<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 31st August 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you application notes by <strong>Agilent Technologies</strong>, <strong>Shimadzu, Thermo Fisher Scientific </strong>and presentation by<strong> MDCW / Liège University!</strong></p><h3><strong>1. Agilent Technologies: Extend the time window for the detection of low level anabolic‑androgenic steroids and their metabolites</strong></h3><p><strong>Steroid profiling, screening, and confirmatory analysis using the </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=10&amp;search=7010"><strong>Agilent&nbsp;7010 GC/MS mass spectrometer</strong></a></p><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/5991_9045_EN_Doping_Control_App_Note_1_13dde5f053.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>Doping laboratories want to have lower detection limits to be able to identify and quantitate illegal drugs for a longer time window between doping and urine sample collection. This Application Note describes how the doping control lab in Kreischa, Germany used the Agilent 7010 Triple Quadrupole GC/MS System (TQ) for enhanced targeted detection of anabolic‑androgenic steroids in urine samples. The 7010 TQ enabled higher sensitivity, longer maintenance-free intervals, and more stable operation than earlier models, and satisfied all measurement specifications required by the World Anti‑Doping Agency (WADA). The 7010 TQ GC/MS ion source produces more ions, and provides exceptional sensitivity for the detection of low intensity metabolites weeks after drug ingestion. However, this higher sensitivity may lead to saturation of endogenous components naturally present at higher concentrations. This method provides a sensitive and robust operation over a wide concentration range, permitting the detection of low-concentration exogenous species in the presence of high‑concentration endogenous species, which can vary with ethnicity.</p><h4><strong>Experimental</strong></h4><p>The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=10&amp;search=7010"><strong>Agilent 7010 GC/TQ system</strong></a> consists of an <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=10&amp;search=7890"><strong>Agilent 7890 GC</strong></a> with multimode inlet and backflush, an<strong> Agilent 7993A</strong>, and the Agilent 7010 TQ mass spectrometer.</p><h4><strong>Conclusions&nbsp;</strong></h4><p>Based on the method optimization and thorough testing at the Kreischa lab, an Agilent 7010 GC/MS-based protocol was developed. This protocol fulfills the screening and confirmation requirements of steroid measurements in doping control labs. With this method, it is possible to detect traces of exogenous anabolic steroid metabolites while quantifying small concentrations of testosterone and epitestosterone typical in Asian populations. It permits the measurement of high‑abundance endogenous steroids such as androsterone and etiocholanolone in the same injection, while analyzing testosterone/epitestosterone and androsterone/etiocholanolone ratios without suppression.&nbsp;</p><p>The backflush capability of the system protects the analytical column, and consequently the mass spectrometer, by removing heavy matrix components. This allowed more than 6,000 samples to be analyzed on the same column without requiring ion source cleaning or filament change. It also demonstrated that the higher, 130&nbsp;eV electron energy did not sacrifice the filament lifetime. It performed reliable measurements of both trace (0.2&nbsp;pg on‑column) and high (10,000&nbsp;pg on‑column) concentration analytes in the same run.&nbsp;</p><p>The method validation revealed that the exceptional sensitivity offered by the 7010 GC/MS can be used to:&nbsp;</p><ul><li>Improve the trace detection ability of the method&nbsp;</li><li>Reduce the amount of sample&nbsp;injected&nbsp;</li><li>Extend maintenance-free intervals</li></ul><h3><strong>2. MDCW / Liège University: The Century Mix: updates and cool projects</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/DG_1_Dimandja_Stefanuto_34c4a66c3d.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>The presentation <strong>“The Century Mix: updates and cool projects”</strong> introduces the Century Mix, a standardized reference mixture developed for comprehensive two-dimensional gas chromatography (GC×GC). The mixture contains <strong>100 compounds representing a broad range of chemical classes</strong>, including alkanes, alcohols, ketones, esters, lactones, phthalates, and aromatic compounds. Stability was a key criterion in compound selection, and the mixture was developed through cross-laboratory collaboration for <strong>column characterization, method assessment, and quality control</strong>. Its structured chromatographic behavior also makes it useful for studying how different compound classes behave in GC×GC separations.</p><p>A major part of the work examined the <strong>factors influencing retention indices (RI) in GC×GC systems</strong>, which are important for reliable compound annotation in non-targeted analysis. An inter-laboratory study involved <strong>11 GC×GC systems</strong> using cryogenic, Peltier, and flow modulation, different detectors, and both normal and reversed column configurations. Principal component analysis showed clear grouping according to normal versus reversed orthogonality, confirming the strong influence of stationary-phase configuration. A subsequent design-of-experiments study evaluated <strong>140 combinations</strong> of temperature ramp rate, carrier-gas flow rate, modulation period, and secondary-oven temperature offset.</p><p>The results showed that the influence of experimental conditions is strongly <strong>compound dependent</strong>. Of the compounds evaluated in the statistical model, 33 showed RI variation that could be linked to the investigated parameters, whereas 43 did not follow the model well. Compounds such as quinoline, phthalates, lactones, terpenes, and some aromatic compounds showed particularly pronounced effects. For quinoline, for example, the model explained about <strong>93% of RI variability</strong>, with differences of approximately 75 RI units across the tested conditions, while 2-hexanone showed considerably weaker dependence. Overall, <strong>temperature ramp rate and flow rate emerged as particularly important parameters</strong>, although the magnitude of their effect depended on compound chemistry and column configuration.</p><p>The Century Mix is therefore being developed not only as a characterization mixture but also as a tool for <strong>system quality control and more reliable retention-index prediction</strong>. Repeated standardized QC measurements demonstrated very low RI variability and can be used to monitor system stability, experimental effects, and potential instrument drift. The broader goal is to better understand the fundamental chemistry governing GC×GC retention and ultimately improve method development, data processing, and identification of unknown compounds by combining high-quality separations, mass spectra, and predicted retention information.</p><h3><strong>3. Shimadzu: Determination of Free and Total Glycerol and Mono-, Di-, and Triglyceride Contents in Biodiesel According to EN 14105</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_05_sca_180_055_en_9b8677ed6a.pdf"><strong>Full PDF for download</strong></a></li></ul><h4><strong>User benefits</strong></h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=1&amp;search=2060"><strong>Nexis GC-2060</strong></a> offers reliable analysis of biodiesel samples regarding their free and total glycerol and mono-, di-, and triglyceride contents, using hydrogen as a cost-effective carrier gas&nbsp;</li><li>Hydrogen carrier gas can be used safely through built-in safety measures</li><li>The multi-mode injection unit (MMI) allows selection of the preferred injection mode – direct (simple OCI) or convenient splitless PTV mode – both delivering excellent instrument performance in line with the standard’s requirements</li></ul><p>Playing a vital part in countries’ efforts to lower greenhouse gas emissions, biofuels can be manufactured from various feedstocks such as vegetable oils, animal-derived fats, and recycled cooking oils. Biodiesel production predominantly uses rapeseed, soybean, and palm oils. Because feedstocks are so varied, ongoing quality monitoring is essential - since the raw material’s quality greatly influencesthe final biodiesel quality.&nbsp;</p><p>The EN 14105:2024 describes the determination of free and total glycerol contents and mono-, di-, and triglyceride contents in biodiesel by means of gas chromatography with flame ionization detection (GC-FID). Injection shall be performed via on-column injector or an equivalent device<sup>1</sup>.&nbsp;</p><p>This study shows the analysis of biodiesel originating from rapeseed, soybean, and palm oil using the Nexis GC-2060 gas chromatograph and its multi-mode injection unit (MMI).</p><h4><strong>Configuration and Analysis Conditions</strong></h4><p>Gas chromatograph <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=1&amp;search=2060"><strong>Nexis GC-2060</strong></a> with multi-mode injection unit (MMI), flame-ionization detector (FID) and autosampler <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/gcms/library?mainauthorItems=1&amp;search=AOC+-30i"><strong>AOC -30i</strong></a>.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>Nexis and AOC are trademarks of Shimadzu Corporation or its affiliated companies in Japan and/or other countries.. Nexis GC-2060 provides reliable analysis of biodiesel samples for glycerol and glyceride contents according to EN 14105:2024 across the commonly used feedstocks. It supports hydrogen as a cost-effective carrier gas, while the multi-mode injection unit (MMI) offers selection of the injection mode based on user preference: direct mode representing simple on-column (OCI) analysis or splitless programmed temperature vaporization (PTV) mode as a convenient alternative that delivers comparable performance.</p><h3><strong>4. Thermo Fisher Scientific: Streamlined static headspace GC–MS approach for detection of impurities in recycled PET</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_004458_gc_ms_impurities_recycled_pet_an004458_na_en_6cb2435671.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Polyethylene terephthalate (PET) is a widely used thermoplastic polymer valued for its strength, low weight, durability, and adaptability. Owing to these properties, it is extensively applied in packaging, textile fibers, and electronic components. PET is particularly suitable for recycling because it can be melted and reshaped multiple times with minimal loss of performance, and it is easily recognizable by the recycling code “1” (♳). The recycling of PET involves several stages, including collection, sorting, transport, processing, washing, pelletizing, and remanufacturing into new products [1]. However, during these steps, contaminants such as plasticizers, residual monomers, and degradation byproducts may be introduced.&nbsp;</p><p>The presence of such substances can pose potential risks to both environmental and human health, making the identification and characterization of contaminants in recycled PET essential for evaluating material quality and safety. Among the non-intentionally added substances (NIAS), benzene, acetaldehyde, and limonene are of particular relevance. Benzene is a recognized carcinogen and represents a serious health concern if present in PET. It may form as a degradation product of PET, with the reaction catalyzed by acidic compounds released at high temperatures by polymer impurities such as polyvinyl chloride (PVC). Poor temperature control or overheating can increase benzene formation as a degradation byproduct. Acetaldehyde, another degradation product of PET generated during bottle manufacturing, can alter the sensory properties of bottled beverages. Limonene, a flavor compound commonly present in soft drinks, may be absorbed into recycled PET and subsequently migrate into packaged beverages, potentially affecting product quality.&nbsp;</p><p>Gas chromatography coupled to headspace sampling is a fast and simple technique that enables the extraction of volatile and semivolatile compounds from solid and liquid samples without the need for time-consuming sample preparation.&nbsp;</p><p>In this study, headspace sampling coupled to single quadrupole mass spectrometry was used to assess the overall quantitative performance for analysis of acetaldehyde, benzene, and limonene in recycled PET packaging.&nbsp;</p><p>The capability of the Thermo Scientific™ ISQ™ 7610 single quadrupole GC–MS of combining the simultaneous acquisition of both single ion monitoring (SIM) and full scan (FS) allowed for sensitive targeted analysis as well as screening of unknown contaminants possibly present in recycled PET bottles.</p><h4><strong>Experimental&nbsp;</strong></h4><p>In all experiments, a <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/64"><strong>TriPlus 500 HS autosampler</strong></a> was coupled to a <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/486"><strong>Thermo Scientific™ TRACE™ 1610 Gas Chromatograph (GC)</strong></a>, configured with a Thermo Scientific™ iConnect™ Split/splitless Injector Module (iConnect-SSL), and connected to an <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/484"><strong>ISQ 7610 single quadrupole mass spectrometer</strong></a>.&nbsp;</p><p>The separation of the target analytes was achieved using a <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1751"><strong>Thermo Scientific™ Trace GOLD™ TG-624 SILMS capillary column</strong></a>, 60 m x 0.25 mm x 1.4 µm (Part No. 26059-3330). This column provides a low to mid polarity phase with high thermal stability (maximum operating temperatures up to 320 °C) and high inertness, enabling Gaussian peak shapes for analysis of volatile organics. The TriPlus 500 HS autosampler is connected directly to the analytical column, removing the use of a long external transfer line. In this configuration, the SSL injector module is used only for the pneumatic control of the carrier gas and split flow.</p><h4><strong>Conclusions&nbsp;</strong></h4><p>The results presented in this work demonstrate that headspace coupled to GC–MS provides a suitable and simple solution for analysis of contaminants in rPET, with no complex sample preparation required.&nbsp;</p><ul><li>The capability of combining FS with SIM acquisition allows for qualitative and quantitative analysis, increasing confidence in compound identification through spectral comparison with NIST library and allowing for the detection of possible analyte co-elution.&nbsp;</li><li>The TriPlus 500 HS autosampler provides highly repeatable solventless extraction from solid samples with absolute area counts RSD &lt; 5%, permitting reliable and consistent quantitative data.&nbsp;</li><li>The ISQ 7610 single quadrupole GC–MS demonstrates an extended linear response (≥ 4–5 orders of magnitude) with R2 ≥ 0.997, calculated amounts within ± 20% the expected value, and ion ratio deviation ≤ 15% across the calibration curve.&nbsp;</li><li>Sensitivity was demonstrated with overall calculated LOD ≤ 0.03 ng/µL.</li><li>Chromeleon CDS helps ensure data integrity, traceability, and effective data management from instrument control to the final report streamlining analysis and data review processes.</li></ul></div></div></div></div></div></div></section></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 36, 2026

News from LabRulezLCMS Library - Week 36, 2026

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 31st August 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring you brochures by <strong>Agilent Technologies </strong>and<strong> Waters Corporation </strong>and application notes by <strong>Shimadzu </strong>and<strong> Thermo Fisher Scientific!</strong></p><h3><strong>1. Agilent Technologies: Agilent OpenLab ICP-MS Software</strong></h3><p><strong>Simplify every step of ICP-MS analysis</strong></p><p><strong>For Agilent </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=7800"><strong>7800</strong></a><strong>, </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=7850"><strong>7850</strong></a><strong>, and </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=7900"><strong>7900</strong></a><strong> ICP-MS systems, and Agilent </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=8900"><strong>8900</strong></a><strong> and </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=9500"><strong>9500 ICP-QQQ</strong></a><strong> systems.</strong></p><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/br_openlab_icp_ms_software_5994_9288en_agilent_05f01dcdef.pdf"><strong>Full PDF for download</strong></a><strong>&nbsp;</strong></li></ul><p>The brochure introduces <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=OpenLab+ICP-MS+Software"><strong>Agilent OpenLab ICP-MS Software</strong></a>, designed to simplify routine operation and data handling for <strong>Agilent 7800, 7850, and 7900 ICP-MS systems</strong> and the <strong>8900</strong> and <strong>9500</strong> <strong>ICP-QQQ systems</strong>. The software supports the complete analytical workflow—from checking instrument readiness and creating batches to acquisition, data review, reporting, and compliance. A central dashboard provides an overview of system status, maintenance requirements, instrument health, and utilization, while Smart EMF and post-run performance checks help users identify when maintenance may be required. Guided Diagnostics, Meter Monitor, and time-stamped system records also support troubleshooting by tracking parameters such as vacuum levels, gas flows, and temperatures.</p><p>Method and batch setup are designed to reduce manual configuration. Batches can be created from preset methods, templates, existing batches, Method Wizard, or Method Advisor, and legacy Agilent ICP-MS MassHunter batches can be opened directly in OpenLab ICP-MS. For the <strong>9500 ICP-QQQ</strong>, Method Advisor provides an element-focused approach in which users select target elements and calibration information while the software applies recommended acquisition masses and cell-gas conditions. Preset methods are available for applications including <strong>EPA 200.8/EPA 6020, USP &lt;232&gt;, ICH Q3D, and Chinese Pharmacopoeia requirements</strong>, while an IntelliQuant Screening preset supports semiquantitative screening of unknown samples. Routine instrument tasks can also be automated through autotuning, startup checks, batch queues, end-of-run verification, rinse functions, and automatic shutdown.</p><p>For data evaluation, OpenLab ICP-MS provides a real-time workspace where users can review analyte concentrations, internal-standard recoveries, stability plots, spectra or chromatograms, calibration information, QC charts, and IntelliQuant results in a single view. <strong>IntelliQuant</strong> acquires a complete mass spectrum and displays semiquantitative elemental concentrations using a color-coded periodic table, while <strong>IntelliQuant Star Rating</strong> assigns a zero-to-five-star data-quality score based on factors such as potential interferences, calibration quality, background, detection limits, and precision. Reporting options include whole-batch reports, elemental impurity reports for USP &lt;232&gt;/&lt;233&gt; and ICH Q3D, customizable reports, structured CSV export, and direct data transfer to LIMS.</p><p>The software can be expanded for specialized applications, including <strong>LC-ICP-MS and GC-ICP-MS</strong>, advanced QC workflows, single-particle ICP-MS and FFF-ICP-MS, ADS 2 automation, semiconductor analysis, and peripheral-device control. Supported analytical approaches include external calibration, standard additions, semiquantitative calibration, isotope ratios, and isotope dilution. For regulated laboratories, OpenLab ICP-MS can be combined with scalable OpenLab compliance solutions providing electronic signatures, user access control, configurable roles, system activity logs, and audit trails, supporting workflows subject to <strong>21 CFR Part 11, EU Annex 11, and equivalent regulations</strong>. Overall, the platform is positioned as a unified environment for routine and advanced ICP-MS workflows, combining instrument control, method setup, diagnostics, data-quality assessment, reporting, and compliance support.</p><h3><strong>2. Shimadzu: Identification of Virgin PET and Recycled PET by X-ray Fluorescence Spectrometry</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_01_01204_en_f3f20ff020.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User benefits</strong></h5><ul><li>EDX enables the identification of recycled PET.&nbsp;</li><li>Measurements are quick and simple, require no cumbersome pretreatment, and can be automated using a multi-sample turret.&nbsp;</li><li>The instrument offers excellent cost-performance and supports the detection of a wide range of elements.</li></ul><p>Establishing a sustainable circular economy is a major societal challenge, and recycling plastic materials such as PET (polyethylene terephthalate) plays a particularly important role in reducing environmental impact. Large numbers of PET bottles and molded products are used every day in the food and beverage sectors. To recycle these materials safely and reliably, technologies are required that can accurately identify their origin. In practice, however, appearance and conventional physical properties alone are insufficient to distinguish virgin material from recycled material, creating a need for a more reliable identification method.&nbsp;</p><p>For rapid identification in industrial settings, a method requiring little or no pretreatment is highly desirable. In some cases, nondestructive analysis is also needed to enable subsequent application of other analytical techniques. This article presents a practical approach in which metal catalysts present in PET are detected by EDX (Energy-Dispersive X-ray Spectroscopy) and used to distinguish material-recycled PET from virgin PET.</p><h4><strong>Principle and Overview&nbsp;</strong></h4><p>Metal catalysts such as antimony (Sb) and germanium (Ge) are used in the synthesis of PET resin. These catalyst metals have been reported to be useful indicators of material origin. 1),2) For example, Sb and Ge are frequently detected together in material-recycled PET, whereas only one catalyst metal is detected in chemically recycled PET and virgin PET. This likely reflects the fact that material-recycled PET is derived from a mixture of feedstocks using different catalysts.&nbsp;</p><p>ICP-AES (ICP optical emission spectrometry) and ICP-MS (ICP mass spectrometry), which are commonly applied to catalyst metal analysis, provide high sensitivity and accuracy. However, they require pretreatment to convert the sample into a solution, thereby lengthening the analytical workflow. By contrast, EDX can measure solid samples directly, making it well-suited to applications requiring rapid results, such as incoming material inspection and in-line analysis in molding plants. Because EDX is non-destructive, it is also suitable for multimodal analytical workflows.&nbsp;</p><p>On the other hand, some commercially available handheld EDX instruments do not support elements such as Sb and Ge. At the same time, higher-end systems may not offer the specifications or price range needed for industrial deployment. The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=1&amp;search=EDX-7200"><strong>EDX-7200</strong></a> supports a broad range of elements with excellent cost performance. This article describes the analysis of Sb and Ge in PET using this instrument.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>EDX enables rapid and straightforward elemental analysis without cumbersome sample pretreatment. Previous studies have shown that the presence of Sb and Ge can be used to identify recycled PET. Building on this concept, this article presents a practical analytical approach based on EDX. Using the EDX-7200, which combines broad elemental coverage with excellent cost performance, the proposed method provides a practical tool for rapid on-site identification, quality control, and traceability management. When combined with physical property data and other information, this approach is expected to contribute to the safety assessment and quality assurance of recycled materials, thereby supporting a more advanced circular economy.</p><h3><strong>3. Thermo Fisher Scientific: Optimizing lithium-ion battery recycling operations using handheld XRF analysis</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/lithium_ion_battery_recycling_handheld_xrf_analysis_an1120_en_4c00477b78.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The shift to a low-carbon economy and the adoption of electric vehicles will drive an exponential increase in the demand for lithium-ion batteries. As a corollary to this, the International Energy Agency expects the demand for some key commodities to increase significantly over the next two decades: the demand for Copper (Cu) is anticipated to increase by more than 40%; for nickel (Ni) and cobalt (Co), by 60-70% each; and for lithium (Li), by nearly 90%.¹ This will translate into increased mining activities and potentially generate larger amounts of deleterious waste.&nbsp;</p><p>To reduce the environmental impact and limit reliance on scarce commodities associated with economical and geopolitical implications, several countries have implemented regulations regarding producers’ responsibilities.² These regulations contain both incentives and accountability guidelines for lithium-ion battery and electric vehicles manufacturers. Their goal is to facilitate the emergence of a circular economy in which recycling will increasingly contribute to the supply of the strategic raw materials.&nbsp;</p><p>Lithium-ion batteries are made of multiple components, the most valuable being the cathode that contains between 40 and 70% ³, ⁴ of the total value of the battery, depending on its exact chemistry. As of 2023, lithium nickel cobalt manganese oxides (NCM) account for 66% of lithium-ion battery cathode active materials for electric vehicles, followed by lithium iron phosphates (LFP) which account for 24%, and lithium nickel cobalt aluminum oxide (NCA) accounts for the remaining 10%.³</p><h4><strong>Handheld X-ray Fluorescence Analysis&nbsp;</strong></h4><p>Handheld X-ray fluorescence analysis (HHXRF) is an elemental analysis technique that has proven to be cost-effective in recycling areas such as scrap metal and automotive catalytic converters. HHXRF can measure elements from magnesium (Mg) to uranium (U) in various types of materials such as metals and alloys; non-metallic inorganic materials such as ceramics; or ores or plastics. The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1993"><strong>Thermo Scientific™ Niton™ XL2</strong></a> and <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1992"><strong>Thermo Scientific™ Niton™ XL5 Plus Handheld XRF Analyzers </strong></a>deliver accurate elemental analysis in real time, with little or no sample preparation, across multiple steps of the lithium-ion battery recycling workflow. Although handheld XRF does not detect lithium, it can measure most elements from the periodic table including nickel or cobalt which often command much higher value than the lithium in a lithium-ion battery.⁴</p><h4><strong>Conclusion&nbsp;</strong></h4><p>There is no ideal process to recycle lithium-ion batteries that simultaneously incorporates low environmental impact, high metal recovery yield, and economic viability. Because of the variety of technologies and materials used, recycling lithium-ion batteries is a complex journey with multiple possible paths. HHXRF helps recyclers by generating lab-quality data in real time, allowing them to optimize their processes and make fast decisions that generate significant benefits:&nbsp;</p><ul><li>Unwanted materials containing heavy metals such as lead or cadmium can be prevented from entering subsequent steps in the recycling workflow.&nbsp;</li><li>Materials can be accurately sorted and adequate processes for recovery selected depending on the material type (e.g., LFP vs. MCM).&nbsp;</li><li>The economic value of incoming and outgoing material can be more accurately estimated.</li></ul><h3><strong>4. Waters Corporation: Waters Aura Systems</strong></h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/720009268_7b9ad02cb4.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The presentation introduces the <strong>Waters Aura Systems</strong>, a family of high-throughput, fluidics-free instruments for the characterization and identification of visible and subvisible particles. All Aura platforms provide particle counting, identification, morphology assessment, and flexible sample volumes ranging from microliters to milliliters. The portfolio includes configurations tailored to different applications: <strong>AuraBMI</strong> for biologics particle analysis, <strong>Aura</strong> for particle analysis with identification, <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2437"><strong>AuraPTx</strong></a> for protein formulation development, <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2438"><strong>AuraGT</strong></a> for gene therapy, <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2439"><strong>AuraCL</strong></a> for cell therapy, and <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2190"><strong>Aura+</strong></a> as the most comprehensive platform. The systems are designed for automation-ready operation, straightforward method transfer, and continuity from research through QC.</p><p>A key feature of the Aura platform is the combination of <strong>Backgrounded Membrane Imaging (BMI), Fluorescence Membrane Microscopy (FMM), and Side Illumination Membrane Imaging (SIMI)</strong>. BMI captures particles on a membrane and subtracts the membrane background to improve particle contrast, while FMM uses fluorescent dyes or conjugated antibodies to distinguish specific particle types. This enables differentiation of protein aggregates, cells, viral capsids, degraded excipients, plastics, fibers, and other contaminants that may look similar based on morphology alone. SIMI adds further information for identifying unlabeled inorganic particles such as glass, fibers, and Dynabeads. Together, these techniques provide more specific particle identification than morphology-based classification alone.</p><p>The systems are particularly suited to <strong>biologics, gene therapy, and cell therapy development</strong>. For gene therapy, Aura can evaluate AAV stability, distinguish capsid-related particles, and monitor DNA leakage using SYBR Gold fluorescence, with measurements possible from as little as <strong>5 µL of sample</strong>. For cell therapy, the system can differentiate single cells, cell aggregates, protein aggregates, and extrinsic particles. The platform also supports flexible sample volumes and 24- or 96-well membrane formats, allowing the same general approach to be used from sample-limited early development through larger-volume and QC workflows. The brochure reports excellent quantitative linearity across serial dilutions and emphasizes the ability to preserve sample for additional orthogonal analyses.</p><p>From a technical perspective, Aura Systems provide <strong>100% sampling efficiency</strong>, a particle detection and quantitation range above <strong>1 µm</strong>, and can handle concentrations above <strong>3,000,000 particles/mL</strong> for 1.6 µm particles. Brightfield membrane imaging takes approximately <strong>one minute per sample</strong>, while fluorescence measurements require about <strong>15–30 seconds per sample</strong>. The instruments are compatible with robotic automation and offer different fluorescence-channel configurations depending on the selected Aura model. Overall, the platform is positioned as a comprehensive solution for obtaining quantitative particle counts together with information on particle identity and composition across the development and quality-control lifecycle.</p>

News from LabRulezICPMS Library - Week 36, 2026

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Waters XSelect CSH Phenyl-Hexyl HPLC Columns

Waters XSelect CSH Phenyl-Hexyl with trifunctionally bonded C6 phenyl-ligand is a robust, low bleed sorbent that selectively retains polyaromatic compounds through pi-pi interactions

<p><strong>XSelect CSH Phenyl-Hexyl columns </strong>provide you with<strong> alternative analyte selectivity </strong>compared<strong> to traditional reversed-phase columns </strong>and are a<strong> valuable tool </strong>for <strong>method development. The trifunctionally bonded C6 phenyl-ligand is a robust, low bleed sorbent that selectively retains polyaromatic compounds through pi-pi interactions. </strong>Packed in ultra-low dispersion hardware, 2.5 µm <strong>eXtended Performance</strong> [XP] columns enable exceptional separation performance, robustness and throughput for HPLC assays while enabling a seamless transition path toward UPLC adoption.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_X_Bridge_BEH_C18_HPLC_Column_e96c520ca3.jpg" alt="Waters: XSelect CSH Phenyl-Hexyl HPLC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_X_Bridge_BEH_C18_HPLC_Column_e96c520ca3.jpg 234w," sizes="100vw" width="660" height="440"></p><h4><strong>Specifications</strong></h4><ul><li><strong>Chemistry:</strong> Phenyl</li><li><strong>Separation Mode: </strong>Reversed Phase</li><li><strong>Particle Substrate:</strong> Hybrid</li><li><strong>pH Range Min: </strong>1 pH</li><li><strong>pH Range Max: </strong>11 pH</li><li><strong>Maximum Pressure: </strong>10000 psi (690 Bar)</li><li><strong>Endcapped:</strong> Yes</li><li><strong>Bonding Technology: </strong>Phenyl-Hexyl</li><li><strong>Silanol Activity:</strong> Low</li><li><strong>Particle Shape: </strong>Spherical</li><li><strong>Pore Size: </strong>130 Å</li><li><strong>System: </strong>UHPLC, UPLC</li><li><strong>Particle Technology: </strong>CSH</li><li><strong>USP Classification:</strong> L11</li><li><strong>Carbon Load:</strong> 14 %</li></ul><h4><strong>The Waters XSelect CSH Phenyl-Hexyl HPLC Column is also available as:</strong></h4><h5><strong>Waters XSelect CSH Phenyl-Hexyl HPLC Column with eConnect Column Tag</strong></h5><ul><li>This column comes equipped with an electronic eConnect column tag containing unique column-specific information. These <strong>NFC-enabled device-tagged columns</strong> were developed to automatically identify, track and digitally trace column use history. eConnect columns can be used on <strong>any HPLC</strong>, but its <strong>advantages</strong> are unlocked when used with the <strong>Waters Alliance iS System</strong> running <strong>Empower software</strong>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_X_Bridge_BEH_C18_Column_with_e_Connect_Column_Tag_c056302ec7.jpeg" alt="Waters: XSelect CSH Phenyl-Hexyl HPLC Column with eConnect Column Tag" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_X_Bridge_BEH_C18_Column_with_e_Connect_Column_Tag_c056302ec7.jpeg 234w," sizes="100vw" width="660" height="440"></p><h3><strong>XSelect Columns</strong></h3><h4><strong>Achieve unmatched reproducibility with a wide range of selectivity</strong></h4><p>Quickly and easily develop robust methods compatible with all modern chromatographic detection modes and transfer them from lab to lab with the <strong>XSelect Column family</strong>.</p><p>Designed to help you achieve reproducible and highly selective chromatographic separations, the XSelect Column family features <strong>two base particles technologies</strong>, <strong>Charged Surface Hybrid (CSH)</strong> and <strong>High Strength Silica (HSS)</strong>. With XSelect Columns, method development scientists like you can achieve a wide range of selectivities across all application areas, without compromising performance.</p><h4><strong>Overview</strong></h4><ul><li>Designed for selectivity and stability at low pH</li><li>Superior peak shape for basic compounds</li><li>Highest analyte mass loading available</li><li>Excellent batch-to-batch reproducibility</li><li>Ideal for rapid method development</li><li><strong>CSH Column chemistries: </strong>C18, Fluoro-Phenyl (PFP), and Phenyl-Hexyl, available in 2.5 XP, 3.5, 5 μm analytical and 10 μm OBD preparative sizes</li><li><strong>HSS Column chemistries:</strong> HSS C18, C18 SB, and T3, available in 2.5 XP, 3.5, and 5 μm particle sizes</li><li><strong>Prolonged column lifetimes</strong> with optional <strong>VanGuard Cartridges</strong> specifically designed using XSelect stationary phases</li><li><strong>Recommended Use:</strong> For improving selectivity, peak shape, and retentivity in methods development.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_X_Select_Columns_ff2c4ddb9e/Waters-XSelect-Columns.jpg" alt="Waters: XSelect Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_X_Select_Columns_ff2c4ddb9e/thumbnail_Waters-XSelect-Columns.jpg 242w," sizes="100vw" width="900" height="580"></p>

Waters Nova-Pak Phenyl HPLC Columns

Leverage the phenyl ligand in the Nova-Pak HP Phenyl column to achieve unique compound selectivity with reversed-phase applications.

<p><strong>Nova-Pak HP Phenyl columns are based on 4 µm silica-based particle technology. The phenyl ligand is used to achieve unique compound selectivity with reversed-phase applications.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Atlantis_d_C18_HPLC_Columns_d7a741df9f.jpg" alt="Waters: Nova-Pak Phenyl HPLC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Atlantis_d_C18_HPLC_Columns_d7a741df9f.jpg 234w," sizes="100vw" width="660" height="440"></p><h4><strong>Specifications</strong></h4><ul><li><strong>Chemistry:</strong> Phenyl</li><li><strong>Separation Mode: </strong>Reversed Phase</li><li><strong>Particle Substrate:</strong> Silica</li><li><strong>pH Range Min: </strong>2 pH</li><li><strong>pH Range Max: </strong>8 pH</li><li><strong>Maximum Pressure: </strong>6000 psi (415 Bar)</li><li><strong>Endcapped:</strong> Yes</li><li><strong>Silanol Activity:</strong> Medium</li><li><strong>Particle Shape: </strong>Spherical</li><li><strong>Pore Size: </strong>60 Å</li><li><strong>System: </strong>HPLC</li><li><strong>USP Classification:</strong> L11</li><li><strong>Carbon Load:</strong> 5 %</li></ul><h4><strong>The Waters Nova-Pak Phenyl HPLC Column is also available in these types:</strong></h4><h5><strong>Waters Nova-Pak Phenyl HPLC Column&nbsp;with eConnect Column Tag</strong></h5><ul><li>This column comes equipped with an electronic eConnect column tag containing unique column-specific information. These <strong>NFC-enabled device-tagged columns</strong> were developed to automatically identify, track and digitally trace column use history. eConnect columns can be used on <strong>any HPLC</strong>, but its <strong>advantages</strong> are unlocked when used with the <strong>Waters Alliance iS System</strong> running <strong>Empower software</strong>.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_X_Bridge_BEH_C18_Column_with_e_Connect_Column_Tag_c056302ec7.jpeg" alt="Waters: Nova-Pak Phenyl HPLC Column with eConnect Column Tag" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_X_Bridge_BEH_C18_Column_with_e_Connect_Column_Tag_c056302ec7.jpeg 234w," sizes="100vw" width="660" height="440"></p><h3><strong>Nova-Pak Columns</strong></h3><h4><strong>Scale-up from analytical to prep, simplified</strong></h4><p>Reducing solvent consumption while maintaining resolution for complex mixtures is important, but that’s a challenge with larger particle sizes. With the <strong>smaller particle sizes </strong>and <strong>shorter column lengths</strong> in Nova-Pak Columns, those problems are a thing of the past. The bonded phases of Nova-Pak Columns are available in <strong>4 µm</strong> and <strong>6 µm particle sizes</strong>, offering high resolution and faster, more efficient chromatography over columns packed with larger particle sizes.</p><p><strong>Nova-Pak Analytical Columns</strong> with <strong>4 µm particle size</strong> packing offer a range of <strong>length </strong>options with <strong>75, 100, 150, and 300 mm</strong> length steel columns. The <strong>semi-preparative</strong> <strong>Prep Nova-Pak HR Columns</strong> are packed with<strong> 6 µm particle size</strong> packings for unparalleled separation possibilities. The high-efficiency packing of Prep Nova-Pak HR Columns provides faster separations with less solvent for the added advantage of more concentrated fractions—reducing your preparative chromatography cost. To ensure batch-to-batch reproducibility, all <strong>Nova-Pak C18, C8, Cyano and Phenyl Columns</strong> are packed according to stringent quality control (QC) procedures in Waters <strong>cGMP</strong> manufacturing facility.</p><h4><strong>Overview</strong></h4><ul><li>Reduces solvent consumption while maintaining resolution for complex mixtures</li><li>Packed to stringent QC procedures to ensure batch-to-batch reproducibility</li><li>Chemistries include C18, C8, Cyano, and Phenyl stationary phases</li><li>Available in 4 µm analytical and 6 µm semi-preparative particle sizes</li><li><strong>Recommended Use:</strong> For higher resolution and faster chromatography.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Nova_Pak_Columns_fad066ad02/Waters-Nova-Pak-Columns.jpg" alt="Waters: Nova-Pak Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Nova_Pak_Columns_fad066ad02/thumbnail_Waters-Nova-Pak-Columns.jpg 245w," sizes="100vw" width="900" height="392"></p>

Waters ACQUITY UPLC BEH Phenyl Column

The Waters ACQUITY BEH Phenyl columns provide complementary selectivity to C18 stationary phases, especially for polyaromatic compounds. 

<p><strong>ACQUITY BEH Phenyl </strong>columns provide <strong>complementary selectivity to C18</strong> stationary phases, <strong>especially for polyaromatic compounds</strong>. This sorbent, along with the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1828"><strong>XBridge BEH Phenyl</strong></a>, provide you with the most chemiscally stable phenyl sorbent on the market and provides you with ultra-low column bleed, long column lifetimes and excellent peak shape.</p><h5><strong>Specifications</strong></h5><ul><li><strong>Chemistry:</strong> Phenyl</li><li><strong>Separation Mode: </strong>Reversed Phase</li><li><strong>Particle Substrate:</strong> Hybrid</li><li><strong>pH Range Min</strong>: 1 pH</li><li><strong>pH Range Max: </strong>12 pH</li><li><strong>Maximum Pressure:</strong> 18000 psi (1240 Bar)</li><li><strong>Endcapped: </strong>Yes</li><li><strong>Silanol Activity: </strong>Low</li><li><strong>Particle Shape:</strong> Spherical</li><li><strong>Pore Size: </strong>130 Å</li><li><strong>System: </strong>UHPLC, UPLC</li><li><strong>Particle Technology:</strong> BEH</li><li><strong>USP Classification:</strong> L11</li><li><strong>Carbon Load: </strong>15 %</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_BEH_C8_Column_9c78ca994d.jpg" alt="Waters: ACQUITY UPLC BEH Phenyl Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_BEH_C8_Column_9c78ca994d.jpg 234w," sizes="100vw" width="660" height="440"></p><h3><strong>ACQUITY UPLC Columns</strong></h3><h5><strong>Increase speed, sensitivity, and resolution, without compromising data integrity</strong></h5><p>Increasing sample throughput, achieving unmatched resolution, and improving analyte sensitivity are priorities for your separation goals. With Waters ACQUITY UPLC Columns, you can meet all your method requirements and substantially reduce your analysis time and cost-per-sample.</p><p>Waters <strong>ACQUITY UPLC Columns’ sub-2-µm particle chemistries</strong> enable chromatographers to harness the separation efficiency improvements at increased flow rates of ultra-performance liquid chromatography (UPLC) technology, thereby improving analyte resolution and sensitivity as well as business productivity and profitability. &nbsp;</p><h4><strong>Overview</strong></h4><ul><li>Best-in-class column efficiency for superior separation speed, sensitivity, and resolution</li><li><strong>8 UPLC particles</strong> of various substrate technologies, including Ethylene Bridged Hybrid (BEH), High Strength Silica (HSS), and Charged Surface Hybrid (CSH)</li><li><strong>22 stationary phases</strong>, including C18, Phenyl-Hexyl, C8, Embedded-Polar, C4, HILIC, Amide, Diol, Cyano, and PFP</li><li><strong>7 application-specific UPLC Column chemistries</strong> for SEC, proteins, peptides, oligonucleotides, glycan, and amino acid analysis</li><li><strong>More than 50 different column dimensions and configurations</strong>, with internal column diameters ranging from 1.0–4.6 mm and column lengths ranging from 30–300 mm</li><li><strong>Prolonged column lifetimes</strong> with optional <strong>VanGuard Cartridges</strong> specifically designed using ACQUITY stationary phases</li><li><strong>Recommended Use: </strong>For improved speed, sensitivity, and resolution in methods development.</li></ul><h4><strong>Particle technology</strong></h4><h5><strong>BEH - Ethylene Bridged Hybrid Particle Technology</strong></h5><p><strong>ACQUITY UPLC BEH </strong>1.7 µm fully porous columns provide superior analyte peak shape, efficiency, and chemical stability to any separation. ACQUITY UPLC BEH Columns are available in both reversed-phase and HILIC separation modes, with chemistries that provide selectivities for a wide range of compounds. With the ruggedness to operate at extreme pH conditions, ACQUITY UPLC BEH Columns enable the separation scientist to use a wide pH range to influence retention, selectivity, and sensitivity for ionizable compounds.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_BEH_technology_c07876b8a3.jpg" alt="Waters: BEH particle technology" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_BEH_technology_c07876b8a3.jpg 170w," sizes="100vw" width="1050" height="964"></p><h5><strong>CSH - Charged Surface Hybrid Particle Technology</strong></h5><p><strong>ACQUITY UPLC CSH™</strong> 1.7 µm fully porous columns provide superior peak shape for basic analytes when using low ionic strength acidic mobile phases (e.g. 0.1% formic acid). With CSH Technology, the controlled low-level positive surface charge provides exceptional peak shape for basic analytes which can be achieved without the use of ion pairing reagents. Typically reversed-phase bonded phases have poor peak shape for basic compounds in formic acid even at analytical mass loads. Built on the rugged Ethylene Bridged Hybrid (BEH) particle, ACQUITY UPLC CSH phases can withstand the toughest operating conditions.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_CSH_technology_ff4ddc1708.jpg" alt="Waters: CSH particle technology" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_CSH_technology_ff4ddc1708.jpg 169w," sizes="100vw" width="1049" height="968"></p><h5><strong>HSS - High Strength Silica (HSS) Particle Technology</strong></h5><p>ACQUITY UPLC HSS 1.8 µm fully porous columns provide expected silica particle-like performance to the UPLC family. The HSS particles’ high surface area, and lower pore volume provide increased retentivity over the hybrid particles. This robust particle technology is available in five uniquely different bonded phases, which truly maximize the selectivity space. The wide array of bonded phases associated with ACQUITY UPLC HSS Columns enable traditional hydrophobic reversed-phase interactions along with dipole-dipole interactions, aromatic interactions, and hydrogen bonding interactions.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_HSS_technology_b12d3ddfab.jpg" alt="Waters: HSS particle technology" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_HSS_technology_b12d3ddfab.jpg 162w," sizes="100vw" width="975" height="936"></p><h4><strong>Get superior peak shape for basic analytes</strong></h4><p>Reversed-phase bonded phases typically have poor peak shape for basic compounds when using formic acid, even at analytical mass loads. However, ACQUITY UPLC CSH Columns are the exception. These rugged UPLC Columns provide superior peak shape for basic analytes with formic acid or other low ionic-strength, acidic mobile phases. The controlled, low-level, positive surface charge bonded to the ethylene-bridged hybrid (BEH) particles provides excellent peak shape for bases—without the need for the use of ion-pairing reagents.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Analysis_of_ziprasidone_peroxide_degradation_on_an_ACQUITY_UPLC_CSH_C18_Column_56909f1dc8.jpeg" alt="Waters: Analysis of ziprasidone peroxide degradation on an ACQUITY UPLC CSH C18 Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Analysis_of_ziprasidone_peroxide_degradation_on_an_ACQUITY_UPLC_CSH_C18_Column_56909f1dc8.jpeg 245w," sizes="100vw" width="1024" height="485"></p><h4><strong>The ruggedness you want, the repeatability you need</strong></h4><p>ACQUITY UPLC BEH 1.7 µm fully porous columns provide superior analyte peak shape, efficiency, and chemical stability to any separation. ACQUITY UPLC BEH Columns are available in both reversed-phase and HILIC separation modes, with chemistries that provide selectivities for a wide range of compounds. With the ruggedness to operate at extreme pH conditions, ACQUITY UPLC BEH Columns enable separation scientists to use a wide pH range to influence retention, selectivity, and sensitivity for ionizable compounds.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_ACQUITY_UPLC_BEH_Columns_can_be_used_at_the_extremes_of_mobile_phase_p_H_1_12_to_enhance_retention_and_specificity_for_complex_samples_that_include_mixtures_of_acidic_basic_and_neutral_analytes_5104d9a155.jpeg" alt="Waters: ACQUITY UPLC BEH Columns can be used at the extremes of mobile phase pH (1-12) to enhance retention and specificity for complex samples that include mixtures of acidic, basic, and neutral analytes." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_ACQUITY_UPLC_BEH_Columns_can_be_used_at_the_extremes_of_mobile_phase_p_H_1_12_to_enhance_retention_and_specificity_for_complex_samples_that_include_mixtures_of_acidic_basic_and_neutral_analytes_5104d9a155.jpeg 195w," sizes="100vw" width="1024" height="823"></p><h4><strong>Achieve flexibility in method development</strong></h4><p>Chromatographic laboratories need to quickly and easily develop robust methods that are compatible with all modern chromatographic detection modes and transferrable to laboratories and sites that operate different LC system platforms. With ACQUITY UPLC CSH and XSelect Columns, method development scientists in all application areas can achieve a wide range of selectivities without compromising performance across attributes, including superior peak shape for basic compounds, low column bleeds, excellent batch-to-batch reproducibility, and high efficiency.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_CSH_Columns_offer_a_wide_range_of_selectivity_differences_large_S_values_733305abf8.jpeg" alt="Waters: CSH Columns offer a wide range of selectivity differences (large S-values)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_CSH_Columns_offer_a_wide_range_of_selectivity_differences_large_S_values_733305abf8.jpeg 136w," sizes="100vw" width="1024" height="1173"></p>

Waters CORTECS Phenyl HPLC Columns

Waters CORTECS Phenyl provides you with ultra-low column MS bleed, long lifetimes and excellent peak shape.

<p><strong>CORTECS Phenyl columns</strong> provide <strong>complimentary selectivity to C18</strong> stationary phases. The particle morphology offers <strong>high efficnecy and lower backpressures</strong> when compared to fully porouse particles of similar particle size. CORTECS Phenyl provides you with <strong>ultra-low column MS bleed</strong>, <strong>long lifetimes</strong> and <strong>excellent peak shape</strong>.</p><h5><strong>Specifications</strong></h5><ul><li><strong>Chemistry:</strong> Phenyl</li><li><strong>Separation Mode: </strong>Reversed Phase</li><li><strong>Particle Substrate:</strong> Silica</li><li><strong>pH Range Min</strong>: 2 pH</li><li><strong>pH Range Max:</strong> 8 pH</li><li><strong>Maximum Pressure:</strong> 18000 psi (1240 Bar)</li><li><strong>Endcapped: </strong>Yes</li><li><strong>Silanol Activity: </strong>Low</li><li><strong>Particle Shape:</strong> Spherical</li><li><strong>Pore Size: </strong>90 Å</li><li><strong>System: </strong>UHPLC, UPLC</li><li><strong>Particle Technology:</strong> Solid core</li><li><strong>USP Classification:</strong> L11</li><li><strong>Carbon Load: </strong>5.9 %</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_CORTECS_C8_Column_68f0f00415.jpg" alt="Waters: CORTECS Phenyl Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_CORTECS_C8_Column_68f0f00415.jpg 234w," sizes="100vw" width="660" height="440"></p><h3><strong>CORTECS Columns</strong></h3><h4><strong>Solid-core columns that live up to their potential.</strong></h4><p>Your lab needs to develop methods for challenging separations even faster. Increase resolution for even your toughest samples with the enhanced column efficiency of <strong>CORTECS solid-core columns</strong>, which provide the flexibility and power you need to rapidly separate a wide array of compounds.</p><p><strong>CORTECS Columns</strong> are available in <strong>reversed-phase and HILIC options</strong> across <strong>seven column chemistries</strong> with <strong>different particle characteristics</strong> and innovative charged surface modifications for 20% faster separations and 25% more resolution at low operating back pressures.</p><h4><strong>Overview</strong></h4><ul><li>Maximize efficiency with <strong>high-performance columns</strong> created using state-of-the-art column packing techniques, bonding and end-capping processes.</li><li>Achieve <strong>greater throughput and speed</strong> than fully porous particle columns.</li><li>Get <strong>simple and seamless transfer</strong> with consistent results across different particle sizes and column configurations.</li><li><strong>Flexibly develop methods for challenging separations</strong> faster with reversed-phase and HILIC options across seven column chemistries.</li><li><strong>Prolong column lifetimes</strong> with optional VanGuard Cartridges and pre-columns specifically designed using CORTECS stationary phases.</li><li><strong>Recommended Use:</strong> To maximize resolution and speed for all LC separations.</li></ul><h4><strong>CORTECS Column Characteristics</strong></h4><h5><strong>CORTECS C18+ Columns</strong></h5><ul><li>General purpose</li><li>High efficiency</li><li>Reversed-phase column</li><li>A positively charged surface delivers excellent peak shape for basic compounds at low pH.</li></ul><h5><strong>CORTECS C18 Columns</strong></h5><ul><li>General purpose</li><li>High efficiency</li><li>Reversed-phase column</li><li>Balanced retention of acids, bases, and neutrals at low and mid-range pH.</li></ul><h5><strong>CORTECS C8 Columns</strong></h5><ul><li>General purpose</li><li>High efficiency</li><li>Reversed-phase column</li><li>Similar selectivity but shorter retentivity when compared to C18 columns.</li></ul><h5><strong>CORTECS T3 Columns</strong></h5><ul><li>General purpose</li><li>High efficiency</li><li>Reversed-phase column</li><li>Enables to use of 100% aqueous mobile phase and increased retention of polar compounds.</li></ul><h5><strong>CORTECS Phenyl Columns</strong></h5><ul><li>High efficiency</li><li>Method development column</li><li>Provides alternate selectivity, particularly for polyaromatic compounds.</li></ul><h5><strong>CORTECS Shield RP18 Columns</strong></h5><ul><li>High efficiency</li><li>Method development column</li><li>Provides alternate selectivity, particularly for phenolic compounds.</li></ul><h5><strong>CORTECS HILIC Columns</strong></h5><ul><li>General purpose</li><li>High efficiency</li><li>HILIC Column</li><li>Offers orthogonal selectivity when compared to reversed-phase columns.</li></ul><h4><strong>Reliable columns. Consistent performance.</strong></h4><p>Get consistent batch-to-batch performance year after year with reliable CORTECS Columns.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Get_consistent_batch_to_batch_reproducibility_with_long_column_lifetimes_4600807215.jpg" alt="Waters: Consistent performance" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Get_consistent_batch_to_batch_reproducibility_with_long_column_lifetimes_4600807215.jpg 227w," sizes="100vw" width="1024" height="704"></p><h4><strong>Method transfer just got easier.</strong></h4><p>Get the versatility you need for seamless method transfer, with consistent results and fully scalable particle sizes for HPLC, UHPLC, and UPLC platforms.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Modernize_and_speed_up_your_existing_methods_2dd7e61390.jpg" alt="Waters: Modernize and speed up your existing methods." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Modernize_and_speed_up_your_existing_methods_2dd7e61390.jpg 191w," sizes="100vw" width="1024" height="837"></p><h4><strong>Increased resolution and increased throughput.</strong></h4><p>Maximize column efficiency and throughput with increased resolution for the toughest samples on any LC system.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Maximize_Column_Efficiency_69800e15cb.jpg" alt="Waters: Maximize Column Efficiency" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Maximize_Column_Efficiency_69800e15cb.jpg 234w," sizes="100vw" width="1024" height="682"></p>

Thermo Scientific Hypersil GOLD Phenyl HPLC Columns

Get excellent retention and unique selectivity for aromatic and moderately polar analytes with Thermo Scientific™ Hypersil GOLD™ Phenyl reversed phase HPLC columns

<p><strong>Get excellent retention and unique selectivity for aromatic and moderately polar analytes with Thermo Scientific™ Hypersil GOLD™ Phenyl reversed phase HPLC columns.&nbsp;</strong></p><p>A butyl (C4) linker in the phenyl bonded phase allows for superior alignment of the phenyl ring with aromatic molecules, thus enhancing pi-pi interactions and improving the retention of the molecules. The C4 linker also provides the stationary phase with moderate hydrophobicity, making it ideal for the separation of analyte mixtures with varying polarity and aromaticity. The outstanding peak shape results in greater sensitivity.</p><h5><strong>Special selectivity</strong></h5><ul><li>Provides selectivity complementary to that provided by alkyl chain phases</li><li>Moderate hydrophobicity compared to C18</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Endcapped:</strong> Yes</li><li><strong>Max. Pressure: </strong>5800 psi (400 bar)</li><li><strong>Packing Material:</strong> Silica</li><li><strong>Stationary Phase:</strong> Phenyl/C4</li><li><strong>Surface Area:</strong> 220 m²/g</li><li><strong>Temperature:</strong> 60°C</li><li><strong>USP Type: </strong>L11</li><li><strong>Carbon Load</strong>: 9%</li><li><strong>Phase:</strong> Reversed Phase</li><li><strong>Pore Size: </strong>175 Å</li><li><strong>pH: </strong>2 to 8</li></ul><h4><strong>About the Hypersil GOLD Family of HPLC Columns</strong></h4><p>Meet the challenges of modern chromatography with state-of-the-art columns that provide outstanding performance and consistent separations. <strong>Twelve different column chemistries</strong> are available so you can optimize separations and maximize productivity. Get outstanding peak shapes in reversed phase, ion exchange, HILIC, or normal phase chromatography.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg 150w," sizes="100vw" width="747" height="775"></p><ul><li><strong>Excellent peak symmetry</strong><ul><li>Hypersil GOLD columns <strong>produce highly symmetrical peaks</strong>, which facilitate the detection of low-level impurities that elute immediately after the main component. When there is even minor tailing, small impurity peaks can elute on the shoulder of the main peak, complicating the integration process.</li></ul></li><li><strong>Narrow peaks </strong>for outstanding efficiency</li><li><strong>Enhanced sensitivity</strong> and improved resolution</li><li><strong>Exceptional reproducibility </strong>for reliable chromatography, column after column</li><li>Solutions for <strong>high-throughput screening</strong></li><li><strong>1.9, 3, and 5 μm particle sizes </strong>for all your separation needs</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns: Peak symmetry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg 149w," sizes="100vw" width="880" height="925"></p>

Thermo Scientific Hypersil GOLD PFP HPLC Columns

Analyze difficult-to-resolve mixtures of halogenated compounds and non-halogenated polar compounds with Thermo Scientific™ Hypersil GOLD™ PFP (pentafluorophenyl) HPLC columns. 

<p><strong>Analyze difficult-to-resolve mixtures of halogenated compounds and non-halogenated polar compounds with Thermo Scientific™ Hypersil GOLD™ PFP (pentafluorophenyl) HPLC columns. These columns provide an alternative selectivity to C18 columns in reversed phase applications with excellent peak shape and sensitivity.</strong></p><h5><strong>Unique selectivity</strong></h5><ul><li>Increased retention and selectivity for positional isomers of halogenated compounds</li><li>Excellent selective analysis of non-halogenated compounds, in particular polar compounds containing hydroxyl, carboxyl, nitro, or other polar groups</li><li>Efficient separation of difficult mixtures containing closely related halogenated and polar compounds</li></ul><p>The introduction of a fluorine group into the stationary phase causes significant changes in solute-stationary phase interaction and increases the selectivity and extra retention.</p><h4><strong>Specifications</strong></h4><ul><li><strong>Endcapped:</strong> Yes</li><li><strong>For Use With: </strong>HPLC</li><li><strong>Max. Pressure: </strong>18130 psi (1250 bar)</li><li><strong>Packing Material:</strong> Spherical, Fully Porous, Ultrapure Silica</li><li><strong>Stationary Phase:</strong> PFP (Pentafluorophenylpropyl)</li><li><strong>Surface Area:</strong> 220 m²/g</li><li><strong>Temperature:</strong> 60°C</li><li><strong>USP Type: </strong>L43</li><li><strong>Carbon Load</strong>: 8%</li><li><strong>Phase:</strong> Reversed Phase</li><li><strong>Pore Size: </strong>175 Å</li><li><strong>pH: </strong>2 to 8</li></ul><h4><strong>About the Hypersil GOLD Family of HPLC Columns</strong></h4><p>Meet the challenges of modern chromatography with state-of-the-art columns that provide outstanding performance and consistent separations. <strong>Twelve different column chemistries</strong> are available so you can optimize separations and maximize productivity. Get outstanding peak shapes in reversed phase, ion exchange, HILIC, or normal phase chromatography.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Columns_41d5984b62.jpg 150w," sizes="100vw" width="747" height="775"></p><ul><li><strong>Excellent peak symmetry</strong><ul><li>Hypersil GOLD columns <strong>produce highly symmetrical peaks</strong>, which facilitate the detection of low-level impurities that elute immediately after the main component. When there is even minor tailing, small impurity peaks can elute on the shoulder of the main peak, complicating the integration process.</li></ul></li><li><strong>Narrow peaks </strong>for outstanding efficiency</li><li><strong>Enhanced sensitivity</strong> and improved resolution</li><li><strong>Exceptional reproducibility </strong>for reliable chromatography, column after column</li><li>Solutions for <strong>high-throughput screening</strong></li><li><strong>1.9, 3, and 5 μm particle sizes </strong>for all your separation needs</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg" alt="Thermo Fisher Scientific: Hypersil GOLD Columns: Peak symmetry" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Hypersil_GOLD_Peak_symmetry_641b946673.jpg 149w," sizes="100vw" width="880" height="925"></p>

Thermo Scientific Accucore PFP HPLC Columns

Improve LC separations of halogenated compounds and nonhalogenated polar analytes using Thermo Scientific™ Accucore™ PFP LC columns. 

<p><strong>Improve LC separations of halogenated compounds and nonhalogenated polar analytes using Thermo Scientific™ Accucore™ PFP LC columns. Rugged 2.6μm solid-core particles enable fast, high-resolution separations at low backpressures.</strong></p><p>Fluorine groups in the PFP stationary phase provide enhanced retention and selectivity for positional isomers of halogenated compounds and for compounds with polar functional groups. Robust bonding technology and automated packing procedures ensure excellent reproducibility and long column lifetimes.</p><h5><strong>Alternative Selectivity</strong></h5><ul><li>Pentafluorophenyl (PFP) phase provides a unique selectivity for halogenated species and nonhalogenated polar compounds.</li></ul><h5><strong>Fast Separations</strong></h5><ul><li>2.6μm core-enhanced technology particles enable operation at high flow rates without generating excessive backpressures.</li></ul><h5><strong>Excellent Peak Shapes for Enhanced Resolution and Sensitivity</strong></h5><ul><li>Solid-core 2.6μm particles and narrow particle size distribution reduce band broadening and improve separation efficiencies.</li><li>High surface coverage of silica minimizes secondary interactions and peak tailing.</li></ul><h5><strong>Low Backpressures</strong></h5><ul><li>Solid-core 2.6μm particles for less backpressure compared to UHPLC sub-2μm particles</li><li>Compatible with conventional HPLC instrumentation and UHPLC platforms</li></ul><h5><strong>Excellent Reproducibility and Robustness</strong></h5><ul><li>Advanced bonding technology</li><li>Automated packing process</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Endcapped:</strong> Yes</li><li><strong>Max. Pressure: </strong>14500 psi (1000 bar)</li><li><strong>Packing Material:</strong> Spherical, Solid Core, Ultrapure Silica</li><li><strong>Particle Shape:</strong> Spherical Solid Core</li><li><strong>Stationary Phase:</strong> PFP (Pentafluorophenylpropyl)</li><li><strong>Surface Area:</strong> 130 m²/g</li><li><strong>Temperature:</strong> 70°C</li><li><strong>USP Type: </strong>L43</li><li><strong>Carbon Load</strong>: 5%</li><li><strong>Phase:</strong> Reversed Phase</li><li><strong>Pore Size: </strong>80 Å</li><li><strong>pH: </strong>2 to 8</li></ul><h3><strong>Accucore HPLC and UHPLC Columns</strong></h3><h4><strong>Resolve impurities without feeling the pressure</strong></h4><p>Thermo Scientific Accucore HPLC and UHPLC columns provide ultimate core performance, allowing you to maximize your investment. Solid-core particles deliver UHPLC performance, with superb resolution delivering back-pressure compatible with HPLC instrumentation. A wide range of phases help meet all your separation needs, while our columns are exceptionally rugged and easy to use.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Accucore_columns_26e0ffa8d5.jpg" alt="Thermo Fisher Scientific: Accucore columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Accucore_columns_26e0ffa8d5.jpg 156w," sizes="100vw" width="708" height="711"></p>

Thermo Scientific Accucore Phenyl-X HPLC Columns

Achieve fast, high-resolution separations of aromatic compounds using Thermo Scientific™ Accucore™ Phenyl-X columns.

<p><strong>Achieve fast, high-resolution separations of aromatic compounds using Thermo Scientific™ Accucore™ Phenyl-X columns. Rugged 2.6μm solid-core particles enable fast, high-efficiency separations at low backpressures. The phenyl-X alkyl aromatic bonded phase offers unique reversed-phase shape selectivity with high aromatic selectivity and is compatible with highly aqueous mobile phases. Robust bonding technology and automated packing procedures ensure excellent reproducibility and long column lifetimes.</strong></p><h5><strong>Unique Selectivity and Enhanced Retention for Aromatic Compounds</strong></h5><ul><li>Proprietary alkyl aromatic bonded phase provides unique selectivity compared to other reversed phase materials such as C18 or hexyl<strong>.</strong></li></ul><h5><strong>Compatible with Highly Aqueous Mobile Phases</strong></h5><ul><li>Specially designed bonded phase will not undergo phase collapse in highly aqueous mobile phase.</li></ul><h5><strong>Fast Separations</strong></h5><ul><li>2.6μm core-enhanced technology particles enable operation at high flow rates without generating excessive backpressures.</li></ul><h5><strong>Excellent Peak Shapes for Enhanced Resolution and Sensitivity</strong></h5><ul><li>Solid-core 2.6μm particles and narrow particle size distribution reduce band broadening and improve separation efficiencies.</li><li>High surface coverage of silica minimizes secondary interactions and peak tailing.</li></ul><h5><strong>Low Backpressures</strong></h5><ul><li>Solid-core 2.6μm particles for less backpressure compared to UHPLC sub-2μm particles</li><li>Compatible with conventional HPLC instrumentation and UHPLC platforms</li></ul><h5><strong>Excellent Reproducibility and Robustness</strong></h5><ul><li>Advanced bonding technology</li><li>Automated packing process</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Endcapped:</strong> Yes</li><li><strong>Max. Pressure: </strong>14500 psi (1000 bar)</li><li><strong>Packing Material:</strong> Spherical, Solid Core, Ultrapure Silica</li><li><strong>Stationary Phase:</strong> Phenyl</li><li><strong>Surface Area:</strong> 130 m²/g</li><li><strong>Temperature:</strong> 70°C</li><li><strong>USP Type: </strong>N/A</li><li><strong>Carbon Load</strong>: 6%</li><li><strong>Phase:</strong> Reversed Phase</li><li><strong>Pore Size: </strong>80 Å</li><li><strong>pH: </strong>2 to 8</li></ul><h3><strong>Accucore HPLC and UHPLC Columns</strong></h3><h4><strong>Resolve impurities without feeling the pressure</strong></h4><p>Thermo Scientific Accucore HPLC and UHPLC columns provide ultimate core performance, allowing you to maximize your investment. Solid-core particles deliver UHPLC performance, with superb resolution delivering back-pressure compatible with HPLC instrumentation. A wide range of phases help meet all your separation needs, while our columns are exceptionally rugged and easy to use.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Accucore_columns_26e0ffa8d5.jpg" alt="Thermo Fisher Scientific: Accucore columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Accucore_columns_26e0ffa8d5.jpg 156w," sizes="100vw" width="708" height="711"></p>

Thermo Scientific Syncronis Phenyl  HPLC Columns

Achieve repeatable and consistent liquid chromatography (LC) separations of aromatic compounds using Thermo Scientific™ Syncronis™ Phenyl LC Columns. 

<p><strong>Achieve repeatable and consistent liquid chromatography (LC) separations of aromatic compounds using Thermo Scientific™ Syncronis™ Phenyl LC Columns. High surface area silica, dense stationary phase coverage, and double end-capping minimize secondary interactions and deliver reproducible high-resolution separations. The Phenyl-bonded aromatic phase offers alternative selectivity to C18 columns and is particularly useful for optimized retention of aromatic analytes.</strong></p><p>Manufactured and rigorously tested in ISO 9000 facilities, these columns are designed to meet a range of analytical needs including fast method development, quantitative analysis, and quality control.</p><h5><strong>Highly Reproducible Separations</strong></h5><ul><li>Rigorously tested stationary phase bonded to the highest quality silica ensures consistent, predictable LC performance.</li></ul><h5><strong>Excellent Peak Shapes for Enhanced Resolution and Sensitivity</strong></h5><ul><li>Dense surface coverage of silica minimizes secondary interactions and peak tailing</li><li>Double endcapped for extra surface coverage</li></ul><h5><strong>Exceptional Column-to-Column Consistency</strong></h5><ul><li>Manufactured, packed and tested in ISO-9000-accredited facilities</li><li>Every column individually tested to meet stringent retention, efficiency, and peak symmetry specifications</li><li>Enhanced automated packing process</li></ul><h5><strong>Alternative Selectivity</strong></h5><ul><li>Enhanced retention of aromatic compounds</li></ul><h5><strong>Available in Three Particle Sizes</strong></h5><ul><li>1.7μm for rapid ultrahigh-performance LC (UHPLC) separations</li><li>3μm and 5μm for more traditional HPLC analysis</li></ul><h4><strong>Specifications</strong></h4><ul><li><strong>Column type:</strong> Reversed Phase</li><li><strong>Endcapped: </strong>Yes</li><li><strong>Max. Pressure:</strong> 5800 psi (400 bar)</li><li><strong>Packing Material:</strong> Spherical, Fully Porous, Ultrapure Silica</li><li><strong>Stationary phase:</strong> Phenyl</li><li><strong>USP Type:</strong> L11</li><li><strong>Surface Area:</strong> 320 m<sup>2</sup>/g</li><li><strong>Temperature:</strong> 60°C</li><li><strong>Carbon load:</strong> 11%</li><li><strong>Phase:</strong> Reversed Phase,</li><li><strong>Pore Size: </strong>100 Å</li><li><strong>pH: </strong>2 to 8</li></ul><h4><strong>Syncronis HPLC and UHPLC Columns</strong></h4><h5><strong>Enter a new world of chromatography</strong></h5><p>When developing a new method, one of the most important goals for the chromatographer is to achieve a consistent, reproducible separation. This makes selecting an HPLC column that offers highly-reproducible results essential to attaining this goal.</p><h5><strong>Features of Syncronis columns</strong></h5><p>Thermo Scientific Syncronis LC columns achieve high levels of consistency and reproducibility through:</p><ul><li>Highly-pure, high-surface-area silica</li><li>Dense bonding and double endcapping</li><li>Stringent manufacturing and testing protocols</li></ul>

Phenomenex Gemini C6-Phenyl HPLC Columns

Gemini C6-Phenyl HPLC phase provides aromatic selectivity with low bleed performance, making it ideal for LC/MS analysis of aromatic, polar, and basic compounds under high pH conditions.

<p><strong>Gemini C6-Phenyl HPLC phase has a phenyl group bound to the organo-silica surface using a 6-carbon chain for a low bleed aromatic selective phase. Gemini C6-Phenyl is well suited for LC/MS applications.</strong></p><h5><strong>Key features:</strong></h5><ul><li><strong>Carbon Load: </strong>12 %</li><li><strong>Surface Area (m²/g):</strong> 375</li><li><strong>Particle Size: </strong>3, 5</li><li><strong>Recommended Use:</strong> Separation of aromatic, polar, or basic compounds under high pH conditions</li></ul><h3><strong>Gemini HPLC Columns</strong></h3><h4><strong>Twin-NX technology HPLC columns. Extend your column lifetime</strong></h4><p>Gemini columns are rugged reversed-phase HPLC and PREP LC columns that offer extended lifetime at pH 1-12 conditions and excellent stability for reproducible, high-efficiency separations. The Gemini family contains a variety of useful alkyl and phenyl phases bonded to fully porous organo-silica particles.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Gemini_HPLC_Columns_936267c483.jpg" alt="Phenomenex: Gemini Twin Technology" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Gemini_HPLC_Columns_936267c483.jpg 134w," sizes="100vw" width="349" height="405"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Gemini_HPLC_Columns_2_e67e00cc54.jpg" alt="Phenomenex: Gemini-NX Twin Technology" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Gemini_HPLC_Columns_2_e67e00cc54.jpg 134w," sizes="100vw" width="349" height="405"></p><p>Each Gemini column is supplied with a Certificate of Quality Assurance (CQA) indicating testing conditions, operating parameters, and column details.</p>

Products from category Phenyl HPLC columns - page 1

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