Thermo Scientific™ EASY-Spray™ Sources are integrated nano-electrospray ion sources designed for nanoflow LC-MS. Their temperature-controlled column-emitter assembly and single nanoViper™ connection simplify nanoLC-MS operation while delivering highly reproducible separations, stable spray performance, and high LC-MS sensitivity
Integrated Design
- Integrated temperature-controlled column and emitter assembly
- Single nanoViper™ connection between the LC system and ion source
- Integrated zero-dead-volume (ZDV) connections minimize dead volume
- Simple plug-and-spray installation with quick column replacement
Chromatographic Performance
- Stable nano-electrospray ionization for reliable LC-MS analysis
- Supports long columns and small particle sizes for high peak-capacity separations
- Column heating (30–60 °C) reduces solvent viscosity and backpressure
- Ultra-sharp chromatographic peaks improve separation efficiency
Thermo Scientific EASY-Spray Sources: The entire assembly is designed for heavy use so you can utilize the full pressure range of your UHPLC front-end (up to 1000 bar) and benefit from small particles and long columns. Longer columns and longer gradients both contribute to more identifications.
Reproducibility
- Stable performance during extended analytical operation
- Excellent run-to-run reproducibility
- Outstanding column-to-column reproducibility for large studies and multi-site laboratories
Ease of Use
- Plug-and-spray operation requiring minimal setup
- Integrated camera provides an illuminated, magnified view of the emitter tip
- Eliminates the most error-prone nanoLC connections
Compatibility
Compatible with Thermo Scientific EASY-Spray columns and selected Thermo Scientific nanoLC systems and mass spectrometers, including:
- Thermo Scientific™ LCQ Deca XP MAX™, LTQ™-series, and Velos™ series ion trap mass spectrometers
- Thermo Scientific™ LTQ Orbitrap™-series and Orbitrap Velos™ series hybrid ion trap-Orbitrap mass spectrometers
- Thermo Scientific™ Exactive™ series Orbitrap mass spectrometers
- Thermo Scientific™ Q Exactive™ series hybrid quadrupole-Orbitrap mass spectrometers
- Thermo Scientific™ TSQ Quantum™ series and TSQ Vantage™ triple-stage quadrupole mass spectrometers
The EASY-Spray NG ion source works in conjunction with the latest next-generation Thermo Scientific mass spectrometers:
- Thermo Scientific™ Orbitrap™ Fusion™ Tribrid™ Mass Spectrometer
- Thermo Scientific™ TSQ Endura™ Triple-stage Quadrupole Mass Spectrometer
- Thermo Scientific™ TSQ Quantiva™ Triple-stage Quadrupole Mass Spectrometer
