Ensure consistent, predictable separations of polar and hydrophilic analytes with Thermo Scientific™ Syncronis™ HILIC LC Columns. Highly pure, high surface area silica and dense stationary phase coverage minimize secondary interactions and deliver reproducible high-resolution separations. The zwitterionic stationary phase results in a neutral, highly polar surface and provides alternative selectivity to C18 columns without ion-pairing or derivatization. The highly organic mobile phases used with Syncronis HILIC phases facilitate efficient desolvation in ESI-MS detection and improved sensitivity.
Manufactured and rigorously tested in ISO 9000 facilities, these columns are designed to meet a range of analytical needs including fast method development, quantitative analysis and quality control.
Highly Reproducible Separations
- Rigorously tested stationary phase bonded to the highest quality silica ensures consistent, predictable LC performance
Excellent Peak Shapes for Enhanced Resolution and Sensitivity
- Dense surface coverage of silica minimizes secondary interactions and peak tailing
Exceptional Column-to-Column Consistency
- Manufactured, packed, and tested in ISO-9000-accredited facilities
- Every column individually tested to meet stringent retention, efficiency, and peak symmetry specifications
- Enhanced automated packing process
Alternative Selectivity
- Zwitterionic bonded phase enhances retention of polar and hydrophilic analytes
- No need for ion-pair or derivatization
Enhanced Sensitivity with MS Detection
- Highly organic mobile phase facilitates desolvation in ESI-MS
Available in Three Particle Sizes
- 1.7μm for rapid ultrahigh-performance LC (UHPLC) separations
- 3μm and 5μm for more traditional HPLC analysis
Specifications
- Column type: HILIC
- Max. Pressure: 5800 psi (400 bar)
- Packing Material: Spherical, Fully Porous, Ultrapure Silica
- Stationary phase: Zwitterionic
- Surface Area: 320 m2/g
- Temperature: 60°C
- Carbon load: 5%
- Phase: HILIC
- Pore Size: 100 Å
- pH: 2 to 8
Syncronis HPLC and UHPLC Columns
Enter a new world of chromatography
When developing a new method, one of the most important goals for the chromatographer is to achieve a consistent, reproducible separation. This makes selecting an HPLC column that offers highly-reproducible results essential to attaining this goal.
Features of Syncronis columns
Thermo Scientific Syncronis LC columns achieve high levels of consistency and reproducibility through:
- Highly-pure, high-surface-area silica
- Dense bonding and double endcapping
- Stringent manufacturing and testing protocols
