Analysis of characteristic flavor compounds in coffee peels subjected to different thermal processing treatments based on GC–IMS and HS-SPME–GC–MS combined with chemical pattern recognition

Forced degradation analysis of recombinant adeno-associated virus serotype 8 based on analytical anion exchange chromatography coupled to orthogonal characterization

Combining elemental analysis and molecular techniques to characterize Ancient Egyptian mummification balms

Food

Scientific article

Science and research

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Wiley Registry/NIST Mass Spectral Library 2023

Wiley Registry/NIST 2023 is the largest commercial MS library with 3+ million spectra (EI & MS/MS), ensuring reliable unknown compound identification across various applications.

<h4>Comprehensive Compound Coverage for Confident MS Results</h4>The Wiley Registry/NIST Mass Spectral Library 2023 offers unmatched compound coverage with over 3 million spectra (EI and MS/MS), making it the go-to resource for identifying unknowns in GC-MS and MS-MS workflows.Key benefits of the 2023 release:<ul><li>Broad compound range for targeted and non-targeted analysis</li><li>Expanded global patent coverage (USA, China, Japan, Europe)</li><li>Searchable metadata like structures, physical properties, and DOIs</li><li>Quality-checked data curated by experts</li><li>Segmented libraries for enhanced search performance</li><li>Comes with NIST 2023 Software (MS Search, AMDIS, MS Interpreter)</li><li>Now available via KnowItAll subscription for continuous updates</li></ul>New in 2023:<ul><li>74,000+ new compounds, 91,900+ new spectra</li><li>AI-RI values for EI data and major expansion of MS/MS entries</li><li>Spectra assigned a Quality Index for more precise filtering</li></ul>The Wiley Registry/NIST 2023 is compatible with most MS platforms. Learn more at <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/compatibility">sciencesolutions.wiley.com/compatibility</a>.

Wiley NIST/EPA/NIH Mass Spectral Library 2023

The 2023 NIST/EPA/NIH Mass Spectral Library is a major update from NIST's expert team, reflecting 40+ years of development. It’s an essential, trusted resource for accurate mass spectral analysis.

<h4>Boost Your MS Workflow with the NIST 2023 Mass Spectral Library</h4>The NIST/EPA/NIH Mass Spectral Library 2023 is a major update to one of the world’s most trusted MS databases. Developed by NIST's expert team over four decades, it remains a vital tool for GC-MS and MS/MS analysis.What's Included:<ul><li>EI Library: 394,000 spectra, 341,600 unique compounds, now with AI-RI values</li><li>MS/MS Libraries: 2.3M+ spectra, 51,500+ compounds, 399,000+ precursor ions</li><li>GC Retention Index Library: 491,700 RI values, 180,600 unique compounds</li><li>NIST Software: MS Search, AMDIS, MS Interpreter</li></ul>New in 2023:<ul><li>40,000+ new EI compounds and 43,000+ spectra added</li><li>MS/MS coverage expanded by 60% over 2020 release</li><li>Enhanced compatibility with most MS platforms via Wiley</li></ul>Even More with Wiley:<ul><li>Combine with the Wiley Registry 2023 for greater coverage</li><li>Add KnowItAll Software for advanced spectral analysis</li></ul>Compatible with most MS data systems. Learn more: <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/compatibility">sciencesolutions.wiley.com/compatibility</a>

ARC Polyarc System

A Breakthrough Innovation Revolutionizing GC/FID Technology. The Polyarc System is transforming the way scientists use gas chromatographs with Flame Ionization Detectors.

The Polyarc system has a catalytic microreactor that enhances new and existing gas chromatographs (GCs) with flame ionization detectors (FIDs) by converting all organic compounds to methane molecules prior to their detection by the FID. In doing so, the Polyarc system reduces the need to perform time-consuming calibrations by creating a uniform detector response for truly universal carbon detection.
The Polyarc system gives scientists the capability to determine purity, quantify unknowns, qualify products, investigate, improve development and more in a simple, fast and more economical way that is transforming the industry.
<blockquote>
Available for gas chromatographs (GC) <a href="https://gcms.labrulez.com/products?category=1&amp;manufacturerItems=10">Agilent</a> 5890, 6890, 7820, 7890, 8890, <a href="https://gcms.labrulez.com/products?category=1&amp;manufacturerItems=1">Shimadzu</a> 2030, <a href="https://gcms.labrulez.com/products?category=1&amp;manufacturerItems=3">Thermo Fisher</a>, Varian, Bruker a Scion GC.
</blockquote>
<h3>What is Polyarc?</h3>
The Polyarc is the next evolution of flame ionization detection (FID). The Polyarc converts the FID into a truly universal carbon detector using proprietary catalytic reactions that convert organic molecules to methane immediately prior to detection.
<h3>Why is it important?</h3>
The FID has two main challenges: lack of uniform response and low response to certain compounds. The Polyarc enhances your FID to solve these challenges by giving your FID a uniform response to nearly all organic molecules. The result is more accurate data, improved productivity, lab efficiencies, and the ability to detect more compounds.
<h3>How Does the Polyarc® System Work to Simplify and Improve GC/FID Quantification?</h3>
The Polyarc system has a catalytic microreactor that enhances GC/FIDs by converting all organic compounds to methane molecules prior to detection by the FID. The result?
A universal response for ALL organic molecules.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_Polyarc_FID_vs_FID_Response_Factors_0f9c958558/ARC-PolyarcFID-vs-FID-Response-Factors.jpg" alt="ARC: Comaprison of Polyarc/FID vs FID Response Factors.jpg"/>
<h3>The Polyarc System Features an Optimized Design and Seamless Integration</h3>
The Polyarc system is the first commercial technology of its kind. The device uses proprietary technologies including novel catalysts, a specially designed 3D-printed micro reactor, and fast seamless integration into existing equipment.
The optimized internal design and catalyst microstructure maintains separation performance and peak shape while increasing sensitivity and enabling accurate quantification without calibration standards.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_Optimalizovany_design_a_specialne_navrzeny_3_D_tisteny_mikroreaktor_Polyarc_70ccedc41e/ARC-Optimalizovany-design-a-specialne-navrzeny-3D-tisteny-mikroreaktor-Polyarc.jpg" alt="ARC: Specially designed 3D-printed micro reactor Polyarc"/>
<h3>Perform Cutting-Edge Chromatography on Any Organic Compound with a Polyarc® System</h3>
Realize a greater breadth of analysis with improved detection of compounds previously invisible or with an extremely low sensitivity by gas chromatography using FID only — while reducing the need for time intensive calibration.
The careful selection and robust catalyst design enables the analysis of a wide variety of compounds including a range of heteroatoms, compounds of various sizes, and samples containing common catalytic poisons (e.g., S).
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_Analyza_siroke_skaly_sloucenin_pomoci_Polyarc_systemu_3e18241358/ARC-Analyza-siroke-skaly-sloucenin-pomoci-Polyarc-systemu.png" alt="ARC: Polyarc system enables the analysis of a wide variety of compounds"/>
<h3>How Does the Polyarc System Compare to a Methanizer?</h3>
A conventional methanizer converts CO and CO₂ to methane, allowing low level FID detection of CO and CO₂. The significant advantage of the Polyarc system is that it converts all compounds to methane, allowing not only for the detection of CO and CO₂ , but also millions of other organic compounds.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_Srovnani_systemu_Polyarc_s_metanizerem_7df16e09c7/ARC-Srovnani-systemu-Polyarc-s-metanizerem.jpg" alt="ARC: Comparison of the Polyarc System with a metanizer"/>

ARC Jetanizer (Methanizer)

The Jetanizer is the easiest and most robust methanizer.

<h3>What is Jetanizer™?</h3>
The Jetanizer is the easiest and most robust methanizer. A methanizer is a chemical reactor that converts carbon dioxide and carbon monoxide to methane to enable sensitive detection by a flame ionization detector (FID) from &lt;20 ppb to 100%!
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_Analyza_CO_2_od_1ppm_do_100_s_pouzitim_GC_jetanizeru_FID_9c922be2e9/ARC-Analyza-CO2-od-1ppm-do-100percent-s-pouzitim-GC-jetanizeru-FID.jpg" alt="ARC: CO₂ analysis from 1ppm to 100% with GC/Jetanizer/FID"/>
<h3>Why is it important?</h3>
<h4>Low-level detection of CO and CO₂ is important in:</h4>
<ul>
<li>catalysis </li>
<li>hydrogen (H₂) purity analysis </li>
<li>dissolved gas analysis (DGA)</li>
<li>greenhouse gas (GHG) analysis, </li>
<li>transformer oil gas analysis (TOGA)</li>
<li>ethylene/propylene monomers analysis </li>
<li>safe entry analysis, and more</li>
</ul>
Traditionally, large nickel-catalyst-filled tube methanizers are used, however, they are prone to frequent failures, and they are difficult and time consuming to operate and maintain. 
<blockquote>
Legacy nickel catalyst methanizers take 2-6 hours to install and replace. Jetanizers take &lt;5 minutes.
</blockquote>
ARC’s Jetanizer solves these challenges by improving response, robustness and ease of installation, by incorporating state-of-the-art catalysts into an FID jet. Moreover, the Jetanizer enables low level &lt;1 ppm formaldehyde analysis by GC avoiding the pitfalls of HPLC analysis of formaldehyde.
<blockquote>
For use with these GC models: <a href="https://gcms.labrulez.com/products?category=1&amp;manufacturerItems=10">Agilent 5890, 6890, 7890, 8890, Intuvo</a>, <a href="https://gcms.labrulez.com/products?category=1&amp;manufacturerItems=1">Shimadzu 2010, 2030 GC</a>.
</blockquote>
<h3>Benefits over Traditional Methanizers</h3>
<ul>
<li>Lower up-front cost</li>
<li>No extra plumbing: minimize fittings and leaks</li>
<li>No extra heater or controller: utilizes heat from FID</li>
<li>FAST installation: Less than 5 minutes</li>
<li>Ability to be used with formaldehyde</li>
<li>Higher sulfur tolerance</li>
<li>Higher catalytic activity = larger linear dynamic range</li>
<li>Free up space on the GC</li>
<li>No toxic metals: The Jetanizer™ does not contain nickel catalysts</li>
</ul>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_Kalibrace_analyzy_CO_2_s_pouzitim_GC_jetanizeru_FID_2f0b6171fc/ARC-Kalibrace-analyzy-CO2-s-pouzitim-GC-jetanizeru-FID.jpg" alt="ARC: CO₂ analysis calibration with GC/Jetanizer/FID"/>

ARC GCxGC Xpansion

ARC’s simple stop-flow modulator can be installed in minutes and turn any GC into a powerful multi-dimensional separation machine. ARC’s modulator emphasizes robustness, simplicity, and ease of use to allow anyone from a novice GC user to a veteran expert to generate valuable chemical data on the most complex samples. 

<h3>No-fuss GCxGC solution</h3>
This affordable package includes free, open-source software (visualization only), and ARC’s lifetime support. For power users we offer GC Image software. 
<h3>Why choose us?</h3>
<ul>
<li>Affordable</li>
<li>Robust design</li>
<li>Simple and easy self-installation or professional installation</li>
<li>Dramatically increased peak capacity</li>
<li>Easily switch between 1D and 2D GC</li>
<li><a href="https://www.activatedresearch.com/gcxgc_vis/">Free visualization software</a></li>
</ul>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_ARC_G_Cx_GC_Xpansion_9536cf0985/ARC-ARC-GCxGC-Xpansion.jpg" alt="ARC: ARC GCxGC Xpansion solution"/>
<h3>Why should I use GCxGC?</h3>
The separation of compounds by gas chromatography is typically performed using a single analytical column. As samples become more complex, it can become difficult to separate all the compounds from each other and they can start to overlap, or co-elute. Longer or narrower columns can be used to increase resolving power, but with diminishing returns.
Comprehensive two-dimensional GC, or GCxGC, drastically increases separation power by adding a second analytical column after the first column. A modulator placed between the two columns pulses the analytes from the first column onto the second column. When the columns are orthogonal in separation power, this technique can result in an order of magnitude increase in the number of analytes that can be detected.
ARC’s solution takes advantage of stop-flow modulation to make GCxGC an attainable configuration for any analytical laboratory. It involves continually sampling the effluent from the first column into an accumulator tube and re-injecting it onto a second, smaller column with orthogonal separation. This second separation happens in the time it takes to accumulate the next sample. The pulse time is known as the modulation time.

ARC Precision Split

ARC’s PrecisionSplit device allows scientists and chromatographers to take advantage of the quantitative power of the Polyarc/FID in combination with the mass identification power of the mass spectrometer, all in the same injection in real time.

<h3>Why does my MS need an FID?</h3>
A mass spectrometer (MS) provides valuable qualitative data, but poses several challenges to accurate quantification. Adding a flame ionization detector (FID) in parallel with the MS gives complementary quantitative carbon concentrations with minimal extra effort or equipment. We believe every MS needs an FID companion for quantitative analysis, especially for non-targeted analysis or tentatively identified compounds where quantification is desired.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_Precision_Split_6271ed1240/ARC-Precision-Split.jpg" alt="ARC: Precision Split"/>
<h3>The benefits of a MS/FID split:</h3>
<ul>
<li>Virtually eliminate response factor variability</li>
<li>Quantify accurately (better linearity, more consistent response, fewer calibration errors)</li>
<li>Improve sensitivity for poor ionizers with the FID</li>
<li>Save your source!</li>
</ul>
<h3>The Data</h3>
Response factor (RF) variation in the mass spectrometer (i.e., the relative response of the MS to different chemicals) can lead to significant errors in quantification. Two compounds that have the same response/area in the MS can have concentrations that differ more than 100-fold (see <a href="https://www.sciencedirect.com/science/article/pii/S0731708520304283">Jordi et al.</a>). 
As you can see below, the Polyarc/FID split can reduce this response factor variation so that accurate quantification of tentatively identified compounds is possible.
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_Variance_RF_u_MS_detektoru_8e02773edc/ARC-Variance-RF-u-MS-detektoru.jpg" alt="ARC: RF variation with MS"/>
<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ARC_Variance_RF_s_Polyarc_FID_splittrem_ca7def3cb3/ARC-Variance-RF-s-Polyarc-FID-splittrem.jpg" alt="ARC: RF variation with Polyarc/FID split"/>

Products distributed by LabRulez - page 16

Related content

Combining elemental analysis and molecular techniques to characterize Ancient Egyptian mummification balms

Forced degradation analysis of recombinant adeno-associated virus serotype 8 based on analytical anion exchange chromatography coupled to orthogonal characterization

Analysis of characteristic flavor compounds in coffee peels subjected to different thermal processing treatments based on GC–IMS and HS-SPME–GC–MS combined with chemical pattern recognition