time and money from unnecessary rework. You can also migrate methods from non-MaxPeak HPS-enabled systems safely, as method performance of non-metal-sensitive compounds have been shown to not be adversely affected.Combining higher data quality with ease of use for your analysts and seamless method transfer, enables results that can be generated consistently between runs and with various analysts.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_6_5332aab31f.jpg" alt="Waters Arc Premier LC System: Figure 4. Analysis of hydrocortisone phosphate, betamethasone phosphate, dexamethasone, and dexamethasone acetate. A zoom in on the baseline shows improved peak shapes and resolution for metal-sensitive compounds on the Arc Premier Solution compared to a conventional LC system, improving baseline resolution." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_6_5332aab31f.jpg 229w," sizes="100vw" width="1380" height="942"><h3>Confident</h3>Reducing analytical uncertainty and achieving peace of mind are important for your organization. With MaxPeak HPS Technology, metal-sensitive analytes become visible that were previously undetectable. This allows you to quickly and confidently know that you’ve seen everything in your sample, giving you the confidence to stand behind your data-driven decisions.The combination of MaxPeak HPS Technology, flexible pump and column management options, and precise optical and MS detection give you the method development and verification capabilities to know that no matter the sample - you can deliver a robust method you can stand behind.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_2_85f2f7cc29.jpg" alt="Waters Arc Premier LC System: Figure 5. Analysis of data of hydrocortisone phosphate, betamethasone phosphate, dexamethasone, and dexamethasone acetate from an Arc Premier System and a conventional LC system by six users. Peak area reproducibility improved 9 – 124x when integrating the same data from metal-sensitive compounds across six users." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_2_85f2f7cc29.jpg 239w," sizes="100vw" width="1243" height="810"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_5_514749f32d.jpg" alt="Waters Arc Premier LC System: Figure 6. Analysis of acetaminophen, caffeine, leucine enkephalin, sulfadimethoxine, amitriptyline, reserpine, and terfenadine shows that non-metal-sensitive compounds demonstrate comparable performance between the Arc Premier Solution and conventional LC systems." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_5_514749f32d.jpg 245w," sizes="100vw" width="1242" height="735"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_7_edc8ecaa93.jpg" alt="Waters Arc Premier LC System: Figure 7. Comparison of adenosine triphosphate and adenosine diphosphate peaks using a conventional LC system and the Arc Premier Solution over 120 injections. The peak areas of metal-sensitive compounds remain constant from the first to the 120th injection using the Arc Premier Solution. Peak areas of metal-sensitive compounds on a conventional LC system continuously increase over time and do not stabilize even after 120 injections." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_7_edc8ecaa93.jpg 218w," sizes="100vw" width="1038" height="744"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_3_f1cca337bc.jpg" alt="Waters Arc Premier LC System: Figure 8. Comparison of adenosine triphosphate and adenosine diphosphate peaks using a conventional LC system and the Arc Premier Solution over 120 injections. The peak areas of metal-sensitive compounds remain constant from the first to the 120th injection using the Arc Premier Solution showing less than a 1% change in peak area for all compounds. Peak areas of metal-sensitive compounds on a conventional LC system show an increase of 2–35% when compared to the first injection and show no signs of stabilization." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_3_f1cca337bc.jpg 216w," sizes="100vw" width="1039" height="750"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Arc_Premier_LC_System_4_1dae3909ae.jpg" alt="Waters Arc Premier LC System: Figure 9. Adenosine triphosphate, adenosine diphosphate, adenosine monophosphate, and adenosine stability using the Arc Premier Solution over 1000 injections. The peak areas of metal-sensitive compounds remain consistent over 1000 injection using the Arc Premier Solution demonstrating the robustness of the system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Arc_Premier_LC_System_4_1dae3909ae.jpg 243w," sizes="100vw" width="1040" height="669"></div></div></div></div>

Watrex Streamline FC1 Fraction Collector

The fully automated fraction collector FC1 offers a universal solution for a number of applications requiring the collection of fractions, e.g. protein purification, preparative chromatography.

The fully automated fraction collector FC1 offers a universal solution for a number of applications requiring the collection of fractions, e.g. protein purification, preparative chromatography or other methods for obtaining samples by fractionation.<blockquote>Price: 4 260<bdi>&nbsp;€ ex VAT</bdi></blockquote>For advanced programming and connection to chromatography software, the device is equipped with a USB interface. FC1 is supported by the <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/305">Clarity Chromatography Station</a><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_schema_procesu_sberu_frakci_pomoci_frakcni_kolektor_FC_1_fa579d59f2/Watrex-schema-procesu-sberu-frakci-pomoci-frakcni-kolektor-FC1.png" alt="Watrex: Schematic of the fraction collection process using the FC1 fraction collector">The robust design of the FC1 ensures reliable X-Y displacement that carries the switching valve. Placing the fraction switch directly above the receiving vessel minimizes dead volume between fractions.Depending on the required volume of fractions, different types of test tube stands are offered with the device. Furthermore, it is also possible to use large-volume containers.The operator controls and programs the fraction collector from the touch screen on the front panel of the device using intuitively arranged screens with adjustable parameters for a given fraction collection series.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Nastaveni_treshold_limitu_pro_sber_frakci_pomoci_sberace_frakci_FC_1_f48d645dfc/Watrex-Nastaveni-treshold-limitu-pro-sber-frakci-pomoci-sberace-frakci-FC1.jpg" alt="Watrex: Setting the treshold limit for fraction collection using the FC1 fraction collector"><h3>FEATURES</h3><ul><li>Simple operation</li><li>Color touch panel control</li><li>Optional analog input</li><li>Selection of rack types</li><li>Clarity CDS supported</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Max. flow: 50 ml/min</li><li>Wetted Materials: PTFE, PEEK</li><li>User control: Color touch panel</li><li>PC connection: USB</li><li>External control: TTL (contact closure) - RUN, STOP, NEXT, COLLECT</li><li>Power supply: 24V DC external power supply</li></ul><h3>Ordering information:</h3><h5>PN/Component:</h5><ul><li>SFC101-001 Streamline™ FC1 Fraction Collector</li><li>SFC101-002 Cooling option for FC1 Fraction Collector</li><li>SFC101-003 Analog Signal Monitoring, Input for FC1 Fraction Collector</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/dedicated-instruments/streamline-fc1-fraction-collector/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex UFO Solvent Recycler

UFO Solvent Recycler saves up to 90% of mobile phase by redirection of the pure solvent to the solvent reservoir during the isocratic HPLC.

This compact device saves up to 90% of mobile phase by redirection of the pure solvent to the solvent reservoir during the isocratic HPLC. The device is powered by 5 V DC from computer USB port or power adapter. Working parameters (Threshold and Delay) are set using user friendly software.<blockquote>Price: 635<bdi>&nbsp;€ ex VAT</bdi></blockquote>The UFO Solvent Recycler continuously monitors the output signal of the chromatography detector and displays its current value in the application on computer. A high-resolution analog-to-digital converter provides data for further evaluation in the built-in processor.If the input signal level exceeds a preset value (Threshold), the UFO recycler will redirect the flow to the waste. When the signal drops, the solvent recycler waits for the transport delay and then switches the mobile phase back to the reservoir. An autosampler injection marker connected to the UFO recycler START input can be used to zero the input signal at the time of injection.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UFO_schema_6a4cdc0ed4/UFO_schema.png" alt="Watrex: Principle and process of mobile phase recycling during isocratic HPLC using the UFO system"><h3>FEATURES</h3><ul><li>Very compact design</li><li>Simple operation</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Detector compatibility: compatible with any HPLC detector</li><li>Connection: 1/16″ O.D. tubing, 1/4″-28 flat bottom fittings</li><li>Maximum pressure: 30 p.s.i./0,2 MPa</li><li>Wetted material: PEEK, PTFE</li><li>Input range: +/- 1 V or +/- 100 mV, user selectable</li><li>Computer connection: USB-A</li><li>TTL/contact closure input: configurable (ZERO, start, valve position)</li><li>Power: 5V DC/&lt;100 mA (power supply or computer USB port)</li><li>User interface: PC Windows based software</li></ul><h3>Ordering information:</h3><h5>PN/Component:</h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/dedicated-instruments/ufo-solvent-recycler-peek-version/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">UFO000-001</a> UFO™ Solvent Recycler , PEEK version</li><li><a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/dedicated-instruments/ufo-solvent-recycler-ptfe-version/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">UFO000-002</a> UFO™ Solvent Recycler , PTFE version</li></ul>

Watrex PCRS-300 Post-column derivatization

The PCRS-300 post-column reaction system is a combination of a precision low-pulse high-pressure pump and thermostat in one unit.

Compact system for post-column derivatization consisting of low-pulse reagent pump with selector valve and tempered reaction chamber for reaction coil.<blockquote>Price: 5 033<bdi>&nbsp;€ ex VAT</bdi></blockquote>A selector valve at the inlet of the pump allows choice between reagent and flushing solvent. The system is controlled through color touch panel placed on the front of main unit.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_PCRS_300_3_d3a79a1a57/Watrex-PCRS-300-3.jpg" alt="Watrex: Schematic of the Watrex PCRS-300 low-pulse pump system for post-column derivatisation"><h3>FEATURES</h3><ul><li>Very low pulse reagent delivery</li><li>Excellent temperature stability</li><li>Heating up to 150°C</li><li>Number of reagent coil options</li><li>Thermal fuse against overheating</li><li>Color touch panel control</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Wetted materials: PEEK, PTFE, HDPE, ruby, sapphire</li><li>Flow rate range: 0,01 – 9,99 ml/min</li><li>Flow rate accuracy: &lt; 2%</li><li>Temperature range: up to 150 °C</li><li>Temperature stability: &lt; +/- 0,1 °C</li><li>Liquid connections: Inlet – 1/8″, 1/4″-28 flat bottom; Outlet – 1/16″, UNF 10-32</li><li>Connections: USB, TTL I/O control (ready out, shutdown in)</li><li>Control: build-in color touch panel</li><li>Dimensions: 310 x 270 x 170 mm (WxDxH, main unit)</li><li>Power requirements: 19-20V DC/4,7A</li></ul><h3>Ordering information:</h3><h5>PN/Component:</h5><ul><li>PCRS300-001 Post Column Reaction System</li><li>PCRS300-002 Reaction coil select from 250µl - 2000µl in Stainless Steel</li><li>PCRS300-003 Reaction coil select from 500µl - 1000µl in PEEK</li><li>PCRS300-004 Reaction coil select from 500µl - 1000µl in PTFE</li><li>PCRS300-999 Reaction coil , customized</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/dedicated-instruments/pcrs-300-post-column-reaction-system-2/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex CTC 330 HPLC Column Oven

Column thermostat CTC-330 for HPLC with a temperature range from 10°C above ambient temperature to 120°C

<a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/column-thermostats/ctc-330-column-oven/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Column thermostat CTC-330 </a>for HPLC with a temperature range from 10°C above ambient temperature to 120°C. Internal dimensions: 490 x 60 x 40 mm (L x W x D). Temperature accuracy 0.5%, temperature stability 0.2 °C. Communication with a computer via the built-in USB interface. CDS Clarity driver is standard part of datasystem installation.<blockquote>Price: 1 559 <bdi>€ ex VAT</bdi></blockquote><h3>FEATURES</h3><ul><li>Excellent temperature stability</li><li>Heating up to 120°C</li><li>Thermal fuse against overheating</li><li>USB interface</li><li>Color touch panel control</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Temperature range: 10 °C above ambient temperature up to 120 °C</li><li>Temperature accuracy: max. 0,5% of actual temperature</li><li>Tempearture stability: &lt; +/-0,1 °C over full operating range</li><li>Settability: 0,1 °C</li><li>Internal dimensions: 490 x 60 x 40 mm (L x W x H)</li><li>Compartment material: black anodized aluminium</li><li>Computer connection: μUSB</li><li>Control: build-in color touch panel</li><li>Power requirements: 19-20V DC/3A</li></ul><h3>Ordering information:</h3><h5>PN/Component:</h5><ul><li>CTC330-001 CTC-330 Column Oven</li></ul>

Watrex Streamline Isocratic HPLC system

Streamline™ isocratic HPLC system consists of one P1 pump, CT1i column thermostat with manual injector and UV1 UV/Vis detector.

Streamline™ isocratic HPLC system consists of one <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/?s=streamline+p1+pump&amp;post_type=product&amp;dgwt_wcas=1?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">P1 pump</a>, <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/column-thermostats/streamline-ct1-columm-thermostat/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">CT1 column thermostat </a>with manual injector and <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/?s=uv1+uv&amp;post_type=product&amp;dgwt_wcas=1?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">UV1 UV/Vis detector</a>. Modular concept offers easy and economical upgrades or configuration modifications such as additional detectors, autosampler or fraction collector.<h3>FEATURES</h3><ul><li>Optimized pump mechanics with parallel piston design offers excellent flow rate accuracy and low pulsation</li><li>Excellent signal-to-noise ratio of the UV1 detector</li><li>Data acquisition, processing and instrument control is done by Clarity Chromatography Station</li></ul><h3>COMPONENT SPECIFICATION</h3><h5>SPECIFICATIONS - P1 HPLC pump:</h5><ul><li>Flow Rates: 0.001 to 10.000 mL/min</li><li>Pressure: 0 to 6,000 psi (42 MPa)</li><li>Flow precision: &gt; 0.2% RSD</li><li>Flow accuracy: ± 1 % @ 1mL/min and 7 MPa,</li><li>Pressure accuracy: ± 2% of full-scale, with 80:20 H2O/IPA @ 7 MPa</li><li>Pulsation: ± 0.5 % @ 1mL/min and 7 MPa</li><li>Remote inputs: USB</li></ul><h5>SPECIFICATIONS - UV1 UV detector:</h5><ul><li>Light Source: Deuterium Lamp, Tungsten Lamp</li><li>Wavelength Range: 190 – 800 nm</li><li>Baseline Noise: 1 x 10-5 AU (@240 nm, 2 sec. risetime)</li><li>Baseline Drift: less than 3 x 10-4 AU/h</li><li>Wavelenghth Reproducibility: ± 0.1 nm</li><li>Linearity: better than 2.5 AU</li><li>Analog Output: 1x 1 V</li></ul><h5>SPECIFICATIONS - CT1 Column thermostat:</h5><ul><li>Temperature range: 10 °C above ambient temperature to 100 °C</li><li>Temperature accuracy: max. 0,5 % of actual temperature</li><li>Temperature stability: RSD &lt; 0,4 %</li><li>Settability: 0,1 °C</li><li>Internal dimensions: 320 x 50 x 30 mm (L x W x H)</li><li>Compartment material: PTFE coated metal</li><li>Compartment connection: USB</li><li>Control: build-in color touch panel, datasystem</li></ul><h5>SPECIFICATIONS - <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity™ Chromatography Station</a>:</h5><ul><li>Advanced data acquisition and evaluation, enables routine separations with pre-set methods for experimental settings. PC Win 10 Professional with LCD monitor included</li></ul><h3>Ordering information:</h3><h5>PN/Component:</h5><ul><li>SSI101-001 Streamline™ isocratic system (Includes P1 pump,UV1 detector, CT1i column thermostat with manual injector, solvent rack, Clarity datastation)</li><li>SUV99-001 Remove UV1 detector from system</li><li>ST99-002 Remove CT1i column thermostat with manual injector from system</li><li>SPDA90-001 Add PDA1 265 photodiode detector to system</li><li>SRI90-001 Add RI1 Refractive index detector to system</li><li>SAS90-001 Add AS1 Autosampler to system</li><li>SFC90-001 Add FC1 Fraction collector to system</li></ul>

Thermo Scientific Vanquish Core HPLC System

The Vanquish Core HPLC systems provide exceptional analytical precision, detector sensitivity, and operational simplicity to enable unprecedented reliability and robustness.

Thermo Scientific™ Vanquish™ Neo UHPLC System

Take advantage of outstanding performance and productivity for all LC-MS workflows with nano-, capillary, and microflow using the Thermo Scientific™ Vanquish™ Neo UHPLC system.

Products focused on HPLC - page 20

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