The Thermo Scientific Nicolet™ iS™ 20 FTIR Spectrometer represents a next-generation FTIR platform designed for fast and accurate identification of mixtures, contaminants, and trace components across applications including QA/QC, pharmaceuticals, polymers, and forensics.
At the core of the system is the LightDrive™ Optical Engine, integrating the source, laser, interferometer, and detector into a single optimized module. This design delivers high spectral resolution (<0.25 cm⁻¹) and a signal-to-noise ratio up to 50,000:1, enabling detection of low-level components.
The instrument features a touchscreen interface with multi-color LED status indicators (ready / scan / alert) for intuitive operation. A sealed and purge-ready optical bench ensures long-term stability even in demanding environments.
The system supports cloud-enabled workflows via Thermo Fisher Cloud and uses OMNIC™ / OMNIC Specta™ software, including a library of >9,000 spectra for rapid unknown identification.
Key Features
- LightDrive™ optical engine (source, laser, interferometer, detector)
- Spectral resolution < 0.25 cm⁻¹
- Signal-to-noise ratio up to 50,000:1
- Touchscreen interface with LED status indicators
- 10-year warranty on source, laser, and interferometer
- High data reproducibility (stable IR source)
- Sealed, purge-ready optics
- Cloud connectivity (Thermo Fisher Cloud)
- OMNIC™ and OMNIC Specta™ software (>9,000 spectra library)
- Automated validation (IQ/OQ, pharmacopeias)
- Wide accessory compatibility (SMART, microscopy, TGA-IR)
Technical Specifications
Optics and Performance
- Spectral range:
- 7800–350 cm⁻¹ (standard KBr)
- 11,000–375 cm⁻¹ (XT-KBr extended range)
- Spectral resolution: < 0.25 cm⁻¹
- Signal-to-noise ratio: 50,000:1
- Laser: solid-state diode laser (10-year warranty)
- Beamsplitter:
- KBr/Ge (standard)
- XT-KBr/Ge (optional)
Detection and Sources
- Detector:
- DTGS (standard)
- optional high-sensitivity detectors (e.g., MCT)
- Source:
- stabilized IR source (non-migrating hot spot)
- optional tungsten/halogen
Construction and Validation
- Optical system: sealed and purge-ready
- Validation: integrated SPV, ASTM/NIST traceable
- Compliance:
- USP / Ph. Eur. / JP / CP
- 21 CFR Part 11
Interface and Software
- USB 2.0
- Thermo Fisher Cloud
- Software: OMNIC™ / OMNIC Specta™
Dimensions and Weight
- Dimensions: 570 × 550 × 250 mm
- Weight: 32 kg
Electrical
- 100–240 V, 50–60 Hz


