Nutrient imbalances caused by industrial pollution were not affected by extreme climate events 

<p><strong>In the week from November 2, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>6 000 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><div><div><div><div><h5><span><strong>1. Technology Networks: When Good Analytical Methods Become a Problem</strong></span></h5><ul><li><div><div><span>Tu, 3.11.2026 18:00 CET</span></div></div></li><li><div><div><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6678"><span>Registration</span></a></div></div></li></ul><p>Join our webinar on analytical method lifecycle management in biopharmaceuticals. Learn when and why to reassess established methods for QC and transfer.</p></div><div><h5><span><strong>2. C&amp;EN: From Reaction to Release: Raman and NIR Analysis for Fertilizer Production</strong></span></h5><ul><li><div><div><span>We, 4.11.2026 19:00 CET</span></div></div></li><li><div><div><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6698"><span>Registration</span></a></div></div></li></ul><p>Learn how Raman and NIR spectroscopy can accelerate fertilizer production analysis, reduce reagent use, and support reliable quantitative measurements for phosphate, urea, and ammonium nitrate.</p></div><div><h5><span><strong>3. Metrohm: Bring Your Work to Kids: Test, Don't Guess</strong></span></h5><ul><li><div><div><span>Th, 5.11.2026 10:00 CET</span></div></div></li><li><div><div><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6699"><span>Registration</span></a></div></div></li></ul><p>Join Metrohm and RI Analytical for a fun 30-minute science experience where kids become science detectives and discover how analytical testing helps keep water, toys, and everyday products safe.</p></div><div><h5><span><strong>4. AZoM: Gas Analysis Across Semiconductor Manufacturing: From Bulk Gas Quality to Process Emissions</strong></span></h5><ul><li><div><div><span>Th, 5.11.2026 17:00 CET</span></div></div></li><li><div><div><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6682"><span>Registration</span></a></div></div></li></ul><p>Join the Thermo Fisher Scientific webinar on semiconductor gas analysis. Discover APIX UHP and MAX-iR FTIR for high-purity gas and emissions control.</p></div></div></div></div>

Webinars LabRulezICPMS Week 45/2026

<p><strong>Sample dilution is a routine part of elemental analysis—but it can also become a significant source of manual work, variability, and laboratory bottlenecks. When samples fall outside the calibration range, contain high particulate loads, or require different dilution factors, analysts may need to stop a sequence, prepare new dilutions, and repeat measurements.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Reducing_Errors_and_Increasing_Throughput_in_ICP_MS_and_ICP_OES_with_Automated_Dilution_61d41669d9.webp" alt="Thermo Fisher Scientific: Reducing Errors and Increasing Throughput in ICP-MS and ICP-OES with Automated Dilution" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Reducing_Errors_and_Increasing_Throughput_in_ICP_MS_and_ICP_OES_with_Automated_Dilution_61d41669d9.webp 245w," sizes="100vw" width="1024" height="512"></p><p>The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2637"><strong>prepFAST 3 autodilution system</strong></a> is designed to bring dilution directly into the analytical workflow, combining high-throughput sample introduction with automated dilution for<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/products?category=232&amp;manufacturerItems=3&amp;search=icap"><strong>ICP-MS</strong></a> and <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/products?category=227&amp;manufacturerItems=3"><strong>ICP-OES</strong></a> analysis. The system supports both undiluted FAST analysis and diluted sample analysis, allowing laboratories to handle different sample requirements within a single automated workflow.</p><h3><strong>From manual dilution to an automated workflow</strong></h3><p>With prepFAST 3, samples can either be introduced undiluted or diluted automatically before analysis. For undiluted samples, the system loads the sample and injects it for analysis using the FAST workflow. When a dilution factor greater than one is required, the sample is loaded into the dilution line, diluted by syringe into the sample line, and then injected for analysis.</p><p>Integration with <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1489"><strong>Thermo Scientific Qtegra Intelligent Scientific Data Solution Software</strong></a> extends this automation into the analytical method itself. Users can prescribe dilution factors for standards and samples directly in the sample list.</p><p>More importantly, dilution can respond to analytical results. If an analyte exceeds method-defined quality-control levels, the sample can be automatically returned to the sample list and reanalyzed at a higher dilution factor until its concentration falls within the specified range.</p><p>This turns dilution from a separate sample-preparation step into part of the analytical decision-making process.</p><h3><strong>Intelligent QC-driven dilution</strong></h3><p>Automation becomes particularly valuable when unexpected samples enter a sequence. Instead of requiring an analyst to identify an over-range result, prepare another dilution, and restart the analysis, Qtegra and prepFAST 3 can trigger reanalysis based on user-defined criteria.</p><p>The workflow can also respond to internal-standard recovery. If internal-standard recovery fails, prepFAST can rerun the sample using a prescribed dilution and continue doing so up to a user-defined maximum. Likewise, when an elemental concentration exceeds the calibration range, the system can trigger reanalysis through the Intelligent Dilution functionality, with the reanalysis limits and target range defined by the user.</p><p>The result is an analytical workflow designed to reduce manual intervention while keeping dilution decisions tied to predefined method and QC criteria.</p><h3><strong>Keeping challenging samples moving</strong></h3><p>Automation is only useful if the sample introduction system can keep running. High-particulate, unfiltered, and fiber-containing samples can present a particular challenge because particles may clog valves or nebulizers.</p><p>The prepFAST 3 <strong>FilterProbe</strong> addresses this at the autosampler probe. An inline CTFE filter traps larger particles and fibers before they reach downstream components. While the sample is being analyzed, the filter is rapidly backflushed at the waste station using a syringe-driven process, preparing the system for the next sample. As illustrated by the brine pipeline sludge example on page 12, the concept is intended to extend automation even to highly challenging, particulate-rich samples. The presentation notes that this approach can help minimize valve and nebulizer maintenance while maintaining high throughput.</p><h3><strong>Knowing whether the sample actually loaded</strong></h3><p>Another potential source of analytical problems is incomplete sample loading. <strong>SampleSense3</strong> adds sensor-based monitoring to the workflow. It detects samples, accounts for viscosity by adjusting loading timing, and can detect and log incomplete loading caused by conditions such as a clogged filter, capped vial, or empty vial.</p><p>That capability helps shift the workflow from simply automating physical sample movement toward monitoring whether the automated process is functioning as intended.</p><h3><strong>Designed around uptime and usability</strong></h3><p>prepFAST 3 also introduces hardware features intended to simplify routine operation and maintenance. Multiposition Magnetic SnapValves can be removed without tools and use a two-valve sampling architecture for FAST and prepFAST operations.</p><p>High-purity quartz syringes are used for dilution and sample carrier delivery, with 6 mL and 3 mL syringe configurations respectively. The system also incorporates a hinged, single-screw mounting design intended to simplify syringe maintenance and replacement.</p><p>Together with features such as FilterProbe, SampleSense3 and a shortened probe configuration, these elements are designed around a practical laboratory objective: keeping automated analytical sequences running with less intervention.</p><h3><strong>More analysis, less sample handling</strong></h3><p>For laboratories processing large numbers of samples by ICP-MS or ICP-OES, improving productivity does not necessarily mean making the measurement itself faster. Significant gains can come from reducing the manual steps surrounding each measurement.</p><p>By combining <strong>high-throughput sample introduction, prescribed and QC-driven autodilution, automated reanalysis, particulate management, and sample-loading monitoring</strong>, prepFAST 3 moves several traditionally manual activities into the analytical sequence itself. The objective is straightforward: rapidly analyze both diluted and undiluted samples while improving the user experience and maintaining a compact laboratory footprint.</p><p>For elemental-analysis laboratories looking to reduce repetitive sample preparation and increase unattended operation, automated dilution offers a way to make the workflow—not just the instrument—more efficient.</p><h5><strong>Acknowledgement</strong></h5><p>I would like to thank <strong>Torben Stichel, Joerg Axthelm and Sebastian Voelker </strong>Field Applications Scientist, Germany, Trace Elemental Analysis and for the support on this blog and the webinars</p><h3><strong>References:</strong></h3><ul><li>Watch this webinar on demand in German language: <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179292/AE4C576B6A54D1AC182F7F77573D380F"><strong>Fehler reduzieren, Durchsatz steigern: Autoverdünnung mit PrepFast am ICP-MS</strong></a></li><li>Product Spotlight:<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/sl_004425_intelligent_autodilution_esi_prepfast3_sl004425_en_0d3490e91e.pdf"><strong>Qtegra Intelligent Scientific Data Solution Software</strong></a></li><li>Sign up for our webinars live and on demand</li></ul><h5><strong>English</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/5795"><strong>Lunch and Learn Tips and Tricks Series: Qtegra Part 1</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/5976"><strong>Lunch and Learn Tips and Tricks Series: Qtegra Part 2</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/5977"><strong>Lunch and Learn Tips and Tricks Series: Trace Elemental Analysis (ICP-OES &amp; ICP-MS)</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/5978"><strong>Trace Elemental Analysis: Ask the Expert</strong></a></li></ul><h5><strong>Deutsch</strong></h5><ul><li><strong>19. März 2026</strong><br><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179134/393E071E3B501943730958BA6203F477"><strong>Interne Standards in der ICP-OES: Ein Praxisguide für zuverlässige Qualitätssicherung im Labor</strong></a></li><li><strong>18. Juni 2026</strong><br><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179292/AE4C576B6A54D1AC182F7F77573D380F"><strong>Fehler reduzieren, Durchsatz steigern: Autoverdünnung mit PrepFast am ICP-MS</strong></a></li><li><strong>17. September 2026</strong><br><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179423/B5019C560431BADCA2A76E54E4EFE56F"><strong>ICP-OES smarter nutzen: Probendurchsatz erhöhen, Ressourcen sparen</strong></a></li><li><strong>17. Dezember 2026</strong><br><a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/wcc/r/5179530/94EEDD1F56138F5EEE2AF24E29E6C12A"><strong>Qtegra ISDS Software Unlocked – Live im Expertengespräch</strong></a></li></ul><blockquote><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/chromatography-&amp;-mass-spectrometry/posts/?feedView=all"><strong><u>LinkedIn:</u></strong></a><strong>&nbsp;</strong>#ICPMS #ICPOES #AutomatedDilution #LabAutomation</p></blockquote>

Reducing Errors and Increasing Throughput in ICP-MS and ICP-OES with Automated Dilution

Article

Product

Webinars

Video

Scientific article

Science and research

A unique company dedicated to serving science helping our customers drive productivity and accelerate results. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services.

Thermo Fisher Scientific

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Thermo Scientific DXR3xi Raman Imaging Microscope

High-performance Raman imaging microscope offering fast, non-destructive 2D and 3D chemical imaging with intuitive workflows, automated calibration, and advanced data visualization.

<p><strong>The Thermo Scientific™ DXR3xi Raman Imaging Microscope delivers research-grade Raman imaging faster than ever before. Enhanced software features combined with higher spatial resolution allow users to instantly obtain detailed visual and chemical information. Advanced imaging capabilities, minimal sample preparation, and intuitive software provide researchers with the power of Raman spectroscopy at the speed modern research demands.</strong></p><h3><strong>Key features and benefits</strong></h3><ul><li><strong>Simple operation</strong> suitable for users of all skill levels</li><li><strong>Faster data visualization</strong> enabled by advanced imaging software<ul><li>Advanced particle analysis for rapid identification and analysis of microscopic contaminants</li><li>3D confocal imaging for non-destructive, non-invasive three-dimensional chemical and molecular investigations</li><li>Terrain Mapping to characterize uneven sample surfaces and easily acquire in-focus Raman images</li></ul></li><li><strong>Intuitive workflow</strong> designed for demanding applications to maximize sample throughput</li><li><strong>Automated calibration</strong> to improve efficiency</li><li><strong>High measurement accuracy</strong> supported by:<ul><li>Automatic alignment and calibration with no tools required</li><li>Automatic background compensation</li></ul></li><li><strong>Rapid system reconfiguration</strong> within seconds – pre-aligned lasers, filters, and gratings can be changed without tools</li><li><strong>Fast spectral analysis and interpretation</strong> using powerful <strong>Thermo Scientific™ OMNIC™xi Software</strong></li><li><strong>Advanced autofocus and morphological analysis</strong> to track positions across uneven surfaces</li><li><strong>Visualization tools</strong> for extracting chemical contrast and identifying and ranking features of interest</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_DXR_3xi_Raman_Imaging_Microscope_8_9021ee32c0.jpg" alt="Thermo Scientific DXR3xi Raman Imaging Microscope " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_DXR_3xi_Raman_Imaging_Microscope_8_9021ee32c0.jpg 234w," sizes="100vw" width="650" height="433"></p><h3><strong>Laser safety</strong></h3><ul><li>Microscope designed and independently certified as <strong>Class 1 laser safe</strong></li><li>Optional fiber optic accessories and selected components are <strong>Class 3b laser devices</strong>, requiring appropriate laser safety measures and protective eyewear</li><li>Laser path is physically blocked from the visual viewing path to prevent eye exposure during observation</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_DXR_3xi_Raman_Imaging_Microscope_4_73e61c6ef9.jpg" alt="Thermo Scientific DXR3xi Raman Imaging Microscope " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_DXR_3xi_Raman_Imaging_Microscope_4_73e61c6ef9.jpg 236w," sizes="100vw" width="650" height="430"></p><h3><strong>Applications</strong></h3><ul><li>Nanotechnology</li><li>Microplastics analysis</li><li>Polymer and chemical analysis</li><li>Electronics</li><li>Materials science</li><li>Academic research</li><li>Pharmaceutical research</li><li>Geology</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_DXR_3xi_Raman_Imaging_Microscope_9_5d3708416c.jpg" alt="Thermo Scientific DXR3xi Raman Imaging Microscope " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_DXR_3xi_Raman_Imaging_Microscope_9_5d3708416c.jpg 156w," sizes="100vw" width="650" height="650"></p><h3><strong>Specifications</strong></h3><ul><li><strong>Electrical Requirements</strong>: 100/240 V, 47/63 Hz</li><li><strong>Electronic Records and Signatures</strong>: 21CFR Part 11</li><li><strong>For Use With (Application)</strong>: Nanotechnology, Material science, Academic research, Pharmaceutical, Geology, Microplastics, Polymer/Chemical and Electronics</li><li><strong>Laser Power</strong>: Fine Laser Power Control: Power controlled and reported at samples in 0.1 mW increments</li><li><strong>Model</strong>: DXR3xi Raman Imaging Microscope</li><li><strong>Operating Temperature Range</strong>: 16°C to 27°C</li><li><strong>Resolution</strong>: Spatial: 0.5 µm; Confocal Depth: 2 µm</li><li><strong>Software Details</strong>: Data analysis and spectral interpretation with powerful Thermo Scientific™ OMNIC™xi Software</li><li><strong>Wavelength Range</strong>: 455 nm; 532 nm high brightness; 532 nm high power; 633 nm high brightness; 633 nm high power; 780 nm</li><li><strong>Type</strong>: Raman Imaging Microscope</li><li><strong>Unit Size</strong>: Each</li></ul>

Thermo Scientific DXR3 Raman Microscope

The Thermo Scientific DXR3 Raman Microscope is an easy-to-use confocal Raman system with automated calibration, high stability, and flexible laser options for a wide range of applications.

<p><strong>The </strong><span><strong>Thermo Scientific</strong></span><strong>™ DXR3 Raman Microscope is a modern, easy-to-use point-and-shoot Raman microscope designed to provide faster, more reliable access to Raman data than ever before. Advanced imaging capabilities combined with automated system calibration deliver exceptional stability, reproducibility, and confidence in Raman measurements—even for non-specialist users.</strong></p><p>Thanks to Automated X-axis Calibration, the DXR3 system maintains long-term accuracy and reliability while minimizing user intervention. With a flexible choice of lasers and gratings, the DXR3 Raman Microscope is ideally suited for applications across pharmaceutical research, academia, advanced polymers, microplastics, and many other demanding fields.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_DXR_3_Raman_Microscope_6_1dd5de4a21.jpg" alt="Thermo Scientific DXR3 Raman Microscope" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_DXR_3_Raman_Microscope_6_1dd5de4a21.jpg 245w," sizes="100vw" width="650" height="299"></p><h3><strong>Key capabilities</strong></h3><ul><li>New <strong>Particle Analysis</strong> functionality for rapid identification and analysis of microparticles</li><li>High-performance <strong>confocal Raman microscopy</strong> in a robust, fully integrated design</li><li>Fully automated <strong>alignment and calibration</strong> with no tools or manual procedures required</li><li>Real-time preview, automated fluorescence correction, auto-exposure, and cosmic ray rejection</li><li>System status indicator providing at-a-glance confirmation that the instrument is optimized and ready for data acquisition</li><li>Three-path fine-beam autoalignment to maintain peak performance and sampling integrity</li><li>Active laser power regulation ensuring consistent sample excitation throughout the lifetime of the laser</li><li>Advanced spectrograph design with no moving parts for simplified operation and highly robust detection and calibration</li><li>Pre-aligned, lock-in-place components with automatic recognition and stored alignment, enabling system reconfiguration in seconds</li><li>Interchangeable lasers and components shared across the DXR3 Raman family</li><li>Optional automated <strong>polarized Raman spectroscopy</strong> for structural information complementary to chemical data</li><li>Add new excitation wavelengths without tools or service engineer intervention</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_DXR_3_Raman_Microscope_2_e366caa151.jpg" alt="Thermo Scientific DXR3 Raman Microscope" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_DXR_3_Raman_Microscope_2_e366caa151.jpg 204w," sizes="100vw" width="631" height="483"></p><h3><strong>Laser safety</strong></h3><ul><li>Microscope independently certified as <strong>Class 1 laser safe</strong><br><i>(Note: optional fiber-optic accessories and certain other optional components are Class 3B laser devices and require appropriate laser safety precautions and eyewear)</i></li><li>Laser is physically blocked from the visual viewing path, preventing eye exposure during sample observation</li></ul><h3><strong>Validation and compliance</strong></h3><ul><li>Complete <strong>DQ/IQ/OQ/PQ validation</strong> package available, including extensive documentation and automated software protocols</li><li><strong>OMNIC™ D/S software</strong> supports compliance with <strong>21 CFR Part 11</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_DXR_3_Raman_Microscope_3_62f6baad12.jpg" alt="Thermo Scientific DXR3 Raman Microscope" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_DXR_3_Raman_Microscope_3_62f6baad12.jpg 178w," sizes="100vw" width="630" height="553"></p><h3><strong>Exceptional analytical performance</strong></h3><ul><li>Spatial resolution down to <strong>540 nm</strong> on ideal samples</li><li>Confocal depth resolution as fine as <strong>1.7 µm</strong> on ideal samples</li><li>Full spectral range of <strong>3500–50 cm⁻¹</strong> captured in a single CCD exposure, eliminating stitching artifacts</li><li>Extended spectral range up to <strong>6000 cm⁻¹</strong> available with the 532 nm laser</li><li>Support for multiple excitation lasers: <strong>455, 532, 633, and 785 nm</strong> (high-brightness and high-power options)</li><li>Automatic fluorescence correction available for all excitation lasers</li><li>Research-grade <strong>Olympus</strong> viewing optics</li><li>Automatic intensity correction enabling spectral comparability between instruments and across different excitation lasers</li><li>Multidimensional wavelength calibration ensuring accurate calibration across the entire spectral range</li><li>Proprietary <strong>Triplet spectrograph</strong> delivering exceptional peak shape and maintaining focus at all wavelengths</li><li>Software-controlled switching between confocal and high-energy collection modes</li><li>Proprietary algorithms for automated cosmic ray rejection and high-quality laser line filters for artifact-free spectra</li><li>Depolarized lasers to eliminate confusing sample orientation effects</li><li>Active laser power monitoring ensures reproducible excitation power over the laser lifetime and after laser replacement</li><li>Optimized gratings for each excitation laser, avoiding performance compromises associated with shared gratings</li><li>Proprietary autoalignment maintains the system in like-new condition</li><li>Smart-Backgrounds technology automatically removes the CCD dark energy profile</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_DXR_3_Raman_Microscope_5_ca01560747.jpg" alt="Thermo Scientific DXR3 Raman Microscope" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_DXR_3_Raman_Microscope_5_ca01560747.jpg 210w," sizes="100vw" width="633" height="471"></p><h3><strong>Recommended applications</strong></h3><ul><li><strong>Forensics</strong> – trace evidence analysis and illicit drug identification</li><li><strong>Pharmaceuticals</strong> – polymorphism studies, particulate contamination, and diffusion analysis</li><li><strong>Art restoration and conservation</strong> – identification and characterization of pigments, resins, glazes, and inks</li><li><strong>Archaeology</strong> – characterization of horn, shell, bone, and ceramic artifacts</li><li><strong>Solar materials</strong> – silicon crystallinity and photovoltaic material characterization</li><li><strong>Polymers</strong> – inclusions, gel defects, weathering effects, laminate layers, and crystallinity</li><li><strong>Failure analysis</strong> – characterization of particulates and small surface features</li><li><strong>Gemology</strong> – rapid identification of colored stones, differentiation of natural and synthetic diamonds, characterization of inclusions and adulterants</li><li><strong>Nanotechnology</strong> – graphene, carbon nanotubes (CNTs), DLC coatings, and other nanostructures</li><li><strong>Academic research</strong> – materials science, biological studies, and a wide range of applied research fields</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_DXR_3xi_Raman_Imaging_Microscope_9_5d3708416c.jpg" alt="Thermo Scientific DXR3 Raman Microscope" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_DXR_3xi_Raman_Imaging_Microscope_9_5d3708416c.jpg 156w," sizes="100vw" width="650" height="650"></p><h3><strong>Specification</strong></h3><ul><li><strong>Depth (Metric):</strong> 68 cm</li><li><strong>Description:</strong> DXR3 Raman Microscope</li><li><strong>Electrical Requirements:</strong> 100/240 V, 47/63 Hz</li><li><strong>Electronic Records and Signatures:</strong> 21CFR Part 11</li><li><strong>For Use With (Application):</strong>&nbsp;<ul><li>Pharmaceutical</li><li>Microplastics</li><li>Forensics</li><li>Polymer/Chemical</li><li>Petrochemical</li><li>Material Science</li><li>Nanomaterials</li><li>Academia</li><li>Energy Storage</li><li>Art Restoration/Conservation</li></ul></li><li><strong>Height (Metric):</strong> 61 cm</li><li><strong>Laser Power:</strong> Fine Laser Power Control: Power controlled and reported at samples in 0.1 mW increments</li><li><strong>Model:</strong> DXR3</li><li><strong>Operating Temperature Range:</strong> 16°C to 27 °C</li><li><strong>Resolution:</strong>&nbsp;<ul><li><strong>Spatial:</strong> 1 µm</li><li><strong>Confocal Depth:</strong> 2 µm</li></ul></li><li><strong>Wavelength Range:</strong>&nbsp;<ul><li>455 nm</li><li>532 nm high brightness</li><li>532 nm high power</li><li>633 nm high brightness</li><li>633 nm high power</li><li>780 nm</li></ul></li><li><strong>Weight (Metric):</strong> 66.5 kg</li><li><strong>Width (Metric):</strong> 94 cm</li><li><strong>Type:</strong> Microscope</li><li><strong>Unit Size:</strong> Each</li></ul>

Thermo Scientific Nicolet RaptIR + FTIR Microscope

The Thermo Scientific™ Nicolet™ RaptIR™ + FTIR Microscope combines high-resolution imaging, fast spectral mapping, user-swappable detectors and automated controls for efficient sample analysis.

<p><strong>The Thermo Scientific™ Nicolet™ RaptIR™ + FTIR Microscope is designed for precision and agility, helping users locate and analyze areas of interest within a sample and obtain results efficiently. High-resolution visible imaging, infrared capability, user-swappable detectors and automated microscope controls support a streamlined workflow from sample viewing and targeting to spectral collection, analysis and reporting.</strong></p><p>Designed for specialists and non-specialists alike, the microscope is adaptable across a wide range of industries and applications, including pharmaceuticals, environmental analysis, forensics and materials research. <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2456"><strong>Thermo Scientific™ OMNIC™ Paradigm Software</strong></a> supports the navigation and analysis of complex samples through an adaptive user interface and integrated tools for data collection and analysis.</p><h4><span><strong>Key Features</strong></span></h4><ul><li><strong>Clear sample visualization:</strong> A high-resolution 5 megapixel camera, eyepieces and the mosaic feature provide a clear overview of the sample and help users locate specific areas of interest.</li><li><strong>Automated microscope controls:</strong> A motorized multi-position nosepiece, autofocus, automatic illumination and a computer-controlled aperture simplify microscope operation and sample targeting.</li><li><strong>Versatile sampling modes:</strong> Reflectance, transmission and ATR sampling modes with automated exchange provide flexibility for different analytical requirements. Built-in ATR sensors help protect samples and provide sensitive pressure control.</li><li><strong>Open-access sample stage:</strong> The heavy-duty stage accommodates samples up to 40 mm thick and 5 kg in mass while providing convenient access for sample loading.</li><li><strong>Fast spectral mapping:</strong> Data can be collected at up to 10 spectra per second for efficient analysis of larger sample areas.</li><li><strong>Optional polarization:</strong> Automated visible and infrared polarizers provide additional detail when examining samples.&nbsp;</li></ul><h4><span><strong>User-Swappable Detector Options</strong></span></h4><p>The Nicolet RaptIR + offers user-swappable detectors for different analytical requirements:</p><ul><li><strong>MCT-A, liquid nitrogen cooled:</strong> Provides high sensitivity across the mid-infrared range and is suited to general-purpose microscopy, small spot sizes and high signal-to-noise performance.</li><li><strong>MCT-B, liquid nitrogen cooled:</strong> Offers good sensitivity with a wider spectral range.</li><li><strong>InGaAs, room temperature:</strong> Extends measurements into the near-infrared region and is suited to applications such as pharmaceutical analysis, moisture mapping and polymerization studies.&nbsp;</li></ul><h4><span><strong>OMNIC Paradigm Software</strong></span></h4><p><strong>Thermo Scientific™ OMNIC™ Paradigm Software</strong> provides an adaptive user interface with a floating toolbar that presents functions relevant to the current task. Workflows can be created to automate data collection and analysis sequences, while the software also supports the collection and analysis of large-area maps and thousands of microparticles.</p><p>Data are stored in a secure database system, and results can be transferred into a variety of formal and customizable reporting formats.</p><h4><span><strong>Applications</strong></span></h4><p>The adaptable design of the Nicolet RaptIR + supports applications across a wide range of industries:</p><ul><li><strong>Pharmaceuticals:</strong> Analysis of API distribution and purity, as well as collection of high-quality IR data across entire tablets.</li><li><strong>Environmental analysis:</strong> Examination of microplastic samples and targeting of individual particles.</li><li><strong>Forensics:</strong> Investigation of counterfeit materials, identification of inks on paper and analysis of trace evidence.</li><li><strong>Polymers and materials:</strong> Analysis of polymers and plastics, automotive materials, electronics, 3D-printed materials, cement and building materials.</li><li><strong>Additional applications:</strong> Art restoration, contamination analysis in cosmetics and personal care products, oil and gas, volcanology and mineralogy, and homeland security.&nbsp;</li></ul><h4><span><strong>Integration with FTIR Spectrometers</strong></span></h4><p>The Nicolet RaptIR + FTIR Microscope can be connected to the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products?category=222&amp;manufacturerItems=3&amp;search=is50"><strong>Thermo Scientific™ Nicolet™ iS50 FTIR Spectrometer</strong></a>. The Nicolet iS50 system provides capabilities ranging from far-IR to visible spectroscopy and can support TGA-IR, FT-Raman, near-infrared and GC-IR applications.</p><p>The microscope can also be used with the more compact <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2452"><strong>Thermo Scientific™ Nicolet™ Apex FTIR Spectrometer</strong></a> or the<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2364"><strong> Thermo Scientific™ Nicolet™ iS20 FTIR Spectrometer</strong></a>.</p><h4><span><strong>Technical Specifications</strong></span></h4><ul><li><strong>Visible spatial resolution:</strong> 1 µm.</li><li><strong>Infrared spatial resolution:</strong> 5 µm.</li><li><strong>Camera:</strong> 5 megapixels.</li><li><strong>Visible objectives:</strong> 4× or 40×.</li><li><strong>Infrared objectives:</strong> 15× or grazing-angle infrared objective.</li><li><strong>Mapping rate:</strong> Up to 10 spectra per second.</li><li><strong>Maximum sample thickness:</strong> 40 mm.</li><li><strong>Maximum sample mass:</strong> 5 kg.</li><li><strong>Detector options:</strong> User-swappable MCT-A, MCT-B and InGaAs.</li><li><strong>Polarizers:</strong> Motorized visible and infrared polarizers.</li></ul>

Products from category Microscopy from Thermo Fisher Scientific - page 1

Related content

Reducing Errors and Increasing Throughput in ICP-MS and ICP-OES with Automated Dilution

Webinars LabRulezICPMS Week 45/2026

Nutrient imbalances caused by industrial pollution were not affected by extreme climate events