Separate cationic molecules with powerful adjustable selectivity control using Thermo Scientific™ Acclaim™ Mixed-Mode WCX-1 LC columns. The silica-based stationary phase features a hydrophobic alkyl chain with a carboxyl terminus that provides both hydrophobic reversed-phase and weak cation-exchange properties. This multimode separation mechanism delivers simultaneous separation of basic and neutral compounds. By independently or simultaneously tuning the mobile phase ionic strength, pH, and organic modifier, you can control the selectivity of ionizable and neutral compounds.
Retains and Separates Highly Hydrophilic to Highly Hydrophobic Basic Molecules
- Multimode retention mechanism: reversed-phase, weak cation-exchange, anion-exclusion, and HILIC modes
- Selectivity complementary to C18 reversed-phase columns
- Efficient primary column for a variety of basic analytes; also an ideal column for secondary methods development
- Versatile in applications that require different selectivities
- Symmetrical peak shapes and excellent efficiency
- Stable between pH 2.5 and 7.5
- Available in 3 and 5μm particle sizes with an average pore diameter of 120Å
Specifications
- Column type: Mixed mode
- For use with: RPLC, Cation Exchange, Ion-Exclusion, HILIC
- Max. Pressure: 6000 psi (415 bar)
- Packing Material: Silica
- Stationary phase: Hydrophobic Alkyl Chain with a Carboxyl Terminus
- USP Type: L85
- Surface Area: 300 m²/g
- Temperature: 50°C
- Phase: Reversed Phase, Ion Exchange, Ion Exclusion, HILIC
- Pore Size: 120 Å
- pH: 2.5 to 7.5
About the Acclaim Family of HPLC Columns
Achieve the high standards set by modern HPLC and LC/MS methods with the Acclaim family of reversed-phase columns. These silica-based columns with advanced column bonding and endcapping technologies provide complementary selectivity, high column efficiencies, and ultra-high resolution for a wide variety of applications.
- Broad spectrum of stationary phases, including conventional C8 and C18 phases, polar embedded phases, and specialty phases including wide-pore, are available to meet your specific application needs
- Performance tested to ensure high quality and reliability for pharmaceutical, biopharmaceutical, environmental, food, and other industrial chromatographic separations
Thermo Fisher Scientific: Broad range of HPLC and UHPLC columns
