Optimize your productivity
In today’s challenging research and production environments, you are being asked to be more productive without increasing spending or compromising quality.
At the same time, advancements and innovations are needed to improve operational efficiency and performance. How do you accomplish this? It’s easy with the Thermo Scientific™ Vanquish™ High-throughput LC systems built for enhanced productivity. Vanquish High-throughput LC systems combine individual Vanquish components and software wizards to deliver increased throughput or detector utilization.
Thermo Scientific Vanquish Tandem LC Systems.
Two flow paths for maximized productivity
Your laboratory may be facing increased pressure to improve working efficiency and deal with limiting resources, such as budget, space, or manpower. Vanquish High-throughput LC systems are designed to overcome these limitations by providing multiple flow paths for parallelization of specific stages of the LC run.
Thermo Scientific Vanquish Tandem LC Systems.
Unique dual technology
The Vanquish platform contains two unique dual modules. Vanquish dual pumps merge two individual, low pressure mixing pumps in one housing enabling separate eluents and gradients for each pump.
Vanquish dual split samplers possess two independently controlled injection units including separate injection valves and injection needles. Used in Dual LC and LC-MS workflows only, this enables high throughput and extensive sample characterization workflows.
Two configurations to best serve your needs
Vanquish High-throughput workflows are configured with Thermo Scientific™ Vanquish™ Core system, Thermo Scientific™ Vanquish™ Flex system or Thermo Scientific™ Vanquish™ Horizon system modules. Both workflows make use of two pumps to increase instrument productivity.
Thermo Scientific Vanquish Tandem LC Systems: Two configurations to best serve your needs.
Vanquish Duo UHPLC Systems
- Supported systems:
- Sampler: Dual split sampler
- Detector: Two out of the complete detector portfolio
- Software control:
Vanquish Tandem LC Systems
- Supported systems:
- Sampler: Split sampler
- Detector: One out of the complete detector portfolio and/or one mass spectrometer
- Software control:
- Chromeleon CDS
- Standard System Integration for Thermo Scientific™ Xcalibur™ software
Vanquish Tandem LC systems
Gradient separations are commonly used in LC or LC-MS. Column reconditioning, such as washing and re-equilibration, takes time and reduces your overall sample throughput. The Vanquish Tandem LC systems eliminate these limitations and improve productivity by:
- Increasing sample throughput without modifying a validated method
- Improving return on investment by maximizing mass spectrometer utilization
- Reducing column carry over through extended column washing without sacrificing throughput
- Simplifying method setup with automatic method conversion from your original gradient method
Thermo Scientific Vanquish Tandem LC Systems.
Throughput increase using Tandem LC
Thermo Scientific Vanquish Tandem LC Systems: Throughput increase by Tandem LC is between 10–80% for most common conditions.
The Vanquish Tandem LC system splits the analysis between two pumps and two columns. One pump delivers the analytical gradient while the second pump runs the reconditioning gradient. This configuration allows you to use two identical columns to run your sequence faster without compromising data quality.
Thermo Scientific Vanquish Tandem LC Systems: Reproducible results for the Thermo Scientific™ Vanquish™ Horizon Tandem UHPLC system—Thermo Scientific™ Q Exactive™ HF hybrid quadrupole-Orbitrap™ mass spectrometer showing an overlay of five total ion current chromatograms. The sample shown is digested Infliximab using the Thermo Scientific™ SMART ™ Digest Kit.
Simply upgrade your method
Implementing Tandem LC-MS into your workflow is easy with compliance-ready Chromeleon software for LC or LC-MS users and Thermo Scientific Standard Instrument Integration (SII) for Thermo Scientific Xcalibur software for LC-MS users.
A simple dedicated instrument method wizard enables you to create new methods without the need for additional training.
Thermo Scientific Vanquish Tandem LC Systems.
Thermo Scientific Vanquish Tandem LC Systems: Chromeleon CDS and SII for Xcalibur guides users through the implementation of a Tandem LC or LC-MS method with automatic system volume considerations and gradient formation of the reconditioning pump.
Thermo Scientific LC portfolio overview
Thermo Scientific LC portfolio overview.
