High-performance triple quadrupole GC-MS/MS platform for routine trace-level quantitation in complex matrices
The TSQ™ 9000 GC-MS/MS system is built for laboratories that demand uncompromising sensitivity, throughput, and robustness for trace-level analysis in food safety, environmental, and forensic/toxicology applications. Designed to increase productivity and reduce cost-per-sample, this system delivers best-in-class performance with intuitive tools for routine and advanced users alike.
Key features and benefits
🚀 Unstoppable Sensitivity
- Advanced Electron Ionization (AEI) source for attogram-level sensitivity, ideal for demanding applications like dioxins and pesticides in baby food.
- ExtractaBrite™ ion source: robust EI/CI performance, proven in routine use; fully removable under vacuum with NeverVent™.
- Ionization modes: EI, PCI, NCI (CI available with ExtractaBrite only)
🔬 Unstoppable Performance
- EvoCell™ collision cell: up to 800 SRM transitions/s with excellent precision
- 0.5 ms minimum dwell time; up to 97 scans/s; 20,000 u/s quadrupole scan speed
- Mass range: 1.2–1100 u, unit mass resolution
- Mass stability: <0.1 u over 48 h
🔧 Unstoppable Uptime
- NeverVent™ technology (with VPI & ExtractaBrite): perform maintenance or column changes without venting
- V-Lock column isolation prevents system venting during GC maintenance
- Dual heated source lenses for minimal contamination and high matrix tolerance
Ease of Use and Intelligent Method Development
- AutoSRM™: Automated SRM development wizard
- SIM Bridge™: Convert legacy SIM methods into SRM in seconds
- Timed-SRM and Retention Time Alignment (RTA): Maintain optimal sensitivity and peak tracking across injections
- SmartTune™: Intuitive system tuning with error guidance
Software Platforms
Chromeleon™ CDS
- Fully integrated control of chromatography and mass spectrometry
- One-click eWorkflows™, Intelligent Run Control, automated compliance tools
- Environmental Analysis Extension Pack for U.S. EPA workflows
TraceFinder™
- Comprehensive solution for method development, acquisition, processing, and reporting
- Preloaded SRM database for over 1300 pesticides (environmental/food safety versions)
- Application-specific variants for clinical research, toxicology, and environmental labs
System Specifications
- Ion sources: AEI and ExtractaBrite (CI optional)
- Transfer line temperature: up to 400 °C
- Detector: DynaMax™ XR system with off-axis dynode and wide dynamic range (>10⁷)
- Mass resolution: Adjustable 0.4–2.5 u, preset or manual
- Pumping system: High-capacity turbomolecular with rotary vane or optional oil-free scroll
- Direct Probe Options (VPI only): DIP and DEP probes for solid and rapid samples
Sample Introduction Options
- AI/AS 1310 Autosampler: high-precision injections, advanced rinse protocols
- TriPlus™ RSH Autosampler: robotic automation including dilution, internal standard addition, derivatization, and tool switching
System Dimensions and Compatibility
- Fully compatible with Thermo Scientific™ TRACE™ 1300/1310 GC
- Mass spectrometer: 44 × 40 × 89 cm; 61 kg
- Modular design enables scalable performance and easy upgrades
Thermo Scientific™ TSQ™ 9000 GC-MS/MS System
