The KNAUER AZURA® AS 6.1L is a high-performance autosampler designed for automated sample injection in HPLC/UHPLC systems, offering high capacity, precision, and flexibility for both routine and high-throughput applications.
The autosampler supports:
- up to 768 sample positions (microtiter plates)
- up to 108 standard 1.5 mL vials
A highly effective internal and external needle wash system minimizes carryover to extremely low levels. The system is also fast, with a complete injection cycle taking less than one minute, including needle washing.
Three injection modes are supported:
- full loop filling (highest precision)
- partial loop filling (variable volumes)
- µl pickup (loss-free injection of small volumes)
The integrated ILD™ (Intermediate Loop Decompression) valve ensures accurate high-pressure injections without sample dilution and reduces pressure spikes, protecting the column.
Key Features
- Autosampler for HPLC/UHPLC systems
- Up to 768 sample positions
- Up to 108 vials (1.5 mL)
- Ultra-low carryover (< 0.0003%)
- Fast injection cycle (< 1 min)
- 3 injection modes (full loop, partial loop, µl pickup)
- ILD™ technology for high-pressure injection
- PASA™ (pressure-assisted sample aspiration)
- Optional sample cooling (4–40 °C)
- Missing vial/plate detection
- Supports precolumn derivatization
Technical Specifications
Sample Injection
- Injection volume range: 0.1 µl – 10 mL
- Precision:
- Full loop: < 0.3% RSD
- Partial loop: < 0.5% RSD
- µl pickup: < 1.0% RSD
- Accuracy: 0.2 µl (250 µl syringe)
Performance
- Carryover:
- < 0.0015% (standard)
- < 0.0003% (extended wash)
- Injections per vial: max. 9
- Cycle time:
- 7 s (same vial)
- 14 s (different vials)
- < 60 s total
Capacity & Compatibility
- Microtiter plates: ANSI SLAS standard
- Max vial/plate height: 47 mm
Additional Features
- Headspace pressure (bubble prevention)
- Precolumn derivatization
- Sample tray cooling (optional, 4–40 °C)
- Vial detection sensor
Materials
- ETFE, PTFE, stainless steel, glass, Vespel
- Wide chemical compatibility
Control & Communication
- LAN / Ethernet
- Analog inputs
- TTL inputs (start, stop, freeze)
- Relay output (alarm, marker)
Operating Conditions
- Temperature: 10–40 °C
- Humidity: 20–80%
