Static headspace enantioselective comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry in food analysis: a proof-of-principle study

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 13th July 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you posters by <strong>Agilent Technologies / ASMS,&nbsp;</strong> <strong>MDCW / William &amp; Mary, </strong>and<strong> Thermo Fisher Scientific</strong> <strong>/ ASMS </strong>and technical note by <strong>Shimadzu!</strong></p><h3><strong>1. Agilent Technologies / ASMS: Comprehensive PFAS Analysis in Textiles Using Triple Quadrupole GC/MS and LC/MS Workflows</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_pfas_textiles_gc_tq_lc_tq_wp_414_asms_2026_en_agilent_a1d50ab96c.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>Per- and polyfluoroalkyl substances (PFAS) are widely used in textiles to provide water-, stain-, and oil-repellent functionality. Increasing evidence of environmental and human-health risks has led to heightened global regulatory pressure, including REACH/POPs restrictions, and strengthened requirements from industry frameworks such as ZDHC, OEKO-TEX®, AFIRM, and Bluesign. These initiatives demand highly sensitive, reliable, and standardized analytical workflows capable of quantifying both volatile and non-volatile PFAS in diverse textile matrices. This study demonstrates end-to-end PFAS solutions aligned with EN 17681-1:2025, comprising heat- and ultrasound-assisted (HUA) extraction followed by GC/TQ and LC/TQ determination of volatile and non-volatile PFAS, respectively. The workflow enables robust quantification of a comprehensive PFAS panel in T-shirts, waterproof shorts, and socks.</p><h4><strong>Experimental</strong></h4><h5><strong>Instrumentation&nbsp;</strong></h5><p>A dual-platform analytical approach combining GC/TQ and LC/TQ systems was used to quantify over 100 PFAS across 14 chemical classes (Figure 1). More than 30 volatile PFAS were analyzed using an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890"><strong>Agilent 8890 GC</strong></a> coupled to a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7010D"><strong>7010D TQ</strong></a> and a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=DB-624"><strong>DB-624 column</strong></a>. Over 70 non-volatile PFAS were determined using an <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=10&amp;search=6475"><strong>Agilent 6475 LC/TQ</strong></a> paired with a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=10&amp;search=1290+infinity+III"><strong>1290 Infinity III UHPLC </strong></a>and a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library?mainauthorItems=10&amp;search=ZORBAX+RRHD+Eclipse+Plus+C18"><strong>ZORBAX RRHD Eclipse Plus C18</strong></a> column.</p><h4><strong>Conclusions</strong></h4><ul><li>A dual-platform approach deploys Agilent 8890 GC coupled with 7010D TQ and Agilent 1290 Infinity III LC with 6475A TQ system for volatile and non-volatile PFAS in textiles.&nbsp;</li><li>Fast and simplified workflow: Utilizes a streamlined protocol based on EN 17681-1:2025. The method enhances lab productivity by eliminating tedious evaporation and reconstitution steps.&nbsp;</li><li>Regulatory compliance: Effectively addresses increasing textile industry focus on PFAS monitoring and supports compliance with various regulatory standards and limit requirements for PFAS detection in textiles.</li></ul><h3><strong>2. MDCW / William &amp; Mary: The Effect Of Using Low-Bleed Columns In The First Dimension For Comprehensive Two-Dimensional Gas Chromatographic Analyses</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/Webb_MDCW_Poster_2026_1_5657991949.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>In gas chromatography, the presence of column bleed impacts peak data quality. As siloxanebased stationary phase components fragment, they release bleed artifacts into the mass spectrometer (MS), producing interference and decreasing signal-to-noise ratios (S/N) of analytes. <sup>1</sup> When using comprehensive twodimensional gas chromatography (GC×GC), a secondary column with an orthogonal stationary phase is used in providing improved separation between column bleed and analytes. However, it also introduces more stationary phase that can be degraded to produce more bleed artifacts.</p><p>The goal of this research was to define how replacing the primary column in a GC×GC-MS system impacts the resulting S/N and analyte identification quality, in order to clarify how column bleed impacts analytes that appear to be chromatographically resolved from column artifacts in GC×GC output. This will demonstrate the advantage that low-bleed columns can provide for future analyses.</p><h5><strong>Methods</strong></h5><p>Samples analyzed were the Century Mix2 , containing approximately 100 different analytes within different classes (i.e. Century Mix2) and a 52- component Indoor Air Standard. Both were assessed using a 5% phenyl/95% dimethylsiloxane standard column in the first dimension and a (50%-phenyl)-methylpolysiloxane standard column in the second dimension. Samples were then reanalyzed with a low-bleed column replacement in the first dimension.</p><p>Analysis of the samples was performed using the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/37"><strong>Pegasus BT4D GC×GCTOFMS</strong></a> with a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/44"><strong>quad-jet dual-stage cryogenic modulator</strong></a><strong> </strong>(LECO Corporation). <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/41"><strong>ChromaTOF software</strong></a><strong> </strong>(LECO Corporation) was used to analyze the chromatographic data.</p><h4><strong>Conclusions</strong></h4><p>This work demonstrated that samples run with the low-bleed first dimension column showed a reduction in the presence of column bleed components identified and maintained or improved the quantitative signal-to-noise ratios of components compared to the samples run on standard first dimension columns. This showed that that low concentration analytes were more reliably detected in the absence of column bleed, even when contour plots showed physically resolved components. In the future, this can be applied to improve the resolution of complex samples and increase analyte signal.</p><h3><strong>3. Shimadzu: Dimethyl carbonate as a green organic modifier in supercritical fluid extraction of pesticide residue analysis in apple samples</strong></h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c190_e347_869b9e2ade.pdf"><strong>Full PDF for download</strong></a></li></ul><p>According to the Green Analytical Chemistry (GAC) principles[1], a highly promising strategy to minimize the side effects of analytical methods involves replacing potentially toxic solvents and/or obtained by non-renewable sources with more environmentally friendly alternatives. In this frame, dimethyl carbonate (DMC) is an environmentally friendly, non-corrosive, safe handling, and biodegradable chemical, extensively used in several application fields, such as pharmaceuticals, coatings, and lithium-ion battery electrolytes [2]. Additionally, instead of the historical use of toxic and corrosive phosgene as a carbonate source, simple and direct synthesis routes from carbon dioxide (CO2) have been proposed [3]. Thus, also falling within the “carbon capture and utilization” processes, ensuring the reduction of atmospheric CO2 concentration and its conversion into useful chemical products.&nbsp;</p><p>Firstly introduced in the second edition of the GlaxoSmithKline’s solvent selection guide, DMC has been included among the “few issues” solvents, along with water [4]. Thereafter, it has attracted widespread attention as a valuable chemical and/or solvent, and substantial research efforts have been made in the scientific community. Its potential as a green alternative to conventional solvents in both reversed-phase liquid chromatography [5–7] and supercritical fluid chromatography [8] has been explored. The extraction capabilities of DMC toward different target molecules have been also investigated. In 2022, Alfieri et al. optimized an ultrasoundassisted extraction of two lignans from Linum species [9]. The extraction performances of a panel of green solvents and two natural deep eutectic solvents (in combination with water in a solvent/water ratio of 80:20) were tested versus methanol and chloroform (used for comparison with published studies). The results showed that, in terms of purity and recovery, DMC was the optimal media for the 6-methoxypodophyllotoxin extraction. DMC has been also employed in an in-syringe extraction coupled to solid phase extraction to assess nicotine in environmental water and sportspersons’ urine samples [10]. Extracts enriched in oleanolic acid were obtained by solid-liquid extraction of grape pomace using DMC compared to other tested solvents (ethyl acetate, acetone, n-butanol) [11]. In addition to the highest obtained recovery value, the lowest co-extraction of other matrix components was also achieved.&nbsp;</p><p>Supercritical fluid extraction (SFE) represents a reliable alternative to conventional solvent-based extraction methods. Several advantages are provided when CO2 is employed as supercritical fluid due to its non-toxicity, non-flammability, abundancy, renewability (as a by-product of industrial processes, as fermentation or combustion), recyclability, and cost-effectiveness. Supercritical CO2 has a polarity similar to that of n-hexane; thus, the addition of a co-solvent is necessary for the extraction of polar molecules [12, 13].&nbsp;</p><p>This work aims to expand the use of DMC that, to the best of the author’s knowledge, is here firstly proposed as an organic modifier in SFE. The extraction efficiency and selectivity of DMC toward conventional solvents, such as acetonitrile (ACN) and bio-ethanol (EtOH) obtained from edible renewable feedstocks, has been evaluated for multi-residue analysis of pesticides (64 pesticides, representing diverse chemical classes, polarities, and molecular weights) in apple samples. Considering the sustainable and nontoxic nature of CO2 and DMC, the use of DMC in SFE represents a win-win combination. Thus, improving the overall sustainability and automation of the extraction process closely align with the GAC principles. Furthermore, in this research, always following the GAC principles, a low-pressure gas chromatography-tandem mass spectrometry (LP-GC-QqQMS) method was employed, allowing a greater sample loadability and a higher optimal linear velocity allowed by the vacuum conditions of the system, effectively reducing the analysis time at about 10 minutes [14, 15].</p><h4><strong>2. Materials and methods</strong></h4><h5><strong>2-3. Instrumentation</strong></h5><h5><strong>Low‑pressure gas chromatography triple quadrupole mass spectrometry&nbsp;</strong></h5><p>The LP-GC-QqQMS analyses were performed using a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GC-2010"><strong>GC-2010 Plus system</strong></a> (Shimadzu Corporation, Kyoto, Japan) coupled with a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=8040"><strong>triple quadrupole mass spectrometer (TQ8040</strong></a>, Shimadzu). Injection was performed using an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=AOC-20i"><strong>AOC-20i autosampler</strong></a><strong> </strong>and<strong> </strong>a split/splitless injector (injection temperature 280 °C) equipped with a focus liner (volume: 810 μL). The injection was performed in splitless mode (3 μL) using the high-pressure injection mode function (290 kPa for 0.5 min).&nbsp;</p><p>To avoid that sub-ambient pressure conditions reach the injector, an uncoated column (0.48 m × 0.1 mm ID) was installed before the separation column, a non-polar Equity-5 [poly(5% diphenyl/95% dimethyl siloxane)] of the following dimension: 5 m × 0.53 mm ID × 0.53 μm df. Both the columns were provided by Merck KGaA. The oven was temperature programmed as follows: 40 °C (2 min) to 320 °C raised at 30 °C min−1. Helium was used as carrier gas with an average constant linear velocity of 100 cm s−1 (into the separation column).&nbsp;</p><p>Electron ionization was performed at 70 eV. The interface and ion source temperatures were 320 and 280 ˚C, respectively. The collision gas was argon at a pressure of 200 kPa. The targeted analyses were carried out in the multiple reaction monitoring (MRM) acquisition mode (acquisition frequency: 3.3 Hz). To ensure univocal identification, two different MRM transitions (quantifier and qualifier) were monitored for each compound (Table S1). The SCAN analysis was performed with an acquisition frequency of 3.3 Hz and a mass range of 50–600 m/z. The GCMS Solution v.4.45 software (Shimadzu) was used for data collection and processing.</p><h4><strong>4. Conclusions&nbsp;</strong></h4><p>Under the optimized extraction conditions, the use of DMC as a co-solvent in SFE demonstrated promising performance in the analysis of pesticide residues in apple samples. The method achieved an average extraction yield of 85% across the 64 analyzed pesticides, spanning a broad range of chemical classes, polarities, and molecular weights. Notably, DMC provided cleaner extracts with significantly lower amounts of co-extracted matrix components compared to conventional solvents like ACN and EtOH. Despite the recovery for certain analytes being below 70%, the results remained within acceptable precision limits according to SANTE guidelines. Overall, DMC not only fulfills the analytical requirements for pesticide residue determination but also offers a greener, more sustainable alternative that supports enhanced instrument maintenance and aligns with the principles of GAC.</p><h3><strong>4. Thermo Fisher Scientific / ASMS: Improved detection capabilities for polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs) using GC Orbitrap MS</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_004693_lsms_pcdd_fs_exploris_gc_efs_po004693_asms2026_na_en_68e4d9e8b3.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Polychlorinated dibenzo-p-dioxins/furans (PCDD/F) analysis requires ultra-high sensitivity and selectivity due to their toxicity at trace levels. Regulatory compliance requires laboratories to adhere to strict analytical criteria (Figure 1). Through the integration of NVAEI source (NVAEI) with HRAM Thermo Scientific Orbitrap mass spectrometer, the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/2419"><strong>Orbitrap Exploris GC S </strong></a>delivers mass resolution and accuracy that far exceed those required while delivering enhanced sensitivity required for pg/g (part per trillion (ppt)) detection within food and feed matrices.</p><h4><strong>Conclusions&nbsp;</strong></h4><p>Enhanced sensitivity of the NeverVent AEI ion source coupled to the Orbitrap Exploris GC S delivers accurate quantitation down to 2 fg/μL (10 fg on column) of TCDD while meeting analytical criteria required for Dioxin analysis compliance.&nbsp;</p><p>Response of 2 fg/μL (10 fg on column) of TCDD standard remained stable over a 185-injection sequence of food/feed extract, demonstrating robust performance of the NeverVent AEI at maintaining trace level sensitivity.&nbsp;</p><p>Good agreement in the analysis of food and feed extracts preformed by GC-HRMS magnetic sector demonstrates the Orbitrap Exploris GC S can deliver accurate quantitation at and below regulatory limits.</p></div></div></div></div></div></div></section></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 29, 2026

News from LabRulezGCMS Library - Week 39, 2026

<p><strong>Gas Chromatography–Mass Spectrometry (GC-MS) and Comprehensive Two-Dimensional Gas Chromatography (GCxGC) are the gold standards for analyzing complex organic mixtures. This dual capability eliminates analytical blind spots and provides a more complete chemical profile.</strong></p><ul><li>GC-MS provides molecular identification and high sensitivity for both target quantification and non-target screening.</li><li>GCxGC exponentially increases analyte separation, exposing trace components and simplifying group-type analyses.</li><li>Together, these technologies offer an unparalleled toolset for volatile and semi-volatile sample characterization.</li></ul><h3><strong>Achieving Identification with TOF Technology</strong></h3><p>Gas Chromatography–Mass Spectrometry (GC-MS) is a foundational analytical tool for volatile and semi-volatile characterization. By resolving analytes from complex mixtures in the gas phase, the system allows for&nbsp;critical&nbsp;detection and identification of individual components. While traditional scanning quadrupole systems are effective for routine target analysis, Time-of-Flight (TOF) mass spectrometers significantly enhance capabilities for discovery-based work and complex&nbsp;sample&nbsp;characterization.</p><ul><li><strong>Uncompromised Full-Range Sensitivity:</strong>&nbsp;Unlike scanning&nbsp;mass spectrometers&nbsp;that lose sensitivity as scan speed increases, TOF systems can collect full mass range data at full sensitivity. This enables femtogram-level&nbsp;detection&nbsp;even when&nbsp;acquiring&nbsp;non-target data, ensuring that trace-level&nbsp;analytes&nbsp;are not missed.&nbsp;</li><li><strong>High-Speed Acquisition &amp; Deconvolution:</strong> Modern TOF technology provides the high data acquisition rates required to support extremely narrow chromatographic peaks associated with fast GC and GCxGC. Software algorithms automatically deconvolute coeluting peaks, extracting clean spectra for individual components</li><li><strong>Reliable Molecular Fingerprinting:</strong>&nbsp;Mass spectrometry creates a unique spectral “fingerprint” for each&nbsp;molecule. TOFMS&nbsp;facilitates&nbsp;accurate&nbsp;matching against extensive libraries&nbsp;thanks to the absence of spectral skewing associated with scanning instruments, providing definitive identification of both known and unknown analytes.&nbsp;</li><li><strong>System Versatility:</strong>&nbsp;These platforms are highly configurable, supporting a variety of autosamplers, ionization sources (such as EI or CI), and chromatography accessories to satisfy a wide range of&nbsp;methodology&nbsp;requirements and complex sample types.&nbsp;</li></ul><h3><strong>Powerful Chromatographic Separation for Complex Samples</strong></h3><p>When samples are too complex for conventional single-dimensional analysis—such as crude oil, complex aromas, or environmental extracts—Comprehensive Two-Dimensional Gas Chromatography (GCxGC) is required. By continuously capturing segments of effluent from a primary column and reinjecting them into a secondary column with a different stationary phase, GCxGC can provide a nearly 10-fold increase leap in resolving power.</p><ul><li><strong>Maximize Identifications:</strong>&nbsp;GCxGC&amp; instruments identify significantly more analytes than traditional GC by providing the chromatographic resolution necessary to separate components from each other and the matrix.&nbsp;</li><li><strong>Structured Chromatograms:</strong>&nbsp;Analytes elute in predictable “classes” within the two-dimensional space (e.g., alkanes,&nbsp;aromatics, FAMEs). This creates a structured chemical map, simplifying group-type&nbsp;interpretation&nbsp;and the fingerprinting of complex chemistries.&nbsp;</li><li><strong>Discovery of Hidden Components:</strong>&nbsp;By resolving coelutions,&nbsp;GCxGC&nbsp;exposes trace compounds that are typically obscured by more abundant species, making it the premier tool for research, development, and high-level discovery work.&nbsp;</li></ul><h3><strong>Flexible Configurations and System Options</strong></h3><p>Analytical platforms for GC and GC-MS are highly configurable, allowing laboratories to tailor the hardware to their specific&nbsp;methodology.&nbsp;</p><ul><li><strong>Automated Sample Introduction:</strong>&nbsp;Systems can be equipped with various autosampler solutions&nbsp;for performing various injection types&nbsp;including liquid, headspace,&nbsp;solid phase&nbsp;microextraction (SPME),&nbsp;Pyrolysis, Thermal Desorption, and more&nbsp;to streamline workflows.&nbsp;</li><li><strong>Ionization Modes:</strong>&nbsp;Standard EI (electron impact) ionization can be complemented with CI (Chemical ionization) and NCI (Negative chemical ionization)&nbsp;to&nbsp;assist&nbsp;in both library matching and molecular weight confirmation.&nbsp;</li><li><strong>Modulation Techniques:</strong>&nbsp;Both thermal and flow-based modulation options exist for&nbsp;GCxGC, allowing for the optimization of separation based on analyte volatility, sensitivity needs, and&nbsp;laboratory infrastructure.&nbsp;</li></ul><h3><strong>Industry Value: Why Advanced Analytical Techniques Are Indispensable</strong></h3><p>GC and GC-MS serve as a cornerstone for quality, safety, and innovation across many critical industries. By delivering high-precision data, these methodologies enable professionals to navigate rigorous regulatory environments, optimize complex manufacturing processes, and accelerate research breakthroughs. Explore the industries below to learn more on how these analytical capabilities provide the essential insights required to maintain quality and drive operational success across these diverse sectors.</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.leco.com/application/petrochemicals/"><strong>Petrochemicals</strong></a><br>The chemical complexity of petroleum and derived products necessitates specific instrumentation for thorough characterization. LECO’s GCxGC and TOFMS instruments simplify the classification and comparison of petroleum products for process optimization.&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.leco.com/application/environmental/"><strong>Environmental</strong></a><br>Our suite of elemental analyzers and GC-MS platforms empowers labs to confidently identify trace-level compounds through unprecedented separation and rich spectral detail.&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.leco.com/application/food-safety/"><strong>Food Safety</strong></a><br>To help manufacturers meet strict regulatory and consumer standards for food safety, we offer advanced analytical equipment for contaminant detection.&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.leco.com/application/aroma-flavor-fragrance/"><strong>Flavor &amp; Fragrance</strong></a><br>Leveraging advanced GCxGC and TOFMS instruments, LECO empowers deeper aroma characterization, accurate reformulation, off-odor identification, and more.&nbsp;</li><li><strong>Pharmaceuticals</strong><br>Identification of unknown impurities and extractable/leachable compounds critical for drug safety.&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.leco.com/application/metabolomics/"><strong>Metabolomics</strong></a><br>Our advanced mass spectrometry instruments and innovative software tools are designed to help you decipher intricate metabolic disease pathways, explore new horizons in exposomics, and more.&nbsp;</li></ul><h3><strong>GC and GCxGC Instruments</strong></h3><p>The integration of GCxGC separations and Time-of-Flight mass spectrometry empowers researchers to see deeper into their samples. By combining high sensitivity with superior resolving power, these systems transform complex chemical mixtures into clear, actionable data for critical decision-making.</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1097"><strong>Pegasus BTX Series</strong></a><strong>: </strong>High-Sensitivity GC-TOFMS</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/products?category=22&amp;manufacturerItems=24&amp;search=hrt"><strong>Pegasus HRT Series</strong></a><strong>: </strong>Redefining High-Resolution Analysis&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/products?category=181&amp;manufacturerItems=24"><strong>GCxGC Modulation Solutions</strong></a><strong>:</strong> Solutions for Enhanced GCxGC Analysis&nbsp;</li></ul>

GC and GC-MS: Unmatched Separation, Sensitivity, and Identification

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In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

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4th European Sample Preparation Conference - 3rd Green and Sustainable Analytical Chemistry Conference (EuSP 2026 | GSAC 2026)

Thermo Fisher Scientific Mass Spectrometry Users’ Meetings 2026

Waters Corporation Advanced MS Day

Validated Method for PFAS Testing in Food, Including Meats

Confidence in PFAS Data: Smarter Sample Prep, Contamination Control, Highly Sensitive and Robust MS

From sample to result: advanced sample prep strategies for food and environmental matrices