Breathomics, Asthma & GC×GC: PH Stefanuto on Fighting the “Proof‑of‑Concept” Trap
Article | Interview

Breathomics, Asthma & GC×GC: PH Stefanuto on Fighting the “Proof‑of‑Concept” Trap

Pierre-Hugues Stefanuto and Candi Gokey discuss GC×GC, untargeted metabolomics, breath analysis, AI, and the path from molecular fingerprints to personalized asthma monitoring.
Breathomics, Asthma & GC×GC: PH Stefanuto on Fighting the “Proof‑of‑Concept” Trap
Helium to Hydrogen: What Happens to GC-MS/MS Performance When You Switch Carrier Gas?
Article | Science and research

Helium to Hydrogen: What Happens to GC-MS/MS Performance When You Switch Carrier Gas?

Switching from helium to hydrogen in GC-MS/MS does not necessarily mean losing sensitivity. A study of 181 pesticides shows how method optimization can maintain reliable routine quantitation.
Helium to Hydrogen: What Happens to GC-MS/MS Performance When You Switch Carrier Gas?
The Chemistry of Human Decomposition: GC×GC, Body Farms, and Forensic Science with Dr. Darshil Patel
Article | Interview

The Chemistry of Human Decomposition: GC×GC, Body Farms, and Forensic Science with Dr. Darshil Patel

Darshil Patel discusses his path from dentistry to forensic chemistry and explains how GC×GC–TOF-MS reveals complex VOC profiles from human decomposition and supports human-remains detection.
The Chemistry of Human Decomposition: GC×GC, Body Farms, and Forensic Science with Dr. Darshil Patel
How Mass Spectrometry Actually Works: The Quadrupole Explained
Article | Interview

How Mass Spectrometry Actually Works: The Quadrupole Explained

Dr. Lee Polite explains the fundamentals of GC/MS through memorable analogies, making one of analytical chemistry's most powerful techniques easy to understand.
How Mass Spectrometry Actually Works: The Quadrupole Explained
Lib Search: Cleaning Up Workspace and Temporary HLM Files in NIST26clean up
Article | Academy

Lib Search: Cleaning Up Workspace and Temporary HLM Files in NIST26clean up

Learn how NIST MS Search stores library search history, what HLM files are used for, and how to automatically remove temporary files to keep your workspace clean and organized.
Lib Search: Cleaning Up Workspace and Temporary HLM Files in NIST26clean up
How Separation Science Is Taught vs. How It’s Actually Used
Interview | Scientists

How Separation Science Is Taught vs. How It’s Actually Used

Chemistry educator Natasha Le discusses how students learn separation science, why critical thinking matters more than memorizing procedures, and how future analytical scientists are trained.
How Separation Science Is Taught vs. How It’s Actually Used
Raw Data Files for EI Low Resolution in the Identifications Folder
Article | Academy

Raw Data Files for EI Low Resolution in the Identifications Folder

Discover what the NIST Identification Folder contains during low-resolution EI GC-MS processing. Learn how TIC, ELU, FIN, TSV, RUN, and LOG files support deconvolution and library searching.
Raw Data Files for EI Low Resolution in the Identifications Folder
RI Calibration in NIST26 Chromatogram and Applying to Calculating RI in Samples
Article | Academy

RI Calibration in NIST26 Chromatogram and Applying to Calculating RI in Samples

Learn how to create retention index calibrations in NIST 26, calculate RI values automatically, and improve GC-MS compound identification by combining spectral library searching with retention indices.
RI Calibration in NIST26 Chromatogram and Applying to Calculating RI in Samples
Lib Search: Similarity EI Hybrid Search for Spectra Sent from Chromatogram Window
Article | Academy

Lib Search: Similarity EI Hybrid Search for Spectra Sent from Chromatogram Window

Learn how NIST 26 Hybrid Search expands EI GC-MS library searching by identifying structurally related compounds using mass-shifted fragment matching, DeltaMass analysis, and MS Interpreter validation.
Lib Search: Similarity EI Hybrid Search for Spectra Sent from Chromatogram Window
Normal EI Search for Spectra Sent from Chromatogram Window
Article | Academy

Normal EI Search for Spectra Sent from Chromatogram Window

Learn how to use NIST 26 Lib Search with spectra sent from the Chromatogram Window, compare Full Spectrum and Reverse searches, and improve EI GC-MS identifications.
Normal EI Search for Spectra Sent from Chromatogram Window