Thermo Scientific™ ISQ™ EC Single Quadrupole Mass Spectrometer
Add mass spectrometry (MS) to your IC and LC analyses for access to the valuable data that only MS can provide. The new, easy-to-use Thermo Scientific™ ISQ™ EC Single Quadrupole Mass Spectrometer seamlessly integrates with ion chromatography (IC) and high performance liquid chromatography (HPLC) systems. Both novices and experts alike can quickly master MS to gain more insights from every sample.
Gain more insights
- Higher sensitivity and more accurate quantitation
- Chromatographic peak mass confirmation, eliminating false negatives and false positives
Resolve complexity
- Improved resolution of analytes in complex matrices
- Better selectivity
- Resolve co-eluting peaks using their mass-to-charge ratio
Easily mastered
- Save time spent on user training with integrated tools to help master MS
- Experience hassle-free, seamless integration with your IC or LC system
- Save time using the Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software for data analysis, which also has embedded control of the ISQ EC mass spectrometer
Thermo Scientific™ ISQ™ EM Single Quadrupole Mass Spectrometer
Adding mass spectrometry (MS) to your liquid chromatography (LC) analyses gives you access to the valuable data that only MS can provide. The new, easy-to-use ISQ™ EM Single Quadrupole Mass Spectrometer seamlessly integrates with LC systems for reliable, robust, and easy LC-MS routine analysis with an extended mass range for more flexibility. Detect and quantify a variety of analytes by choosing to use either heated electrospray ionization (HESI) or atmospheric pressure chemical ionization (APCI). Integrated software allows both novices and experts to quickly master MS to gain more insights from every sample.
Gain more insights
- Extended mass range enables you to detect and quantify small and large molecules
- Durable atmospheric pressure ionization (API) source with two interchangeable probes included, enabling HESI or dual HESI/APCI
- Sensitive and accurate quantitation of more samples
- Chromatographic peak mass confirmation to eliminate false negatives and false positives
Resolve complexity
- Consistent response even with complex matrices
- Better selectivity and sensitivity with chromatographic peak mass confirmation
- Resolution of co-eluting peaks via mass-to-charge ratio
Easy mastery
- Reduce time spent on user training with integrated tools to help master MS
- Unique software translates analyte physical properties into optimal method parameters, helping novice and experts develop methods and improve productivity
- Hassle-free, seamless integration with existing LC systems
- Facilitate data analysis with Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software, which features embedded control of the ISQ EM mass spectrometer
Key Features ISQ™ EC/EM Single Quadrupole Mass Spectrometers:
- Mass Range:
- EC: 10–1250 m/z with unit mass resolution
- EM: 10–2000 m/z with unit mass resolution
- Polarity Switching: 25 ms (in HESI mode)
- Scan Rate: Up to 20,000 Da/sec
- Sensitivity:
- HESI Positive: 10 pg Reserpine, 400:1 RMS at 400 μL/min
- HESI Negative: 20 pg p-Nitrophenol, 500:1 RMS at 400 μL/min
- Gas Requirements: Nitrogen (≥ 99% purity), 30 L/min @ 90–110 psig
- Power Supply: 100–240 V, 50/60 Hz
- Dimensions: 52 (H) × 42 (W) × 91 (D) cm
- Weight: Approx. 71 kg (157 lb)
- Unit Size: Each


