Bringing high-resolution Orbitrap technology into routine GC-MS workflows
The Exactive GC Orbitrap system offers the unmatched mass accuracy, resolving power, and sensitivity of Orbitrap technology in a platform optimized for routine applications. This high-performance GC-MS system enables both targeted and non-targeted full-scan workflows with confident quantitation and trace-level detection, even in complex matrices. Designed for maximum robustness and usability, it streamlines operations across food safety, environmental, industrial, forensic, and anti-doping laboratories.
Key Features and Benefits
💡 Unmatched HRAM Performance
- Resolving power up to 60,000 FWHM at m/z 200
- Mass accuracy: <1 ppm (internal), <3 ppm (external)
- Quantitative dynamic range: >10⁶, with excellent linearity and precision
- Routine IDLs in the sub-ppb to ppt range
🧪 Full-Scan Sensitivity and Selectivity
- Combines triple-quad-like quantitation with full-scan Orbitrap capability
- Sub-ppb sensitivity for 100+ pesticides in food matrices
- High selectivity and confidence in trace-level compound identification
- Spectral deconvolution with accurate-mass fragment filtering
⚙️ Proven Orbitrap Design
- Curved linear trap (C-Trap) and bent flatapole ion optics
- ExtractaBrite™ ion source (EI/PCI/NCI) – removable under vacuum
- Vent-free column exchange using patented source plug
- Optional direct sample probes (DIP, DEP) for solid or thermolabile analytes
🧠 Streamlined Software and Data Processing
- Controlled by TraceFinder™ and Xcalibur™ platforms
- Full-scan acquisition with automated data mining
- Integrated spectral libraries (NIST, Thermo Food/Environmental)
- Spectral fidelity and mass accuracy retained across wide concentration range
🔁 Optimized GC Integration
- Built on the TRACE™ 1310 GC platform
- Supports all injection/detection configurations (SSL, PTV, backflush, etc.)
- Paired with TriPlus™ RSH autosampler for advanced robotic sample handling
- Excellent retention time stability and fast oven cycling
Ideal For Applications In:
- Food safety and authenticity (pesticide screening, additives)
- Environmental analysis (contaminants, pollutants, air toxics)
- Forensics and toxicology (unknowns, drugs, metabolites)
- Industrial QC (extractables, volatiles, impurity profiling)
- Non-targeted screening with full-scan HRAM and retrospective analysis
Thermo Scientific™ Exactive™ GC Orbitrap™ GC-MS System
