International team of scientists shed light on the processes that drive the global distribution of air pollutants - the re-emission of polycyclic aromatic compounds (PACs). The new study was published in the Journal of Hazardous Materials.PACs are long-lived toxic substances contributing significantly to air pollution in the industrialized world. They are inevitable byproducts of all kinds of fossil fuel and wood combustion, and following dry or wet deposition (rainfall), PACs are transferred to and stored in soils. In response to continued pollution and wind conditions for transport and deposition, PACs may volatilize from the soil surface and be re-released into the air. That way, soils become secondary sources of these air pollutants.By determining air and soil contamination as well as the exchange between air and soil in rural grassland and in a remote forest, the scientists identified a number of substances being potentially re-emitted.“Such re-emissions might add significantly to the concentrations of PACs in ambient air far from source areas," emphasizes the importance of these findings Gerhard Lammel from the RECETOX center.For the first time, they also quantified the soil’s re-emission flux (mass of PACs volatilised per time and area) in a boreal forest in Finland. When extrapolating this flux to the country scale, they found it comparable to the primary emissions from industry, household heating, and motor vehicle traffic in Finland. The results of the study, published in the Journal of Hazardous Materials, suggest that such secondary emissions in countries receiving air pollution from neighboring states might even exceed the domestic primary emissions."Our results suggest that emission inventories at least in the less populated countries of Europe should account for this additional type of sources. We need more measurements to help identify sensitivities towards certain soil conditions driving these re-emissions to ultimately arrive at more accurate emission inventories across landscapes,” adds Lammel.Furthermore, the research highlights the 'grasshopper effect’, meaning that the potential of re-emission enhances the widespread distribution and environmental lifetimes of substances hazardous for human health and ecosystems.<blockquote>The research was supported by the Czech Science Foundation (25-17534S); Research Infrastructure ACTRIS-CZ (No. LM2023030) and RECETOX (No. LM2023069) financed by the Ministry of Education, Youth and Sports, and the OP RDE (the CETOCOEN EXCELLENCE project No. CZ.02.1.01/0.0/0.0/17_043/0009632).</blockquote><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/RECETOX_MUNI_Studie_odhalila_necekane_velky_prinos_pudy_ke_znecisteni_ovzdusi_0c2b62ee68.jpg" alt="RECETOX-MUNI: Study reveals an unexpectedly large contribution to air pollution from soils" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_RECETOX_MUNI_Studie_odhalila_necekane_velky_prinos_pudy_ke_znecisteni_ovzdusi_0c2b62ee68.jpg 146w," sizes="100vw" width="738" height="790"><blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S0304389426022636?via%3Dihub#sec0005">Polycyclic aromatic compounds in air – importance of re-volatilisation from soils</a></h4>Gerhard Lammel, Dominika Bezdeková, Jakub Martiník, Karsten Baumann, Rostislav Červenka, Petr Kukučka, Ondřej Letocha, Ludovic Mayer, Petra Přibylová, Roman Prokeš, Üllar Rannick, Risto TaipaleJ. Hazard. Mater., 2026, 516, 143283&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.jhazmat.2026.143283">https://doi.org/10.1016/j.jhazmat.2026.143283</a><h6>licenced under<a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by-nc/4.0/"> CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>Polycyclic aromatic hydrocarbons (PAHs) and their nitrated and oxygenated derivatives (NPAHs, OPAHs) are semivolatile air pollutants which may re-volatilise following atmospheric deposition to soil. Here, we determined polycyclic aromatic compounds’ (PACs) concentrations in air, topsoil and air equilibrated with soil at a rural grassland site and a boreal forest site. The samples were analysed by GC-MS/MS and the flux was studied by fugacity calculations and a micrometeorological flux-gradient method. In soil at the boreal site, OPAH and NPAH contributed much higher fractions to PAC contamination of air and soil than at the rural site, reflecting the conversion of primary PACs during transport from sources. The same number of PACs in soil have reached equilibrium concentration with air, despite one site being in a polluted and PAC source region and the other in a much less polluted and PAC receptor region. The direction of air-soil exchange was found insensitive to the modest day-night temperature variation at both sites. Upward diffusive flux was observed for one PAH, triphenylene, at the rural grassland site, and for three 3-ring PAHs and naphthaldehyde at the boreal forest site. There, emission fluxes were quantified and ranged 0.5–12 ng m−2 h−1. The results indicate that low molecular weight PAH secondary emissions in a receptor region may be of same order of magnitude as domestic primary emissions.

Study reveals an unexpectedly large contribution to air pollution from soils

Whether a drug can effectively bind to its target protein, or how different parts of a virus or a cell interact, depends on processes taking place at the level of individual molecules. Their behaviour is determined not only by their shape, but also by the electrostatic forces acting between them. Understanding how these forces are distributed helps scientists explain why certain molecules attract each other, how they bind and how they interact.This is where the <a target="_blank" rel="noopener noreferrer" href="https://acc.biodata.ceitec.cz/">Atomic Charge Calculator (ACC)</a> comes in. Researchers at Masaryk University have been developing this computational tool for more than a decade. Its third and most advanced generation to date was developed at CEITEC Masaryk University and the Faculty of Science at Masaryk University, in collaboration with the Faculty of Informatics at Masaryk University and Palacký University Olomouc.ACC III calculates the electric charges of individual atoms and visualises their distribution directly within three-dimensional molecular structures. It brings together twenty different calculation methods in a single environment and can work with a wide range of molecules – from small organic compounds to proteins and other large biomolecular structures.A key advantage of Atomic Charge Calculator III is that it combines a broad range of computational methods with ease of access. Basic calculations can be performed directly in a web browser, with no need to install specialised software or register for an account. The resulting charges can be displayed directly on a 3D model of the molecule. For advanced users and large-scale analyses, the platform also supports automated data processing and allows its computational core to be run locally.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Co_pritahuje_molekuly_Nova_generace_nastroje_z_CEITEC_zviditelnuje_sily_mezi_atomy_d32d7bd2cd.jpg" alt="CEITEC/Biological Data Management and Analysis Core Facility: What Attracts Molecules? A New Generation of a CEITEC Tool Makes the Forces Between Atoms Visible: Oseltamivir bound to influenza virus neuraminidase (blue: positive partial charges, red: negative charges). A strong electrostatic interaction occurs between a negatively charged region of the drug and positively charged regions of the protein." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Co_pritahuje_molekuly_Nova_generace_nastroje_z_CEITEC_zviditelnuje_sily_mezi_atomy_d32d7bd2cd.jpg 140w," sizes="100vw" width="1600" height="1786"><h3>Why are scientists interested in the electric charges of atoms?</h3>Electrons are not distributed evenly within molecules. Individual atoms can therefore carry different partial electric charges. These charges play an important role in determining how molecules behave towards their surroundings and towards one another.Positively and negatively charged regions of molecules can attract each other, while regions with the same charge repel each other. The distribution of these charges therefore helps determine which molecules approach each other, how they orient themselves and how strongly they may bind. In biology, this is important, for example, in molecular recognition or when a drug binds to its target protein. Understanding partial charges therefore helps scientists gain insight into the interactions underlying the behaviour of many molecular systems.There is, however, no single universal way to determine partial charges. Different computational methods can produce different values, and the choice of method also depends on how the results will be used. Accurate quantum-chemical calculations can also become very computationally demanding when large numbers of structures are involved. ACC III therefore brings together empirical methods that allow these calculations to be performed more quickly and on a large scale.“From the outset, we designed ACC III to make calculating partial atomic charges as straightforward as possible. Users do not need to install anything or deal with complicated settings – they simply upload a molecule and start the calculation with a single click. The application then suggests suitable methods from the twenty available and can handle both small molecules and large biomolecular structures,” says <a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.eu/tomas-racek-ph-d/u94476?page=publication">Tomáš Raček</a>, who has been developing and maintaining ACC since 2018.<h3>How an antiviral drug binds to an influenza virus protein</h3>The authors demonstrate what charge distribution can reveal using the well-known antiviral drug oseltamivir, marketed as Tamiflu. The drug binds to neuraminidase, a protein of the influenza A virus. ACC III can show directly within the three-dimensional structure where positive and negative partial charges are located and how they contribute to the interaction between the drug and the protein.“The example of oseltamivir clearly shows why it is useful not only to calculate the charges, but also to visualise them directly within the structure. This allows us to see which parts of the two molecules interact electrostatically. The same approach can be used to study many other molecular systems,” explains Tomáš Raček.ACC III is not limited to small molecules. It can also work with proteins and other large biomolecular structures. The authors demonstrate this using a second example: the SARS-CoV-2 pore complex. Coronaviruses form these pores during replication in infected cells and use them to transport viral RNA across membranes. Visualising partial charges helps distinguish the parts of the complex that pass through the non-polar environment of the membrane from its more highly charged regions.<h3>From calculation straight to a 3D model</h3>The new generation of the Atomic Charge Calculator also offers more advanced visualisation. It uses Mol*, which allows calculated charges to be mapped directly onto a three-dimensional structure and explored interactively. A visualisation created using ACC III was also selected for the cover of the special Nucleic Acids Research Web Server Issue. Created by Tomáš Raček, the cover image shows the distribution of partial charges in a membrane protein system.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Co_pritahuje_molekuly_Nova_generace_nastroje_z_CEITEC_zviditelnuje_sily_mezi_atomy_3_85cc310925.jpeg" alt="CEITEC/Oxford University Press: What Attracts Molecules? A New Generation of a CEITEC Tool Makes the Forces Between Atoms Visible: Cover page in Nucleic Acids Research journal." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Co_pritahuje_molekuly_Nova_generace_nastroje_z_CEITEC_zviditelnuje_sily_mezi_atomy_3_85cc310925.jpeg 124w," sizes="100vw" width="1600" height="2011">Results can be downloaded in several standard formats and, for the first time, stored directly in the mmCIF format commonly used for three-dimensional biomolecular structures. Information about the structure and its calculated charges can therefore remain together in a single file and be used by other tools.For researchers who need to process large numbers of structures, ACC III also provides an API and a computational core that can be run locally. The platform can therefore be used both for individual calculations through its web interface and as part of larger automated analyses.<h3>More than a decade of development</h3>Scientists introduced the first Atomic Charge Calculator in 2015, followed by its second generation in 2020. In the meantime, the team also developed specialised tools: PDBCharges for structures from the Protein Data Bank and AlphaCharges for structures from the AlphaFold Database.“The Atomic Charge Calculator was never a one-off project,” says <a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.eu/prof-radka-svobodova-ph-d/u17518?page=publication">Radka Svobodová</a>, Head of the Biological Data Management and Analysis Core Facility at CEITEC Masaryk University. “For more than a decade, we have been continuously developing tools that respond both to new possibilities in structural bioinformatics and to the needs of their users. The third generation combines straightforward web-based use with capabilities that are important for the automated processing of large numbers of molecular structures.”<blockquote>Atomic Charge Calculator III is freely available through its web interface and does not require registration for basic use. Its development was supported by the ELIXIR CZ research infrastructure.</blockquote><h5>The authors presented the new generation of the tool in <a target="_blank" rel="noopener noreferrer" href="https://academic.oup.com/nar/article/54/W1/W211/8662890">Nucleic Acids Research</a>.</h5>

What Attracts Molecules? A New Generation of a CEITEC Tool Makes the Forces Between Atoms Visible 

Not every concentration job can tolerate heat — and not every concentrator that handles heat well can handle cold. <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2441">Refrigerated centrifugal vacuum concentrators</a> exist for a specific reason: proteins, RNA, enzymes, and synthetic peptides degrade quickly under thermal stress, and standard concentrators that rely on heat alone can compromise sample integrity before evaporation finishes. We compared two of the leading refrigerated systems — the Labconco Refrigerated CentriVap and the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2611">Thermo Fisher Refrigerated SpeedVac SRF110</a> — to see how they stack up for labs where sample preservation is non-negotiable.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://explore.organomation.com/labconco-refrigerated-centrivap-vs-thermo-fisher-refrigerated-speedvac">Download the full comparison with pricing here!</a></blockquote><h3>The Problem Refrigeration Actually Solves</h3>It's a detail that gets lost in most spec-sheet comparisons: running a<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/lcms/products?manufacturerItems=540&amp;search=centrivap"> vacuum concentrator </a>without temperature control can cause a sample to over-cool itself. As solvent evaporates under vacuum, the process pulls latent heat from the sample — the same evaporative cooling effect that makes sweat feel cold on skin. For a heat-stable solvent, that's irrelevant. For a temperature-sensitive biomolecule, it can drop the sample low enough to risk unwanted freezing or sublimation mid-run. Labconco's own engineering notes for the Refrigerated CentriVap describe this directly: the unit pairs a refrigeration system with a heater so operators can hold a precise set-point temperature and avoid sublimated samples caused by evaporative cooling. That's the whole reason this product category exists, and it's worth understanding before comparing specs line by line.<h3>Price: A Wider Gap at the High End</h3>The Labconco Refrigerated CentriVap is typically priced around $13,000 USD. The Thermo Fisher SRF110 runs higher, generally $15,000–$17,000 USD, and that's before factoring in the modular kit components — Thermo Fisher sells the SRF110 with a separate vacuum system, rotor, vapor trap, and heat transfer fluid bundled into the total kit price. The price gap between these two refrigerated units is proportionally larger than what we found comparing their non-refrigerated counterparts, which makes the value case for the CentriVap even more pronounced at this tier.<h3>Capacity: The Difference That Matters Most Right Now</h3>This is where the two systems really separate, and it lines up with where lab demand is heading. The Refrigerated CentriVap processes up to 312 samples per run; the SRF110 tops out at 132. Both handle volumes up to 50 mL, so this isn't a volume trade-off the way it was in our earlier comparison — it's a straight throughput advantage for the CentriVap.That gap matters because<a target="_blank" rel="noopener noreferrer" href="https://peptidestaff.com/industry-trends/peptide-therapy-market-forecast-2026/"> peptide-based therapeutics </a>have become one of the fastest-growing classes of drugs in the pharmaceutical industry, and manufacturing capacity — not demand — is widely cited as the primary bottleneck holding the sector back. <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7541">GLP-1 programs</a> in particular are pushing <a target="_blank" rel="noopener noreferrer" href="https://www.bachem.com/knowledge-center/glp-1-demand-for-peptide-manufacturers/">peptide manufacturers</a> toward industrialized, large-scale production platforms rather than one-off batch work. <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/">Sample prep equipment</a> sits squarely inside that bottleneck: every purification run, HPLC fraction, and concentration step has to scale alongside the chemistry. A concentrator that processes more than double the samples per run, like the Refrigerated CentriVap, is a meaningfully different proposition for a peptide synthesis or purification lab than it would have been five years ago.<h3>Temperature Range: How Cold You Can Go</h3>The CentriVap's refrigeration reaches as low as -10°C; the SRF110 bottoms out at -4°C. Both units heat up to +100°C. That six-degree gap on the cold end isn't dramatic on paper, but for the most heat-labile peptides and enzymes, the lower floor gives operators more margin before a sample is at risk — particularly during longer runs where evaporative cooling has more time to compound any thermal load on the sample.<h3>Vortex Speed and Mechanical Flexibility</h3>The CentriVap offers an adjustable vortex range from 500 to 1,800 rpm, while the SRF110 runs up to 1,725 rpm. The CentriVap's lower floor is the more useful distinction here — fragile, large, or shear-sensitive samples (think intact proteins or larger peptide constructs) sometimes need to run at reduced rotor speed to avoid mechanical stress, and the CentriVap gives operators that headroom on both ends rather than just a ceiling.<h3>Lid Material: Visibility vs. Durability</h3>The Refrigerated CentriVap uses a glass lid, letting operators see into the chamber during a run. The SRF110 uses an epoxy-coated aluminum lid, which trades visibility for added durability. For labs running visually distinct sample batches — colored buffers, multiple project codes, HPLC fractions pulled at different time points — the ability to glance at the chamber without interrupting a run has real workflow value, especially in a core facility setting where one instrument serves multiple research groups.<h3>What This Means for Core Facilities</h3>Shared instrumentation cores feel throughput and cold-temperature constraints differently than a single-PI lab does. A<a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/an-appreciation-for-academic-core-labs"> core running samples from multiple research groups </a>— some doing routine RNA cleanup, others running heat-labile peptide fractions from an HPLC purification step — needs an instrument that won't bottleneck on either axis. The CentriVap's combination of higher per-run capacity and a lower refrigeration floor gives a shared facility more room to serve mixed workloads without forcing every group onto the same conservative settings a less flexible unit would require.<h3>Built for the Same Footprint</h3>Both units are sized for fume hood placement, with the CentriVap measuring 15.0 x 27.2 x 13.9 inches against the SRF110's 16.62 x 25 x 13.75 inches — close enough that floor planning isn't a deciding factor either way. Both carry standard one-year warranties.<h3>The Bottom Line</h3>For labs concentrating proteins, RNA, enzymes, or peptide fractions at scale — particularly anyone supporting peptide therapeutic development, where production capacity is already the limiting factor industry-wide — the Labconco Refrigerated CentriVap's combination of higher throughput, lower cold-temperature floor, and lower price makes it the stronger fit. The SRF110 remains a capable option for labs with smaller batch sizes already standardized on Thermo Fisher's modular vacuum ecosystem.Organomation distributes the full Labconco CentriVap line, including the Refrigerated and Refrigerated Pro models. Contact our team at sales@organomation.com to talk through rotor configuration, cold trap pairing, and throughput planning for your lab.&nbsp;<blockquote><h5><a target="_blank" rel="noopener noreferrer" href="https://explore.organomation.com/labconco-refrigerated-centrivap-vs-thermo-fisher-refrigerated-speedvac">Download the full comparison with pricing here!</a></h5></blockquote>

Refrigerated SpeedVac SRF110 vs. CentriVap - Why Sample Capacity Matters More Than Ever for Peptide and Protein Labs

Article

Product

Environment

Science and research

RECETOX (Research Centre for Toxic Compounds in the Environment) is an independent department of the Faculty of Science of Masaryk University in Brno, which has been established in 1983. RECETOX is focused on the research and education in cross-cutting area of Environment and Health. It addresses interactions among chemicals, environment, and biological systems, including consequences at local, regional, and global levels.

RECETOX - Centrum pro výzkum toxických látek v prostředí

Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

CEITEC

Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

Organomation

Thermo Scientific™ Q Exactive™ GC Orbitrap GC-MS/MS System

High-resolution GC-MS system combining Orbitrap accuracy with full-scan sensitivity and MS/MS power for confident quantitation and compound identification in complex matrices.

<h4>Next-generation high-resolution GC-MS for confident quantitation and unknown identification</h4>The Q Exactive GC Orbitrap GC-MS/MS system is the first commercial benchtop system to combine gas chromatography with Orbitrap™ high-resolution accurate-mass (HRAM) detection. It offers unrivaled resolving power, sub-ppm mass accuracy, and the quantitation power of triple quadrupole systems — all in untargeted full-scan mode.Designed for food safety, metabolomics, environmental, clinical, and pharmaceutical labs, this hybrid quadrupole-Orbitrap system brings unmatched performance for both discovery and targeted workflows, with robust EI/CI ionization, smart deconvolution, and intuitive software.<h3>Key Benefits</h3><h4>🎯 High-resolution power for confident detection</h4><ul><li>Up to 100,000 resolution (FWHM) at m/z 272</li><li>Sub-1 ppm mass accuracy (internal) in routine full-scan MS</li><li>Accurate detection even in part-per-trillion range</li><li>Resolves coeluting peaks in complex matrices with ease</li></ul><h4>💡 Unmatched qualitative and quantitative versatility</h4><ul><li>EI, PCI, NCI ionization with ExtractaBrite™ source (removable under vacuum)</li><li>Full-scan sensitivity equal to SRM mode of triple quadrupoles</li><li>PRM and MS/MS with HCD collision cell</li><li>Variable electron voltage (VeV) for softer EI and improved identification</li></ul><h4>🧠 Advanced tools for unknown identification</h4><ul><li>Deconvolution software with HRAM fragment interpretation</li><li>Compatibility with NIST/Wiley libraries and HRAM spectral libraries</li><li>Supports <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/77">TraceFinder™</a>, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1759">Compound Discoverer™</a>, and<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1757"> Mass Frontier™</a></li></ul><h3>System Capabilities</h3><ul><li>Mass range: 30–3000 m/z</li><li>Mass accuracy: &lt;1 ppm RMS (internal), &lt;3 ppm RMS (external)</li><li>Quantitative dynamic range: &gt;10⁶</li><li>In-spectrum dynamic range: &gt;5000:1</li><li>Scan speed: up to 18 Hz @ 12,500 resolution</li><li>Simultaneous detection of up to 10 precursors per scan</li></ul><h3>Operation &amp; Workflow</h3><ul><li>Full MS, SIM, Timed SIM, PRM, polarity switching, DDA</li><li>Automatic gain control (AGC) ensures optimal ion population in Orbitrap</li><li>Easy maintenance with vent-free source and column exchange</li><li>Seamless <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1758">Xcalibur™</a> and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/77">TraceFinder™</a> control with automated tuning/calibration</li></ul><h3>Sample Introduction &amp; Automation</h3><ul><li>Compatible with TRACE™ 1310 GC with Instant Connect injectors</li><li>Autosamplers: TriPlus RSH for full automation and microsample workflows</li><li>Direct probes (DEP/DIP) for solid/liquid samples — no venting required</li></ul><h3>Applications</h3><ul><li>Food safety &amp; authenticity (pesticides, packaging migration)</li><li>Metabolomics, environmental &amp; clinical toxicology</li><li>Extractables &amp; leachables, forensics, pharmaceuticals</li><li>Untargeted and targeted multi-analyte screening</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/application::product.product/QExactive-GCMSMS-Orbitrap-with-Autosampler-Front-1858x1391.jpg-650.jpg" alt="Thermo Scientific™ Q Exactive™ GC Orbitrap GC-MS/MS System" width="null" height="null">

Thermo Scientific™ Exactive™ GC Orbitrap™ GC-MS System

High-resolution Orbitrap GC-MS system for confident quantitation and unknown screening. Delivers sub-ppb sensitivity, <1 ppm accuracy, and routine full-scan workflows.

<h4>Bringing high-resolution Orbitrap technology into routine GC-MS workflows</h4>The Exactive GC Orbitrap system offers the unmatched mass accuracy, resolving power, and sensitivity of Orbitrap technology in a platform optimized for routine applications. This high-performance GC-MS system enables both targeted and non-targeted full-scan workflows with confident quantitation and trace-level detection, even in complex matrices. Designed for maximum robustness and usability, it streamlines operations across food safety, environmental, industrial, forensic, and anti-doping laboratories.<h3>Key Features and Benefits</h3><h4>💡 Unmatched HRAM Performance</h4><ul><li>Resolving power up to 60,000 FWHM at m/z 200</li><li>Mass accuracy: &lt;1 ppm (internal), &lt;3 ppm (external)</li><li>Quantitative dynamic range: &gt;10⁶, with excellent linearity and precision</li><li>Routine IDLs in the sub-ppb to ppt range</li></ul><h4>🧪 Full-Scan Sensitivity and Selectivity</h4><ul><li>Combines triple-quad-like quantitation with full-scan Orbitrap capability</li><li>Sub-ppb sensitivity for 100+ pesticides in food matrices</li><li>High selectivity and confidence in trace-level compound identification</li><li>Spectral deconvolution with accurate-mass fragment filtering</li></ul><h4>⚙️ Proven Orbitrap Design</h4><ul><li>Curved linear trap (C-Trap) and bent flatapole ion optics</li><li>ExtractaBrite™ ion source (EI/PCI/NCI) – removable under vacuum</li><li>Vent-free column exchange using patented source plug</li><li>Optional direct sample probes (DIP, DEP) for solid or thermolabile analytes</li></ul><h4>🧠 Streamlined Software and Data Processing</h4><ul><li>Controlled by <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/77">TraceFinder™</a> and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1758">Xcalibur™</a> platforms</li><li>Full-scan acquisition with automated data mining</li><li>Integrated spectral libraries (NIST, Thermo Food/Environmental)</li><li>Spectral fidelity and mass accuracy retained across wide concentration range</li></ul><h4>🔁 Optimized GC Integration</h4><ul><li>Built on the TRACE™ 1310 GC platform</li><li>Supports all injection/detection configurations (SSL, PTV, backflush, etc.)</li><li>Paired with TriPlus™ RSH autosampler for advanced robotic sample handling</li><li>Excellent retention time stability and fast oven cycling</li></ul><h3>Ideal For Applications In:</h3><ul><li>Food safety and authenticity (pesticide screening, additives)</li><li>Environmental analysis (contaminants, pollutants, air toxics)</li><li>Forensics and toxicology (unknowns, drugs, metabolites)</li><li>Industrial QC (extractables, volatiles, impurity profiling)</li><li>Non-targeted screening with full-scan HRAM and retrospective analysis</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/application::product.product/exactive-gc-orbitrap-gc-ms-front-2000x2000.jpg-650.jpg" alt="Thermo Scientific™ Exactive™ GC Orbitrap™ GC-MS System" width="null" height="null">

Thermo Scientific™ ISQ™ 7000 Single Quadrupole GC-MS System

Robust single quad GC-MS with advanced ion sources, NeverVent™ tech, SmartTune, and flexible software. Delivers sensitive, high-throughput routine analysis.

<h4>Unstoppable GC-MS performance for routine, regulatory, and high-throughput analysis</h4>The ISQ 7000 GC-MS system delivers reliable, scalable, and ultra-sensitive performance for routine analysis in food safety, environmental, clinical, and forensic laboratories. Designed to maximize uptime and analytical confidence, it features advanced ion source options, easy maintenance with NeverVent™ technology, and intuitive software tools like SmartTune and AutoSIM.<h3>Key Features and Benefits</h3><h4>🚀 Unstoppable Sensitivity</h4><ul><li>Advanced Electron Ionization (AEI) source for femtogram-level detection</li><li>Robust ExtractaBrite™ ion source, fully removable under vacuum</li><li>Dual-filament design and S-shaped ion optics reduce neutral and chemical noise</li><li>Simultaneous full-scan and SIM acquisition modes</li></ul><h4>⚙️ Unstoppable Uptime</h4><ul><li>NeverVent™ technology with Vacuum Probe Interlock (VPI) and V-Lock for maintenance without venting</li><li>Heated ion optics and RF lens protect quadrupole from matrix contamination</li><li>Reliable quadrupole design: solid, non-coated rods and maintenance-free performance</li><li>Up to 98% downtime reduction for routine interventions (e.g. source cleaning)</li></ul><h4>🧠 Smart Automation and Ease of Use</h4><ul><li>SmartTune for guided, fast, and consistent system tuning</li><li>AutoSIM and Timed-SIM (t-SIM) for efficient method creation</li><li>Retention Time Alignment (RTA) tool for consistent results across column changes</li><li>Deconvolution tools for untargeted compound identification</li></ul><h4>🧪 Flexible Analytical Capabilities</h4><ul><li>EI, PCI, NCI ionization modes (with optional dual reagent gas switching)</li><li>Mass range: 1.2–1100 u; scanning speed up to 240 scans/s</li><li>Optional Direct Insertion and Direct Exposure probes for solid samples</li><li>Software-switchable ionization modes in a single analysis</li></ul><h4>🖥️ Integrated Software and Data Handling</h4><ul><li>Full control via <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/76">Chromeleon™ CDS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/77">TraceFinder™</a></li><li>Preloaded application libraries and eWorkflows (e.g. US EPA, clinical, toxicology)</li><li>Auto-calibration, QA/QC tools, and compliance-ready (21 CFR Part 11)</li><li>Seamless LIMS connectivity and user-guided reporting tools</li></ul><h4>🔁 Sample Introduction Options</h4><ul><li>Compatible with AI/AS 1310, TriPlus 300 (HS), and TriPlus RSH autosamplers</li><li>Robotic workflows including dilution, standard addition, and derivatization</li><li>Ideal for trace analysis in complex matrices and high-throughput environments</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/application::product.product/isq-7000-trace-1310-triplus-rsh-left-1200x1200.jpg-650_s.webp" alt="Thermo Scientific™ ISQ™ 7000 Single Quadrupole GC-MS System" width="382" height="382">

Thermo Scientific™ TSQ™ 9000 GC-MS/MS System

Triple quadrupole GC-MS/MS system offering exceptional sensitivity, robustness, and smart automation for trace-level quantitation in food, environmental, and forensic analysis.

High-performance triple quadrupole GC-MS/MS platform for routine trace-level quantitation in complex matricesThe TSQ™ 9000 GC-MS/MS system is built for laboratories that demand uncompromising sensitivity, throughput, and robustness for trace-level analysis in food safety, environmental, and forensic/toxicology applications. Designed to increase productivity and reduce cost-per-sample, this system delivers best-in-class performance with intuitive tools for routine and advanced users alike.<h3>Key features and benefits</h3><h4>🚀 Unstoppable Sensitivity</h4><ul><li>Advanced Electron Ionization (AEI) source for attogram-level sensitivity, ideal for demanding applications like dioxins and pesticides in baby food.</li><li>ExtractaBrite™ ion source: robust EI/CI performance, proven in routine use; fully removable under vacuum with NeverVent™.</li><li>Ionization modes: EI, PCI, NCI (CI available with ExtractaBrite only)</li></ul><h4>🔬 Unstoppable Performance</h4><ul><li>EvoCell™ collision cell: up to 800 SRM transitions/s with excellent precision</li><li>0.5 ms minimum dwell time; up to 97 scans/s; 20,000 u/s quadrupole scan speed</li><li>Mass range: 1.2–1100 u, unit mass resolution</li><li>Mass stability: &lt;0.1 u over 48 h</li></ul><h4>🔧 Unstoppable Uptime</h4><ul><li>NeverVent™ technology (with VPI &amp; ExtractaBrite): perform maintenance or column changes without venting</li><li>V-Lock column isolation prevents system venting during GC maintenance</li><li>Dual heated source lenses for minimal contamination and high matrix tolerance</li></ul><h3>Ease of Use and Intelligent Method Development</h3><ul><li>AutoSRM™: Automated SRM development wizard</li><li>SIM Bridge™: Convert legacy SIM methods into SRM in seconds</li><li>Timed-SRM and Retention Time Alignment (RTA): Maintain optimal sensitivity and peak tracking across injections</li><li>SmartTune™: Intuitive system tuning with error guidance</li></ul><h3>Software Platforms</h3><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76">Chromeleon™ CDS</a></h4><ul><li>Fully integrated control of chromatography and mass spectrometry</li><li>One-click eWorkflows™, Intelligent Run Control, automated compliance tools</li><li>Environmental Analysis Extension Pack for U.S. EPA workflows</li></ul><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/77">TraceFinder™</a></h4><ul><li>Comprehensive solution for method development, acquisition, processing, and reporting</li><li>Preloaded SRM database for over 1300 pesticides (environmental/food safety versions)</li><li>Application-specific variants for clinical research, toxicology, and environmental labs</li></ul><h3>System Specifications</h3><ul><li>Ion sources: AEI and ExtractaBrite (CI optional)</li><li>Transfer line temperature: up to 400 °C</li><li>Detector: DynaMax™ XR system with off-axis dynode and wide dynamic range (&gt;10⁷)</li><li>Mass resolution: Adjustable 0.4–2.5 u, preset or manual</li><li>Pumping system: High-capacity turbomolecular with rotary vane or optional oil-free scroll</li><li>Direct Probe Options (VPI only): DIP and DEP probes for solid and rapid samples</li></ul><h3>Sample Introduction Options</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/68">AI/AS 1310 Autosampler</a>: high-precision injections, advanced rinse protocols</li><li>TriPlus™ RSH Autosampler: robotic automation including dilution, internal standard addition, derivatization, and tool switching</li></ul><h3>System Dimensions and Compatibility</h3><ul><li>Fully compatible with Thermo Scientific™ TRACE™ 1300/1310 GC</li><li>Mass spectrometer: 44 × 40 × 89 cm; 61 kg</li><li>Modular design enables scalable performance and easy upgrades</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/application::product.product/Thermo-TSQtm-9000-1310-triplus-rsh_l.webp" alt="Thermo Scientific™ TSQ™ 9000 GC-MS/MS System" width="708" height="708">

Thermo Scientific™ Prima BT Bench Top Process Mass Spectrometer

Achieve high scanning speeds and reproducible measurements with the Thermo Scientific™ Prima BT Bench Top Mass Spectrometer.

<div><div>Achieve high scanning speeds and reproducible measurements with the Thermo Scientific™ Prima BT Bench Top Process Mass Spectrometer. Specifically designed for process development laboratories, this real-time process gas analyzer is a highly precise, multi-port magnetic sector analyzer.</div><div>The Prima BT Process Mass Spectrometer offers robust performance in the presence of off-gases and vapors that have the potential to contaminate internal vacuum components. As the ions are extracted from the ion source at high energy, excellent stability is achieved for low molecular weight compounds such as hydrogen and helium.<h4>✔️ Key Features</h4><ul><li>Scanning magnetic-sector technology</li><li>16-port Rapid Multistream Sampler (RMS)</li><li>Six-port automatic calibration manifold</li><li>High analytical precision, accuracy and stability</li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/pharma-biopharma/manufacturing-control-pharma-biopharma/process-analytical-technology/gasworks-process-analysis-software.html">Thermo Scientific™ GasWorks Software</a></li></ul><h4>Warranty and Service Offering</h4>To maintain optimal product performance, you need immediate access to experts worldwide, as well as priority status when your analyzer needs repair or replacement. We offer comprehensive, flexible support solutions for all phases of the product life cycle. Through predictable, fixed-cost pricing, our services help protect the return on investment and total cost of ownership of your Thermo Scientific products.</div><div>The Thermo Scientific Prima BT Bench top Mass Spectrometer is an industrial laboratory gas analyzer based on scanning magnetic-sector mass spectrometry. Designed for continuous operation in a laboratory environment, the Prima BT mass spectrometer is simple to operate and easy to maintain.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Prima_BT_procesni_MS_pro_analyzu_plynu_1_b38b34871c/Thermo-Prima-BT-procesni-MS-pro-analyzu-plynu-1.jpg" alt="Thermo Scientific™ Prima BT Bench Top Process Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Prima_BT_procesni_MS_pro_analyzu_plynu_1_b38b34871c/thumbnail_Thermo-Prima-BT-procesni-MS-pro-analyzu-plynu-1.jpg 199w," sizes="100vw" width="927" height="726"><h3>⚙️ Specifications</h3><ul><li>Analysis Time: 0.3 to 1.0 sec. per gas component</li><li>Analyzer Type: Scanning Magnetic Sector Mass Spectrometer with Enclosed Electron Impact Dual Filament Ion Source</li><li>Area Classification Options: General Purpose</li><li>Depth (English): 1.8 ft.</li><li>Depth (Metric): 0.56 m</li><li>Dynamic Range: Faraday: 10 ppm to 100 ppm</li><li>Dynamic Range (optional): Single MCP SEM: 1 ppm to 1000 ppm; Twin MCP SEM: 10 ppb to 1000 ppm</li><li>Height (English): 1.7 ft.</li><li>Height (Metric): 0.53 m</li><li>No. of Calibration Gas Inlets: Up to 6</li><li>No. of Sample Stream Inlets: Up to 15</li><li>Power: 115/230 V, Consumption: 1.5 kVA</li><li>Precision: ≤ 0.1% relative</li><li>Stability: ≤ 1% relative over one week</li><li>Weight (English): 220 lb., Additional floor mounting rotary pump: 66 lb.</li><li>Weight (Metric): 100 kg, Additional floor mounting rotary pump: 30 kg</li><li>Width (English): 2.8 ft.</li><li>Width (Metric): 0.86 m</li><li>Ambient Temperature: 12 °C to 30 °C</li><li>Communication Protocols: Modbus serial RS232/422/485, Siemens 3964R, VGCP and PVGCP</li><li>Mass Range: Adjustable, 1 to 150 amu at 1000 eV ion acceleration voltage, 1 to 200 amu at 750 eV ion acceleration voltage</li><li>Product Type: Prima BT Bench Top Process Gas Analysis Mass Spectrometer</li><li>Unit Size: Each</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Prima_BT_procesni_MS_pro_analyzu_plynu_2_b4a02abf9d/Thermo-Prima-BT-procesni-MS-pro-analyzu-plynu-2.jpg" alt="Thermo Scientific™ Prima BT Bench Top Process Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Prima_BT_procesni_MS_pro_analyzu_plynu_2_b4a02abf9d/thumbnail_Thermo-Prima-BT-procesni-MS-pro-analyzu-plynu-2.jpg 166w," sizes="100vw" width="1269" height="1189"></div></div>

Products focused on GC/MSD from Thermo Fisher Scientific - page 2

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