Maintain consistent, predictable separations for your scale up purification needs with Thermo Scientific™ Syncronis™ HILIC preparative HPLC columns for polar and hydrophilic analytes. Highly pure, high surface area silica and dense stationary phase coverage minimize secondary interactions and deliver reproducible high-resolution separations.
The zwitterionic stationary phase results in a neutral, highly polar surface and provides optional selectivity to C18 columns without ion-pairing or derivatization. Our columns come in a wide range of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed.
Alternative Selectivity
- Zwitterionic bonded phase enhances retention of polar and hydrophilic analytes.
- No need for ion-pair or derivatization.
- Enhanced sensitivity with MS detection.
- Highly organic mobile phase facilitates desolvation in ESI-MS
Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.
Standard Threaded and Standard Flange Hardware
- Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
- Standard threaded hardware for column i.d. < 40mm.
- Standard flange hardware for column i.d. ≥ 40mm.
- Standard hardware can be modified on request to be compatible with SFC.
XtendedLife Hardware
- Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
- Compatible with SFC and is available in dimensions up to 50mm i.d.
Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.
Specifications
- Column type: HILIC
- Endcapped: No
- Max. Pressure: 2000 psi (140 bar)
- Packing Material: Spherical, Fully Porous, Ultrapure Silica
- Stationary phase: Zwitterionic
- Surface Area: 320 m2/g
- Temperature: 60°C
- Carbon load: 5%
- Phase: HILIC
- Pore Size: 100 Å
- pH: 2 to 8
Syncronis HPLC and UHPLC Columns
Enter a new world of chromatography
When developing a new method, one of the most important goals for the chromatographer is to achieve a consistent, reproducible separation. This makes selecting an HPLC column that offers highly-reproducible results essential to attaining this goal.
Features of Syncronis columns
Thermo Scientific Syncronis LC columns achieve high levels of consistency and reproducibility through:
- Highly-pure, high-surface-area silica
- Dense bonding and double endcapping
- Stringent manufacturing and testing protocols
