Whether a drug can effectively bind to its target protein, or how different parts of a virus or a cell interact, depends on processes taking place at the level of individual molecules. Their behaviour is determined not only by their shape, but also by the electrostatic forces acting between them. Understanding how these forces are distributed helps scientists explain why certain molecules attract each other, how they bind and how they interact.This is where the <a target="_blank" rel="noopener noreferrer" href="https://acc.biodata.ceitec.cz/">Atomic Charge Calculator (ACC)</a> comes in. Researchers at Masaryk University have been developing this computational tool for more than a decade. Its third and most advanced generation to date was developed at CEITEC Masaryk University and the Faculty of Science at Masaryk University, in collaboration with the Faculty of Informatics at Masaryk University and Palacký University Olomouc.ACC III calculates the electric charges of individual atoms and visualises their distribution directly within three-dimensional molecular structures. It brings together twenty different calculation methods in a single environment and can work with a wide range of molecules – from small organic compounds to proteins and other large biomolecular structures.A key advantage of Atomic Charge Calculator III is that it combines a broad range of computational methods with ease of access. Basic calculations can be performed directly in a web browser, with no need to install specialised software or register for an account. The resulting charges can be displayed directly on a 3D model of the molecule. For advanced users and large-scale analyses, the platform also supports automated data processing and allows its computational core to be run locally.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Co_pritahuje_molekuly_Nova_generace_nastroje_z_CEITEC_zviditelnuje_sily_mezi_atomy_d32d7bd2cd.jpg" alt="CEITEC/Biological Data Management and Analysis Core Facility: What Attracts Molecules? A New Generation of a CEITEC Tool Makes the Forces Between Atoms Visible: Oseltamivir bound to influenza virus neuraminidase (blue: positive partial charges, red: negative charges). A strong electrostatic interaction occurs between a negatively charged region of the drug and positively charged regions of the protein." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Co_pritahuje_molekuly_Nova_generace_nastroje_z_CEITEC_zviditelnuje_sily_mezi_atomy_d32d7bd2cd.jpg 140w," sizes="100vw" width="1600" height="1786"><h3>Why are scientists interested in the electric charges of atoms?</h3>Electrons are not distributed evenly within molecules. Individual atoms can therefore carry different partial electric charges. These charges play an important role in determining how molecules behave towards their surroundings and towards one another.Positively and negatively charged regions of molecules can attract each other, while regions with the same charge repel each other. The distribution of these charges therefore helps determine which molecules approach each other, how they orient themselves and how strongly they may bind. In biology, this is important, for example, in molecular recognition or when a drug binds to its target protein. Understanding partial charges therefore helps scientists gain insight into the interactions underlying the behaviour of many molecular systems.There is, however, no single universal way to determine partial charges. Different computational methods can produce different values, and the choice of method also depends on how the results will be used. Accurate quantum-chemical calculations can also become very computationally demanding when large numbers of structures are involved. ACC III therefore brings together empirical methods that allow these calculations to be performed more quickly and on a large scale.“From the outset, we designed ACC III to make calculating partial atomic charges as straightforward as possible. Users do not need to install anything or deal with complicated settings – they simply upload a molecule and start the calculation with a single click. The application then suggests suitable methods from the twenty available and can handle both small molecules and large biomolecular structures,” says <a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.eu/tomas-racek-ph-d/u94476?page=publication">Tomáš Raček</a>, who has been developing and maintaining ACC since 2018.<h3>How an antiviral drug binds to an influenza virus protein</h3>The authors demonstrate what charge distribution can reveal using the well-known antiviral drug oseltamivir, marketed as Tamiflu. The drug binds to neuraminidase, a protein of the influenza A virus. ACC III can show directly within the three-dimensional structure where positive and negative partial charges are located and how they contribute to the interaction between the drug and the protein.“The example of oseltamivir clearly shows why it is useful not only to calculate the charges, but also to visualise them directly within the structure. This allows us to see which parts of the two molecules interact electrostatically. The same approach can be used to study many other molecular systems,” explains Tomáš Raček.ACC III is not limited to small molecules. It can also work with proteins and other large biomolecular structures. The authors demonstrate this using a second example: the SARS-CoV-2 pore complex. Coronaviruses form these pores during replication in infected cells and use them to transport viral RNA across membranes. Visualising partial charges helps distinguish the parts of the complex that pass through the non-polar environment of the membrane from its more highly charged regions.<h3>From calculation straight to a 3D model</h3>The new generation of the Atomic Charge Calculator also offers more advanced visualisation. It uses Mol*, which allows calculated charges to be mapped directly onto a three-dimensional structure and explored interactively. A visualisation created using ACC III was also selected for the cover of the special Nucleic Acids Research Web Server Issue. Created by Tomáš Raček, the cover image shows the distribution of partial charges in a membrane protein system.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_Co_pritahuje_molekuly_Nova_generace_nastroje_z_CEITEC_zviditelnuje_sily_mezi_atomy_3_85cc310925.jpeg" alt="CEITEC/Oxford University Press: What Attracts Molecules? A New Generation of a CEITEC Tool Makes the Forces Between Atoms Visible: Cover page in Nucleic Acids Research journal." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_Co_pritahuje_molekuly_Nova_generace_nastroje_z_CEITEC_zviditelnuje_sily_mezi_atomy_3_85cc310925.jpeg 124w," sizes="100vw" width="1600" height="2011">Results can be downloaded in several standard formats and, for the first time, stored directly in the mmCIF format commonly used for three-dimensional biomolecular structures. Information about the structure and its calculated charges can therefore remain together in a single file and be used by other tools.For researchers who need to process large numbers of structures, ACC III also provides an API and a computational core that can be run locally. The platform can therefore be used both for individual calculations through its web interface and as part of larger automated analyses.<h3>More than a decade of development</h3>Scientists introduced the first Atomic Charge Calculator in 2015, followed by its second generation in 2020. In the meantime, the team also developed specialised tools: PDBCharges for structures from the Protein Data Bank and AlphaCharges for structures from the AlphaFold Database.“The Atomic Charge Calculator was never a one-off project,” says <a target="_blank" rel="noopener noreferrer" href="https://www.ceitec.eu/prof-radka-svobodova-ph-d/u17518?page=publication">Radka Svobodová</a>, Head of the Biological Data Management and Analysis Core Facility at CEITEC Masaryk University. “For more than a decade, we have been continuously developing tools that respond both to new possibilities in structural bioinformatics and to the needs of their users. The third generation combines straightforward web-based use with capabilities that are important for the automated processing of large numbers of molecular structures.”<blockquote>Atomic Charge Calculator III is freely available through its web interface and does not require registration for basic use. Its development was supported by the ELIXIR CZ research infrastructure.</blockquote><h5>The authors presented the new generation of the tool in <a target="_blank" rel="noopener noreferrer" href="https://academic.oup.com/nar/article/54/W1/W211/8662890">Nucleic Acids Research</a>.</h5>

What Attracts Molecules? A New Generation of a CEITEC Tool Makes the Forces Between Atoms Visible 

Not every concentration job can tolerate heat — and not every concentrator that handles heat well can handle cold. <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2441">Refrigerated centrifugal vacuum concentrators</a> exist for a specific reason: proteins, RNA, enzymes, and synthetic peptides degrade quickly under thermal stress, and standard concentrators that rely on heat alone can compromise sample integrity before evaporation finishes. We compared two of the leading refrigerated systems — the Labconco Refrigerated CentriVap and the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2611">Thermo Fisher Refrigerated SpeedVac SRF110</a> — to see how they stack up for labs where sample preservation is non-negotiable.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://explore.organomation.com/labconco-refrigerated-centrivap-vs-thermo-fisher-refrigerated-speedvac">Download the full comparison with pricing here!</a></blockquote><h3>The Problem Refrigeration Actually Solves</h3>It's a detail that gets lost in most spec-sheet comparisons: running a<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/lcms/products?manufacturerItems=540&amp;search=centrivap"> vacuum concentrator </a>without temperature control can cause a sample to over-cool itself. As solvent evaporates under vacuum, the process pulls latent heat from the sample — the same evaporative cooling effect that makes sweat feel cold on skin. For a heat-stable solvent, that's irrelevant. For a temperature-sensitive biomolecule, it can drop the sample low enough to risk unwanted freezing or sublimation mid-run. Labconco's own engineering notes for the Refrigerated CentriVap describe this directly: the unit pairs a refrigeration system with a heater so operators can hold a precise set-point temperature and avoid sublimated samples caused by evaporative cooling. That's the whole reason this product category exists, and it's worth understanding before comparing specs line by line.<h3>Price: A Wider Gap at the High End</h3>The Labconco Refrigerated CentriVap is typically priced around $13,000 USD. The Thermo Fisher SRF110 runs higher, generally $15,000–$17,000 USD, and that's before factoring in the modular kit components — Thermo Fisher sells the SRF110 with a separate vacuum system, rotor, vapor trap, and heat transfer fluid bundled into the total kit price. The price gap between these two refrigerated units is proportionally larger than what we found comparing their non-refrigerated counterparts, which makes the value case for the CentriVap even more pronounced at this tier.<h3>Capacity: The Difference That Matters Most Right Now</h3>This is where the two systems really separate, and it lines up with where lab demand is heading. The Refrigerated CentriVap processes up to 312 samples per run; the SRF110 tops out at 132. Both handle volumes up to 50 mL, so this isn't a volume trade-off the way it was in our earlier comparison — it's a straight throughput advantage for the CentriVap.That gap matters because<a target="_blank" rel="noopener noreferrer" href="https://peptidestaff.com/industry-trends/peptide-therapy-market-forecast-2026/"> peptide-based therapeutics </a>have become one of the fastest-growing classes of drugs in the pharmaceutical industry, and manufacturing capacity — not demand — is widely cited as the primary bottleneck holding the sector back. <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7541">GLP-1 programs</a> in particular are pushing <a target="_blank" rel="noopener noreferrer" href="https://www.bachem.com/knowledge-center/glp-1-demand-for-peptide-manufacturers/">peptide manufacturers</a> toward industrialized, large-scale production platforms rather than one-off batch work. <a target="_blank" rel="noopener noreferrer" href="https://www.organomation.com/">Sample prep equipment</a> sits squarely inside that bottleneck: every purification run, HPLC fraction, and concentration step has to scale alongside the chemistry. A concentrator that processes more than double the samples per run, like the Refrigerated CentriVap, is a meaningfully different proposition for a peptide synthesis or purification lab than it would have been five years ago.<h3>Temperature Range: How Cold You Can Go</h3>The CentriVap's refrigeration reaches as low as -10°C; the SRF110 bottoms out at -4°C. Both units heat up to +100°C. That six-degree gap on the cold end isn't dramatic on paper, but for the most heat-labile peptides and enzymes, the lower floor gives operators more margin before a sample is at risk — particularly during longer runs where evaporative cooling has more time to compound any thermal load on the sample.<h3>Vortex Speed and Mechanical Flexibility</h3>The CentriVap offers an adjustable vortex range from 500 to 1,800 rpm, while the SRF110 runs up to 1,725 rpm. The CentriVap's lower floor is the more useful distinction here — fragile, large, or shear-sensitive samples (think intact proteins or larger peptide constructs) sometimes need to run at reduced rotor speed to avoid mechanical stress, and the CentriVap gives operators that headroom on both ends rather than just a ceiling.<h3>Lid Material: Visibility vs. Durability</h3>The Refrigerated CentriVap uses a glass lid, letting operators see into the chamber during a run. The SRF110 uses an epoxy-coated aluminum lid, which trades visibility for added durability. For labs running visually distinct sample batches — colored buffers, multiple project codes, HPLC fractions pulled at different time points — the ability to glance at the chamber without interrupting a run has real workflow value, especially in a core facility setting where one instrument serves multiple research groups.<h3>What This Means for Core Facilities</h3>Shared instrumentation cores feel throughput and cold-temperature constraints differently than a single-PI lab does. A<a target="_blank" rel="noopener noreferrer" href="https://blog.organomation.com/blog/an-appreciation-for-academic-core-labs"> core running samples from multiple research groups </a>— some doing routine RNA cleanup, others running heat-labile peptide fractions from an HPLC purification step — needs an instrument that won't bottleneck on either axis. The CentriVap's combination of higher per-run capacity and a lower refrigeration floor gives a shared facility more room to serve mixed workloads without forcing every group onto the same conservative settings a less flexible unit would require.<h3>Built for the Same Footprint</h3>Both units are sized for fume hood placement, with the CentriVap measuring 15.0 x 27.2 x 13.9 inches against the SRF110's 16.62 x 25 x 13.75 inches — close enough that floor planning isn't a deciding factor either way. Both carry standard one-year warranties.<h3>The Bottom Line</h3>For labs concentrating proteins, RNA, enzymes, or peptide fractions at scale — particularly anyone supporting peptide therapeutic development, where production capacity is already the limiting factor industry-wide — the Labconco Refrigerated CentriVap's combination of higher throughput, lower cold-temperature floor, and lower price makes it the stronger fit. The SRF110 remains a capable option for labs with smaller batch sizes already standardized on Thermo Fisher's modular vacuum ecosystem.Organomation distributes the full Labconco CentriVap line, including the Refrigerated and Refrigerated Pro models. Contact our team at sales@organomation.com to talk through rotor configuration, cold trap pairing, and throughput planning for your lab.&nbsp;<blockquote><h5><a target="_blank" rel="noopener noreferrer" href="https://explore.organomation.com/labconco-refrigerated-centrivap-vs-thermo-fisher-refrigerated-speedvac">Download the full comparison with pricing here!</a></h5></blockquote>

Refrigerated SpeedVac SRF110 vs. CentriVap - Why Sample Capacity Matters More Than Ever for Peptide and Protein Labs

What if you could assess a tumor's metastatic potential — without extensive sample prep — directly from tissue? Rachel Wood is working on exactly that.Rachel Wood is a PhD candidate at Queen's University (Kingston, Ontario),&nbsp;working jointly in the labs of Dr. Richard Oleschuk (Chemistry) and Dr. Chris&nbsp;Nicoll (Pathology &amp; Molecular Medicine). Her research applies Ambient Ionization Mass Spectrometry — specifically the Liquid Microjunction Surface Sampling Probe &nbsp;(LMJ-SSP) and Desorption Electrospray Ionization (DESI) — to profile the metabolomics of non-metastatic and metastatic clear cell Renal Cell Carcinoma (ccRCC) cell lines. The long-term goal: a rapid, minimally invasive MS-based prognostic tool for kidney cancer.This is the first reported use of LMJ-SSP to assess metastatic status in ccRCC —&nbsp;and early PCA results are already showing distinct separation between cell line&nbsp; profiles.<h5>In this episode, David and Rachel cover:</h5><ul><li>Why ccRCC is such a resistant biomarker problem despite active genomic, proteomic, and metabolomic research</li><li>The clinical stakes of "diagnosed by accident" — and what a prognostic biomarker actually needs to do for a clinician</li><li>How AIMS complements (not replaces) LC-MS in a discovery-phase cancer workflow</li><li>LMJ-SSP vs. DESI: what each technique sees that the other misses, including spatial resolution differences (~1mm vs. ~50µm)</li><li>Why Rachel runs LMJ-SSP on both a triple quad and a Q-TOF — and what each instrument contributes to the same research question</li><li>How her lab repurposed a 3D printer as a custom automated XYZ sampling stage with 50µm movement precision</li><li>Managing high-dimensional metabolomics data across two polarities, two cell lines, and two mass analyzers — the pipeline explained</li><li>What unsupervised machine learning (PCA) showed in early results</li><li>The path from cell lines to excised tumor tissue to, ultimately, liquid biopsies</li><li>Advice for analytical chemists considering work at the chemistry–oncology interface</li></ul><h3>Video Transcription</h3>Kidney cancer remains a difficult biomarker problem, particularly when researchers try to distinguish tumors that are likely to behave aggressively from those that are not. In a recent episode of Concentrating on Chromatography, PhD researcher Rachel Wood discussed how she is combining rapid ambient ionization mass spectrometry, LMJ-SSP, DESI, multivariate data analysis, and conventional LC-MS workflows to investigate the molecular differences associated with clear cell renal cell carcinoma and its metastatic potential.<h4>Returning to the research question that started it all</h4>Wood first encountered kidney cancer research during her undergraduate studies. Although she later moved into a more instrumentation-focused master’s project involving breast cancer, the subject of kidney cancer remained unfinished business.When the opportunity arose to choose a PhD project, she returned to the field that had originally sparked her interest in research. She is now conducting her doctoral work at Queen’s University in Kingston, Ontario, in an interdisciplinary environment spanning chemistry, pathology, molecular medicine, computer science, and clinical research.<h4>Why clear cell renal cell carcinoma is such a difficult biomarker problem</h4>Wood’s research focuses on clear cell renal cell carcinoma (ccRCC), which represents the majority of kidney cancer cases discussed in the interview.The difficulty is not a lack of research effort. Genomics, proteomics, and metabolomics studies have all produced promising biomarker candidates. The challenge is that different studies often identify different sets of markers, with relatively little overlap between them.Patient-to-patient biological variability further complicates the picture. A candidate biomarker panel that performs well in one cohort may not reproduce equally well in another. Selecting which features deserve further investigation therefore becomes a major analytical and biological challenge.<h4>From incidental diagnosis to prognostic information</h4>Another difficulty is the way kidney cancer is often discovered.Rather than being detected through a dedicated screening program, tumors may be found incidentally during imaging performed for another reason. According to Wood, the ideal solution would be a diagnostic biomarker capable of detecting kidney cancer early. Such a marker is not currently available within the scope of the work she described.That places additional importance on prognostic biomarkers. Once a tumor has been detected, clinicians need as much information as possible about how aggressive it may be and how likely it is to progress.Wood’s current work is therefore not attempting to declare directly that a particular patient has metastatic disease. Instead, the goal is to understand what changes biologically as a tumor moves from a less aggressive to a more aggressive state.That means asking which molecular pathways change, which mechanisms become altered, and which analytes may eventually provide useful indicators of tumor behavior.<h4>AIMS and LC-MS answer different questions</h4>A central theme of the interview was the relationship between rapid ambient ionization mass spectrometry and conventional LC-MS.Wood is clear that AIMS is not intended to replace LC-MS. Instead, she sees the two approaches as complementary.AIMS provides a rapid way to obtain a broad molecular overview of a sample with minimal preparation. This makes it especially useful during the discovery phase, when the goal is to gather as much molecular information as possible and identify features that distinguish biological groups.LC-MS then becomes valuable when those features need to be separated, characterized more carefully, and quantified with greater confidence.In Wood’s workflow, rapid MS screening can therefore help identify which analytes deserve closer attention before more targeted LC-MS investigations are performed.<h4>What “minimal sample preparation” actually means</h4>The amount of sample preparation required depends strongly on the type of material being analyzed.Wood currently works mainly with cultured human cell lines, which means much of the preparation begins with growing the cells themselves. Depending on the experiment, the cells may then be chemically lysed or subjected to fixation, paraffin embedding, and sectioning before analysis by LMJ-SSP or DESI.She also notes that the possibilities would be different for freshly excised tumor material. In an appropriate perioperative or biosafety laboratory setting, LMJ-SSP could potentially be used to analyze tumor margins more directly.The practical meaning of “minimal preparation” is therefore highly dependent on the sample and the analytical question being asked.<h4>Why combine LMJ-SSP and DESI?</h4>Rather than choosing between LMJ-SSP and DESI, Wood uses the two approaches because they provide different types of information.LMJ-SSP offers rapid, localized analysis and can accommodate samples with uneven surface topography, which is particularly useful for excised tissue.DESI, by contrast, provides substantially higher spatial resolution. In the workflow described in the interview, DESI can achieve spatial resolution on the order of tens of micrometers, whereas LMJ-SSP operates at a much larger sampling scale depending on probe design.That higher spatial resolution is important when moving from simplified cell-line models toward actual tumor tissue, where the molecular organization of different regions may reveal biologically relevant differences.Combining both techniques therefore enables researchers to balance speed, surface compatibility, and spatial information.<h4>Two mass analyzers for two parts of the same problem</h4>Wood also uses two different mass spectrometers in her LMJ-SSP work.Most of the discovery work is carried out using a triple quadrupole mass spectrometer, particularly because her project focuses strongly on lower-mass analytes and small molecules.Once statistically important analytes have been identified, a Q-TOF instrument can be used for MS/MS experiments and tentative structural identification.The two instruments therefore address different stages of the workflow: one supports broad discovery and comparison, while the other provides additional structural information needed to connect selected features with possible metabolic pathways.<h4>Turning a 3D printer into an automated sampling platform</h4>One of the most unusual elements of the project is the automated sampling system used with LMJ-SSP.Historically, LMJ-SSP measurements could be performed manually or with custom-built XYZ positioning stages. Wood’s laboratory instead adapted a 3D printer into an automated positioning system.Custom software controls the printer and moves the sampling probe with precise control over its X, Y, and Z positions. According to Wood, the system enables movements down to approximately 50 µm and also controls parameters such as the contact time between the probe and sample and the delay between consecutive sampling events.This level of automation improves reproducibility because variables that would otherwise depend on manual operation can be controlled systematically.Even the Z-position can be programmed, allowing the probe to operate at constant or varying heights depending on the sample surface.<h4>Managing high-dimensional MS data</h4>The experimental design creates a large data-analysis challenge.Wood is working with multiple cell lines, both ionization polarities, and more than one mass analyzer. To maintain traceability, she analyzes the data in clearly defined subsets.A typical workflow might begin with one mass analyzer and one polarity. Within that condition, the lower-aggressiveness and higher-aggressiveness cell models can then be compared directly.The data processing pipeline includes steps such as:<ul><li>binning,</li><li>normalization,</li><li>transformation,</li><li>dimensionality reduction,</li><li>identification of discriminating molecular features.</li></ul>Once relevant features are identified, MS/MS analysis can be used to investigate them further. The same process is then repeated across other polarities and instruments.<h4>Unsupervised machine learning reveals distinct molecular profiles</h4>Machine learning is particularly valuable because the AIMS datasets are highly dimensional, containing very large numbers of molecular features across multiple samples.Wood’s initial analysis has included principal component analysis (PCA), an unsupervised dimensionality-reduction technique.The early results are encouraging: the non-metastatic and metastatic cell-line models separate clearly in PCA space.That does not itself identify a definitive biomarker panel, but it indicates that the two biological states have distinguishable molecular profiles even though both belong to the same kidney cancer subtype.This provides an important foundation for identifying which specific metabolites or molecular pathways may be responsible for the separation.<h4>Testing LMJ-SSP for metastatic status</h4>A particularly novel aspect of Wood’s project is the use of LMJ-SSP to investigate differences associated with metastatic status.She had previously worked on distinguishing healthy and cancerous tissues, where the biological differences are relatively large. Comparing two states within the same cancer type is more demanding because the molecular changes may be much subtler.The scientific motivation, however, is strong. Tumors discovered at later stages carry greater concern for metastatic progression, making it important to understand the molecular changes associated with increasingly aggressive behavior.For Wood, this made the methodological risk worthwhile: the analytical challenge directly addresses an area where better prognostic information could ultimately have clinical value.<h4>A long-term goal: rapid MS-based prognostic testing</h4>The long-term vision extends beyond cell-line research.Wood is interested in whether rapid, minimally invasive mass spectrometry could eventually contribute to clinical decision-making.One possibility would be identifying a diagnostic biomarker in a liquid biopsy, potentially using blood or urine. A urine-based marker capable of contributing to earlier detection would be particularly attractive for kidney cancer.For prognostic applications, the goal would be slightly different. Once a tumor is discovered, molecular information could help characterize its likely behavior and provide clinicians with additional evidence when deciding between immediate treatment, surgery, or other management strategies.Wood emphasizes that such a tool would not replace standard clinical workflows. Instead, it would provide additional molecular information to complement existing diagnostic and pathological approaches.<h4>Why interdisciplinary work matters</h4>Throughout the interview, Wood repeatedly returns to the importance of collaboration.Her research sits at the intersection of analytical chemistry, pathology, oncology, computation, and clinical medicine. No single researcher can remain equally current in all of these fields.Working closely with pathologists, computer scientists, surgeons, medical students, and other specialists therefore provides both scientific expertise and a way to stay connected with developments outside one’s immediate discipline.For Wood, the biological context has also changed how she thinks about analytical chemistry. Developing a new instrument or method is important, but understanding who may ultimately benefit from that analytical capability makes the research more meaningful.That patient-centered perspective is now an integral part of how she approaches the project.<h4>An intersection full of opportunities</h4>Wood describes the interface between analytical chemistry and oncology as an especially exciting area for young researchers.The work can range from troubleshooting instrumentation to interpreting pathology, developing statistical methods, and collaborating across disciplines. That diversity creates constant opportunities to learn and to apply analytical chemistry to clinically relevant questions.Her project illustrates that modern mass spectrometry research is increasingly about more than generating spectra. It involves connecting instrumentation, spatial sampling, multivariate statistics, machine learning, biological interpretation, and clinical needs into a single analytical strategy.And in kidney cancer, where reliable prognostic biomarkers remain difficult to establish, that integrated approach may be particularly valuable.<blockquote>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</blockquote><blockquote><h4>Concentrating on Chromatography Podcast</h4>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!You can find Concentrating on Chromatography Podcast in podcast apps:<ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185">Apple podcast</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography">podscan</a></li></ul>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos">YouTube channel</a></blockquote>

AIMS vs. LC-MS for Cancer Diagnostics: ccRCC Metabolomics with Rachel Wood

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Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

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The Thermo Scientific™ FlashSmart™ Elemental Analyzer (EA), based on the modified Dumas Method, is a flexible solution that expands your CHNS/O analysis with over 20 configurations in one system.

<h3>Lead the way in elemental analysis with a single instrument handling all applications.</h3>You and your team can solve more laboratory challenges, improve workflow and minimize downtime. The Thermo Scientific™ FlashSmart™ Elemental Analyzer (EA), based on the modified Dumas Method, is a flexible solution that expands your CHNS/O analysis with over 20 configurations in one system. Powerful software supports automated and precise reports, making everything easier for you and your team.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_2_efeac51a98.jpg" alt="Thermo Scientific™ FlashSmart™ Elemental Analyzer CHNS/O" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_2_efeac51a98.jpg 245w," sizes="100vw" width="1424" height="888"><h3>Why choose the FlashSmart EA?</h3><h4>The confident choice</h4><ul><li>Precise and reliable system that delivers accurate results</li><li>Easy maintenance</li><li>Easy to use for reduced need for staff training</li><li>Modern design combines simple user input with dedicated software features</li><li>Better return on investment as the system is modular and grows with your analytical requirements</li></ul><h4>Simple</h4><ul><li>Gas chromatographic method for real-time view of the analytical process and pathway: anytime, anywhere</li><li>Streamlined sample preparation without the need for dangerous chemicals as Kjeldahl Method</li><li>Complete EA software for effortless operation</li></ul><h4>Modular</h4><ul><li>Over 20 configurations in one instrument: no need for software upgrade</li><li>Up to two autosamplers on the same analyzer</li><li>Higher sample throughput and automation with the Thermo Scientific™ MultiValve Control (MVC) Module, without manual intervention</li><li>Operates with helium and argon as carrier gas</li></ul><h4>Automated</h4><ul><li>Unattended operation of the FlashSmart EA: analyses can run 24/7 for complete results anytime, anywhere</li><li>Dedicated Thermo Scientific™ EagerSmart™ Data</li><li>Handling Software controlling all analytical parameters, Thermo Scientific™ OxyTune™ Function, an autosampler and the MVC Module</li><li>Lower cost per analysis and greater productivity</li></ul><h4>Accurate</h4><ul><li>Certified and uncompromised precision and accuracy for a wide range of applications, from research to routine analysis</li><li>Compliance with most recognized EA Official Methods: AOAC, AOCS, AACC, ASTM, ASBC, ISO, EN, CEN, EPA, IFFO</li><li>OEA CookBook with thousands of determinations and methods for optimal results</li></ul><h4>Robust</h4><ul><li>Robust, specially designed features that you can rely on for decades</li><li>GC separation column operating for years without the need for replacement: it is not a consumable</li><li>Long term investment for your laboratory, which guarantees reliability and accuracy of analysis</li></ul><h3>Access more applications: become the reference laboratory in your field</h3>No matter which direction you take, your lab and equipment will be able to adapt to support any strategy. Flexible systems enable you to react to the new, whilst delivering accurate and reproducible results. With the FlashSmart EA your lab can easily handle varying sample types, obtain from 1 to 5 element determinations and achieve maximum sample throughput.<h4>CHNS/O Analyzer Configuration</h4><ul><li>Perform 5 elements analysis with TCD</li><li>Organic Chemistry: organo-metallic compounds, polymers, plastic, synthetic rubbers, fibers, explosives, catalysts, textiles, pesticides, detergents, and fluorine-compounds.</li><li>Petro-chemistry &amp; Energy: Coals, cokes, crude oils, alternative fuels, petroleum derivates, lubricants, oil additives, and graphite.</li><li>Environmental: Soils, sediments, and rocks, composts, wastes, sewage/sludge, pesticides, water solution, waste water, particulates in air by filters, particulates in water by filters, and woods.</li><li>Material Characterization: Battery, glue/resins, papers, rubbers, cement, ceramics, carbon/glass fibers, tires, pigments and dyes, refractory materials, building materials, inorganic materials, metals, textile fibers, and wood powders.</li></ul><h3>Performance that takes you further</h3>With powerful yet easy operation, your team can process more samples every day. When you need to analyze more elements, you can adapt the FlashSmart EA on-site to your applications or add a second reactor to unlock more capabilities.<h4>Instantly connect</h4><ul><li>Thermal Conductivity Detector (TCD)</li></ul><h4>Sample introduction modularity</h4><ul><li>Up to two Thermo Scientific™ MAS Plus Autosamplers</li><li>One MAS Plus Autosampler and one manual liquid sampler</li></ul><h4>Carrier gas options</h4><ul><li>Helium</li><li>Argon option for lower cost and regular supply</li><li>Switch to nitrogen or argon when in Stand-By Mode</li></ul><h4>Gas chromatographic method: real-time analysis</h4><ul><li>Proper quantification of the five elements</li><li>“Open window” function giving information on what is happening inside the analyzer in real-time</li><li>Straightforward and intuitive workflow without valves</li><li>No absorption or desorption of gases needed</li></ul><figure class="image"><img style="aspect-ratio:1482/903;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_3_ae03e912c7.jpg" alt="Thermo Scientific™ FlashSmart™ Elemental Analyzer CHNS/O" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_3_ae03e912c7.jpg 245w," sizes="100vw" width="1482" height="903"></figure><h3>Software automates consistent sampling and reports</h3><h4>Software</h4>The Thermo Scientific EagerSmart Data Handling Software allows you to leave the FlashSmart EA unattended to get completed analysis, with full, user-friendly reports. The software controls all analytical parameters, flows, autosamplers and detectors, by suggesting the most favourable analytical conditions for your samples.<ul><li>Automated transfer of the sample weight from the balance to the software</li><li>Automated evaluation of Heat Values (Gross and Net Heat Values) for fuels and alternative fuels</li><li>CO2 Emission Trade for environmental control</li><li>Different Protein Factors for food and animal feed</li><li>Inserting of the Humidity value for solid samples and of the Density for liquid samples</li><li>Automated Minimal Formula determination for pharmaceutical or fine chemicals applications</li><li>Automated evaluation of C/N, C/H and C/S ratio</li><li>Automated data transfer to Microsoft Excel, LIMS and others</li></ul><h4>Automated functions</h4><ul><li>Auto-Start</li><li>Auto-Ready</li><li>Auto-Stand-By</li><li>Auto-Off</li><li>Auto Leak Test</li></ul><h4>Unique and dedicated OxyTune function</h4>The Thermo Scientific OxyTune Function automatically evaluates the oxygen needed for combustion, according to the weight and nature of your sample.<h4>MultiValve Control Module: future-proof lab with more throughput and less costs</h4>By switching the analysis from the left channel to the right one (or viceversa), the MVC Module increases your analysis throughput. When the system is not in use overnight, on weekends, or for a prolonged period of time you can also reduce helium consumption and overall cost of analysis by switching from helium to nitrogen or argon.<ul><li>Fully automated and software controlled</li><li>No need to change hardware or software configuration</li><li>Optional feature for extended lab throughput</li><li>Easy to add</li></ul>

Thermo Scientific™ FlashSmart™ Elemental Analyzer NC/Soil

<h3>Lead the way in elemental analysis with a single instrument handling all applications.</h3>You and your team can solve more laboratory challenges, improve workflow and minimize downtime. The Thermo Scientific™ FlashSmart™ Elemental Analyzer (EA), based on the modified Dumas Method, is a flexible solution that expands your CHNS/O analysis with over 20 configurations in one system. Powerful software supports automated and precise reports, making everything easier for you and your team.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_2_efeac51a98.jpg" alt="Thermo Scientific™ FlashSmart™ Elemental Analyzer NC/Soil" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_2_efeac51a98.jpg 245w," sizes="100vw" width="1424" height="888"><h3>Why choose the FlashSmart EA?</h3><h4>The confident choice</h4><ul><li>Precise and reliable system that delivers accurate results</li><li>Easy maintenance</li><li>Easy to use for reduced need for staff training</li><li>Modern design combines simple user input with dedicated software features</li><li>Better return on investment as the system is modular and grows with your analytical requirements</li></ul><h4>Simple</h4><ul><li>Gas chromatographic method for real-time view of the analytical process and pathway: anytime, anywhere</li><li>Streamlined sample preparation without the need for dangerous chemicals as Kjeldahl Method</li><li>Complete EA software for effortless operation</li></ul><h4>Modular</h4><ul><li>Over 20 configurations in one instrument: no need for software upgrade</li><li>Up to two autosamplers on the same analyzer</li><li>Higher sample throughput and automation with the Thermo Scientific™ MultiValve Control (MVC) Module, without manual intervention</li><li>Operates with helium and argon as carrier gas</li></ul><h4>Automated</h4><ul><li>Unattended operation of the FlashSmart EA: analyses can run 24/7 for complete results anytime, anywhere</li><li>Dedicated Thermo Scientific™ EagerSmart™ Data</li><li>Handling Software controlling all analytical parameters, Thermo Scientific™ OxyTune™ Function, an autosampler and the MVC Module</li><li>Lower cost per analysis and greater productivity</li></ul><h4>Accurate</h4><ul><li>Certified and uncompromised precision and accuracy for a wide range of applications, from research to routine analysis</li><li>Compliance with most recognized EA Official Methods: AOAC, AOCS, AACC, ASTM, ASBC, ISO, EN, CEN, EPA, IFFO</li><li>OEA CookBook with thousands of determinations and methods for optimal results</li></ul><h4>Robust</h4><ul><li>Robust, specially designed features that you can rely on for decades</li><li>GC separation column operating for years without the need for replacement: it is not a consumable</li><li>Long term investment for your laboratory, which guarantees reliability and accuracy of analysis</li></ul><h3>Access more applications: become the reference laboratory in your field</h3>No matter which direction you take, your lab and equipment will be able to adapt to support any strategy. Flexible systems enable you to react to the new, whilst delivering accurate and reproducible results. With the FlashSmart EA your lab can easily handle varying sample types, obtain from 1 to 5 element determinations and achieve maximum sample throughput.<h4>NC Soil Configuration</h4><ul><li>Determination of Total Nitrogen, Total Carbon, and Total Organic Carbon.</li><li>Environmental: Soils, sediments, and rocks, composts, wastes, sewage/sludge, pesticides, water solution, waste water, particulates in air by filters, particulates in water by filters, and woods.</li><li>Material Characterization: Battery, glue/resins, papers, rubbers, cement, ceramics, carbon/glass fibers, tires, pigments and dyes, refractory materials, building materials, inorganic materials, metals, textile fibers, and wood powders.</li><li>Agronomy &amp; Marine Science: Soil, plants (leaves, roots, fruit), sediments, humus, algae, plankton, particulate matter in water by filters, water, and fertilizer.</li></ul><h3>Performance that takes you further</h3>With powerful yet easy operation, your team can process more samples every day. When you need to analyze more elements, you can adapt the FlashSmart EA on-site to your applications or add a second reactor to unlock more capabilities.<h4>Instantly connect</h4><ul><li>Thermal Conductivity Detector (TCD)</li></ul><h4>Sample introduction modularity</h4><ul><li>Up to two Thermo Scientific™ MAS Plus Autosamplers</li><li>One MAS Plus Autosampler and one manual liquid sampler</li></ul><h4>Carrier gas options</h4><ul><li>Helium</li><li>Argon option for lower cost and regular supply</li><li>Switch to nitrogen or argon when in Stand-By Mode</li></ul><h4>Gas chromatographic method: real-time analysis</h4><ul><li>Proper quantification of the five elements</li><li>“Open window” function giving information on what is happening inside the analyzer in real-time</li><li>Straightforward and intuitive workflow without valves</li><li>No absorption or desorption of gases needed</li></ul><figure class="image"><img style="aspect-ratio:1482/903;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_3_ae03e912c7.jpg" alt="Thermo Scientific™ FlashSmart™ Elemental Analyzer NC/Soil" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Flash_Smart_Elemental_Analyzer_CHNS_O_3_ae03e912c7.jpg 245w," sizes="100vw" width="1482" height="903"></figure><h3>Software automates consistent sampling and reports</h3><h4>Software</h4>The Thermo Scientific EagerSmart Data Handling Software allows you to leave the FlashSmart EA unattended to get completed analysis, with full, user-friendly reports. The software controls all analytical parameters, flows, autosamplers and detectors, by suggesting the most favourable analytical conditions for your samples.<ul><li>Automated transfer of the sample weight from the balance to the software</li><li>Automated evaluation of Heat Values (Gross and Net Heat Values) for fuels and alternative fuels</li><li>CO2 Emission Trade for environmental control</li><li>Different Protein Factors for food and animal feed</li><li>Inserting of the Humidity value for solid samples and of the Density for liquid samples</li><li>Automated Minimal Formula determination for pharmaceutical or fine chemicals applications</li><li>Automated evaluation of C/N, C/H and C/S ratio</li><li>Automated data transfer to Microsoft Excel, LIMS and others</li></ul><h4>Automated functions</h4><ul><li>Auto-Start</li><li>Auto-Ready</li><li>Auto-Stand-By</li><li>Auto-Off</li><li>Auto Leak Test</li></ul><h4>Unique and dedicated OxyTune function</h4>The Thermo Scientific OxyTune Function automatically evaluates the oxygen needed for combustion, according to the weight and nature of your sample.<h4>MultiValve Control Module: future-proof lab with more throughput and less costs</h4>By switching the analysis from the left channel to the right one (or viceversa), the MVC Module increases your analysis throughput. When the system is not in use overnight, on weekends, or for a prolonged period of time you can also reduce helium consumption and overall cost of analysis by switching from helium to nitrogen or argon.<ul><li>Fully automated and software controlled</li><li>No need to change hardware or software configuration</li><li>Optional feature for extended lab throughput</li><li>Easy to add</li></ul>

Thermo Scientific ARL X900 XRF Spectrometer

Powerful WDXRF spectrometer with optional XRD, dual-loading, and combined sequential/simultaneous analysis for fast, precise results in metals, cement, and mining industries.

The Thermo Scientific™ ARL™ X900 XRF Spectrometer is a robust, next-generation wavelength-dispersive X-ray fluorescence (WDXRF) analyzer with optional integrated XRD capability, tailored for the most demanding industrial environments in metals, cement, and mining industries. It delivers fast, precise elemental and phase composition results with exceptional reliability and uptime.Thanks to its inherently safe "tube above sample" geometry, a large single vacuum chamber, and dual-sample loader, the ARL X900 ensures high throughput and stable long-term operation—even under harsh conditions. It combines simultaneous and sequential WDXRF capabilities with flexible configurations that include up to 32 fixed monochromators and up to two gearless goniometers.<h3>Application Domains</h3><ul><li>Metals: Iron, steel, pig iron, DRI, slags, ferro-alloys, copper/brass/bronze, aluminum alloys (including bath ratio), zinc, tin, nickel, cobalt, titanium, magnesium, super-alloys.</li><li>Cement: Raw meal, clinker, free lime, clinker phases, limestone, slags, refractories, ceramics.</li><li>Mining &amp; Minerals: Rocks, ores, concentrators, general oxides, soils and sediments, fluorspar.</li><li>Other Industries: Glass, ceramics, polymers, contract laboratories.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_X900_XRF_Spectrometer_3_6602834bbd.jpg" alt="Thermo Scientific™ ARL™ X900 XRF Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_X900_XRF_Spectrometer_3_6602834bbd.jpg 158w," sizes="100vw" width="1023" height="1009"><h3>Key Features</h3><ul><li>Combined simultaneous and sequential WDXRF for ultimate speed and analytical flexibility.</li><li>Tube-above-sample geometry protects the X-ray tube from contamination or breakage.</li><li>Single large vacuum chamber provides stable analytical conditions and protects sensitive components.</li><li>5GN+ X-ray tube and high-power generator deliver higher X-ray intensity and lower detection limits.</li><li>Fixed channel monochromators for ultra-fast simultaneous analysis with no moving parts.</li><li>Gearless goniometers enable precise sequential scanning with high durability and no mechanical wear.</li><li>Compact XRD system for phase identification and quantification in a single instrument.</li><li>SCX detectors provide enhanced precision for matrix elements.</li><li>Dual-sample loader allows pre-loading of the next sample, significantly reducing dead time.</li><li>20-position rotary or large XY magazines support unattended operation.</li><li>Automation-ready with integration options for SMS robotic systems.</li><li>Turnkey calibrations with certified reference materials ensure immediate use and reliable results.</li><li>UniQuant™ standardless analysis delivers results of unknown samples within minutes.</li><li>OXSAS™ analytical software offers intuitive operation, process control, batch analysis, and powerful calibration tools.</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_X900_XRF_Spectrometer_4_2eae64f7ba.jpg" alt="Thermo Scientific™ ARL™ X900 XRF Spectrometer: Cross-section of the ARL X900 Spectrometer, showing the instrument components that ensure high uptime and stable analytical results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_X900_XRF_Spectrometer_4_2eae64f7ba.jpg 206w," sizes="100vw" width="1373" height="1042"><h3>Efficiency and Flexibility</h3>By combining fast sequential analysis, high-speed fixed-channel detection, and concurrent sample handling, the ARL X900 optimizes throughput. It minimizes measurement cycle times, making it ideal for high-volume production control, failure analysis, and R&amp;D applications.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_X900_XRF_Spectrometer_5_234ac79d92.jpg" alt="Thermo Scientific™ ARL™ X900 XRF Spectrometer: ARL X900 Spectrometer integrates fixed channels for simultaneous analysis and a goniometer for sequential WDXRF analysis, combining two essential techniques within a single instrument." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_X900_XRF_Spectrometer_5_234ac79d92.jpg 221w," sizes="100vw" width="1474" height="1042"><h3>Automation and Software</h3>With Thermo Scientific™ OXSAS™ software, the ARL X900 supports fully automated, unattended 24/7 operation. Features include:<ul><li>EasyOXSAS interface for streamlined routine workflows.</li><li>Real-time SPC (Statistical Process Control).</li><li>Analytical Assistant and multivariable regression for optimized calibration.</li><li>SCT Manager for tracking control, set-up, and standard samples.</li></ul><h3>Service and Support</h3>Thermo Fisher Scientific provides global service logistics, expert field engineers, and flexible service agreements. Whether it’s during installation, warranty, or post-warranty periods, you benefit from:<ul><li>Increased productivity and uptime.</li><li>Access to expert advice and application support.</li><li>Custom training to fully leverage your instrument’s capabilities.</li></ul>Unlock the power of the ARL X900 Spectrometer and ensure your elemental analysis meets the highest standards of speed, precision, and reliability.

Thermo Scientific ARL 9900 IntelliPower Series

Powerful WDXRF analyzer with optional XRD for real-time elemental and phase analysis of solids. Configurable with up to 32 channels and 3 goniometers for fast, precise process control.

The Thermo Scientific™ ARL™ 9900 IntelliPower Series spectrometer is a powerful and versatile WDXRF analyzer with optional integrated XRD, designed for high-performance, real-time process control in demanding industrial environments. It enables rapid, precise, and fully automated elemental and phase analysis of solid samples such as metals, cement, and minerals.With up to 32 fixed monochromators and one to three gearless goniometers, the ARL 9900 performs both simultaneous and sequential elemental analysis across a wide range—from boron to americium (Z=5–95). It can be enhanced with a compact X-ray diffraction (XRD) module to deliver phase-specific data, such as free lime content, clinker phases, and iron compounds in DRI processes.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_9900_Intelli_Power_Series_3_75f234904f.jpg" alt="Thermo Scientific™ ARL™ 9900 IntelliPower Series: Integration of XRF and XRD in the same instrument: one sample, one instrument, one analysis for two techniques." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_9900_Intelli_Power_Series_3_75f234904f.jpg 237w," sizes="100vw" width="1143" height="753"><h3>Applications</h3><ul><li>Metals: iron, steel, aluminum, copper, zinc, nickel, titanium, magnesium alloys, slags, and sinters</li><li>Cement: raw meal, clinker, free lime, clinker phases, limestone, additives</li><li>Mining &amp; Minerals: ores, rocks, beach sands, sediments, industrial minerals</li><li>Other Materials: ceramics, glass, polymers, soils</li><li>By-products: process residues and waste materials</li></ul><h3>Key Features</h3><ul><li>Fully integrated simultaneous and sequential WDXRF analysis in one instrument</li><li>Configurable with up to 24 fixed channels and one or more goniometers for ultra-fast, high-precision analysis</li><li>Rapid and reliable sample introduction system with multiple automation levels</li><li>Wide detection range: from parts per million (ppm) to 100% concentration</li><li>LoVap™ X-ray tube with 50 μm Be window for long-term stability and enhanced performance</li><li>Modular IntelliPower platform available in 1500 W, 2500 W, and 4200 W configurations</li><li>Ultra-low detector gas consumption</li><li>Optional integrated XRD module for qualitative and quantitative phase analysis</li><li>Scalable design to meet evolving analytical requirements</li><li>Factory calibration ensures fast commissioning and immediate operational readiness</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_ARL_9900_Intelli_Power_Series_e194c316bb.jpg" alt="Thermo Scientific™ ARL™ 9900 IntelliPower Series" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_ARL_9900_Intelli_Power_Series_e194c316bb.jpg 128w," sizes="100vw" width="650" height="795"><h3>X-ray System</h3><ul><li>X-ray tube mounted above the sample: protects the system from fragile or damaged samples</li><li>Thermostatically regulated spectrometer: ensures consistent analytical conditions and excellent measurement stability</li></ul><h3>Fixed Monochromators</h3><ul><li>Up to 32 fixed channel monochromators for full simultaneous operation</li><li>Compact slit-crystal geometry: optimized for low detection limits and rapid analysis of dedicated elements</li></ul><h3>XRF Goniometers</h3><ul><li>Programmable for both quantitative and qualitative analysis</li><li>Moiré fringe technology ensures fast, gearless sequential X-ray spectrometry with excellent angular precision</li><li>SmartGonio: compact system covering F to Am with up to 3 crystals</li><li>Universal goniometer: extended coverage from B to Am with up to 9 crystals and 4 collimators</li></ul><h3>Calibration Options</h3><ul><li>Fully factory-calibrated for a broad range of sample types including: cast irons, steels, brasses, bronzes, copper, aluminum, zinc, tin, magnesium, nickel, titanium, cobalt, ferro-alloys, cement, minerals, slags, limestone, ceramics, glass, soils, sediments, rocks, and polymers</li><li>XRD calibrations available for: free lime, clinker phases (C3S, C2S, C3A, C4AF), amorphous content in clinker, DRI phases, and more</li></ul><h3>Automation</h3><ul><li>Fast and dependable sample introduction with scalable automation</li><li>Compatible with ARL SMS systems for fully automated online process control, including integrated sample preparation</li></ul>

Thermo Scientific Niton XL5 Plus Handheld XRF Analyzer

Confidently perform elemental analysis with the Thermo Scientific™ Niton™ XL5 Plus handheld XRF analyzer; it delivers unprecedented performance even for lightweight elements.

Confidently perform elemental analysis with the Thermo Scientific™ Niton™ XL5 Plus handheld XRF analyzer; it delivers unprecedented performance even for lightweight elements. Identify pure metals and alloys, detect tramp elements, or obtain geochemical data.&nbsp;Industrial businesses rely on the Niton XL5 Plus analyzer for more than just low detection limits. It generates fast results and offers great versatility such as the ability to scan a broad range of materials with a single analyzer.More than 75,000 Niton handheld XRF analyzers have been deployed worldwide since 1994, making them the trusted standard for in-field elemental analysis.<div><h3>⚙️ Features</h3><ul><li>5W X-ray tube</li><li>Proprietary large area drift detector for light element detection (Mg, Al, Si, P, S)</li><li>Lightweight design (2.8 lbs/ 1.3 kg)</li><li>Miniaturized nose</li><li>WiFi enabled</li><li>Macro and micro cameras</li><li>Hot swap battery</li><li>Tilting, color touchscreen</li><li>Directional keys</li><li>Password protected security</li><li>IP54 certified (splash/dust proof)</li></ul><h3>🧪 Applications</h3><ul><li>Verification of metals and alloys in manufacturing operations</li><li>Non-destructive field inspections for positive material identification</li><li>Point-and-shoot sorting at scrap recycling operations</li><li>Coating thickness measurements for single or binary metal layers</li><li>Precious metal assay of bullion and jewelry</li><li>Real-time geochemical analysis for mining exploration</li><li>On-site heavy metal screening of polluted soils</li><li>Screening of hazardous substances in consumer goods</li><li>Custom applications on demand</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_5_Plus_Handheld_XRF_Analyzer_2_2967c6cd9a.jpg" alt="Thermo Scientific™ Niton™ XL5 Plus Handheld XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_5_Plus_Handheld_XRF_Analyzer_2_2967c6cd9a.jpg 156w," sizes="100vw" width="650" height="650"><h3>📏 Specifications</h3><ul><li>Certifications/Compliance: CE, RoHS, FCC, Industry Canada, Safety to IEC 61010-1:2010</li><li>Data Entry:<ul><li>Touchscreen keyboard</li><li>User customizable data entry</li><li>Optional wireless remote barcode reader</li></ul></li><li>Data Storage: 512 MB internal system memory / 16 GB industrial grade storage; Stores approximately 130,000 readings with spectra (fewer if macro and micro images are saved)</li><li>Data Transfer: WiFi, USB-c</li><li>Dimensions (L × W × H): 9.54 × 8.19 × 2.67 in. (24.23 × 20.8 × 6.78 cm)</li><li>Display Type: Tilting, color, resistive touchscreen display</li><li>Global Positioning System: Internal GPS and optional external GPS (via Bluetooth); GPS data are included with the sample information. NOTE: The GPS function is an optional feature.</li><li>Languages: English, Chinese, Spanish, Portuguese, Russian, Japanese, German, Korean, French, Turkish, Italian</li><li>Libraries: Default alloy libraries based on SAE, AISI, ASTM, AA, DIN, GB standards. Users may create, clone and edit libraries.</li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Operating Environment:<ul><li>Temperature: 0°C to 50°C (external fan recommended when ambient temperature is greater than 33°C)</li><li>Humidity: 10% to 90% relative humidity non-condensing</li></ul></li><li>Operating System: Linux</li><li>Optional Accessories:<ul><li>Portable test stand</li><li>Mini test stand</li><li>Desk/wall holder</li><li>Hotwork stand off</li><li>Soil guard</li><li>Belt holster</li><li>Bluetooth printer</li></ul></li><li>Power Consumption: 12V lithium-ion battery, or 12V DC, 3A, 3.6W power supply. Hot swap functionality keeps analyzer powered during battery replacements.</li><li>Security Features: Password-protected user security</li><li>Software: Support software: NitonConnect PC software</li><li>Spot Size:<ul><li>Standard: 8mm collimation</li><li>Optional: 3mm small-spot collimation</li></ul></li><li>Standard Accessories:<ul><li>Locking shielded carrying case</li><li>Two (2) lithium-ion battery packs</li><li>One (1) 110/220 VAC battery charger/AC adapter</li><li>Check samples</li><li>Safety lanyard</li><li>PC connection cable (USB)</li></ul></li><li>System Details: Built-in standardization and health check verify system integrity and operating conditions</li><li>Type: XL5 Plus Handheld XRF Analyzer</li><li>Weight (English): 2.8 lb. with battery</li><li>Weight (Metric): 1.3 kg with battery</li><li>X-Ray Source Type:<ul><li>X-ray tube: Ag anode (6–50kV, 0–500µA, 5W max)</li><li>Filter: Six (6) position filter wheel for enhanced spectral range coverage</li><li>Current: Dynamically adjustable current for optimal sensitivity on every analysis</li></ul></li><li>Detector Type: High count rate, high resolution, extra large area silicon drift detector (11µm graphene window). Detector ProGuard protection included.</li><li>Unit Size: Each</li></ul><h3>Which analyzer for your application?</h3><figure class="image"><img style="aspect-ratio:1024/1102;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></figure><blockquote><h3>Helpful links</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-selection-guide.html">Which XRF analyzer is right for me?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-rental-leasing.html">Should I rent or lease this product?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/xrf-radiation-safety-training.html">Where can I get radiation safety training?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/spectroscopy-elemental-isotope-analysis-learning-center/elemental-analysis-information/xrf-technology.html">What is XRF Technology?</a></li><li>What are the applications for this handheld XRF analyzer?<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-scrap-metal-recycling-analysis.html">Scrap Metal Recycling</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-manufacturing-metal-fabrication-analysis.html">Manufacturing and Metal Fabrication</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/positive-material-identification-oil-gas.html">Positive Material Identification</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-mining-exploration-solutions.html">Mining and Exploration</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-precious-metals-jewelry-analysis.html">Precious Metals</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-consumer-safety-regulatory-solutions.html">Consumer Safety &amp; Regulatory</a></li></ul></li></ul></blockquote></div>

Thermo Scientific Niton XL3t XRF Analyzer

Perform nondestructive testing and get results in seconds for metal analysis, mining and exploration and lead paint testing for toys and consumer goods using handheld analyzers.

<div><div>When you need nondestructive testing with results in seconds for metal analysis, mining and exploration, and lead paint testing for toys and consumer goods, the Thermo Scientific™ Niton™ XL3t XRF Analyzer is the definitive tool for scrap metal recycling, casting and fabrication, manufacturing QA/QC and positive material identification.&nbsp;Get real-time compliance testing, including screening of incoming materials and outgoing finished goods, for the Consumer Product Safety Improvement Act (CPSIA), Proposition 65, Restriction of Hazardous Substances (RoHS) and other regulations.</div><div>The feature-leading, handheld Niton XL3t XRF Analyzer offers features engineered to improve your productivity and profitability.</div><h3>⚙️ Features</h3><ul><li>High sensitivity and measurement accuracy.</li><li>Lower detection limits for higher-Z elements, with additional elements Mg, Al, Si and P via helium purge.</li><li>Standard analytical range: 25 elements from S to U.</li><li>Optional CCD camera for visually identifying and recording images of samples.</li><li>A user-selectable 3mm small spot to locate areas of interest on a sample.</li><li>Flip-up, color, touch-screen display.</li><li>Ergonomic design.</li><li>Easy-to-use software.</li><li>50 kV x-ray tube provides approximately twice the x-ray flux of a 40 kV x-ray tube.</li><li>Hotfoot hot surface adaptor allows testing in petrochemical refineries up to 842°F (450°C).</li></ul></div><div><h3>🔗 Connectivity</h3><ul><li>Integrated USB and Bluetooth™ communications provide direct data transfer to your PC or networked storage device. &nbsp;</li><li>Standard Thermo Scientific™ Niton Data Transfer (NDT™) PC software allows you to: &nbsp;<ul><li>Set operator permissions &nbsp;</li><li>Generate custom reports &nbsp;</li><li>Print certificates of analysis &nbsp;</li><li>Remotely monitor and control the instrument from your PC &nbsp;</li></ul></li><li>Optional accessories: Bluetooth barcode reader, Bluetooth printer, Bluetooth GPS</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_3t_XRF_Analyzer_b0796bdd58.jpg" alt="Thermo Scientific™ Niton™ XL3t XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_3t_XRF_Analyzer_b0796bdd58.jpg 94w," sizes="100vw" width="650" height="1083"><h3>📏 Specifications</h3><ul><li>Applications: Elemental Analysis</li><li>Available Analytical Modes: Varies by Application<ul><li>Alloy Modes: Metal Alloy, Electronics Alloy, Precious Metals</li><li>Bulk Modes: Mining, Soil</li><li>Plastic Modes: RoHS Plastics, Toy and Consumer Goods Plastics, TestAll Painted Products</li><li>Other Modes: Lead Paint, Thin Sample</li></ul></li><li>Data Memory: 32Mb internal system memory / 128Mb internal user storage</li><li>Description: Niton XL3t XRF Analyzer</li><li>Detector Type: High-performance Semiconductor</li><li>Display Type: Adjustable angle, color, touch-screen display</li><li>Item Description: XL3t Analyzer; Portable</li><li>Height (English): 3.75 in.</li><li>Height (Metric): 95.5 mm</li><li>Length (English): 9.6 in.</li><li>Length (Metric): 244 mm</li><li>Width (English): 9.05 in.</li><li>Width (Metric): 230 mm</li><li>Optional Accessories:<ul><li>Portable test stand, stationary test stand, tripod stand;</li><li>Extenda-Pole™ extension pole;</li><li>Welding Mask;</li><li>HotFoot™ hot surface adapter;</li><li>Soil testing guard;</li><li>Internal CCD sample imaging system;</li><li>Variable spot size aperture</li></ul></li><li>Power Consumption: 100 µA</li><li>Security Features: Password-protected user security</li><li>Standard Accessories:<ul><li>Locking shielded carrying case, RFID reader, Shielded belt holster,</li><li>Two 4 (or optional 6) -cell lithium-ion battery packs,</li><li>Spare battery pack, 110/220 VAC battery charger/AC adaptor,</li><li>PC connection cables (USB and RS-232),</li><li>Niton Data Transfer (NDT™) PC software,</li><li>Safety lanyard, Check samples/standards</li></ul></li><li>Tube Type: Au anode 50kV maximum, 200µA maximum</li><li>Tube Voltage: 50 kV</li><li>Weight (English): 3 lb.</li><li>Weight (Metric): 1.3 kg</li><li>Voltage: 50 kV</li><li>Dimensions (L × W × H): 9.6 × 9.05 × 3.75 in. (244 × 230 × 95.5 mm)</li><li>Operating System: Ownership</li><li>Certifications/Compliance: CE, RoHS</li><li>Max. Power: 2W</li><li>Unit Size: Each</li></ul></div>

Thermo Scientific Niton XL2 Plus Handheld XRF Analyzer

Obtain fast, accurate elemental analysis for metal and alloy identification, PMI testing and more with the Niton™ XL2 Plus Handheld XRF Analyzer.

<div>Confidently perform elemental analysis with the Thermo Scientific™ Niton™ XL2 Plus handheld XRF analyzer. When durability, performance and productivity are top of mind, industrial businesses rely on the Niton XL2 Plus handheld XRF analyzer for fast results and low detection limits.&nbsp;Identify pure metals and alloys, or obtain geochemical data, the Niton XL2 Plus provides operators the ability to scan a broad range of materials in one versatile analyzer.</div>More than 75,000 Niton handheld XRF analyzers have been deployed worldwide since 1994, making them the trusted standard for in-field elemental analysis.<div><h3>⚙️ Features &amp; Benefits</h3><ul><li>2W X-Ray Tube</li><li>Silicon Drift Detector (SDD) for light element detection (Mg, Al, Si, P, S)</li><li>Detector ProGuard Protection</li><li>Micro Camera</li><li>Hot Swap Battery</li><li>Touch Screen and Directional Keys</li><li>Password Protected Security</li><li>IP54 Certified (Splash/ Dust Proof)</li><li>Nose Cone Alignment Guides</li></ul><h3>🧪 Applications</h3><ul><li>Verification of metals and alloys in manufacturing</li><li>Quality Assurance testing for positive material identification</li><li>Point-and-shoot sorting at scrap recycling operations</li><li>Coating thickness measurements from single element layers</li><li>Precious metal assay of bullion and jewelry</li><li>Geochemical analysis for ore trading and grade control</li><li>On-site heavy metal screening of polluted soils</li><li>Lead in paint inspection of industrial facilities</li><li>Screening of hazardous substances in consumer goods</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_2_Plus_Handheld_XRF_Analyzer_3_cb63ae77a5.jpg" alt="Thermo Scientific™ Niton™ XL2 Plus Handheld XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_2_Plus_Handheld_XRF_Analyzer_3_cb63ae77a5.jpg 156w," sizes="100vw" width="650" height="650"><h3>📏 Specifications</h3><ul><li>Analytical Range: Mg–U</li><li>Available Analytical Modes: General Metals, Precious Metals, Coatings, Mining, Soils, Electronic Alloys, Plastics, Industrial Lead in Paint, Lead in Paint Products</li><li>Bluetooth: Supports print functionality, external GPS connectivity and barcode reader</li><li>Camera: Integrated CCD micro camera for locating and recording measurement positions</li><li>Certifications/Compliance: CE, RoHS, FCC, Industry Canada, Safety to IEC 61010-1, UL 61010-1, IP54 (splash and dust proof)</li><li>Data Entry:&nbsp;<ul><li>Touchscreen keyboard</li><li>User customizable data entry</li><li>Optional wireless remote barcode reader</li></ul></li><li>Data Storage:<ul><li>64 MB internal system memory / 128 MB internal user storage</li><li>Stores approximately 10,000 readings with spectra (fewer if images are saved)</li></ul></li><li>Data Transfer: USB, Bluetooth, RS-232 serial communication</li><li>Description: Niton XL2 Plus Handheld XRF Analyzer</li><li>Dimensions (L × W × H): 10 × 10.8 × 3.9 in (25.6 × 27.5 × 10 cm)</li><li>Display Type: Fixed angle, color, resistive touchscreen display</li><li>Global Positioning System: Optional external GPS (via Bluetooth)</li><li>Languages: English, Chinese, Spanish, Portuguese, Russian, Japanese, German, Korean, French, Italian, Czech</li><li>Libraries:&nbsp;<ul><li>Default alloy libraries based on SAE, AISI, ASTM, AA standards</li><li>Users may create and edit libraries</li></ul></li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Operating Environment:<ul><li>Temperature: -10 °C to 50 °C</li><li>Humidity: 0% to 80% relative humidity non-condensing</li></ul></li><li>Operating System: Proprietary</li><li>Optional Accessories:<ul><li>Thermo Scientific™ portable test stand</li><li>Thermo Scientific™ mobile test stand</li><li>Thermo Scientific™ field mate test stand</li><li>Thermo Scientific™ soil guard</li></ul></li><li>Power Consumption:<ul><li>7.4V lithium-ion battery, or 12V DC, 3A, 36W power supply</li><li>Hot swap functionality keeps analyzer powered during battery replacements</li></ul></li><li>Security Features: Password-protected user security</li><li>Software: Support Software: Niton Data Transfer (NDT) PC software</li><li>Spot Size: 8 mm collimation</li><li>Standard Accessories:<ul><li>Locking shielded carrying case</li><li>Two (2) lithium-ion battery packs</li><li>One (1) 110/220 VAC battery charger/ AC adaptor</li><li>Check samples</li><li>Belt holster</li><li>Safety lanyard</li><li>PC connection cables (USB and RS-232)</li></ul></li><li>System Details: Built-in standardization via automatic system check</li><li>Weight (English): 3.4 lbs with battery</li><li>Weight (Metric): 1.53 kg with battery</li><li>X-Ray Source Type:<ul><li>X-Ray Tube: Ag anode (6–45 kV, 1–200 µA, 2W max)</li><li>Dynamically adjustable current for optimal sensitivity on every analysis</li></ul></li><li>Applications: Identify pure metals and alloys, detect tramp elements, or obtain geochemical data</li><li>Detector Type:&nbsp;<ul><li>Silicon Drift Detector (SDD)</li><li>Detector ProGuard protection included</li></ul></li><li>Tube Voltage: 6 to 45 kV</li><li>Unit Size: Each</li></ul><h3>Which analyzer for your application?</h3><figure class="image"><img style="aspect-ratio:1024/1102;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></figure><blockquote><h3>Helpful links</h3><ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-selection-guide.html">Which XRF analyzer is right for me?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-xrf-analyzer-rental-leasing.html">Should I rent or lease this product?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/xrf-radiation-safety-training.html">Where can I get radiation safety training?</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/spectroscopy-elemental-isotope-analysis-learning-center/elemental-analysis-information/xrf-technology.html">What is XRF Technology?</a></li><li>What are the applications for this handheld XRF analyzer?<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-scrap-metal-recycling-analysis.html">Scrap Metal Recycling</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-manufacturing-metal-fabrication-analysis.html">Manufacturing and Metal Fabrication</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/positive-material-identification-oil-gas.html">Positive Material Identification</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-mining-exploration-solutions.html">Mining and Exploration</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-metal-manufacturing-inspection-recycling-solutions/portable-precious-metals-jewelry-analysis.html">Precious Metals</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/portable-analysis-material-id/portable-consumer-safety-regulatory-solutions.html">Consumer Safety &amp; Regulatory</a></li></ul></li></ul></blockquote></div>

Thermo Scientific Niton XL3t GOLDD+ XRF Analyzer

High-performance handheld XRF analyzer with GOLDD™ technology for fast, accurate analysis of metals, light elements, ores, soils and contaminants – no helium or vacuum needed.

<div><div><div>Industries from mining and exploration to scrap metal recycling depend on fast, accurate elemental analysis. The Thermo Scientific™ Niton™ XL3t GOLDD+ XRF Analyzer provides reliable, real-time data for sample identification and positive material identification for even difficult-to-analyze light elements, without helium purging or vacuum pumps.&nbsp;The Niton XL3t GOLDD+ Analyzer delivers a feature-rich package enhanced with Geometrically Optimized Large Area Drift Detector (GOLDD™) technology for improved light element (Mg-S) analysis, the lowest limits of detection and fastest measurement times.</div><div><h3>⚡ Performance:</h3>GOLDD Technology:&nbsp;When low detection limits and high sample throughput are critical, the Niton XL3t GOLDD+ XRF analyzer delivers measurement times up to 10-times faster than conventional Si-PIN detectors and up to 3-times more precise than conventional smaller silicon drift detectors (SDD) - without helium purge or vacuum. For further enhancing light element analysis, a helium purge option is available. Niton analyzers also feature the highest performance X-ray tube and speed detector available on the market.<h3>🧪 Wide Range of Applications:</h3><ul><li>Scrap Metal Recycling:&nbsp;<ul><li>Sorts aluminum, titanium and bronze alloys, and achieves superior performance for tramp and trace element analysis.</li></ul></li><li>Mining Exploration:&nbsp;<ul><li>Fast, accurate analysis of light elements.&nbsp;</li><li>Identifies anomalies near the averages naturally found in the earth's crust.&nbsp;</li><li>Facilitates advanced exploration and soil analysis, concentrate measurement, ore blending, precious metal identification and lab analysis prequalification.</li></ul></li><li>Environmental:&nbsp;<ul><li>Detects contaminants such as chlorine and sulfur in sediment and arsenic in soil.&nbsp;</li><li>Identifies environmental hazards in residential, commercial and industrial settings, such as toxic drywall.</li></ul></li></ul></div></div><h3>⚙️ Features</h3><ul><li>Standard analytical range: Up to 30 elements from Mg to U (varies by application).</li><li>Most powerful x-ray tube on the market for handheld XRF analysis.</li><li>Point and shoot simplicity- very easy to use even by nontechnical personnel.</li><li>Rugged design for real-world industrial environments.</li><li>Nondestructive analysis with near instantaneous results.</li><li>Sealed against moisture and dust.</li><li>Ergonomically designed.</li><li>Daylight-readable icons.</li><li>Incorporates multi-language options.</li><li>Color, touch-screen display.</li></ul></div><div><h3>🔗 Connectivity</h3><ul><li>Integrated USB and Bluetooth™ communications provide direct data transfer to your PC or networked storage device. &nbsp;</li><li>Standard Thermo Scientific™ Niton Data Transfer (NDT™) PC software allows you to: &nbsp;<ul><li>Set operator permissions &nbsp;</li><li>Generate custom reports &nbsp;</li><li>Print certificates of analysis &nbsp;</li><li>Remotely monitor and control the instrument from your PC &nbsp;</li></ul></li><li>Optional accessories: Bluetooth barcode reader, Bluetooth printer, Bluetooth GPS</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_3t_GOLDD_XRF_Analyzer_5_9e51a6a9ac.jpg" alt="Thermo Scientific™ Niton™ XL3t GOLDD+ XRF Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_3t_GOLDD_XRF_Analyzer_5_9e51a6a9ac.jpg 219w," sizes="100vw" width="650" height="464"><h3>📏 Specifications</h3><ul><li>Analytical Range: Up to 30 elements from Mg to U (varies by application)</li><li>Available Analytical Modes: Varies by application<ul><li>Alloy Modes: Metal Alloy, Electronics Alloy, Precious Metals</li><li>Bulk Modes: Soil, Mining, TestAll</li><li>Plastic Modes: RoHS Plastics, Toy and Consumer Goods, Plastics, TestAll, Painted Products</li><li>Custom Modes: Upon request</li></ul></li><li>Certifications/Compliance: CE, RoHS</li><li>Data Entry: Touch-screen keyboard, user-programmable pick lists, optional wireless remote barcode reader</li><li>Data Memory: 32MB internal system memory / 128 MB internal user storage</li><li>Data Storage: Internal &gt;10,000 readings with spectra</li><li>Data Transfer: USB, Bluetooth and RS-232 serial communication</li><li>Description: Niton XL3t GOLDD+ XRF Analyzer</li><li>Dimensions (L × W × H): 9.6 × 9.05 × 3.75 in. (244 × 230 × 95.5 mm)</li><li>Display Type: Tilting, color, touch-screen display</li><li>Height (English): 3.75 in.</li><li>Height (Metric): 95.5 mm</li><li>Item Description: XL3t GOLDD+ XRF Analyzer</li><li>Length (English): 9.6 in.</li><li>Length (Metric): 244 mm</li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Max. Power: 2W</li><li>Operating System: Ownership</li><li>Optional Accessories:<ul><li>3mm small-spot collimation</li><li>Portable test stand</li><li>Stationary (benchtop) test stand</li><li>Mobile test stand</li><li>Field Mate</li><li>Thermo Scientific™ Extend-a-Pole™</li><li>Welding mask</li><li>Thermo Scientific™ HotFoot™ hot surface adapter</li><li>Soil testing guard</li></ul></li><li>Power Consumption: 0 to 200 μA</li><li>Security Features: Password-protected user security</li><li>Standard Accessories:<ul><li>Integrated CCD camera for locating and storing images</li><li>Locking shielded carrying case</li><li>Shielded belt holster</li><li>Two lithium-ion battery packs</li><li>Spare battery pack</li><li>110/220 VAC battery charger/AC adaptor</li><li>PC connection cables (USB and RS-232)</li><li>Thermo Scientific™ Niton Data Transfer (NDT™) PC software</li><li>Safety lanyard</li><li>Check samples/standards</li></ul></li><li>System Electronics: 533 MHz ARM 11 CPU, 300 MHz dedicated DSP, 80 MHz ASICS DSP for signal processing</li><li>Tube Type: Ag anode 50 kV and 200 μA</li><li>Voltage: 6 to 50 kV</li><li>Weight (English): 3 lb.</li><li>Weight (Metric): 1.3 kg</li><li>Width (English): 9.05 in.</li><li>Width (Metric): 230 mm</li><li>Applications: Sample Identification, Positive Material Identification</li><li>Detector Type: Geometrically Optimized Large Area Drift Detector</li><li>Tube Voltage: 6 to 50 kV</li><li>Unit Size: Each</li></ul><h3>Which analyzer for your application?</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></div>

Thermo Scientific Niton XL2 100G General Metal Analyzer

Get immediate, nondestructive elemental analysis of alloy materials from titanium to nickel with the Thermo Scientific™ Niton™ XL2 100G General Metal Analyzer. 

<div><div><div><div><div>Get immediate, nondestructive elemental analysis of alloy materials from titanium to nickel with the Thermo Scientific™ Niton™ XL2 100G General Metal Analyzer. The XL2 100G analyzer is a practical, cost-effective solution that offers fast analysis for general alloy identification, basic fabrication, and scrap metal sorting.&nbsp;This high value, high performance analyzer features advanced electronics yet it is ruggedly built to withstand the harshest environments, in the field or on the shop floor.</div><div><h3>The value choice to ensure accuracy, precision, and ease of use:</h3><ul><li>Precise elemental analysis of alloy materials</li><li>Very easy to use – even by non-technical personnel</li><li>Ruggedly designed for the most challenging industrial environments, and sealed against moisture and dust</li><li>Completely nondestructive test</li><li>Ergonomically designed&nbsp;</li><li>Customizable menus with multiple language options and daylight-readable icons</li><li>Standard analytical range of more than 25 elements from sulfur to uranium.</li></ul></div></div><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XL_2_100_G_General_Metal_Analyzer_340e83faa3.jpg" alt="Thermo Scientific™ Niton™ XL2 100G General Metal Analyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XL_2_100_G_General_Metal_Analyzer_340e83faa3.jpg 156w," sizes="100vw" width="650" height="650"><h3>Specifications</h3><ul><li>Analytical Range: 25 elements from Ti to Bi</li><li>Available Analytical Modes: Alloy Modes: Metal Alloy</li><li>Certifications/Compliance: CE, RoHS</li><li>Data Entry:&nbsp;<ul><li>Touch-screen keyboard</li><li>User-programmable pick lists</li><li>Optional wireless remote barcode reader</li></ul></li><li>Data Storage: Internal &gt;10,000 readings with spectra</li><li>Data Transfer: USB, Bluetooth™, and RS-232 serial communication</li><li>Dimensions (L x W x H): 10.25 × 11 × 4 in. (256 × 275 × 100 mm)</li><li>Display Type: Fixed angle, color, touch-screen display</li><li>IP Rating: IP54 (splash and dust proof)</li><li>Licensing: Varies by region. Contact your local distributor.</li><li>Max. Power: 2W</li><li>Operating System: Ownership</li><li>Optional Accessories:&nbsp;<ul><li>Thermo Scientific™ portable test stand</li><li>Stationary (bench-top) stand</li><li>Mobile test stand</li></ul></li><li>Security Features: Password-protected user security</li><li>Standard Accessories:&nbsp;<ul><li>Locking shielded carrying case</li><li>Shielded belt holster</li><li>One 6-cell Li-ion battery pack</li><li>110/220 VAC battery charger/AC adaptor</li><li>PC connection cables (USB and RS-232)</li><li>Niton Data Transfer (NDT) PC software</li><li>Safety lanyard</li><li>Check samples/standards</li></ul></li><li>System Electronics:&nbsp;<ul><li>400 MHz ARM 11 CPU</li><li>300 MHz dedicated DSP</li><li>80 MHz ASICS DSP for signal processing</li><li>4096 channel MCA</li><li>64 MB internal system memory / 128 MB internal user storage</li></ul></li><li>Tube Type: Ag anode 38kV maximum, 80 μA maximum</li><li>Weight (English): 3 lbs 5.8 oz</li><li>Weight (Metric): 1.53 kg</li><li>Applications: Elemental Analysis</li><li>Detector Type: High-performance Semiconductor</li><li>Tube Voltage: 38 kV</li><li>Unit Size: Each</li></ul><h3>Which analyzer for your application?</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg" alt="Thermo Scientific™ Niton™ handheld XRF Analyzers - Niton handheld XRF analyzers are built for rugged use and deliver rapid, lab-quality results" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Niton_XRF_Analyzer_e7e7a24b10.jpg 145w," sizes="100vw" width="1024" height="1102"></div></div></div>

Products from Thermo Fisher Scientific - page 3

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