Chromatography Column Frits with MaxPeak High Performance Surfaces Prevent Nonspecific Binding of Nucleic Acids

Application Note A New Alternative to Gel Electrophoresis: Higher Resolution and Faster Analysis of Large Nucleic Acids by Rigorously Designed GTxResolveTM 250 Å Slalom Columns Jamuna Vaishnav, Kennedy Sawyer, Fabrice Gritti, Mandana Fasth, Christian Reidy, MingCheng Xu, Kevin Wyndham, Balasubrahmanyam…

Application Note Enhancing Size-Exclusion Chromatography of Large Biomolecular Analytes With Rigorously Designed GTxResolve™ Premier SEC 1000 Å 3 µm Columns Abraham S. Finny, Lavelay Kizekai, Kristine Camacho, Oksana T'choul, Justin McLaughlin, Steven Byrd, MingCheng Xu, Balasubrahmanyam Addepalli, Matthew A. Lauber…

Application Note Rapid and Sensitive Detection of dsRNA Contaminants in mRNA Using the GTxResolve™ 250Å Slalom Chromatography Column Jamuna Vaishnav, Matthew Lauber, Balasubrahmanyam Addepalli Waters Corporation, United States Published on August 29, 2025 Abstract Discovery and development of messenger RNA…

Application Note Improved Chromatographic Analysis of Oligonucleotides with ACQUITY PREMIER Oligonucleotide BEH C18 Columns Martin Gilar, Zhimin Li, Jason MacLean Waters Corporation Abstract This application note illustrates sources of oligonucleotide loss due to adsorption on metallic column hardware (frits). Solutions,…