<p><strong>Cancer treatment not only damages tumour cells but also changes them. And some of these changes could be used to target treatment more effectively. Scientists from CEITEC Masaryk University and University Hospital Brno have found that during treatment for chronic lymphocytic leukaemia, a receptor becomes more abundant on the surface of cancer cells, making it possible to target them with an antibody. In laboratory experiments, the researchers therefore combined a commonly used drug with an antibody targeting this receptor. The combination killed leukaemia cells significantly more effectively than the drugs alone. The research is still at the preclinical stage, but points to a possible way towards more effective combination cancer therapies.</strong></p><p><strong>Chronic lymphocytic leukaemia (CLL) </strong>is the most common leukaemia in older adults in the Western world. It affects white blood cells called<strong> B lymphocytes</strong>, which begin to multiply uncontrollably and accumulate in the blood, bone marrow and lymph nodes. CLL treatment has changed significantly in recent years. Modern targeted drugs can block signals that cancer cells need to survive and multiply.</p><p>The researchers focused on what happens to leukaemia cells during such treatment. They analysed patient samples collected before and during treatment with <strong>BCR inhibitors</strong>, drugs commonly used to treat CLL. They studied patients receiving two different targeted BCR inhibitors. Although the two drugs affect cancer cells differently, the cells responded to both with surprisingly similar changes.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Leukemicke_bunky_reaguji_na_lecbu_tak_ze_ze_sebe_udelaji_terc_2_8b86014944.jpeg" alt="CEITEC/Miroslav Boudný: Leukaemia Cells Respond to Treatment by Turning Themselves into a Target: Preparation of cells for experiments." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Leukemicke_bunky_reaguji_na_lecbu_tak_ze_ze_sebe_udelaji_terc_2_8b86014944.jpeg 235w," sizes="100vw" width="1600" height="1067"></p><p><i>“Cancer cells are not passive. They respond and adapt to treatment. We wanted to know whether, among the changes triggered by treatment, we could find something that could be used against them. That is what led us to the <strong>CXCR4</strong> receptor,”</i> explains <a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.eu/veronika-sandova-ph-d/u95494?page=publication"><strong>Veronika Šandová</strong></a>, a researcher&nbsp;from <strong>Marek Mraz’s laboratory at CEITEC Masaryk University and University Hospital Brno</strong>.</p><p>CXCR4 is a receptor on the cell surface that, among other functions, helps leukaemia cells move to environments that provide favourable conditions for their survival. The researchers found that once treatment begins, CXCR4 levels on the surface of cancer cells increase significantly. The way cancer cells respond to treatment could therefore also become a weakness. Molecules on the cell surface are readily accessible to targeted treatment using specific antibodies.</p><p>In laboratory experiments, the researchers therefore added <strong>ulocuplumab</strong>, an antibody that binds to the CXCR4 receptor, to the drugs already being used. The effect was substantial. While around seven out of ten leukaemia cells survived treatment with the drugs alone, only around <strong>three to four out of ten survived</strong> when the drugs were combined with the antibody. <i>“It is a little like a cancer cell adapting against the first attack and, in doing so, marking itself as a target for a second one. The treatment increases the amount of a particular molecule on its surface, which we can then target,”</i> Veronika Šandová explains.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Leukemicke_bunky_reaguji_na_lecbu_tak_ze_ze_sebe_udelaji_terc_3_a3d50f3f82.jpeg" alt="CEITEC/Miroslav Boudný: Leukaemia Cells Respond to Treatment by Turning Themselves into a Target: Cooling the cells after the experiment prevents degradation of protein and other molecules." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Leukemicke_bunky_reaguji_na_lecbu_tak_ze_ze_sebe_udelaji_terc_3_a3d50f3f82.jpeg 235w," sizes="100vw" width="1600" height="1067"></p><p>The researchers went on to verify the results in a <strong>mouse model </strong>using leukaemia cells from patients. Here, too, the antibody targeting CXCR4 was highly effective at eliminating the cancer cells.</p><p>The research is still at the<strong> preclinical stage</strong>, so this is not a new treatment that can yet be offered to patients. However, it suggests a possible way to identify more effective combinations of cancer drugs. <i>“With cancer, targeting a single mechanism is often not enough because cancer cells can respond to treatment and find other ways to escape and survive. Our results show that we can use these changes to our advantage and target them with additional treatment,”</i> says<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.eu/prof-marek-mraz-ph-d/u26692"><strong>Marek Mráz</strong></a>, head of the research laboratory where the study was conducted.</p><p>The study therefore offers another perspective on the search for new combinations of cancer treatments: looking not only at whether a drug kills a cancer cell, but also at how it changes the cell – and whether any of these changes could provide a new target for further treatment.</p><p>The study was conducted in collaboration among scientists from <strong>CEITEC Masaryk University</strong>, <strong>University Hospital Brno</strong>, the<strong> Faculty of Medicine at Masaryk University</strong>, and the<strong> Dana-Farber Cancer Institute in Boston</strong>.</p><p>The results were published in the scientific journal <a target="_blank" rel="noopener noreferrer" href="https://onlinelibrary.wiley.com/doi/10.1002/hem3.70481"><i><strong>HemaSphere</strong></i></a>.</p><blockquote><h4><strong>The original article</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://onlinelibrary.wiley.com/doi/10.1002/hem3.70481"><strong>Gene expression analysis after BTK and PI3Kδ inhibitor treatment in chronic lymphocytic leukemia identifies cell-surface CXCR4 as a synergistic target for combinatorial therapy</strong></a></h4><p>Gabriela Mladonicka Pavlasova, Veronika Sandova, Laura Ondrisova, Vaclav Seda, Petra Pavelkova, Daniel Filip, Krystof Hlavac, Josef Vecera, Sarka Pospisilova, Anna Panovska, Stacey M. Fernandes, Michael Doubek, Jennifer R. Brown, Marek Mraz</p><p><span>HemaSphere</span> <span>(2026) 10 (9): e70481</span></p><p><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1002/hem3.70481">https://doi.org/10.1002/hem3.70481</a></p><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><p>Marek Mráz’s research group is part of the <strong>National Institute for Cancer Research </strong>(<a target="_blank" rel="noopener noreferrer" href="https://www.nuvr.cz/en/"><strong>NICR</strong></a>).</p>

Leukaemia Cells Respond to Treatment by Turning Themselves into a Target

News from LabRulezLCMS Library - Week 44, 2026

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 26th October 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><h3><strong>1. Agilent Technologies: Ultratrace Analysis of Surface Impurities in Photovoltaic-Grade Polysilicon by ICP-MS</strong></h3><p><strong>Quantification of 58 elements per GB/T24582-2023 using an </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=8900"><strong>Agilent 8900 ICP-QQQ</strong></a></p><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_photovoltaic_cells_polysilicon_8900_icp_qqq_5995_0020en_agilent_2125536f4e.pdf"><strong>Full PDF for download</strong></a><strong>&nbsp;</strong></li></ul><p>Green and sustainable energy reduces environmental harm, lowers carbon emissions, and supports long-term ecological balance.1 As energy demand rises and climate impacts intensify, transitioning from fossil fuels to renewable sources, such as solar, wind, hydro, geothermal, and biomass, has become essential for sustainability and energy security.2 Solar energy is widely used through technologies such as photovoltaic (PV) cells, which convert sunlight into electricity, and solar thermal systems, which produce heat. PV cells, which are typically made from crystalline silicon, are key to solar technology. The efficiency, cost, and durability of the cells largely depend on the materials used.3,4&nbsp;</p><p>PV architectures are fundamentally built upon high-purity silicon ingots— a monocrystalline or polycrystalline mass of semiconductor-grade silicon, typically formed via the Czochralski or directional solidification process.5 These ingots are sliced into thin wafers that serve as the substrate for solar cell fabrication. In this process, doped regions and junctions are engineered to facilitate charge carrier separation and enable the conversion of incident solar radiation into electrical energy via the PV effect.6 Figure 1 depicts the manufacturing process for a PV panel.</p><p>The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=8900"><strong>Agilent 8900 Triple Quadrupole ICP-MS (ICP-QQQ)</strong></a> is an advanced analytical platform engineered for ultratrace elemental analysis in high-purity materials such as polysilicon used in PV manufacturing. Its unique tandem mass spectrometry (MS/MS) configuration—comprising two quadrupoles (Q1 and Q2) separated by a collision/reaction cell—enables exceptional control over ion selection and reaction chemistry. Q1 acts as a mass filter to isolate target precursor ions, allowing only specific m/z values into the cell, while Q2 analyzes product ions formed after controlled reactions with gases such as O2, H2, or NH3. This design effectively eliminates complex spectral interferences, including polyatomic and isobaric overlaps that are particularly problematic in high-silicon matrices. As a result, the 8900 achieves sub-parts-per-trillion (ppt) detection limits for critical impurities like alkali and alkaline earth elements that are otherwise difficult to quantify accurately using conventional ICP-MS. Also, its high sensitivity, wide dynamic range, and robust plasma conditions ensure reliable quantification across varying concentration levels. These capabilities make the 8900 ICP-QQQ a useful instrument for QC and contamination monitoring in the semiconductor and solar industries, where even trace impurities can significantly impact PV cell efficiency and performance.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>An Agilent 8900 ICP‑QQQ, configured with an s‑lens ion optics system to enhance ion transmission efficiency and sensitivity, was used for the simultaneous quantification of 58 trace and ultratrace elements in two polycrystalline silicon ingot samples. Sample preparation was carried out by acid extraction in accordance with the GB/T 24582‑2023 standard.&nbsp;</p><p>Ultratrace detection at sub‑ppt levels was achieved using MS/MS (triple quadrupole) mode, utilizing multiple reaction gases to systematically mitigate spectral interferences via mass‑shift and on‑mass reaction pathways. This approach enabled selective removal of polyatomic interferences commonly associated with silicon matrices, thereby improving analyte selectivity and lowering background noise. The method exhibited strong analytical precision, with relative standard deviations (RSDs) below 10% across six replicate measurements, indicating consistent signal stability, efficient interference control, and robust instrumental performance.&nbsp;</p><p>The 0.1 µg/L spike‑recovery results within ± 20% confirmed the accuracy of the quantification. The internal standard recoveries verified stable instrument performance and effective correction for matrix‑induced signal variation, further supporting reliable multi‑element analysis of high‑purity silicon. This level of reliability is essential for maintaining accuracy at sub‑ppb levels in challenging silicon matrices.&nbsp;</p><p>The 8900 ICP-QQQ method is well aligned with the demands of advanced manufacturing environments. It is particularly suited to PV production, where precise and reproducible impurity monitoring is vital for ensuring material quality, optimizing process control, and preserving device performance.</p><h3><strong>2. LECO: Metallography of Aluminum and Aluminum Alloys</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/METALLOGRAPHY_ALUMINUM_ALUMINUM_ALLOY_203_821_722_c024278c37.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Aluminum has become a widely used material due to its natural corrosion resistance (oxide layer), manageable weight, high thermal conductivity, and cost-effective machinability. Pure Aluminum is too soft for structural use, so it is often alloyed with other metals such as Copper, Magnesium, Silicon, Zinc, and Manganese to increase its strength and durability for aerospace, automotive, and construction applications. Metallography is an important tool for verifying quality control properties in these materials, including grain size, intermetallic phases, precipitates, and porosity, all of which affect mechanical properties, corrosion resistance, and electrical conductivity. LECO offers complete metallographic solutions made to streamline and optimize every step of the sample preparation process from start to finish.</p><h4><strong>Sample Sectioning&nbsp;</strong></h4><p>With any metallographic sample, the most critical step of sample preparation is sectioning. The goal of sectioning is to remove a suitable-sized sample from a larger component with the least amount of deformation. If done incorrectly, thermal damage may occur to the sample's surface, requiring extra steps in the grinding/polishing phase. It could even affect the sample's microstructure, resulting in skewed image analysis results. In extreme cases, it may even require an operator to resection the sample, leading to additional costs and loss of valuable time. To increase efficiency, it is important to choose the correct blade and fixture for your sample.&nbsp;</p><p>LECO recommends the use of a Silicon Carbide blade (SiC) for sectioning Aluminum alloys, as they are designed for soft non-ferrous metals, allowing minimal deformation and efficient heat dissipation. The SiC abrasives prevent smearing and tearing, outperforming harder Iron-focused blades on Aluminum structure. LECO offers a variety of fixturing options to accommodate even the most difficult geometries for sectioning (Figures 4 and 5). Fixturing the sample properly is critical to stabilize the sample to prevent unnecessary vibrations and release of the sample during the cutting process.&nbsp;</p><p>If thermal degradation occurs after taking these necessary measures, it could be the sectioning method. Although chop cutting (Z-Axis) is the traditional form of operation with sectioning saws, it may be advantageous to try a pulse or planar cut that would provide more relief in the process. This could also be the case for an Aluminum part with complex geometry.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>In summary, Aluminum and its alloys remain essential to modern engineering due to their lightweight nature, corrosion resistance, and adaptability. Ensuring these materials meet the demanding requirements of aerospace, automotive, and structural applications depends on precise metallographic evaluation. By characterizing grain structures, intermetallic phases, precipitates, and porosity, metallography provides critical insight into material performance, durability, and quality.&nbsp;</p><p>LECO supports this process with a full suite of metallographic solutions designed to enhance efficiency and consistency at every stage of preparation. From robust sectioning systems that ensure clean, controlled cuts, to reliable mounting equipment that protects and preserves sample integrity, LECO enables repeatable, high-quality preparation. Our advanced grinding and polishing platforms deliver uniform, scratch-free surfaces ready for evaluation, while our comprehensive image analysis software provides accurate, data-driven characterization of microstructural features. Together, these tools offer a streamlined, end-to-end workflow that empowers laboratories to maintain stringent quality control and achieve confident, repeatable results.</p><h3><strong>3. Shimadzu: Analysis of Trace and Major Elements in Steel by ICP-AES</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_01_01072_en_736a917a5f.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User benefits</strong></h5><ul><li>The ICPE-9820 enables analysis across a wide concentration range, from trace to major elements in steel.&nbsp;</li><li>Using a torch for high-salt samples and a water bubbler can suppress salt deposition when analyzing high-salt samples.&nbsp;</li><li>The use of a vacuum spectrometer enables rapid startup and quick analysis in the vacuum ultraviolet region (wavelengths below 190 nm).</li></ul><p>Steel materials are widely used in a diverse range of industries, including construction, transportation, and machinery manufacturing, and are indispensable in modern society. Steel contains various elements, and the types and concentrations of these elements significantly influence its properties. Accordingly, elemental analysis is essential for quality assurance and performance control.&nbsp;</p><p>The elements in steel range from trace constituents to major components, with concentrations spanning a broad range from mg/L levels to percentage levels. Inductively coupled plasma atomic emission spectrometry (ICP-AES) is well suited to the analysis of elements across such a wide concentration range. It enables highly accurate quantitative analysis from trace elementsto major components.&nbsp;</p><p>This Application News presents an analysis example of a stainless-steel certified reference material using the Shimadzu ICPE-9820 multi-type ICP atomic emission spectrometer.</p><h4><strong>Analysis Conditions&nbsp;</strong></h4><p>The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=1&amp;search=ICPE-9820"><strong>ICPE-9820</strong></a><strong> </strong>enables simultaneous analysis using two view orientations: axial view (AX), which offers higher sensitivity, and radial view (RD), which is suitable for high-concentration analysis.&nbsp;</p><p>For major element analysis, quantification was performed using the calibration curve method with the internal standard method. For trace element analysis, quantification was performed using the standard addition method.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>In this Application News, trace and major elements in a stainless-steel certified reference material were analyzed using the ICPE-9820. The measured values showed good agreement with the certified values.&nbsp;</p><p>The sample introduction system, consisting of a torch for highconcentration salt solution samples and a water bubbler, effectively prevented sensitivity loss from salt deposition. At the same time, the use of a Twister spray chamber enabled finer particle-size selection, thereby improving analytical accuracy for high-salt samples.&nbsp;</p><p>In addition, the ICPE-9820 employs a vacuum spectrometer, enabling rapid startup and fast analysis in the vacuum ultraviolet region (wavelengths below 190 nm).</p><h3><strong>4. Thermo Fisher Scientific: Rapid, accurate field analysis of phosphate ores with handheld XRF</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/field_analysis_of_phosphate_ores_an1912_en_b0cb5ab9ec.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>The need for rapid phosphate ore analysis&nbsp;</strong></h5><p>Phosphate rock (phosphorite) is the primary source of phosphorus used in fertilizers, making it indispensable to global food production. As high-grade phosphorite deposits become increasingly depleted, mining operations must process lower-grade and more compositionally variable phosphate ores. This trend places greater emphasis on rapid, accurate elemental analysis to support exploration, grade control, process optimization, and compliance with environmental regulations. Handheld X-ray fluorescence (HHXRF) has become a key analytical tool for these applications by providing fast, non-destructive, multi-element analysis directly in the field or at the production site.</p><h5><strong>Handheld XRF for rapid phosphate ore analysis&nbsp;</strong></h5><p>Handheld X-ray fluorescence (HHXRF) analyzers have emerged as valuable tools for on-site elemental analysis of the major and penalty elements in phosphate ores. The analyzers’ portability, ease of use, and ability to deliver analytical results within seconds make them ideal for rapid decision-making in mining exploration as well as mining operations for guiding extraction, stockpile management, quality control and environmental monitoring. While handheld XRF does not replace laboratorygrade analysis for certification purposes, it provides immediate compositional information that can significantly improve operational efficiency.&nbsp;</p><p>The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1992"><strong>Thermo Scientific™ Niton™ XL5 Plus Handheld XRF Analyzer </strong></a>(Figure 1a) combines a compact, lightweight design with advanced analytical performance for field-based elemental analysis. Featuring a 5 W / 50 kV / 500 µA max. proprietary X-ray tube and a large-area silicon drift detector (SDD) with a graphene window, the Niton XL5 Plus analyzer delivers accurate elemental analysis across all stages of mining and exploration. The Mining Mode on the XL5 Plus analyzer can measure 41 elements, from magnesium (Mg) to uranium (U), using four optimized excitation conditions to enhance the signal-to-noise ratios of fluorescence lines across the full energy spectrum. Mining Mode uses a proprietary fundamental parameter (FP) based algorithm that accounts for the high variability of sample composition by correcting for matrix absorption and secondary enhancement effects; this improves analytical accuracy across a wide range of sample compositions. Users can optimize settings of Mining Mode and store that group of preferred settings under Profiles. Profiles enable users to have multiple analytical methods on the same instrument; the most appropriate profile for a given task can be easily selected to perform desired measurements quickly.</p><h4><strong>Key findings&nbsp;</strong></h4><p>The Niton XL5 Plus handheld XRF analyzer provides rapid, accurate, multi-element analysis of phosphate ores, enabling informed decision-making throughout exploration, mining, and fertilizer production. Combined with appropriate sample preparation, the analyzer delivers excellent agreement with certified laboratory values for both major constituents and critical penalty elements such as uranium and cadmium. By providing immediate analytical results at the point of need, the Niton XL5 Plus analyzer helps improve ore characterization, optimize process control, and reduce reliance on timeconsuming laboratory analyses.</p>

News from LabRulezICPMS Library - Week 44, 2026

Article

Application

Science and research

Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

CEITEC

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LabRulez

LECO Tube Furnaces

LECO Cornerstone TF Tube Furnaces deliver high-temperature crucible baking up to 1350 °C, reducing contamination, improving carbon and sulfur accuracy, and cutting energy costs by up to 60%.

<p><strong>The LECO Cornerstone TF Tube Furnaces are versatile, energy-efficient resistance furnaces designed to bake crucibles and significantly reduce contaminants that can interfere with carbon and sulfur analytical results. Engineered for both high- and lower-volume laboratories, the TF series improves data accuracy, repeatability, and operating efficiency while reducing overall energy consumption.</strong></p><h4><strong>Key Features</strong></h4><ul><li>Long-life <strong>molybdenum disilicide heating elements</strong> with an operating temperature range from <strong>800 °C to 1350 °C</strong></li><li><strong>Integrated digital furnace controller</strong> displaying set point or actual temperature with built-in overtemperature protection</li><li><strong>TF4 Quad Tube Furnace</strong><ul><li>Six heating elements</li><li>Enables simultaneous baking of crucibles in <strong>four combustion tubes</strong></li><li>Ideal for demanding, high-volume installations supporting <strong>two to four analytical units</strong></li></ul></li><li><strong>TF2 Dual Tube Furnace</strong><ul><li>Four heating elements</li><li>Efficient solution for lower-volume laboratories supporting <strong>one to two systems</strong></li></ul></li><li>Increased crucible capacity and optimized furnace design deliver up to <strong>60% lower energy consumption</strong> compared to previous models, significantly reducing operating costs</li></ul><h4><strong>Impact of Crucible Preheating on Analytical Results</strong></h4><p>Preheating crucibles in the TF furnaces has a pronounced effect on carbon and sulfur accuracy. When 528-018 crucibles were baked at <strong>1250 °C for 15 minutes</strong>, results for a high-purity iron reference material (certified at 5 ppm carbon and 2 ppm sulfur) showed dramatically improved accuracy and reduced variability.</p><ul><li><strong>Baked crucibles</strong> produced results close to certified values with low standard deviation</li><li><strong>Unbaked crucibles</strong> showed elevated carbon and sulfur levels</li><li><strong>Baked but touched crucibles</strong> demonstrated significant contamination, highlighting the importance of proper handling after baking</li></ul><p>These results confirm that controlled crucible baking is essential for achieving low-level carbon and sulfur determinations with confidence.</p><h4><strong>Energy Efficiency</strong></h4><p>The redesigned TF furnaces use approximately <strong>60% less energy</strong> than previous models. At continuous operation with a full crucible load and a furnace temperature of <strong>1350 °C</strong>, operating cost comparisons clearly demonstrate substantial savings in power consumption, making the TF series both an analytical and economic advantage for modern laboratories.</p><h4><strong>Models</strong></h4><ul><li><strong>TF4</strong> – Quad Tube Furnace</li><li><strong>TF2</strong> – Dual Tube Furnace</li></ul>

LECO BG Series Belt Grinder for Metallographic Sample Polishing

The LECO BG Series belt grinders provide durable, safe, and flexible wet or dry grinding for metallographic and spectrographic sample preparation in single- or dual-belt configurations.

<p><strong>The BG Series belt grinders are designed to deliver durable, safe, and convenient grinding performance for metallographic and spectrographic sample preparation. Available in both single-belt and dual-belt configurations, the BG Series supports efficient material removal while maintaining operator safety and consistent results.</strong></p><p>By combining the grinder with an optional dust collector or a recirculating system, the BG Series can be configured for either dry or wet grinding, making it a flexible solution for a wide range of laboratory workflows. Its robust construction and straightforward operation make it well suited for routine use in production, quality control, and research laboratories.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_BG_Pasova_bruska_pro_lesteni_metalografickych_vzorku_5_adfd9793f2.jpg" alt="LECO: BG Series Belt Grinder for Metallographic Sample Polishing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_BG_Pasova_bruska_pro_lesteni_metalografickych_vzorku_5_adfd9793f2.jpg 245w," sizes="100vw" width="1303" height="691"></p><h4><strong>Key Features</strong></h4><ul><li>Heavy-duty 1 HP (0.75 kW) motor for reliable and consistent grinding performance</li><li>Enclosed belt tension mechanism that prevents belt slippage and improves coolant and debris drainage</li><li>Integrated safety guards to maximize operator protection during operation</li><li>Corrosion-resistant aluminum external surfaces for long service life in laboratory environments</li></ul><h4><strong>Available Models</strong></h4><ul><li><strong>BG30</strong> – Single belt drive configuration</li><li><strong>BG32</strong> – Dual belt drive configuration</li></ul>

LECO SX100 Benchtop Metallographic Saw

SX100M benchtop sectioning machine delivers precise and safe cutting of metals, carbides, composites, and electronic components with a powerful motor and compact, ergonomic design.

<p><strong>The SX100M is an efficient benchtop sectioning machine designed to handle a wide range of materials and applications with precision and reliability. It is an ideal solution for sectioning bar stock, castings, fasteners, tungsten carbide, composite materials, electronic components, weldments, and more. With an approximate maximum sample cut diameter of 2.75 inches, the SX100M delivers dependable performance in a compact laboratory-friendly footprint.</strong></p><p>Equipped with a powerful 3 HP (2.2 kW) motor and a 10-inch (250 mm) blade capacity, the SX100M ensures consistent cutting results even for demanding materials. An integrated electronic mechanical braking system enhances operator safety and improves workflow efficiency.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_SX_100_Stolni_metalograficka_pila_83b2b057c2.jpg" alt="LECO: SX100 Benchtop Metallographic Saw" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_SX_100_Stolni_metalograficka_pila_83b2b057c2.jpg 158w," sizes="100vw" width="1185" height="1175"></p><h4><strong>Key Features</strong></h4><ul><li>Radial arm design for manual operation with an ergonomic, user-friendly working height</li><li>Base aluminum casting combined with a steel hood for durability and long service life</li><li>Integrated safety lock to protect the operator during sectioning</li><li>Built-in 6.6-gallon (25 L) recirculating coolant tank</li><li>Sloped interior floor for efficient coolant flow and reduced debris accumulation</li><li>Electronic mechanical braking system for rapid and safe blade stopping</li></ul><h4><strong>Models</strong></h4><h5><strong>SX100M</strong></h5><ul><li>Power supply options: 230 V or 400 V</li></ul>

LECO PX300 Manual Grinder/Polisher for Metallographic Sample Preparation

PX300 grinder/polisher delivers simple operation and reliable specimen preparation for microhardness and microstructural analysis, offering a compact and durable solution for low-volume metallography labs.

<p><strong>The PX300 Grinder/Polisher Series is designed to emphasize ease of use while consistently producing specimens that are ideal for microhardness testing and microstructural examination. Engineered as an efficient, safe, reliable, and clean solution, the PX300 is particularly well suited for lower-volume metallography laboratories that still demand high-quality, reproducible results.</strong></p><p>With a compact design and durable construction, the PX300 delivers dependable grinding and polishing performance while minimizing operator effort and routine maintenance.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PX_300_Rucni_bruska_lesticka_pro_pripravu_metalografickeho_vzorku_2_ac80a9624c.jpg" alt="LECO: PX300 Manual Grinder/Polisher for Metallographic Sample Preparation" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PX_300_Rucni_bruska_lesticka_pro_pripravu_metalografickeho_vzorku_2_ac80a9624c.jpg 244w," sizes="100vw" width="764" height="489"></p><h4><strong>Key Features</strong></h4><ul><li>Spiral bowl design with an automatic bowl wash system to prevent drain clogs and simplify cleanup</li><li>Emergency Stop button for immediate shutdown of grinding operations and enhanced operator safety</li><li>Rugged structural and electronic components designed to withstand demanding laboratory environments</li><li>Clean and reliable grinding/polishing performance suitable for routine metallographic preparation</li></ul><h5><strong>Optional Non-Motorized Head (available at purchase or retrofit)</strong></h5><ul><li>Enables processing of multiple samples simultaneously</li><li>Improves consistency between operators and from run to run</li><li>Enhances throughput and reproducibility in routine applications</li></ul><h4><strong>Models</strong></h4><ul><li><h5><strong>PX300 (Base Model)</strong></h5><ul><li>Power supply: 115 V or 230 V</li></ul></li><li><h5><strong>PX300 (with Non-Motorized Head)</strong></h5><ul><li>Power supply: 115 V or 230 V</li></ul></li></ul><h4><strong>Options</strong></h4><ul><li>Grinding/polishing wheel sizes:<ul><li>8 in</li><li>10 in</li><li>12 in</li><li>200 mm</li><li>250 mm</li><li>300 mm</li></ul></li></ul>

LECO PX Series Automated Metallographic Grinding and Polishing

PX400 and PX500 grinders/polishers deliver easy operation, automated workflows, and reproducible flat specimens with intuitive touch-screen control and advanced cleaning and fluid dispensing features.

<p><strong>The PX400 and PX500 grinders/polishers are designed to emphasize ease of use while consistently delivering exceptionally flat, high-quality specimens. Built with the latest technology, the PX Series provides an efficient, safe, reliable, and clean grinding and polishing solution that helps keep metallography laboratories running smoothly, even in high-throughput environments.</strong></p><p>With an intuitive software interface and a range of smart, operator-focused features, the PX400 and PX500 simplify daily grinding and polishing workflows while ensuring excellent reproducibility across a wide variety of materials and applications.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_PX_Automatizovane_metalograficke_brouseni_a_lesteni_e46f4bd31d.jpg" alt="LECO: PX Series Automated Metallographic Grinding and Polishing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_PX_Automatizovane_metalograficke_brouseni_a_lesteni_e46f4bd31d.jpg 168w," sizes="100vw" width="800" height="743"></p><h4><strong>Key Features</strong></h4><ul><li>Intuitive touch-screen software with practical tools that simplify grinding and polishing workflows</li><li>Innovative spiral bowl design with an automatic bowl wash system to prevent drain clogs and reduce cleanup</li><li>Slow wheel indexing after cycle completion for easy and safe mount removal</li><li>Individual sample mode with slow holder rotation to simplify mount loading</li><li>More than 30 proven, built-in preparation methods, with the ability to create or download additional methods</li><li>Models available for both fixed-force and individual sample preparation</li><li>Support for up to five programmable, metered fluid dispensers to deliver consistent suspensions and extenders for precise polishing results</li></ul><h4><strong>Models</strong></h4><ul><li><h5><strong>PX400A (Automated)</strong></h5><ul><li>Wheel sizes: 8 in, 10 in, 200 mm, 250 mm</li><li>Power supply: 115 V (PX400A1) or 230 V (PX400A2)</li></ul></li><li><h5><strong>PX400S (Standard)</strong></h5><ul><li>Wheel sizes: 8 in, 10 in, 200 mm, 250 mm</li><li>Power supply: 115 V (PX400S1) or 230 V (PX400S2)</li></ul></li><li><h5><strong>PX500A (Automated)</strong></h5><ul><li>Wheel sizes: 10 in, 12 in, 250 mm, 300 mm, 350 mm</li><li>Power supply: 230 V</li></ul></li></ul>

LECO MX Series Metallographic Sample Mounting Presses

MX400 and MX500 are fully automatic mounting presses with a compact design, touch-screen control, customizable methods, and dual-mount capability for fast, reliable metallographic sample preparation.

<p><strong>The MX400 and MX500 are fully automatic mounting presses designed to accelerate and simplify metallographic sample preparation. With a slim, space-saving 8-inch-wide footprint and an intuitive touch-screen interface, these systems deliver faster mounting cycles, higher throughput, and greater flexibility for a wide range of sample types and mounting materials.</strong></p><p>Both systems combine robust mechanical design with advanced process control, allowing laboratories to create reproducible, high-quality mounts while minimizing operator effort. The MX400 and MX500 are ideal solutions for laboratories looking to remove mounting bottlenecks and improve overall preparation efficiency.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_MX_Fixacni_lisy_pro_metalograficke_vzorky_3_8b3f6d935c.jpg" alt="LECO: MX Series Metallographic Sample Mounting Presses" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_MX_Fixacni_lisy_pro_metalograficke_vzorky_3_8b3f6d935c.jpg 193w," sizes="100vw" width="887" height="717"></p><h4><strong>Key Features</strong></h4><ul><li>Durable solid-steel crossbar closure design that resists wear, avoids jamming, and allows quick, one-handed operation</li><li>Easy-to-use swipe-and-touch user interface for intuitive selection of heating, cooling, and pressure parameters</li><li>Fully customizable mounting methods, with the option to use preconfigured LECO-developed methods</li><li>Variable operating modes optimized for delicate samples and compatible with all common mounting materials</li><li>Low thermal mass design enabling rapid heating and cooling for increased productivity</li><li>Full-size dual mounting capability to reduce bottlenecks and increase sample throughput</li><li>Supports mold sizes of 1.25 inch, 1.50 inch, 30 mm, 40 mm, and 50 mm</li><li>Quick and simple mold size changes on the MX500 model</li></ul><h4><strong>Models</strong></h4><ul><li><h5><strong>MX400</strong></h5><ul><li><strong>Supported mold sizes: </strong>1.25 in, 1.5 in, 30 mm, 40 mm, 50 mm</li><li><strong>Power supply: </strong>115 V or 230 V</li></ul></li><li><h5><strong>MX500</strong></h5><ul><li><strong>Supported mold sizes:</strong> 1.25 in, 1.5 in, 30 mm, 40 mm, 50 mm</li><li><strong>Power supply: </strong>115 V or 230 V</li><li>Designed for rapid and easy switching between mold sizes</li></ul></li></ul>

LECO MSX Series Metallographic Sectioning

LECO MSX Series sectioning machines provide precise, reliable cutting from small components to large hardened samples, offering robust construction, flexible fixturing, and manual or automated operation.

<p><strong>The LECO MSX Series of metallographic sectioning machines is designed to meet the needs of laboratories handling samples ranging from very small components to large, hardened parts. With robust construction, precise spindle designs, and flexible fixturing options, the MSX Series delivers reliable, accurate sectioning for routine and demanding metallographic applications.</strong></p><h4><strong>MSX205 – Compact Benchtop Sectioning Machine</strong></h4><p>The MSX205 is an ideal solution for preparing small sections such as electronic components, fasteners, and similar parts. This space-efficient benchtop system supports both linear and radial feed configurations while delivering precise, controlled sectioning.</p><h5><strong>Key Features</strong></h5><ul><li>Advanced spindle design for long service life and precise cuts</li><li>Welded steel construction suitable for demanding lab environments</li><li>Large T-slotted table for fast, flexible sample fixturing</li><li>Channeled coolant drainage to maintain high flow and reduce debris buildup</li><li>Integrated 4.2-gallon (16 L) recirculating coolant system</li><li>Optional integrated Y-table for convenient parallel sectioning</li></ul><h5><strong>Technical Highlights</strong></h5><ul><li>Blade capacity: 8 in (200 mm)</li><li>Motor power: 2.04 HP (1.5 kW), variable speed</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_MSX_Metalograficke_rezani_cc0a792e52.jpg" alt="LECO: MSX205" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_MSX_Metalograficke_rezani_cc0a792e52.jpg 183w," sizes="100vw" width="1930" height="1641"></p><h4><strong>MSX305A – Automated Sectioning for Large Samples</strong></h4><p>The MSX305A Series is engineered for sectioning large and challenging samples, including induction-hardened parts, tool steels, and carburized components. Automated oscillation and servo-pulse sectioning improve cut quality and repeatability across a wide range of materials.</p><h5><strong>Key Features</strong></h5><ul><li>Production-grade spindle supporting up to 14 in (350 mm) blades with 1.25 in (32 mm) arbor</li><li>Heavy-duty welded steel construction</li><li>Manually adjustable Y-axis table for accurate sample positioning and parallel sectioning</li><li>Optional catch basket for small sectioned samples</li><li>Large 15.75 × 15.75 in (400 × 400 mm) T-slotted table and spacious sectioning compartment</li><li>Integrated 30-gallon (115 L) coolant tank with level gauge</li><li>Sealed electronics enclosure with removable side access ports</li><li>Intuitive control panel with dual 5.6 in (142 mm) displays</li></ul><h5><strong>Control and Motion Options</strong></h5><ul><li>Z-axis for manual sectioning (MSX305A1 Series)</li><li>Joystick control for pulse sectioning, blade direction, table direction, and oscillation</li><li>Manual sectioning available on MSX305A2 Series</li></ul><h5><strong>Technical Highlights</strong></h5><ul><li>Motor power: 10.05 HP (7.5 kW)</li></ul><h4><strong>MSX305R – Manual Sectioning for Large Samples</strong></h4><p>The MSX305R Series provides a robust, manually controlled solution for sectioning large samples across a broad range of materials. Its solid construction and flexible table design make it well suited for production and research environments.</p><h5><strong>Key Features</strong></h5><ul><li>Production-grade spindle supporting up to 14 in (350 mm) blades</li><li>Welded steel construction for long-term durability</li><li>Optional catch basket for retaining small cut samples</li><li>15.75 × 15.75 in (400 × 400 mm) T-slotted table with large sectioning area</li><li>30-gallon (115 L) built-in coolant tank with level indicator</li><li>Sealed electronics enclosure with removable side ports</li><li>Easy-to-use control panel</li><li>Z-axis locking feature</li><li>Handwheel-driven X- and Y-table for longitudinal sectioning and precise positioning</li></ul><h4><strong>MSX432 – High-Power Sectioning for Hardened and High-Alloy Materials</strong></h4><p>The MSX432 Series is designed for demanding applications involving large, hardened, or high-alloy materials. Short contact times combined with intense cooling provide true cold-cutting performance, preserving microstructural integrity for metallographic examination.</p><h5><strong>Key Features</strong></h5><ul><li>Advanced spindle design for precise, long-life operation</li><li>Heavy-duty welded steel construction for production environments</li><li>Large T-slotted table for versatile sample fixturing</li><li>Channeled coolant drainage for high flow rates and minimal debris accumulation</li><li>Integrated Y-table for accurate parallel sectioning</li><li>Isolated table design to prevent contamination of linear slides</li><li>High-capacity 39-gallon (150 L) recirculating coolant system</li></ul><h5><strong>Technical Highlights</strong></h5><ul><li>Blade capacity: 17 in (431.8 mm)</li><li>Motor power: 20.1 HP</li></ul>

Organomation 24 Position N-EVAP Nitrogen Evaporator

The 24 position N-EVAP is our most adaptable benchtop evaporator. The basic model offers all of the standard features from our N-EVAP line. Additionally, the 24 position N-EVAP offers the most customizable options for your sample preparation needs. 

<p><strong>The 24 position N-EVAP is our most adaptable benchtop evaporator. The basic model offers all of the standard features from our N-EVAP line. Additionally, the 24 position N-EVAP offers the most customizable options for your sample preparation needs. The standard sample holder can accommodate samples with an outside diameter of 10-30 mm. However, with the optional 8 position large sample holder, vials with an outside diameter of 30-70 mm can be processed. The 24 position N-EVAP test tube evaporator can also be upgraded to include digital controls for heat and time with the addition of the side control box (Option code -CB).</strong></p><p>These economical units provide controlled concentration of sample vials through the application of nitrogen gas within a heated water bath. The dual band spring hoist assembly provides a simple and effective means of removing samples from the heated water bath. The N-EVAP’s circular rotating design permits each sample to be accessible from the front of the instrument for easy insertion and retrieval. The chrome plated needle valves are individually milled from solid brass, enabling precise, uniform adjustments for your nitrogen blow down. This promotes efficient and safe sample reduction with minimal nitrogen waste. Time tested technology and proven construction ensure a long lasting, user-friendly experience.</p><ul><li><strong>Gentle: </strong>N-EVAP nitrogen evaporators combine nitrogen blow down with a heated bath to gently concentrate delicate samples</li><li><strong>Flexible: </strong>An adjustable sample holder design fits a wide variety of sample tubes and vials at once</li><li><strong>Customizable: </strong>A large sample holder option can be added to accommodate vials with a larger outside diameter up to 70 mm</li><li><strong>Individualized Control: </strong>Optimize evaporation of diverse samples with individual gas flow control at each vial</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_24_Position_N_EVAP_Nitrogen_Evaporator_2_18a854b63f.jpg" alt="Organomation 24 Position N-EVAP Nitrogen Evaporator ." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_24_Position_N_EVAP_Nitrogen_Evaporator_2_18a854b63f.jpg 156w," sizes="100vw" width="1400" height="1400"></p><h3><strong>STANDARD FEATURES</strong></h3><ul><li>Nitrogen filter</li><li>Adjustable flow meter, 0-20 LPM</li><li>High pressure phthalate free tubing for safety</li><li>High temperature limit switch for safety</li><li>Dual band spring hoist assembly (except in dry bath model)</li><li>Precision needle valve tube assembly</li><li>Needles, 4 inch x 19 gauge with chrome plated brass hub and stainless steel shaft</li></ul><h3><strong>OPTIONS&nbsp;</strong></h3><ul><li>220v wiring harness (Option Code# -2), Cat# 11250-2</li><li>Z-Purge/positive pressure purge case (Option Code# -Z), Cat# 11250-Z</li><li>Acid resistant coating on instrument and needles (Option Code# -RT), Cat# 11250-RT</li><li>Side control box with built-in digital controller, timer, and pressure regulator (Option Code -CB), Cat# 11250-CB</li></ul><h3><strong>SPECS</strong></h3><h4><strong>24 Position N-EVAP (Water Bath)</strong></h4><ul><li><strong>Bath Type</strong>: Water</li><li><strong>Instrumental Catalog Number</strong>: 11250</li><li><strong>Number of Sample Positions</strong>: 24</li><li><strong>Overall Dimension (w × d × h)</strong>: 16 × 15 × 33 in / 41 × 38 × 84 cm</li><li><strong>Sample Holder Layout</strong>: Circular</li><li><strong>Gas Manifold Layout</strong>: Single Ring</li><li><strong>Test Tube Range (Standard Sample Holder)</strong>: 10–30 mm OD</li><li><strong>Test Tube Range (Optional Sample Holder)</strong>: 30–70 mm OD</li><li><strong>Gas Flow Meter</strong>: 0–20 L/min</li><li><strong>Stainless Steel Needles (Length × Gauge)</strong>: 4.0 in × 19 ga / 102 mm × 19 ga</li><li><strong>Sample Tray Lift Mechanism</strong>: Dual Band Spring Hoist Assembly</li><li><strong>Rotating, Leak Tight Gas Fitting</strong>: Standard</li><li><strong>Standard Gas Input Range</strong>: 20–30 psig</li><li><strong>Gas Input Range with Optional Pressure Reducing Regulator</strong>: 30–160 psig</li><li><strong>Acid Resistant Coating</strong>: Optional</li></ul><h5><strong>Heating Device Specs</strong></h5><ul><li><strong>Model Number</strong>: 9125</li><li><strong>Heating Medium</strong>: Water</li><li><strong>Inside Dimensions (Diameter × Depth)</strong>: 12.0 × 4.5 in / 30.5 × 11.4 cm</li><li><strong>Outside Dimensions (w × d × h)</strong>: 16 × 15 × 7 in / 41 × 38 × 18 cm</li><li><strong>Total Wattage</strong>: 900 W</li><li><strong>Bath Temperature Range</strong>: 30–90 °C</li><li><strong>Temperature Controller Type</strong>: Mechanical Thermostat</li><li><strong>Controller Accuracy</strong>: ±2 °C</li></ul><h4><strong>24 Position N-EVAP (Dry Bath)</strong></h4><ul><li><strong>Bath Type</strong>: Dry</li><li><strong>Instrumental Catalog Number</strong>: 11250-DA</li><li><strong>Number of Sample Positions</strong>: 24</li><li><strong>Overall Dimension (w × d × h)</strong>: 16 × 15 × 27.5 in / 41 × 38 × 70 cm</li><li><strong>Sample Holder Layout</strong>: Circular</li><li><strong>Gas Manifold Layout</strong>: Single Ring</li><li><strong>Test Tube Range (Standard Sample Holder)</strong>: 10–30 mm OD</li><li><strong>Test Tube Range (Optional Sample Holder)</strong>: 30–70 mm OD</li><li><strong>Gas Flow Meter</strong>: 0–20 L/min</li><li><strong>Stainless Steel Needles (Length × Gauge)</strong>: 4.0 in × 19 ga / 102 mm × 19 ga</li><li><strong>Sample Tray Lift Mechanism</strong>: None/Fixed</li><li><strong>Rotating, Leak Tight Gas Fitting</strong>: N/A</li><li><strong>Standard Gas Input Range</strong>: 20–30 psig</li><li><strong>Gas Input Range with Optional Pressure Reducing Regulator</strong>: 30–160 psig</li><li><strong>Acid Resistant Coating</strong>: Optional</li></ul><h5><strong>Heating Device Specs</strong></h5><ul><li><strong>Model Number</strong>: 5125</li><li><strong>Heating Medium</strong>: Aluminum Beads (Glass Beads in RT Models)</li><li><strong>Inside Dimensions (Diameter × Depth)</strong>: 12.0 × 4.5 in / 30.5 × 11.4 cm</li><li><strong>Outside Dimensions (w × d × h)</strong>: 16 × 15 × 7 in / 41 × 38 × 18 cm</li><li><strong>Total Wattage</strong>: 540 W</li><li><strong>Bath Temperature Range</strong>: 40–130 °C</li><li><strong>Temperature Controller Type</strong>: Mechanical Thermostat</li><li><strong>Controller Accuracy</strong>: ±2 °C</li></ul><h4><strong>24 Position N-EVAP (No Bath)</strong></h4><ul><li><strong>Bath Type</strong>: None</li><li><strong>Instrumental Catalog Number</strong>: 11250-O</li><li><strong>Number of Sample Positions</strong>: 24</li><li><strong>Overall Dimension (w × d × h)</strong>: 16 × 15 × 31.75 in / 41 × 38 × 81 cm</li><li><strong>Sample Holder Layout</strong>: Circular</li><li><strong>Gas Manifold Layout</strong>: Single Ring</li><li><strong>Test Tube Range (Standard Sample Holder)</strong>: 10–30 mm OD</li><li><strong>Test Tube Range (Optional Sample Holder)</strong>: 30–70 mm OD</li><li><strong>Gas Flow Meter</strong>: 0–20 L/min</li><li><strong>Stainless Steel Needles (Length × Gauge)</strong>: 4.0 in × 19 ga / 102 mm × 19 ga</li><li><strong>Sample Tray Lift Mechanism</strong>: Dual Band Spring Hoist Assembly</li><li><strong>Rotating, Leak Tight Gas Fitting</strong>: Standard</li><li><strong>Standard Gas Input Range</strong>: 20–30 psig</li><li><strong>Gas Input Range with Optional Pressure Reducing Regulator</strong>: 30–160 psig</li><li><strong>Acid Resistant Coating</strong>: Optional</li></ul><h3><strong>MODELS</strong></h3><h5><strong>Catalog Number &nbsp;/&nbsp;&nbsp;&nbsp;Bath Type</strong></h5><ul><li>11250: <strong>Water Bath</strong></li><li>11250-NT: <strong>No Teflon, Water Bath*</strong></li><li>11250-DA: <strong>Dry Bath</strong></li><li>11250-O: <strong>No Bath**</strong></li></ul><p><strong>*</strong> No Teflon (-NT) units designed for PFAS analysis using EPA methods 533, 537 and 537.1.<br><strong>**</strong>All “-O” models come with a base and stand assembly instead of a heated bath. These instruments are designed for evaporation procedures performed at ambient temperature.</p><h3><strong>ACCESSORIES</strong></h3><ul><li>Large vessel sample holder, 8 positions, for vial outside diameters of 30-70 mm (cat# NA1228)</li><li>Nitrogen generator (cat# NA1955)</li><li>Pasteur pipette adapters (cat# NA0636)</li><li>Pressure reducing regulator 0-160 psi (cat# NA0630)</li><li>High temperature silicone fluid (cat# NA1240)</li><li>Various needle sizes and gauges</li></ul><h3><strong>REPLACEMENT PARTS</strong></h3><ul><li>P0627: <strong>Valve Tube Assembly</strong> – Post 1997</li><li>P0607:<strong> Luer &amp; washer for N-EVAP valve tube</strong></li><li>P0634: <strong>Tube Fitting nylon 3 part for N-EVAP valve tube</strong></li></ul>

Organomation 34 Position N-EVAP Nitrogen Evaporator

Our 34-position nitrogen evaporator (cat# 11634) offers a large number of sample positions, without compromising any of the classic N-EVAP features. 

<p><strong>Our 34-position nitrogen evaporator (cat# 11634) offers a large number of sample positions, without compromising any of the classic N-EVAP features. This time-tested, durable system provides one of the least expensive prices per position of all our N-EVAPs. The evaporative system, along with the standard flow control and pressure reducing regulator, enables the operator to achieve the desired level of concentration with efficient nitrogen usage. Our unique dual band spring hoist assembly ensures easy and effective operator use.</strong></p><p>Additionally, the 34 position N-EVAP includes a side control box, which provides timed and digitally controlled water bath temperatures to produce even evaporation rates. The pressure regulator and timer combine to allow timed automatic gas flow cut off which slows evaporation to a minimum once the timed cycle has been completed. In order to prevent damage to delicate samples, the timer also provides the option for the heat to shut off once the cycle is complete.</p><ul><li><strong>Gentle: </strong>N-EVAP nitrogen evaporators combine nitrogen blow down with a heated bath to gently concentrate delicate samples</li><li><strong>Flexible: </strong>An adjustable sample holder design fits a wide variety of sample tubes and vials at once</li><li><strong>Precise: </strong>Digital controls allow exact temperature regulation</li><li><strong>Individualized Control: </strong>Optimize evaporation of diverse samples with individual gas flow control at each vial</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_34_Position_N_EVAP_Nitrogen_Evaporator_3_04176ee4e2.jpg" alt="Organomation 34 Position N-EVAP Nitrogen Evaporator." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_34_Position_N_EVAP_Nitrogen_Evaporator_3_04176ee4e2.jpg 156w," sizes="100vw" width="1400" height="1400"></p><h3><strong>STANDARD FEATURES</strong></h3><ul><li>Nitrogen filter</li><li>Adjustable flow meter, 0-30 LPM</li><li>Built-in pressure reducing regulator</li><li>Side control box</li><li>Digital temperature controller</li><li>Electronic timer</li><li>Safety control cover plate</li><li>High pressure phthalate free tubing&nbsp;</li><li>High temperature limit switch for safety</li><li>Dual band spring hoist assembly&nbsp;</li><li>Precision needle valve tube assembly</li><li>Needles, 4 inch x 19 gauge with chrome plated brass hub and stainless steel shaft</li></ul><h3><strong>OPTIONS&nbsp;</strong></h3><ul><li>220v wiring harness (Option Code# -2), Cat# 111634-2</li><li>Z-Purge/positive pressure purge case (Option Code# -Z), Cat# 11634-Z</li><li>Acid resistant coating on instrument and needles (Option Code# -RT), Cat# 11634-RT</li></ul><h3><strong>SPECS</strong></h3><h4><strong>34 Position N-EVAP (Water Bath)</strong></h4><ul><li><strong>Bath Type</strong>: Water</li><li><strong>Instrumental Catalog Number</strong>: 11634</li><li><strong>Number of Sample Positions</strong>: 34</li><li><strong>Overall Dimension (w × d × h)</strong>: 24 × 19 × 34 in / 61 × 48 × 86 cm</li><li><strong>Sample Holder Layout</strong>: Circular</li><li><strong>Gas Manifold Layout</strong>: Single Ring</li><li><strong>Test Tube Range (Standard Sample Holder)</strong>: 10–30 mm OD</li><li><strong>Gas Flow Meter</strong>: 0–30 L/min</li><li><strong>Stainless Steel Needles (Length × Gauge)</strong>: 4.0 in × 19 ga / 102 mm × 19 ga</li><li><strong>Built-in Nitrogen Gauge Input</strong>: 30–110 psig</li><li><strong>Sample Tray Lift Mechanism</strong>: Dual Band Spring Hoist Assembly</li><li><strong>Rotating, Leak Tight Gas Fitting</strong>: Standard</li><li><strong>Acid Resistant Coating</strong>: Optional</li></ul><h5><strong>Heating Device Specs</strong></h5><ul><li><strong>Model Number</strong>: 13165</li><li><strong>Heating Medium</strong>: Water</li><li><strong>Inside Dimensions (Diameter × Depth)</strong>: 16.0 × 4.5 in / 40.6 × 11.4 cm</li><li><strong>Outside Dimensions (w × d × h)</strong>: 24 × 19 × 6 in / 61 × 48 × 15 cm</li><li><strong>Total Wattage</strong>: 1300 W</li><li><strong>Bath Temperature Range</strong>: 30–90 °C</li><li><strong>Temperature Controller Type</strong>: Digital Electronic with LED Display</li><li><strong>Controller Accuracy</strong>: ±2 °C</li><li><strong>Side Mounted Control Box with Timer for Nitrogen &amp; Heat</strong>: Standard</li></ul><h4><strong>34 Position N-EVAP (No Bath)</strong></h4><ul><li><strong>Bath Type</strong>: None</li><li><strong>Instrumental Catalog Number</strong>: 11634-O</li><li><strong>Number of Sample Positions</strong>: 34</li><li><strong>Overall Dimension (w × d × h)</strong>: 19 × 17 × 32 in / 48 × 43 × 81 cm</li><li><strong>Sample Holder Layout</strong>: Circular</li><li><strong>Gas Manifold Layout</strong>: Single Ring</li><li><strong>Test Tube Range (Standard Sample Holder)</strong>: 10–30 mm OD</li><li><strong>Gas Flow Meter</strong>: 0–30 L/min</li><li><strong>Stainless Steel Needles (Length × Gauge)</strong>: 4.0 in × 19 ga / 102 mm × 19 ga</li><li><strong>Built-in Nitrogen Gauge Input</strong>: 30–110 psig</li><li><strong>Sample Tray Lift Mechanism</strong>: Dual Band Spring Hoist Assembly</li><li><strong>Rotating, Leak Tight Gas Fitting</strong>: Standard</li><li><strong>Acid Resistant Coating</strong>: Optional</li></ul><h3><strong>MODELS</strong></h3><h5><strong>Catalog Number &nbsp;/&nbsp;&nbsp;&nbsp;Bath Type</strong></h5><ul><li>11634: <strong>Water</strong></li><li>11634-O: <strong>No Bath*</strong></li></ul><p><strong>*</strong>All “-O” models come with a base and stand assembly instead of a heated bath. These instruments are designed for evaporation procedures performed at ambient temperature.</p><h3><strong>ACCESSORIES</strong></h3><ul><li>Nitrogen generator (cat# NA1955)</li><li>Pasteur pipette adapters (cat# NA0636)</li><li>High temperature silicone fluid (cat# NA1240)</li><li>Various needle sizes and gauges</li></ul><h3><strong>REPLACEMENT PARTS</strong></h3><ul><li>P0627: <strong>Valve Tube Assembly</strong> – Post 1997</li><li>P0607:<strong> Luer &amp; washer for N-EVAP valve tube</strong></li><li>P0634: <strong>Tube Fitting nylon 3 part for N-EVAP valve tube</strong></li></ul>

Organomation 45 Position N-EVAP Nitrogen Evaporator

Our 45-position nitrogen evaporator offers the largest number of sample positions in our N-EVAP line. 

<p><strong>Our 45-position nitrogen evaporator (Catalog # 11645) offers the largest number of sample positions in our N-EVAP line. The sample holder has dual circular rings. The outer ring has 30 positions and can accommodate samples with an outside diameter of 10-19 mm The inner ring has 15 positions and can accommodate samples with an outside diameter of 16-30 mm and a minimum height of 70 mm.</strong></p><p>This time-tested, durable system provides the least expensive price per position of all our N-EVAPs. The evaporative system, along with the standard flow control and pressure reducing regulator, enables the operator to achieve the desired level of concentration with efficient nitrogen usage. Our unique dual band spring hoist assembly ensures easy and effective operator use. Additionally, the 45 position N-EVAP includes a side control box. Timed, digitally controlled water bath temperatures provide even evaporation rates. The pressure regulator and timer combine to allow timed automatic gas flow cut off which slows evaporation to a minimum once the timed cycle has been completed. The heat can also be shut off with the gas after a timed cycle.</p><ul><li><strong>Gentle: </strong>N-EVAP nitrogen evaporators combine nitrogen blow down with a heated bath to gently concentrate delicate samples</li><li><strong>Flexible: </strong>An adjustable sample holder design fits a wide variety of sample tubes and vials at once</li><li><strong>Precise: </strong>Digital controls allow exact temperature regulation</li><li><strong>Individualized Control: </strong>Optimize evaporation of diverse samples with individual gas flow control at each vial</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_45_Position_N_EVAP_Nitrogen_Evaporator_5_20078e3969.jpg" alt="Organomation: 45 Position N-EVAP Nitrogen Evaporator." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_45_Position_N_EVAP_Nitrogen_Evaporator_5_20078e3969.jpg 156w," sizes="100vw" width="1400" height="1400"></p><h3><strong>STANDARD FEATURES</strong></h3><ul><li>Nitrogen filter</li><li>Adjustable flow meter, 0-30 LPM</li><li>Built-in pressure reducing regulator</li><li>Side control box</li><li>Digital temperature controller</li><li>Electronic timer</li><li>Safety control cover plate</li><li>High pressure phthalate free tubing&nbsp;</li><li>High temperature limit switch for safety</li><li>Dual band spring hoist assembly&nbsp;</li><li>Precision needle valve tube assembly</li><li>Needles, 4 inch x 19 gauge with chrome plated brass hub and stainless steel shaft</li></ul><h3><strong>OPTIONS&nbsp;</strong></h3><ul><li>220v wiring harness (Option Code# -2), Cat# 11645-2</li><li>Z-Purge/positive pressure purge case (Option Code# -Z), Cat# 11645-Z</li><li>Acid resistant coating on instrument and needles (Option Code# -RT), Cat# 11645-RT</li></ul><h3><strong>SPECS</strong></h3><h4><strong>45 Position N-EVAP (Water Bath)</strong></h4><ul><li><strong>Bath Type</strong>: Water</li><li><strong>Instrumental Catalog Number</strong>: 11645</li><li><strong>Number of Sample Positions</strong>: 45</li><li><strong>Overall Dimension (w × d × h)</strong>: 24 × 19 × 34 in / 61 × 48 × 86 cm</li><li><strong>Sample Holder Layout</strong>: Circular</li><li><strong>Gas Manifold Layout</strong>: Dual Rings</li><li><strong>Outer Circle Sample Holder Test Tube Range</strong>: 10–19 mm OD</li><li><strong>Inner Circle Sample Holder Test Tube Range</strong>: 16–30 mm OD; &gt;70 mm height</li><li><strong>Gas Flow Meter</strong>: 0–30 L/min</li><li><strong>Stainless Steel Needles (Length × Gauge)</strong>: 4.0 in × 19 ga / 102 mm × 19 ga</li><li><strong>Sample Tray Lift Mechanism</strong>: Dual Band Spring Hoist Assembly</li><li><strong>Rotating, Leak Tight Gas Fitting</strong>: Standard</li><li><strong>Built-in Nitrogen Gauge Input</strong>: 30–110 psig</li><li><strong>Acid Resistant Coating</strong>: Optional</li></ul><h5><strong>Heating Device Specs</strong></h5><ul><li><strong>Model Number</strong>: 13165</li><li><strong>Heating Medium</strong>: Water</li><li><strong>Inside Dimensions (Diameter × Depth)</strong>: 16.0 × 4.5 in / 40.6 × 11.4 cm</li><li><strong>Outside Dimensions (w × d × h)</strong>: 24 × 19 × 6 in / 61 × 48 × 15 cm</li><li><strong>Total Wattage</strong>: 1300 W</li><li><strong>Bath Temperature Range</strong>: 30–90 °C</li><li><strong>Temperature Controller Type</strong>: Digital Electronic with LED Display</li><li><strong>Controller Accuracy</strong>: ±2 °C</li><li><strong>Side Mount Control Box with Timer for Nitrogen &amp; Heat</strong>: Standard</li></ul><h4><strong>45 Position N-EVAP (No Bath)</strong></h4><ul><li><strong>Bath Type</strong>: None</li><li><strong>Instrumental Catalog Number</strong>: 11645-O</li><li><strong>Number of Sample Positions</strong>: 45</li><li><strong>Overall Dimension (w × d × h)</strong>: 24 × 19 × 32 in / 61 × 48 × 81 cm</li><li><strong>Sample Holder Layout</strong>: Circular</li><li><strong>Gas Manifold Layout</strong>: Dual Rings</li><li><strong>Outer Circle Sample Holder Test Tube Range</strong>: 10–19 mm OD</li><li><strong>Inner Circle Sample Holder Test Tube Range</strong>: 16–30 mm OD; 70 mm height</li><li><strong>Gas Flow Meter</strong>: 0–30 L/min</li><li><strong>Stainless Steel Needles (Length × Gauge)</strong>: 4.0 in × 19 ga / 102 mm × 19 ga</li><li><strong>Sample Tray Lift Mechanism</strong>: Dual Band Spring Hoist Assembly</li><li><strong>Rotating, Leak Tight Gas Fitting</strong>: Standard</li><li><strong>Built-in Nitrogen Gauge Input</strong>: 30–110 psig</li><li><strong>Acid Resistant Coating</strong>: Optional</li></ul><h3><strong>MODELS</strong></h3><h5><strong>Catalog Number &nbsp;/&nbsp;&nbsp;&nbsp;Bath Type</strong></h5><ul><li>11645: <strong>Water Bath</strong></li><li>11634-O: <strong>No Bath*</strong></li></ul><p><strong>*</strong>All “-O” models come with a base and stand assembly instead of a heated bath. These instruments are designed for evaporation procedures performed at ambient temperature.</p><h3><strong>ACCESSORIES</strong></h3><ul><li>Nitrogen generator (cat# NA1955)</li><li>Pasteur pipette adapters (cat# NA0636)</li><li>High temperature silicone fluid (cat# NA1240)</li><li>Various needle sizes and gauges</li></ul><h3><strong>REPLACEMENT PARTS</strong></h3><ul><li>P0627: <strong>Valve Tube Assembly</strong> – Post 1997</li><li>P0607:<strong> Luer &amp; washer for N-EVAP valve tube</strong></li><li>P0634: <strong>Tube Fitting nylon 3 part for N-EVAP valve tube</strong></li></ul>

Products focused on Sample Preparation - page 5

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