Impurity profiling and characterization of intact biologic fragments is a challenging undertaking because of the need to identify very small differences between variants. Both bioZen Intact columns contain skillfully manufactured large pore core-shell particles that provide narrower, taller peaks in conjunction with higher resolution between the target HC/LC, Fc/Fab, or isoforms.
Phenomenex: Biozen Intact XB-C8 HPLC Column
- Separation Mode: Reversed Phase
- Particle size: 3.6
- Recommended Use: Fast separation of intact and subunit separation with hydrophobic selectivity
Phenomenex Biozen Biologics LC Columns
With a new titanium BioTi™ biocompatible hardware to minimize priming, four particle platforms for optimal versatility and nine particle chemistries to maximize selectivity and sensitivity, Biozen UHPLC/HPLC columns for protein analysis are seamlessly designed to bring peace of mind to your analysis of biologics through:
- Charge Variant Analysis
- Aggregate Analysis
- Peptide Mapping
- Intact Mass Analysis
- Intact and Subunit Analysis
- Glycan Analysis
- Peptide Quantitation
- Drug Antibody Ratio (DAR)
- Oligonucleotide Characterization
Biocompatible Flow Path with BioTi™ Hardware
Keep your mind at ease knowing that we’ve minimized the need for priming with a new titanium infused biocompatible hardware and frit that doesn’t interfere with protein or peptide integrity!
Phenomenex: BioTi Hardware
4 Advanced Particle Platforms
All four of the Biozen particle platforms were individually designed and built by Phenomenex to take advantage of integral levels of performance, ruggedness, and reproducibility for protein characterization applications. Individually, each platform differs in the proprietary processing techniques used to control particle size and morphology.
Phenomenex: Advanced Particle Platforms
