Quantifiable consistency. By tracking retention time consistency and peak symmetry across years of production, column performance becomes directly comparable.In chromatography, inconsistent separations are inconvenient and costly.Every unexpected shift in retention time or change in peak shape can trigger a cascade of troubleshooting, reruns, and uncertainty that slows laboratory productivity.On the other hand, when columns perform consistently, laboratories recover valuable time, reduce uncertainty, and maintain confidence in their data. True batch-to-batch consistency means fewer failed validations, fewer investigations, easier audits, and smoother collaboration across global sites.In regulated industries, data integrity underpins every decision, from early development to final release testing, so consistent column performance is a necessity.<h3>Key takeaways</h3><ul><li>Batch-to-batch (U)HPLC column consistency directly influences long-term method performance by stabilizing retention times, preserving peak shape, and supporting reliable validation of pharmaceutical methods.</li><li>Multi-year performance data across thousands of columns shows us how controlled column manufacturing reduces chromatographic variability, supporting reproducible results across column formats, batches, and laboratories.</li><li>Stable (U)HPLC columns minimize revalidation, troubleshooting, and method transfer challenges in regulated workflows, improving analytical efficiency across the product lifecycle.</li></ul><h3>Defining and measuring batch-to-batch (U)HPLC column consistency</h3>A (U)HPLC column is packed with <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/chromatography/chromatography-learning-center/chromatography-consumables/consumable-types.html">solid-phase particles</a> that <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/chromatography/chromatography-learning-center/liquid-chromatography-information/hplc-system-components/how-hplc-columns-work.html">separate compounds by chemical structure</a>.If medium composition differs even slightly between manufacturing batches, retention times and peak shapes can change. These differences might seem minor, but in pharmaceutical analysis they can trigger failed validations, unnecessary troubleshooting, and inconsistent data across labs.A recent evaluation of<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/TG_20762_LC_Hypersil_GOLD_TG_20762_EN_ebcf64d4d6/TG-20762-LC-Hypersil-GOLD-TG20762-EN.pdf"> Thermo Scientific Hypersil GOLD columns</a> examined whether<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/lcms/products?category=48&amp;manufacturerItems=3&amp;search=gold"> these columns </a>perform consistently across years of production. The answer: our results found sustained performance over time.Across roughly 17,500 columns tested over three years, researchers focused on two major indicators of a manufacturer’s column performance:<ul><li>Relative retention time (RRT), which is essentially how consistently compounds elute off the column.</li><li>Peak asymmetry, a reflection of column packing quality and how well peaks “behave.”</li></ul>In a recent technical note: <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/tn_004127_ccs_hypersil_gold_reversed_phrase_reproducibility_tn004127_na_en_d6375a67fb.pdf">Evaluation of batch-to-batch consistency of reversed-phase HPLC columns for long-term method validation</a>, we evaluated three column configurations: a 250 mm × 4.6 mm, 5 μm column; a 150 mm × 4.6 mm, 5 μm column; and 50 mm × 2.1 mm, 5 μm column, using a test mixture of five compounds selected to represent different hydrophobicities.Despite differences in column geometry and media batches, the method produced highly consistent chromatographic performance.The method also achieved RRT relative standard deviation variation of no more than 2.11% for the compounds and kept peak asymmetry within a narrow range of 0.92 to 1.09. This level of control reduces uncertainty from long-term method validation, reinforcing confidence in predictable, reproducible column performance.<h3>Why column stability over time matters</h3>As an experienced analyst, you already know how frustrating <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/chromatography/chromatography-learning-center/liquid-chromatography-information/hplc-method-development-steps.html">method validation</a> can be. You think you’ve nailed the method, only to find the results from run to run. Often, the issue isn’t you. It’s the tools.When your column behaves the same every time, you will see several downstream benefits, such as:1. Improved confidence in data interpretationYou don’t have to keep wondering whether differences in your data are coming from your chemistry or your column.2. Methods stay valid longerPharmaceutical companies must monitor drug purity throughout the product lifecycle, from development to manufacturing to quality control. A column that performs consistently over time makes comparisons straightforward and reliable.3. Method transfer is more reliableLarge companies operate across multiple global sites. When everyone uses columns that behave consistently, transferring methods becomes seamless rather than a months-long headache.A closer look at column performance dataThe published technical note visualizes column performance using clean, simple charts (Figure 1).<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_What_Multi_Year_Batch_Data_Reveals_About_U_HPLC_Column_Consistency_18faa4e44c.jpg" alt="Thermo Fisher Scientific: What Multi-Year Batch Data Reveals About (U)HPLC Column Consistency: Figure 1.&nbsp; (Top image) Batch-wise average RRT, normalized by o-Xylene for Hypersil GOLDTM 250 mm x 4.6 mm 5 µm (83 batches). (Bottom image) Average peak asymmetry evaluation of o-xylene Hypersil GOLDTM 250 mm x 4.6 mm 5 µm (83 batches)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_What_Multi_Year_Batch_Data_Reveals_About_U_HPLC_Column_Consistency_18faa4e44c.jpg 245w," sizes="100vw" width="1000" height="600">These graphs show us:<ul><li>Tight clusters of RRT points across 83 batches, depending on column format.</li><li>Nearly identical behavior between columns of different dimensions, which is a sign of effective manufacturing process controls.</li><li>Peak asymmetry values hovering around 1.0, indicating well-packed columns producing sharp, reliable peaks.</li></ul>This data might not seem glamorous at first glance, but for anyone who’s spent hours troubleshooting peak tailing, drifting retention times, or inconsistent quality control (QC) results, these charts are beautiful.<h3>Why column consistency matters for long-term method performance</h3>In automated LC workflows, a small change in column behavior can affect multiple downstream outputs: integration, peak purity assessment, and calculated assay/impurity results. Over time, this can translate into system suitability failures, drift outside validated ranges, and additional validation or comparability work.Column stability and batch-to-batch reproducibility are therefore critical for sustaining validated methods over time. The multi-batch data presented here demonstrate how controlled manufacturing processes can maintain consistent retention behavior and peak shape over time.To learn how to test your column and determine what data to look for, read our technical note, <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/tn_004127_ccs_hypersil_gold_reversed_phrase_reproducibility_tn004127_na_en_d6375a67fb.pdf">Evaluation of batch-to-batch consistency of reversed phase HPLC columns for long-term method validation</a>.<h3>FAQs</h3><div><div><h5>1. How does batch-to-batch consistency in LC columns affect chromatographic results?</h5>Batch-to-batch consistency has a direct impact on the stability of chromatographic results. When columns are manufactured consistently, retention times remain stable and compounds elute at predictable intervals — run after run and batch after batch. This stability reduces unexpected shifts in selectivity or peak shape, helping analysts distinguish true method-related changes from column-related variability.</div><div><h5>2. How do you measure batch-to-batch consistency in LC columns?</h5>Batch-to-batch consistency is evaluated by applying the same standardized test method to columns produced across multiple manufacturing lots and by comparing key chromatographic performance metrics. Commonly monitored parameters include RRT, which reflects retention stability and peak asymmetry, which indicates packing quality and peak integrity. By tracking these metrics over many batches and extended production periods, manufacturers can quantify variability and ensure controlled, reproducible column performance.</div><div><h5>3. How does batch-to-batch LC column consistency support long-term method validation and transfer between laboratories?</h5>Consistent LC column performance plays an important role in sustaining validated methods over time, particularly in regulated pharmaceutical environments. When column behavior remains stable across production batches, methods are more likely to stay within established acceptance criteria, reducing the need for revalidation or investigation. This stability is especially valuable throughout the product lifecycle, from development through quality control and release testing. Batch-to-batch consistency also facilitates smoother method transfer between laboratories and global sites. When different labs use columns that perform the same way, chromatographic results are more predictable, making transfers faster, more efficient, and less prone to variability-related delays.</div></div><blockquote>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#UHPLC #ColumnsAndConsumables #pharmaceutical</blockquote>

What Multi-Year Batch Data Reveals About (U)HPLC Column Consistency

Chromatogram-based library searching can provide a fast first identification, but it does not always give analysts the flexibility needed to evaluate alternative candidates, adjust precursor settings, or choose different spectral comparison strategies. In his presentation, James Little of Mass Spec Interpretation Services shows how <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/Chromatogram_Sent_to_Lib_Search_d324bc4118.pdf">transferring chromatogram results into the standard NIST Library Search window</a> can expand the available search options and provide a more detailed view of potential compound matches.The workflow is particularly relevant when an analyst wants to go beyond the single best chromatogram result and investigate alternative library candidates, compare spectra using different scoring approaches, or perform MS/MS searches with greater control over precursor information.<h3>Why move from the chromatogram to Library Search?</h3>The chromatogram view is useful for rapid inspection, but according to the presentation, its library-search functionality is more limited.One of the main differences is that the chromatogram result list displays only the best library result, while the standard Library Search window provides access to alternative candidates. This can be important when several structures produce similar spectra or when the highest-ranked match needs additional scrutiny.The standard Library Search window also provides more control over MS/MS searching. While searches initiated directly from the chromatogram use the precursor information automatically supplied by the chromatogram, the Library Search window allows the user to work with different search modes and modify precursor settings where required.To transfer a component from the chromatogram into Library Search, the workflow shown in the presentation is straightforward: right-click the component of interest and select “Library Search.”<h3>Identity and similarity searches</h3>Once the spectrum has been transferred, the search settings determine how the library comparison is performed.With Identity selected, an MS/MS search can reproduce the type of search performed from the chromatogram. If the “In spectrum” option is enabled, the precursor sent from the chromatogram is used automatically. The option can also be disabled, allowing the analyst to enter a different precursor manually.An additional option is HiRes No Precursor. In this mode, the spectra are compared without restricting the search according to the precursor ion. The presentation highlights this approach as useful for obtaining substructural information, since the comparison is not constrained to entries matching a specified precursor.The Similarity mode provides access to Hybrid Search. Here again, the precursor imported from the chromatogram can be used automatically or replaced by another value. Hybrid Similarity itself is treated separately in the source presentation series, but its availability is one of the reasons for working in the full Library Search environment.<h3>Choosing the right spectral matching method</h3>The Library Search window also provides several ways to score spectral similarity:<ul><li>Full Spectrum Search</li><li>Impurity Tolerant Search (Reverse-Dot)</li><li>Partial Spectrum Search (PSS-Dot)</li></ul>Each is designed for a different analytical situation.<ul><li>Full spectrum matching compares the complete experimental and library spectra and is most appropriate when the acquired spectrum is clean and complete.</li><li>Reverse-Dot matching focuses primarily on whether important peaks from the library spectrum are present in the experimental spectrum. Extra peaks in the measured spectrum that are absent from the library spectrum are not penalized in the same way. This can make the approach more tolerant of chemical background or spectral contamination.</li><li>Partial Spectrum Search addresses the opposite situation. It does not strongly penalize library peaks that are missing from the experimental spectrum and is therefore suited to incomplete spectra, including cases where only a subset of fragment ions is observed, such as some MS/MS or filtered datasets.</li></ul>Although the results table can display multiple similarity metrics, the search method selected before the search begins is important because of the way Presearch operates.<h3>Why Presearch matters</h3>NIST uses a Presearch step to reduce the number of library spectra that require more detailed comparison.This significantly increases search speed, but it also means that spectra removed during Presearch will not appear later in the final results—even if another scoring metric might have ranked them favorably.This is why the presentation emphasizes choosing the appropriate search method before Presearch when Reverse-Dot or Partial Spectrum behavior is important.For example, running a standard Full Spectrum search and then sorting the final result table by Reverse-Dot does not necessarily reproduce the same candidate set that would have been obtained if an impurity-tolerant search had been selected from the beginning. Potentially relevant candidates may already have been excluded during the initial Presearch stage.For routine reviewing, the presentation recommends using the overall NIST Score as the primary sorting criterion, while remembering that specialized searches may require a different search strategy from the outset.<h3>Selecting libraries and mass tolerances</h3>Before running the search, analysts can specify which libraries should be included.The presentation illustrates the Library Search settings where individual spectral libraries can be added or removed from the search. This allows the search space to be tailored to the application rather than automatically searching every available library.For high-resolution MS/MS data, users can also configure mass tolerances for both precursor and product ions.These settings are particularly important because overly broad tolerances may increase the number of irrelevant candidates, while unnecessarily narrow tolerances could exclude valid matches. The appropriate values therefore need to reflect the quality and mass accuracy of the acquired data.The software also provides additional options associated with precursor handling and polarity matching.<h3>Understanding the result scores</h3>Once the search is complete, the result table can be customized to support efficient review.Properties can be added, reordered, resized, and used for sorting. The presentation notes that the results are normally best reviewed initially by Score.Two related measures discussed are the dot product and the NIST Score.The dot product reflects the direct similarity between two spectra based on shared peaks and their intensities. The NIST Score builds on this comparison by applying additional weighting and scaling. According to the presentation, this helps preserve useful matching performance when spectra are incomplete, as may occur with MS/MS or filtered spectral data.Analysts can also sort by Rev-Dot or Partial Spectrum Search (PSS) values. However, the limitations imposed by the initial Presearch still apply: sorting cannot recover candidates that were already removed before the detailed comparison stage.The result interface can also be navigated efficiently using the keyboard arrow keys, and the available display properties can be rearranged according to the analyst’s preferred review workflow.<h3>Additional filters for faster review</h3>The presentation also highlights two useful post-search filters:<ul><li>Best Matching Only</li><li>MS/MS Hit Filter List options</li></ul>Unlike Presearch, these filters are applied after the candidate search has already been completed. They can therefore be switched on and off without permanently removing candidates from the search process.The Best Matching Only option removes many duplicate results and can make the candidate list easier to review.The MS/MS Hit Filter provides additional filtering options for tandem MS results, including parameters related to instrument type and allowed precursor forms.James Little notes that he generally keeps these filters disabled initially and applies them only when needed. This approach preserves the complete search result set during the first review and allows filtering to be introduced later as a tool for improving efficiency.<h3>More flexibility for library-based identification</h3>The main advantage of moving chromatogram results into the full NIST Library Search window is not that the original chromatogram search is incorrect, but that the dedicated search environment gives the analyst more control over how the spectrum is interrogated.It allows alternative candidates to be reviewed, precursor restrictions to be modified, different identity and similarity strategies to be selected, and specialized full-spectrum, impurity-tolerant, or partial-spectrum comparisons to be performed.Just as importantly, the workflow highlights a subtle but important principle in spectral searching: the scoring method used to review results and the method used to generate the candidate set are not necessarily interchangeable. Because Presearch determines which library spectra proceed to detailed evaluation, analysts should choose the search strategy that best reflects the characteristics of their experimental spectrum before beginning the search.Used in this way, the NIST Library Search window can provide a more flexible and transparent workflow for investigating chromatographic components and evaluating MS/MS library matches.

 Searching Normal NIST Search with Chromatogram Results

Is your lab ready for the new academic year? As students and teachers return to the laboratory, now is a great time to prepare your chromatography systems for the semester ahead.Now with 20% total discount on a new <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/999">Clarity Chromatography Software</a> for customers from educational institutions. In addition, customers purchasing a new license for Clarity Chromatography Software will receive a free copy of <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1000">Clarity Offline Chromatography Software</a>.<blockquote>👉Promotion code: MKT2114The offer is valid through the end of October 2026.</blockquote>The latest version of Clarity Chromatography Software - 10.2 was released in June 2026! <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7512">Read the article HERE.</a>

Back to School: 20% Off Clarity Chromatography Software

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Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

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A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

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James Little/Mass Spec Interpretation Services

SIELC Alltesta Mini HPLC Autosampler

The Alltesta™ Mini Autosampler is an affordable and dependable solution for automated sample handling in various analytical and liquid handling applications, including HPLC.

The Alltesta™ Mini Autosampler is an affordable and dependable solution for automated sample handling in various analytical and liquid handling applications, including HPLC. With its proprietary alpha/beta mechanical design, this compact autosampler offers direct and comprehensive control of its features, making integration quick and easy. Users can tailor the mini autosampler to their needs with customizable valve configurations, tray designs, and syringe volumes and pressures. Additionally, a built-in shaking feature enables sample mixing before injection and/or simple sample extraction within the vial.
This compact autosampler comes designed with original equipment manufacturer (OEM) customization in mind. Custom shape, color, and communication interfaces can be adapted to integrate with any system. Comprehensive software integration support is provided. Other options include metal-free sampling and reagent addition and mixing capabilities.
<ul>
<li>FRACTION COLLECTION CAPABILITY: A simple software modification can quickly convert this small autosampler into a fraction collector.
</li>
<li>REACTOR PROBE SAMPLER CAPABILITY: A simple software modification can quickly convert this small autosampler into a reactor probe sampler.
</li>
</ul>
This miniature autosampler can also be used as a component of our <a href="https://lcms.labrulez.com/products/1242">Alltesta™ Gradient Automated Analyzer</a> and <a href="https://lcms.labrulez.com/products/1243">Alltesta™ Cromite Analyzer</a>.
<blockquote>
<h4>The price of the Alltesta™ Mini Autosampler varies depending on the specific configuration requested.</h4>
</blockquote>
<h4>Specifications</h4>
<ul>
<li>Dimensions (WHL): 160 x 145 x 195 mm / 6.3 x 5.71 x 7.68 in</li>
<li>Weight: 3 kg / 6.6 lb</li>
<li>Power: 24 V</li>
<li>Capacity: 48 vials or 96-well plate</li>
<li>Pressure: 5000 psi</li>
<li>Needle Wash: Inside and outside</li>
<li>Syringe Capacity: 120µL high-pressure / 4000µL low-pressure stainless / 4000µL low-pressure ceramic</li>
<li>Valve options: 6×2, 7×6 and 10×9 (more details here).</li>
<li>Volume Accuracy: 0.1µL</li>
<li>Communication: RS232 Virtual COM port via USB</li>
</ul>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SIELC_Alltesta_Mini_Autosampler_A_very_simple_schematic_operation_of_the_Alltesta_Autosampler_b79b0ad187.jpg" alt="SIELC: Alltesta™ Mini Autosampler - A very simple schematic operation of the Alltesta™ Autosampler."/>
<h4>Software</h4>
The Alltesta™ Autosampler can be controlled:
<ul>
<li>directly via serial commands (Alltesta™ protocol available upon request, please contact us at support@sielc.com),</li>
<li>directly via our demo software, allowing to learn the whole functionality of the unit (<a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Autosampler_Control_Windows_10.zip">Windows 10, 32/64bit</a>, 5Mb; <a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Autosampler_Control_Windows_7.zip">Windows 7, 32/64bit</a>, 126Mb).</li>
<li>remotely through our cloud software (as a part of Alltesta™ Analyzer or Alltesta™ Mini Analyzer),</li>
</ul>
Serial communication drivers are available <a href="https://ftdichip.com/drivers/vcp-drivers/">here</a>.

SIELC Alltesta™ Mini LHS (Liquid Handling Station)

The Alltesta™ Mini Liquid Handling Station serves as an affordable, reliable solution for automated sample handling.

The Alltesta™ Mini Liquid Handling Station serves as an affordable, reliable solution for automated sample handling. With its compact design, proprietary alpha/beta mechanical structure, and adjustable operation speeds, it offers comprehensive control for quick and seamless integration with other equipment. The station comes equipped with a built-in sample shaking feature for in-vial sample mixing and extraction, and a needle washing station capable of accommodating up to four solvents.
Designed with Original Equipment Manufacturer (OEM) customization in mind, the Alltesta™ Mini Liquid Handling Station can be tailored to fit any system’s requirements. Custom needle lengths and trays enable the device to accommodate various types of vials. An array of integrated valves and a measuring syringe can be added to the device. Additional customization options, such as metal-free flow paths and customer-specified enclosure colors, are also available.
Comprehensive software integration support is provided to ensure smooth operation and functionality.
<h4>Specifications</h4>
<ul>
<li>Dimensions (WHL): 160 x 145 x 195 mm / 6.3 x 5.71 x 7.68 in</li>
<li>Weight: 2.25 kg / 5 lb</li>
<li>Power: 24 V</li>
<li>Capacity: 48-vial tray or 96-well plate</li>
<li>Needle Wash: Inside and Outside</li>
<li>Communication: RS232 Virtual COM port via USB</li>
</ul>
<h4>Software</h4>
The Alltesta™ LHS can be fully controlled via serial commands. Alltesta™ protocol available upon request, please contact us at support@sielc.com. Serial communication drivers are available <a href="https://ftdichip.com/drivers/vcp-drivers/">here</a>.

SIELC Samplify Automated sampling system

Samplify Is a device which allows unattended sampling of a reaction mixture or bioprocess or continue in line flow by taking small amount of liquid from the monitoring mixture and collecting it in a vial or a 96 wells plate

Samplify™ Is a device which allows unattended sampling of a reaction mixture or bioprocess or continue in line flow by taking small amount of liquid from the monitoring mixture and collecting it in a vial or a 96 wells plate. It also allows to dilute the sample with assigned dilution ratio and can provide reaction quenching to preserve the sample state at time of sampling. It has two main components: an autosampler and a probe. The Samplify™ &nbsp;controlled and setup by a PC software.<h3>Description</h3>It is a common task in the lab to periodically sample a reactor or a fermenter to obtain information about reaction kinetic, completion and have a tangible representation of intermediate states of a dynamic process. This usually done manually with pipettes or syringes, using stopwatch to measure time and requires to be in the lab during the entire process.With Samplify it can be done in automated mode. When an automated sampling process is used it increases accuracy, safety, and productivity. It reduces potential samples cross contamination, and exposure of the reaction mixture to oxygen or moisture, when anaerobic or moisture free conditions are required.<ul><li>Based on a proprietary alpha/beta mechanical configuration, Alltesta Miniature Autosampler and patent pending sample probe offers affordable and reliable automation for many analytical and liquid-handling applications.&nbsp;</li><li>Small controllable volume of sample can be programmed and precisely removed from the enclosed or open system. The sample will then be transferred to a vial with inert solvent with measured volume to create a controllable dilution factor.</li><li>A quench solution can be automatically preloaded in each vial to provide termination of reaction or biological process, and preserve sample content in the time of probing.</li><li>In order to effectively mix samples with diluents or quenching reagents a shaking capability of the autosampler tray can be initiated after each sample cycle.</li><li>PC based software allows quick, but flexible, setup of the sampling experiment. Several preloaded methods can be quickly adapted to a particular needs of the user.</li><li>For temperature sensitive samples the entire autosampler can be placed in the temperature controlled environment.</li><li>The device small size allow to place it close to the reactor and use short connection lines to minimize dispersion. Also a small cooler can be used to keep samples in cold conditions after they are collected.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/SIELC_SIELC_Samplify_Automated_sampling_system_937b70e8d2.jpg" alt="SIELC: SIELC Samplify™ Automated sampling system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_SIELC_SIELC_Samplify_Automated_sampling_system_937b70e8d2.jpg 245w," sizes="100vw" width="1346" height="663"><h3>Specifications</h3><h4>Samplify™ Autosampler:</h4><ul><li>Syringe volume: 4.0 mL</li><li>Pressure: up to 250 psi</li><li>Valve configuration: 7×6</li><li>Power Requirements: 24 VDC</li><li>Current Requirements: Up to 1.0 A</li><li>Dimensions (WHL): 160 x 145 x 195 mm / 6.3 x 5.71 x 7.68 in</li><li>Weight: &nbsp;3 kg / 6.6 lb</li><li>Inlets/Outlets: Thread 10-32 UNF compression type</li><li>Materials in contact with liquid: SS316, PTFE, PEEK</li><li>Tray capacity: 48 vials 1.8 mL volume or 96 wells plate</li><li>Communication: USB virtual serial port</li></ul><h4>Samplify™ Probe:</h4><ul><li>Connection: requires Alltesta-Samplify autosampler</li><li>Dimensions: 1 x 1 inch, DIA ¼ inch. Immersion length up to 6 inch</li><li>Materials in contact with liquid: Stainless Steel 316 (316L), PEEK &amp; PTFE</li><li>Variable sample volume: from 5 to 500 µL</li><li>Max. working pressure: 120 psi (8 bar)</li><li>Max. working temperature: &nbsp;200 °C</li></ul><h3>Software</h3>The Samplify can be controlled:<ul><li>directly through your software via serial commands (Alltesta™ protocol available upon request, please contact us at support@sielc.com),</li><li>remotely through our cloud software (autosampler.cloud),</li><li>directly via our Samplify PC software, allowing to fully control all the parameters of the sampling operations</li></ul><h3>Available Custom Options</h3>Metal-free version of the syringe pump includes no metal contact pump head.

Products from category Sample preparation automation from SIELC - page 1

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Back to School: 20% Off Clarity Chromatography Software

What Multi-Year Batch Data Reveals About (U)HPLC Column Consistency

Searching Normal NIST Search with Chromatogram Results