Post-translational modifications (PTMs) are where so much of biology’s complexity lives, but they are also some of the hardest molecular features to analyze with confidence. Phosphorylation, asymmetric dimethylarginine (ADMA), and O-GlcNAcylation (O-GlcNAc) often occur at low abundance, can be highly labile, and frequently require precise site localization to understand their biological meaning. This<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/tn_004377_ov_phosphorylation_ptm_etd_excedion_pro_tn004377_na_en_71f681655f.pdf"> technical note </a>shows how the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1958">Thermo Scientific Orbitrap Excedion Pro Hybrid Mass Spectrometer</a> helps address those challenges by combining fast, sensitive performance with complementary <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/7217">HCD and EThcD fragmentation</a> workflows.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Phosphorylation_ADMA_and_O_Glc_N_Ac_Analysis_on_the_Orbitrap_Excedion_Pro_Mass_Spectrometer_d24a5de98e.jpg" alt="Thermo Fisher Scientific: Phosphorylation, ADMA, and O-GlcNAc Analysis on the Orbitrap Excedion Pro Mass Spectrometer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Phosphorylation_ADMA_and_O_Glc_N_Ac_Analysis_on_the_Orbitrap_Excedion_Pro_Mass_Spectrometer_d24a5de98e.jpg 245w," sizes="100vw" width="1024" height="512">Using enriched PTM samples and automated data-dependent acquisition, the study demonstrates that the Orbitrap Excedion Pro MS can deliver both depth and confidence across multiple PTM classes. For phosphorylation analysis, the platform identified 5,892 unique phosphosites from IMAC-enriched samples and 2,941 unique phosphotyrosine sites after phosphotyrosine enrichment, highlighting strong performance for both broad and highly targeted signaling studies. Just as importantly, the data show that HCD and EThcD provide complementary value, with each fragmentation method contributing unique site identifications and helping resolve ambiguous assignments.The note also highlights the value of EThcD for more analytically demanding PTMs. In ADMA-enriched samples, EThcD delivered more ADMA peptide-spectrum matches and more unique modified peptides than HCD, supporting improved confidence in site characterization. For O-glycopeptides, the Orbitrap Excedion Pro MS uses an intelligent HCD-product-dependent-EThcD strategy that triggers EThcD only when oxonium ions are detected, improving productivity while preserving the fragmentation detail needed for confident glycosite localization.Overall, this technical note shows how Orbitrap Excedion Pro MS enables researchers to go deeper into PTM biology with greater sensitivity, better site confidence, and smarter acquisition. For scientists studying signaling, regulation, and disease mechanisms, it presents a powerful approach for expanding PTM coverage without compromising analytical rigor.<blockquote><h5><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/tn_004377_ov_phosphorylation_ptm_etd_excedion_pro_tn004377_na_en_71f681655f.pdf">Download the technical note "Advancing phosphorylation, ADMA, and O-GlcNAc PTM analysis with HCD and EThcD on the Orbitrap Excedion Pro mass spectrometer"</a></h5></blockquote>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#PTM #OrbitrapExcedionPro #glycosylation #phosphorylation

Phosphorylation, ADMA, and O-GlcNAc Analysis on the Orbitrap Excedion Pro Mass Spectrometer

<h4>Latest edition of the Wiley Registry/NIST Mass Spectral Library for leading pharmaceutical, environmental, and forensic laboratories worldwide expands coverage to more than 1.2 million spectra</h4>Wiley, a global leader in authoritative content and research intelligence, today released the new edition of the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2591">Wiley Registry/NIST Mass Spectral Library</a>, a reference database that combines two essential mass spectrometry references in a single, integrated collection, giving scientists the full depth of both to identify unknown chemical compounds.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_Registry_NIST_EI_Mass_Spectral_Library_2026_4d3c8f440f.jpg" alt="Wiley: Wiley Registry/NIST EI Mass Spectral Library 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Wiley_Registry_NIST_EI_Mass_Spectral_Library_2026_4d3c8f440f.jpg 110w," sizes="100vw" width="1524" height="2161">For years, laboratories doing GC-MS analysis have relied on Wiley’s renowned <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/887">Wiley Registry of Mass Spectral Data</a> and the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2461">NIST/EPA/NIH EI Mass Spectral Library</a> from the U.S. government’s National Institute of Standards and Technology (NIST) to power their analytical workflows. These two respected references are united in this database, one of the most comprehensive resources of its kind.The new 2026 edition updates the collection, adding tens of thousands of newly validated compounds across both libraries and bringing the total to more than 1.2 million electron ionization (EI) mass spectra—unique chemical “signatures” used to identify substances.The Wiley Registry/NIST Mass Spectral Library is part of Wiley’s growing portfolio of scientific data and research intelligence solutions, which spans spectral databases, chemistry and materials literature, and analytical tools supporting researchers from discovery through applied outcomes.Wiley’s spectral database solutions are trusted by leading pharmaceutical, environmental, and forensic laboratories worldwide, reflecting Wiley’s mission to transform knowledge into actionable intelligence that helps researchers make confident, high-stakes decisions.<blockquote>“When a scientist runs a sample through a mass spectrometer, the results are only as good as the reference data behind them,” said Armughan Rafat, Wiley senior vice president and chief AI &amp; data analytics officer. “By uniting the Wiley Registry and the NIST Library in a single resource, we deliver the breadth, quality, and validation scientists need to identify unknown compounds faster and with confidence.”</blockquote>Available in the most common instrumentation manufacturer formats, the library supports high-confidence analysis across GC-MS workflows.<h4>Spectral Databases</h4>Spectral databases contain unique molecular “fingerprints” of substances captured through analytical techniques such as infrared (IR), mass spectrometry (MS), nuclear magnetic resonance (NMR), and Raman spectroscopy. By comparing experimental spectra against validated reference data, researchers can accurately identify unknown compounds across a wide range of applications. &nbsp;<h4>About Wiley</h4>Wiley is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what’s possible in science and learning.&nbsp;

Wiley Releases Database Combining Two of the World’s Most Trusted Chemical Identification Resources

The countdown is almost over. In just one week, the international chromatography community will meet in Prague for the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/events/644">35th International Symposium on Chromatography (ISC 2026)</a>, taking place from September 6–10, 2026. Whether your registration has been confirmed for months or you are still deciding whether to join, now is the time to finalize your plans. Here is what you need to know before ISC 2026 begins.<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/companies/314">ISC</a> is the oldest conference series dedicated to separation science, with symposia organized since 1956. This September, the Prague Congress Centre will welcome researchers, industry experts, instrument manufacturers, young scientists, and other specialists for five days of chromatography and separation science, covering everything from fundamental research to pharmaceutical, environmental, food, health, and omics applications.But before the scientific sessions begin, there are a few practical details worth checking.<h4>ISC officially starts on September 6 – but activities begin a day earlier</h4>The official dates for ISC 2026 are Sunday, September 6 through Thursday, September 10, but for some participants the conference starts already on Saturday, September 5.The first Short Courses are scheduled for Saturday (<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/6770">SC 1 – Modern HPLC Separation in Theory and Practice</a> and <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7312">SC 2 – mzmine for LC-MS data analysis</a>), with additional courses continuing on Sunday morning and afternoon. If you have registered for a Short Course, make sure to check its exact date and starting time before arranging your journey to Prague.Sunday then marks the official opening of ISC 2026, with the Opening Ceremony, Award Ceremony, <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7361">plenary lectures</a>, and Welcome Reception introducing delegates to the week ahead.<h4>Haven’t registered yet? You can still join ISC 2026</h4>Missed the late-registration deadline? It is still possible to attend.Onsite registration has been available since August 26, 2026, giving last-minute participants another opportunity to join the symposium. Current onsite registration fees are:<ul><li>Industry: €1,150</li><li>Academic: €890</li><li>Student: €390</li><li>Short Courses: €270</li></ul>The Short Course fee covers participation in up to three Short Courses.One practical point for last-minute registration: bank-transfer payments closed on August 19, so only card payments are now accepted.Full registration includes access to oral and poster sessions, the exhibition, the Sunday Welcome Reception, scheduled lunches and coffee breaks, the electronic Book of Abstracts, and a Prague public transportation pass.<h4>Where is ISC 2026 and how do you get there?</h4>ISC 2026 will take place at the:Prague Congress Centre<ul><li>5. května 65</li><li>140 21 Prague 4</li><li>Czech Republic</li></ul>The venue is particularly easy to reach by public transport. It is located directly on Prague’s Metro Line C at Vyšehrad station, just around five minutes by metro from Muzeum station in the city centre.The Prague Congress Centre brings the lecture halls, exhibition spaces, meeting rooms, and other conference facilities together in one venue, making it easy to move between scientific sessions, posters, industry activities, and the exhibition throughout the day.And since full conference registration includes public transportation in Prague, getting around the city during ISC should be straightforward.<h4>When can you pick up your conference materials?</h4>The registration desk will already be open during the Short Courses and will remain available throughout the symposium.Registration opening hours:<ul><li>Saturday, September 5: 8:30–17:00</li><li>Sunday, September 6: 7:30–19:00</li><li>Monday, September 7: 7:30–18:00</li><li>Tuesday, September 8: 7:30–19:00</li><li>Wednesday, September 9: 8:00–18:00</li><li>Thursday, September 10: 8:30–14:30</li></ul>If you are arriving in Prague on Sunday, allowing some extra time for registration before the Opening Ceremony will make the start of the conference considerably more relaxed.<h4>Now is the time to build your personal ISC program</h4>With several parallel sessions running throughout the week, trying to decide where to go only after arriving at the venue may mean missing something important.The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7477">main scientific program</a> is organized around three broad areas:<ul><li>Fundamentals</li><li>Bioanalysis and omics applications</li><li>Hyphenated techniques</li></ul>These are complemented by <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7280">Tutorials </a>+ Young Speakers, plenary and invited lectures, poster sessions, the international exhibition, vendor seminars, and industry-focused activities.Before leaving for Prague, take another look at the Interactive Program and mark the lectures, posters, and other activities that are most relevant to you. If you are presenting your own work, this is also the right time to double-check your assigned session, room, and presentation time.And don’t focus only on the oral program. Poster sessions and exhibition breaks are among the best opportunities to discuss new research directly with authors, meet instrument and technology specialists, and make new contacts.<h4>Don’t overlook the vendor seminars and industry program</h4>ISC 2026 is not limited to academic presentations. The conference also includes an extensive industry component, with activities covering current challenges in separation science and practical applications of new analytical technologies.During the lunchtime sessions, participants can attend <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7736">vendor seminars</a> presented by companies including Avantor, Shimadzu, Advanced Materials Technology, Restek, and Thermo Fisher Scientific. Topics range from stationary-phase selectivity and chromatographic modelling to HPLC and LC-MS column technologies and advanced characterization of biotherapeutics.The conference also includes dedicated <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7777">Industry Activities</a> from Monday through Wednesday, bringing together academic and industrial perspectives on topics relevant to analytical laboratories and the future of separation science. One of the discussions, for example, will examine how education in separation science can better reflect the skills required by modern industry, while another will focus on sustainability and the practical implementation of greener analytical workflows.On Wednesday, participants can also join the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7801">Publishing Workshop</a>, another activity worth adding to the schedule if scientific publishing is part of your work.<h4>Test your chromatography knowledge at the ISC Quiz</h4>Not every session needs to be completely serious.On Tuesday, September 8 from 18:30 to 19:30, ISC will host an interactive Chromatography Quiz, combining practical questions, chromatography fundamentals, unusual facts, and lighter challenges.There is no advance registration required. Any registered conference participant can join, but remember to bring a smartphone—the quiz uses live participation through a QR code.Results will be scored in real time, and prizes will be awarded to the top three participants.<h4>Start networking from the first evening</h4>The scientific program may be the main reason to attend ISC, but the conversations between sessions can be equally valuable.The first major networking opportunity comes immediately on Sunday.The Welcome Reception will take place on September 6 from 18:30 to 20:00 in the second-floor foyer of the Prague Congress Centre. It is open to registered participants and accompanying persons and includes a light buffet and drinks.As it takes place immediately after the opening program, it is an ideal opportunity to reconnect with colleagues, meet new contacts, and start conversations before the full parallel scientific program begins on Monday.Another social highlight will be the Gala Dinner on Wednesday, September 9 from 19:00 to midnight at the National House Vinohrady.The Gala Dinner requires a separate €100 ticket, is not included in the standard registration fee, and has a smart-casual dress code. Participants should also note that transportation to and from the venue is not organized by the conference.<h4>And perhaps leave a little time for Prague</h4>A conference schedule can fill up quickly, but ISC 2026 is taking place in one of Europe’s most walkable cities.If you find some free time between sessions, Vyšehrad is only about a 10-minute walk from the Prague Congress Centre and offers panoramic views across Prague and the Vltava River. It is an easy option for a short walk without travelling back into the historic city centre.See you at ISC 2026 in Prague!

ISC 2026 Starts in One Week: What You Need to Know

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Thermo Fisher Scientific

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

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Wiley

Watrex Streamline™ P1 HPLC Pump, Stainless Steel

The Watrex Streamline™ P1 pump is a versatile and powerful dual-piston HPLC pump.

Streamline P1 pump, stainless steel fully meets the demanding requirements for HPLC pumps and can be combined seamlessly with HPLC detectors and instruments from other manufacturers.<blockquote>Price 4 935 € ex VAT</blockquote>In the analytical version of the pump, the flow rate range from 0.001 ml/min to 10 ml/min is adjustable in 1 ul increments with a maximum working pressure of 42 MPa (6,000 psi). Flow rate adjustment accuracy is ±1% and flow rate variation is better than ±0.1%. The pump’s extremely smooth flow profile is ensured by an efficient pulse damper and optimized cam shape.A unique feature is the active piston and seal rinse, which prevents crystallization of buffers. A touch screen display on the front panel allows intuitive control of the pump.The display shows the flow rate, the current pressure and the pump is equipped with pressure limits. A PRIME function is also directly available for flushing at increased flow rates.<figure class="image"><img style="aspect-ratio:611/408;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Streamline_P1_Pump_Stainless_Steel_23a7bf9f11.jpg" alt="Watrex: Streamline™ P1 Pump, Stainless Steel." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_Streamline_P1_Pump_Stainless_Steel_23a7bf9f11.jpg 234w," sizes="100vw" width="611" height="408"></figure><h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0.001 to 10.000 mL/min</li><li>Pressure: 0 to 6,000 psi (42 MPa)</li><li>Flow precision: &gt; 0.2% RSD</li><li>Flow accuracy: ± 1 % @ 1mL/min and 7 MPa,</li><li>Pressure accuracy: ± 2% of full-scale, with 80:20 H2O/IPA @ 7 MPa</li><li>Pulsation: ± 0.5 % @ 1mL/min and 7 MPa</li><li>Remote inputs: USB</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/isocratic-pumps/streamline-p1-pump-stainless-steel/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

SIELC Alltesta Mini Syringe Pump

Alltesta™ Ultra High Pressure Mini Syringe Pump is designed to produce a steady, high pressure, pulsation-free flow, so there is no need for bulky dampeners, mixers, and precision check valve arrangements.

Alltesta™ Ultra High Pressure Mini Syringe Pump is designed to produce a steady, high pressure, pulsation-free flow, so there is no need for bulky dampeners, mixers, and precision check valve arrangements. It can refill prior to each run in less than a minute, and can produce flow rates from as low 1 μL/min to as fast as 4000 μL/min with pressure up to 4000 psi (285 bar).
The Mini Syringe Pump allows for several communication options via its USB/Serial port. Just like the rest of our Alltesta™ line of devices, our serial protocol allows to control and automate every function of the device. We also provide free Windows-based software allowing full control of the device.
<h4>Specifications</h4>
<ul>
<li>Syringe volume: 5.8 mL</li>
<li>Power Requirements 24 VDC</li>
<li>Current Requirements Up to 1.5 A</li>
<li>Dimensions (WHL) 63x167x128 mm / 2.48×6.57×5.04 in</li>
<li>Weight 1.65 kg / 3.7 lb</li>
<li>Flow Rate Range 0.001 to 4 mL/min</li>
<li>Speed Accuracy 1% of full-scale</li>
<li>Linearity Full Range 0.001 to 4.0 mL/min</li>
<li>Pressure 4000 psi (285 bar) continuous</li>
<li>Pressure accuracy ±1 psi</li>
<li>Operating Temperature 0 to 40° C, non-condensing</li>
<li>Inlet/Outlet Thread 10-32 UNF compression type</li>
<li>Materials in contact with liquid SS316, PTFE, PEEK</li>
<li>Communication USB virtual serial port</li>
</ul>
<h4>Software</h4>
The Mini Syringe Pump can be controlled:
<ul>
<li>directly through your software via serial commands (Alltesta™ protocol available upon request, please contact us at support@sielc.com),</li>
<li>remotely through our cloud software (as a part of <a href="https://lcms.labrulez.com/products/1242">Alltesta™ Gradient Automated Analyzer</a> and <a href="https://lcms.labrulez.com/products/1243">Alltesta™ Cromite Analyzer</a>.),</li>
<li>directly via our demo software, allowing to learn the whole functionality of the unit (<a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Pump_Control_Windows_10.zip">Windows 10, 32/64bit</a>, 5Mb; <a href="https://sielc.com/wp-content/uploads/2022/12/Alltesta_Pump_Control_Windows_7.zip">Windows 7, 32/64bit</a>, 126Mb)</li>
</ul>
Serial Communication Drivers are available <a href="https://ftdichip.com/drivers/vcp-drivers/">here</a>.
<h4>Available Custom Options</h4>
Metal-free version of the pump includes no metal contact pump head and can be operated up to 4000 psi.

Watrex Streamline™ P1 HPLC Pump, PEEK

Streamline P1 pump, PEEK fully meets the demanding requirements for HPLC pumps and can be combined seamlessly with HPLC detectors and instruments from other manufacturers.<blockquote>Price 4 935 € ex VAT</blockquote>In the analytical version of the pump, the flow rate range from 0.001 ml/min to 10 ml/min is adjustable in 1 ul increments with a maximum working pressure of 42 MPa (6,000 psi). Flow rate adjustment accuracy is ±1% and flow rate variation is better than ±0.1%. The pump’s extremely smooth flow profile is ensured by an efficient pulse damper and optimized cam shape.A unique feature is the active piston and seal rinse, which prevents crystallization of buffers. A touch screen display on the front panel allows intuitive control of the pump.The display shows the flow rate, the current pressure and the pump is equipped with pressure limits. A PRIME function is also directly available for flushing at increased flow rates.<figure class="image"><img style="aspect-ratio:1024/768;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Streamline_P1_Pump_PEEK_dbc4418900.jpg" alt="Watrex: Streamline™ P1 Pump, PEEK." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_Streamline_P1_Pump_PEEK_dbc4418900.jpg 208w," sizes="100vw" width="1024" height="768"></figure><h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0.001 to 10.000 mL/min</li><li>Pressure: 0 to 6,000 psi (42 MPa)</li><li>Flow precision: &gt; 0.2% RSD</li><li>Flow accuracy: ± 1 % @ 1mL/min and 7 MPa,</li><li>Pressure accuracy: ± 2% of full-scale, with 80:20 H2O/IPA @ 7 MPa</li><li>Pulsation: ± 0.5 % @ 1mL/min and 7 MPa</li><li>Remote inputs: USB</li></ul>

Watrex Streamline™ P1q HPLC Pump, PEEK

Streamline P1g is a PEEK quaternary gradient pump that offers low pressure mixing of up to four mobile phase components with better than 1% accuracy.

Streamline P1g is a PEEK quaternary gradient pump that offers low pressure mixing of up to four mobile phase components with better than 1% accuracy.<blockquote>Price 10 572 € ex VAT</blockquote>An integrated four-channel degasser ensures trouble-free mixing and pumping of the mobile phase. In the analytical version of the pump, the flow rate range from 0.001 ml/min to 10 ml/min is adjustable to 0.001 ml/min with a maximum working pressure of&nbsp;35 MPa (5,000 psi). Flow rate adjustment accuracy is ±1% and flow rate variation is better than ±0.1%. A unique feature is an active piston and seal rinse that prevents crystallization of buffers.&nbsp;A touch screen display on the front panel allows intuitive control of the pump. The display shows flow rate and pumped composition. Pump control and gradient programming is provided by a software module in <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity software</a> (DataApex). The PRIME function is also directly available for flushing at increased flow rates.<figure class="image"><img style="aspect-ratio:800/600;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Streamline_P1q_HPLC_Pump_PEEK_c4ca5fdaa4.jpg" alt="Watrex: Streamline™ P1q HPLC Pump, PEEK" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_Streamline_P1q_HPLC_Pump_PEEK_c4ca5fdaa4.jpg 208w," sizes="100vw" width="800" height="600"></figure><h3>PUMP FEATURES</h3><ul><li>Each pump has a single stepper motor driven, dual head positive displacement pump (pump heads 180° out of phase)</li><li>PEEK pump heads and fluid path</li><li>Incorporates a diaphragm-type pulse damper, which reduces pulsation in the system by as much as 90% and includes an isolated pressure transducer (i.e., the transducer adds no dead volume).</li><li>Ruby/Sapphire Check Valves (1/16” ball)</li><li>Front panel flow adjustment in 0.001 mL/min increments</li><li>Upper and Lower Pressure Limits: Automatically turns the pump OFF if the system pressure exceeds the maximum pressure limit, or drops below minimum pressure limit</li><li>Microprocessor advanced control with advanced pre-compression algorithm and user calibration feature</li><li>Back panel USB communications port for complete control and status monitoring; Clarity Driver available</li><li>Automatic piston wash (self-flush)</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0.001 ml/min – 10 ml/min with step 0.001 ml/min</li><li>Pressure: 35 MPa/5000 psi</li><li>Pulsation: ± 1% @ from 7 MPa to 42 MPa</li><li>Pressure Accuracy: ± 2% of full-scale, with IPA</li><li>Flow Accuracy:&nbsp;better than ± 1% @ 10mL/min</li><li>Flow Precision: better then 0.1% RSD or 0.2 min SD, whichever is greater, across the full flow range, 20 MPa, with degassed methanol</li><li>Gradient Accuracy:&nbsp;1 % (between 10% and 90% mixing ratios)</li><li>Remote control: USB</li><li>I/O connector:&nbsp;Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/gradient-pumps/streamline-p1q-pump-peek/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex Streamline™ P1q HPLC Pump, Stainless Steel

Streamline P1g is a stainless steel quaternary gradient pump that offers low pressure mixing of up to four mobile phase components with better than 1% accuracy.

Streamline P1g is a stainless steel quaternary gradient pump that offers low pressure mixing of up to four mobile phase components with better than 1% accuracy.<blockquote>Price 10 572 € ex VAT</blockquote>An integrated four-channel degasser ensures trouble-free mixing and pumping of the mobile phase. In the analytical version of the pump, the flow rate range from 0.001 ml/min to 10 ml/min is adjustable to 0.001 ml/min with a maximum working pressure of 42 MPa (6,000 psi). Flow rate adjustment accuracy is ±1% and flow rate variation is better than ±0.1%. A unique feature is an active piston and seal rinse that prevents crystallization of buffers.A touch screen display on the front panel allows intuitive control of the pump. The display shows flow rate and pumped composition. Pump control and gradient programming is provided by a software module in <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999">Clarity software</a> (DataApex). The PRIME function is also directly available for flushing at increased flow rates.<figure class="image"><img style="aspect-ratio:800/600;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Streamline_P1q_HPLC_Pump_PEEK_c4ca5fdaa4.jpg" alt="Watrex: Streamline™ P1q HPLC Pump, Stainless Steel" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_Streamline_P1q_HPLC_Pump_PEEK_c4ca5fdaa4.jpg 208w," sizes="100vw" width="800" height="600"></figure><h3>PUMP FEATURES</h3><ul><li>Each pump has a single stepper motor driven, dual head positive displacement pump (pump heads 180° out of phase)</li><li>316 Stainless Steel pump heads and fluid path</li><li>Incorporates a diaphragm-type pulse damper, which reduces pulsation in the system by as much as 90% and includes an isolated pressure transducer (i.e., the transducer adds no dead volume).</li><li>Ruby/Sapphire Check Valves (1/16” ball)</li><li>Front panel flow adjustment in 0.001 mL/min increments</li><li>Upper and Lower Pressure Limits: Automatically turns the pump OFF if the system pressure exceeds the maximum pressure limit, or drops below minimum pressure limit</li><li>Microprocessor advanced control with advanced pre-compression algorithm and user calibration feature</li><li>Back panel USB communications port for complete control and status monitoring; Clarity Driver available</li><li>Automatic piston wash (self-flush)</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0.001 ml/min – 10 ml/min with step 0.001 ml/min</li><li>Pressure: 42 MPa/6000 psi</li><li>Pulsation: ± 1% @ from 7 MPa to 42 MPa</li><li>Pressure Accuracy: ± 2% of full-scale, with IPA</li><li>Flow Accuracy:&nbsp;better than ± 1% @ 10mL/min</li><li>Flow Precision: better then 0.1% RSD or 0.2 min SD, whichever is greater, across the full flow range, 20 MPa, with degassed methanol</li><li>Gradient Accuracy:&nbsp;1 % (between 10% and 90% mixing ratios)</li><li>Remote control: USB</li><li>I/O connector:&nbsp;Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/gradient-pumps/streamline-p1q-pump-stainless-steel/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex P102 HPLC pump, PEEK, biocompatible

Watrex P102 high performance liquid chromatography (HPLC) pump is designed to be a reliable component within a basic analytical or sophisticated research instruments.

Watrex P102 high performance liquid chromatography (HPLC) pump is designed to be a reliable component within a basic analytical or sophisticated research instruments.<blockquote>Price: 4 290<bdi>&nbsp;€ ex VAT</bdi></blockquote>While ideal for HPLC applications, the Model P102 pump is also useful as a metering pump for general laboratory or industrial use. The pump features dual self flushing pump heads with overlapping cams for reduced pulsation.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_P102_HPLC_pump_PEEK_5321aceaa0.jpg" alt="Watrex: P102 HPLC pump, PEEK" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_P102_HPLC_pump_PEEK_5321aceaa0.jpg 208w," sizes="100vw" width="1024" height="768"><h3>KEY FEATURES</h3>Double Piston Design: The double piston design ensures exceptional accuracy and precision in the delivery of solvents, making it ideal for applications that demand the utmost reliability.Wide range of operating conditions: With a wide range of flow rates, from the minutest quantities to larger volumes, our HPLC pump adapts to your diverse experimental needs without compromising precision. Handle high-pressure applications with confidence. Our pump delivers a maximum pressure of&nbsp;35 MPa, ensuring efficiency and reliability in even the most challenging chromatographic separations.Stainless Steel or PEEK Versions: Choose the material that suits your needs. Opt for the durability of stainless steel or the biocompatible advantages of PEEK. Both versions maintain high chemical resistance, making them suitable for a diverse range of chromatographic solvents.Efficient Pulse Dampener: Our integrated pulse dampener minimizes pressure fluctuations, ensuring a smooth and controlled flow. Experience enhanced separation quality and purity, thanks to the efficient dampening of pulsations.Versatile Applications: Whether you’re conducting routine analytical experiments or pushing the boundaries of chromatographic research, our pump caters to a wide array of applications, ensuring versatility in your lab.Demanding Dosing Applications: Excel in applications that demand precise and stable dosing. Achieve a stable jet stream for your research experiments, ensuring accuracy and reliability in every sampling.High-Quality Construction: Crafted with durability in mind, our pump is built to withstand the rigors of daily laboratory use. The robust construction ensures longevity and reliability.Chemical Compatibility: The pump is designed to handle a variety of solvents with ease, providing excellent chemical compatibility. This feature is crucial for researchers working with diverse samples and experimental conditions.Intuitive Controls: The user-friendly interface simplifies pump operation, allowing for easy programming and monitoring. Spend less time on instrument setup and more time focusing on your research.Applications: Whether you’re in pharmaceuticals, biotechnology, environmental analysis, or academic research, our HPLC pump is the go-to solution for achieving unparalleled precision in liquid chromatography.Conclusion: Elevate your chromatography experiments with our HPLC pump—where precision meets reliability. Experience the future of liquid chromatography and unlock new possibilities in your laboratory. Contact us today to discover how our HPLC pump can transform your research endeavors.<h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0,01 ml/min – 9,99 ml/min with step 0.01 ml/min (analytical)</li><li>Pressure: 35 Mpa/5000 psi (analytical, PEEK)</li><li>Flow precision: ± 0,2% RSD @ 1mL/min. and 7 MPa psi&nbsp;</li><li>Flow accuracy: ± 1% @ 1mL/min. and 7 MPa psi (analytical)</li><li>Pressure accuracy: ± 2% of full-scale, with 80:20 H2O/IPA @ 7 MPa</li><li>Pulsation: better than ± 0.5% @ 1mL/min. and 7 MPa&nbsp;</li><li>Remote control: USB</li><li>Remote control: Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/isocratic-pumps/p102-hplc-pump-dual-head-peek-biocompatible/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex Streamline™ Binary High Pressure Gradient system, Stainless Steel

Binary high pressure gradient Streamline system in stainless steel version, consisting of two P1m+P1s pumps with programmable mixing of two mobile phase components at high pressure with 0.1% accuracy.

Binary high pressure gradient Streamline system in stainless steel version, consisting of two P1m+P1s pumps with programmable mixing of two mobile phase components at high pressure with 0.1% accuracy.<blockquote>Price 9 333 € ex VAT</blockquote>An integrated two-channel degasser is a recommended part locvated on the top in the solvent cabinet. In the analytical version, the flow rate range from 0.001 ml/min to 10 ml/min is adjustable to 0.001 ml/min accuracy with a maximum working pressure of 42 MPa (6,000 psi). Flow rate adjustment accuracy is ±1% and flow rate variation is better than ±0.1%. A unique feature is an active piston and seal rinse that prevents crystallization of buffers.A touch screen display on the front panel allows intuitive control of the pump. The display shows the flow rate. A PRIME function is also directly available for flushing at increased flow rates. A cabinet is included for placing bottles with mobile phases. Control and programming of the gradient is done from the Clarity data station.<figure class="image"><img style="aspect-ratio:800/600;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Streamline_P1q_HPLC_Pump_PEEK_c4ca5fdaa4.jpg" alt="Watrex: Streamline™ Binary High Pressure Gradient system, Stainless Steel" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_Streamline_P1q_HPLC_Pump_PEEK_c4ca5fdaa4.jpg 208w," sizes="100vw" width="800" height="600"></figure><h3>PUMP FEATURES</h3><ul><li>Each pump has a single stepper motor driven, dual head positive displacement pump (pump heads 180° out of phase)</li><li>316 Stainless Steel pump heads and fluid path</li><li>Incorporates a diaphragm-type pulse damper, which reduces pulsation in the system by as much as 90% and includes an isolated pressure transducer (i.e., the transducer adds no dead volume).</li><li>Ruby/Sapphire Check Valves (1/16” ball)</li><li>Front panel flow adjustment in 0.001 mL/min increments</li><li>Upper and Lower Pressure Limits: Automatically turns the pump OFF if the system pressure exceeds the maximum pressure limit, or drops below minimum pressure limit</li><li>Microprocessor advanced control with advanced pre-compression algorithm and user calibration feature</li><li>Back panel USB communications port for complete control and status monitoring; Clarity Driver available</li><li>Automatic piston wash (self-flush)</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0.001 ml/min – 10 ml/min with step 0.001 ml/min</li><li>Pressure: 42 MPa/6000 psi</li><li>Pulsation: ± 1% @ from 7 MPa to 42 MPa</li><li>Pressure Accuracy: ± 2% of full-scale, with IPA</li><li>Flow Accuracy:&nbsp;better than ± 1% @ 10mL/min</li><li>Flow Precision: better then 0.1% RSD or 0.2 min SD, whichever is greater, across the full flow range, 20 MPa, with degassed methanol</li><li>Remote control: USB</li><li>I/O connector:&nbsp;Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/gradient-pumps/streamline-binary-high-pressure-gradient-system-stainless-steel/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

Watrex Streamline™ Binary High Pressure Gradient system, PEEK

Binary high pressure gradient Streamline system in PEEK version, consisting of two P1m+P1s pumps with programmable mixing of two mobile phase components at high pressure with 0.1% accuracy.

Binary high pressure gradient Streamline system in PEEK version, consisting of two P1m+P1s pumps with programmable mixing of two mobile phase components at high pressure with 0.1% accuracy (between 10% and 90% mixing ratios).<blockquote>Price 9 333 € ex VAT</blockquote>An integrated two-channel degasser is a recommended part locvated on the top in the solvent cabinet. In the analytical version, the flow rate range from 0.001 ml/min to 10 ml/min is adjustable to 0.001 ml/min accuracy with a maximum working pressure of 35 MPa (5,000 psi). Flow rate adjustment accuracy is ±1% and flow rate variation is better than ±0.1%. A unique feature is an active piston and seal rinse that prevents crystallization of buffers.A touch screen display on the front panel allows intuitive control of the pump. The display shows the flow rate. A PRIME function is also directly available for flushing at increased flow rates. A cabinet is included for placing bottles with mobile phases. Control and programming of the gradient is done from the Clarity data station.<figure class="image"><img style="aspect-ratio:800/600;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Watrex_Streamline_P1q_HPLC_Pump_PEEK_c4ca5fdaa4.jpg" alt="Watrex: Streamline™ Binary High Pressure Gradient system, PEEK" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Watrex_Streamline_P1q_HPLC_Pump_PEEK_c4ca5fdaa4.jpg 208w," sizes="100vw" width="800" height="600"></figure><h3>PUMP FEATURES</h3><ul><li>Each pump has a single stepper motor driven, dual head positive displacement pump (pump heads 180° out of phase)</li><li>PEEK pump heads and fluid path</li><li>Incorporates a diaphragm-type pulse damper, which reduces pulsation in the system by as much as 90% and includes an isolated pressure transducer (i.e., the transducer adds no dead volume).</li><li>Ruby/Sapphire Check Valves (1/16” ball)</li><li>Front panel flow adjustment in 0.001 mL/min increments</li><li>Upper and Lower Pressure Limits: Automatically turns the pump OFF if the system pressure exceeds the maximum pressure limit, or drops below minimum pressure limit</li><li>Microprocessor advanced control with advanced pre-compression algorithm and user calibration feature</li><li>Back panel USB communications port for complete control and status monitoring; Clarity Driver available</li><li>Automatic piston wash (self-flush)</li></ul><h3>TECHNICAL SPECIFICATION</h3><ul><li>Flow Rates: 0.001 ml/min – 10 ml/min with step 0.001 ml/min</li><li>Pressure: 35 MPa/5000 psi</li><li>Pulsation: ± 1% @ from 7 MPa to 42 MPa</li><li>Pressure Accuracy: ± 2% of full-scale, with IPA</li><li>Flow Accuracy:&nbsp;better than ± 1% @ 10mL/min</li><li>Flow Precision: better then 0.1% RSD or 0.2 min SD, whichever is greater, across the full flow range, 20 MPa, with degassed methanol</li><li>Remote control: USB</li><li>I/O connector:&nbsp;Start, Stop, Status, Error</li></ul>You can also visit this product on the <a target="_blank" rel="noopener noreferrer" href="https://watrex.com/obchod/chromatography/pumps/gradient-pumps/streamline-binary-high-pressure-gradient-system-peek/?utm_source=labrulez&amp;utm_medium=propagace&amp;utm_campaign=labrulez_produkty">Watrex website</a>.

KNAUER High Precision AZURA P 6.1L HPLC Pump

KNAUER AZURA P 6.1L HPLC pump with up to 1000 bar, precise gradient control, and low pulsation for reliable UHPLC workflows.

The KNAUER AZURA P 6.1L is a high-precision analytical HPLC pump designed for accurate and reproducible solvent delivery in both HPLC and UHPLC applications.The pump combines essential features of a modern pumping system, including low pulsation, high pressure capability, precise gradient formation, and flexible configuration. It is available in both HPG (high-pressure gradient) and LPG (low-pressure gradient) versions, with a flow range up to 50 mL/min.The system uses a dual serial piston mechanism with active pulsation compensation, ensuring excellent flow stability under all conditions. A low-dead-volume microfluidic mixer enables efficient and precise solvent mixing.Different pump heads are available:<ul><li>up to 10 mL/min at 862 bar</li><li>up to 5 mL/min at 1000 bar</li></ul>Optional configurations include biocompatible materials (PEEK, ceramic, titanium) and specialized setups for normal phase applications (e.g., hexane, heptane).<h4>Key Features</h4><ul><li>High-precision analytical HPLC/UHPLC pump</li><li>Pressure up to 1000 bar</li><li>Flow rates up to 50 mL/min</li><li>Dual piston system with low pulsation</li><li>Active pulsation compensation</li><li>HPG and LPG gradient configurations</li><li>Microfluidic mixer (50–600 µl)</li><li>RFID pump head detection</li><li>Optional degasser</li><li>Biocompatible configurations available</li><li>Robust operation with demanding solvents</li></ul><h3>Technical Specifications</h3><h4>Solvent Delivery</h4><ul><li>Pump type: analytical HPLC pump</li><li>Mechanism: dual serial piston</li><li>Flow range: 0.001 – 50 mL/min</li><li>Max pressure: up to 1000 bar</li><li>Flow accuracy: ± 0.25%</li><li>Precision: ≤ 0.04% RSD</li></ul><h4>Gradient</h4><ul><li>Range: 0–100% (0.1% steps)</li><li>HPG accuracy: ± 0.3%</li><li>HPG precision: &lt; 0.1% RSD</li><li>LPG accuracy: ± 0.3% to ± 2%</li><li>LPG precision: &lt; 0.5% RSD</li></ul><h4>Mixing</h4><ul><li>Microfluidic mixer</li><li>Volumes: 50 / 100 / 200 / 400 / 600 µl</li><li>Low dead volume</li></ul><h4>Degasser (optional)</h4><ul><li>2–4 channels</li><li>Max flow: 10 mL/min per channel</li><li>Residual O₂: &lt; 0.5 ppm</li><li>Membrane: fluoropolymer</li></ul><h4>Materials</h4><ul><li>PEEK, Tefzel®, Systec AF</li><li>Optional biocompatible materials (titanium, ceramic)</li></ul><h4>Control &amp; Communication</h4><ul><li>LAN, analog inputs</li><li>Event outputs (TTL, relay)</li><li>Optional mobile control</li><li>RFID pump head detection</li></ul><h4>Operating Conditions</h4><ul><li>Temperature: 4–40 °C</li><li>Humidity: &lt; 90% non-condensing</li></ul><h4>Dimensions &amp; Power</h4><ul><li>Dimensions: 361 × 208 × 523 mm</li><li>Weight: 14.1 kg</li><li>Power supply: 100–240 V, 50–60 Hz</li><li>Power consumption: max 100 W</li></ul>

KNAUER High Precision AZURA P 8.1L UHPLC Pump

KNAUER AZURA P 8.1L UHPLC pump with up to 1240 bar, adaptive pulsation compensation, and high precision for demanding UHPLC applications.

The KNAUER AZURA P 8.1L is a high-performance UHPLC pump designed for ultra-fast and high-resolution chromatographic applications. With a maximum pressure of 1240 bar (124 MPa) and flow rates up to 5 mL/min, it meets the demands of modern UHPLC workflows.The pump features a dual serial piston mechanism combined with adaptive pulsation compensation, which operates independently of flow rate, pressure, and solvent type through real-time monitoring of eluent compressibility and variable piston stroke.Together with KNAUER’s advanced piston drive technology, this results in exceptional flow reproducibility under all operating conditions. High-precision in-house manufacturing ensures long piston seal lifetime and maximum system uptime.<h4>Key Features</h4><ul><li>UHPLC pump up to 1240 bar</li><li>Flow rates up to 5 mL/min</li><li>Dual serial piston system</li><li>Adaptive pulsation compensation</li><li>Excellent flow reproducibility</li><li>HPG gradient capability</li><li>Integrated 4-channel degasser</li><li>RFID pump head detection</li><li>Low baseline noise</li><li>High durability and long lifetime</li><li>Compatible with UHPLC and LC-MS systems</li></ul><h3>Technical Specifications</h3><h4>Solvent Delivery</h4><ul><li>Pump type: analytical UHPLC pump</li><li>Mechanism: dual serial piston</li><li>Max pressure: 1240 bar</li><li>Flow rate: up to 5 mL/min</li><li>Flow accuracy: ± 0.25%</li><li>Precision: ≤ 0.04% RSD</li></ul><h4>Gradient</h4><ul><li>Type: HPG (high-pressure gradient)</li><li>Range: 0–100% (0.1% steps)</li><li>Accuracy: ± 0.3%</li><li>Precision: &lt; 0.1% RSD</li></ul><h4>Degasser</h4><ul><li>Channels: 4</li><li>Max flow: 5 mL/min per channel</li><li>Residual O₂: &lt; 0.5 ppm</li><li>Technology: fluoropolymer membrane</li></ul><h4>Connections</h4><ul><li>Inlet: UNF 1/4-28 (1/8” tubing)</li><li>Outlet: UNF 10-32 (1/16” capillary)</li></ul><h4>Materials</h4><ul><li>PEEK, Tefzel®, Systec AF</li><li>Compatible with most solvents (except HCl and halogenated hydrocarbons)</li></ul><h4>Control &amp; Communication</h4><ul><li>LAN, analog inputs</li><li>Event outputs (TTL, relay)</li><li>Optional mobile control</li><li>RFID pump head detection</li></ul><h4>Safety &amp; Operating Conditions</h4><ul><li>Leak sensor</li><li>Soft start and programmable pressure limits</li><li>Temperature: 4–40 °C</li><li>Humidity: &lt; 90% non-condensing</li></ul><h4>Dimensions &amp; Power</h4><ul><li>Dimensions: 361 × 208 × 523 mm</li><li>Weight: 26.7 kg</li><li>Power supply: 100–240 V, 50–60 Hz</li><li>Power consumption: max 310 W</li></ul>

Products from category HPLC pumps - page 1

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