High Efficiency Protein A Affinity Columns for the LC-MS and 2D LC-MS Analysis of mAb and msAb

Application Note High-Throughput Native HRMS ProA-MS Analysis of mAb Variants in Cell-Culture Samples Stephan M. Koza, Matthew A. Lauber, Stephen J. Shiner Waters Corporation, United States Published on January 21, 2025 Abstract The use of rapid Protein-A (ProA) 1-minute elution…

Application Note Extended Gradients with Efficient Protein A Columns for the ProA-MS Analysis of mAb and msAb Variants Stephan M. Koza, Chen Gao, Matthew A. Lauber, Stephen J. Shiner Waters Corporation, United States Published on October 23, 2025 Abstract Here,…

Application note | 003310 Biopharma Monitoring of multiple quality attributes of intact monoclonal antibodies from bioreactors by switchable 2D-LC-MS Authors Application benefits Maria Grübner , Kai Scheffler , 1 1 • Heart-cut 2D-LC with protein A affinity chromatography (ProA) of…

Application note | 004276 Biopharma Monitoring monoclonal antibody bioproduction processes with 2D-LC-UV Author Application benefits Maria Grübner, Thermo Fisher Scientific, • Heart-cut 2D-LC with protein A affinity chromatography (ProA) of cell culture samples enables titer determination and purification for subsequent…